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Veterinary Dermatology

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https://www.readbyqxmd.com/read/28921723/effect-of-prophylactic-cefalexin-treatment-on-the-development-of-bacterial-infection-in-acute-radiation-induced-dermatitis-in-dogs-a-blinded-randomized-controlled-prospective-clinical-trial
#1
Michele A Keyerleber, Lluís Ferrer
BACKGROUND: Acute radiation-induced dermatitis (ARID) is a common sequela of radiation therapy and carries the risk of secondary bacterial skin infection. No standard of care exists for managing canine ARID and evidence-based guidelines are lacking; however, prophylactic use of antibiotics is common. HYPOTHESIS/OBJECTIVES: To evaluate the impact of prophylactic cefalexin on the prevalence and severity of bacterial infection in canine ARID. ANIMALS: Seventeen dogs treated with definitive-intent radiotherapy...
September 18, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28921687/multimodal-treatment-of-a-dog-with-disseminated-cutaneous-viral-papillomatosis
#2
Britt J Levy, Susannah J Sample, Hang Yuan
BACKGROUND: Canine papillomaviruses (CPVs) are associated with varied cutaneous manifestations. Spontaneous resolution typically occurs within one to 12 months. This case report describes multimodal treatment of a dog with severe disseminated papillomatosis. CLINICAL SUMMARY: An eight-month-old, female spayed, mixed breed dog was presented with a two month history of rapidly progressing papillomatosis and lack of response to oral azithromycin therapy. The dog was severely pruritic and malodorous; the weight and growth of lesions had progressed to affect the dog's gait and vision, and led to decreased quality of life...
September 18, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28913945/abstracts
#3
(no author information available yet)
No abstract text is available yet for this article.
September 14, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28913896/a-novel-non-azole-topical-treatment-reduces-malassezia-numbers-and-associated-dermatitis-a-short-term-prospective-randomized-blinded-and-placebocontrolled-trial-in-naturally-infected-dogs
#4
Ylva Sjöström, Paul Mellor, Kerstin Bergvall
BACKGROUND: Malassezia yeast overgrowth on the skin is a common and often recurrent cause of dermatitis in dogs; it can be an exacerbating factor of atopic dermatitis. Anti-fungal drugs have been a standard treatment, but there is some concern that resistance may be evolving in a spectrum of Malassezia species. Safe, efficient and easy-to-use alternatives are needed. OBJECTIVES: To assess if a commercially available topical non-azole solution applied to paws affected by Malassezia-associated dermatitis (MAD), could ameliorate Malassezia numbers and associated signs over a short term (14 day) trial...
September 14, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28906043/diluted-sodium-hypochlorite-bleach-in-dogs-antiseptic-efficacy-local-tolerability-and-in-vitro-effect-on-skin-barrier-function-and-inflammation
#5
Frane Banovic, Thierry Olivry, Wolfgang Bäumer, Judy Paps, Jessica Stahl, Ana Rogers, Megan Jacob
BACKGROUND: Diluted sodium hypochlorite represents an inexpensive and widely available topical antiseptic, but there are no tolerability and efficacy data in veterinary dermatology. OBJECTIVES: To determine the in vivo antibacterial effect and tolerability of topical diluted bleach application and to assess its in vitro effect on skin barrier lipids and anti-inflammatory properties on keratinocytes. METHODS: Topical hypochlorite at 0.05% and tap water were applied to both sides of the thorax of four healthy dogs...
September 14, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28906040/a-blinded-randomized-clinical-trial-evaluating-the-efficacy-and-safety-of-lokivetmab-compared-to-ciclosporin-in-client-owned-dogs-with-atopic-dermatitis
#6
Hilde Moyaert, Leen Van Brussel, Stasia Borowski, Monica Escalada, Sean P Mahabir, Rodney R Walters, Michael R Stegemann
BACKGROUND: Lokivetmab is an injectable anti-canine-IL-31 monoclonal antibody to treat clinical manifestations of atopic dermatitis (AD) in dogs. HYPOTHESIS/OBJECTIVES: To characterize the efficacy and safety of lokivetmab, and to demonstrate its noninferiority to ciclosporin under field conditions. ANIMALS: Dogs with chronic AD (n = 274) were enrolled from 40 practices in Belgium, The Netherlands, France and Germany. METHODS: Animals were randomized (1:1) to oral ciclosporin (5 mg/kg/once daily) or monthly injectable lokivetmab (1-3...
September 14, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28901591/evaluation-of-the-correlation-between-scoring-feline-allergic-dermatitis-and-feline-extent-and-severity-index-and-skin-hydration-in-atopic-cats
#7
Marcin P Szczepanik, Piotr M Wilkołek, Łukasz R Adamek, Marcin Zając, Marcin Gołyński, Wiesław Sitkowski, Iwona Taszkun
BACKGROUND: Evaluation of the severity of clinical signs of cats with allergic skin diseases has used two scoring systems: Scoring Feline Allergic Dermatitis (SCORFAD) and the Feline Extent and Severity Index (FeDESI). The integrity of the cutaneous barrier can also be evaluated by measuring skin hydration. A correlation between the clinical score and skin hydration has been observed in humans and dogs with atopic dermatitis (AD). HYPOTHESIS: To demonstrate a correlation between the clinical score and skin hydration of cats affected with presumed AD...
September 13, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28868812/application-of-three-hygrometers-under-different-skin-conditions-in-dogs-dry-moist-and-haired-skin
#8
Yutaka Momota, Kenichiro Shimada, Naoyuki Minorikawa, Azusa Gin, Takako Matsubara, Yuka Nakamura, Masaaki Katayama, Toshinori Sako
BACKGROUND: Hydration is one parameter of skin barrier function. The Skicon-200EX(®) and Corneometer CM825(®) are hygrometers used to measure skin hydration in humans based on different measurement methods. The ASA-MX3(®) is a hygrometer used to obtain measurements at haired skin sites in humans. HYPOTHESIS/OBJECTIVES: To validate three hygrometers to measure skin dryness in dogs. ANIMALS: Six clinically normal research dogs. METHODS: In vivo evaluation of three hygrometers for three different skin types was performed...
September 3, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28868794/canine-demodicosis-a-retrospective-study-of-a-veterinary-hospital-population-in-california-usa-2000-2016
#9
Daniel G Bowden, Catherine A Outerbridge, Marguerite B Kissel, Jerome N Baron, Stephen D White
BACKGROUND: Demodex spp. are cutaneous mites that cause clinical disease when present in increased numbers. There is an association in some dogs with underlying systemic disease or immunosuppressive medications. HYPOTHESIS/OBJECTIVES: Retrospective study to document breed predisposition, identify any concurrent diseases or underlying immunosuppressive conditions, and to determine the frequency of demodicosis recurrence after treatment completion. ANIMALS: There were 431 dogs with demodicosis presented to a veterinary teaching hospital in California, USA, from 2000 to 2016...
September 3, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28833761/generalized-papillomatosis-in-three-horses-associated-with-a-novel-equine-papillomavirus-ecpv8
#10
Keith E Linder, Petra Bizikova, Jennifer Luff, Dan Zhou, Hang Yuan, Babetta Breuhaus, Elizabeth Nelson, Robert Mackay
BACKGROUND: Currently, seven equine papillomaviruses (PV) are known and are associated with one of three different and distinct clinical presentations. HYPOTHESIS/OBJECTIVES: To report the clinical, histopathological and immunohistochemical findings in horses with generalized papillomatosis associated with a novel equine PV, Equus caballus papillomavirus 8 (EcPV8). ANIMALS: Three client-owned quarter horses. METHODS: Case report, retrospective...
August 22, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28833656/the-in-vitro-antibacterial-activity-of-incomplete-iron-salt-of-polyacrylic-acid-against-pseudomonas-aeruginosa-meticillin-resistant-staphylococcus-pseudintermedius-and-meticillin-resistant-s-aureus
#11
Meghan K Solc, J Scott Weese, Edward Jazic
BACKGROUND: The incomplete iron salt of polyacrylic acid (IIS-PAA) has been used for its haemostatic, wound healing and antibacterial properties in human patients. IIS-PAA is a water-soluble, acidic, hydrophilic polymer that is active at pH 2.9-4.0. HYPOTHESES/OBJECTIVES: To evaluate the antibacterial effect of IIS-PAA against Pseudomonas aeruginosa, meticillin-resistant Staphylococcus pseudintermedius (MRSP) and meticillin-resistant S. aureus (MRSA). METHODS: This was a prospective, nonblinded in vitro study...
August 22, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28833821/investigation-of-subclinical-bacteriuria-in-cats-with-dermatological-disease-receiving-long-term-glucocorticoids-and-or-ciclosporin
#12
Samantha L Lockwood, Anthea E Schick, Thomas P Lewis, Heide Newton
BACKGROUND: Dogs receiving long-term glucocorticoids or ciclosporin have an increased frequency of bacteriuria. No studies have investigated the frequency of bacteriuria in cats receiving long-term glucocorticoids and/or ciclosporin. HYPOTHESES/OBJECTIVES: To document whether subclinical bacteriuria occurs in cats receiving long-term glucocorticoid and/or ciclosporin for management of chronic disease. ANIMALS: Thirty two cats treated with parenteral glucocorticoids and/or oral glucocorticoids and/or ciclosporin were included...
August 18, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28833730/use-of-a-commercial-qpcr-assay-in-52-high-risk-shelter-cats-for-disease-identification-of-dermatophytosis-and-mycological-cure
#13
Karen A Moriello, Christian M Leutenegger
BACKGROUND: qPCR is used to test for dermatophytosis. OBJECTIVES: To determine the clinical usefulness of a commercial qPCR for confirming dermatophytosis in lesional cats, and the clinical usefulness of the qPCR Microsporum spp. and/or M. canis assay for confirming mycological cure. ANIMALS: Fifty two shelter cats with skin lesions. METHODS: qPCR testing of toothbrush fungal culture samples of lesions. RESULTS: qPCR and fungal culture (FC) matched in 49 of 52 cats...
August 18, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28815758/detection-of-cyprinid-herpesvirus-1-dna-in-cutaneous-squamous-cell-carcinoma-of-koi-carp-cyprinus-carpio
#14
Rubina Sirri, Sara Ciulli, Tim Barbé, Enrico Volpe, Maurizio Lazzari, Valeria Franceschini, Francesca Errani, Giuseppe Sarli, Luciana Mandrioli
BACKGROUND: Cutaneous squamous cell carcinoma (cSCC) is an uncommon disease affecting koi carp (Cyprinus carpio). Cutaneous papilloma (carp pox) is a benign epidermal proliferation reported in koi and has been shown to be caused by Cyprinid Herpesvirus 1 (CyHV1). HYPOTHESIS/OBJECTIVES: Histological, ultrastructural and molecular investigations were carried out aiming to investigate the aetiology of cSCC within archived tissue samples. ANIMALS: Surgical samples of masses located on the integument, fins and lips of 13 koi carp belonging to different private owners were included in this retrospective study...
August 16, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28776792/a-pilot-study-of-the-effect-of-pullulan-conjugated-der-f-2-allergen-specific-immunotherapy-on-canine-atopic-dermatitis
#15
Kouji Kawano, Takuya Mizuno
BACKGROUND: Dermatophagoides farinae is a major and common environmental house dust mite involved in canine atopic dermatitis (CAD). A formulation of recombinant protein Der f 2 is available in Japan for immunotherapy in dogs. HYPOTHESIS/OBJECTIVES: To evaluate the efficacy of a recombinant allergen based on Der f 2-pullulan for the treatment of cAD. METHODS: Dogs (n = 15) with atopic dermatitis were administered Der f 2 conjugated with pullulan (-P)...
August 4, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28776781/antimicrobial-treatment-of-necrotizing-fasciitis-and-septic-polyarthritis-in-a-cat-associated-with-streptococcus-canis-infection
#16
LETTER
Renata S Costa, Fabíola B Costa, Rosana R Barros
No abstract text is available yet for this article.
August 4, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28770578/detection-of-ige-reactive-proteins-in-hydrolysed-dog-foods
#17
Olivier Roitel, Lionel Bonnard, Alexandre Stella, Odile Schiltz, Delphine Maurice, Gaël Douchin, Sandrine Jacquenet, Claude Favrot, Bernard E Bihain, Nicolas Couturier
BACKGROUND: Commercial hydrolysed diets are used for the diagnosis of food allergy in dogs. The cleaved parent proteins are presumed to be too small to elicit an allergic response by reacting with allergen-specific immunoglobin E (IgE). OBJECTIVES: To evaluate three commercial hydrolysed dog diets for proteins. ANIMALS: Sera were collected from dogs with suspected food allergy. METHODS: Two batches of each hydrolysed diet were examined by electrophoresis and visualized by Coomassie blue, silver nitrate staining and IgE immunoblotting...
August 2, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28748560/results-of-allergen-specific-immunotherapy-in-atopic-dogs-with-malassezia-hypersensitivity-a-retrospective-study-of-16-cases
#18
Liselotte Åberg, Katarina Varjonen, Susanne Åhman
BACKGROUND: Hypersensitivity reactions to Malassezia spp have been shown to occur in dogs with atopic dermatitis (AD) and to cause exacerbation of clinical signs. Improvement of clinical signs following use of antifungal medication is seen with both Malassezia overgrowth or Malassezia hypersensitivity (MHS). Subcutaneous immunotherapy (SCIT) is considered a safe and effective treatment for management of canine AD. Adverse effects are considered rare. OBJECTIVES: To report on the use of SCIT with Malassezia extracts in mono-sensitized dogs...
July 26, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28748533/macrococcus-canis-and-m-caseolyticus-in-dogs-occurrence-genetic-diversity-and-antibiotic-resistance
#19
Kerstin Cotting, Christian Strauss, Sabrina Rodriguez-Campos, Ana Rostaher, Nina M Fischer, Petra J Roosje, Claude Favrot, Vincent Perreten
BACKGROUND: The discovery of a new Macrococcus canis species isolated from skin and infection sites of dogs led us to question if Macrococcus spp. are common in dogs and are resistant to antibiotics. HYPOTHESIS/OBJECTIVES: To evaluate the occurrence of Macrococcus spp. in dogs, determine antibiotic resistance profiles and genetic relationships. ANIMALS: One hundred and sixty two dogs (mainly West Highland white terriers and Newfoundland dogs) were screened for the presence of Macrococcus, including six dogs with Macrococcus infections...
July 26, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28736984/randomized-double-blinded-placebo-controlled-pilot-study-on-the-effects-of-topical-blackcurrant-emulsion-enriched-in-essential-fatty-acids-ceramides-and-18-beta-glycyrrhetinic-acid-on-clinical-signs-and-skin-barrier-function-in-dogs-with-atopic-dermatitis
#20
Rosanna Marsella, Luisa Cornegliani, Ibrahim Ozmen, Mary Bohannon, Kim Ahrens, Domenico Santoro
BACKGROUND: Lipid-based emulsions can be useful for the management of canine atopic dermatitis (cAD). 18-beta glycyrrhetinic acid (GRA), a component of liquorice root, has anti-inflammatory and anti-pruritic effects. HYPOTHESIS/OBJECTIVES: To evaluate the effects of a topical lipid emulsion containing ceramides, fatty acids and GRA on clinical signs of cAD and skin barrier in a randomized, double-blinded, placebo-controlled trial. METHODS: Client owned (n = 45) dogs with nonseasonal, mild/moderate AD, received either treatment or placebo for three months...
July 23, 2017: Veterinary Dermatology
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