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Veterinary Dermatology

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https://www.readbyqxmd.com/read/29143381/comparing-dermoscopy-and-histological-examination-of-normal-equine-skin
#1
Lara M Tomich, Jason B Pieper, Adam W Stern
BACKGROUND: Dermoscopy is a noninvasive diagnostic technique that allows visualization of structures of the superficial dermis not visible with the naked eye. HYPOTHESIS/OBJECTIVES: To assess the usefulness and applicability of dermoscopy for evaluation of healthy equine skin. ANIMALS: Twelve healthy horses from a research herd. METHODS: Five regions (cheek, lateral neck, dorsum, flank and abdomen) were examined with contact dermoscopy using both nonpolarized and polarized light at both 17-fold and 24-fold magnification...
November 15, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/29094427/dermoscopic-analysis-of-the-skin-of-healthy-warmblood-horses-a-descriptive-study-of-34-cases-in-italy
#2
Sara Legnani, Eric Zini, Paola Roccabianca, Beatrice Funiciello, Giordana Zanna
BACKGROUND: Dermoscopy is a diagnostic tool that has been introduced into small animal dermatology for the evaluation of hair and the skin surface. To the best of the authors' knowledge, the use of this technique on horses and the dermoscopic appearance of equine hair and skin have yet to be reported. HYPOTHESIS/OBJECTIVES: To assess the feasibility of dermoscopy, and to describe hair and skin surface features of healthy warmblood horses. ANIMALS: Thirty four client-owned, healthy adult horses...
November 1, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/29076573/control-of-canine-idiopathic-nasal-hyperkeratosis-with-a-natural-skin-restorative-balm-a-randomized-double-blind-placebo-controlled-study
#3
Mathilde Catarino, Daniel Combarros-Garcia, Philippe Mimouni, Charline Pressanti, Marie C Cadiergues
BACKGROUND: Nasal hyperkeratosis may cause discomfort in dogs by predisposing them to fissures and secondary bacterial infection. Approaches to treatment have been described anecdotally; the effectiveness of such therapies remains unproven. HYPOTHESIS/OBJECTIVES: To investigate the efficacy of a balm containing essential oils and essential fatty acids in dogs with idiopathic nasal hyperkeratosis. ANIMALS: Client-owned dogs with noncomplicated nasal hyperkeratosis...
October 27, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/29068099/subcutaneous-administration-of-ciclosporin-in-11-allergic-cats-a-pilot-open-label-uncontrolled-clinical-trial
#4
Sandra N Koch, Sheila M F Torres, Sandra Diaz, Sophie Gilbert, Aaron Rendahl
BACKGROUND: Oral ciclosporin has been reported to be efficacious for feline inflammatory skin diseases; however, cats are often difficult to medicate orally. HYPOTHESIS/OBJECTIVE: To evaluate the efficacy and tolerability of subcutaneous ciclosporin administered to cats with allergic skin disease. ANIMALS: Eleven client-owned cats with nonseasonal clinical signs. METHODS: Prospective open label trial. Ciclosporin 50 mg/mL solution for injection (Sandimune®, Novartis; NJ, USA) was administered subcutaneously for 60 days with initial doses ranging from 2...
October 25, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28994490/computed-tomographic-findings-in-205-dogs-with-clinical-signs-compatible-with-middle-ear-disease-a-retrospective-study
#5
Audrey Belmudes, Charline Pressanti, Paul Y Barthez, Eloy Castilla-Castaño, Lionel Fabries, Marie C Cadiergues
BACKGROUND: Computed tomography (CT) is considered to be the reference method to evaluate middle ear structures. OBJECTIVES: To evaluate the presence and severity of CT changes in the middle ear and establish if any specific clinical presentations are associated with otitis media. ANIMALS: Medical records of animals referred for CT with history and clinical signs consistent with middle ear disease. METHODS: Retrospective evaluation of CT examinations of tympanic bullae performed over a six year period...
October 10, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28990239/tacrolimus-therapy-for-dermal-arteritis-of-the-nasal-philtrum-refractory-to-surgery-and-anti-inflammatory-therapy-doxycycline-niacinamide-and-topical-fluocinolone-in-a-dog
#6
Frane Banovic, Carmen Jerry, Elizabeth Howerth
BACKGROUND: Dermal arteritis of the nasal philtrum is a rarely reported condition commonly affecting large breed dogs. OBJECTIVE: To describe the effective treatment of nasal philtrum arteritis with topical tacrolimus in one dog. ANIMAL: A 9-year-old, intact male German shorthair pointer dog was presented with well-demarcated deep erythematous ulcers targeting exclusively the skin of the nasal philtrum, accompanied by frequent series of haemorrhage...
October 8, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28990238/early-onset-canine-generalized-demodicosis
#7
LETTER
Alberto M Cordero, Galia Sheinberg-Waisburd, Camilo Romero Núñez, Rafael Heredia
No abstract text is available yet for this article.
October 8, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28983988/clinical-outcome-and-prognosis-of-dogs-with-histopathological-features-consistent-with-epitheliotropic-lymphoma-a-retrospective-study-of-148-cases-2003-2015-in-australia
#8
Catherine M Chan, Angela E Frimberger, Antony S Moore
BACKGROUND: Limited information is available regarding the treatment and outcome of dogs with epitheliotropic lymphoma. The disease typically has a poor prognosis. OBJECTIVES: To characterize the clinical signs, identify prognostic factors and evaluate the treatment outcome of dogs with epitheliotropic lymphoma. METHODS: A retrospective review of medical records from 2003 to 2015. Treatment details, tumour response and survival time were recorded for 148 dogs...
October 6, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28983982/investigation-of-the-correlation-of-serum-il-31-with-severity-of-dermatitis-in-an-experimental-model-of-canine-atopic-dermatitis-using-beagle-dogs
#9
Rosanna Marsella, Kim Ahrens, Rachel Sanford
BACKGROUND: IL-31 is a cytokine that is believed to play an important role in atopic dermatitis (AD). IL-31 levels positively correlate with disease severity in children with AD. Currently, there is no study that has investigated such a correlation in atopic dogs. HYPOTHESIS/OBJECTIVE: The purpose of this study was to evaluate the correlation between IL-31 serum levels and severity of dermatitis. It was hypothesized that a positive correlation exists between severity of AD and circulating levels of IL-31...
October 6, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28983976/an-unresponsive-progressive-pustular-and-crusting-dermatitis-with-acantholysis-in-nine-cats
#10
Catherine A Outerbridge, Verena K Affolter, Leslie A Lyons, Samantha L Crothers, Andrea T H Lam, Terri E Bonenberger, Peter J Ihrke, Stephen D White
BACKGROUND: Between 2000 and 2012, nine cats were examined with a visually distinctive, progressive crusting dermatitis that was poorly responsive to all attempted therapies. OBJECTIVES: Documentation of clinical and histopathological findings of this disease. ANIMALS: Nine privately owned cats. METHODS: Retrospective study. RESULTS: Eight neutered males and one (presumably spayed) female ranging in age from two to eight years, presented for a progressive, well-demarcated, crusting dermatitis with variable pruritus of 1...
October 6, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28980353/longitudinal-analysis-of-allergen-specific-ige-and-igg-subclasses-as-potential-predictors-of-insect-bite-hypersensitivity-following-first-exposure-to-culicoides-in-icelandic-horses
#11
Anja Ziegler, Eman Hamza, Sigridur Jonsdottir, Claudio Rhyner, Bettina Wagner, Gertraud Schüpbach, Vilhjalmur Svansson, Sigurbjorg Torsteinsdottir, Eliane Marti
BACKGROUND: Insect bite hypersensitivity (IBH) is an allergic dermatitis of horses caused by bites of Culicoides spp. IBH does not occur in Iceland because of the absence of Culicoides, but the prevalence is high in horses imported from Iceland to environments where Culicoides are present. HYPOTHESIS/OBJECTIVE: Test, in a longitudinal study before and after Culicoides exposure, whether a primary sensitizing Culicoides allergen can be identified and if an increase of allergen-specific immunoglobulin (Ig)E or IgG subclasses precedes clinical signs of IBH...
October 5, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28952176/pilot-evaluation-of-the-antipruritic-efficacy-of-a-topical-transient-receptor-potential-melastatin-subfamily-8-trpm8-agonist-in-dogs-with-atopic-dermatitis-and-pedal-pruritus
#12
Chie Tamamoto-Mochizuki, K Marcia Murphy, Thierry Olivry
BACKGROUND: Atopic dermatitis (AD) requires a multimodal therapy and there is a need for effective adjunctive interventions. TRPM8 agonists are known to alleviate pruritus by inducing cooling. OBJECTIVES: To evaluate the efficacy of a novel TRPM8 agonist, 1-diisopropylphosphorylheptane (Cryosim-1), in atopic dogs. ANIMALS: Nine client owned dogs with moderate to severe pedal pruritus associated with nonseasonal AD. METHODS: This was a prospective, randomized, double-blinded, intraindividual, placebo-controlled study...
September 26, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28921723/effect-of-prophylactic-cefalexin-treatment-on-the-development-of-bacterial-infection-in-acute-radiation-induced-dermatitis-in-dogs-a-blinded-randomized-controlled-prospective-clinical-trial
#13
Michele A Keyerleber, Lluís Ferrer
BACKGROUND: Acute radiation-induced dermatitis (ARID) is a common sequela of radiation therapy and carries the risk of secondary bacterial skin infection. No standard of care exists for managing canine ARID and evidence-based guidelines are lacking; however, prophylactic use of antibiotics is common. HYPOTHESIS/OBJECTIVES: To evaluate the impact of prophylactic cefalexin on the prevalence and severity of bacterial infection in canine ARID. ANIMALS: Seventeen dogs treated with definitive-intent radiotherapy...
September 18, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28921687/multimodal-treatment-of-a-dog-with-disseminated-cutaneous-viral-papillomatosis
#14
Britt J Levy, Susannah J Sample, Hang Yuan
BACKGROUND: Canine papillomaviruses (CPVs) are associated with varied cutaneous manifestations. Spontaneous resolution typically occurs within one to 12 months. This case report describes multimodal treatment of a dog with severe disseminated papillomatosis. CLINICAL SUMMARY: An eight-month-old, female spayed, mixed breed dog was presented with a two month history of rapidly progressing papillomatosis and lack of response to oral azithromycin therapy. The dog was severely pruritic and malodorous; the weight and growth of lesions had progressed to affect the dog's gait and vision, and led to decreased quality of life...
September 18, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28913896/a-novel-non-azole-topical-treatment-reduces-malassezia-numbers-and-associated-dermatitis-a-short-term-prospective-randomized-blinded-and-placebocontrolled-trial-in-naturally-infected-dogs
#15
Ylva Sjöström, Paul Mellor, Kerstin Bergvall
BACKGROUND: Malassezia yeast overgrowth on the skin is a common and often recurrent cause of dermatitis in dogs; it can be an exacerbating factor of atopic dermatitis. Anti-fungal drugs have been a standard treatment, but there is some concern that resistance may be evolving in a spectrum of Malassezia species. Safe, efficient and easy-to-use alternatives are needed. OBJECTIVES: To assess if a commercially available topical non-azole solution applied to paws affected by Malassezia-associated dermatitis (MAD), could ameliorate Malassezia numbers and associated signs over a short term (14 day) trial...
September 14, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28906043/diluted-sodium-hypochlorite-bleach-in-dogs-antiseptic-efficacy-local-tolerability-and-in-vitro-effect-on-skin-barrier-function-and-inflammation
#16
Frane Banovic, Thierry Olivry, Wolfgang Bäumer, Judy Paps, Jessica Stahl, Ana Rogers, Megan Jacob
BACKGROUND: Diluted sodium hypochlorite represents an inexpensive and widely available topical antiseptic, but there are no tolerability and efficacy data in veterinary dermatology. OBJECTIVES: To determine the in vivo antibacterial effect and tolerability of topical diluted bleach application and to assess its in vitro effect on skin barrier lipids and anti-inflammatory properties on keratinocytes. METHODS: Topical hypochlorite at 0.05% and tap water were applied to both sides of the thorax of four healthy dogs...
September 14, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28906040/a-blinded-randomized-clinical-trial-evaluating-the-efficacy-and-safety-of-lokivetmab-compared-to-ciclosporin-in-client-owned-dogs-with-atopic-dermatitis
#17
Hilde Moyaert, Leen Van Brussel, Stasia Borowski, Monica Escalada, Sean P Mahabir, Rodney R Walters, Michael R Stegemann
BACKGROUND: Lokivetmab is an injectable anti-canine-IL-31 monoclonal antibody to treat clinical manifestations of atopic dermatitis (AD) in dogs. HYPOTHESIS/OBJECTIVES: To characterize the efficacy and safety of lokivetmab, and to demonstrate its noninferiority to ciclosporin under field conditions. ANIMALS: Dogs with chronic AD (n = 274) were enrolled from 40 practices in Belgium, The Netherlands, France and Germany. METHODS: Animals were randomized (1:1) to oral ciclosporin (5 mg/kg/once daily) or monthly injectable lokivetmab (1-3...
September 14, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28901591/evaluation-of-the-correlation-between-scoring-feline-allergic-dermatitis-and-feline-extent-and-severity-index-and-skin-hydration-in-atopic-cats
#18
Marcin P Szczepanik, Piotr M Wilkołek, Łukasz R Adamek, Marcin Zając, Marcin Gołyński, Wiesław Sitkowski, Iwona Taszkun
BACKGROUND: Evaluation of the severity of clinical signs of cats with allergic skin diseases has used two scoring systems: Scoring Feline Allergic Dermatitis (SCORFAD) and the Feline Extent and Severity Index (FeDESI). The integrity of the cutaneous barrier can also be evaluated by measuring skin hydration. A correlation between the clinical score and skin hydration has been observed in humans and dogs with atopic dermatitis (AD). HYPOTHESIS: To demonstrate a correlation between the clinical score and skin hydration of cats affected with presumed AD...
September 13, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28868812/application-of-three-hygrometers-under-different-skin-conditions-in-dogs-dry-moist-and-haired-skin
#19
Yutaka Momota, Kenichiro Shimada, Naoyuki Minorikawa, Azusa Gin, Takako Matsubara, Yuka Nakamura, Masaaki Katayama, Toshinori Sako
BACKGROUND: Hydration is one parameter of skin barrier function. The Skicon-200EX(®) and Corneometer CM825(®) are hygrometers used to measure skin hydration in humans based on different measurement methods. The ASA-MX3(®) is a hygrometer used to obtain measurements at haired skin sites in humans. HYPOTHESIS/OBJECTIVES: To validate three hygrometers to measure skin dryness in dogs. ANIMALS: Six clinically normal research dogs. METHODS: In vivo evaluation of three hygrometers for three different skin types was performed...
September 3, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28868794/canine-demodicosis-a-retrospective-study-of-a-veterinary-hospital-population-in-california-usa-2000-2016
#20
Daniel G Bowden, Catherine A Outerbridge, Marguerite B Kissel, Jerome N Baron, Stephen D White
BACKGROUND: Demodex spp. are cutaneous mites that cause clinical disease when present in increased numbers. There is an association in some dogs with underlying systemic disease or immunosuppressive medications. HYPOTHESIS/OBJECTIVES: Retrospective study to document breed predisposition, identify any concurrent diseases or underlying immunosuppressive conditions, and to determine the frequency of demodicosis recurrence after treatment completion. ANIMALS: There were 431 dogs with demodicosis presented to a veterinary teaching hospital in California, USA, from 2000 to 2016...
September 3, 2017: Veterinary Dermatology
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