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Atsushi Kohga, Kiyoshige Yajima, Takuya Okumura, Kimihiro Yamashita, Jun Isogaki, Kenji Suzuki, Akira Komiyama, Akihiro Kawabe
Isolated cecal necrosis (ICN) is a rare condition which is developed under decreased mesenteric perfusion. Only a few dozen cases of ICN have been reported previously. The patient was a 59-year-old male with a previous history of atrial fibrillation. He presented to our emergency room with the chief complaint of lower abdominal pain. Computed tomography imaging revealed a dilated cecum and presence of free air. With a preoperative diagnosis of perforation of the cecum; an urgent surgery was conducted. Intraoperative findings revealed an ischemic change of the cecum and a laparoscopic-assisted ileocecal resection was performed...
January 10, 2019: Medicina
Nguyen Thuy Duong, Nguyen Thy Ngoc, Nguyen Tran Minh Thang, Bach Thi Hoai Phuong, Nguyen Thanh Nga, Nguyen Doan Tinh, Do Hai Quynh, Nguyen Dang Ton, Nong Van Hai
Background and objective: Gout is a common form of inflammatory arthritis caused by the crystallization of uric acid. Previous studies have demonstrated that the genetic predisposition of gout varies in different ethnic populations. However the association study of genetic variants with gout remains unknown in the Vietnamese population. Our study aimed to assess the relationship between polymorphisms in ABCG2 and SLC22A12 and gout susceptibility in Vietnamese. Materials and methods: Genomic DNA was extracted from blood of a total of 170 patients with gout and 351 healthy controls...
January 7, 2019: Medicina
Akbar Moradi, Esmaeil Sadri Damirchi, Mohammad Narimani, Samad Esmaeilzadeh, Inga Dziembowska, Liane B Azevedo, Wagner Luiz do Prado
Background and objective: There is an increased interest in exploring the association between fitness components with cognitive development in children in recent years. One of the scopes is to find the best exercise prescription to enhance health and cognition. Most of the studies so far have focused on cardiorespiratory fitness with little evidence on other fitness components. The present study aimed to explore the association between physical fitness (PF) and motor fitness (MF) with cognitive performance in children...
January 4, 2019: Medicina
Atsushi Kohga, Kiyoshige Yajima, Takuya Okumura, Kimihiro Yamashita, Jun Isogaki, Kenji Suzuki, Katsuaki Muramatsu, Akira Komiyama, Akihiro Kawabe
Background and objective : In patients with acute appendicitis (AA), preoperative computed tomography (CT) findings suggesting development of intraabdominal abscess (IAA) had not been widely used. The aim of this study was to investigate the preoperative clinical and radiological factors that predict the development of a postoperative IAA in patients with AA who were treated by laparoscopic appendectomy (LA). Methods : Two hundred and sixteen patients with pathologically proven AA underwent LA between January 2013 and March 2018 in our department...
January 4, 2019: Medicina
Dharam Persaud-Sharma, Joseph Burns, Jeran Trangle, Grettel Castro, Noel Barengo, Sabyasachi Moulik, Juan Manuel Lozano
Background and objectives: Glial brain cancers affect nearly 20,000 individuals in the United States (USA) annually. SEER database data exploring the relationship between race and gliomas is now available and have shown that cerebral gliomas occur at a higher frequency in Caucasian men. However, such analyses did not include demographic data specific to the state of Florida. This study assessed the association between race and glial vs. non-glial Central Nervous System (CNS) cancers in Florida, USA. Materials and Methods: This case-control study utilized the Florida Cancer Data Registry (FCDS), in which race was considered the exposure and development of glioma as the measured outcome...
January 4, 2019: Medicina
Linda Rautiainen, Jana Pavare, Ilze Grope, Peteris Tretjakovs, Dace Gardovska
Background and objectives: In children, acute infection is the most common cause of visits to the emergency department. Although most of them are self-limiting, mortality due to severe bacterial infections (SBI) in developed countries is still high. When the risk of serious bacterial infection is too high to ignore, yet too low to justify admission and hospital observation, clinicians try to improve diagnostic accuracy by performing various laboratory tests. The aim of the study was to investigate whether an early inflammatory cytokine and chemokine panel can add information in diagnostics of SBI and assessment of efficacy of early therapies in hospitalized children with fever...
January 3, 2019: Medicina
Gökhan Sadi, Gamze Şahin, Aykut Bostancı
Background and objectives: Diabetes mellitus is a disease of insulin deficiency or its inability of usage by the target tissues leading to impairment of carbohydrate, lipid, and protein metabolisms. Resveratrol, having robust anti-inflammatory and anti-oxidant properties, has a high potential to treat or prevent the pathogenesis of diseases. This study was conducted to reveal the relationship between diabetes-induced oxidative stress and tissue inflammation with changes in main enzymatic antioxidants ( cat, sod, gpx, and gst ) and the components of the insulin signaling pathway ( insulin Rβ, irs -1, pi3k, akt , mtor ) in kidney tissues...
December 31, 2018: Medicina
Marja H Leppänen, Pontus Henriksson, Hanna Henriksson, Christine Delisle Nyström, Francisco Jesus Llorente-Cantarero, Marie Löf
Background and objectives : There is a lack of studies investigating associations of physical activity level (PAL) and activity energy expenditure (AEE) using the doubly-labeled water (DLW) method with body composition and physical fitness in young children. Thus, we aimed to examine cross-sectional associations of PAL and AEE with body composition indices and physical fitness components in Swedish preschool children. Materials and methods: PAL was calculated as total energy expenditure measured using DLW divided by the predicted basal metabolic rate in 40 children aged 5...
December 27, 2018: Medicina
Fatih Doğanay, Rohat Ak, Halil Alışkan, Serdar Abut, Engin Sümer, Özge Onur
Background and objectives : Although there are several hypotheses about the mechanism of action, intravenous lipid emulsion (ILE) therapy has been shown to be effective in the treatment of toxicities due to local anaesthetics and many lipophilic drugs. In this study, we had hypothesized that ILE therapy might also be effective in preventing mortality and cardiorespiratory depressant effects due to propofol intoxication. Materials and methods : Twenty-eight Sprague-Dawley adult rats were randomly divided into four groups...
December 25, 2018: Medicina
Cristina Moraru, Manuela Maria Mincea, Mirela Frandes, Bogdan Timar, Vasile Ostafe
Background and objectives: Erratic results have been published concerning the influence of the dietary supplement chitosan used as a complementary remedy to decrease the body weight of overweight and obese people. The published articles mention as secondary possible benefits of usage of chitosan the improvement of blood pressure and serum lipids status. We performed a meta-analysis evaluating body weight, body mass index, total cholesterol, high density lipoprotein cholesterol, low density lipoprotein cholesterol, triglycerides, systolic and diastolic blood pressure among overweight and obese patients...
December 12, 2018: Medicina
Samuel P Trethewey, Gareth I Walters
Idiopathic pulmonary fibrosis (IPF) is a chronic interstitial lung disease characterised by a progressive and irreversible decline in lung function, which is associated with poor long-term survival. The pathogenesis of IPF is incompletely understood. An accumulating body of evidence, obtained over the past three decades, suggests that occupational and environmental exposures may play a role in the development of IPF. This narrative literature review aims to summarise current understanding and the areas of ongoing research into the role of occupational and environmental exposures in the pathogenesis of IPF...
December 10, 2018: Medicina
Viktoras Rudžianskas, Erika Korobeinikova, Milda Rudžianskienė, Evelina Jaselskė, Diana Adlienė, Severina Šedienė, Ilona Kulakienė, Evaldas Padervinskis, Nemira Jurkienė, Elona Juozaitytė
Background and objectives: Induction chemotherapy (ICT) before definitive chemoradiation (CRT) gives high response rates in locally advanced squamous cell carcinoma of the head and neck (LA-SCCHN). However, pre-ICT gross tumor volume (GTV) for radiotherapy (RT) planning is still recommended. As 18 F-FDG PET/CT has an advantage of biological tumor information comparing to standard imaging methods, we aimed to evaluate the feasibility of 18 F-FDG PET/CT-based post-ICT GTV delineation for RT planning in LA-SCCHN and to assess the prognostic value of PET parameters: maximum standardized uptake value (SUVmax ), metabolic tumor volume (MTV) and total lesion glycolysis (TLG)...
December 10, 2018: Medicina
Giorgio Ciprandi, Paola Puccinelli, Cristoforo Incorvaia, Simonetta Masieri
Parietaria pollen is the most important cause of pollen allergies in the Mediterranean area, as Parietaria is widespread in this region. Many issues are associated with Parietaria allergy, including the duration of the pollen season (many doctors in fact believe that it lasts throughout the year), pollen load (which seems to be increasing over time), the impact of age (on IgE production and symptom severity), inflammatory changes (after pollen exposure), and the choice of allergen immunotherapy (AIT). In addition, molecular diagnostics allows for the defining of a correct diagnosis, differentiating between mere sensitization and true allergy...
December 7, 2018: Medicina
Minsung Sohn, Leesa Lin, Minsoo Jung
Background and objectives: It is now accepted that vaccination is a critical public health strategy in preventing child morbidity and mortality. Understanding factors that promote vaccination is a critical first step. The objective of this study was to investigated associations of maternal decisional authority and media use on vaccination for children in six South and Southeast Asian countries. Materials and Methods: Data come from demographic and health surveys conducted in Bangladesh, Cambodia, Indonesia, Nepal, Pakistan, and the Philippines between 2011 and 2014 (N = 45,168 women)...
December 7, 2018: Medicina
Dominika Głąbska, Karolina Cackowska, Dominika Guzek
Background and objectives : Some publications indicate the possibility of the influence of meal nutritional value on results of bioelectrical impedance, and of the relation between the long-term carbohydrate intake and body composition. The aim of the presented study was to evaluate the influence of long-term intake of carbohydrates on body composition results assessed using the bioelectrical impedance of Caucasian young women with normal body mass, who were in the follicular phase of their menstrual cycle...
December 5, 2018: Medicina
Andrejus Černovas, Vidmantas Alekna, Marija Tamulaitienė, Rimantas Stukas
Introduction: Ageing is associated with several physical, psychological, and behavioral changes. These changes are closely related with general health problems and quality of life in old age. The CASP-19 multidimensional instrument was specially designed to measure quality of life in the elderly. The different language versions of this scale have been used in more than 20 countries. However, Lithuanian translation was not available. The objective of our study was to test psychometric properties of the Lithuanian version of the CASP-19 questionnaire...
December 5, 2018: Medicina
Urmo Kiitam, Lilita Voitkevica, Saima Timpmann, Inese Pontaga, Jaan Ereline, Eve Unt, Vahur Ööpik
Background and Objectives: Only a few studies have reported the pre-practice hydration status in soccer players (SPs) who train in a cool climate. The primary purpose of this study was to examine the hydration status of male semiprofessional SPs immediately before their regular training session in winter. The secondary purpose was to compare the urinary indices of the hydration status of Estonian and Latvian SPs. Materials and Methods: Pre-training urine samples were collected from 40 Estonian (age 22.1 ± 3...
December 5, 2018: Medicina
Michael W Retsky, Patrice Forget
A simple solution may exist for both the problem of sudden dementia and confusion after surgery in the elderly and the bimodal relapse pattern among breast cancer patients who were treated with a mastectomy. Systemic inflammation by a variety of mechanisms can induce tumor outgrowth from dormant states, such as single dormant cells and avascular micrometastases. This may also explain sudden confusion and dementia for the elderly after surgery. We propose that surgery-induced inflammation may be addressed by "protective anesthesia"...
December 3, 2018: Medicina
Pietro Ferrara, Lucia Stromillo, Luciana Albano
Background and objectives: Vaccination against bacterial pathogens is decisive for preventing invasive meningococcal disease and pediatricians play a pivotal role in vaccination compliance and coverage. The aim of this study was to investigate awareness, attitude, and practices toward the vaccine against Meningococcal B serogroup (4CMenB) among a sample of Italian pediatricians. Materials and Methods: A cross-sectional study was carried out using an online questionnaire from March to May 2015. Three multivariate logistic regression models were built to identify factors associated with the outcomes of interest...
December 3, 2018: Medicina
Hamid Reza Mozaffari, Elisa Zavattaro, Abas Abdolahnejad, Pia Lopez-Jornet, Neda Omidpanah, Roohollah Sharifi, Masoud Sadeghi, Mohammad Shooriabi, Mohsen Safaei
Immunoglobulins (IgA, IgG, and IgM) are significant anti-inflammatory factors. The meta-analysis aimed to assess the serum and salivary levels of Igs as more important immunoglobulins in patients affected by oral lichen planus (OLP) compared to the healthy controls. Four databases, including PubMed/Medline, Scopus, Web of Science, and Cochrane Library as well as Iranian databases were checked up to January 2018 without language restriction. The quality of each involved study was done using the Newcastle⁻Ottawa Quality Assessment Scale (NOS) questionnaire...
December 3, 2018: Medicina
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