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Menopause: the Journal of the North American Menopause Society

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https://www.readbyqxmd.com/read/29206779/concentration-range-of-serum-sex-steroids-in-normal-postmenopausal-women-and-those-with-diagnosis-of-vulvovaginal-atrophy
#1
Yuyong Ke, Alain Bélanger, Jean-Nicolas Simard, Renaud Gonthier, Céline Martel, Mario Vaillancourt, Fernand Labrie
OBJECTIVE: The aim of the study was to determine the range of serum sex-related steroids in normal postmenopausal women and in women of the same age with a diagnosis of vulvovaginal atrophy (VVA). METHODS: Validated mass spectrometry-based assays coupled to gas or liquid chromatography were used over a 10-year period for steroid measurements. Serum samples were obtained in up to 1,512 women aged 55 to 65 years. RESULTS: Serum estrone sulfate (E1S) and androsterone glucuronide (ADT-G), the main metabolites of estrogens and androgens, respectively, were 16...
December 4, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29206778/urinary-incontinence-finding-a-voice-to-talk-about-it
#2
Emily Von Bargen
No abstract text is available yet for this article.
December 4, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29206777/to-the-editor
#3
Umberto Leone Roberti Maggiore, Simone Ferrero
No abstract text is available yet for this article.
December 4, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29206776/in-reply
#4
Marcelo Luis Steiner, Vera Lucia Cruz, Luciano de Melo Pompei
No abstract text is available yet for this article.
December 4, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29206775/menopause-improves-the-predictive-value-of-common-cardiovascular-risk-scores-in-women-with-premature-coronary-artery-disease
#5
Karolina Ewa Kryczka, Mariusz Kruk, Walerian Piotrowski, Ewa Księżycka, Radosław Pracoń, Adam Witkowski, Marcin Demkow, Barbara Lubiszewska
OBJECTIVE: Menopause, particularly its early stage (≤3 years from onset), may be an important risk factor for premature coronary artery disease. The objective of the study was to assess whether the addition of the presence of menopause in women with premature coronary artery disease could improve the predictive value of the Atherosclerotic Cardiovascular Disease risk estimator and the Systematic COronary Risk Evaluation model. METHODS: The case-control study included 307 women with coronary artery disease aged 55 or less, and 347 age-matched controls without coronary artery disease...
December 4, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29206774/associations-between-improvement-in-genitourinary-symptoms-of-menopause-and-changes-in-the-vaginal-ecosystem
#6
Caroline M Mitchell, Sujatha Srinivasan, Anna Plantinga, Michael C Wu, Susan D Reed, Katherine A Guthrie, Andrea Z LaCroix, Tina Fiedler, Matthew Munch, Congzhou Liu, Noah G Hoffman, Ian A Blair, Katherine Newton, Ellen W Freeman, Hadine Joffe, Lee Cohen, David N Fredricks
OBJECTIVE: The aim of the study was to identify associations between improvement in genitourinary symptoms of menopause (GSM) and vaginal microbiota, vaginal glycogen, and serum estrogen. METHODS: Thirty postmenopausal women enrolled in a hot flash treatment trial (oral estradiol vs venlafaxine vs placebo) who reported GSM and provided vaginal swabs at 0, 4, and 8 weeks were studied. Bacterial communities were characterized using deep sequencing targeting the 16S rRNA gene V3-V4 region...
December 4, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29206773/trauma-exposure-and-endothelial-function-among-midlife-women
#7
Rebecca C Thurston, Emma Barinas-Mitchell, Roland von Känel, Yuefang Chang, Karestan C Koenen, Karen A Matthews
OBJECTIVE: Trauma is a potent exposure that can have implications for health. However, little research has considered whether trauma exposure is related to endothelial function, a key process in the pathophysiology of cardiovascular disease (CVD). We tested whether exposure to traumatic experiences was related to poorer endothelial function among midlife women, independent of CVD risk factors, demographic factors, psychosocial factors, or a history of childhood abuse. METHODS: In all, 272 nonsmoking perimenopausal and postmenopausal women aged 40 to 60 years without clinical CVD completed the Brief Trauma Questionnaire, the Child Trauma Questionnaire, physical measures, a blood draw, and a brachial ultrasound for assessment of brachial artery flow-mediated dilation (FMD)...
December 4, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29206772/to-the-editor
#8
Andrea Stein
No abstract text is available yet for this article.
December 4, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29206771/vasomotor-symptom-characteristics-are-they-risk-factors-for-incident-diabetes
#9
Kristen E Gray, Jodie G Katon, Erin S LeBlanc, Nancy F Woods, Lori A Bastian, Gayle E Reiber, Julie C Weitlauf, Karin M Nelson, Andrea Z LaCroix
OBJECTIVE: Vasomotor symptoms (VMS), encompassing hot flashes and night sweats, may be associated with diabetes, but evidence is limited. We sought to estimate these associations. METHODS: Among 150,007 postmenopausal Women's Health Initiative participants from 1993 to 2014, we prospectively examined associations of incident diabetes with VMS characteristics at enrollment: any VMS, severity (mild/ moderate/severe), type (hot flashes/night sweats), timing (early [premenopausal or perimenopausal]/late [postmenopausal]), and duration...
December 4, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29206770/the-cross-sectional-association-between-chemerin-and-bone-health-in-peri-pre-and-postmenopausal-women-results-from-the-epic-potsdam-study
#10
Juliane Menzel, Ronald Biemann, Krasimira Aleksandrova, Matthias B Schulze, Heiner Boeing, Berend Isermann, Cornelia Weikert
OBJECTIVE: Recent in vitro data suggested that the novel adipokine chemerin may influence bone health. However, only limited evidence of the relationship between chemerin and bone health in humans is available. Therefore, this study aimed to investigate the association between chemerin and broadband ultrasound attenuation (BUA) in peri/premenopausal and postmenopausal women. METHODS: Data from the German population-based European Prospective Investigation into Cancer and Nutrition-Potsdam cohort comprising 404 peri/premenopausal and 279 postmenopausal women were analyzed...
December 4, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29206769/severe-menopausal-symptoms-associated-with-reduced-adherence-to-antiretroviral-therapy-among-perimenopausal-and-menopausal-women-living-with-hiv-in-metro-vancouver
#11
Putu K Duff, Deborah M Money, Gina S Ogilvie, Florence Ranville, Mary Kestler, Melissa C Braschel, Neora Pick, Kate Shannon
OBJECTIVES: Although more women living with HIV (WLWH) are entering midlife, the experiences of perimenopausal and menopausal WLWH, including the effects of menopausal symptoms severity, remain understudied. This study longitudinally investigated the correlates of antiretroviral therapy (ART) adherence among perimenopausal and menopausal WLWH from Metro Vancouver. METHODS: Analyses drew on longitudinal data (2014-2017) from Sexual health and HIV/AIDS: Women's Longitudinal Needs Assessment, an ongoing community-based cohort of WLWH, aged 14+, from Metro Vancouver, Canada...
December 4, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29210881/do-social-determinants-of-health-make-a-difference-in-the-age-at-natural-menopause-in-canada
#12
Marla Shapiro
No abstract text is available yet for this article.
November 27, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29210880/in-reply
#13
Eric R Sokol
No abstract text is available yet for this article.
November 27, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29189603/the-dynamics-of-stress-and-fatigue-across-menopause-attractors-coupling-and-resilience
#14
Lisa Taylor-Swanson, Alexander E Wong, David Pincus, Jonathan E Butner, Jennifer Hahn-Holbrook, Mary Koithan, Kathryn Wann, Nancy F Woods
OBJECTIVE: The objective of this study was to evaluate the regulatory dynamics between stress and fatigue experienced by women during the menopausal transition (MT) and early postmenopause (EPM). Fatigue and perceived stress are commonly experienced by women during the MT and EPM. We sought to discover relationships between these symptoms and to employ these symptoms as possible markers for resilience. METHODS: Participants were drawn from the longitudinal Seattle Midlife Women's Health Study...
November 20, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29189602/the-history-and-basic-science-development-of-soy-isoflavones
#15
Kenneth D R Setchell
This review summarizes the 2016 NAMS/Pfizer-Wulf H. Utian Endowed Lecture that focused on the history and basic science of soy isoflavones. Described is a personal perspective of the background and history that led to the current interest in soy and isoflavones with a specific focus on the role that soy isoflavones play in the health of postmenopausal women. This overview covers the metabolism and physiological behavior of isoflavones, their biological properties that are of potential relevance to aging, issues related to the safety of soy isoflavones, and the role of the important intestinally derived metabolite S-(-)equol...
November 20, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29189601/more-evidence-why-the-product-labeling-for-low-dose-vaginal-estrogen-should-be-changed
#16
Cynthia A Stuenkel
No abstract text is available yet for this article.
November 20, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29189600/pharmacoeconomic-and-associated-cost-savings-among-women-who-were-prescribed-systemic-conjugated-estrogens-therapy-compared-with-those-without-menopausal-therapy
#17
Wing Yu Tang, Dale Grothe, Allison Keshishian, Diana Morgenstern, Seema Haider
OBJECTIVE: To explore changes in healthcare costs among postmenopausal women in a commercial population who were prescribed conjugated estrogens for menopausal symptoms. METHODS: Using the MarketScan dataset from April 1, 2008 through September 30, 2012, postmenopausal women aged ≥45 years, who were prescribed conjugated estrogen tablets (Premarin), were identified. A comparative cohort of postmenopausal women with vasomotor symptoms without any menopause therapy was also identified...
November 20, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29189599/local-estrogen-benefits-of-postmenopausal-women-with-dyspareunia-data-confirming-what-clinicians-already-know
#18
Gloria Bachmann, Nancy Phillips
No abstract text is available yet for this article.
November 20, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29135897/is-bmi-a-valid-measure-of-obesity-in-postmenopausal-women
#19
Hailey R Banack, Jean Wactawski-Wende, Kathleen M Hovey, Andrew Stokes
OBJECTIVE: Body mass index (BMI) is a widely used indicator of obesity status in clinical settings and population health research. However, there are concerns about the validity of BMI as a measure of obesity in postmenopausal women. Unlike BMI, which is an indirect measure of obesity and does not distinguish lean from fat mass, dual-energy x-ray absorptiometry (DXA) provides a direct measure of body fat and is considered a gold standard of adiposity measurement. The goal of this study is to examine the validity of using BMI to identify obesity in postmenopausal women relative to total body fat percent measured by DXA scan...
November 13, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29112596/increased-cardiac-and-stroke-death-risk-in-the-first-year-after-discontinuation-of-postmenopausal-hormone-therapy
#20
Minttu Venetkoski, Hanna Savolainen-Peltonen, Päivi Rahkola-Soisalo, Fabian Hoti, Pia Vattulainen, Mika Gissler, Olavi Ylikorkala, Tomi S Mikkola
OBJECTIVE: The aim of the study was to evaluate the risk of cardiac and stroke deaths in women who discontinue postmenopausal hormone therapy (HT). METHODS: We analyzed the risk of death due to cardiac (n = 5,204) and cerebrovascular (n = 3,434) causes in Finnish women who discontinued systemic HT during 1994 to 2013 (n = 432,775). The risks were compared with those in the age-matched female background population and with those in age-matched HT users...
November 13, 2017: Menopause: the Journal of the North American Menopause Society
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