Qiyuan Shan, Wei Yu, Qiongfang Xu, Ruina Liu, Shuye Ying, Jie Dong, Yini Bao, Qiang Lyu, Changcheng Shi, Junjie Xia, Jing Tang, Haodan Kuang, Kuilong Wang, Gang Tian, Gang Cao
BACKGROUND: Alkaloids have attracted enduring interest worldwide due to their remarkable therapeutic effects, including analgesic, anti-inflammatory, and anti-tumor properties, thus offering a rich source for lead compound design and new drug discovery. However, some of these alkaloids possess intrinsic toxicity. Processing (Paozhi) is a pre-treatment step before the application of herbal medicines in traditional Chinese medicine (TCM) clinics, which has been employed for centuries to mitigate the toxicity of alkaloid-rich TCMs...
April 17, 2024: Phytomedicine