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Endocrine

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https://www.readbyqxmd.com/read/29779168/thyroid-cancer-related-bone-metastases-increasingly-good-prospects-for-treatment
#1
EDITORIAL
Leonidas H Duntas
No abstract text is available yet for this article.
May 19, 2018: Endocrine
https://www.readbyqxmd.com/read/29774503/multiple-benefits-from-dual-release-hydrocortisone-a-hard-view-from-bones
#2
EDITORIAL
D A Vassiliadi, S Tsagarakis
No abstract text is available yet for this article.
May 17, 2018: Endocrine
https://www.readbyqxmd.com/read/29770933/risk-factors-for-central-neck-lymph-node-metastases-in-follicular-variant-vs-classic-papillary-thyroid-carcinoma
#3
Marco Raffaelli, Carmela De Crea, Luca Sessa, Guido Fadda, Celestino Pio Lombardi, Rocco Bellantone
PURPOSE: Histological variants of papillary thyroid carcinoma (PTC) have been advocated as possible risk factors for central neck nodal metastases (CNM). A lower incidence of CNM in follicular variant of papillary thyroid carcinoma (fvPTC) when compared with classic PTC (cPTC) has been observed. We aimed to compare risk factors for CNM in patients with fvPTC and cPTC. METHODS: The medical records of 1737 patients with a diagnosis of cPTC or fvPTC were reviewed. Demographic, clinical and pathological findings were prospectively registered...
May 16, 2018: Endocrine
https://www.readbyqxmd.com/read/29767287/screening-for-comorbid-conditions-in-patients-enrolled-in-the-soda-registry-a-2-year-observational-analysis
#4
Whitney W Woodmansee, Murray B Gordon, Mark E Molitch, Adriana G Ioachimescu, Don W Carver, Beloo Mirakhur, David Cox, Roberto Salvatori
PURPOSE: This 2-year analysis assessed frequency of comorbidities and comorbidity screening in the Somatuline® (lanreotide, LAN) Depot for Acromegaly (SODA) registry. METHODS: Patient data collected included pituitary hormone deficiencies, sleep studies, echocardiograms, gallbladder sonographies, colonoscopies, and glycated hemoglobin (HbA1c) levels. Insulin-like growth factor-1 (IGF-1) and growth hormone levels in patients with (DM) and without (non-DM) diabetes mellitus were analyzed...
May 16, 2018: Endocrine
https://www.readbyqxmd.com/read/29767286/pituitary-surgery-is-becoming-more-common-does-this-reflect-a-change-in-tumor-incidence-detection-or-treatment-pattern
#5
EDITORIAL
Eliza B Geer
No abstract text is available yet for this article.
May 16, 2018: Endocrine
https://www.readbyqxmd.com/read/29766454/successful-surgery-of-the-hypothalamic-region-yes-we-can
#6
EDITORIAL
Michael Buchfelder
No abstract text is available yet for this article.
May 15, 2018: Endocrine
https://www.readbyqxmd.com/read/29766453/comment-on-microsurgical-therapy-of-pituitary-adenomas
#7
Michael Buchfelder
No abstract text is available yet for this article.
May 15, 2018: Endocrine
https://www.readbyqxmd.com/read/29749566/great-veins-invasion-in-follicular-thyroid-cancer-single-centre-study-assessing-prevalence-and-clinical-outcome
#8
Maria Grazia Chiofalo, Raffaella D'Anna, Francesca Di Gennaro, Sergio Venanzio Setola, Vincenzo Marotta
PURPOSE: Great veins invasion is considered as a rare and prognostically unfavourable event in thyroid cancer. However, current knowledge about this issue is mainly based on single case reports. Follicular thyroid cancer (FTC) represents the histotype with the most pronounced angioinvasive feature. This study is aimed at assessing the actual prevalence of great veins invasion in FTC and providing information about prognosis and the proper clinical management of these patients. METHODS: Clinico-pathological and radiological data of patients with thyroid cancer undergoing thyroidectomy in our institution were retrospectively retrieved...
May 10, 2018: Endocrine
https://www.readbyqxmd.com/read/29744655/does-the-acr-ti-rads-scoring-allow-us-to-safely-avoid-unnecessary-thyroid-biopsy-single-center-analysis-in-a-large-cohort
#9
Fatos Dilan Koseoglu Atilla, Basak Ozgen Saydam, Nihat Ali Erarslan, Ayse Gulden Diniz Unlu, Hamiyet Yilmaz Yasar, Muhammet Ozer, Baris Akinci
INTRODUCTION: The American College of Radiology (ACR) has recently proposed a guideline that recommends clinicians to perform thyroid fine-needle aspiration biopsy (FNAB) on the basis of ultrasound features. In this study, we focused on nodules for which no biopsy is recommended by the ACR Thyroid Imaging, Reporting and Data System (TI-RADS) guideline. SUBJECTS AND METHODS: Two-thousand eight-hundred and forty-seven consecutive patients with thyroid nodules who underwent FNAB according to the 2009 American Thyroid Association (ATA) guideline were included...
May 9, 2018: Endocrine
https://www.readbyqxmd.com/read/29737494/the-effect-of-moderate-weight-loss-with-or-without-1-3-1-6-%C3%AE-glucan-addition-on-subcutaneous-adipose-tissue-inflammatory-gene-expression-in-young-subjects-with-uncomplicated-obesity
#10
Marek Strączkowski, Agnieszka Nikołajuk, Radosław Majewski, Remigiusz Filarski, Magdalena Stefanowicz, Natalia Matulewicz, Monika Karczewska-Kupczewska
PURPOSE: Obesity is characterized by insulin resistance and low-grade systemic and adipose tissue (AT) inflammation. It remains unclear whether beneficial effects of weight loss are related to AT inflammation. We aimed to assess the effect of weight loss during low-calorie diet on insulin sensitivity, AT expression of genes associated with inflammation in young subjects with obesity. Furthermore, we estimated the effects of immunomodulatory (1, 3)(1, 6)-β-glucan (BG) on the above parameters...
May 8, 2018: Endocrine
https://www.readbyqxmd.com/read/29736880/comparison-of-peripheral-nerve-protection-between-insulin-based-glucose-control-and-alpha-lipoic-acid-ala-in-the-streptozotocin-stz-induced-diabetic-rat
#11
Kyung Ae Lee, Na Young Lee, Tae Sun Park, Heung Yong Jin
Strict glucose control is a well-proven therapeutic approach for peripheral neuropathies in patients with diabetes. Alpha lipoic acid (ALA) has also been accepted as a therapeutic agent for diabetic peripheral neuropathy (DPN) in the respect of pathogenesis. However, the potential of ALA as a treatment for DPN in comparison to that of glucose control is unclear. In this study, we compared the neuroprotective potential of glucose control and ALA. Animals were divided into 6 groups based on the intervention used, as follows: normal, diabetes (DM), DM+racemic form of ALA, DM+R form of ALA, DM+once daily insulin glargine, and DM+once daily insulin glargine with twice daily insulin glulisine...
May 7, 2018: Endocrine
https://www.readbyqxmd.com/read/29730785/may-the-force-be-with-you-why-resistance-training-is-essential-for-subjects-with-type-2-diabetes-mellitus-without-complications
#12
REVIEW
Roberto Codella, Marta Ialacqua, Ileana Terruzzi, Livio Luzi
Physical activity, together with diet and pharmacological therapy, represents one of the three cornerstones in type 2 diabetes mellitus treatment and care. The therapeutic appeal of regular physical activity stems from: (i) its non-pharmacological nature; (ii) its beneficial effects on the metabolic risk factors associated with diabetes complications; (iii) its low costs. Evidence accumulated in the last years suggests that aerobic training-endurance training-constitutes a safe modality of intervention, achievable, and effective in diabetes treatment, whenever it is not limited by comorbidities...
May 5, 2018: Endocrine
https://www.readbyqxmd.com/read/29730784/voice-quality-preservation-in-thyroid-surgery-with-neuromonitoring
#13
Beata Wojtczak, Krzysztof Sutkowski, Krzysztof Kaliszewski, Zdzisław Forkasiewicz, Bartłomiej Knychalski, Michał Aporowicz, Marek Bolanowski, Marcin Barczyński
PURPOSE: Voice problems are common after thyroidectomy. The aim of this study was to assess the voice related quality of life after thyroidectomy with neuromonitoring. The sociodemographic and treatment factors influencing the quality of voice after the operation were investigated. METHODS: A total of 40 patients after thyroidectomy with neuromonitoring were enrolled into the study. The voice outcome was analyzed pre and postoperatively by two validated self-assessment questionnaires: Voice Handicap Index and Voice-Related Quality of Life survey...
May 5, 2018: Endocrine
https://www.readbyqxmd.com/read/29728876/kisspeptin-and-lh-pulsatile-temporal-coupling-in-pcos-patients
#14
Krzysztof Katulski, Agnieszka Podfigurna, Adam Czyzyk, Blazej Meczekalski, Alessandro D Genazzani
PURPOSE: To evaluate the temporal coupling between spontaneous kisspeptin and luteinizing hormone (LH) pulsatile releases in polycystic ovary syndrome (PCOS) patients. METHODS: We examined 71 patients diagnosed with PCOS. A 2 h pulsatility study was performed to evaluate serum kisspeptin and LH pulse frequency and concentration, sampled every 10 min; baseline follicle-stimulating hormone (FSH), estradiol (E2), prolactin (PRL), cortisol, 17-hydroksy-progesterone (17OHP), testosterone (T), free testosterone index (FTI, and insulin levels were also measured...
May 4, 2018: Endocrine
https://www.readbyqxmd.com/read/29728875/natural-history-and-clinical-characteristics-of-50-patients-with-wolfram-syndrome
#15
Gema Esteban Bueno, Dyanne Ruiz-Castañeda, Javier Ruiz Martínez, Manuel Romero Muñoz, Pedro Carrillo Alascio
PURPOSE: To describe clinical characteristics of diabetes mellitus (DM) in a group of patients with Wolfram Syndrome (WS). METHODS: Descriptive, cross-sectional observational design. The sample consisted of 50 patients diagnosed with WS. Clinical criteria contributing to WS diagnosis were analyzed: diabetes mellitus (DM), optic nerve atrophy (OA), sensorineural deafness, urological and neurological dysfunction, among others. These parameters were assessed according to their presence/absence, age of onset, and various clinical-analytical parameters...
May 4, 2018: Endocrine
https://www.readbyqxmd.com/read/29721802/microbiota-and-metabolic-diseases
#16
REVIEW
Alessia Pascale, Nicoletta Marchesi, Cristina Marelli, Adriana Coppola, Livio Luzi, Stefano Govoni, Andrea Giustina, Carmine Gazzaruso
The microbiota is a complex ecosystem of microorganisms consisting of bacteria, viruses, protozoa, and fungi, living in different districts of the human body, such as the gastro-enteric tube, skin, mouth, respiratory system, and the vagina. Over 70% of the microbiota lives in the gastrointestinal tract in a mutually beneficial relationship with its host. The microbiota plays a major role in many metabolic functions, including modulation of glucose and lipid homeostasis, regulation of satiety, production of energy and vitamins...
May 2, 2018: Endocrine
https://www.readbyqxmd.com/read/29721801/the-emerging-role-of-aldosterone-mineralocorticoid-receptors-in-the-pathogenesis-of-erectile-dysfunction
#17
REVIEW
Fei Wu, Yun Lin, Qingyong Liu
PURPOSE: Aldosterone is an old hormone that has been discovered for more than fifty years. The clinical application of its receptors' inhibitors, especially spirolactone, has benifited patients for decades worldwide. In this review, we briefly summarized the molecular mechanism of aldosterone/mineralocorticoid receptors (Ald-MRs) signaling in cardiovascular diseases and its emerging role in erectile dysfunction. METHODS: We searched PubMed, Web of Science, and Scopus for manuscripts published prior to December 2017 using key words " aldosterone " AND " erectile dysfunction " OR " cardiovascular disease " OR " mineralocorticoid receptors "...
May 2, 2018: Endocrine
https://www.readbyqxmd.com/read/29721800/the-timing-of-parathyroid-hormone-measurement-defines-the-cut-off-values-to-accurately-predict-postoperative-hypocalcemia-a-prospective-study
#18
Eduardo Bardou Yunes Filho, Rafael Vaz Machry, Rodrigo Mesquita, Rafael Selbach Scheffel, Ana Luiza Maia
PURPOSE: Serum intact parathyroid hormone (iPTH) level is an early marker of post-thyroidectomy hypocalcemia. However, lack of methodological standardization to define timing and cut-off points of iPTH measurement limit its clinical applicability. Here, we evaluated the relationship between two distinct postoperative time sampling and iPTH accuracy on predicting hypocalcemia. METHODS: iPTH was measured within 4 h after surgery (iPTH 4 h) and on the morning of the first postoperative day (iPTH 1st PO)...
May 2, 2018: Endocrine
https://www.readbyqxmd.com/read/29717464/alteration-in-skeletal-muscle-mass-in-women-with-subclinical-hypercortisolism
#19
Jae Hyeon Kim, Mi Kyung Kwak, Seong Hee Ahn, Hyeonmok Kim, Yoon Young Cho, Sunghwan Suh, Beom-Jun Kim, Kee-Ho Song, Seung Hun Lee, Jung-Min Koh
PURPOSE: Despite the well-known deleterious effects of cortisol on skeletal muscle, whether subtle cortisol excess in subclinical hypercortisolism (SH) affects skeletal muscle mass is unknown. Our objective was to understand the effects of the cortisol level on skeletal muscle mass in patients with SH. METHODS: We compared skeletal muscle mass and fat mass (FM) between 21 patients with SH (12 women and 9 men) and 224 controls (67 women and 157 men) with nonfunctioning adrenal incidentaloma (NFAI)...
May 1, 2018: Endocrine
https://www.readbyqxmd.com/read/29704156/lactate-induces-expression-and-secretion-of-fibroblast-growth-factor-21-by-muscle-cells
#20
LETTER
Joan Villarroya, Laura Campderros, Francesc Ribas-Aulinas, Audrey Carrière, Louis Casteilla, Marta Giralt, Francesc Villarroya
No abstract text is available yet for this article.
April 27, 2018: Endocrine
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