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Turkish Neurosurgery

Murat Sayin, Gülşen Seren Gürgen, Sevgi Sıdıka Sayin, Gönül Güvenç, Nurullah Yüceer
AIM: Migraine headaches are a common and significant issue experienced by women during pregnancy. However, treating migraines during pregnancy and post-pregnancy is challenging because of the risks that migraine medications pose to the fetus and infant. Few studies have investigated the effect of triptans during pregnancy, and controlled studies are not available. Our research aimed to investigate the impact of rizatriptan on neural tube development using early chick embryos as a model organism...
May 7, 2018: Turkish Neurosurgery
Kerem Mazhar Ozsoy, Kadir Oktay, Yurdal Gezercan, Nuri Eralp Cetinalp, Ali Ihsan Okten, Tahsin Erman
AIM: The management of thoracolumbar burst fractures without neurological symptoms remains controversial. Certain authors have suggested that vertebroplasty and kyphoplasty are contraindicated in patients with burst fractures. However, we performed vertebroplasty to treat intractable pain, reduce surgical risk and achieve early mobilization. MATERIAL AND METHODS: Twelve patients older than 65 years of age with thoracolumbar fractures without neurological deficits underwent vertebroplasty...
May 4, 2018: Turkish Neurosurgery
Irem Maro Kiris
Architectural production has been influenced by a variety of sources. Forms derived from nature, biology and live organisms, had often been utilised in art and architecture. Certain features of the human anatomy had been reflected in design process in various ways, as imitations, abstractions, interpretations of the reality. The correlation of ideal proportions had been investigated throughout centuries. Scholars, art historians starting with Vitruvius from the world of ancient Roman architecture, described the human figure as being the principal source of proportion among the classical orders of architecture...
May 4, 2018: Turkish Neurosurgery
Yi-Zheng Wang, Jing Chen, Yu-Lian Fang, Chun-Quan Cai
Intracranial medulloepithelioma is extremely rare and highly malignant in central nervous system. It is a kind of fast-growing tumor and shows a propensity to spread widely throughout the central nervous system. It commonly occurs in infants and young children. We reported a rare case of 2 years old female child with a huge mass diagnosed as medulloepithelioma. Though radiological examination was characteristic for the neoplasm, it was not enough to make a definite diagnosis. Combining with histopathological examination was contributing to diagnose medulloepithelioma and differentiate it from other central nervous system tumors...
April 26, 2018: Turkish Neurosurgery
Nese Keser, Osman Kula, Merih Is, Ismail Yardimcioglu
AIM: Although it is well known that the occipital artery (OA) originates from the external carotid artery (ECA), the incidence of variations remains unknown. In our study, we investigated the prevalence of anomalously originating OA using angiography in a group of Turkish individuals. MATERIAL AND METHODS: The images recorded in the picture archiving and communication system for a total of 114 patients, in which the whole vertebral artery, as well as the ECA and its branches, were visualized, were retrospectively reviewed...
April 26, 2018: Turkish Neurosurgery
Ayse Sahin, Mustafa Kilic, Nazan Dalgic
Intradural spinal cord abscesses are rare infections in early childhood and usually result from pre-existing congenital anomalies of the spinal column. The formation of abscess may be the result of hematogenous spread. It is treated by surgical and parenteral antibiotic treatment, but some special cases may require additional treatments. This article presents a 4-year-old male patient who was operated because of spina bifida (meningocele and tethered cord) at the external center, and upon complains of not being able to walk after one month, he was operated with the diagnosis of spinal intradural abscess and referred to us to continue his treatment...
April 26, 2018: Turkish Neurosurgery
İnan Gezgin, Cem Öziç
AIM: Zinc oxide nanoparticles are flexible platforms for biotechnology and biomedical applications. To investigate the expression level of the DR4, DR5, OPG, DcR1 and DcR2 in brain tissue. MATERIAL AND METHODS: The expression of DR4, DR5, OPG, DcR1, DcR2 and β-actin were measured through RT-PCR and western blotting in brain tissues of all three groups. The mRNA expression levels of DR4, DR5, OPG, DcR1 and DcR2 was investigated by using the RT-PCR and western blotting methods...
April 24, 2018: Turkish Neurosurgery
Sevki Gok, Mehmet Zafer Berkman, Eyup Baykara
Composite Hemangioendothelioma (CHE) is a very rare, low-grade malignant vascular tumor. It is most commonly seen as one or more nodules on both sides of the fingers and toes. This tumor is rarely settled in the paraspinal muscles. The age of onset is usually between the ages of 21 and 72 (1), with average age of 39.5-41 years. The treatment is gross total removal of the lesion. The definitive diagnosis is made histopathologically. Our case was a 54-year-old male patient. He had a complaint of low back pain...
April 24, 2018: Turkish Neurosurgery
Deniz Kargin, Özgür İsmail Türk, Akif Albayrak, Avni İlhan Bayhan, Mehmet Akif Kaygusuz
AIM: Lenke Type 1, the main thoracic curve type, is the most common spinal curve pattern in adolescent idiopathic scoliosis (AIS). The aim of this study was to compare the postoperative changes of both sagittal spinal and spinopelvic parameters in patients with Lenke Type 1 AIS who underwent selective and non-selective fusion surgery. MATERIAL AND METHODS: We conducted a retrospective study among 53 Lenke Type 1 AIS patients who underwent corrective surgery at our centre between 2006 and 2012...
April 9, 2018: Turkish Neurosurgery
Goktekin Tenekeci, Yavuz Basterzi, Sakir Unal, Alper Sari, Yavuz Demir, Celal Bagdatoglu, Bahar Tasdelen
AIM: Bilateral rotation flaps are considered the workhorse flaps in reconstruction of myelomeningocele defects. Since the introduction of perforator flaps in the field of reconstructive surgery, perforator flaps have been used increasingly in the reconstruction of various soft tissue defects all over the body because of their appreciated advantages. The aim of this study was to compare the complications and surgical outcomes between bilateral rotation flaps and dorsal intercostal artery perforator (DICAP) flaps in the soft tissue reconstruction of myelomeningocele defects...
April 9, 2018: Turkish Neurosurgery
Numan Karaarslan, Ibrahim Yilmaz, Feride Sinem Akgun, Tezcan Caliskan, Hanefi Ozbek, Ozkan Ates
AIM: This study discusses the management of patients with the syndrome of inappropriate antidiuretic hormone secretion (SIADH), developed after subarachnoid hemorrhage, in a comparative manner in light of the literature. MATERIAL AND METHODS: Without country or language restrictions, articles with high evidential value found in electronic databases were compared to our patients' data. RESULTS: After the literature review, three articles were included for systematic evaluation...
April 9, 2018: Turkish Neurosurgery
Yener Akyuva, Necati Kaplan, Ibrahim Yilmaz, Hanefi Ozbek, Duygu Yasar Sirin, Numan Karaaslan, Olcay Guler, Özkan Ateş
AIM: The aim of this in vitro experimental study was to design a novel, polyvinyl alcohol(PVA)-basedpolymericscaffold that permits the controlled release of insulin-likegrowthfactor1(IGF-1)/bonemorphogenetic protein-2(BMP-2) following intervertebral disc administration. MATERIAL AND METHODS: The drug delivery system was composed of two different solutions that formed a scaffold within seconds after coming into contact with each other. We performed swelling,pH,temperature tests and analysis of the controlled release of growth factors from this system...
April 9, 2018: Turkish Neurosurgery
Numan Karaarslan, Ibrahim Yilmaz, Hanefi Ozbek, Tezcan Caliskan, Savas Topuk, Duygu Yasar Sirin, Ozkan Ates
AIM: The aim of this study was to systematically investigate the role of artificial small interfering RNA (siRNA) molecules in glioblastoma treatment and to give a detailed overview of the literature concerning studies performed in this field worldwide in the last 31 years. MATERIAL AND METHODS: Articles about clinical trials conducted between December 1, 1949 and November 8, 2017, were identified from the Cochrane Collaboration, the Cochrane Library, Ovid MEDLINE, ProQuest, the National Library of Medicine, and PubMed electronic databases, using the terms "post transcriptional gene silencing," "small interfering RNA," "siRNA," and "glioblastoma," either individually or combined (\"OR\" and \"AND"), without language and country restrictions...
April 6, 2018: Turkish Neurosurgery
Gokhan Artas, Sait Ozturk, Tuncay Kuloglu, Adile Ferda Dagli, Murat Gonen, Hakan Artas, Suleyman Aydin, Fatih Serhat Erol
AIM: This study aimed to investigate the possible role of ELABELA (ELA) in the histopathological grading of gliomas. MATERIAL AND METHODS: We retrospectively assessed pathological specimens of patients who underwent surgery for intracranial space-occupying lesions. Only primary glioma specimens were included in this study. We enrolled 11 patients histologically diagnosed with low-grade glioma and 22 patients with high-grade glioma. The ELA antibody was applied to 4-6-µm-thick sections obtained from paraffin blocks...
April 6, 2018: Turkish Neurosurgery
Wan Yi, Shujun Xu, Xingang Li, Xiangyu Ma
AIM: This study aimed to study the protective effect of intraoperative awakening and central sulcus location on motor function for patients with gliomas located in motor areas. METHODS: A total of 68 patients with gliomas in motor areas were intubated with a laryngeal mask and rapidly underwent craniotomy without scalp clips and awakening, followed by localization of the central sulcus by somatosensory evoked potential. To protect brain function, we resected the greatest degree of tumor as possible and then finished the close-skull under an awakened state or general anesthesia...
April 6, 2018: Turkish Neurosurgery
Filip Vitosevic, Lukas Rasulic, Svetlana Milosevic Medenica
AIM: Study was performed to provide measurements of the posterior cerebral circulation using non-invasive imaging modality. MATERIAL AND METHODS: 120 patients aged from 12 to 76 years were analyzed using CT angiography. Measurements of vertebral arteries (VA), basilar artery, posterior cerebral arteries (PCA) and posterior communicating arteries were obtained. Basilar artery appearance and curvature was also noted. Differences between sides, genders and age groups were evaluated...
April 6, 2018: Turkish Neurosurgery
Zhong Yao, Chao You
Background Moymoya disease was a cerebrovascular condition, complicated by the recurrent stroke after surgery treatment. The accurate rate of good outcome and prognosis remained controversial. We aimed to summary and calculate the rate under the uniform definition of good outcome, evaluating the long-term effect of surgery. Methods Through systematically searching several databases, we included eligible studies measuring outcomes with the modified Rankin Scale (mRS), Glasgow Outcome Scale (GOS) and Kim's category...
April 6, 2018: Turkish Neurosurgery
Cengiz Tuncer, Canan Subasi, Cem Dinç, Erhan Turkoglu, Uygur Er
AIM: Postlaminectomy epidural fibrosis is a major source of decreased quality of life after spinal surgery. Prevention of epidural fibrosis seems a logical way for avoiding of some uneventful effects and reoperation. Many chemicals used for prevention of epidural fibrosis up to this day. The aim of this study is to assess efficacy of α-tocopherol as a topical antifibrotic agent on epidural fibrosis for lumbar laminectomy procedures. MATERIAL AND METHODS: Thirty-two adults rats assigned into 4 groups, with 8 rats in each group were used in this study...
March 19, 2018: Turkish Neurosurgery
Melih Bozkurt, Onur Ozgural, Gokmen Kahilogullari, Umit Eroglu, Ihsan Dogan, Haydar Sekmen, Nihat Egemen
AIM: We present our experience of 225 clipped aneurysms in 196 patients to compare indocyanine green video angiography (ICG-VA), micro-Doppler ultrasonography (MDUSG), and postoperative digital subtraction angiography (DSA) in terms of determining aneurysm obliteration, neck remnants, and parent artery patency. MATERIAL AND METHODS: This retrospective study included 196 patients (108 female and 88 male patients) treated between 2013 and 2016. In all cases, aneurysm neck remnants and vessel patency were assessed using ICG-VA and 16-Hz MDUSG...
March 19, 2018: Turkish Neurosurgery
Necati Ucler, Batu Hergunsel, Sait Oztruk, Serpil Kozan, Metin Kaplan
AIM: We aimed to evaluate postoperative clinical cure and recurrence rates in cases with ventrally localized spinal meningiomas that underwent Simpson grade 2 resection. MATERIAL AND METHODS: We evaluated eight cases (six females and two males; age, 28-86 years; mean age, 60 years) with ventrally localized spinal meningioma that underwent surgical treatment at our clinic. The tumors were localized in the thoracic region in seven cases and in the cervical region in one case...
March 19, 2018: Turkish Neurosurgery
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