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Psychiatria Danubina

Manon Fagniart, Christine Reynaert, Denis Jacques, Bries Lepièce, Nicolas Zdanowicz
BACKGROUND: Exposure to stress modifies the humoral and cellular immunity by the activation of the hypothalamic-pituitary-adrenal axis. On one hand, this psycho-immunological theory allows the analyse of links between immunity and depression. On the other hand, the correlation between the immune response, the clinical expression in major depressive disorder (MDD) and the gender was proven. Our analysis evaluates the influence of the gender and the level of depression severity on the cellular immune response associated with it...
September 2016: Psychiatria Danubina
Catherine Gigot, Christine Reynaert, Nicolas Zdanowicz
BACKGROUND: In a previous study, we compared the family relationships of patients hospitalized in a psychiatry unit from either psychiatric consultations or after passing emergency room (E.R.). The intensity of depression was statistically comparable in both groups. What distinguishes patients transiting emergencies is that their families and couples are more cohesive and adaptable. In this study, we compare both groups in terms of coping mechanisms and multidimensional health locus of control (MHLC)...
September 2016: Psychiatria Danubina
Thomas Dubois, Nicolas Zdanowicz, Christine Reynaert, Denis Jacques
BACKGROUND: Previous study shows that cellular immunity and family relationships are each correlated with the severity of depression and suggests that the psycho-immunological theory should look at the relation between immunity and family life. The aim of the present study based on the same sample is to investigate if similar correlations exist with humoral immunity. SUBJECTS AND METHOD: 498 inpatients with major depressive disorder were enrolled in an open-label trial...
September 2016: Psychiatria Danubina
Pauline Manceaux, Nicolas Zdanowicz
BACKGROUND: On the one hand, this psycho-immunological theory makes it possible to forge links between immunity and depression. On the other hand, we know that coping strategies are an important variable in the model of vulnerability to depression. Our study weighs the influence of cellular immunity and coping strategies on the severity of depression. SUBJECTS AND METHOD: 498 inpatients with major depressive disorder were enrolled in an open-label trial. In addition to a socio-demographic questionnaire, they answered a Cousson's coping test and the Beck Depression Inventory (BDI)...
September 2016: Psychiatria Danubina
Dominika Tobolska, Krzysztof Maria Wilczyński, Miłosz Lorek, Elżbieta Mazgaj, Krzysztof Krysta, Aneta Gawlik, Marek Krzystanek
INTRODUCTION: The hypothalamus-pituitary-adrenal axis (HPAA) plays a pivotal role in response to a range of external and internal factors often described as a "stress". Growing evidence in a literature, suggest various dysregulations of HPAA, in course of numerous mental disorders. Patients with schizophrenia and bipolar disorder seem to have elevated basal cortisol secretion, what might be caused by the diminution of glucocorticoid receptors' amount. It was of the interest if the cortisol concentrations in patients with diagnosed schizophrenia who underwent treatment, differs from healthy individuals...
September 2016: Psychiatria Danubina
Nicolas Zdanowicz, Thomas Dubois, Christine Reynaert, Denis Jacques, Pauline Manceaux
BACKGROUND: In a previous study, we investigated the risk of admission to emergency (ER) of depressed patients prior to their hospitalization in psychiatry in comparison with hospitalized patients transferred from the consultations department (Cdpt). In the present study, we compare among the same patients variables affecting the intensity of depression in each group. METHOD: All patients with Major depressive disorder admitted in our department through emergencies (N=146) or consultations (N=2172) between January 1, 2010 and December 31, 2012 were included in an open study...
September 2016: Psychiatria Danubina
Anaïs Bastide, Aloïse de Codt, Pauline Monhonval, Xavier Bongaerts, Juan Martin Tecco
BACKGROUND: Benzodiazepines (BZDs) are among the most widely prescribed drugs in developed countries. Since BZDs can produce tolerance and dependence even in a short time, their use is recommended for a very limited time. However, these recommendations have been largely disregarded. The chronic use of BZDs causes a number of serious side effects, i.e. cognitive impairment, falls, traffic accidents, dependence and tolerance. METHODS: We present the case of a 37 years old woman taking daily doses of 220 mg of bromazepam...
September 2016: Psychiatria Danubina
Cátia Jesus, Inês Jesus, Mark Agius
BACKGROUND: Osteoarthritis (OA) also called degenerative joint disease is the most common chronic condition of the joints that just in 2004, caused moderate to severe disability in 43.4 million of people. OA in Western populations is one of the most frequent causes of joint pain, loss of function and disability in adults. In the U.S. it is the second most common cause of work disability in men over 50 years of age, following ischaemic heart disease, and accounts for a higher number of hospitalizations when compared with rheumatoid arthritis (RA) each year...
September 2016: Psychiatria Danubina
Francesco Franza, Gabriella Carpentieri, Serena De Guglielmo, Vincenzo Fasano, Nicoletta Fiorentino, Mariangela Perito, Barbara Solomita, Gianfranco Del Buono
Patients with schizophrenia have profound and disabling cognitive deficits while negative symptoms represent a separate symptom domain, with respect to depression, neurocognition, and social cognition. Particularly, primary negative symptoms of schizophrenia represent a diagnostic and therapeutic challenge, In this study we try to evaluate the cognitive symptoms in 51 primary negative schizophrenic inpatients by the administration of simple, fast and understandable scales (MMSE, DSST, EpiTrack, PANSS cognitive factor)...
September 2016: Psychiatria Danubina
Giada Juli, Luigi Juli
Pharmacogenetics is a powerful tool to improve drug response and to maximize therapeutic efficacy and safety using genetic information of each individual. This review collects the available literature understanding the influence of heritability on an individual's drug metabolism.
September 2016: Psychiatria Danubina
Saigeet Eleti
BACKGROUND: Alzheimer's dementia is one of the most significant health burdens of the modern age in both industrialised and non-industrialised nations as it is a major cause of morbidity and functional impairment in the elderly. Currently there are no cures for progressive dementias, including Alzheimer's disease, and no treatments that would modify their progress. Intervention involves pharmacological treatment to temporarily relieve the symptoms, including three cholinesterase inhibitors and a noncompetitive NMDA antagonist, and the efficacy of these is widely debated...
September 2016: Psychiatria Danubina
Marilisa Amorosi
The National Plan of Action for Mental Health (PANSM), approved by the Conference of Regions has been from January 24 2013, being implemented by the Department of Mental Health Services. It requires a reorganization of the same, the functional the adoption of a methodology based on the Necessity of Working for projects which are Intervention-specific and differentiated, based on the evaluation of the need and patients and the implementation of care pathways. This implies a systemic approach by of the team, rather than a segmental working mode...
September 2016: Psychiatria Danubina
Maurilio Giuseppe Maria Tavormina, Giuseppe Tavormina, Eugenio Nemoianni, Francesco Franza, Immacolata d'Errico, Maria Grazia Spurio, Romina Tavormina, Nicolas Zdanowicz, Stephanie De Mesmaeker, Judit Harangozó, Anna Nyulászi, Tünde Bulyáki, Ivan Urlic, Andrea Russo, Mark Agius
Prejudice and stigma about mental illness is still present in society. Patients suffer both from the disease, and from the marginalization behavior exhibited by others towards them and their families. Psychiatric professionals may also become ill and suffer for the same reason. The authors of this international multicenter study have set themselves the question of whether there may be prejudice and/or stigma among psychiatric professionals towards their suffering colleagues, among patients towards nursing staff affected by the same disease and between patients themselves...
September 2016: Psychiatria Danubina
Denis Jacques, Christine Reynaert, Nicolas Zdanowicz
BACKGROUND: In the context of health care in Belgium, the psychological or psychiatric opinion of a multidisciplinary team is required in the assessment of bariatric surgery candidates. In clinical practice, a wide variety of liaison psychiatry assessment methods exist. SUBJECTS AND METHODS: On the basis of a post-operative psychiatric comorbidity case report and a literature review on "liaison psychiatry and bariatric surgery" we aim to identify opportunities for the systematization of bariatric pre-surgery psychiatric evaluation...
September 2016: Psychiatria Danubina
Krzysztof Krysta, Krzysztof Wilczyński, Jakub Paliga, Agnieszka Szczęsna, Marzena Wojciechowska, Ewa Martyniak, Marek Krzystanek
BACKGROUND: Virtual reality exposure therapy (VRET) is becoming a more and more popular treatment method for patients suffering from anxiety disorders. One of the VRET methods, wchich could be used for this group of patients is MOTEK CAREN system, however, so far no studies have been published on its implementation in psychiatric disorders. SUBJECT AND METHODS: Presented here is a case of a 45 year old woman suffering from anxiety disorders, who underwent a series of four subsequent trainings with the use of MOTEK CAREN system repeted once a week...
September 2016: Psychiatria Danubina
Maria Grazia Spurio
For a long time, terms like "mind" and "emotion" have rarely been taken into account, not even mentioned in the medical texts. The latest scientific researches, including the studies of Candace Pert, on the contrary, have emphasized that the entire body thinks, because every single cell hears, and feels emotions. The international researcher has discovered the endocrines and a vast number of neuropeptides, that work as an "information network" that interconnects the entire body, the "psychic" molecules are transmitted and travel, communicating information as in a circular and recursive body - mind mechanism...
September 2016: Psychiatria Danubina
Anton Grech
Mental Health Services in Malta are presently at crossroads, because they are in the stage of increasing and strengthening the community services and considering closing the main psychiatric inpatient facility and replacing it with a new hospital. For proper planning of such changes, and ideal approach is that of basing these plans on results of population based epidemiological findings on rate of mental illness and required care. Such studies are strongly recommended, and this approach has already been used in Malta a couple of years ago prior to establishing inpatient care for Eating Disorders...
September 2016: Psychiatria Danubina
Pierre Cole, Sebastien Weibel, Rosetta Nicastro, Roland Hasler, Alexandre Dayer, Jean-Michel Aubry, Paco Prada, Nader Perroud
BACKGROUND: Attention deficit hyperactivity disorder (ADHD) is associated with marked impairments in familial, social, and professional functioning. Although stimulant treatments can be effective in adult ADHD, some patients will respond poorly or not at all to medication. Previous studies demonstrated that cognitive behavioural therapy- (CBT) and dialectical behavior therapy- (DBT) oriented interventions are effective in reducing the burden of the disease, which is mainly marked by depression, interpersonal difficulties, low self-esteem, and low quality of life...
September 2016: Psychiatria Danubina
Rashid Zaman
Attention Deficit Hyperactivity Disorder (ADHD) is a common neuropsychiatric disorder that affects children and young adults. It results in significant impairment of their educational, social and occupational functioning and is associated economic societal burden. Whilst there are effective medications (such as methylphenidate) as well as some psychobehavioural therapies that can help with management of symptoms of ADHD, the former can have significant cardiac side effects, which limit their use. For number of patients these treatment options lack efficacy or are not acceptable...
September 2016: Psychiatria Danubina
Jeanne Lackamp, Rebecca Schlachet, Martha Sajatovic
BACKGROUND: Major depression disorder (MDD) is one of the most common mental disorders world-wide and is prevalent throughout the lifespan, with prevalence estimates of 1-5% in those 65 years of age and older. METHODS: The aim of this mini-review is to briefly summarize clinically relevant topics within the domain of later-life MDD. RESULTS: The mini-review presents an overview of epidemiology, complications of late life MDD, risk factors and clinical presentation, clinical assessment, general issues relevant to the treatment of the older adult with MDD, drug treatments, discussion of how medical complexity affects drug treatment and other treatment modalities...
September 2016: Psychiatria Danubina
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