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Croatian Medical Journal

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https://www.readbyqxmd.com/read/29740993/child-welfare-services-and-social-media-childhood-being-and-becoming-in-a-digital-society
#1
Siv-Britt Björktomta, Heidi Aarum Hansen
No abstract text is available yet for this article.
April 30, 2018: Croatian Medical Journal
https://www.readbyqxmd.com/read/29740992/influence-of-generic-reference-pricing-on-medicine-cost-in-slovenia-a-retrospective-study
#2
Nika Marđetko, Mitja Kos
AIM: To assess the impact of the generic reference pricing (GRP) system on the prices and cost of medicines in Slovenia approximately 8 years after its introduction in 2003 and before the implementation of the therapeutic reference pricing system. METHODS: A retrospective study of all medicines (N=789) included in the GRP system on January 31, 2012 was performed. Medicine prices and cost were analyzed between January 31, 2012 and December 31, 2013 after every update (N=11) of the maximum reimbursable price (MRP) and were compared to the price and cost on January 31, 2012 (index date)...
April 30, 2018: Croatian Medical Journal
https://www.readbyqxmd.com/read/29740991/decreased-tissue-oxygenation-in-newborns-with-congenital-heart-defects-a-case-control-study
#3
Petja Fister, Domen Robek, Darja Paro-Panjan, Uroš Mazić, Helena Lenasi
AIM: To compare regional tissue oxygenation (rSO2) in the brain, intestine, and kidney between newborns with and without congenital heart defects (CHD). METHODS: This observational case-control study was conducted at the Neonatal Department of Children's Hospital Ljubljana between December 2012 and April 2014. It included 35 newborns with CHD and 30 healthy age- and sex-matched controls. CHD were assessed echocardiographically and divided into acyanotic and cyanotic group...
April 30, 2018: Croatian Medical Journal
https://www.readbyqxmd.com/read/29740990/prevalence-of-multiple-sclerosis-in-croatia-data-from-national-and-non-governmental-organization-registries
#4
Tomislav Benjak, Vesna Štefančić, Željka Draušnik, Ivan Cerovečki, Dijana Roginić, Mario Habek, Sandra Mihel, Ranko Stevanović
AIM: To update the estimate of multiple sclerosis (MS) prevalence in Croatia using multiple epidemiological tools. METHODS: This level IV, epidemiological study gathered data from three national patient registries and one database of a non-governmental MS patients' organization. Data were extracted on all individuals who had undergone hospital MS treatment, consulted their primary health care providers about MS-related symptoms, been listed as having MS-related disability, or been members of the mentioned non-governmental organization in 2015...
April 30, 2018: Croatian Medical Journal
https://www.readbyqxmd.com/read/29740989/activity-of-fosfomycin-against-nosocomial-multiresistant-bacterial-pathogens-from-croatia-a-multicentric-study
#5
Luka Bielen, Robert Likić, Viktorija Erdeljić, Ivana Mareković, Nataša Firis, Marijana Grgić-Medić, Ana Godan, Ivan Tomić, Blaženka Hunjak, Alemka Markotić, Danijela Bejuk, Vladimira Tičić, Silvana Balzar, Branka Bedenić
AIM: To determine in vitro susceptibility of multiresistant bacterial isolates to fosfomycin. METHODS: In this prospective in vitro study (local non-random sample, level of evidence 3), 288 consecutively collected multiresistant bacterial isolates from seven medical centers in Croatia were tested from February 2014 until October 2016 for susceptibility to fosfomycin and other antibiotics according to Clinical and Laboratory Standards Institute methodology. Susceptibility to fosfomycin was determined by agar dilution method, while disc diffusion was performed for in vitro testing of other antibiotics...
April 30, 2018: Croatian Medical Journal
https://www.readbyqxmd.com/read/29740988/suppression-of-the-interleukin-1%C3%A3-induced-inflammatory-response-of-human-chang-liver-cells-by-acute-and-subacute-exposure-to-alcohol-an-in-vitro-study
#6
Katharina Mörs, Shinwan Kany, Jason-Alexander Hörauf, Nils Wagner, Claudia Neunaber, Mario Perl, Ingo Marzi, Borna Relja
AIM: To evaluate protective immunosuppressive dose and time-dependent effects of ethanol in an in vitro model of acute inflammation in human Chang liver cells. METHOD: The study was performed in 2016 and 2017 in the research laboratory of the Department of Trauma, Hand and Reconstructive Surgery, the University Hospital of the Goethe-University Frankfurt. Chang liver cells were stimulated with either interleukin (IL)-1β or IL-6 and subsequently treated with low-dose ethanol (85 mmol/L) or high-dose ethanol (170 mmol/L) for one hour (acute exposure) or 72 hours (subacute exposure)...
April 30, 2018: Croatian Medical Journal
https://www.readbyqxmd.com/read/29740987/science-communication-to-the-public
#7
EDITORIAL
Slobodan Vukičević, Zvonko Kusić, Lovorka Grgurević
No abstract text is available yet for this article.
April 30, 2018: Croatian Medical Journal
https://www.readbyqxmd.com/read/29498496/re-thinking-knowledge-landscapes-in-the-context-of-grounded-aboriginal-theory-and-online-health-communication
#8
Kishan Kariippanon, Kate Senior
No abstract text is available yet for this article.
February 28, 2018: Croatian Medical Journal
https://www.readbyqxmd.com/read/29498495/h-index-in-medicine-is-driven-by-original-research
#9
Jan K Nowak, Karol Lubarski, Lukasz M Kowalik, Jaroslaw Walkowiak
AIM: To investigate the contribution of selected types of articles to h-indices of medical researchers. METHODS: We used the Web of Science to export the publication records of various members from 26 scientific medical societies (13 European, 13 North American) associated with 13 medical specialties. Those included were presidents (n=26), heads of randomly chosen committees (n=52), and randomly selected members of those committees (n=52). Publications contributing to h-index were categorized as research articles, reviews, guidelines, meta-analyses, or other published work...
February 28, 2018: Croatian Medical Journal
https://www.readbyqxmd.com/read/29498494/potential-hot-spot-for-de-novo-mutations-in-ptch1-gene-in-gorlin-syndrome-patients-a-case-report-of-twins-from-croatia
#10
Vesna Musani, Petar Ozretić, Diana Trnski, Maja Sabol, Sanja Poduje, Mateja Tošić, Mirna Šitum, Sonja Levanat
We describe a case of twins with sporadic Gorlin syndrome. Both twins had common Gorlin syndrome features including calcification of the falx cerebri, multiple jaw keratocysts, and multiple basal cell carcinomas, but with different expressivity. One brother also had benign testicular mesothelioma. We propose this tumor type as a possible new feature of Gorlin syndrome. Gorlin syndrome is a rare autosomal dominant disorder characterized by both developmental abnormalities and cancer predisposition, with variable expression of various developmental abnormalities and different types of tumors...
February 28, 2018: Croatian Medical Journal
https://www.readbyqxmd.com/read/29498493/effect-of-antiepileptic-drug-comedication-on-lamotrigine-concentrations
#11
Mila Lovrić, Ivana Čajić, Željka Petelin Gadže, Iva Klarica Domjanović, Nada Božina
AIM: To estimate the effect size of concomitant antiepileptic therapy on the concentrations of lamotrigine, a drug often prescribed in combination with other antiepileptic drugs (AED), which can act as enzyme inducers or inhibitors. METHODS: A total of 304 patients with epilepsy, aged 18-70 years, were divided into a lamotrigine monotherapy group and groups receiving lamotrigine with AEDs that act as enzyme inducers, enzyme inhibitors, or both. We compared lamotrigine monotherapy serum concentrations with those where lamotrigine was administered with a metabolic inhibitor valproate, metabolic inducers carbamazepine, oxcarbazepine, phenobarbital, phenytoin, or topiramate, and both an inducer and an inhibitor...
February 28, 2018: Croatian Medical Journal
https://www.readbyqxmd.com/read/29498492/disease-characteristics-and-causes-of-early-and-late-death-in-a-group-of-croatian-patients-with-systemic-lupus-erythematosus-deceased-over-a-10-year-period
#12
Ivan Padjen, Mislav Cerovec, Marijan Erceg, Miroslav Mayer, Ranko Stevanović, Branimir Anić
AIM: To assess the causes of early death (ED) and late death (LD) in patients with systemic lupus erythematosus (SLE) and determine the features of deceased SLE patients followed-up in a single Croatian tertiary hospital center, because little if any data on causes of death (CODs) in SLE patients are available for Croatia. METHOD: We identified SLE patients regularly followed-up at the Division of Clinical Immunology and Rheumatology, University Hospital Center Zagreb, who died from 2002 to 2011...
February 28, 2018: Croatian Medical Journal
https://www.readbyqxmd.com/read/29498491/explore-dream-discover
#13
EDITORIAL
Ana Marušić, Matko Marušić
No abstract text is available yet for this article.
February 28, 2018: Croatian Medical Journal
https://www.readbyqxmd.com/read/29308835/concepts-and-definitions-of-health-and-health-related-values-in-the-knowledge-landscapes-of-the-digital-society
#14
Anna Lydia Svalastog, Doncho Donev, Nina Jahren Kristoffersen, Srećko Gajović
No abstract text is available yet for this article.
December 31, 2017: Croatian Medical Journal
https://www.readbyqxmd.com/read/29308834/severe-acrocyanosis-precipitated-by-cold-agglutinin-secondary-to-infection-with-mycoplasma-pneumoniae-in-a-pediatric-patient
#15
Bernadett Mosdósi, Zoltán Nyul, Arnold Nagy, Kata Bölcskei, Tamás Decsi, Zsuzsanna Helyes
This is the first report describing a severe form of cold agglutinin-induced acrocyanosis with cutaneous necrosis after Mycoplasma infection in a 9-year-old patient without any other severe symptoms and laboratory alterations. We also present the results of two non-invasive methods used to determine the viability of tissues, degree of tissue perfusion impairment, and the responsiveness of the microvasculature. Laser Doppler flowmetry and laser speckle contrast imaging, both suitable to measure tissue blood perfusion non-invasively, have been used in the diagnosis and follow-up of various peripheral vascular diseases...
December 31, 2017: Croatian Medical Journal
https://www.readbyqxmd.com/read/29308833/severe-bleeding-complications-and-multiple-kidney-transplants-in-a-patient-with-tuberous-sclerosis-complex-caused-by-a-novel-tsc2-missense-variant
#16
Stela Živčić-Ćosić, Karin Mayer, Gordana Đorđević, Mark Nellist, Marianne Hoogeveen-Westerveld, Damir Miletić, Sanjin Rački, Hanns-Georg Klein, Zlatko Trobonjača
We presented an extremely severe case of tuberous sclerosis complex (TSC) in a female patient with recurring, life-threatening bleeding complications related to renal angiomyolipomas. Massive intratumoral hemorrhage required surgical removal of both angiomyolipomatous kidneys and kidney transplantation. During the follow-up period, the patient developed severe metrorrhagia that eventually led to hysterectomy and salpingo-oophorectomy. Bleeding from the operative sites caused the loss of the first kidney transplant received from the mother, and immediate hemorrhagic shock led to the loss of the second, cadaveric kidney allograft...
December 31, 2017: Croatian Medical Journal
https://www.readbyqxmd.com/read/29308832/comparison-of-risk-pci-grace-timi-risk-scores-for-prediction-of-major-adverse-cardiac-events-in-patients-with-acute-coronary-syndrome
#17
COMPARATIVE STUDY
Tamara Jakimov, Igor Mrdović, Branka Filipović, Marija Zdravković, Aleksandra Djoković, Saša Hinić, Nataša Milić, Branislav Filipović
AIM: To compare the prognostic performance of three major risk scoring systems including global registry for acute coronary events (GRACE), thrombolysis in myocardial infarction (TIMI), and prediction of 30-day major adverse cardiovascular events after primary percutaneous coronary intervention (RISK-PCI). METHODS: This single-center retrospective study involved 200 patients with acute coronary syndrome (ACS) who underwent invasive diagnostic approach, ie, coronary angiography and myocardial revascularization if appropriate, in the period from January 2014 to July 2014...
December 31, 2017: Croatian Medical Journal
https://www.readbyqxmd.com/read/29308831/anemia-hypoalbuminemia-and-elevated-troponin-levels-as-risk-factors-for-respiratory-failure-in-patients-with-severe-exacerbations-of-chronic-obstructive-pulmonary-disease-requiring-invasive-mechanical-ventilation
#18
Gordana Pavliša, Marina Labor, Hrvoje Puretić, Ana Hećimović, Marko Jakopović, Miroslav Samaržija
AIM: To determine in-hospital and post-discharge mortality, readmission rates, and predictors of invasive mechanical ventilation (IMV) in patients treated at intensive care unit (ICU) due to acute exacerbations of chronic obstructive pulmonary disease (AECOPD). METHODS: A retrospective observational cohort study included all patients treated at a respiratory ICU for AECOPD during one year. A total of 62 patients (41 men) with mean age 68.4±10.4 years were analyzed for outcomes including in-hospital and post-discharge mortality, readmission rates, and IMV...
December 31, 2017: Croatian Medical Journal
https://www.readbyqxmd.com/read/29308830/starling-forces-drive-intracranial-water-exchange-during-normal-and-pathological-states
#19
Andreas A Linninger, Colin Xu, Kevin Tangen, Grant Hartung
AIM: To quantify the exchange of water between cerebral compartments, specifically blood, tissue, perivascular pathways, and cerebrospinal fluid-filled spaces, on the basis of experimental data and to propose a dynamic global model of water flux through the entire brain to elucidate functionally relevant fluid exchange phenomena. METHODS: The mechanistic computer model to predict brain water shifts is discretized by cerebral compartments into nodes. Water and species flux is calculated between these nodes across a network of arcs driven by Hagen-Poiseuille flow (blood), Darcy flow (interstitial fluid transport), and Starling's Law (transmembrane fluid exchange)...
December 31, 2017: Croatian Medical Journal
https://www.readbyqxmd.com/read/29308829/the-recent-state-of-a-hundred-years-old-classic-hypothesis-of-the-cerebrospinal-fluid-physiology
#20
EDITORIAL
Darko Orešković, Milan Radoš, Marijan Klarica
No abstract text is available yet for this article.
December 31, 2017: Croatian Medical Journal
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