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Menopause: the Journal of the North American Menopause Society

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https://www.readbyqxmd.com/read/28419070/another-link-between-exercise-and-relief-from-postmenopausal-decline
#1
James K Pru
No abstract text is available yet for this article.
April 17, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28419069/postmenopausal-sleep-disturbance-and-sexual-dysfunction
#2
Stephanie S Faubion
No abstract text is available yet for this article.
April 17, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28419068/visual-improvements-in-vaginal-mucosa-correlate-with-symptoms-of-vva-data-from-a-double-blind-placebo-controlled-trial
#3
James A Simon, David F Archer, Risa Kagan, Brian Bernick, Shelli Graham, Ginger D Constantine, Sebastian Mirkin
OBJECTIVE: To evaluate the response of the vaginal mucosa with TX-004HR and its correlation with vulvar and vaginal atrophy (VVA) symptoms, and whether visual examination is a useful measure for assessing VVA. METHODS: REJOICE was a 12-week, phase 3, multicenter, randomized, double-blind, placebo-controlled study of a vaginal, muco-adhesive, 17β-estradiol softgel capsule (TX-004HR 4, 10, and 25 μg) in postmenopausal women with VVA and moderate-to-severe dyspareunia...
April 17, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28419067/clinical-use-of-ring-with-support-pessary-for-advanced-pelvic-organ-prolapse-and-predictors-of-its-short-term-successful-use
#4
Mou Deng, Jing Ding, Fangfang Ai, Lan Zhu
OBJECTIVE: This study aimed to evaluate the success rate, patient satisfaction and adverse events with the use of the ring with support pessary in patients with advanced pelvic organ prolapse (POP), and to identify the factors associated with successful pessary use. METHODS: In this prospective study, 151 patients with symptomatic advanced POP (POP quantification stage III/IV) came to the Centre of Obstetrics and Gynaecology, Peking Union Medical College Hospital, for POP treatment between May 2015 and December 2015...
April 17, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28399007/physiologically-assessed-hot-flashes-and-endothelial-function-among-midlife-women
#5
Rebecca C Thurston, Yuefang Chang, Emma Barinas-Mitchell, J Richard Jennings, Roland von Känel, Doug P Landsittel, Karen A Matthews
OBJECTIVE: Hot flashes are experienced by most midlife women. Emerging data indicate that they may be associated with endothelial dysfunction. No studies have tested whether hot flashes are associated with endothelial function using physiologic measures of hot flashes. We tested whether physiologically assessed hot flashes were associated with poorer endothelial function. We also considered whether age modified associations. METHODS: Two hundred seventy-two nonsmoking women reporting either daily hot flashes or no hot flashes, aged 40 to 60 years, and free of clinical cardiovascular disease, underwent ambulatory physiologic hot flash and diary hot flash monitoring; a blood draw; and ultrasound measurement of brachial artery flow-mediated dilation to assess endothelial function...
April 10, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28399006/quantitative-analysis-of-placebo-response-and-factors-associated-with-menopausal-hot-flashes
#6
Lujin Li, Ling Xu, Junyi Wu, Lidan Dong, Yinghua Lv, Qingshan Zheng
OBJECTIVE: The aim of the study was to quantitatively analyze the placebo response and the factors associated with menopausal hot flashes. METHODS: The PubMed and Cochrane Library databases were searched for placebo-controlled trials that reported the treatment of menopausal hot flashes, with a retrieval deadline of December 31, 2015. The clinical and demographic characteristics of participants and placebo responses, defined as the percentage of reduction in hot flashes at each observation time point compared with that of baseline values, were extracted from the studies...
April 10, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28399005/effects-of-a-6-month-caloric-restriction-induced-weight-loss-program-in-obese-postmenopausal-women-with-and-without-the-metabolic-syndrome-a-monet-study
#7
Ahmed Ghachem, Denis Prud'homme, Rémi Rabasa-Lhoret, Martin Brochu
OBJECTIVE: To compare the effects of a caloric restriction (CR) on body composition, lipid profile, and glucose homeostasis in obese postmenopausal women with and without metabolic syndrome (MetS). METHODS: Secondary analyses were performed on 73 inactive obese postmenopausal women (age 57.7 ± 4.8 years; body mass index 32.4 ± 4.6 kg/m) who participated in the 6-month CR arm of a study of the Montreal-Ottawa New Emerging Team. The harmonized MetS definition was used to categorize participants with MetS (n = 20, 27...
April 10, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28375937/in-reply
#8
Mirette Hanna, Caroline Diorio
No abstract text is available yet for this article.
April 3, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28375936/to-the-editor
#9
Reza Pakzad, Saeid Safiri
No abstract text is available yet for this article.
April 3, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28375935/estriol-emerging-clinical-benefits
#10
Emad S Ali, Cheyenne Mangold, Alan N Peiris
OBJECTIVE: Estriol is the main estrogen in pregnancy, but has received less attention outside gestation. It is well known that pregnancy has an immunosuppressive effect on many autoimmune diseases such as multiple sclerosis, psoriasis, thyroiditis, uveitis, and rheumatoid arthritis. Emerging evidence indicates that estriol has potential immunomodulatory benefits for many disease states including autoimmune, inflammatory, and neurodegenerative conditions. In this review, we discuss emerging roles for estriol in the treatment of menopausal symptoms, osteoporosis, cancer, hyperlipidemia, vascular disease, and multiple sclerosis...
April 3, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28350761/polycystic-ovarian-syndrome-and-the-risk-of-subsequent-primary-ovarian-insufficiency-a-nationwide-population-based-study
#11
Mei-Lien Pan, Li-Ru Chen, Hsiao-Mei Tsao, Kuo-Hu Chen
OBJECTIVE: To evaluate the risk of subsequent primary ovarian insufficiency (POI) amongst patients with a history of polycystic ovarian syndrome (PCOS). METHODS: This nationwide, population-based study is an inspection and review of data from the 1998 to 2012 Taiwan National Health Insurance Research Database. In a sample of 1,000,000 randomly sampled individuals, women with PCOS (exposure group; n = 7,049) and women without PCOS (contrast group; n = 70,490) were compared...
March 27, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28350760/involvement-of-hsp70-and-ho-1-in-the-protective-effects-of-raloxifene-on-multiple-organ-dysfunction-syndrome-by-endotoxemia-in-ovariectomized-rats
#12
Hsin-Hsueh Shen, Shieh-Yang Huang, Pao-Yun Cheng, Yen-Ju Chu, Shu-Ying Chen, Kwok-Keung Lam, Yen-Mei Lee
OBJECTIVE: Accumulating evidence demonstrates that raloxifene, a selective estrogen receptor modulator, possesses anti-inflammatory action. This study evaluates the preventive effects of long-term treatment of raloxifene on acute inflammation and multiple organ dysfunction syndrome (MODS) in ovariectomized (OVX) rats with endotoxemia and its underlying mechanism of action. METHODS: Adult female rats were OVX bilaterally to induce estrogen insufficiency. OVX rats were administered with raloxifene (1 mg/kg, gavage, once daily) for 8 weeks, beginning 1 week after surgery, followed by induction of sepsis via intravenous infusion of lipopolysaccharides (LPS; 30 mg/kg) for 4 hours...
March 27, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28350759/resveratrol-supplementation-reduces-pain-experience-by-postmenopausal-women
#13
Rachel H X Wong, Hamish M Evans, Peter R C Howe
OBJECTIVE: Pain is a common complaint among postmenopausal women. It has been postulated that vascular dysfunction caused by estrogen decline at menopause plays a key role in the initiation and progression of degradative joint disease, namely age-related osteoarthritis. We evaluated whether supplementation with resveratrol, a phytoestrogen, could improve aspects of well-being such as chronic pain that is commonly experienced by postmenopausal women. METHODS: A 14-week randomized, double-blind, placebo-controlled intervention with trans-resveratrol (75 mg, twice daily) was conducted in 80 healthy postmenopausal women...
March 27, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28350758/effects-of-ultralow-topic-estriol-dose-on-vaginal-health-and-quality-of-life-in-postmenopausal-women-who-underwent-surgical-treatment-for-pelvic-organ-prolapse
#14
Salvatore Caruso, Stefano Cianci, Salvatore Giovanni Vitale, Maria Grazia Matarazzo, Francesca Flavia Amore, Antonio Cianci
OBJECTIVE: To evaluate the efficacy of low concentrations of vaginal estriol gel in postmenopausal women with pelvic static disorders before and after vaginal surgical treatment, assessing vaginal health, sexual function, and quality of life (QoL). METHODS: Women affected by genital prolapse were enrolled. Vaginal health, QoL, and sexual function were investigated at baseline (T0), before surgery (T1), and 13 weeks after surgery (T2). At baseline, participants were randomized 1:1...
March 27, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28350757/acupuncture-for-menopausal-hot-flashes-clinical-evidence-update-and-its-relevance-to-decision-making
#15
Carolyn Ee, Simon D French, Charlie C Xue, Marie Pirotta, Helena Teede
OBJECTIVE: There is conflicting evidence on the efficacy and effectiveness of acupuncture for menopausal hot flashes. This article synthesizes the best available evidence for when women are considering whether acupuncture might be useful for menopausal hot flashes. METHODS: We searched electronic databases to identify randomized controlled trials and systematic reviews of acupuncture for menopausal hot flushes. RESULTS: The overall evidence demonstrates that acupuncture is effective when compared with no treatment, but not efficacious compared with sham...
March 27, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28323770/to-the-editor
#16
Kadri Altundag
No abstract text is available yet for this article.
March 20, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28323769/in-reply
#17
Guangning Nie, Hongyan Yang, Jian Liu, Xiaoyun Wang, Zehui He
No abstract text is available yet for this article.
March 20, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28291029/in-reply
#18
Sheila N Garland, Jun Mao
No abstract text is available yet for this article.
March 13, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28291028/tailoring-strategies-for-the-management-of-depression-in-midlife-years
#19
Claudio N Soares
Depression affects one in every five adults in North America. Women are more affected than men, possibly because of genetics, coping strategies, and hormone variations. The concept of a menopause-associated depression, however, remains a complex and controversial topic. Although hormone therapy is not recommended as first-line therapy for depression in midlife women, estrogen-based hormone therapy may minimize the need for or enhance the response to antidepressant or behavior-based therapies in select perimenopausal women...
March 13, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28291027/estrogen-and-dpp-4-inhibitor-share-similar-efficacy-in-reducing-brain-pathology-caused-by-cardiac-ischemia-reperfusion-injury-in-both-lean-and-obese-estrogen-deprived-rats
#20
Wasana Pratchayasakul, Sivaporn Sivasinprasasn, Piangkwan Sa-Nguanmoo, Cicely Proctor, Sasiwan Kerdphoo, Nipon Chattipakorn, Siriporn C Chattipakorn
OBJECTIVE: Cardiac ischemia-reperfusion injury (I/R) caused an oxidative burst, increased beta-amyloid production, and decreased dendritic spine density in the brain. However, the effect of cardiac I/R in the brain of estrogen-deprived rats who were or were not obese have not been investigated. Moreover, the benefits of estrogen or dipeptidyl peptidase-4 (DDP-4) inhibitor therapies in those conditions have never been determined. We hypothesized that cardiac I/R aggravates brain pathology in estrogen-deprived obese rats, to a greater extent when compared with estrogen-deprived lean rats, and treatment with either estrogen or a DPP-4 inhibitor attenuates those adverse effects...
March 13, 2017: Menopause: the Journal of the North American Menopause Society
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