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Pakistan Journal of Pharmaceutical Sciences

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https://www.readbyqxmd.com/read/29737304/therapeutic-effects-of-statins-drugs-use-and-continuous-nursing-on-patients-with-chronic-obstructive-pulmonary-disease-and-the-influence-of-life-quality
#1
Ju Weina, Liu Yanhua, Wang Jian, Shao Yan
Chronic obstructive pulmonary disease (COPD) is able to be treated and delayed. Many interventions include smoking cessation and daily maintenance of drug therapy. In clinical practice, although respiratory physicians have given optimal drug treatment to patients, there is no treatment for etiological factors in these treatments, and they have little effect on the long-term prognosis of COPD. Therefore, this paper puts forward a method of continuing care. Through Meta analysis of the therapeutic effects of statins, it is shown that statins have a positive impact on the treatment of chronic obstructive pulmonary disease...
May 2018: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29737303/curative-effect-of-oral-ulcer-powder-on-the-treatment-of-recurrent-aphthous-ulcer
#2
Shenshan Zhu, Qiaoyun Shi, Jian Lu
Recurrent aphthous ulcer (RAU) is a common and frequently occurring disease in the Department of Stomatology. The clinical manifestations are localized ulcer of oral mucosa, and the ulcer mask is self limiting and easy to recur. In this paper, by adopting the randomized study method, the author study the effect of oral ulcer powder combined with traditional Chinese drugs on patients with recurrent aphthous ulcer, and analyze its effect on inflammatory factor. Kangfuxin liquid combined with oral ulcer powder helps reduce recurrent aphthous ulcer patients the levels of inflammatory factors, improve the symptoms of pain...
May 2018: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29737302/drug-effect-of-atorvastatin-on-middle-cerebral-atherosclerotic-stenosis-and-high-resolution-nmr-diagnosis
#3
Xingchi Chen, Sainan Wang, Lulu Lin, Yu Li, Hui Zhang
Atherosclerosis (AS) is a chronic inflammatory reaction with the pathological changes in the lipid deposition of arterial intima. The disorder of blood lipid metabolism is the main factor of the occurrence and development of AS, and the inflammatory reaction and autoimmune reaction also run through the development of AS. In this study, we compared the efficacy and safety of atorvastatin, simvastatin, pravastatin and rosuvastatin in the treatment of AS. At the same time, we used high resolution magnetic resonance imaging (MRI) to assess the changes in plaque area in the middle cerebral artery and the patch area before and after drug treatment...
May 2018: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29737301/flurbiprofen-axetil-analgesic-effect-and-adverse-reaction
#4
Xiaodong Zhao, Leting Ji
Flurbiprofen axetil is a targeted analgesic and non steroidal analgesic with lipid microspheres as drug carrier. It can selectively accumulate in surgical incision and reduce the allodynia a caused by surgical trauma. In this paper, the experimental subjects were divided into three groups to analyze the difference in the analgesic effect of different doses of flurbiprofen axetil for postoperative analgesia. The patients in group A, B and C were treated with flurbiprofen axetil injection 100, 150, 200mg, respectively...
May 2018: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29737300/effect-of-laparoscopy-combined-with-mifepristone-in-the-treatment-of-endometriosis-and-drug-reaction-analysis
#5
Jing Li, Huilin Yang, Jie Song
Endometriosis is a common benign disease of Gynecology, which often causes symptoms of dysmenorrhea, pelvic pain and infertility. In this paper, we analyzed the effect of laparoscopy combined with mifepristone in the treatment of endometriosis. By observing the clinical efficacy and side effects of small dose mifepristone, we explored the feasibility of small dose mifepristone in the treatment of recurrent endometriosis. The results showed that the clinical symptoms of small dose mifepristone group and danazol group were improved to varying degrees...
May 2018: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29737299/intervention-and-effect-analysis-of-achyranthes-bidentata-blume-combined-with-aerobic-exercise-to-interfere-with-type-2-diabetes
#6
Chi Ma, Chengtao Zhang, Xin Li
With the continuous progress of traditional Chinese medicine extraction technology in recent years, the active components of traditional Chinese medicine have been continuously extracted and analyzed. In this paper, the authors studied the effect of aerobic exercise combined with the extract of the Achyranthes bidentata on the serum indexes of T2DM rats. Through systematic analysis of measurement indexes of Chinese medicine treatment group, we found that all indexes of FPG, INS, NOXs, ROS and SOD all showed a marked improvement, which fully proved the effect of Achyranthes bidentata extract on improving the condition of rats with type 2 diabetes mellitus...
May 2018: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29737298/a-preliminary-study-on-the-anticancer-efficacy-of-caulis-spatholobi-compound-1802
#7
Yingnan Cao, Qiling Tang, Lan Luo, Ziying Gao, Suzhong Zhang
In recent years, antitumor and antiviral effect of Caulis spatholobi becomes a hot topic of medical drug research. Experiment shows that the water extract of Caulis spatholobi compound 1802 showed the effect of inhibiting tumor growth, the difference was statistically significant (P<0.05); the rate of tumor inhibition was highest in the high dose group of compound 1802, which could reach 41.99%. Anti tumor drugs generally have high toxicity, therefore, low toxicity is the significant characteristic of Caulis spatholobi...
May 2018: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29737297/effect-of-anti-bacterials-on-wound-healing-after-surgery-in-ophthalmology-and-drug-effect-analysis
#8
Zhai Juntao, Duan Duwen, Wang Xiufang, Zhang Shihua
At present, most hospitals in China have the phenomenon of abuse of antibiotics. Hospitals usually give antibiotics to patients, so as to prevent infection after operation. But the use of a large number of antibiotics can cause the patient to produce antibodies to the antibacterials and reduce the sensitivity of the pathogen to the antimicrobial agents. The author studied the application of antibacterial drugs in ophthalmological surgery and carried out a comparative analysis. The total effective rate of the experimental group was 92...
May 2018: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29737296/adverse-reactions-analysis-and-prevention-of-antiseptic-drug-in-the-obstetrics-and-gynecology-nursing
#9
Yongli Wang, Qing Bo, Ying Zhang, Jing He
Antimicrobial agents are widely used in gynecologic inflammation and surgical period, so as to cure some infectious diseases, reduce the chance of surgical incision infection, but at the same time, there are many adverse reactions. The use of nursing interventions in obstetrics and gynecology can significantly reduce the adverse drug reactions in the treatment. The results showed that the incidence of adverse reactions in the observation group was 8.8%, while that in the control group was 15.6%. The incidence of adverse reactions in the observation group was significantly lower than that in the control group (P<0...
May 2018: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29737295/anticoagulant-effects-of-rivaroxaban-after-surgical-fixation-of-spinal-fracture
#10
Liang Chunhong, Lv Jin, Zhang Qin, Xie Guohui
In recent years, the concept of treatment after surgery in the department of orthopedics has changed from hemostasis to anticoagulant. This article analyses the safety and effectiveness of anticoagulants for prophylactic anticoagulants after spinal fractures. By analyzing the incidence of bleeding and VTE in 2 weeks after operation, there was no significant difference between the 2 groups (P>0.05), but the incidence of VTE in rivaroxaban group was significantly lower than that in control group. In conclusion, the rivaroxaban oral anticoagulants are stable, safe and easy to use...
May 2018: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29737294/effect-of-anthracycline-combined-with-aerobic-exercise-on-the-treatment-of-breast-cancer
#11
Zhijun Ma
Anthracycline is a standard drug for the treatment of breast cancer. However, anthracycline has great cardiotoxicity. Some patients stop chemotherapy during severe chemotherapy and even undergo serious heart failure. At the same time, there is lack of clinical study on whether aerobic exercise can reduce the cardiotoxicity of chemotherapy drugs. The purpose of this study is to investigate the effects of aerobic exercise on the cardiac function of patients with breast cancer after anthracycline therapy. The results showed that the control group LVEF decreased significantly...
May 2018: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29737293/effect-of-sedative-drugs-with-vitamin-b6-combined-with-other-b-vitamins-in-the-anti-stress-of-captive-amur-tiger
#12
Qiao Zhenglei, Ma Jianzhang
In order to reduce the stress response of animals in animal transportation, it is often used to feed the animals with sedative drugs combined with compound vitamin B. In this article, we will randomly divide 16 amur tiger into the control group and the experimental group. The drug intervention is carried out in the experimental group. The sedative is mainly dexmedetomidine, combined with compound vitamin B, while control group did not feed the drug. The urine of two groups of individuals was collected before and after transportation and the cortisol content in urine was determined by radioimmunoassay as an indication of stress...
May 2018: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29737292/analysis-of-curative-effect-of-fluoxetine-and-escitalopram-in-the-depression-treatment-based-on-clinical-observation
#13
Zhang Xiaoling, Han Yunping, Lian Yingdong
Depression is a common affective disorder or mood disorder, which seriously affects people's physical and mental health and the quality of life. This study compared efficacy of escitalopram and fluoxetine on depression patients, and analyzed the inflammatory factors, serum homocysteine (Hcy) levels and the effects of adverse reactions, so as to provide reference for the clinical. The results showed that the total effective rate of the observation group (90.7%) was higher than that of the control group (80%), but the difference was not statistically significant (p>0...
May 2018: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29737291/rational-selection-of-antibacterial-drugs-and-postoperative-nursing-for-gynecologic-and-obstetric-surgery-patients
#14
Li Hou, Yan Zhang, Yan Luan, Beibei Xin, Chunxia Wang
Infection after gynecologic surgery is very common and frequent. If the control is not good, it will lead to serious consequences. Therefore, it is necessary to use antibiotics in the period of obstetrics and gynecology. This study will explore the use of antimicrobial agents in gynecologic and obstetric surgery, thus standardizing the use of antibiotics in the process of obstetrics and gynecology. Through the analysis of the use of antibacterials, we can see that the highest utilization rate of 5 kinds of antibacterial drugs followed by Cefaclor Sustained Release Tablets (65...
May 2018: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29737290/pharmacoeconomic-evaluation-of-glimepiride-combined-with-other-drugs-in-the-treatment-of-diabetes
#15
Xiufang Liu, Liping Zeng, Wenchao Xu
The goal of diabetic drug treatment is to stabilize the blood sugar for a long time to close to the normal level, to correct the metabolic disorder and eliminate the symptoms. At present, glimepiride has become commonly used drugs for the treatment of diabetes with obesity. Compared with metformin, acarbose and rosiglitazone, glimepiride has different mechanisms of drug action, clinical combination showed synergistic hypoglycemic effect, good clinical curative effect. So, we use three treatments to study as group A (glimepiride and metformin); group B (glimepiride and acarbose); Group C (glimepiride and rosiglitazone)...
May 2018: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29737289/observation-for-clinical-effect-of-phellodendron-wet-compress-in-treating-the-phlebitis-caused-by-infusion
#16
Ying Wan
Aim of the study was to observe and analyze the clinical effect of phellodendron wet compress in treating the phlebitis caused by infusion. The research objects were 600 cases of phlebitis caused by infusion, all of which were treated in our hospital from June 2013 to June 2016. All patients were entitled to the right to know. They were randomly divided into the research group and the control group. Patients in the control group were treated with magnesium sulfate solution wet compress, while patients in the research group were treated with phellodendron wet compress...
May 2018: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29737288/effect-of-different-types-of-anticoagulants-in-the-prevention-of-venous-thrombosis-in-the-operation-of-knee-joint-bone-operation
#17
Wensheng Xu, Tao Zhang, Zenghua Yang, Lin Nie
Deep venous thrombosis is one of the common complications after major surgery in the Department of Orthopedics. The selective knee replacement of the lower extremities is more likely to cause the occurrence of DVT. The most commonly used anticoagulants in the Department of Orthopedics now include low molecular weight heparin (LMWH), Rivaroxaban, ordinary heparin, aspirin and warfarin. At present, the clinical application of low molecular weight heparin is the most, and the effect is the most accurate. This study compared the efficacy and safety of three commonly used anticoagulants such as aspirin, LMWH and Rivaroxaban in preventing VTE after hip and knee arthroplasty, so as to provide a theoretical basis for selecting suitable anticoagulant drugs in clinic...
May 2018: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29735471/therapeutic-effects-of-statins-drugs-use-and-continuous-nursing-on-patients-with-chronic-obstructive-pulmonary-disease-and-the-influence-of-life-quality
#18
Ju Weina, Liu Yanhua, Wang Jian, Shao Yan
Chronic obstructive pulmonary disease (COPD) is able to be treated and delayed. Many interventions include smoking cessation and daily maintenance of drug therapy. In clinical practice, although respiratory physicians have given optimal drug treatment to patients, there is no treatment for etiological factors in these treatments, and they have little effect on the long-term prognosis of COPD. Therefore, this paper puts forward a method of continuing care. Through Meta analysis of the therapeutic effects of statins, it is shown that statins have a positive impact on the treatment of chronic obstructive pulmonary disease...
May 2018: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29735470/curative-effect-of-oral-ulcer-powder-on-the-treatment-of-recurrent-aphthous-ulcer
#19
Shenshan Zhu, Qiaoyun Shi, Jian Lu
Recurrent aphthous ulcer (RAU) is a common and frequently occurring disease in the Department of Stomatology. The clinical manifestations are localized ulcer of oral mucosa, and the ulcer mask is self limiting and easy to recur. In this paper, by adopting the randomized study method, the author study the effect of oral ulcer powder combined with traditional Chinese drugs on patients with recurrent aphthous ulcer, and analyze its effect on inflammatory factor. Kangfuxin liquid combined with oral ulcer powder helps reduce recurrent aphthous ulcer patients the levels of inflammatory factors, improve the symptoms of pain...
May 2018: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29735469/drug-effect-of-atorvastatin-on-middle-cerebral-atherosclerotic-stenosis-and-high-resolution-nmr-diagnosis
#20
Xingchi Chen, Sainan Wang, Lulu Lin, Yu Li, Hui Zhang
Atherosclerosis (AS) is a chronic inflammatory reaction with the pathological changes in the lipid deposition of arterial intima. The disorder of blood lipid metabolism is the main factor of the occurrence and development of AS, and the inflammatory reaction and autoimmune reaction also run through the development of AS. In this study, we compared the efficacy and safety of atorvastatin, simvastatin, pravastatin and rosuvastatin in the treatment of AS. At the same time, we used high resolution magnetic resonance imaging (MRI) to assess the changes in plaque area in the middle cerebral artery and the patch area before and after drug treatment...
May 2018: Pakistan Journal of Pharmaceutical Sciences
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