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Journal de Mycologie Médicale

S Otašević, S Momčilović, M Petrović, O Radulović, N M Stojanović, V Arsić-Arsenijević
OBJECTIVE: The aim of this study was to evaluate the effectiveness of an alternative treatment in a form of recommended diet modification during and after conventional treatment with antifungals in patients with a chronic form of intestinal Candida overgrowth (ICOG). METHODS: The study included patients with ICOG divided in two subgroups: patients treated with nystatin and recommended diet regime (study group-SG) and the patients treated only with nystatin (control group-CG)...
August 27, 2018: Journal de Mycologie Médicale
A Farzanegan, M Roudbary, M Falahati, M Khoobi, E Gholibegloo, S Farahyar, P Karimi, M Khanmohammadi
OBJECTIVE: Candidiasis is one of the most opportunistic fungal infections in immunocompromised patients. The emergence of multidrug-resistant Candida species necessitates the development of novel antifungal agents. Seeking to the discovery of natural antifungal agents, this study aimed to synthesize a novel formulated nanocomposite containing Indolicidin (IN), antimicrobial peptide, and Graphene oxide (GO), kind of nanomaterial, against Candida growth using in vitro and in vivo experiments for the first time...
August 17, 2018: Journal de Mycologie Médicale
M Romero-Navarrete, L F Ruíz, A Castillo, R Arenas, M E Vega-Memije, J Xicohtencatl-Cortes, M Espinoza-Rivera, R Hernández-Castro
Chromoblastomycosis is defined as a chronic cutaneous and subcutaneous fungal infection caused by melanized or brown-pigmented fungi. A 63-year-old man farmer showed on external and internal part of the right arm, a well-delimited verrucous and hyperkeratotic plaque, with atrophic and cicatricial areas. Direct examination of skin scrapings samples showed the presence of muriform cells, a classic feature of chromoblastomycosis. Fungal isolation was performed in Sabouraud dextrose agar, and dark olivaceous colonies were isolated...
August 17, 2018: Journal de Mycologie Médicale
A Ben Youssef, A Kallel, Z Azaiz, S Jemel, N Bada, A Chouchen, N Belhadj-Salah, N Fakhfakh, S Belhadj, K Kallel
Onychomycosis is a fungal infection of nails caused by dermatophytes, yeasts or non-dermatophyte molds. The aim of our study was to describe the epidemiological features of onychomycoses encountered in the Tunis region. A retrospective study concerned 3458 cases of onychomycosis, confirmed by direct examination and/or a positive culture, was conducted in Parasitology - Mycology Laboratory, Rabta hospital, over a five-year period (2012-2016). Our patients were aged 1 to 85; more than half of the patients were aged over 60 years with a female predominance (67%)...
August 11, 2018: Journal de Mycologie Médicale
R Ribeiro de Carvalho, N Chaves Silva, M Cusinato, K S Tranches Dias, M H Dos Santos, C Viegas Junior, É Gonçalves Silva, A L Tranches Dias
Natural products with diverse bioactivities and structures are an important source of novel chemicals with pharmaceutical potentials. Combinations of bioactive compounds with classical antimicrobial agents against drug-resistant or low-susceptible Candida spp. have been studied. Guttiferone-A and its derivatives were combined with fluconazole through the checkerboard method and tested against Candida spp. The results obtained, especially the Fractional Inhibitory Concentration Index (FICI) determined to the combinations, suggests promising results on the treatment of Candida infections, principally for species that present resistance or low antifungal susceptibility...
August 10, 2018: Journal de Mycologie Médicale
M Khatami, N Zafarnia, M Heydarpoor Bami, I Sharifi, H Singh
With increase in isolation of multi and extensive drug resistance hospital pathogens (MDR, XDR) in burn centers of many hospitals in the world, attempt to use nanomaterials for treatment of burn-infected patients is the focus of researches all around the world. In the present investigation silver nanospheres (Ag NSs) has been synthesized by chicory seed exudates (CSE). The various parameters influencing the mechanism of Ag NSs synthesis including temperature, concentration, pH and time were studied. Greener Ag NSs were formed when the reaction conditions were altered with respect to pH, concentration of AgNO3 and incubation temperature...
August 9, 2018: Journal de Mycologie Médicale
S-Y-A-S-A Fattah, F Hariri, R Ngui, S-I-S Husman
Mucormycosis is a rare fungal infection and high mortality that commonly affects patients with the weakened immune system. We present an unusual case of tongue necrosis probably due to the healthcare-associated mucormycosis (HCM) in a diabetic patient. Although cannot be proved with certainty, we surmise that intubation as a risk factor in our case. The diagnosis was confirmed by histopathological examination (HPE) of the necrotic tissue specimen. The patient was responded well to lipid complex amphotericin B (250mg) regime after surgery...
September 2018: Journal de Mycologie Médicale
C Imbert, C Hennequin, A Coste
No abstract text is available yet for this article.
September 2018: Journal de Mycologie Médicale
S T Pote, U Khan, K K Lahiri, M S Patole, M R Thakar, S R Shah
Onychomycosis is the most common infection of the toe-nails or finger-nails and it may be caused by a large variety of fungal species. Achaetomium species which belong to the phylum Ascomycota (Family Chaetomiaceae), are usually soil saprophytes or endophytic fungi which have been rarely reported as human or animal pathogens. Here, we report a case of onychomycosis caused by Achaetomium strumarium in a healthy person who showed involvement of all fingers of both hands with yellowish brown discoloration. The causative agent isolated was identified as Achaetomium species by morphology, colony morphometry and growth at high temperature and as A...
September 2018: Journal de Mycologie Médicale
Khadija Bouksir, Mohamed Kazzaz, Hanie Fassi Fehri, Hassan Bouziane, Hajar Bouksir, Fatima El Haskouri
We report a case of onychomycosis caused by Monascus ruber from 57-year old women. The diagnosis was based on culture morphological characteristics on Sabouraud's Dextrose agar one with antibacterial (chloramphenicol) and the other with cycloheximide. The identification of specie was confirmed by DNA sequencing.
September 2018: Journal de Mycologie Médicale
N W Sit, Y S Chan, S C Lai, L N Lim, G T Looi, P L Tay, Y T Tee, Y Y Woon, K S Khoo, H C Ong
OBJECTIVES: This study was conducted to evaluate the antidermatophytic activity of 48 extracts obtained from medicinal plants (Cibotium barometz, Melastoma malabathricum, Meuhlenbeckia platyclada, Rhapis excelsa, Syzygium myrtifolium, Vernonia amygdalina) and marine algae (Caulerpa sertularioides, Kappaphycus alvarezii) against Trichophyton rubrum and Trichophyton interdigitale (ATCC reference strains), and the cytotoxicity using African monkey kidney epithelial (Vero) cells. Active plant extracts were screened for the presence of phytochemicals and tested against clinical isolates of Trichophyton tonsurans...
September 2018: Journal de Mycologie Médicale
S Smaoui, K Ennouri, A Chakchouk-Mtibaa, I Sellem, K Bouchaala, I Karray-Rebai, L Mellouli
A Streptomyces sp. strain TN71 was isolated from Tunisian Saharan soil and selected for its antimicrobial activity against phytopathogenic fungi. In an attempt to increase its anti-Fusarium oxysporum activity, GYM+S (glucose, yeast extract, malt extract and starch) culture medium was selected out of five different production media. Plackett-Burman design (PBD) was used to select yeast extract, malt extract and calcium carbonate (CaCO3 ) as parameters having significant effects on antifungal activity, and a Box-Behnken design was applied for further optimization...
September 2018: Journal de Mycologie Médicale
S Das, G Rai, R A Tigga, S Srivastava, P K Singh, R Sharma, S Datt, N P Singh, S A Dar
Candida auris has emerged as the multi-drug resistant non-albican candida species in critically ill patients admitted to intensive care units (ICU) causing bloodstream and other infections. It has often been misidentified as Candida famata, Candida sake, Rhodotorula glutinis, or Saccharomyces cerevisiae and Candida haemulonii by automated identification systems. We, in this study, discuss three patients who acquired Candida auris infection after 15 to 20days of their stay in medical ICU. Medical equipment, use of multiple antibiotics, and poor hand hygiene are the most probable predisposing factors attributing to its colonization at multiple anatomical sites leading to bloodstream infection...
September 2018: Journal de Mycologie Médicale
H F Z Touil, Z Boucherit-Otmani, K Boucherit
BACKGROUND: Invasive fungal infections are an emerging health problem worldwide. They are responsible for a significant rate of morbidity and mortality. Infections caused by Candida albicans involve proliferation of biofilms on biotic or abiotic surface. These adherent communities exhibit characteristics distinct from planktonic cells such as the ability to tolerate high concentrations of antifungal. OBJECTIVE: The object of our study was focused on the determination of the susceptibility to amphotericin B, caspofungin, voriconazole and two antifungal combinations (amphotericin B/caspofungin and amphotericin B/voriconazole) of both planktonic and sessile cells of C...
September 2018: Journal de Mycologie Médicale
A L Bidaud, A Chowdhary, E Dannaoui
Candida auris is an emerging fungal pathogen responsible for nosocomial invasive infection outbreaks on five continents. Large healthcare-related outbreaks of C. auris infection and colonization have been reported from different countries. Whole genome sequence analysis identified strong phylogeographic C. auris clades specific to particular geographical areas suggesting transmission of particular clades within countries. However, the mode of transmission within the healthcare environment is not clear and is likely to be multifactorial...
September 2018: Journal de Mycologie Médicale
G Hazirolan, N Koçak, A Karagöz
INTRODUCTION: Trichosporon asahii is the most common species that causes trichosporonosis. MATERIALS AND METHODS: In the present study, a collection of 68T. asahii strains recovered from hospitalized patients urine samples between 2011 and 2016 was examined. T. asahii strains were identified by sequencing the intergenic spacer 1 region (IGS1) and genotyped. In addition, proteinase, phospholipase, esterase, haemolytic activity, and biofilm formation of a total of T...
September 2018: Journal de Mycologie Médicale
S K Deshmukh, S A Verekar, Y G Chavan
Forty soil samples were collected from seven sites in the vicinity of Sambhar lake Rajasthan, India and screened for the presence of keratinophilic fungi using hair baiting techniques for isolation. Seventeen isolates were recovered and identified. The cultures were identified by recognition of their macro- and micro- morphological features. Their identification was confirmed by BLAST using ITS1-5.8S-ITS2 rDNA region and sequences have been deposited in NCBI data base. A total of 34 species belonging to 29 genera were isolated...
September 2018: Journal de Mycologie Médicale
S Akroum
OBJECTIVE OF THE STUDY: Candidiasis and dermatophytoses are benign infections in humans and animals, but they are very dreaded diseases in immunocompromised individuals. These infections become resistant to different treatments which make them more dangerous. In this work, we tried to find a new way for treating them. So we were interested in the antifungal activity of Camellia sinensis (tea); this plant is known to have many health benefits. MATERIALS AND METHODS: We tested the ability of the acetone and aqueous crude extracts of the plant to inhibit in vitro the growth of Candida albicans, Candida glabrata, Candida tropicalis, Candida krusei and Microsporum persicolor...
September 2018: Journal de Mycologie Médicale
L García-Agudo, M Rodríguez-Iglesias, R Carranza-González
OBJECTIVE: Candiduria is increasingly frequent in hospitalized debilitated patients. We aimed to evaluate the approach of clinicians to candiduria in the oldest old, and its effect on clearance and mortality. MATERIAL AND METHODS: An observational study without intervention was carried out during 2012 and 2013 in three Spanish hospitals over patients with nosocomial candiduria aged 80 and over. Following a diagnostic algorithm, we assessed the appropriateness of antifungal therapy and analyzed the impact of the clinical approach (antifungal therapy, antibiotics discontinuation and catheter removal or replacement) on the outcome (mortality at 60 days and resolution, persistence or recurrence of candiduria)...
September 2018: Journal de Mycologie Médicale
M Yaralizadeh, P Abedi, F Namjoyan, M Fatahinia, S Nezamivand Chegini
BACKGROUND: Candida albicans may cause vaginal infections in women. The aim of this study was to compare the antifungal effect of Lawsonia inermis with that of clotrimazole on rats. METHODS: A total of 35female Wistar rats were randomly assigned into 5groups. Four groups were infected vaginally with C. albicans and one group was not (negative control). The four infected groups received the following treatments: two groups received vaginal creams of 2% or 4% of L...
September 2018: Journal de Mycologie Médicale
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