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Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society

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https://www.readbyqxmd.com/read/29746371/bortezomib-associated-optic-atrophy-in-two-patients-with-multiple-myeloma
#1
Joseph G Chacko, Raed Behbehani, Kelsey N Hundley, Yazan Al-Fanek
No abstract text is available yet for this article.
May 8, 2018: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/29738350/congenital-third-nerve-palsy-associated-with-midbrain-hypoplasia-due-to-bilateral-segmental-internal-carotid-artery-agenesis
#2
Rebika Dhiman, Bhavya Gorimanipalli, Deepa R Swamy, Sanjay Sharma, Ajay Garg, Rohit Saxena
A 15-year-old girl, diagnosed with a partial right third nerve palsy, was found to have bilateral internal carotid artery agenesis. Neuroimaging with 3D-constructive interference in steady state scanning identified the possible etiology of the third nerve palsy as midbrain hypoplasia.
May 4, 2018: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/29697441/retrospective-multicenter-comparison-of-the-clinical-presentation-of-patients-presenting-with-diplopia-from-giant-cell-arteritis-vs-other-causes
#3
Ahmara G Ross, Imran Jivraj, Geoffrey Rodriguez, Maxwell Pistilli, John J Chen, Robert C Sergott, Mark Moster, Claire A Sheldon, Grant T Liu, Rod Foroozan, Melissa W Ko, Courtney E Francis, Zoë R Williams, Andrew G Lee, Collin M McClelland, Kenneth S Shindler, Sushma Yalamanchili, Benjamin Osborne, Thomas R Hedges, Gregory P Van Stavern, Ernest Puckett, Mohammed Rigi, Ignacia García-Basterra, Madhura A Tamhankar
BACKGROUND: Although giant cell arteritis (GCA) is a well-known cause of transient and permanent vision loss, diplopia as a presenting symptom of this condition is uncommon. We compared symptoms and signs of patients presenting with diplopia from GCA to those from other causes. METHODS: This was a multicenter, retrospective study comparing the clinical characteristics of patients presenting with diplopia from GCA with age-matched controls. Demographic information, review of symptoms, ophthalmic examination, and laboratory data of biopsy-proven patients with GCA were compared with those of age-matched controls presenting with diplopia...
April 24, 2018: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/29649006/the-influence-of-volume-and-anatomic-location-of-optic-disc-drusen-on-the-sensitivity-of-autofluorescence
#4
Frederik Cornelius Loft, Lasse Malmqvist, Anne-Sofie Wessel Lindberg, Steffen Hamann
BACKGROUND: Optic disc drusen (ODD) are acellular deposits in the optic nerve head. ODD can be diagnosed using different imaging modalities, including enhanced depth imaging optical coherence tomography (EDI-OCT) and autofluorescence (AF). It is unknown which factors determine the sensitivity of AF. The aim of this study was to investigate the effect of volume and anatomic location of ODD on the sensitivity of AF. METHODS: Cross-sectional study. RESULTS: A total of 38 patients (75 eyes) with ODD were included...
April 11, 2018: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/29613917/does-dolichoectasia-of-the-carotid-artery-cause-optic-neuropathy
#5
Valerie I Elmalem, Valerie A Purvin
No abstract text is available yet for this article.
April 2, 2018: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/29608536/eight-syndrome-horizontal-gaze-palsy-plus-ipsilateral-seventh-nerve-palsy
#6
Kemar E Green, David P W Rastall, Eric R Eggenberger
A 62-year-old woman developed a right horizontal gaze palsy and ipsilateral facial nerve palsy due to a right pontine tegmentum infarct. This constitutes a forme fruste of the eight-and-a-half syndrome that we have termed the eight syndrome.
March 30, 2018: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/29608535/genetic-survey-of-adult-onset-idiopathic-intracranial-hypertension
#7
Markus H Kuehn, Rajashree Mishra, Benjamin E Deonovic, Kimberly N Miller, Shana E McCormack, Grant T Liu, Mark J Kupersmith, Michael Wall
BACKGROUND: Idiopathic intracranial hypertension (IIH) is a condition characterized by increased intracranial pressure of unknown cause. IIH has been shown to be associated with female sex as well as obesity. This genome-wide association study was performed to determine whether genetic variants are associated with this condition. METHODS: We analyzed the chromosomal DNA of 95 patients with IIH enrolled in the Idiopathic Intracranial Hypertension Treatment Trial and 95 controls matched on sex, body mass index, and self-reported ethnicity...
March 30, 2018: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/29595558/ocular-motor-dysfunction-due-to-brainstem-disorders
#8
Michael S Vaphiades
No abstract text is available yet for this article.
March 27, 2018: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/29561328/multiple-sclerosis-b-cells-take-center-stage
#9
Anne-Katrin Pröbstel, Stephen L Hauser
No abstract text is available yet for this article.
March 20, 2018: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/29561327/congenital-achiasma
#10
Augustin Lecler, Arnaud Attye, Catherine Edelson
In evaluating a 3-month-old boy with horizontal nystagmus, brain MRI revealed absence of the optic chiasm. The remainder of the brain was normal in appearance. Achiasma was confirmed with diffusion tensor imaging and best visualized with optimized probabilistic-based tractography.
March 20, 2018: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/29554002/cerebrospinal-fluid-pressure-reduction-results-in-dynamic-changes-in-optic-nerve-angle-on-magnetic-resonance-imaging
#11
Ranliang Hu, John Holbrook, Nancy J Newman, Valerie Biousse, Beau B Bruce, Deqiang Qiu, John Oshinski, Amit M Saindane
BACKGROUND: Optic nerve sheath tortuosity is a previously reported, but incompletely characterized, finding in idiopathic intracranial hypertension (IIH). We hypothesized that optic nerve angle (ONA), as a quantitative measure of tortuosity, would change dynamically with cerebrospinal fluid (CSF) pressure status of patients with IIH immediately before and after lumbar puncture (LP). METHODS: Consecutive patients with suspected IIH referred for MRI and diagnostic LP were prospectively enrolled in this single institution, institutional review board-approved study...
March 16, 2018: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/29554001/visual-outcomes-and-clinical-manifestations-of-pediatric-optic-neuritis-in-indian-population-an-institutional-study
#12
Selvakumar Ambika, Krishnakumar Padmalakshmi, Viswanathan Venkatraman, Olma V Noronha
BACKGROUND: Optic neuritis in children is an uncommon disorder which usually occurs after a viral illness or vaccination and, less frequently, occurs as a manifestation of a demyelinating disorder. Pediatric optic neuritis usually is bilateral and presents with optic disc edema, recovers rapidly with steroid therapy, and generally has low conversion rate to multiple sclerosis or neuromyelitis optica spectrum disorder. We report the clinical features and treatment outcomes of pediatric optic neuritis in Indian population, for which little data are available...
March 16, 2018: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/29554000/evaluation-of-vision-related-quality-of-life-in-chinese-patients-with-leber-hereditary-optic-neuropathy-and-the-g11778a-mutation
#13
Shilei Cui, Hanqiu Jiang, Jingting Peng, Jiawei Wang, Xiaojun Zhang
OBJECTIVE: To assess quality of life (QoL) measures in Chinese Leber hereditary optic neuropathy (LHON) patients with the G11778A mutation. METHODS: Chinese LHON patients with the G11778A mutation were prospectively evaluated using the Visual Function Index (VF-14) at 6 months, 1 year, and 3 years after the involvement of the second eye. Patients who completed the VF-14 at all 3 follow-up time designations were included in the analysis. RESULTS: Fifty-five patients met the inclusion criteria...
March 16, 2018: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/29521709/intravitreal-triamcinolone-acetonide-injection-in-a-rodent-model-of-anterior-ischemic-optic-neuropathy
#14
Luciano S Pereira, Marcos P Ávila, Luciana X Salustiano, Alcio C Paula, Emmanuel Arnhold, Timothy J McCulley
INTRODUCTION: The management of nonarteritic anterior ischemic optic neuropathy centers around prevention of second eye involvement, without a uniformly accepted therapy for the involved eye. Several researchers have assessed the benefit of steroids with conflicting results. This experimental study was designed to evaluate the efficacy of a single intravitreal triamcinolone acetonide injection (IVTA) in preserving retinal ganglion cells (RGCs) in a rodent model of anterior ischemic optic neuropathy (rAION)...
March 6, 2018: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/29750736/multiple-sclerosis-therapy-are-we-ready-for-a-one-size-fits-all-approach
#15
Bruce A C Cree
No abstract text is available yet for this article.
June 2018: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/29750735/the-shifting-landscape-of-disease-modifying-therapies-for-relapsing-multiple-sclerosis
#16
Jodie M Burton, Mark S Freedman
BACKGROUND: Multiple sclerosis (MS) is the most common nontraumatic neurological disorder of young adults, and roughly 85% of patients present with the relapsing form of the disease. Over the past 2 decades, the treatment arsenal for relapsing MS has expanded and evolved from mildly effective and relatively benign injectable agents to potent cell-depleting monoclonal agents. The latter have the potential to achieve disease remission coupled with risk of moderate to severe adverse events with which all MS care providers will need to acquaint themselves...
June 2018: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/29750734/evolution-of-visual-outcomes-in-clinical-trials-for-multiple-sclerosis-disease-modifying-therapies
#17
Rachel C Nolan, Omar Akhand, John-Ross Rizzo, Steven L Galetta, Laura J Balcer
: BACKGROUND:: The visual pathways are increasingly recognized as an ideal model to study neurodegeneration in multiple sclerosis (MS). Low-contrast letter acuity (LCLA) and optical coherence tomography (OCT) are validated measures of function and structure in MS. In fact, LCLA was the topic of a recent review by the Multiple Sclerosis Outcome Assessments Consortium (MSOAC) to qualify this visual measure as a primary or secondary clinical trial endpoint with the Food and Drug Administration (FDA) and other regulatory agencies...
June 2018: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/29750733/vision-rehabilitation
#18
August Colenbrander, Donald C Fletcher
No abstract text is available yet for this article.
June 2018: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/29742521/literature-commentary
#19
(no author information available yet)
In this issue of Journal of Neuro-Ophthalmology, M. Tariq Bhatti, MD and Mark L. Moster, MD will discuss the following 6 articles.
June 2018: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/29738351/more-than-meets-the-eye-the-eye-and-migraine-what-you-need-to-know
#20
Kathleen B Digre
Migraine has long been associated with disturbances of vision, especially migraine with aura. However, the eye plays an important role in sensory processing as well. We have found that the visual quality of life is reduced in migraine. In this review, we discuss how the migraine and eye pain pathways are similar and affect many of the common complaints which are seen in ophthalmology and neuro-ophthalmology offices, such as dry eye and postoperative eye pain. We also review other related phenomena, including visual snow and photophobia, which also are related to altered sensory processing in migraine...
June 2018: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
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