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Menopause: the Journal of the North American Menopause Society

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https://www.readbyqxmd.com/read/28350761/polycystic-ovarian-syndrome-and-the-risk-of-subsequent-primary-ovarian-insufficiency-a-nationwide-population-based-study
#1
Mei-Lien Pan, Li-Ru Chen, Hsiao-Mei Tsao, Kuo-Hu Chen
OBJECTIVE: To evaluate the risk of subsequent primary ovarian insufficiency (POI) amongst patients with a history of polycystic ovarian syndrome (PCOS). METHODS: This nationwide, population-based study is an inspection and review of data from the 1998 to 2012 Taiwan National Health Insurance Research Database. In a sample of 1,000,000 randomly sampled individuals, women with PCOS (exposure group; n = 7,049) and women without PCOS (contrast group; n = 70,490) were compared...
March 27, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28350760/involvement-of-hsp70-and-ho-1-in-the-protective-effects-of-raloxifene-on-multiple-organ-dysfunction-syndrome-by-endotoxemia-in-ovariectomized-rats
#2
Hsin-Hsueh Shen, Shieh-Yang Huang, Pao-Yun Cheng, Yen-Ju Chu, Shu-Ying Chen, Kwok-Keung Lam, Yen-Mei Lee
OBJECTIVE: Accumulating evidence demonstrates that raloxifene, a selective estrogen receptor modulator, possesses anti-inflammatory action. This study evaluates the preventive effects of long-term treatment of raloxifene on acute inflammation and multiple organ dysfunction syndrome (MODS) in ovariectomized (OVX) rats with endotoxemia and its underlying mechanism of action. METHODS: Adult female rats were OVX bilaterally to induce estrogen insufficiency. OVX rats were administered with raloxifene (1 mg/kg, gavage, once daily) for 8 weeks, beginning 1 week after surgery, followed by induction of sepsis via intravenous infusion of lipopolysaccharides (LPS; 30 mg/kg) for 4 hours...
March 27, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28350759/resveratrol-supplementation-reduces-pain-experience-by-postmenopausal-women
#3
Rachel H X Wong, Hamish M Evans, Peter R C Howe
OBJECTIVE: Pain is a common complaint among postmenopausal women. It has been postulated that vascular dysfunction caused by estrogen decline at menopause plays a key role in the initiation and progression of degradative joint disease, namely age-related osteoarthritis. We evaluated whether supplementation with resveratrol, a phytoestrogen, could improve aspects of well-being such as chronic pain that is commonly experienced by postmenopausal women. METHODS: A 14-week randomized, double-blind, placebo-controlled intervention with trans-resveratrol (75 mg, twice daily) was conducted in 80 healthy postmenopausal women...
March 27, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28350758/effects-of-ultralow-topic-estriol-dose-on-vaginal-health-and-quality-of-life-in-postmenopausal-women-who-underwent-surgical-treatment-for-pelvic-organ-prolapse
#4
Salvatore Caruso, Stefano Cianci, Salvatore Giovanni Vitale, Maria Grazia Matarazzo, Francesca Flavia Amore, Antonio Cianci
OBJECTIVE: To evaluate the efficacy of low concentrations of vaginal estriol gel in postmenopausal women with pelvic static disorders before and after vaginal surgical treatment, assessing vaginal health, sexual function, and quality of life (QoL). METHODS: Women affected by genital prolapse were enrolled. Vaginal health, QoL, and sexual function were investigated at baseline (T0), before surgery (T1), and 13 weeks after surgery (T2). At baseline, participants were randomized 1:1...
March 27, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28350757/acupuncture-for-menopausal-hot-flashes-clinical-evidence-update-and-its-relevance-to-decision-making
#5
Carolyn Ee, Simon D French, Charlie C Xue, Marie Pirotta, Helena Teede
OBJECTIVE: There is conflicting evidence on the efficacy and effectiveness of acupuncture for menopausal hot flashes. This article synthesizes the best available evidence for when women are considering whether acupuncture might be useful for menopausal hot flashes. METHODS: We searched electronic databases to identify randomized controlled trials and systematic reviews of acupuncture for menopausal hot flushes. RESULTS: The overall evidence demonstrates that acupuncture is effective when compared with no treatment, but not efficacious compared with sham...
March 27, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28323770/to-the-editor
#6
Kadri Altundag
No abstract text is available yet for this article.
March 20, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28323769/in-reply
#7
Guangning Nie, Hongyan Yang, Jian Liu, Xiaoyun Wang, Zehui He
No abstract text is available yet for this article.
March 20, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28323768/use-of-cardiovascular-age-for-assessing-risks-and-benefits-of-menopausal-hormone-therapy
#8
Richard J Santen
The Women's Health Initiative studies and others have suggested that menopausal hormone therapy may enhance the risk of new cardiovascular (CV) events in older women and diminish the development of coronary atherosclerosis in younger women. The underlying mechanisms to explain these findings are encapsulated in the term "Timing Hypothesis." Extensive pathophysiologic studies have provided mechanistic evidence for the dichotomous effects of estrogen on coronary artery vasculature. Early in the atherosclerotic disease process, estrogen exerts protective effects on the endothelium and retards plaque formation...
March 20, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28291031/a-sex-specific-dose-response-curve-for-testosterone-could-excessive-testosterone-limit-sexual-interaction-in-women
#9
Jill M Krapf, James A Simon
Testosterone treatment increases sexual desire and well-being in women with hypoactive sexual desire disorder; however, many studies have shown only modest benefits limited to moderate doses. Unlike men, available data indicate women show a bell-shaped dose-response curve for testosterone, wherein a threshold dosage of testosterone leads to desirable sexual function effects, but exceeding this threshold results in a lack of further positive sexual effects or may have a negative impact. Emotional and physical side-effects of excess testosterone, including aggression and virilization, may counteract the modest benefits on sexual interaction, providing a possible explanation for a threshold dose of testosterone in women...
March 13, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28291030/precision-menopausal-medicine
#10
Hugh S Taylor
No abstract text is available yet for this article.
March 13, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28291029/in-reply
#11
Sheila N Garland, Jun Mao
No abstract text is available yet for this article.
March 13, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28291028/tailoring-strategies-for-the-management-of-depression-in-midlife-years
#12
Claudio N Soares
Depression affects one in every five adults in North America. Women are more affected than men, possibly because of genetics, coping strategies, and hormone variations. The concept of a menopause-associated depression, however, remains a complex and controversial topic. Although hormone therapy is not recommended as first-line therapy for depression in midlife women, estrogen-based hormone therapy may minimize the need for or enhance the response to antidepressant or behavior-based therapies in select perimenopausal women...
March 13, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28291027/estrogen-and-dpp-4-inhibitor-share-similar-efficacy-in-reducing-brain-pathology-caused-by-cardiac-ischemia-reperfusion-injury-in-both-lean-and-obese-estrogen-deprived-rats
#13
Wasana Pratchayasakul, Sivaporn Sivasinprasasn, Piangkwan Sa-Nguanmoo, Cicely Proctor, Sasiwan Kerdphoo, Nipon Chattipakorn, Siriporn C Chattipakorn
OBJECTIVE: Cardiac ischemia-reperfusion injury (I/R) caused an oxidative burst, increased beta-amyloid production, and decreased dendritic spine density in the brain. However, the effect of cardiac I/R in the brain of estrogen-deprived rats who were or were not obese have not been investigated. Moreover, the benefits of estrogen or dipeptidyl peptidase-4 (DDP-4) inhibitor therapies in those conditions have never been determined. We hypothesized that cardiac I/R aggravates brain pathology in estrogen-deprived obese rats, to a greater extent when compared with estrogen-deprived lean rats, and treatment with either estrogen or a DPP-4 inhibitor attenuates those adverse effects...
March 13, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28291026/parity-and-increased-risk-of-insulin-resistance-in-postmenopausal-women-the-2010-korean-national-health-and-nutrition-examination-survey
#14
Jin Hwi Kim, Sung Jong Lee
OBJECTIVE: The objective of this study was to assess the association between parity and insulin resistance in nondiabetic, postmenopausal women. METHODS: This cross-sectional study was conducted using data from the 2010 Korean National Health and Nutrition Examination Survey administered by the Korean Ministry of Health and Welfare. A total of 1,243 nondiabetic postmenopausal women were included in this study and subdivided into three groups according to parity (1-2, 3-4, and ≥5 live births)...
March 13, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28266949/efficacy-of-a-biobehavioral-intervention-for-hot-flashes-a-randomized-controlled-pilot-study
#15
Debra L Barton, Kelliann C Fee Schroeder, Tanima Banerjee, Sherry Wolf, Timothy Z Keith, Gary Elkins
OBJECTIVE: The need for effective nonhormonal treatments for hot flash management without unwanted side effects continues. The primary aim of this pilot study was to evaluate the effect of combining a nonhormonal pharmacologic agent with a behavioral treatment for hot flash reduction. METHODS: Seventy-one postmenopausal women were randomized to one of four groups: venlafaxine 75 mg + hypnosis (VH) versus venlafaxine 75 mg + sham hypnosis (VSH) versus a placebo pill + hypnosis (PH) versus placebo pill + sham hypnosis (PSH)...
March 6, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28266948/to-the-editor
#16
Sheila N Garland, Jun J Mao
No abstract text is available yet for this article.
March 6, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28266947/to-the-editor
#17
Carolina Vicente Banzoli, Andréia Gomes Bezerra, Sergio Tufik, Helena Hachul
No abstract text is available yet for this article.
March 6, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28266946/self-reported-height-in-postmenopausal-women-precise-is-nice-and-sometimes-necessary
#18
Raja A Sayegh
No abstract text is available yet for this article.
March 6, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28244935/to-the-editor
#19
Jose M Moran, Ignacio Aliaga, Juan D Pedrera-Zamorano, Antonio Sánchez Fernández
No abstract text is available yet for this article.
February 27, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28225431/menopause-and-big-data-word-adjacency-graph-modeling-of-menopause-related-chacha-data
#20
Janet S Carpenter, Doyle Groves, Chen X Chen, Julie L Otte, Wendy R Miller
OBJECTIVE: To detect and visualize salient queries about menopause using Big Data from ChaCha. METHODS: We used Word Adjacency Graph (WAG) modeling to detect clusters and visualize the range of menopause-related topics and their mutual proximity. The subset of relevant queries was fully modeled. We split each query into token words (ie, meaningful words and phrases) and removed stopwords (ie, not meaningful functional words). The remaining words were considered in sequence to build summary tables of words and two and three-word phrases...
February 20, 2017: Menopause: the Journal of the North American Menopause Society
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