Nader Tanideh, Mohammad Ali Behnam, Sheida Mohit Ghiri, Omid Koohi-Hosseinabadi, Hossein Khajeh-Zadeh, Shahrokh Zare, Negar Azarpira, Armin Akbarzadeh, Soheil Ashkani-Esfahani, Alireza Ebrahimi, Adrina Habibzadeh
BACKGROUND: Mesenchymal stem cell (MSC) injection has emerged as a novel treatment for knee osteoarthritis (OA). In addition, low-level laser therapy (LLLT) has been reported to delay the progression of OA. Thus, the current study on animal models of OA investigated the effectiveness of these methods when administered independently and combined. METHODS: Twenty-five guinea pig models of OA were randomly sorted into five study groups. The test groups received intra-articular MSC, LLLT, and a combination of these therapeutics for 8 weeks...
February 28, 2024: Knee