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Menopause: the Journal of the North American Menopause Society

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https://www.readbyqxmd.com/read/27922943/letters-to-the-editor
#1
Ann Steiner
No abstract text is available yet for this article.
December 5, 2016: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/27922942/letters-to-the-editor
#2
Allison J Huang, Peter Ganz, Deborah Grady, Steven R Cummings
No abstract text is available yet for this article.
December 5, 2016: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/27922941/exercise-training-ameliorates-glucosamine-induced-insulin-resistance-in-ovariectomized-rats
#3
Chung-Hwan Chen, Tsang-Hai Huang, Tsung-Lin Cheng, Chi-Fen Chang, Chau-Zen Wang, Meng-Hsing Wu, Lin Kang
OBJECTIVE: Glucosamine (GlcN), which has been reported to induce insulin resistance (IR), is a popular nutritional supplement used to treat osteoarthritis in menopausal women. We previously demonstrated that GlcN treatment caused IR in ovariectomized rats by reducing the expression of glucose transport protein subtype 4 (GLUT-4) in skeletal muscle. In the present study, we hypothesized that endurance exercise training can reverse GlcN-induced IR. METHODS: Fifty female rats were randomly divided into five groups with 10 rats in each group: (1) sham-operated group; (2) sham-operated group with GlcN treatment for 14 days; (3) ovariectomy (OVX) group; (4) OVX with GlcN treatment; and (5) OVX with GlcN treatment followed by exercise training (running program) for 8 weeks...
December 5, 2016: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/27922940/impact-of-menopausal-status-on-negative-mood-and-depressive-symptoms-in-a-longitudinal-sample-spanning-20-years
#4
Katherine E Campbell, Lorraine Dennerstein, Sue Finch, Cassandra E Szoeke
OBJECTIVE: Studies examining depressive symptoms and negative mood across the postmenopause are lacking, particularly those that examine prevalence in early and late postmenopause. This study examines negative mood and depressive occurrence in the menopausal stages to provide a better understanding of prevalence of mood disturbance during this period. METHODS: This study was a longitudinal assessment of variables drawn from an epidemiological prospective study of women's healthy aging...
December 5, 2016: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/27922939/telomere-length-is-longer-in-women-with-late-maternal-age
#5
Erin Fagan, Fangui Sun, Harold Bae, Irma Elo, Stacy L Andersen, Joseph Lee, Kaare Christensen, Bharat Thyagarajan, Paola Sebastiani, Thomas Perls, Lawrence S Honig, Nicole Schupf
OBJECTIVE: Maternal age at birth of last child has been associated with maternal longevity. The aim of this study was to determine whether older women with a history of late maternal age at last childbirth had a longer leukocyte telomere length than those with maternal age at last childbirth of 29 years or less. METHODS: A nested case control study was conducted using data from the Long Life Family Study. Three hundred eighty-seven women who gave birth to at least one child and lived to the top fifth percentile of their birth cohort, or died before the top fifth percentile of their birth cohort died, but were at least 70 years old, were studied...
December 5, 2016: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/27922938/skeletal-muscle-mass-is-associated-with-higher-dietary-protein-intake-and-lower-body-fat-in-postmenopausal-women-a-cross-sectional-study
#6
Thaís R Silva, Poli M Spritzer
OBJECTIVE: We investigated the association between skeletal muscle mass and dietary protein intake, habitual physical activity, body composition, and metabolic variables. METHODS: One hundred three healthy postmenopausal women from southern Brazil (age 55.2 ± 4.9 y, body mass index 27.2 ± 4.6 kg/m) were enrolled. Bone mineral density, %body fat, %trunk fat mass, and appendicular lean mass were assessed by dual-energy x-ray absorptiometry, resting metabolic rate by indirect calorimetry, and habitual physical activity by pedometer...
December 5, 2016: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/27922937/repurposing-ospemifene-for-potentiating-an-antigen-specific-immune-response
#7
Chiao-Jung Kao, Gregory T Wurz, Yi-Chen Lin, Daniel P Vang, Brian Phong, Michael W DeGregorio
OBJECTIVE: Ospemifene, an estrogen receptor agonist/antagonist approved for the treatment of dyspareunia and vaginal dryness in postmenopausal women, has potential new indications as an immune modulator. The overall objective of the present series of preclinical studies was to evaluate the immunomodulatory activity of ospemifene in combination with a peptide cancer vaccine. METHODS: Immune regulating effects, mechanism of action and structure activity relationships of ospemifene and related compounds were evaluated by examining expression of T-cell activating cytokines in vitro, and antigen-specific immune response and cytotoxic T-lymphocyte activity in vivo...
December 5, 2016: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/27922936/the-rejoice-trial-a-phase-3-randomized-controlled-trial-evaluating-the-safety-and-efficacy-of-a-novel-vaginal-estradiol-soft-gel-capsule-for-symptomatic-vulvar-and-vaginal-atrophy
#8
Ginger D Constantine, James A Simon, James H Pickar, David F Archer, Harvey Kushner, Brian Bernick, Gina Gasper, Shelli Graham, Sebastian Mirkin
OBJECTIVE: To evaluate the safety and efficacy of TX-004HR vaginal estradiol soft-gel capsules for moderate-to-severe dyspareunia associated with postmenopausal vulvar and vaginal atrophy. METHODS: In this randomized, double-blind, placebo-controlled, phase 3 study, postmenopausal women with a self-identified most bothersome symptom of dyspareunia received 4, 10, or 25 μg TX-004HR or placebo for 12 weeks. Four co-primary efficacy endpoints were change from baseline to week 12 in percentages of superficial and parabasal cells, vaginal pH, and severity of dyspareunia...
December 5, 2016: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/27922935/enhancing-memory-self-efficacy-during-menopause-through-a-group-memory-strategies-program
#9
Anne E Unkenstein, Bei Bei, Christina A Bryant
OBJECTIVE: Anxiety about memory during menopause can affect quality of life. We aimed to improve memory self-efficacy during menopause using a group memory strategies program. METHODS: The program was run five times for a total of 32 peri- and postmenopausal women, age between 47 and 60 years, recruited from hospital menopause and gynecology clinics. The 4-week intervention consisted of weekly 2-hour sessions, and covered how memory works, memory changes related to ageing, health and lifestyle factors, and specific memory strategies...
December 5, 2016: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/27922934/psychometric-properties-of-the-chinese-version-of-the-menopause-specific-quality-of-life-questionnaire
#10
Guangning Nie, Hongyan Yang, Jian Liu, ChunMei Zhao, Xiaoyun Wang
OBJECTIVE: The Menopause-Specific Quality-of-Life (MENQOL) questionnaire was developed as a specific tool to measure the health-related quality-of-life of postmenopausal women. Thus far, the Chinese version questionnaire has not been subjected to psychometric assessment with a large sample. This study aims to evaluate the validity and reliability of the Chinese version of the MENQOL specific to postmenopausal women in China. METHODS: A total of 1,137 menopausal symptomatic and 491 menopausal asymptomatic women from eight cities in China were recruited using a convenience sampling method...
December 5, 2016: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/27922933/the-cross-sectional-association-between-vasomotor-symptoms-and-hemostatic-parameter-levels-in-postmenopausal-women
#11
Laura B Harrington, Marc Blondon, Mary Cushman, Andrew M Kaunitz, Jacques E Rossouw, Matthew A Allison, Lisa W Martin, Karen C Johnson, Jan Rosing, Nancy F Woods, Andrea Z LaCroix, Susan R Heckbert, Barbara McKnight, Nicholas L Smith
OBJECTIVE: Vasomotor symptoms (VMS) may be a marker of cardiovascular risk. We aimed to evaluate the cross-sectional association of VMS presence and severity with hemostatic parameter levels measured at baseline among Women's Health Initiative (WHI) Hormone Therapy trial postmenopausal participants. METHODS: This cross-sectional analysis included 2,148 postmenopausal women with measures of VMS presence and severity reported in the 4 weeks before WHI baseline, who were not using warfarin or hormone therapy and for whom the following baseline hemostatic parameters were measured within the WHI Cardiovascular Disease Biomarker Case-Control Study: antithrombin, plasminogen activator inhibitor-1, protein C antigen, total and free protein S antigen, total and free tissue factor pathway inhibitor, D-dimer, normalized activated protein C sensitivity ratio, and thrombin generation...
December 5, 2016: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/27922932/letters-to-the-editor
#12
Luiz Gustavo Oliveira Brito, Cassia Raquel T Juliato
No abstract text is available yet for this article.
December 5, 2016: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/27898652/natural-mineral-rich-water-ingestion-by-ovariectomized-fructose-fed-sprague-dawley-rats-effects-on-sirtuin-1-and-glucocorticoid-signaling-pathways
#13
Jugal Kishore Das, Milton Severo, Cidália Dionísio Pereira, Emília Patrício, José Magalhães, Rosário Monteiro, Delminda Neves, Maria João Martins
OBJECTIVE: Prevention or induction of metabolic disorders and obesity depend on estrogen signaling and/or exogenous factors, such as mineral content in diet. The protective effects of a Portuguese natural mineral-rich water against the induction of metabolic syndrome in fructose-fed male Sprague-Dawley rats have been reported. The present study was designed to assess the impact of this mineral-rich water on fructose-fed estrogen-deficient female Sprague-Dawley rats. METHODS: Ovariectomized rats had access to tap (TWO) or mineral-rich (MWO) waters, with and without 10% fructose (10-wk treatment)...
November 28, 2016: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/27898651/prevalence-and-correlates-of-vaginal-estrogenization-in-postmenopausal-women-in-the-united-states
#14
Stacy Tessler Lindau, Annie Dude, Natalia Gavrilova, Joscelyn N Hoffmann, L Philip Schumm, Martha K McClintock
OBJECTIVE: This work aims to establish current population-based vaginal estrogenization norms for postmenopausal US women. METHODS: Using a US national probability sample of 868 postmenopausal women ages 57 to 85 years (mean age 67.6 ± 0.3 y, 21.6 ± 0.5 y since menopause), we calculated the epithelial maturation value (MV) generated from self-collected vaginal specimens and compared findings with historical clinical data. Linear and logistic regressions were used to describe the relationship between vaginal estrogenization and sociodemographic, physical, gynecologic, and sexual characteristics...
November 28, 2016: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/27898650/letters-to-the-editor
#15
Angelo Cagnacci, Federica Palma, Anjeza Xholli
No abstract text is available yet for this article.
November 28, 2016: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/27875390/links-between-reproductive-factors-and-general-health
#16
Sybil L Crawford
No abstract text is available yet for this article.
November 21, 2016: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/27875389/comparative-effectiveness-of-electro-acupuncture-versus-gabapentin-for-sleep-disturbances-in-breast-cancer-survivors-with-hot-flashes-a-randomized-trial
#17
Sheila N Garland, Sharon X Xie, Qing Li, Christina Seluzicki, Coby Basal, Jun J Mao
OBJECTIVE: Sleep disturbance is a major consequence of hot flashes among breast cancer survivors. This study evaluated the effects of electro-acupuncture (EA) versus gabapentin (GP) for sleep disturbances among breast cancer survivors experiencing daily hot flashes. METHODS: We analyzed data from a randomized controlled trial involving 58 breast cancer survivors experiencing bothersome hot flashes at least two times per day. Participants were randomly assigned to receive 8 weeks of EA or daily GP (total dose of 900 mg/d)...
November 21, 2016: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/27875388/is-vulvovaginal-atrophy-due-to-a-lack-of-both-estrogens-and-androgens
#18
Fernand Labrie, Céline Martel, Georges Pelletier
OBJECTIVE: The aim of this study was to review the preclinical data showing the role of both estrogens and androgens in the physiology of the vagina, and, most likely, in vulvovaginal atrophy of menopause. METHODS: Mass spectrometry-based assays (validated according to the FDA guidelines) for the measurement of sex steroids, their precursors, and metabolites were used. In addition to fixation of the vagina for morphological examination, histomorphometry, immunocytochemistry, immunofluorescence, and quantitative reverse transcription polymerase chain reaction were performed...
November 21, 2016: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/27846053/inaccurate-self-report-of-height-and-its-impact-on-misclassification-of-body-mass-index-in-postmenopausal-women
#19
Xiaodan Mai, Jill N Sperrazza, Britt A Marshall, Kathleen M Hovey, Jean Wactawski-Wende
OBJECTIVE: Self-reported height is commonly used in population obesity research. Evidence has also shown a positive association between depression and obesity. We examined the extent of height misreporting and its impact on body mass index (BMI) calculations and classification, and explored whether depression is associated with height misreporting. METHODS: The Buffalo Osteoporosis and Periodontal Disease Follow-up Study enrolled 1,015 postmenopausal women between 2002 and 2006...
November 14, 2016: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/27846052/clusters-of-midlife-women-by-physical-activity-and-their-racial-ethnic-differences
#20
Eun-Ok Im, Young Ko, Eunice Chee, Wonshik Chee, Jun James Mao
OBJECTIVE: The purpose of this study was to identify clusters of midlife women by physical activity and to determine racial/ethnic differences in physical activities in each cluster. METHODS: This was a secondary analysis of the data from 542 women (157 non-Hispanic [NH] Whites, 127 Hispanics, 135 NH African Americans, and 123 NH Asian) in a larger Internet study on midlife women's attitudes toward physical activity. The instruments included the Barriers to Health Activities Scale, the Physical Activity Assessment Inventory, the Questions on Attitudes toward Physical Activity, Subjective Norm, Perceived Behavioral Control, and Behavioral Intention, and the Kaiser Physical Activity Survey...
November 14, 2016: Menopause: the Journal of the North American Menopause Society
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