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Turkish Neurosurgery

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https://www.readbyqxmd.com/read/28481393/differential-expression-of-micrornas-in-medulloblastoma-and-the-potential-functional-consequences
#1
Yuting Zhang, Lusheng Li, Ping Liang, Xuan Zhai, Yingliang Li, Yudong Zhou
AIM: To identify differentially expressed microRNAs in medulloblastoma, and to investigate their biological function. medulloblastomda farklı olarak ifade microRNA tespit etmek ve bunların biyolojik fonksiyonlarını araştırmak. MATERIAL AND METHODS: Differentially expressed microRNAs were identified using gene chips, and significantly different microRNAs were selected for verification using real time quantitative PCR. Potential target genes and their biological pathways were predicted by bioinformatics software...
April 12, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28481388/minimally-invasive-transforaminal-lumbar-interbody-fusion-with-percutaneous-bilateral-pedicle-screw-fixation-for-lumbosacral-spine-degenerative-diseases-a-retrospective-database-of-40-consecutive-treated-cases-and-literature-review
#2
Daniele Francesco Millimaggi, Valerio DI Norcia, Sabino Luzzi, Tommaso Alfiero, Renato Juan Galzio, Alessandro Ricci
AIM: To report our results about minimally invasive transforaminal lumbar interbody fusion (MI-TLIF) with bilateral pedicle screw fixation, in patients with degenerative lumbosacral spine disease. To describe the indications, surgical technique and results of a consecutive series of 40 patients undergone MI-TLIF. Despite the limited number of clinical studies, published data suggest tremendous potential advantages of this technique. MATERIAL AND METHODS: Forty patients with radiological findings of degenerative lumbosacral spine disease were undergone MI-TLIF between July 2012 and January 2015...
April 12, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28497436/factors-related-to-the-development-of-shunt-dependent-hydrocephalus-following-subarachnoid-hemorrhage-in-the-elderly
#3
Tae Seok Jeong, Chan Jong Yoo, Woo Kyung Kim, Gi Taek Yee, Eun Young Kim, Myeong Jin Kim
AIM: Surgical procedures for aneurysmal subarachnoid hemorrhage (SAH) are increasing among the elderly as the population ages. Chronic shunt-dependent hydrocephalus is a recognized complication of SAH. The purpose of this study was to identify factors predictive of the development of shunt-dependent hydrocephalus among elderly patients with SAH. MATERIAL AND METHODS: We retrospectively studied 878 patients, including 275 patients ≥ 65 years old, with SAH treated between 2005 and 2015 to identify factors contributing to the development of shunt-dependent hydrocephalus...
April 4, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28497435/genetic-dimension-of-intervertebral-disc-degeneration-polymorphism-of-matrix-metalloproteinase-1-and-3-in-the-north-iranian-population
#4
Alia Saberi, Zivar Salehi, Bahram Naderinabi, Sahar Hojaat Ansari, Sohail Mashayekhi
AIM: Exploring the relationship between two polymorphisms (MMP-1-755 T/G [rs498186] and MMP-3 A/C [rs632478]) and disc degeneration. MATERIAL AND METHODS: We performed a case-control study on 130 cases with intervertebral disc degeneration confirmed by Magnetic Resonance Imaging (MRI) and 210 healthy individuals. Schneiderman criterion was used to determine the severity of the disc degeneration. Blood samples were collected from the participants. The genotyping was performed by polymerase chain reaction - restriction fragment length polymorphism (PCR-RFLP) method...
April 4, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28481389/comparison-of-the-effects-of-curcumin-tramadol-and-surgical-treatments-on-neuropathic-pain-induced-by-chronic-constriction-injury-in-rat
#5
Dilek Ceyhan, Atacan Emre Kocman, Engin Yildirim, Orhan Ozatik, Sule Aydin, Kose Aydan
AIM: Nerve entrapment syndromes are the most common causes of neuropathic pain. Surgical decompression is preferred method of treatment. The goal of the study was to compare the efficacy of curcumin, tramadol and chronic constriction release treatment (CCR), individually or together, in a rat model of sciatic nerve injury. MATERIAL AND METHODS: Eighty male-rats were divided into eight study groups. Group 1 was the sham group. Group 2 was the control group with established chronic constriction injury (CCI)...
April 4, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28481390/multimodal-intraoperative-neurophysiologic-monitoring-in-the-neurosurgical-oncology
#6
Sema Brandmeier, Emine Taşkiran, Fatihhan Bölükbaşi, Ramazan Sari, İlhan Elmaci
AIM: Neurosurgical oncology that is performed for lesions located in critical areas like the sensorimotor area has additional risk because it may cause serious neurological deficiencies. Some intraoperative neuromonitoring (IONM) modalities can effectively help the surgeons to maximize resections of this kind of lesions with or without an acceptable neurological deficiency. Our aim was to share our IONM experiences with patients who underwent intracranial lesion surgery in critical areas between September 2013 and January 2015...
March 26, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28481397/endoscopic-endonasal-cerebrospinal-fluid-leak-repair-on-the-ventral-midline-skull-base-a-single-neurosurgical-center-experience
#7
Cihan Isler, Merdin Lyutviev Ahmedov, Mehmet Yigit Akgun, Baris Kucukyuruk, Nurperi Gazioglu, Galip Sanus, Necmettin Tanriover
AIM: The aim of this study was to present the results of endoscopic endonasal repair of ventral midline skull base cerebrospinal fluid (CSF) leak (VMSBL) at our institution and to discuss the technique and results from a neurosurgical perspective. MATERIAL AND METHODS: A retrospective analysis of all VMSBL cases that underwent endoscopic endonasal skull base approach (EESBA) for CSF leak repair at a single tertiary neurosurgical center was performed. Twenty six patients with an average age of 44...
March 25, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28481396/active-rebleeding-from-a-ruptured-middle-cerebral-artery-aneurysm-during-diagnostic-catheter-angiography
#8
Pinar Celtikci, Onder Eraslan, Onur Ergun, Esra Soyer Guldogan, Mehmet Erhan Turkoglu
Rebleeding of cerebral aneurysms was reported during diagnostic angiography previously. However, capturing the exact moment of active rebleeding of a cerebral aneurysm during angiography is extremely rare. Here, a case of a rebleeding middle cerebral artery aneurysm during diagnostic digital subtraction angiography was illustrated, accompanied with a video demonstration of the incident which is the only one in the literature. During the acquisition of lateral projection digital subtraction angiography images, active extravasation of the contrast medium was witnessed indicating rebleeding...
March 25, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28481395/a-systematic-review-on-machine-learning-in-neurosurgery-the-future-of-decision-making-in-patient-care
#9
Emrah Celtikci
The current practice of neurosurgery depends on clinical practice guidelines and evidence-based research publications that derive results using statistical methods. However, statistical analysis methods have some limitations like; inability to analyze non-linear variables, requiring setting of a level of significance, being impractical for analyzing large amounts of data and possibility of human bias. Machine learning is an emerging method for analyzing massive amounts of complex data which relies on algorithms that allow computers to learn and make accurate predictions...
March 25, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28481394/the-effect-of-intravenous-l-carnitine-on-vasospasm-process-in-the-experimental-subarachnoid-hemorrhage-model
#10
Ahmet Soyer, Murat Gokten, Kamil Oge, Figen Soylemezoglu
AIM: Cerebral vasospasm after subarachnoid hemorrhage (SAH) is an important cause of morbidity and mortality. In this study we examined the effects of L-carnitine on cerebral vasospasm process. MATERIAL AND METHODS: Twenty male New Zealand white rabbits were randomly divided into 4 groups. Group 1 served as control; group 2 were not subjected to SAH and received intravenous L-carnitine 3 times; group 3 were subjected to SAH and group 4 were subjected to SAH and treated with 100 mg/kg intravenous L-carnitine at 0 24 and 48 hours after SAH...
March 25, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28481392/customised-cranioplasty-implant-for-decompressive-craniectomy-patients-a-technical-note
#11
Kaif Mohammad
Cranioplasty is a commonly performed procedure following decompressive craniectomy. The patients are usually young earning persons and increasing cost of treatment is difficult to bear especially in low and middle income countries. A variety of options are available for cranioplasty ranging from autologus bone graft to xenograft and synthetic materials. Presently the autologous cryopreserved or subcutaneously preserved bone graft is considered as preferred choice but is has its drawback of bone resorption and infection ...
March 25, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28481391/novel-hybrid-operating-table-for-neuroendovascular-treatment
#12
Park Jong-Hyun, Mun Jonghyeon, Shin Dong-Seung, Kim Bum-Tae
BACKGROUND: The integration of interventional and surgical techniques is requiring the development of a new working environment equipped for the needs of an interdisciplinary neurovascular team. However, conventional surgical and interventional tables have only a limited ability to provide for these needs. We have developed a concept mobile hybrid operating table that provides the ability for such a team to conduct both endovascular and surgical procedures in a single session. METHODS: We developed methods that provide surgeons with angiography-guided surgery techniques for use in a conventional operating room environment...
March 25, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28383092/effects-of-arginine-vasopressin-and-v1-receptor-antagonist-on-cerebral-vasospasm-secondary-to-subarachnoid-hemorrhage-an-experimental-study
#13
Derviş Mansuri Yilmaz, Ersin Haciyakupoğlu, Serkan Diril, Leman Sencar, Erol Akgül, Sait Polat, Sebahattin Haciyakupoğlu, Ersin Nazlican
AIM: The aim of this study is to examine morphological, radiological and biochemical effects of arginine vasopressin(AV) and AV V1 receptor antagonist cerebral vasospasm(CVS) in rabbit subarachnoid hemorrhage(SAH). MATERIAL AND METHODS: Forty male New Zealand white rabbits were randomly divided to four groups comprising 10 rabbits each. The groups were 1) control, 2) subarachnoid hemorrhage(SAH), 3) SAH+AV application, 4) SAH+V1 antagonist of AV V1 receptor Diameters of the basilar artery of all the groups were measured on angiograms...
March 9, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28383091/a-new-technique-for-the-surgical-treatment-of-atlantoaxial-instability-c1-lateral-mass-and-c2-3-transfacet-screwing
#14
Salim Senturk, Goktug Akyoldas, Onur Yaman, Ali Fahir Ozer
AIM: Atlantoaxial instability is a special entity that may be caused by many disorders such as trauma, tumor, arthritis, congenital malformation and infection. Atlantoaxial fixation is needed to provide stability, prevent neurological deficits and correct deformity. The objective of this study is to introduce an alternative technique for the treatment of atlantoaxial instability in patients who have vertebral artery anomaly, anomalous C2 or osteoporosis. MATERIAL AND METHODS: C1-2-3 fixation was performed in a 50-years-old, male patient with atlantoaxial instability due to os odontoideum...
March 9, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28383090/lumbosacral-epidural-primitive-neuroectodermal-tumor-pnet-case-report-and-literature-review
#15
Keyvan Eghbal, Amir Reza Dehghanian, Fariborz Ghaffarpasand
BACKGROUND: The primitive neuroectodermal tumors (PNET) of the spine are rare and usually are intramedullary and being reported in children. We herein report an epidural PNET of lumbosacral area presenting with cauda equine syndrome in an adult. CASE REPORT: A 38-year-old woman presented to our emergency room with acute onset lower extremity weakness and urinary incontinency. Emergency MRI revealed an isoitense on T1-weighted and heterogeneously hyperintense in T2-weighted images in epidural lumbosacral area...
March 9, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28346633/one-stage-posterior-approach-in-the-treatment-of-consecutive-multi-segment-thoracic-tuberculosis-with-kyphosis
#16
Zhong Nanzhe, Kong Jinhai, Sun Zhengwang, Qian Ming, Liu Tielong, Xiao Jianru
AIM: This study is to evaluate the clinical efficacy of one-stage posterior approach in treating consecutive multiple-segment thoracic tuberculosis with kyphosis. MATERIAL AND METHODS: A retrospective study was performed. The data of 22 patients with consecutive multi-level thoracic tuberculosis who underwent one-stage posterior approach of debridement, bone grafting, and drainage with pedicle screws fixation were collected. The kyphotic angle was 61.6°±3.1° pre-operatively...
February 27, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28345126/open-door-laminoplasty-with-preservation-of-muscle-attachments-of-c2-and-c7-for-cervical-spondylotic-myelopathy-retrospective-study
#17
Halil Ibrahim Secer, Ferhat Harman, Murat Hamit Aytar, Serdar Kahraman
AIM: Some restriction and complications, such as progression of kyphosis, incidence of axial neck pain and decrease of postoperative cervical range of motion are concern. We designed this retrospective clinical study to evaluate the effect of laminoplasty by preserving the muscle attachments of C2 and C7 spinous processes on ROM, axial neck pain and cervical lordosis. MATERIAL AND METHODS: 27 cases with cervical spondylotic myelopathy underwent open-door laminoplasty with the protection of the muscles attachment to the C2 and C7 spinous process and laminae between 2007 and 2013...
February 27, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28345123/traumatic-pseudoaneurysms-of-the-head-in-war-time-report-of-two-unusual-cases
#18
Tayfun Hakan, Ahmet Cemil Kaur
Either intracranial or extracranial pseudoaneurysms due to penetrating head injuries with gunshot are very rare entities. As the pseudoaneurysms of the superficial temporal artery are represented commonly with a pulsating mass lesion beneath scalp, the intracranial pseudoaneurysms are represented with symptoms including decreased conscious level, seizure, or focal neurological deficits. Here, two patients with combat related pseudoaneurysms are reported; one was in distal cortical branch of anterior cerebral artery and one was in superficial temporal artery...
February 27, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28345125/new-clues-in-the-malignant-progression-of-glioblastoma-can-the-thioredoxin-system-play-a-role
#19
Fatih Erdi, Bulent Kaya, Hasan Esen, Yasar Karatas, Sıddıka Findik, Fatih Keskin, Bahadır Feyzioglu, Erdal Kalkan
AIM: The main aim of this study is to evaluate and compare the expression of thioredoxin reductase 1 (TrxR1) in primary and secondary glioblastoma samples. MATERIAL AND METHODS: Surgically resected human glioblastoma samples from 40 patients who underwent surgery at our institute were extracted from their histopathological specimens and divided into three groups. Ten histopathologically regular cerebral tissue, which acquired from the non-neoplastic portion of the specimens were assigned as the control group...
February 21, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28345124/evaluation-of-cortical-brain-parenchyma-by-diffusion-and-perfusion-mri-before-and-after-chronic-subdural-hematoma-surgery
#20
Bekir Akgun, Hakan Cakin, Sait Ozturk, Hanefi Yildirim, Izzet Okcesiz, Saim Kazan, Fatih Serhat Erol
AIM: To evaluate microcirculatory changes in neighboring parenchyma as a result of pressure due to chronic subdural hematoma (CSDH) in early and late periods after hematoma drainage. MATERIAL AND METHODS: The subjects comprised 25 patients who underwent CSDH drainage. Brain diffusion and perfusion MRIs were obtained preoperatively, 48 h (early period) and 2 months (late period) postoperatively. Measurements were performed on 1 cm2 regions of interest in the neighboring parenchymal tissue...
February 21, 2017: Turkish Neurosurgery
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