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Veterinary Dermatology

Katrin Timm, Ralf S Mueller, Claudia S Nett-Mettler
BACKGROUND: Subcutaneous allergen immunotherapy (SCIT) is an established and efficacious therapy for canine atopic dermatitis (AD). In humans, intralymphatic immunotherapy (ILIT) was reported to be associated with fewer and less severe adverse effects than subcutaneous allergen immunotherapy and to be efficacious for several years after three intralymphatic injections. OBJECTIVE: To evaluate safety and effects of ILIT in a case series of dogs with (AD). ANIMALS: Fifty one privately owned dogs with AD...
January 12, 2018: Veterinary Dermatology
Matthew J H Carnett, Jon D Plant
BACKGROUND: Percutaneous testing (PT) is preferred to intradermal testing in humans for the in vivo identification of allergen hypersensitivity, but the methodology has not been well described for use in dogs with atopic dermatitis. HYPOTHESIS/OBJECTIVES: To identify the irritant threshold concentrations (ITC) of eight aeroallergens using a commercial prick test device in normal dogs. ANIMALS: Twenty healthy, privately owned dogs. METHODS: Percutaneous testing was performed using the GREER® Pick® System (Stallergenes Greer; Lenoir, NC, USA)...
January 8, 2018: Veterinary Dermatology
Alberto M Cordero, Simon Quek, Ralf S Mueller
BACKGROUND: Generalized demodicosis is a common disease in dogs and doramectin has been reported as a successful treatment. Different treatment protocols using doramectin have not been previously evaluated. OBJECTIVE: To evaluate whether oral administration of doramectin twice a week is more effective than administration by subcutaneous injection once a week. ANIMALS: Twenty nine privately owned dogs affected with generalized demodicosis. METHODS: Dogs randomly received one of two treatments...
December 29, 2017: Veterinary Dermatology
Ryota Asahina, Hidetaka Nishida, Hiroaki Kamishina, Sadatoshi Maeda
BACKGROUND: Interleukin (IL)-33 has been implicated in the pathogenesis of canine atopic dermatitis, a Type 2 T helper cell (Th2)-associated disease. In humans, IL-33 mediates its biological effects through the receptor suppression of tumourigenicity 2 (ST2), which is preferentially expressed on Th2 cells. The effects of IL-33 on canine Th2 cells are unclear. HYPOTHESIS/OBJECTIVES: ST2 may be preferentially expressed on canine Th2 cells; IL-33 may induce the transcription of Th2 cytokines from these cells...
November 26, 2017: Veterinary Dermatology
Julia So Severo, Aline Elisa Santana, Valeria Aoki, Nilceo S Michalany, Matheus Matioli Mantovani, Carlos Eduardo Larsson, Carlos Eduardo Larsson
BACKGROUND: C-reactive protein (CRP) is a major acute phase protein in dogs and may be an inflammatory marker of autoimmune diseases. HYPOTHESIS/OBJECTIVES: To measure pre- and post-treatment CRP levels in dogs with superficial pyoderma (SP) and pemphigus foliaceus (PF) compared to normal dogs; to evaluate possible correlation between CRP values, indirect immunofluorescence (IIF), and pemphigus foliaceus extent and severity index (PEFESI) scores. ANIMALS: Fifty nine dogs divided into three groups: Group I (control, n = 31), Group II (SP, n = 14) and Group III (PF, n = 14)...
November 22, 2017: Veterinary Dermatology
Lara M Tomich, Jason B Pieper, Adam W Stern
BACKGROUND: Dermoscopy is a noninvasive diagnostic technique that allows visualization of structures of the superficial dermis not visible with the naked eye. HYPOTHESIS/OBJECTIVES: To assess the usefulness and applicability of dermoscopy for evaluation of healthy equine skin. ANIMALS: Twelve healthy horses from a research herd. METHODS: Five regions (cheek, lateral neck, dorsum, flank and abdomen) were examined with contact dermoscopy using both nonpolarized and polarized light at both 17-fold and 24-fold magnification...
November 15, 2017: Veterinary Dermatology
Sara Legnani, Eric Zini, Paola Roccabianca, Beatrice Funiciello, Giordana Zanna
BACKGROUND: Dermoscopy is a diagnostic tool that has been introduced into small animal dermatology for the evaluation of hair and the skin surface. To the best of the authors' knowledge, the use of this technique on horses and the dermoscopic appearance of equine hair and skin have yet to be reported. HYPOTHESIS/OBJECTIVES: To assess the feasibility of dermoscopy, and to describe hair and skin surface features of healthy warmblood horses. ANIMALS: Thirty four client-owned, healthy adult horses...
November 1, 2017: Veterinary Dermatology
Mathilde Catarino, Daniel Combarros-Garcia, Philippe Mimouni, Charline Pressanti, Marie C Cadiergues
BACKGROUND: Nasal hyperkeratosis may cause discomfort in dogs by predisposing them to fissures and secondary bacterial infection. Approaches to treatment have been described anecdotally; the effectiveness of such therapies remains unproven. HYPOTHESIS/OBJECTIVES: To investigate the efficacy of a balm containing essential oils and essential fatty acids in dogs with idiopathic nasal hyperkeratosis. ANIMALS: Client-owned dogs with noncomplicated nasal hyperkeratosis...
October 27, 2017: Veterinary Dermatology
(no author information available yet)
No abstract text is available yet for this article.
February 2018: Veterinary Dermatology
Frane Banovic, Thierry Olivry, Wolfgang Bäumer, Judy Paps, Jessica Stahl, Ana Rogers, Megan Jacob
BACKGROUND: Diluted sodium hypochlorite represents an inexpensive and widely available topical antiseptic, but there are no tolerability and efficacy data in veterinary dermatology. OBJECTIVES: To determine the in vivo antibacterial effect and tolerability of topical diluted bleach application and to assess its in vitro effect on skin barrier lipids and anti-inflammatory properties on keratinocytes. METHODS: Topical hypochlorite at 0.05% and tap water were applied to both sides of the thorax of four healthy dogs...
February 2018: Veterinary Dermatology
Sandra N Koch, Sheila M F Torres, Sandra Diaz, Sophie Gilbert, Aaron Rendahl
BACKGROUND: Oral ciclosporin has been reported to be efficacious for feline inflammatory skin diseases; however, cats are often difficult to medicate orally. HYPOTHESIS/OBJECTIVE: To evaluate the efficacy and tolerability of subcutaneous ciclosporin administered to cats with allergic skin disease. ANIMALS: Eleven client-owned cats with nonseasonal clinical signs. METHODS: Prospective open label trial. Ciclosporin 50 mg/mL solution for injection (Sandimune®, Novartis; NJ, USA) was administered subcutaneously for 60 days with initial doses ranging from 2...
October 25, 2017: Veterinary Dermatology
Audrey Belmudes, Charline Pressanti, Paul Y Barthez, Eloy Castilla-Castaño, Lionel Fabries, Marie C Cadiergues
BACKGROUND: Computed tomography (CT) is considered to be the reference method to evaluate middle ear structures. OBJECTIVES: To evaluate the presence and severity of CT changes in the middle ear and establish if any specific clinical presentations are associated with otitis media. ANIMALS: Medical records of animals referred for CT with history and clinical signs consistent with middle ear disease. METHODS: Retrospective evaluation of CT examinations of tympanic bullae performed over a six year period...
October 10, 2017: Veterinary Dermatology
Frane Banovic, Carmen Jerry, Elizabeth Howerth
BACKGROUND: Dermal arteritis of the nasal philtrum is a rarely reported condition commonly affecting large breed dogs. OBJECTIVE: To describe the effective treatment of nasal philtrum arteritis with topical tacrolimus in one dog. ANIMAL: A 9-year-old, intact male German shorthair pointer dog was presented with well-demarcated deep erythematous ulcers targeting exclusively the skin of the nasal philtrum, accompanied by frequent series of haemorrhage...
October 8, 2017: Veterinary Dermatology
Alberto M Cordero, Galia Sheinberg-Waisburd, Camilo Romero Núñez, Rafael Heredia
No abstract text is available yet for this article.
October 8, 2017: Veterinary Dermatology
Catherine M Chan, Angela E Frimberger, Antony S Moore
BACKGROUND: Limited information is available regarding the treatment and outcome of dogs with epitheliotropic lymphoma. The disease typically has a poor prognosis. OBJECTIVES: To characterize the clinical signs, identify prognostic factors and evaluate the treatment outcome of dogs with epitheliotropic lymphoma. METHODS: A retrospective review of medical records from 2003 to 2015. Treatment details, tumour response and survival time were recorded for 148 dogs...
October 6, 2017: Veterinary Dermatology
Rosanna Marsella, Kim Ahrens, Rachel Sanford
BACKGROUND: IL-31 is a cytokine that is believed to play an important role in atopic dermatitis (AD). IL-31 levels positively correlate with disease severity in children with AD. Currently, there is no study that has investigated such a correlation in atopic dogs. HYPOTHESIS/OBJECTIVE: The purpose of this study was to evaluate the correlation between IL-31 serum levels and severity of dermatitis. It was hypothesized that a positive correlation exists between severity of AD and circulating levels of IL-31...
October 6, 2017: Veterinary Dermatology
Catherine A Outerbridge, Verena K Affolter, Leslie A Lyons, Samantha L Crothers, Andrea T H Lam, Terri E Bonenberger, Peter J Ihrke, Stephen D White
BACKGROUND: Between 2000 and 2012, nine cats were examined with a visually distinctive, progressive crusting dermatitis that was poorly responsive to all attempted therapies. OBJECTIVES: Documentation of clinical and histopathological findings of this disease. ANIMALS: Nine privately owned cats. METHODS: Retrospective study. RESULTS: Eight neutered males and one (presumably spayed) female ranging in age from two to eight years, presented for a progressive, well-demarcated, crusting dermatitis with variable pruritus of 1...
October 6, 2017: Veterinary Dermatology
Anja Ziegler, Eman Hamza, Sigridur Jonsdottir, Claudio Rhyner, Bettina Wagner, Gertraud Schüpbach, Vilhjalmur Svansson, Sigurbjorg Torsteinsdottir, Eliane Marti
BACKGROUND: Insect bite hypersensitivity (IBH) is an allergic dermatitis of horses caused by bites of Culicoides spp. IBH does not occur in Iceland because of the absence of Culicoides, but the prevalence is high in horses imported from Iceland to environments where Culicoides are present. HYPOTHESIS/OBJECTIVE: Test, in a longitudinal study before and after Culicoides exposure, whether a primary sensitizing Culicoides allergen can be identified and if an increase of allergen-specific immunoglobulin (Ig)E or IgG subclasses precedes clinical signs of IBH...
October 5, 2017: Veterinary Dermatology
Aiden Foster
No abstract text is available yet for this article.
October 2017: Veterinary Dermatology
Aurore F Laprais, Petra Bizikova, Erin W Lashnits, Alison Tucker, Keith E Linder
BACKGROUND: In humans, scleromyxoedema is a chronic progressive skin condition traditionally characterized by deposits of mucin, increased number of fibroblasts and fibrosis in the skin, and by systemic disease. Thyroid disease is typically absent. A monoclonal gammopathy is usually present, as are other comorbidities. Descriptions of scleromyxoedema in the veterinary literature are limited to a single feline case. One dog, previously reported as having papular mucinosis, exhibited features that matched the more current diagnostic criteria of scleromyxoedema...
October 2017: Veterinary Dermatology
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