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Veterinary Dermatology

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https://www.readbyqxmd.com/read/28439997/therapeutic-effectiveness-of-calcineurin-inhibitors-in-canine-vesicular-cutaneous-lupus-erythematosus
#1
Frane Banovic, David Robson, Monika Linek, Thierry Olivry
BACKGROUND: Oral and topical calcineurin inhibitors (CIs) have been reported to lead to complete lesion remission in several dogs with vesicular cutaneous lupus erythematosus (VCLE). OBJECTIVES: To report retrospectively on the effectiveness and adverse effects of systemic (ciclosporin) and/or topical (tacrolimus/pimecrolimus) CIs in 11 dogs with VCLE. METHODS: Inclusion criteria were: (i) presence of characteristic annular, polycyclic or serpiginous ulcerations distributed over the groin, axillae and/or ventral abdomen; (ii) a histopathological diagnosis of VCLE (i...
April 24, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28439995/scleromyxoedema-in-a-dog
#2
Aurore F Laprais, Petra Bizikova, Erin W Lashnits, Alison Tucker, Keith E Linder
BACKGROUND: In humans, scleromyxoedema is a chronic progressive skin condition traditionally characterized by deposits of mucin, increased number of fibroblasts and fibrosis in the skin, and by systemic disease. Thyroid disease is typically absent. A monoclonal gammopathy is usually present, as are other comorbidities. Descriptions of scleromyxoedema in the veterinary literature are limited to a single feline case. One dog, previously reported as having papular mucinosis, exhibited features that matched the more current diagnostic criteria of scleromyxoedema...
April 24, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28393458/increased-filaggrin-metabolizing-enzyme-activity-in-atopic-skin-a-pilot-study-using-a-canine-model-of-atopic-dermatitis
#3
Natalia Fanton, Domenico Santoro, Luisa Cornegliani, Rosanna Marsella
BACKGROUND: Filaggrin (FLG) and its metabolites are essential for skin barrier function and hydration of the stratum corneum. Alteration of the FLG metabolism could be the basis for an abnormal skin barrier in allergic dogs. OBJECTIVES: To investigate the expression and distribution of calpain-1, caspase-14, furin and matriptase, four enzymes involved in FLG metabolism, in the skin of atopic and healthy beagles. METHODS: Skin biopsies were collected from four healthy and four atopic beagles before and after allergen exposure...
April 9, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28386956/comparison-of-cellular-location-and-expression-of-plakophilin-2-in-epidermal-cells-from-nonlesional-atopic-skin-and-healthy-skin-in-german-shepherd-dogs
#4
Brita Ardesjö-Lundgren, Katarina Tengvall, Kerstin Bergvall, Fabiana H G Farias, Liya Wang, Åke Hedhammar, Kerstin Lindblad-Toh, Göran Andersson
BACKGROUND: Canine atopic dermatitis (CAD) is an inflammatory and pruritic allergic skin disease caused by interactions between genetic and environmental factors. Previously, a genome-wide significant risk locus on canine chromosome 27 for CAD was identified in German shepherd dogs (GSDs) and Plakophilin-2 (PKP2) was defined as the top candidate gene. PKP2 constitutes a crucial component of desmosomes and also is important in signalling, metabolic and transcriptional activities. OBJECTIVES: The main objective was to evaluate the role of PKP2 in CAD by investigating PKP2 expression and desmosome structure in nonlesional skin from CAD-affected (carrying the top GWAS SNP risk allele) and healthy GSDs...
April 6, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28386939/should-precision-medicine-be-encouraged-in-veterinary-dermatology
#5
LETTER
Ramón M Almela, Wolfgang Bäumer
No abstract text is available yet for this article.
April 6, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28378419/successful-treatment-of-pemphigus-foliaceus-in-a-berrichon-du-cher-ram-with-methylprednisolone-acetate
#6
Bianca Lambacher, Julia Schoiswohl, Rene Brunthaler, Thomas Wittek, Reinhild Krametter-Frötscher
BACKGROUND: Pemphigus foliaceus is a severe, autoimmune blistering skin disease, which is described in humans and some animal species. In small ruminants pemphigus foliaceus has rarely been described and, to the best of the authors' knowledge, little information is available about successful treatment in sheep. AIM: This case report describes a Berrichon du Cher ram with the presumed diagnosis of pemphigus foliaceus. METHODS: The ram was treated with methylprednisolone acetate 40 mg at a dosage of 2...
April 4, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28370574/two-cutaneous-horns-associated-with-canine-papillomavirus-type-1-infection-in-a-pit-bull-dog
#7
LETTER
Elizabeth Falk, Christian E Lange, Sammuel Jennings, Lluis Ferrer
No abstract text is available yet for this article.
April 2, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28345791/trichoscopic-diagnosis-of-cutaneous-pelodera-strongyloides-infestation-in-a-dog
#8
Rareş G M Căpitan, Chiara Noli
BACKGROUND: Pelodera strongyloides infestation has rarely been reported in dogs. It is a saprophytic free-living nematode, found in moist decaying organic matter, whose L3 larval stages occasionally can invade the skin of dogs and humans. Larvae penetrate the follicular infundibula causing an erythematous and pruritic dermatitis. The disease is usually diagnosed by deep skin scraping or histopathology, with large numbers of parasites readily identified in hair follicles. CASE REPORT: Pelodera strongyloides dermatitis was diagnosed in a six-year-old mixed breed dog presenting with alopecia, erythema and severe pruritus on the ventrum and limbs...
March 27, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28337800/mycoplasma-infection-of-the-middle-ear-in-three-cats
#9
Amanda L Ackermann, Jennifer Ann Lenz, Elizabeth R May, Linda A Frank
BACKGROUND: Mycoplasma spp. are commensal organisms found in association with the mucus membranes of all mammalian species and are implicated in bacterial infections of many different locations. Mycoplasma spp. as a primary pathogen associated with otitis media in cats has not been reported. OBJECTIVES: To describe three cats with Mycoplasma infection of the middle ear associated with various underlying disease processes. ANIMALS: Three client-owned cats...
March 23, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28317209/the-effects-of-cryopreservation-on-the-expression-of-canine-regulatory-t-cell-markers
#10
Noemi Tarpataki, Marcin Wawrzyniak, Cezmi A Akdis, Beate Rückert, Marina L Meli, Nina M Fischer, Claude Favrot, Ana Rostaher
BACKGROUND: Regulatory T (Treg) cells have been described as key regulators in various immunological processes and are of growing interest in veterinary allergy. Cryopreservation of immune cells is performed routinely in human basic science research and in clinical studies. As such, it allows batch testing of collected samples at a single time point, resulting in a significant reduction in sample variability. Data which describe the effects of cryopreservation on Treg cell frequency and functionality in the canine species are important to inform future research...
March 19, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28295766/impact-of-a-terbinafine-florfenicol-betamethasone-acetate-otic-gel-on-the-quality-of-life-of-dogs-with-acute-otitis-externa-and-their-owners
#11
Chiara Noli, Roberta Sartori, Tiziana Cena
BACKGROUND: Treatment of canine otitis externa with owner-administered products can be difficult. OBJECTIVES: To evaluate otic treatment administered by a veterinarian on quality of life (QoL) of dogs with otitis externa and their owners, and on clinical and cytology parameters of otitis; compared to an owner-administered treatment. ANIMALS: Fifty client-owned dogs randomly randomized into two groups and treated for 2 weeks. METHODS: Veterinarians treated Group A dogs with a veterinary licensed otic gel on two occasions at a 1 week interval; owners treated Group B dogs once daily with a veterinary licensed otic drop based product along with twice weekly cleaning...
March 15, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28261924/the-effect-of-a-herbal-paste-and-oil-extract-on-the-lipid-content-of-canine-hair-fibres
#12
Yutaka Momota, Kenichiro Shimada, Chihiro Kadoya, Azusa Gin, Jun Kobayashi, Yuka Nakamura, Takako Matsubara, Toshinori Sako
BACKGROUND: Application of herbal paste and oil to a dog's coat and body before rinsing (often combining with shampooing) is a cosmetic therapy available in Japan. It is highly appreciated by users, who claim that the treatment makes the coat shinier, improves volume and eliminates tangles. However, there has been no scientific evaluation of such treatments. HYPOTHESIS/OBJECTIVES: Improvement of hair condition is derived from oils such as sebum and conditioning oils because chemicals are not used...
March 6, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28251703/in-vitro-susceptibility-testing-of-malassezia-pachydermatis-to-gentamicin
#13
Freddy A Silva, Otilia Ferrer, Soraya Déniz, Inmaculada Rosario, Magnolia Conde-Felipe, Esther L Díaz, Begoña Acosta-Hernández
BACKGROUND: Two studies have observed that growth media containing gentamicin can inhibit the growth of the yeast organism Malassezia pachydermatis. The minimum inhibitory concentration (MIC) of this bactericidal antibiotic for this organism has not been previously determined. OBJECTIVE: To evaluate the susceptibility of M. pachydermatis isolates to gentamicin. METHODS: The MIC of gentamicin was determined using a modified version of the M27-A3 microdilution method following the guidelines of the Clinical and Laboratory Standards Institute...
March 2, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28251698/use-of-oral-fluralaner-for-the-treatment-of-psoroptes-cuniculi-in-15-naturally-infested-rabbits
#14
Galia Sheinberg, Camilo Romero, Rafael Heredia, Miguel Capulin, Enrique Yarto, Juan Carpio
BACKGROUND: Psoroptes cuniculi, a nonburrowing ear mite, is a common ectoparasite of rabbits. Constant irritation of the auditory canal by the presence of this mite can lead to otitis externa or otoacariasis. OBJECTIVE: The goal of this study was to evaluate the effect of fluralaner on rabbits naturally infested with P. cuniculi and exhibiting clinical signs. ANIMALS: Fifteen female New Zealand domestic rabbits with otitis due to naturally occurring infestation with P...
March 1, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28247445/detection-of-dna-from-undeclared-animal-species-in-commercial-elimination-diets-for-dogs-using-pcr
#15
Christa Horvath-Ungerboeck, Karoline Widmann, Stefanie Handl
BACKGROUND: Elimination diets are the gold standard for the diagnosis of adverse food reactions (AFR). A broad variety of commercial diets are available containing either hydrolysed protein or novel ingredients which claim to be suitable for elimination diets. Contamination may be one factor accounting for the failure of commercial elimination diet trials. HYPOTHESIS/OBJECTIVES: To test commercial diets labelled as suitable for elimination diets for dogs, for DNA of animal origin other than that declared on the label...
February 28, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28220545/the-effects-of-a-topical-lipid-complex-therapy-on-dogs-with-atopic-dermatitis-a-double-blind-randomized-placebo-controlled-study
#16
Stefan Hobi, Christoph Klinger, Janine Classen, Ralf S Mueller
BACKGROUND: Canine atopic dermatitis is a common clinical presentation. The skin barrier seems to play a fundamental role in the pathogenesis. Therefore a topical spot-on product containing a mixture of lipids may improve clinical signs without adverse effects if it were to improve stratum corneum barrier function. ANIMALS: Twenty six privately owned atopic dogs of different breed, age, gender and weight were included in a double blind, randomized, placebo-controlled study...
February 20, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28185331/follicular-lipidosis-in-a-dachshund-dog
#17
Marcia M Colodel, Bruno Pietroluongo, Ronaldo Lucas, Kenia B Gomes, Fabrizio Grandi
BACKGROUND: Follicular lipidosis is a rare disease, having only been reported in six Rottweiler dogs. The diagnosis of follicular lipidosis is confirmed by histopathological examination of the affected skin. OBJECTIVE: To report a case of follicular lipidosis in a dachshund dog. ANIMALS: A 13-month-old female dachshund dog, with hypotrichosis on the head and cervical region from 10 months of age. METHODS: Histological examination of skin biopsy specimens...
February 10, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28164401/skin-depigmentation-associated-with-toceranib-phosphate-in-a-dog
#18
Jacqueline V J Cavalcanti, Andrea Hasbach, Katie Barnes, Rahul B Dange, Jon Patterson, Paulo Vilar Saavedra
BACKGROUND: Drug-induced depigmentation is frequently observed in humans undergoing tyrosine kinase inhibitor therapy, whereas it is not reported in dogs. The skin depigmentation can occur after the first week of treatment and it is reversible within a few weeks after drug discontinuation. OBJECTIVES: To report the clinical and histopathological features of an episode of cutaneous adverse drug reaction associated with short term administration of toceranib phosphate...
February 6, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28164402/allergen-specific-immunotherapy-prescription-patterns-in-veterinary-practice-a-us-population-based-cohort-study
#19
Kathy Chu Tater, William Elliott Cole, Paul David Pion
BACKGROUND: Poor adherence to continuing allergen-specific immunotherapy treatment (ASIT) may be an issue in veterinary medicine. No studies describe how allergen tests are used in general veterinary practice, including the percentage of patients that receive ASIT after allergen testing. HYPOTHESIS/OBJECTIVES: Assess veterinary ASIT patterns in United States general practices. ANIMALS: Dogs (n = 2,557) and 121 cats allergen-tested at 177 hospitals (173 general practice and four specialty practices) in 44 states...
February 5, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28164398/prevalence-of-house-dust-mites-in-the-homes-of-atopic-dogs-in-finland
#20
Kirsti J M Schildt, Riitta T K Seppänen, Anna K Hielm-Björkman, Leena E Saijonmaa-Koulumies, Svetlana Belova
BACKGROUND: The house dust mites (HDM) Dermatophagoides farinae and D. pteronyssinus are important environmental allergens implicated in the pathogenesis of human and canine atopic dermatitis. Sensitization to HDM measured by allergen-specific IgE is common in Finnish atopic dogs. Studies on HDM prevalence in Finland are few but suggest that HDM are scarce. OBJECTIVE: The aim of the present study was to evaluate the prevalence of HDM in the home environments of atopic dogs in Finland...
February 5, 2017: Veterinary Dermatology
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