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Academic Radiology

Yue Ma, Yang Cao, Aidi Liu, Lu Yin, Peng Han, Haijie Li, Xiaohua Zhang, Zhaoxiang Ye
RATIONALE AND OBJECTIVES: To evaluate the reliability of cone-beam breast computed tomography (CBBCT) in visual assessment of breast density referring to the fifth edition of the Breast Imaging Reporting and Data System compared to digital mammography. MATERIALS AND METHODS: Breast density assessments of 130 female patients were performed by five radiologists referring to the fifth edition of Breast Imaging Reporting and Data System atlas both on two-view mammograms and CBBCT images...
September 13, 2018: Academic Radiology
Marthony Robins, Jayashree Kalpathy-Cramer, Nancy A Obuchowski, Andrew Buckler, Maria Athelogou, Rudresh Jarecha, Nicholas Petrick, Aria Pezeshk, Berkman Sahiner, Ehsan Samei
RATIONALE AND OBJECTIVES: To evaluate a new approach to establish compliance of segmentation tools with the computed tomography volumetry profile of the Quantitative Imaging Biomarker Alliance (QIBA); and determine the statistical exchangeability between real and simulated lesions through an international challenge. MATERIALS AND METHODS: The study used an anthropomorphic phantom with 16 embedded physical lesions and 30 patient cases from the Reference Image Database to Evaluate Therapy Response with pathologically confirmed malignancies...
September 12, 2018: Academic Radiology
Dong Yue, Dong Rui Tong, Wang Fei Fei, Zhang Xiao Miao, Pang Hui Ting, Yu Tao, Luo Ya Hong
RATIONALE AND OBJECTIVES: To explore the imaging features of whole uterus volume CT perfusion (vCTP) and the influence factors of blood supply in cervical squamous carcinoma (CSC). MATERIALS AND METHODS: vCTP was performed on a 640-slice computed tomography system in 43 patients with CSC diagnosed by biopsy, and 24 cases of them underwent magnetic resonance imaging. The size of the tumor was measured on vCTP and magnetic resonance (MR) images. Perfusion parameters, including arterial blood flow (AF), blood volume, and permeability surface (PS), were measured by two radiologists, using interclass correlation coefficient to evaluate the interobserver reliability...
September 8, 2018: Academic Radiology
Minhaj S Khaja, William M Sherk, Paul G Gauger, David T Hughes, N Reed Dunnick, Janet E Bailey, Wael E Saad
The training paradigm of the interventional radiologist has quickly evolved with the approval of the integrated interventional radiology (IR) residency by the American Board of Medical Specialties and the Accreditation Council of Graduate Medical Education. Prior to appointment in an integrated IR program, a resident must complete a preliminary clinical year, which may be surgical, medical, or transitional. The unique procedural- and clinical-based skillset required of the IR resident is best aligned with a surgical preliminary year...
September 6, 2018: Academic Radiology
Chih-Wei Chen, Po-An Chen, Chiung-Chen Chou, Jui-Hsun Fu, Po-Chin Wang, Shuo-Hsiu Hsu, Ping-Hong Lai
RATIONALE AND OBJECTIVES: To evaluate image quality and radiation exposure when using the adaptive statistical iterative reconstruction-V (ASIR-V) algorithm for reconstructing craniocervical computed tomographic angiography images acquired at 100 kVp. MATERIALS AND METHODS: We randomly divided 121 patients into three groups: group A (conventional protocol), 120 kVp with filtered back projection; group B, 120 kVp with 50% ASIR-V; and group C, 100 kVp with 50% ASIR-V...
September 5, 2018: Academic Radiology
Nicholas J Tustison, Brian B Avants, Zixuan Lin, Xue Feng, Nicholas Cullen, Jaime F Mata, Lucia Flors, James C Gee, Talissa A Altes, John P Mugler Iii, Kun Qing
RATIONALE AND OBJECTIVES: We propose an automated segmentation pipeline based on deep learning for proton lung MRI segmentation and ventilation-based quantification which improves on our previously reported methodologies in terms of computational efficiency while demonstrating accuracy and robustness. The large data requirement for the proposed framework is made possible by a novel template-based data augmentation strategy. Supporting this work is the open-source ANTsRNet-a growing repository of well-known deep learning architectures first introduced here...
September 5, 2018: Academic Radiology
Melissa Min-Szu Yao, Bonnie N Joe, Edward A Sickles, Cindy S Lee
RATIONALE AND OBJECTIVES: The Breast Imaging-Reporting and Data System (BI-RADS) atlas defines category 5 assessments as appropriate only for lesions that are almost certainly cancer, with a positive predictive value (PPV) of ≥95%. This study aims to demonstrate the feasibility of classifying lesions at diagnostic breast imaging with sufficiently high PPV to merit category 5 assessments, and to identify those lesion descriptors that yield such a high PPV. MATERIALS AND METHODS: For this Health Insurance Portability and Accountability Act compliant and IRB exempt study, we reviewed diagnostic breast imaging examinations (mammography and/or ultrasound) assessed as highly suggestive of malignancy (BI-RADS category 5)...
September 5, 2018: Academic Radiology
Zixing Huang, Mou Li, Du He, Yi Wei, Haopeng Yu, Yi Wang, Fang Yuan, Bin Song
OBJECTIVE: To retrospectively assess the diagnostic performance of texture analysis and characteristics of CT images for the discrimination of pancreatic lymphoma (PL) from pancreatic adenocarcinoma (PA). METHODS: Fifteen patients with pathologically proved PL were compared with 30 age-matched controls with PA in a 1:2 ratio. Patients underwent a CT scan with three phases including the precontrast phase, the arterial phase, and the portal vein phase. The regions of interest of PA and PL were drawn and analyzed to derive texture parameters with MaZda software...
September 4, 2018: Academic Radiology
Richard B Gunderman, Abdul R S Aasar
No abstract text is available yet for this article.
September 3, 2018: Academic Radiology
Richard B Gunderman, Parth Patel
No abstract text is available yet for this article.
September 3, 2018: Academic Radiology
Logan Hubbard, Shant Malkasian, Yixiao Zhao, Pablo Abbona, Sabee Molloi
RATIONALE AND OBJECTIVES: The accuracy of coronary computed tomography (CT) angiography depends upon the degree of coronary enhancement as compared to the background noise. Unfortunately, coronary contrast-to-noise ratio (CNR) optimization is difficult on a patient-specific basis. Hence, the objective of this study was to validate a new combined diluted test bolus and CT angiography protocol for improved coronary enhancement and CNR. MATERIALS AND METHODS: The combined diluted test bolus and CT angiography protocol was validated in six swine (28...
August 29, 2018: Academic Radiology
Chunhai Li, Bo Liu, Hong Meng, Guangbin Wang, Cuiyan Wang, Haipeng Jia
RATIONALE AND OBJECTIVES: To prospectively assess effect of dual-source radiofrequency (RF) transmission on left ventricular (LV) measurements and measurements reproducibility at 3.0 T MR using balanced steady-state free precession (b-SSFP) cine imaging, compared to the conventional single-source RF transmission reference approach. MATERIALS AND METHODS: Cardiac b-SSFP cine imaging was performed in 19 subjects at 3.0 T MR equipped with dual-source RF transmission...
August 29, 2018: Academic Radiology
Seyedamir Tavakoli Taba, Patrycja Baran, Sarah Lewis, Robert Heard, Serena Pacile, Yakov I Nesterets, Sherry C Mayo, Christian Dullin, Diego Dreossi, Fulvia Arfelli, Darren Thompson, Mikkaela McCormack, Maram Alakhras, Francesco Brun, Maurizio Pinamonti, Carolyn Nickson, Chris Hall, Fabrizio Zanconati, Darren Lockie, Harry M Quiney, Giuliana Tromba, Timur E Gureyev, Patrick C Brennan
RATIONALE AND OBJECTIVES: This study employs clinical/radiological evaluation in establishing the optimum imaging conditions for breast cancer imaging using the X-ray propagation-based phase-contrast tomography. MATERIALS AND METHODS: Two series of experiments were conducted and in total 161 synchrotron-based computed tomography (CT) reconstructions of one breast mastectomy specimen were produced at different imaging conditions. Imaging factors include sample-to-detector distance, X-ray energy, CT reconstruction method, phase retrieval algorithm applied to the CT projection images and maximum intensity projection...
August 25, 2018: Academic Radiology
Youichi Machida, Akiko Shimauchi, Takao Igarashi, Eisuke Fukuma
RATIONALE AND OBJECTIVES: To retrospectively evaluate findings on serial magnetic resonance imaging (MRI) after cryoablation for breast cancer lesions without subsequent surgical resection. MATERIALS AND METHODS: This study was approved by the Institutional Review Board and the requirement to obtain informed consent waived. Ductal carcinoma in situ or invasive carcinoma ≤15 mm, nuclear grade 1 or 2, estrogen receptor positive/human epidermal growth factor 2 negative without lymph node metastasis were treated with cryoablation without subsequent excision...
August 24, 2018: Academic Radiology
Heike Preibsch, Johannes Beckmann, Johannes Pawlowski, Christopher Kloth, Markus Hahn, Annette Staebler, Beate M Wietek, Konstantin Nikolaou, Benjamin Wiesinger
RATIONALE AND OBJECTIVES: Ductal carcinoma in situ (DCIS) hinders imaging detection due to multifocal appearance and discontinuous growth. Preoperative determination of its extent is therefore challenging. Aim of this study was to investigate the additional benefit of breast magnetic resonance imaging (MRI) to mammography (MG) in the diagnosis of DCIS according to size and grading. MATERIALS AND METHODS: Retrospective analysis of 295 patients with biopsy-proven, pure DCIS...
August 24, 2018: Academic Radiology
Silvia Gigli, Maria Ida Amabile, Emanuele David, Alessandro De Luca, Cristina Grippo, Lucia Manganaro, Massimo Monti, Laura Ballesio
RATIONALE AND OBJECTIVES: The aim of this study was to retrospectly investigate the association between different breast cancer (BC) immunohistochemical subtypes and morphological and semiquantitative kinetic analysis on breast magnetic resonance imaging (MRI) performed before surgery treatment. Specifically we aimed to assess MRI features of triple-negative breast cancer (TNBC) compared to the other BC subtypes (nTNBC). MATERIALS AND METHODS: Patients undergone to breast MRI and then diagnosed with BC by core-needle biopsy were included...
August 23, 2018: Academic Radiology
Charbel Saade, Ahmad Ammous, Alain S Abi-Ghanem, Frederik Giesel, Karl Asmar
RATIONALE AND OBJECTIVES: To investigate radiation dose reduction during whole body fluorodeoxyglucose (18 F-FDG) positron emission tomographic (PET)/computed tomography (CT) by employing weight-based protocols. MATERIALS AND METHODS: One thousand and twenty-eight patients were referred for 18 F-FDG PET/CT study with one of two protocols: conventional protocol I; 120 kVp, 120 mAs, 0.5 second rotation time, pitch 0.8 mm/rot across all body weights; four-tier body weight protocol II all used 140 kVp, 0...
August 22, 2018: Academic Radiology
Tae-Hoon Kim, Chang-Won Jeong, Hong Young Jun, Youe Ree Kim, Ju Young Kim, Young Hwan Lee, Kwon-Ha Yoon
RATIONALE AND OBJECTIVES: The roles of iron stores in nonalcoholic fatty liver disease have not yet been clearly identified, and it is lack of uniform criteria and a standardized study design for assessing the liver iron content (LIC) in nonalcoholic steatohepatitis (NASH). This study was to compare LICs in biopsy-proven simple steatosis (SS) and NASH based on T2 ⁎ -relaxometry. MATERIAL AND METHODS: A total of 32 subjects divided to three groups, consisting of 10 healthy controls, 12 SS and 10 NASH...
August 22, 2018: Academic Radiology
Ryan W Woods, Melissa S Camp, Nicholas J Durr, Susan C Harvey
Invasive breast cancer is a common disease, and the most common initial site of metastatic disease are the axillary lymph nodes. As the standard of care shifts towards less invasive surgery in the axilla for patients with invasive breast cancer, techniques have been developed for axillary node localization that allow targeted dissection of specific lymph nodes without requiring full axillary lymph node dissection. Many of these techniques have been adapted from technologies developed for localization of lesions within the breast and include marker clip placement with intraoperative ultrasound, carbon-suspension liquids, localization wires, radioactive seeds, magnetic seeds, radar reflectors, and radiofrequency identification devices...
August 22, 2018: Academic Radiology
Ashish P Wasnik
No abstract text is available yet for this article.
August 16, 2018: Academic Radiology
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