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Cancer Control: Journal of the Moffitt Cancer Center

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https://www.readbyqxmd.com/read/27842338/highlighting-health-disparities-in-racial-and-ethnic-minorities-and-other-underserved-populations
#1
Clement K Gwede, Gwendolyn P Quinn, B Lee Green
No abstract text is available yet for this article.
October 2016: Cancer Control: Journal of the Moffitt Cancer Center
https://www.readbyqxmd.com/read/27842337/better-cancer-treatment-for-all
#2
Lodovico Balducci
No abstract text is available yet for this article.
October 2016: Cancer Control: Journal of the Moffitt Cancer Center
https://www.readbyqxmd.com/read/27842336/a-single-institution-study-of-demographics-and-outcomes-of-adult-patients-with-multiple-cancers
#3
Thanh P Ho, Nathan R Foster, Aminah Jatoi
BACKGROUND: Few studies have described the demographics and outcomes in patients with multiple cancers. METHODS: We reviewed the health records of patients with at least 3 invasive solid-tumor malignancies (lung, colorectal, pancreatic, prostate, breast, or ovarian) diagnosed between 1995 and 2014 at our institution. RESULTS: A total of 163 patients were identified. The median age at first cancer diagnosis was 61 years. Sixteen (10%) had a family history of cancer, and 7 (4%) had a cancer-predisposing syndrome...
October 2016: Cancer Control: Journal of the Moffitt Cancer Center
https://www.readbyqxmd.com/read/27842335/systematic-review-and-case-series-report-of-acinar-cell-carcinoma-of-the-pancreas
#4
Evan S Glazer, Kevin G Neill, Jessica M Frakes, Domenico Coppola, Pamela J Hodul, Sara E Hoffe, Jose M Pimiento, Gregory M Springett, Mokenge P Malafa
BACKGROUND: Acinar cell carcinoma of the pancreas is a rare malignancy representing less than 1% of all pancreatic malignancies. METHODS: We report on a case series of 21 patients with acinar cell carcinoma of the pancreas treated at a high-volume quaternary center. A systematic review of the medical literature was performed that described typical therapeutic management approaches for acinar cell carcinoma of the pancreas and reported on disease control and survival rates...
October 2016: Cancer Control: Journal of the Moffitt Cancer Center
https://www.readbyqxmd.com/read/27842334/human-metapneumovirus-infection-in-immunocompromised-patients
#5
Sharmeen Samuel, Sowmya Nanjappa, Christopher D Cooper, John N Greene
Human metapneumovirus (HMPV) is a pathogen associated with respiratory tract infection and is related to avian pneumovirus. Typically, children, the elderly, and those who are immunocompromised are the most susceptible to HMPV infection; however, the virus can infect persons of all ages. In otherwise healthy individuals, HMPV infection is generally self-limiting, but immunocompromised individuals can develop fatal complications. We present a case series of 3 severely immunocompromised patients who were infected with HMPV and describe their clinical course...
October 2016: Cancer Control: Journal of the Moffitt Cancer Center
https://www.readbyqxmd.com/read/27842333/tobacco-related-health-disparities-across-the-cancer-care-continuum
#6
Vani Nath Simmons, Barbara Pineiro, Monica Webb Hooper, Jhanelle E Gray, Thomas H Brandon
BACKGROUND: Use of tobacco is the leading preventable cause of death in the United States. Racial/ethnic minorities and individuals of low socioeconomic status disproportionately experience tobacco-related disease and illness. Unique challenges and circumstances exist at each point in the cancer care continuum that may contribute to the greater cancer burden experienced by these groups. METHODS: We reviewed tobacco-related disparities from cancer prevention to cancer survivorship...
October 2016: Cancer Control: Journal of the Moffitt Cancer Center
https://www.readbyqxmd.com/read/27842332/disparities-in-adolescents-and-young-adults-with-cancer
#7
Leidy L Isenalumhe, Olivia Fridgen, Lynda K Beaupin, Gwendolyn P Quinn, Damon R Reed
BACKGROUND: Cancer care for adolescents and young adults (AYAs) focuses on the care of patients aged 15 to 39 years. Historically, this group has favorable outcomes based on a preponderance of diagnoses such as thyroid cancers and Hodgkin lymphoma. Improvements in outcomes among the AYA population have lagged behind compared with younger and older populations. METHODS: We discuss and review recent progress in AYA patient care and highlight remaining disparities that exist, including financial disadvantages, need for fertility care, limited clinical trial availability, and other areas of evolving AYA-focused research...
October 2016: Cancer Control: Journal of the Moffitt Cancer Center
https://www.readbyqxmd.com/read/27842331/chemoprevention-in-african-american-men-with-prostate-cancer
#8
Nagi B Kumar, Julio M Pow-Sang, Philippe E Spiess, Jong Y Park, Ganna Chornokur, Andrew R Leone, Catherine M Phelan
BACKGROUND: Recommendations for cancer screening are uncertain for the early detection or prevention of prostate cancer in African American men. Thus, chemoprevention strategies are needed to specifically target African American men. METHODS: The evidence was examined on the biological etiology of disparities in African Americans related to prostate cancer. Possible chemopreventive agents and biomarkers critical to prostate cancer in African American men were also studied...
October 2016: Cancer Control: Journal of the Moffitt Cancer Center
https://www.readbyqxmd.com/read/27842330/disparities-in-penile-cancer
#9
Pranav Sharma, Kamran Zargar-Shoshtari, Curtis A Pettaway, Matthew B Schabath, Anna R Giuliano, Philippe E Spiess
BACKGROUND: Although penile cancer is a rare malignancy in developed nations, racial and socioeconomic differences exist in the incidence of the disease and its associated survival-related outcomes. METHODS: A search of the literature was performed for research published between the years 1990 and 2015. Case reports and non-English-language articles were excluded, instead focusing specifically on large, population-based studies. RESULTS: The incidence of penile cancer is higher in Hispanic and African American men compared with whites and Asians...
October 2016: Cancer Control: Journal of the Moffitt Cancer Center
https://www.readbyqxmd.com/read/27842329/geographical-factors-associated-with-health-disparities-in-prostate-cancer
#10
Scott M Gilbert, Julio M Pow-Sang, Hong Xiao
BACKGROUND: Treatment variation in prostate cancer is common, and it is driven by clinical and clinician factors, patient preferences, availability of resources, and access to physicians and treating facilities. Most research on treatment disparities in men with prostate cancer has focused on race and socioeconomic factors. However, the geography of disparities - capturing racial and socioeconomic differences based on where patients live - can provide insight into barriers to care and help identify outlier areas in which access to care, health resources, or both are more pronounced...
October 2016: Cancer Control: Journal of the Moffitt Cancer Center
https://www.readbyqxmd.com/read/27842328/determinants-of-treatment-delays-among-underserved-hispanics-with-lung-and-head-and-neck-cancers
#11
Evelinn A Borrayo, Katie L Scott, Ava R Drennen, Tiare MacDonald, Jennifer Nguyen
BACKGROUND: Evidence is lacking to explain the reasons why treatment is delayed among disadvantaged Hispanic patients diagnosed with lung and head and neck cancers. Data indicate that treatment delays beyond 46 days increase the risk of death for individuals with these cancers. METHODS: A mixed-methods design was used to explore determinants of treatment delays by analyzing data from the medical records of 40 Hispanic patients and data from interviews with 29 Hispanic patients, caregivers, health care professionals, and patient navigators from a safety-net hospital...
October 2016: Cancer Control: Journal of the Moffitt Cancer Center
https://www.readbyqxmd.com/read/27842327/construction-and-validation-of-a-multi-institutional-tissue-microarray-of-invasive-ductal-carcinoma-from-racially-and-ethnically-diverse-populations
#12
Edward Seijo, Diana Lima, Egiebade Iriabho, Jonas Almeida, Jesus Monico, Margarita Echeverri, Sylvia Gutierrez, Idhaliz Flores, Ji-Hyun Lee, Kate Fisher, William E Grizzle, Gabriel L Sica, Charles Butler, Chindo Hicks, Cathy D Meade, Stephen Olufemi Sodeke, Krzysztof Moroz, Domenico Coppola, Teresita Munoz-Antonia
BACKGROUND: The scarcity of tissues from racial and ethnic minorities at biobanks poses a scientific constraint to research addressing health disparities in minority populations. METHODS: To address this gap, the Minority Biospecimen/Biobanking Geographic Management Program for region 3 (BMaP-3) established a working infrastructure for a "biobanking" hub in the southeastern United States and Puerto Rico. Herein we describe the steps taken to build this infrastructure, evaluate the feasibility of collecting formalin-fixed, paraffin-embedded tissue blocks and associated data from a single cancer type (breast), and create a web-based database and tissue microarrays (TMAs)...
October 2016: Cancer Control: Journal of the Moffitt Cancer Center
https://www.readbyqxmd.com/read/27842326/clinical-considerations-of-risk-incidence-and-outcomes-of-breast-cancer-in-sexual-minorities
#13
Anne E Mattingly, John V Kiluk, M Catherine Lee
BACKGROUND: Breast cancer is a leading cause of cancer-related mortality in women. Limited research exists on the impact of sexual orientation on overall risk of and mortality from breast cancer. We sought to summarize the medical literature on breast cancer in sexual minority women and identify possible disparities in this population. METHODS: A comprehensive literature search was conducted for English-language studies in peer-reviewed medical journals that referenced breast cancer and sexual minority, lesbian, bisexual, or transgender individuals...
October 2016: Cancer Control: Journal of the Moffitt Cancer Center
https://www.readbyqxmd.com/read/27842325/genomic-disparities-in-breast-cancer-among-latinas
#14
Filipa Lynce, Kristi D Graves, Lina Jandorf, Charite Ricker, Eida Castro, Laura Moreno, Bianca Augusto, Laura Fejerman, Susan T Vadaparampil
BACKGROUND: Breast cancer is the most common cancer diagnosed among Latinas in the United States and the leading cause of cancer-related death among this population. Latinas tend to be diagnosed at a later stage and have worse prognostic features than their non-Hispanic white counterparts. Genetic and genomic factors may contribute to observed breast cancer health disparities in Latinas. METHODS: We provide a landscape of our current understanding and the existing gaps that need to be filled across the cancer prevention and control continuum...
October 2016: Cancer Control: Journal of the Moffitt Cancer Center
https://www.readbyqxmd.com/read/27842324/black-heterogeneity-in-cancer-mortality-us-blacks-haitians-and-jamaicans
#15
Paulo S Pinheiro, Karen E Callahan, Camille Ragin, Robert W Hage, Tara Hylton, Erin N Kobetz
INTRODUCTION: The quantitative intraracial burden of cancer incidence, survival and mortality within black populations in the United States is virtually unknown. METHODS: We computed cancer mortality rates of US- and Caribbean-born residents of Florida, specifically focusing on black populations (United States, Haiti, Jamaica) and compared them using age-adjusted mortality ratios obtained from Poisson regression models. We compared the mortality of Haitians and Jamaicans residing in Florida to populations in their countries of origin using Globocan...
October 2016: Cancer Control: Journal of the Moffitt Cancer Center
https://www.readbyqxmd.com/read/27842323/racial-and-ethnic-differences-in-the-epidemiology-and-genomics-of-lung-cancer
#16
Matthew B Schabath, Douglas Cress, Teresita Munoz-Antonia
BACKGROUND: Lung cancer is the most common cancer in the world. In addition to the geographical and sex-specific differences in the incidence, mortality, and survival rates of lung cancer, growing evidence suggests that racial and ethnic differences exist. METHODS: We reviewed published data related to racial and ethnic differences in lung cancer. RESULTS: Current knowledge and substantive findings related to racial and ethnic differences in lung cancer were summarized, focusing on incidence, mortality, survival, cigarette smoking, prevention and early detection, and genomics...
October 2016: Cancer Control: Journal of the Moffitt Cancer Center
https://www.readbyqxmd.com/read/27842322/barriers-to-clinical-trial-enrollment-in-racial-and-ethnic-minority-patients-with-cancer
#17
Lauren M Hamel, Louis A Penner, Terrance L Albrecht, Elisabeth Heath, Clement K Gwede, Susan Eggly
BACKGROUND: Clinical trials that study cancer are essential for testing the safety and effectiveness of promising treatments, but most people with cancer never enroll in a clinical trial - a challenge exemplified in racial and ethnic minorities. Underenrollment of racial and ethnic minorities reduces the generalizability of research findings and represents a disparity in access to high-quality health care. METHODS: Using a multilevel model as a framework, potential barriers to trial enrollment of racial and ethnic minorities were identified at system, individual, and interpersonal levels...
October 2016: Cancer Control: Journal of the Moffitt Cancer Center
https://www.readbyqxmd.com/read/27842052/best-practices-in-treatment-selection-for-patients-with-advanced-nsclc
#18
Mark A Socinski, Nathan A Pennell
Worldwide, lung cancer is the most prevalent form of cancer, and its non-small-cell subtype constitutes up to 85% of cases. Overall, lung cancer is the most common cause of cancer-related death in the United States for both sexes, and its 5-year survival rate is 17%. It is a heterogeneous disease characterized by a variety of biomarkers and differing histologies. Non-small-cell lung cancer may be squamous or nonsquamous in nature and fueled by a number of oncodrivers. Obtaining sufficient tissue during biopsy to perform thorough biomarker testing is a challenge but essential for the modern, targeted therapeutic environment...
October 2016: Cancer Control: Journal of the Moffitt Cancer Center
https://www.readbyqxmd.com/read/27556672/hypofractionated-stereotactic-radiotherapy-for-auditory-canal-or-middle-ear-cancer
#19
Taro Murai, Shin-Etsu Kamata, Kengo Sato, Kouki Miura, Mitsuhiro Inoue, Naoki Yokota, Seiji Ohta, Michio Iwabuchi, Hiromitsu Iwata, Yuta Shibamoto
BACKGROUND: Stereotactic radiotherapy (SRT) may represent a new treatment option for individuals with auditory canal or middle ear cancer. METHODS: Study participants with pathologically proven ear cancer were treated with SRT (35 Gy for 3 fractions or 40 Gy for 5 fractions) as first-line therapy. When local tumor recurrence developed following SRT, subtotal temporal bone resection and postoperative chemoradiotherapy were performed as salvage treatment. Boluses were used for the initial 14 study patients...
July 2016: Cancer Control: Journal of the Moffitt Cancer Center
https://www.readbyqxmd.com/read/27556671/feasibility-preliminary-efficacy-and-lessons-learned-from-a-garden-based-lifestyle-intervention-for-cancer-survivors
#20
Colleen K Spees, Emily B Hill, Elizabeth M Grainger, Jackie L Buell, Susan E White, Matthew D Kleinhenz, Steven K Clinton
BACKGROUND: Cancer survivors remain at increased risk for secondary malignancies, comorbidities, and all-cause mortality. Lifestyle behaviors, such as diet and physical activity, are strongly linked to a decreased risk of chronic disease and improved health outcomes, yet a paucity of research has been conducted in this vulnerable population. METHODS: Adult cancer survivors were recruited to participate in Growing Hope, an experimental single-group study designed to assess the feasibility and efficacy of a theory-driven and evidence-based intervention...
July 2016: Cancer Control: Journal of the Moffitt Cancer Center
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