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International Journal of Urology: Official Journal of the Japanese Urological Association

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https://www.readbyqxmd.com/read/28636262/increased-renal-concentrating-ability-after-long-term-oral-desmopressin-lyophilisate-treatment-contributes-to-continued-success-for-monosymptomatic-nocturnal-enuresis
#1
Hirokazu Ikeda, Tsuneki Watanabe, Keiichi Isoyama
OBJECTIVES: To investigate renal concentrating ability after long-term fast-melting oral desmopressin lyophilisate treatment in children with monosymptomatic nocturnal enuresis. METHODS: The present retrospective study involved 58 children (43 boys, 15 girls; aged 6-12 years) with nocturnal enuresis receiving oral desmopressin lyophilisate. After treatment for 4 weeks with a complete response, patients were placed on a reduced dose of 120 μg on alternate days. Moring urine osmolality was measured using urine samples obtained after medication and non-medication dry nights...
June 21, 2017: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/28636222/recent-progress-in-immunotherapy-for-urological-cancer
#2
REVIEW
Wataru Obara, Renpei Kato, Yoichiro Kato, Mitsugu Kanehira, Ryo Takata
Cancer immunotherapy for urological tumors had made progress for several decades, but recent advances in immunotherapy, as therapeutic vaccines or immune checkpoint inhibitors, have drastically changed the present treatment strategy. Recently, nivolumab and atezolizumab have been approved by the Food and Drug Administration for treatment of urological cancers. Additional immune checkpoint inhibitors and vaccines are being tested in clinical trials. Despite advances in these therapeutic modalities, benefits are limited to a subset of patients...
June 21, 2017: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/28636142/clinical-development-of-immunotherapy-for-prostate-cancer
#3
REVIEW
Masanori Noguchi, Noriko Koga, Tsukasa Igawa, Kyogo Itoh
Prostate cancer is the most common cancer in men, and the second leading cause of cancer-related death in Western countries. Prostate cancer-related death occurs in patients with metastatic castration-resistant prostate cancer. Although several new drugs for castration-resistant prostate cancer have been approved, each of these has prolonged survival by just a few months. Consequently, new therapies are sorely needed. Recently, it has been recognized that immunotherapy is an effective treatment for prostate cancer patients...
June 21, 2017: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/28636083/editorial-comment-to-predictive-value-of-different-prostate-specific-antigen-based-markers-in-men-with-baseline-total-prostate-specific-antigen-2-0-ng-ml
#4
Yasuhide Kitagawa
No abstract text is available yet for this article.
June 21, 2017: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/28627033/silodosin-versus-naftopidil-in-the-treatment-of-premature-ejaculation-a-prospective-multicenter-trial
#5
Yoshikazu Sato, Toshikazu Otani, Toshiyasu Amano, Tohru Araki, Nobuyuki Kondou, Masanori Matsukawa, Musashi Tobe, Kazunori Haga, Kousuke Uchida, Ichiya Honma
OBJECTIVES: To determine the efficacy of two α1-adrenoceptor antagonists with different affinities for α1-adrenoceptor subtypes, silodosin and naftopidil, in the treatment of premature ejaculation. METHODS: This was a prospective, open-label, multicenter trial. A total of 26 patients with untreated acquired premature ejaculation were enrolled. Premature ejaculation was defined based on the International Society for Sexual Medicine recommendation. Patients self-administered on demand silodosin 4 mg or naftopidil 25 mg 1 h before intercourse, alternating drugs at least three times each...
June 18, 2017: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/28626955/expression-profile-of-urothelial-transcription-factors-in-bladder-biopsies-with-interstitial-cystitis
#6
Kanya Kaga, Ken-Ichi Inoue, Mayuko Kaga, Tomohiko Ichikawa, Tomonori Yamanishi
OBJECTIVES: To characterize interstitial cystitis pathology based on the expression profile of urothelial tissue-specific master transcription factors. METHODS: Bladder carcinoma cell lines derived from the urothelial stem cells (epithelial or mesenchymal) were used to identify candidate urothelial master transcription factors. Gene expression was measured with quantitative reverse transcription polymerase chain reaction. From the initial screening of 170 transcription factors (human homologs of Drosophila segmentation genes and known master transcription factors from a database), 28 transcription factors were selected...
June 18, 2017: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/28626935/editorial-comment-to-substitution-urethroplasty-using-oral-mucosa-graft-for-male-anterior-urethral-stricture-disease-current-topics-and-reviews
#7
Katsumi Shigemura, Masato Fujisawa
No abstract text is available yet for this article.
June 18, 2017: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/28620955/editorial-comment-from-dr-teishima-and-dr-matsubara-to-estimated-glomerular-filtration-rate-on-postoperative-day-1-is-associated-with-renal-functional-outcome-after-percutaneous-renal-cryoablation-for-renal-tumors
#8
Jun Teishima, Akio Matsubara
No abstract text is available yet for this article.
June 15, 2017: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/28600877/stepwise-algorithm-using-computed-tomography-and-magnetic-resonance-imaging-for-diagnosis-of-fat-poor-angiomyolipoma-in-small-renal-masses-development-and-external-validation
#9
Hajime Tanaka, Yasuhisa Fujii, Hiroshi Tanaka, Junichiro Ishioka, Yoh Matsuoka, Kazutaka Saito, Sho Uehara, Noboru Numao, Takeshi Yuasa, Shinya Yamamoto, Hitoshi Masuda, Junji Yonese, Kazunori Kihara
OBJECTIVES: To develop a stepwise diagnostic algorithm for fat-poor angiomyolipoma in small renal masses. METHODS: Two cohorts of small renal masses <4 cm without an apparent fat component that was pathologically diagnosed were included: 153 cases (18 fat-poor angiomyolipomas/135 renal cell carcinomas) for model development and 71 cases (seven fat-poor angiomyolipomas/59 renal cell carcinomas/5 oncocytomas) for validation. Dynamic contrast-enhanced computed tomography, magnetic resonance imaging and clinical findings were analyzed...
June 10, 2017: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/28600871/substitution-urethroplasty-using-oral-mucosa-graft-for-male-anterior-urethral-stricture-disease-current-topics-and-reviews
#10
REVIEW
Akio Horiguchi
Male anterior urethral stricture is scarring of the subepithelial tissue of the corpus spongiosum that constricts the urethral lumen, decreasing the urinary stream. Its surgical management is a challenging problem, and has changed dramatically in the past several decades. Open surgical repair using grafts or flaps, called substitution urethroplasty, has become the gold standard procedure for anterior urethral strictures that are not amenable to excision and primary anastomosis. Oral mucosa harvested from the inner cheek (buccal mucosa) is an ideal material, and is most commonly used for substitution urethroplasty, and lingual mucosa harvested from the underside of the tongue has recently emerged as an alternative material with equivalent outcome...
June 10, 2017: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/28589564/editorial-comment-to-robot-assisted-laparoscopic-versus-open-partial-nephrectomy-in-patients-with-chronic-kidney-disease-a-propensity-score-matched-comparative-analysis-of-surgical-outcomes
#11
Andrea Minervini, Andrea Mari, Marco Carini
No abstract text is available yet for this article.
June 6, 2017: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/28589550/characterization-of-a-low-risk-cohort-of-grade-group-2-prostate-cancer-patients-results-from-the-shared-equal-access-regional-cancer-hospital-database
#12
Kathleen F McGinley, Xizi Sun, Lauren E Howard, William J Aronson, Martha K Terris, Christopher J Kane, Christopher L Amling, Matthew R Cooperberg, Stephen J Freedland
OBJECTIVES: To examine if there is a subset of men with grade group 2 prostate cancer who could be potential candidates for active surveillance. METHODS: We used the Shared Equal Access Regional Cancer Hospital database to identify 776 men undergoing radical prostatectomy from 2006 to 2015 with >8 biopsy cores obtained and complete information. We compared men who fulfilled low-risk disease criteria (clinical stage T1c/T2a; grade group 1; prostate-specific antigen ≤10 ng/mL) with the exception of grade group 2 versus men who met all three low-risk criteria...
June 6, 2017: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/28577511/therapies-for-castration-resistant-prostate-cancer-in-a-new-era-the-indication-of-vintage-hormonal-therapy-chemotherapy-and-the-new-medicines
#13
REVIEW
Atsushi Mizokami, Yoshifumi Kadono, Yasuhide Kitagawa, Kouji Izumi, Hiroyuki Konaka
When advanced prostate cancer recurred during hormonal therapy and became the castration-resistant prostate cancer, "vintage hormonal therapy," such as antiandrogen alternating therapy or estrogen-related hormonal therapy, was widely carried out in Japan until 2013. This vintage hormonal therapy controlled the progression of castration-resistant prostate cancer. When castration-resistant prostate cancer relapses during these therapies, chemotherapy using docetaxel has been carried out subsequently. Since new hormonal therapies using abiraterone acetate and enzalutamide, which improve the prognosis of castration-resistant prostate cancer, became available in Japan from 2014, therapeutic options for castration-resistant prostate cancer have increased...
June 3, 2017: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/28560809/editorial-comment-to-assessment-of-sexual-function-in-japanese-men-with-prostate-cancer-undergoing-permanent-brachytherapy-without-androgen-deprivation-therapy-analysis-from-the-japanese-prostate-cancer-outcome-study-of-permanent-iodine-125-seed-implantation
#14
https://www.readbyqxmd.com/read/28560739/predictive-value-of-different-prostate-specific-antigen-based-markers-in-men-with-baseline-total-prostate-specific-antigen-2-0-ng-ml
#15
Yuji Fujizuka, Kazuto Ito, Ryo Oki, Rie Suzuki, Yoshitaka Sekine, Hidekazu Koike, Hiroshi Matsui, Yasuhiro Shibata, Kazuhiro Suzuki
OBJECTIVES: To investigate the predictive value of various molecular forms of prostate-specific antigen in men with baseline prostate-specific antigen <2.0 ng/mL. METHODS: The case cohort comprised 150 men with a baseline prostate-specific antigen level <2.0 ng/mL, and who developed prostate cancer within 10 years. The control cohort was 300 baseline prostate-specific antigen- and age-adjusted men who did not develop prostate cancer. Serum prostate-specific antigen, free prostate-specific antigen, and [-2] proenzyme prostate-specific antigen were measured at baseline and last screening visit...
May 31, 2017: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/28556409/prevention-of-infectious-complications-after-prostate-biopsy-procedure
#16
REVIEW
Yoshikazu Togo, Shingo Yamamoto
Although febrile complications are rarely encountered after a prostate biopsy procedure, in recent years the number of cases of fatal infection after that have increased along with increases in resistant bacteria. The available biopsy approaches are transrectal and transperineal, with the transrectal approach primarily used. As the invasion path of the puncture needle differs between these approaches, pretreatment and the method of administration of preventive antimicrobial drugs should be separately considered for infection prevention...
May 27, 2017: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/28556438/anterior-compartment-descent-a-new-measure-in-the-assessment-of-urethral-hypermobility-in-women-with-urinary-incontinence
#17
Tamara Serdinšek, Igor But
OBJECTIVES: To introduce a new, simple, non-invasive test to quantify urethral hypermobility. METHODS: We reviewed data of women with urinary incontinence who were examined at the Department for General Gynaecology and Urogynaecology, Clinic for Gynaecology and Perinatology, Maribor, Slovenia, between October 2010 and March 2014. Patients' age, diagnosis, results of the Q-tip test and Pelvic Organ Prolapse Quantification measurements were collected. In addition, a new parameter was defined as anterior compartment descent, a midline distance between the external urethral meatus and maximum descent of the anterior vaginal wall when performed the Valsalva maneuver...
May 26, 2017: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/28556416/new-developments-in-chyluria-after-global-programs-to-eliminate-lymphatic-filariasis
#18
REVIEW
Anuruddha M Abeygunasekera, Kugadas Sutharshan, Balasingam Balagobi
Chyluria, commonly seen in south Asian countries, is mainly a manifestation of lymphatic filariasis as a result of infestation with Wuchereria bancrofti, although many other causes can contribute. Many patients can be effectively treated with dietary modifications and drug therapy. The most widely used drug is diethyl carbamazine. The recurrences are common after such treatment. Such patients would benefit from sclerotherapy to obliterate the lympatico-renal fistulae located mainly in the renal pelvicalyceal system...
May 26, 2017: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/28556400/real-time-three-dimensional-image-angle-rectification-to-improve-hand-eye-coordination-in-single-port-laparoendoscopic-surgery
#19
REVIEW
Soichiro Yoshida, Tsuneo Fukuyo, Kazutaka Saito, Kazunori Kihara, Yasuhisa Fujii
No abstract text is available yet for this article.
May 26, 2017: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/28556293/bone-scan-index-a-new-biomarker-of-bone-metastasis-in-patients-with-prostate-cancer
#20
REVIEW
Kenichi Nakajima, Lars Edenbrandt, Atsushi Mizokami
Bone scintigraphy is one of the first-line imaging modalities for the screening and follow up of bone metastasis in patients with prostate cancer. The amount (%) of bone metastasis can be calculated using a bone scan index thanks to recent advances in quantitative bone scintigraphy. Since an artificial neural network was applied for hot-spot characterization and quantitation, the bone scan index has become a simple, reproducible and practical means of quantifying bone metastasis. The bone scan index is presently considered as an imaging biomarker of bone metastasis...
May 26, 2017: International Journal of Urology: Official Journal of the Japanese Urological Association
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