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Endocrine

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https://www.readbyqxmd.com/read/28429281/impact-of-thyroid-disease-on-testicular-function
#1
REVIEW
Sandro La Vignera, Roberto Vita, Rosita A Condorelli, Laura M Mongioì, Silvia Presti, Salvatore Benvenga, Aldo E Calogero
INTRODUCTION: Testis was considered unresponsive to thyroid hormone for a long time. However, like in animals, the presence of thyroid hormone receptors in different testicular cell types was demonstrated also in humans. Accordingly, thyrotoxicosis and hypothyroidism have remarkable effects on testicular function and more extensively on fertility. REVIEW: Thyrotoxicosis and hypothyroidism are associated with changes affecting the endocrine, sexual, or reproductive functions...
April 20, 2017: Endocrine
https://www.readbyqxmd.com/read/28424969/values-and-limitations-of-the-comparing-thyroid-radiofrequency-and-microwave-ablation-using-propensity-score
#2
LETTER
Hye Sun Park, Jung Hwan Baek, Auh Whan Park
No abstract text is available yet for this article.
April 19, 2017: Endocrine
https://www.readbyqxmd.com/read/28421418/lower-urinary-tract-symptoms-luts-in-males-with-type-2-diabetes-recently-treated-with-sglt2-inhibitors-overlooked-and-overwhelming-a-retrospective-case-series
#3
LETTER
Nino Cristiano Chilelli, Giuseppe Bax, Giulio Bonaldo, Eugenio Ragazzi, Massimo Iafrate, Filiberto Zattoni, Federico Bellavere, Annunziata Lapolla
No abstract text is available yet for this article.
April 18, 2017: Endocrine
https://www.readbyqxmd.com/read/28417314/prognostic-factors-for-gastroenteropancreatic-neuroendocrine-neoplasms-gep-nens-what-s-better
#4
EDITORIAL
Massimo Milione
No abstract text is available yet for this article.
April 17, 2017: Endocrine
https://www.readbyqxmd.com/read/28417313/impact-of-season-and-different-vitamin-d-thresholds-on-prevalence-of-vitamin-d-deficiency-in-epidemiological-cohorts-a-note-of-caution
#5
Sara Schramm, Harald Lahner, Karl-Heinz Jöckel, Raimund Erbel, Dagmar Führer, Susanne Moebus
PURPOSE: We investigated the impact of different cut-offs on the prevalence of 25-hydroxyvitamin D [25-(OH)D] deficiency. METHODS: We used baseline data of 4149 participants (45-75 years, 50% women) of the population-based Heinz Nixdorf Recall study. Serum 25-(OH)D was measured with the Roche Cobas assay. Quartiles (p25, p50, and p75) were calculated. Data were stratified by months, sex, and age. According to the recommendations of 'Dachverband Osteologie', Endocrine Society and National Institute of Health we used 25-(OH)D thresholds of 12, 20, and 30 ng/ml to estimate vitamin D deficiency...
April 17, 2017: Endocrine
https://www.readbyqxmd.com/read/28417312/the-need-for-national-registries-for-rare-endocrine-tumor-syndromes
#6
EDITORIAL
Rachel S van Leeuwaarde, Wouter W de Herder, Gerlof D Valk
No abstract text is available yet for this article.
April 17, 2017: Endocrine
https://www.readbyqxmd.com/read/28405881/accuracy-of-recommended-sampling-and-assay-methods-for-the-determination-of-plasma-free-and-urinary-fractionated-metanephrines-in-the-diagnosis-of-pheochromocytoma-and-paraganglioma-a-systematic-review
#7
Roland Därr, Matthias Kuhn, Christoph Bode, Stefan R Bornstein, Karel Pacak, Jacques W M Lenders, Graeme Eisenhofer
PURPOSE: To determine the accuracy of biochemical tests for the diagnosis of pheochromocytoma and paraganglioma. METHODS: A search of the PubMed database was conducted for English-language articles published between October 1958 and December 2016 on the biochemical diagnosis of pheochromocytoma and paraganglioma using immunoassay methods or high-performance liquid chromatography with coulometric/electrochemical or tandem mass spectrometric detection for measurement of fractionated metanephrines in 24-h urine collections or plasma-free metanephrines obtained under seated or supine blood sampling conditions...
April 12, 2017: Endocrine
https://www.readbyqxmd.com/read/28405880/steap4-expression-in-human-islets-is-associated-with-differences-in-body-mass-index-sex-hba1c-and-inflammation
#8
Hannah M Gordon, Neil Majithia, Patrick E MacDonald, Jocelyn E Manning Fox, Poonam R Sharma, Frances L Byrne, Kyle L Hoehn, Carmella Evans-Molina, Linda Langman, Kenneth L Brayman, Craig S Nunemaker
OBJECTIVE: STEAP4 (six-transmembrane epithelial antigen of the prostate 4) is a metalloreductase that has been shown previously to protect cells from inflammatory damage. Genetic variants in STEAP4 have been associated with numerous metabolic disorders related to obesity, including putative defects in the acute insulin response to glucose in type 2 diabetes. PURPOSE: We examined whether obesity and/or type 2 diabetes altered STEAP4 expression in human pancreatic islets...
April 12, 2017: Endocrine
https://www.readbyqxmd.com/read/28405879/histopathological-and-genetic-characterization-of-aldosterone-producing-adenomas-with-concurrent-subclinical-cortisol-hypersecretion-a-case-series
#9
Francesco Fallo, Isabella Castellano, Celso E Gomez-Sanchez, Yara Rhayem, Catia Pilon, Valentina Vicennati, Donatella Santini, Valeria Maffeis, Ambrogio Fassina, Paolo Mulatero, Felix Beuschlein, Martin Reincke
PURPOSE: Aldosterone-producing adenomas with concurrent subclinical cortisol hypersecretion are reported in an increasing number of patients. Five aldosterone-producing adenomas from patients with primary aldosteronism and subclinical hypercortisolism were examined. THE AIMS OF OUR STUDY WERE: (1) to analyze pathological features and immunohistochemical expression of CYP11B1 (11β-hydroxylase) and CYP11B2 (aldosterone synthase) in these tumors; (2) to investigate somatic mutations involved in adrenal steroid hypersecretion and/or tumor growth...
April 12, 2017: Endocrine
https://www.readbyqxmd.com/read/28401444/fixed-ratio-combinations-of-glucagon-like-peptide-1-receptor-agonists-with-basal-insulin-a-systematic-review-and-meta-analysis
#10
Paraskevi Liakopoulou, Aris Liakos, Despoina Vasilakou, Eleni Athanasiadou, Eleni Bekiari, Kyriakos Kazakos, Apostolos Tsapas
PURPOSE: Basal insulin controls primarily fasting plasma glucose but causes hypoglycaemia and weight gain, whilst glucagon like peptide 1 receptor agonists induce weight loss without increasing risk for hypoglycaemia. We conducted a systematic review and meta-analysis of randomised controlled trials to investigate the efficacy and safety of fixed ratio combinations of basal insulin with glucagon like peptide 1 receptor agonists. METHODS: We searched Medline, Embase, and the Cochrane Library as well as conference abstracts up to December 2016...
April 12, 2017: Endocrine
https://www.readbyqxmd.com/read/28401443/prevalence-of-hypophysitis-in-a-cohort-of-patients-with-metastatic-melanoma-and-prostate-cancer-treated-with-ipilimumab
#11
Lucia Brilli, Riccardo Danielli, Cristina Ciuoli, Luana Calabrò, Anna Maria Di Giacomo, Alfonso Cerase, Patrizia Paffetti, Fausta Sestini, Brunetta Porcelli, Michele Maio, Furio Pacini
OBJECTIVE: Ipilimumab is a human monoclonal antibody directed against cytotoxic T-lymphocyte antigen-4, that has been shown to significantly improve survival in patients with metastatic melanoma. Blocking cytotoxic T-lymphocyte antigen-4 elicits T cell activation, proliferation and anti-tumor response, but can also trigger immune-related adverse events. Among immune-related endocrinopathies, hypophysitis represents the most frequent, with an incidence up to 17% in patients treated with ipilimumab...
April 12, 2017: Endocrine
https://www.readbyqxmd.com/read/28401442/erratum-to-chronic-hyperglycemia-affects-bone-metabolism-in-adult-zebrafish-scale-model
#12
Marta Carnovali, Livio Luzi, Giuseppe Banfi, Massimo Mariotti
No abstract text is available yet for this article.
April 11, 2017: Endocrine
https://www.readbyqxmd.com/read/28390011/association-between-lifestyle-and-anthropometric-parameters-and-thyroid-nodule-features
#13
Grigorios Panagiotou, Despina Komninou, Panagiotis Anagnostis, George Linardos, Eleni Karoglou, Maria Somali, Leonidas Duntas, Marina Kita, Konstantinos Tziomalos, Kalliopi Pazaitou-Panayiotou
PURPOSE: Thyroid nodularity has been associated with obesity, but data regarding associations of body composition parameters with specific ultrasound features of thyroid nodules are lacking. The aim of the present study was to assess associations between thyroid nodule ultrasound characteristics, lifestyle, and anthropometric parameters. SUBJECTS AND METHODS: This was a cross-sectional study in the general apparently healthy population of Northern Greece. Thyroid ultrasound data together with medical history, demographic, and anthropometric characteristics were individually recorded...
April 8, 2017: Endocrine
https://www.readbyqxmd.com/read/28390010/vitamin-d-supplementation-in-the-prevention-and-management-of-major-chronic-diseases-not-related-to-mineral-homeostasis-in-adults-research-for-evidence-and-a-scientific-statement-from-the-european-society-for-clinical-and-economic-aspects-of-osteoporosis-and
#14
Luisella Cianferotti, Francesco Bertoldo, Heike A Bischoff-Ferrari, Olivier Bruyere, Cyrus Cooper, Maurizio Cutolo, John A Kanis, Jean-Marc Kaufman, Jean-Yves Reginster, Rene Rizzoli, Maria Luisa Brandi
INTRODUCTION: Optimal vitamin D status promotes skeletal health and is recommended with specific treatment in individuals at high risk for fragility fractures. A growing body of literature has provided indirect and some direct evidence for possible extraskeletal vitamin D-related effects. PURPOSE AND METHODS: Members of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis have reviewed the main evidence for possible proven benefits of vitamin D supplementation in adults at risk of or with overt chronic extra-skeletal diseases, providing recommendations and guidelines for future studies in this field...
April 7, 2017: Endocrine
https://www.readbyqxmd.com/read/28390009/mutations-in-proteasome-related-genes-are-associated-with-thyroid-hemiagenesis
#15
Bartlomiej Budny, Ewelina Szczepanek-Parulska, Tomasz Zemojtel, Witold Szaflarski, Malgorzata Rydzanicz, Joanna Wesoly, Luiza Handschuh, Kosma Wolinski, Katarzyna Piatek, Marek Niedziela, Katarzyna Ziemnicka, Marek Figlerowicz, Maciej Zabel, Marek Ruchala
PURPOSE: Human thyroid development is a complex and still unexplained process. Thyroid hemiagenesis is a congenital anomaly, where one of the thyroid lobes fails to develop. In the majority of patients with thyroid hemiagenesis, the genetic background remains unknown. The aim of the study was to search for novel genetic contributors to the etiology of thyroid hemiagenesis. METHODS: A cohort of 34 sporadic patients diagnosed with thyroid hemiagenesis and one three-generation family were subjected to comprehensive genomic examination...
April 7, 2017: Endocrine
https://www.readbyqxmd.com/read/28386723/effects-of-sample-storage-and-diluents-in-the-reliability-of-thyroglobulin-measurement-in-the-washout-of-fine-needle-aspirates
#16
Fanny Piotrkowski-Viale, Adriana Reyes, Alicia Dios, Fabian Pitoia, Alicia Lowenstein, Patricia Glikman
OBJECTIVE: To evaluate two variables affecting Thyroglobulin stability in the washout of fine needle aspiration biopsies of thyroid nodules and metastatic lymph nodes. MATERIALS AND METHODS: Thyroglobulin stability after storage at -20 °C up to 14 days was studied in washout performed with normal saline solution and further dilutions with normal saline solution from five metastatic thyroid nodes and six benign thyroid nodules. We also studied thyroglobulin stability in diluents compared with normal saline solution: 4% bovine serum albumin in normal saline solution and diluents free from thyroglobulin or Calcitonin or parathyroid hormone in paired and simultaneous thyroglobulin measurements of washout dilutions from 5/6 benign thyroid nodules and 2/5 metastatic lymph nodes...
April 6, 2017: Endocrine
https://www.readbyqxmd.com/read/28386722/does-pasireotide-directly-modulate-skeletal-muscle-metabolism
#17
EDITORIAL
Federico Gatto, Tullio Florio
No abstract text is available yet for this article.
April 6, 2017: Endocrine
https://www.readbyqxmd.com/read/28374151/an-update-on-the-potential-role-of-c-peptide-in-diabetes-and-osteoporosis
#18
Arturo Pujia, Carmine Gazzaruso, Tiziana Montalcini
PURPOSE: C-peptide secretion is deficient or absent in type 1 diabetes mellitus. It is well accepted that insulin replacement therapy cannot prevent the development of long-term diabetes-related complications, which can often be disabling or even life-threatening. Several cross-sectional investigations have suggested that residual C-peptide production in patients with type 1 diabetes mellitus would help prevent a number of complications. In animal models of diabetes and in patients with type 1 diabetes mellitus, C-peptide replacement improves renal function, skin and skeletal muscle blood flow, nerve conduction, glucose utilization, and other diabetes-related complications...
April 3, 2017: Endocrine
https://www.readbyqxmd.com/read/28361221/eighth-edition-of-ajcc-staging-for-differentiated-thyroid-cancer-is-stage-i-appropriate-for-t4-n1b-patients-aged-45-55%C3%A2-years
#19
LETTER
Pedro Weslley Rosario
No abstract text is available yet for this article.
March 30, 2017: Endocrine
https://www.readbyqxmd.com/read/28349362/androgenetic-alopecia-a-review
#20
REVIEW
Francesca Lolli, Francesco Pallotti, Alfredo Rossi, Maria C Fortuna, Gemma Caro, Andrea Lenzi, Andrea Sansone, Francesco Lombardo
PURPOSE: Androgenetic alopecia, commonly known as male pattern baldness, is the most common type of progressive hair loss disorder in men. The aim of this paper is to review recent advances in understanding the pathophysiology and molecular mechanism of androgenetic alopecia. METHODS: Using the PubMed database, we conducted a systematic review of the literature, selecting studies published from 1916 to 2016. RESULTS: The occurrence and development of androgenetic alopecia depends on the interaction of endocrine factors and genetic predisposition...
March 28, 2017: Endocrine
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