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Journal de Mycologie Médicale

L Pastrone, M-T Corsetti, L Depaoli, S Sampò, M Colonna, A Rocchetti
Herein we describe a 43 year-old Caucasian female patient with acute myeloid leukemia that developed an unconventional form of invasive Aspergillosis. For therapeutic reasons, a Groshong-type central venous catheter was positioned. Monitoring the patient's clinical conditions, positive values for C-reactive protein and galactomannan were correlated with a probably Aspergillosis. Surprisingly no pulmonary evidences were observed. Due to worsening conditions, she was re-hospitalized and a blood culture was performed, whom positivity resulted as the first clinical evidence of Aspergillus fumigatus...
October 23, 2018: Journal de Mycologie Médicale
A R Khosravi, S Alheidary, D Nikaein, N Asghari
Aspergillus fumigatus conidia are the most prevalent indoors fungal allergens. The interaction between Aspergillus antigens and lung epithelial cells (LECs) result in innate immune functions. The association between Aspergillus conidia and allergic reactions, like allergic bronchopulmonary aspergillosis (ABPA) and asthma have been repeatedly reported. Since conventional therapies for allergy and asthma are limited, finding new promising treatments are inevitable. This study was designed to evaluate the effect of A...
October 22, 2018: Journal de Mycologie Médicale
K Diongue, O Kébé, M D Faye, D Samb, M A Diallo, M Ndiaye, M C Seck, A S Badiane, S Ranque, D Ndiaye
Pityriasis versicolor (PV) is a superficial mycosis caused by yeast of the genus Malassezia. The most common isolated Malassezia species in PV lesions differ among M. furfur, M. globosa and M. sympodialis. We purpose to determine the distribution of Malassezia species in PV patients at the seafarers' medical service in Dakar, Senegal and to examine whether any association between identified Malassezia species and patients' profile. From May 2017 to August 2017, first a questionnaire was filled to get informative data before collection of skin scrapings taken from most scaly site using sterile scalpel blade and application of scotch® for direct examination (DE)...
October 16, 2018: Journal de Mycologie Médicale
J Zhang, J Tan, L Yang, Y He
OBJECTIVES: To compare the in vitro interactions between tacrolimus (TAC)/triamcinolone acetonide (TRI) with itraconazole (ITC), terbinafine (TRB), bifonazole (BIZ), and amorolfine (AMF) in 28 clinical dermatophyte isolates, including 13 Trichophyton rubrum, 6 Trichophyton mentagrophytes, 5 Microsporum canis, and 4 Epidermophyton floccosum strains. MATERIALS AND METHODS: The interactions between TAC or TRI with antifungal agents were tested according to the microdilution checkerboard technique adapted from the CLSI M38-A2 microdilution method...
October 15, 2018: Journal de Mycologie Médicale
K Pakshir, H Fakhim, A Vaezi, J F Meis, M Mahmoodi, K Zomorodian, J Javidnia, S Ansari, F Hagen, H Badali
OBJECTIVE: Cryptococcosis is a major opportunistic fungal infection caused by members of the genus Cryptococcus, mainly those belonging to the Cryptococcus neoformans/Cryptococcus gattii species complexes. Here, we report a comprehensive molecular epidemiological study of the environmental distribution of Cryptococcus isolates in Shiraz, Iran with review of litreature. METHOD: A total of 406 samples were obtained from Eucalyptus trees and 139 samples from pigeon droppings...
October 12, 2018: Journal de Mycologie Médicale
S Aghaei-Gharehbolagh, M Shams-Ghahfarokhi, S Amanloo, M Razzaghi-Abyaneh
Ubiquitous airborne conidia of the genus Aspergillus are responsible for a diverse group of human disorders from allergy to life treating invasive aspergillosis and mycotoxicoses. The aim of this study was to determine the population structure of Aspergillus isolated from outdoor air in Tehran by comparing the nucleotide sequences of ITS region and the PCR-RFLP molecular method. Internal transcribed spacer domains of 47 Aspergillus spp. were amplified and sequenced and PCR products were digested individually with restriction enzymes TaqI and EcoRI...
October 3, 2018: Journal de Mycologie Médicale
J-M Bastide
No abstract text is available yet for this article.
September 24, 2018: Journal de Mycologie Médicale
S Gamarra, M S Chaves, M S Cabeza, D Macedo, F Leonardelli, D Franco, M Boleas, G Garcia-Effron
BACKGROUND: Rhizopus microsporus is one of the main causative agents of mucormycosis. These mycoses are mostly described as isolated cases involving uncontrolled diabetes mellitus or immunosuppressed patients. In this work we report a nosocomial outbreak of mucormycosis due to R. microsporum involving three young immunocompetent patients whom underwent arthroscopic anterior cruciate ligament reconstruction surgery in a seven-month time span. PROCEDURES: During the outbreak period, a total of 32 surgeries of this type were performed in the clinic (mucormycosis prevalence of 9...
September 22, 2018: Journal de Mycologie Médicale
S Otašević, S Momčilović, M Petrović, O Radulović, N M Stojanović, V Arsić-Arsenijević
OBJECTIVE: The aim of this study was to evaluate the effectiveness of an alternative treatment in a form of recommended diet modification during and after conventional treatment with antifungals in patients with a chronic form of intestinal Candida overgrowth (ICOG). METHODS: The study included patients with ICOG divided in two subgroups: patients treated with nystatin and recommended diet regime (study group-SG) and the patients treated only with nystatin (control group-CG)...
August 27, 2018: Journal de Mycologie Médicale
S-Y-A-S-A Fattah, F Hariri, R Ngui, S-I-S Husman
Mucormycosis is a rare fungal infection and high mortality that commonly affects patients with the weakened immune system. We present an unusual case of tongue necrosis probably due to the healthcare-associated mucormycosis (HCM) in a diabetic patient. Although cannot be proved with certainty, we surmise that intubation as a risk factor in our case. The diagnosis was confirmed by histopathological examination (HPE) of the necrotic tissue specimen. The patient was responded well to lipid complex amphotericin B (250mg) regime after surgery...
September 2018: Journal de Mycologie Médicale
C Imbert, C Hennequin, A Coste
No abstract text is available yet for this article.
September 2018: Journal de Mycologie Médicale
S T Pote, U Khan, K K Lahiri, M S Patole, M R Thakar, S R Shah
Onychomycosis is the most common infection of the toe-nails or finger-nails and it may be caused by a large variety of fungal species. Achaetomium species which belong to the phylum Ascomycota (Family Chaetomiaceae), are usually soil saprophytes or endophytic fungi which have been rarely reported as human or animal pathogens. Here, we report a case of onychomycosis caused by Achaetomium strumarium in a healthy person who showed involvement of all fingers of both hands with yellowish brown discoloration. The causative agent isolated was identified as Achaetomium species by morphology, colony morphometry and growth at high temperature and as A...
September 2018: Journal de Mycologie Médicale
Khadija Bouksir, Mohamed Kazzaz, Hanie Fassi Fehri, Hassan Bouziane, Hajar Bouksir, Fatima El Haskouri
We report a case of onychomycosis caused by Monascus ruber from 57-year old women. The diagnosis was based on culture morphological characteristics on Sabouraud's Dextrose agar one with antibacterial (chloramphenicol) and the other with cycloheximide. The identification of specie was confirmed by DNA sequencing.
September 2018: Journal de Mycologie Médicale
N W Sit, Y S Chan, S C Lai, L N Lim, G T Looi, P L Tay, Y T Tee, Y Y Woon, K S Khoo, H C Ong
OBJECTIVES: This study was conducted to evaluate the antidermatophytic activity of 48 extracts obtained from medicinal plants (Cibotium barometz, Melastoma malabathricum, Meuhlenbeckia platyclada, Rhapis excelsa, Syzygium myrtifolium, Vernonia amygdalina) and marine algae (Caulerpa sertularioides, Kappaphycus alvarezii) against Trichophyton rubrum and Trichophyton interdigitale (ATCC reference strains), and the cytotoxicity using African monkey kidney epithelial (Vero) cells. Active plant extracts were screened for the presence of phytochemicals and tested against clinical isolates of Trichophyton tonsurans...
September 2018: Journal de Mycologie Médicale
S Smaoui, K Ennouri, A Chakchouk-Mtibaa, I Sellem, K Bouchaala, I Karray-Rebai, L Mellouli
A Streptomyces sp. strain TN71 was isolated from Tunisian Saharan soil and selected for its antimicrobial activity against phytopathogenic fungi. In an attempt to increase its anti-Fusarium oxysporum activity, GYM+S (glucose, yeast extract, malt extract and starch) culture medium was selected out of five different production media. Plackett-Burman design (PBD) was used to select yeast extract, malt extract and calcium carbonate (CaCO3 ) as parameters having significant effects on antifungal activity, and a Box-Behnken design was applied for further optimization...
September 2018: Journal de Mycologie Médicale
S Das, G Rai, R A Tigga, S Srivastava, P K Singh, R Sharma, S Datt, N P Singh, S A Dar
Candida auris has emerged as the multi-drug resistant non-albican candida species in critically ill patients admitted to intensive care units (ICU) causing bloodstream and other infections. It has often been misidentified as Candida famata, Candida sake, Rhodotorula glutinis, or Saccharomyces cerevisiae and Candida haemulonii by automated identification systems. We, in this study, discuss three patients who acquired Candida auris infection after 15 to 20days of their stay in medical ICU. Medical equipment, use of multiple antibiotics, and poor hand hygiene are the most probable predisposing factors attributing to its colonization at multiple anatomical sites leading to bloodstream infection...
September 2018: Journal de Mycologie Médicale
H F Z Touil, Z Boucherit-Otmani, K Boucherit
BACKGROUND: Invasive fungal infections are an emerging health problem worldwide. They are responsible for a significant rate of morbidity and mortality. Infections caused by Candida albicans involve proliferation of biofilms on biotic or abiotic surface. These adherent communities exhibit characteristics distinct from planktonic cells such as the ability to tolerate high concentrations of antifungal. OBJECTIVE: The object of our study was focused on the determination of the susceptibility to amphotericin B, caspofungin, voriconazole and two antifungal combinations (amphotericin B/caspofungin and amphotericin B/voriconazole) of both planktonic and sessile cells of C...
September 2018: Journal de Mycologie Médicale
A L Bidaud, A Chowdhary, E Dannaoui
Candida auris is an emerging fungal pathogen responsible for nosocomial invasive infection outbreaks on five continents. Large healthcare-related outbreaks of C. auris infection and colonization have been reported from different countries. Whole genome sequence analysis identified strong phylogeographic C. auris clades specific to particular geographical areas suggesting transmission of particular clades within countries. However, the mode of transmission within the healthcare environment is not clear and is likely to be multifactorial...
September 2018: Journal de Mycologie Médicale
G Hazirolan, N Koçak, A Karagöz
INTRODUCTION: Trichosporon asahii is the most common species that causes trichosporonosis. MATERIALS AND METHODS: In the present study, a collection of 68T. asahii strains recovered from hospitalized patients urine samples between 2011 and 2016 was examined. T. asahii strains were identified by sequencing the intergenic spacer 1 region (IGS1) and genotyped. In addition, proteinase, phospholipase, esterase, haemolytic activity, and biofilm formation of a total of T...
September 2018: Journal de Mycologie Médicale
S K Deshmukh, S A Verekar, Y G Chavan
Forty soil samples were collected from seven sites in the vicinity of Sambhar lake Rajasthan, India and screened for the presence of keratinophilic fungi using hair baiting techniques for isolation. Seventeen isolates were recovered and identified. The cultures were identified by recognition of their macro- and micro- morphological features. Their identification was confirmed by BLAST using ITS1-5.8S-ITS2 rDNA region and sequences have been deposited in NCBI data base. A total of 34 species belonging to 29 genera were isolated...
September 2018: Journal de Mycologie Médicale
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