Zheng Xian Thng, Jonathan Regenold, Albert John Bromeo, Amir Akhavanrezayat, Ngoc T T Than, Anadi Khatri, S Saeed Mohammadi, Anh N T Tran, Yong Un Shin, Irmak Karaca, Hashem H Ghoraba, Christopher Chi Mong Or, Quan Dong Nguyen
INTRODUCTION: Uveitis is a heterogeneous group of ocular conditions characterized by inflammation of the uveal tract and is one of the leading causes of vision impairment. In developed countries, noninfectious uveitis (NIU) represents most cases and is challenging to treat due to its severity, chronicity, and high recurrence rates. The advent of anti-tumor necrosis factor-α (anti-TNF-α) agents have dramatically improved outcomes and changed treatment paradigms in NIU. AREAS COVERED: The index article summarizes the present experience of anti-TNF-α agents in NIU pharmacotherapy and highlights the barriers to further research and development of anti-TNF-α agents for uveitis...
February 1, 2024: Expert Opinion on Investigational Drugs