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Endocrine

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https://www.readbyqxmd.com/read/28097622/selenium-rescues-orbital-fibroblasts-from-cell-death-induced-by-hydrogen-peroxide-another-molecular-basis-for-the-effects-of-selenium-in-graves-orbitopathy
#1
LETTER
Giovanna Rotondo Dottore, Riccardo Chiarini, Maria De Gregorio, Marenza Leo, Giamberto Casini, Luca Cestari, Stefano Sellari-Franceschini, Marco Nardi, Paolo Vitti, Claudio Marcocci, Michele Marinò
No abstract text is available yet for this article.
January 17, 2017: Endocrine
https://www.readbyqxmd.com/read/28092068/differential-diagnosis-of-pituitary-masses-at-magnetic-resonance-imaging
#2
EDITORIAL
Salvatore Maria Corsello, Rosa Maria Paragliola
No abstract text is available yet for this article.
January 16, 2017: Endocrine
https://www.readbyqxmd.com/read/28092067/interrelations-among-the-adipocytokines-leptin-and-adiponectin-oxidative-stress-and-aseptic-inflammation-markers-in-pre-and-early-pubertal-normal-weight-and-obese-boys
#3
George Paltoglou, Maria Schoina, George Valsamakis, Nicolaos Salakos, Alexandra Avloniti, Athanasios Chatzinikolaou, Alexandra Margeli, Chrysanthi Skevaki, Maria Papagianni, Christina Kanaka-Gantenbein, Ioannis Papassotiriou, George P Chrousos, Ioannis G Fatouros, George Mastorakos
PURPOSE: Presumed interrelationships among deleterious aspects of adipose tissue metabolism, inflammation, and cellular oxidative stress could be influenced by pubertal hormonal changes. They were investigated in pre- and early pubertal normal-weight and obese boys before and after an exercise bout employed as an energy demanding stimulator. METHODS: Cross-sectional study. Seventy-six healthy pre- (mean ± SD, 10.6 ± 0.2 years old, 28 normal-weight, and 11 obese) and early-(11...
January 16, 2017: Endocrine
https://www.readbyqxmd.com/read/28070709/influence-of-resveratrol-on-endoplasmic-reticulum-stress-and-expression-of-adipokines-in-adipose-tissues-adipocytes-induced-by-high-calorie-diet-or-palmitic-acid
#4
Li Chen, Ting Wang, Guanjun Chen, Nuojin Wang, Li Gui, Fang Dai, Zhaohui Fang, Qiu Zhang, Yunxia Lu
PURPOSE: This study aimed to determine whether resveratrol treatment alleviates endoplasmic reticulum stress and changes the expression of adipokines in adipose tissues and cells. METHODS: 8-week-old male C57BL/6 mice were fed a high-calorie diet (HCD group) or high-calorie diet supplemented with resveratrol (high-calorie diet  + resveratrol group) for 3 months. Insulin resistance, serum lipids and proinflammatory indices, the size and inflammatory cell infiltration in subcutaneous and visceral adipose tissues were analyzed...
January 9, 2017: Endocrine
https://www.readbyqxmd.com/read/28070708/delayed-treatment-of-undescended-testes-may-promote-hypogonadism-and-infertility
#5
Julia Rohayem, Alessandra Luberto, Eberhard Nieschlag, Michael Zitzmann, Sabine Kliesch
CONTEXT: Undescended testes at birth may be caused by testosterone deficiency during fetal development. It is unclear whether the process of failed descent contributes to permanent endocrine impairment. OBJECTIVES: To evaluate the impact of age at treatment of undescended testes on endocrine and spermatogenic testicular function in middle-aged men. PATIENTS AND METHODS: Reproductive hormone and semen data of 357 men with previously undescended testes were evaluated with respect to age at correction of testicular position and compared to those of 709 controls with eutopic testes at birth and normozoospermia...
January 9, 2017: Endocrine
https://www.readbyqxmd.com/read/28063130/glucocorticoids-curtail-stimuli-induced-creb-phosphorylation-in-trh-neurons-through-interaction-of-the-glucocorticoid-receptor-with-the-catalytic-subunit-of-protein-kinase-a
#6
Israim Sotelo-Rivera, Antonieta Cote-Vélez, Rosa-María Uribe, Jean-Louis Charli, Patricia Joseph-Bravo
PURPOSE: Corticosterone prevents cold-induced stimulation of thyrotropin-releasing hormone (Trh) expression in rats, and the stimulatory effect of dibutyryl cyclic-adenosine monophosphate (dB-cAMP) on Trh transcription in hypothalamic cultures. We searched for the mechanism of this interference. METHODS: Immunohistochemical analyses of phosphorylated cAMP-response element binding protein (pCREB) were performed in the paraventricular nucleus (PVN) of Wistar rats, and in cell cultures of 17-day old rat hypothalami, or neuroblastoma SH-SY5Y cells...
January 6, 2017: Endocrine
https://www.readbyqxmd.com/read/28058528/prevalence-predictors-and-outcomes-of-steroid-induced-hyperglycemia-in-hospitalized-patients-with-hematologic-malignancies
#7
Sara J Healy, Haikady N Nagaraja, Dhuha Alwan, Kathleen M Dungan
To determine prevalence, predictors, and outcomes of steroid-induced hyperglycemia in hospitalized patients with hematologic malignancies METHODS: We performed retrospective analysis of patients who were hospitalized on any of the four hematology services or bone marrow transplant service and who received systemic steroids during a 2-month period. Mean glucoses for days 1-4 and maximum glucose were calculated and the total daily steroid dose was converted to equivalent dose of dexamethasone. Hyperglycemia was defined as any glucose >9...
January 6, 2017: Endocrine
https://www.readbyqxmd.com/read/28050685/giant-prolactinomas-multi-modal-approach-to-achieve-tumor-control
#8
EDITORIAL
Ilan Shimon
No abstract text is available yet for this article.
January 4, 2017: Endocrine
https://www.readbyqxmd.com/read/28042646/does-parathyroid-hormone-control-bone-quality
#9
EDITORIAL
Dolores Shoback
No abstract text is available yet for this article.
January 2, 2017: Endocrine
https://www.readbyqxmd.com/read/28042645/tsh-increment-and-the-risk-of-incident-type-2-diabetes-mellitus-in-euthyroid-subjects
#10
Ji Eun Jun, Sang-Man Jin, Jae Hwan Jee, Ji Cheol Bae, Kyu Yeon Hur, Moon-Kyu Lee, Sun Wook Kim, Jae Hyeon Kim
PURPOSE: Thyroid function is known to influence glucose metabolism, and thyroid-stimulating hormone is the most useful parameter in screening for thyroid dysfunction. Therefore, the aim of this study was to investigate the incidence of type 2 diabetes according to baseline thyroid-stimulating hormone level and thyroid-stimulating hormone change in euthyroid subjects. METHODS: We identified and enrolled 17,061 euthyroid subjects without diabetes among participants who had undergone consecutive thyroid function tests between 2006 and 2012 as a part of yearly health check-up program...
January 2, 2017: Endocrine
https://www.readbyqxmd.com/read/28042644/cardiovascular-comorbidities-in-acromegaly-an-update-on-their-diagnosis-and-management
#11
REVIEW
Ana M Ramos-Leví, Mónica Marazuela
Comorbidities related to the cardiovascular system are one of the most prevalent in patients with acromegaly, and contribute to an increased risk of morbidity and all-cause mortality. Specifically, hypertension, cardiomyopathy, heart valve disease, arrhythmias, atherosclerosis, coronary artery disease, and cardiac dysfunction may be frequent findings. Although the underlying physiopathology for each comorbidity may not be fully elucidated, uncontrolled growth hormone/insulin-like growth factor 1 excess, age, prolonged disease duration, and coexistence of other cardio-vascular risk factors are significant influencing variables...
January 2, 2017: Endocrine
https://www.readbyqxmd.com/read/28040834/aldehyde-dehydrogenase-activity-plays-no-functional-role-in-stem-cell-like-properties-in-anaplastic-thyroid-cancer-cell-lines
#12
Mika Shimamura, Tomomi Kurashige, Norisato Mitsutake, Yuji Nagayama
Recent studies have revealed that aldehyde dehydrogenase (ALDH) is a candidate marker for thyroid cancer stem cells, although its activity is flexible. The goal of this study is to clarify the functional significance of ALDH enzymatic activity on thyroid cancer stem cells properties in anaplastic thyroid cancer cell lines. In vitro sphere formation assay was used to judge the stemness of 4 anaplastic thyroid cancer cell lines (FRO, ACT1, 8505C, and KTC3). Two well-known ALDH inhibitors, N,N-diethylaminobenzaldehyde (DEAB) and disulfiram (DS), were first used...
December 31, 2016: Endocrine
https://www.readbyqxmd.com/read/28040833/insights-into-the-relationships-between-diabetes-prediabetes-and-cancer
#13
REVIEW
Lorenzo Scappaticcio, Maria Ida Maiorino, Giuseppe Bellastella, Dario Giugliano, Katherine Esposito
Diabetes mellitus and cancer are two growing health problems. They have in common many modifiable risk factors including sex, age, obesity, physical activity, diet, alcohol, and smoking, and have a long latency before overtly manifesting. Patients with diabetes experience a roughly 20-25% higher cancer incidence compared to individuals without diabetes, and it depends on cancer site. Moreover, patients with diabetes who further develop cancer have increased early and late mortality in comparison with cancer patients without diabetes...
December 31, 2016: Endocrine
https://www.readbyqxmd.com/read/28039560/continuous-subcutaneous-insulin-infusion-an-opportunity-for-better-care-but-not-a-magic-pill
#14
EDITORIAL
Avivit Cahn, Eytan Roitman, Genya Aharon-Hananel, Itamar Raz
No abstract text is available yet for this article.
December 30, 2016: Endocrine
https://www.readbyqxmd.com/read/28032209/periodontitis-is-associated-with-diabetic-retinopathy-in-non-obese-adults
#15
Su Jeong Song, Seong-Su Lee, Kyungdo Han, Jun-Beom Park
PURPOSE: Patients with diabetes retinopathy appear to show increased susceptibility to periodontal disease. This study was performed to assess the relationship between periodontitis and the prevalence of diabetic retinopathy in a large probability sample of the Korean population. A subgroup analysis was performed using body mass index <25 kg/m(2) as the criterion to evaluate the effect of obesity on this relationship. METHODS: This study is based on data from the Korean National Health and Nutrition Examination Survey of the Korean population, conducted between 2008 and 2010...
December 28, 2016: Endocrine
https://www.readbyqxmd.com/read/28032208/hormone-replacement-therapy-in-turner-syndrome-is-important-a-new-meta-analysis-points-at-many-shortcomings-in-the-available-literature
#16
EDITORIAL
Claus H Gravholt
No abstract text is available yet for this article.
December 28, 2016: Endocrine
https://www.readbyqxmd.com/read/28012150/at1-receptor-antagonist-induces-thermogenic-beige-adipocytes-in-the-inguinal-white-adipose-tissue-of-obese-mice
#17
Francielle Graus-Nunes, Tamiris Lima Rachid, Felipe de Oliveira Santos, Sandra Barbosa-da-Silva, Vanessa Souza-Mello
PURPOSE: To evaluate whether losartan is able to induce beige adipocytes formation, focusing on the thermogenic gene expression and adipocyte remodeling in the subcutaneous white adipose tissue of diet-induced obese mice. METHODS: Male C57BL/6 mice received a control diet (10% energy as lipids) or a high-fat diet (50% energy as lipids) for 10 weeks, followed by a 5-week treatment with losartan: control group, control-losartan group (10 mg/Kg/day), high-fat group and high-fat-losartan group (10 mg/Kg/day)...
December 23, 2016: Endocrine
https://www.readbyqxmd.com/read/28005257/safety-of-transsphenoidal-microsurgical-approach-in-patients-with-an-acth-secreting-pituitary-adenoma
#18
Carmine Antonio Donofrio, Marco Losa, Marco Gemma, Lodoviga Giudice, Lina Raffaella Barzaghi, Pietro Mortini
PURPOSE: Patients affected by Cushing's disease often have important comorbidities directly linked to hypercortisolism that might enhance the operative risk. We report the safety of transsphenoidal surgery in patients affected by Cushing's disease as compared with patients with nonfunctioning pituitary adenoma. METHODS: We have retrospectively analyzed 142 patients with Cushing's disease and 299 patients with nonfunctioning pituitary adenoma who underwent transsphenoidal surgery performed by a single experienced neurosurgeon between September 2007 and December 2014...
December 22, 2016: Endocrine
https://www.readbyqxmd.com/read/28005256/risk-factors-for-osteoporosis-2000-2012
#19
EDITORIAL
Robert A Adler
No abstract text is available yet for this article.
December 22, 2016: Endocrine
https://www.readbyqxmd.com/read/28004237/sanggenol-f-exerts-anti-diabetic-effects-via-promoting-adipocyte-differentiation-and-modifying-adipokines-expression
#20
Jing-Jie Zhu, Jun-Shang Huang, Ting Wang, Jun Ji, Ai-Jun Hou, He-Yao Wang
Adipose tissue is not only a lipid storage site, but also a well-known endocrine organ. Dysfunction of adipose tissue is associated with irregular lipid metabolism, ectopic lipid accumulation and insulin resistance. It is proposed that modulating on adipose tissue is a reasonable way to ameliorate glucose and lipid metabolism. (±)-sanggenol F (SGF, purity >98.5%) was synthesized as a racemic mixture of natural (+)-sanggenol F. In this study, SGF was found to promote adipocyte differentiation, enhance insulin sensitivity, and upregulate beneficial adipokines expression in 3T3-L1 cells...
December 21, 2016: Endocrine
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