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Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia

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https://www.readbyqxmd.com/read/27916439/adult-supratentorial-primitive-neuroectodermal-tumour-presenting-as-intracranial-haemorrhage-case-report
#1
Sean P Black-Tiong, Simon J I Sandler, Sophia Otto, Adam J Wells
Primitive neuroectodermal tumours (PNET) are highly malignant tumours with an aggressive clinical behaviour. Commonly seen in children, they are uncommon in the adult population, and rare in the supratentorial location. Adult supratentorial PNETs (ST-PNET) typically present with symptoms relating to raised intracranial pressure, seizures, or focal neurological deficits. Presentation with intracranial haemorrhage has been reported only twice before in the literature, one of which was fatal. We report the case of intracranial haemorrhage secondary to ST-PNET in a young adult and her immediate management...
December 1, 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/27914805/use-of-subdural-drain-for-chronic-subdural-haematoma-a-4-year-multi-centre-observational-study-of-302-cases
#2
David Yuen Chung Chan, Peter Yat Ming Woo, Calvin Hoi Kwan Mak, Alberto Chi Ho Chu, Charles Churk Hang Li, Natalie Man Wai Ko, Stephanie Chi Ping Ng, Tin Fung David Sun, Wai Sang Poon
Chronic subdural haematoma (CSDH) is a common neurosurgical condition and is more prevalent in the ageing population. Studies have suggested that placement of subdural drains after burr-hole drainage was associated with lower recurrence rates. However, a considerable proportion of surgeons remained unconvinced of the effectiveness of drain placement and concerns exist with the potential complications this additional manoeuvre entails such as infection or bleeding. The aim of the present study is to evaluate the impact of subdural drain on CSDH recurrence and its safety...
November 30, 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/27890544/persistent-hydrocephalus-due-to-postural-activation-of-a-ventricular-shunt-anti-gravity-device
#3
Claudia L Craven, Ahmed K Toma, Laurence D Watkins
The ever present need to balance over drainage with under drainage in hydrocephalus has required innovations including adjustable valves with antigravity devices. These are activated in the vertical position to prevent siphoning. We describe a group of bedridden patients who presented with unexplained under drainage caused by activation of antigravity shunt components produced by peculiar head/body position. Retrospective single centre case series of hydrocephalus patients, treated with ventriculo-peritoneal (VP) shunt insertion between April 2014 - February 2016...
November 24, 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/27887979/protective-effect-of-nicotinamide-adenine-dinucleotide-nad-against-spinal-cord-ischemia-reperfusion-injury-via-reducing-oxidative-stress-induced-neuronal-apoptosis
#4
Lei Xie, Zhenfei Wang, Changwei Li, Kai Yang, Yu Liang
As previous studies demonstrate that oxidative stress and apoptosis play crucial roles in ischemic pathogenesis and nicotinamide adenine dinucleotide (NAD(+)) treatment attenuates oxidative stress-induced cell death among primary neurons and astrocytes as well as significantly reduce cerebral ischemic injury in rats. We used a spinal cord ischemia injury (SCII) model in rats to verify our hypothesis that NAD(+) could ameliorate oxidative stress-induced neuronal apoptosis. Adult male rats were subjected to transient spinal cord ischemia for 60min, and different doses of NAD(+) were administered intraperitoneally immediately after the start of reperfusion...
November 23, 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/27887978/mild-encephalitis-encephalopathy-with-reversible-splenial-lesion-mers-due-to-dengue-virus
#5
Choong Yi Fong, Mi Mi Ko Khine, Alan Basil Peter, Wei Kang Lim, Faizatul Izza Rozalli, Kartini Rahmat
A 14-year-old girl presented with encephalopathy, delirium and ophthalmoplegia following a 3day history of high-grade fever. Brain MRI on day 6 of illness showed diffusion restricted ovoid lesion in the splenium of corpus callosum. Dengue virus encephalitis was diagnosed with positive PCR for dengue virus type-2 in both serum and cerebrospinal fluid. She made a complete recovery from day 10 of illness. Repeat brain MRI on day 12 of illness showed resolution of the splenial lesion. Serial diffusion tensor imaging (DTI) showed normal fractional anisotropy values on resolution of splenial lesion indicating that MERS was likely due to transient interstitial oedema with preservation of white matter tracts...
November 23, 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/27887977/direct-and-indirect-cost-of-myasthenia-gravis-a-prospective-study-from-a-tertiary-care-teaching-hospital-in-india
#6
Kamlesh Kumar Sonkar, Sanjeev Kumar Bhoi, Deepanshu Dubey, Jayantee Kalita, Usha Kant Misra
Myasthenia gravis (MG) requires lifelong treatment. The cost of management MG is very high in developed countries but there is no information on the cost of management of MG in the developing countries. This study reports the direct and indirect cost and predictors of cost of MG in a tertiary care teaching hospital in India. In a prospective hospital based study, from a tertiary hospital in India 66 consecutive patient during 2014-2015 were included. The age of the patients ranged between 6 and 75years. The severity of MG was assessed by myasthenia gravis foundation association (MGFA) class (MGFA) I-V...
November 23, 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/27887976/the-establishment-of-a-telestroke-service-using-multimodal-ct-imaging-decision-assistance-turning-on-the-fog-lights
#7
REVIEW
Jelle Demeestere, Claire Sewell, Jennifer Rudd, Timothy Ang, Louise Jordan, James Wills, Carlos Garcia-Esperon, Ferdinand Miteff, Venkatesh Krishnamurthy, Neil Spratt, Longting Lin, Andrew Bivard, Mark Parsons, Christopher Levi
Telestroke services have been shown to increase stroke therapy access in rural areas. The implementation of advanced CT imaging for patient assessment may improve patient selection and detection of stroke mimics in conjunction with telestroke. We implemented a telestroke service supported by multimodal CT imaging in a rural hospital in Australia. Over 21months we conducted an evaluation of service activation, thrombolysis rates and use of multimodal imaging to assess the feasibility of the service. Rates of symptomatic intracranial haemorrhage and 90-day modified Rankin Score were used as safety outcomes...
November 22, 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/27884604/surgical-management-of-falcine-meningiomas-experience-of-95-patients
#8
REVIEW
Domenico Murrone, Danilo De Paulis, Valerio di Norcia, Hambra Di Vitantonio, Renato Juan Galzio
Falcine meningiomas, defined as a meningiomas arising from the falx not involving the superior sagittal sinus, account for 9% of all intracranial meningiomas. We analyzed 95 patients with falcine meningiomas who underwent surgical removal of their lesion at our institution between 2001 and 2014. Surgical management of these patients, focusing on anatomical and clinical features is described. Thus, based on our series, a surgical algorithm, classifying the falcine meningioma into four types, according to location at the falx, and using an ipsilateral interhemispheric approach in supine or prone position, is described...
November 21, 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/27884603/cranial-nerve-involvement-in-charcot-marie-tooth-disease
#9
Nirav Das, Savannah Kandalaft, Xiao Wu, Ajay Malhotra
BACKGROUND: Charcot-Marie-Tooth Disease (CMT) is a rare disorder with less than 200,000 cases reported in the US every year, making diagnosis challenging. MR and CT imaging has become more common in the evaluation of CMT to identify areas of disease involvement. CASE REPORT: A 27-year-old female from Guatemala with a past history of polio initially presented to the emergency room for necrotizing pneumonia. MRI images demonstrated smoothly enlarged, mildly enhancing trigeminal nerves...
November 21, 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/27876186/randomized-trial-for-superiority-of-high-field-strength-intra-operative-magnetic-resonance-imaging-guided-resection-in-pituitary-surgery
#10
Vivek Tandon, Amol Raheja, Ashish Suri, P Sarat Chandra, Shashank S Kale, Rajinder Kumar, Ajay Garg, Mani Kalaivani, Ravindra M Pandey, Bhawani S Sharma
Till date there are no randomized trials to suggest the superiority of intra-operative magnetic resonance imaging (IOMRI) guided trans-sphenoidal pituitary resection over two dimensional fluoroscopic (2D-F) guided resections. We conducted this trial to establish the superiority of IOMRI in pituitary surgery. Primary objective was to compare extent of tumor resection between the two study arms. It was a prospective, randomized, outcome assessor and statistician blinded, two arm (A: IOMRI, n=25 and B: 2D-F, n=25), parallel group clinical trial...
November 18, 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/27865821/the-effects-of-tumor-treating-fields-and-temozolomide-in-mgmt-expressing-and-non-expressing-patient-derived-glioblastoma-cells
#11
Paul A Clark, Jordan T Gaal, Joslyn K Strebe, Cheri A Pasch, Dustin A Deming, John S Kuo, H Ian Robins
A recent Phase 3 study of newly diagnosed glioblastoma (GBM) demonstrated the addition of tumor treating fields (TTFields) to temozolomide (TMZ) after combined radiation/TMZ significantly increased survival and progression free survival. Preliminary data suggested benefit with both methylated and unmethylated O-6-methylguanine-DNA methyl-transferase (MGMT) promoter status. To date, however, there have been no studies to address the potential interactions of TTFields and TMZ. Thus, the effects of TTFields and TMZ were studied in vitro using patient-derived GBM stem-like cells (GSCs) including MGMT expressing (TMZ resistant: 12...
November 16, 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/27865820/adjacent-segment-disease-requiring-reoperation-in-cervical-total-disc-arthroplasty-a-literature-review-and-update
#12
REVIEW
Ki-Eun Chang, Martin H Pham, Patrick C Hsieh
OBJECTIVE: To evaluate the difference in rate of reoperation for adjacent segment disease (ASD) between anterior cervical decompression and fusion (ACDF) and total disc replacement (TDR). METHOD: A systematic review of literature was performed using PubMed, clinicaltrials.gov, and various other search engines. Nine studies met the inclusion criteria and were used to report an estimated overall rate of reoperation secondary to ASD for both ACDF and TDR. RESULTS: Forty-six clinical trials were identified after the initial search, and 9 studies met our inclusion criteria...
November 16, 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/27865819/buzz-juice-neurological-sequelae-of-synthetic-cannabinoids
#13
Manisha Kak, Fadi Mikhail, Sho T Yano, Rui Guan, Rimas V Lukas
The use of synthetic cannabinoids is becoming more widespread. Familiarity with the potential toxicities associated with these agents will grow in importance. We present a case of a woman who developed onset of confusion, visual hallucinations, and ataxia after vaporizing synthetic cannabinoids. MRI imaging demonstrated restricted diffusion and increased T2/FLAIR signal in the corpus callosum and cerebellar peduncles.
November 16, 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/27863972/vagus-nerve-stimulator-related-speech-exercise-induced-cough
#14
Charlotte Dandurand, Pierre-Olivier Champagne, Karim Elayoubi, Alexander G Weil, Paul Lespérence, Alain Bouthillier
Vagal nerve stimulation (VNS) therapy is an effective adjunctive treatment for chronic or recurrent treatment resistant depression. Although considered a safe procedure, increasing output current can be associated with stimulation induced side effects. We report the first case of dry cough induced by speech and mild exercise, occurring in the off mode following implantation of a vagal nerve stimulator (VNSor). We discuss the possible pathophysiology and the potential treatment options of this rare complication...
November 15, 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/27863971/systemic-inaccuracies-in-the-national-surgical-quality-improvement-program-database-implications-for-accuracy-and-validity-for-neurosurgery-outcomes-research
#15
John D Rolston, Seunggu J Han, Edward F Chang
The American College of Surgeons (ACS) National Surgical Quality Improvement Program (NSQIP) provides a rich database of North American surgical procedures and their complications. Yet no external source has validated the accuracy of the information within this database. Using records from the 2006 to 2013 NSQIP database, we used two methods to identify errors: (1) mismatches between the Current Procedural Terminology (CPT) code that was used to identify the surgical procedure, and the International Classification of Diseases (ICD-9) post-operative diagnosis: i...
November 15, 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/27863970/treatment-of-distal-anterior-cerebral-artery-aneurysms-with-the-pipeline-embolization-device
#16
Erez Nossek, Daniel W Zumofen, Avi Setton, Matthew B Potts, Eytan Raz, Maksim Shapiro, Howard A Riina, Maria Angeles De Miquel, David J Chalif, Peter K Nelson
Aneurysms of the anterior cerebral artery (ACA) located distal to the anterior communicating artery complex (ACOM) remain challenging to treat with surgical clip reconstruction as well as with endovascular coil-embolization strategies. We have treated five complex geometry distal ACA aneurysms with endoluminal reconstruction using the Pipeline Embolization Device (PED). Two aneurysms were of the dysplastic fusiform type. Three aneurysms were of complex saccular configuration. Three aneurysms were treated electively at the outset with PED...
November 15, 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/27847145/short-and-long-term-neurobehavioral-effects-of-lumbar-puncture-and-shunting-in-patients-with-malabsorptive-hydrocephalus-after-subarachnoid-haemorrhage-an-explorative-case-study
#17
Bernd-Otto Hütter, Joachim-Michael Gilsbach
BACKGROUND: The neuropsychological effects of lumbar puncture and shunting in terms of cognitive functioning and quality of life were analyzed prospectively in four patients with malabsorptive hydrocephalus who became symptomatic in the chronic state after aneurysmal subarachnoid haemorrhage (SAH). METHODS: A comprehensive battery of neuropsychological tests was applied to four patients before and shortly after lumbar puncture and six months later. In three of them a shunt has been inserted, one patient was treated by repeated lumbar punctures...
November 12, 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/27842796/extensive-bone-erosion-caused-by-pseudotumoral-aneurysm-growth
#18
Omer Doron, Jose E Cohen, Moshe Gomori, Sergey Spektor
Carotid ophthalmic aneurysms constitute 0.9-6.5% of the aneurysms of the ICA with up to 20% of the cases presenting with visual symptoms. We report a case of an adult woman, presented with chronic headaches and protracted visual alterations progressing to left eye amaurosis. Neuroradiological exams, revealed a giant partially thrombosed carotid ophthalmic aneurysm extending anteriorly, causing pseudotumoral spheno-orbital bone erosion. The patient underwent surgical clipping, evacuation of the thrombotic mass and decompression of the optic pathways with rapid recovery of the vision...
November 11, 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/27839916/lack-of-association-between-lrrk2-g2385r-and-cognitive-dysfunction-in-korean-patients-with-parkinson-s-disease
#19
Jeong Hoon Hong, Yue Kyung Kim, Jae Seol Park, Ji Eun Lee, Mi Sun Oh, Eun Joo Chung, Jeong-Yeon Kim, Young-Hee Sung, Chul Hyoung Lyoo, Jae Hyeok Lee, Do-Young Kwon, Hyun Sook Kim, Hae-Won Shin, Sun Ah Park, In-Seok Park, Joong-Seok Kim, Phil Hyu Lee, Seong-Beom Koh, Jong Sam Baik, Sang Jin Kim, Hyeo-Il Ma, Jae Woo Kim, Yun Joong Kim
Aside from the glucocerebrosidase gene, the genetic risk factors for cognitive decline in Parkinson's disease (PD) are controversial. We investigated whether the G2385R polymorphism in leucine-rich repeat kinase 2 gene (LRRK2), a risk variant for the development of PD in East Asians, is associated with cognitive dysfunction in PD. We recruited 299 PD patients, consisting of 23 carriers and 276 non-carriers of LRRK2 G2385R, from 14 centers. Global cognitive function was assessed using the Mini-Mental State Examination (MMSE) or the Montreal Cognitive Assessment (MoCA)...
November 10, 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/27839915/primary-spinal-intradural-extramedullary-lymphoma-a-novel-management-strategy
#20
Angelique Sao-Mai Do, Gabriel A Smith, Jonathan Pace, Alia Hdeib, Manish K Kasliwal
Primary spinal intradural extramedullary lymphoma remains a very rare entity in spinal oncology. In this case report, we present the first treatment of a PSIEL diagnosed by cytopathologic analysis alone followed by urgent radio- and chemotherapy in the literature. At 18-month follow-up, our patient was ambulatory with near total imaging resolution of the lesion. In conclusion, surgical excision or biopsy may not be necessary when suspicion for PSIEL exists, and may delay prompt medical and radiation treatment due to necessity for wound healing...
November 10, 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
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