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Turkish Neurosurgery

Kagan Tun, Berker Cemil, Emre Cemal Gokce
AIM: In unique clinical situations where C1-C2 posterior fixation is not available or has previously failed, an anterior transarticular screw (ATAS) may be a viable alternative. However, there aren't previous reports that investigate possible screw angles, screw entry points, and screw length based on computerized tomography multiplanar reconstruction images in Turkish patients. To determine the morphometric characteristics C1-C2 vertebrae to perform anterior transarticular crossing screw fixation...
November 21, 2016: Turkish Neurosurgery
Hai-Tao Li, Hua-Jun Zhou, Jian-Hua Zhong, Tao Tang, Han-Jin Cui, Qi-Mei Zhang, Jing-Hua Zhou, Qiang Zhang
AIM: Angiogenesis occurs after intracerebral hemorrhage (ICH). Hypoxia-inducible factor-1α (HIF-1α) is a critical regulator of angiogenesis; however, its role in the central nervous system remains controversial. 2-Methoxyestradiol (2ME2), a natural metabolite of estrogen, is known to inhibit HIF-1α. In the present study, we investigated the effect of 2ME2 in a rat model of ICH-induced angiogenesis. MATERIAL AND METHODS: Sprague-Dawley male rats were randomly divided into 5 groups: Sham operated group; ICH; ICH+2ME2; and ICH+Vehicle groups...
November 21, 2016: Turkish Neurosurgery
Zahra Abdi, Hossien Eskandary, Seyed Noureddin Nematollahi-Mahani
AIM: Glioblastoma multiforme (GBM) is one of the malignant brain tumors, which occurs most frequently. Despite advances in therapy techniques, is the cure of GBM a major concern. Accordingly, there is a lot of interest in devising novel approaches, such as stem cell therapy, to treat patients with GBM. The aim of this study is to investigate the effects of human bone marrow stem cells (BMSCs) as well as human olfactory ensheathing cells (OECs) on outgrowth of U87 glioma in rats. MATERIAL AND METHODS: OECs and BMS cells were obtained from the volunteers...
November 21, 2016: Turkish Neurosurgery
Mehmet Onur Yüksel, Mehmet Sabri Gürbüz, Merih Iş, Hakan Somay
AIM: The aim of this study was to determine whether Thoracolumbar Injury Classification and Severity Score (TLICS) and AOSpine Thoracolumbar Injury Classification System have any superiority to each other regarding the reliability of their recommendations in the surgical management of unstable thoracolumbar burst fractures. MATERIAL AND METHODS: Fifty-five consecutive patients with thoracolumbar burst fractures undergoing instrumentation between 2010 and 2015 were analyzed retrospectively...
November 18, 2016: Turkish Neurosurgery
Sait Naderi, Gülten Dinç
Spine deformities are among the most important spinal disorders, affecting health related life quality. Although, there are some studies in past centuries, most of spine deformity related studies and researches started in last century. Many surgical techniques, performed between 1960 and 1990, made scoliosis a touchable pathology. These techniques started with Harrington\'s system, wiring techniques, pedicle screw techniques, and all other universal techniques. Anterior and 360 degree techniques contributed to this process...
November 15, 2016: Turkish Neurosurgery
Liu Peng, Nie Hai
AIM: TThe purpose of this study was to compare and analyze the influence of the duration of neurological symptoms and degree of neurological deficits on the postoperative neurological recovery of patients with neurological deficits caused by spinal tuberculosis (TB). MATERIAL AND METHODS: We retrospectively reviewed 47 adult patients with neurological deficits caused by spinal TB. They were divided into three and four groups according to the duration of neurological symptoms and degree of neurological deficits, respectively...
November 11, 2016: Turkish Neurosurgery
Yad Ram Yadav, Jitin Bajaj, Vijay Parihar, Shailendra Ratre, Anurag Pateriya
: Although endoscopic techniques have many advantages including improved visualizations and magnification., these are also associated with limitations. Objective of this study is to discuss practical aspects that can reduce complications after endoscopic procedures, and their management. Review is based on personal experience of more than 2000 neuroendoscopic procedures performed by the senior author. Topic search was made on PubMed using Neuroendoscopy, complications and neuroendoscopy, complication avoidance and neuroendoscopy, endoscopic neurosurgery, and minimally invasive neurosurgery...
November 11, 2016: Turkish Neurosurgery
Mahmut Özden, Salim Katar, Hakan Hanimoğlu, Mustafa Onur Ulu, Cihan Işler, Oğuz Baran, Veysel Antar, Cumhur Gökhan Ekmekci, Mehmet Yaşar Kaynar
AIM: Evidences suggest an association between MMP-9 functional gene polymorphisms with several tumors. The aim of this study was to investigate the possible role of single-nucleotide polymorphisms (SNP) at MMP-9 R279Q A/G, P574R G/C and R668Q G/A and R668Q (rs17577) genotypes with glial tumors in Turkey. MATERIAL AND METHODS: The present series consisted of tissue samples obtained from 100 cancer-free controls and 100 patients who had undergone glial tumor resection from 2007 to 2011 at the Cerrahpasa Medical Faculty of Istanbul University...
November 11, 2016: Turkish Neurosurgery
Sukru Aykol, Fikret Dogulu, Memduh Kaymaz, Gokhan Kurt, Hakan Emmez, Alp Ozgun Borcek
No abstract text is available yet for this article.
2017: Turkish Neurosurgery
Tayfun Hakan, Erhan Celikoglu, Fugen Aker, Nagehan Barisik
No abstract text is available yet for this article.
2017: Turkish Neurosurgery
Murat Sakir Eksi, Sumeyye Coruh Kaplan, Baran Yilmaz, Akin Akakin, Zafer Orkun Toktas, Deniz Konya, Turker Kilic
AIM: National and international society meetings are suitable mediums at which diverse research topics from basic, clinical and translational sciences can be presented to an audience of peers. In this study, our purpose was to evaluate publication rates of presentations in the last recent four years" annual scientific meetings of Turkish Neurosurgical Society (TNS). MATERIAL AND METHODS: Abstracts of both podium and poster presentations were retrieved from the congress booklets of TNS...
2017: Turkish Neurosurgery
Ki-Su Park, Chang-Heon Lee, Seong-Hyun Park, Sung-Kyoo Hwang, Jeong-Hyun Hwang
AIM: The purpose of this study was to investigate whether the intensity of trauma influences the pathogenesis of traumatic chronic subdural hematoma (CSDH). MATERIAL AND METHODS: Thirty-one patients treated surgically for traumatic CSDH were divided into high-impact and lowimpact groups according to the intensity of trauma. They were respectively evaluated with respect to clinical and radiological findings at presentation, and the subdural concentrations of interleukin-6 (IL-6), interleukin-8 (IL-8), vascular endothelial growth factor (VEGF), basic fibroblast growth factor, and beta-trace protein (ΒTP) [a highly specific protein in the cerebrospinal fluid (CSF)] related to the pathogenesis of CSDH...
2017: Turkish Neurosurgery
Ahmet Kucuk, Abdulfettah Tumturk, Ismail Samil Gergin, Sukru Oral, Sureyya Burcu Gorkem, Ali Kurtsoy, Halit Madenoglu, Ibrahim Suat Oktem
AIM: Barrel stave osteotomy is a widely used procedure in neurosurgery for the majority of craniosynostosis patients. Both in the intraoperative and postoperative periods, there is inevitable leakage type bleeding from the bones undergoing osteotomy. A number of studies have been performed in order to prevent this complication but a concise procedure is still lacking. MATERIAL AND METHODS: Synostectomy and parietotemporal barrel stave osteotomy were applied to 143 patients who were operated on with a diagnosis of craniosynostosis between the years 2005-2013...
2017: Turkish Neurosurgery
Fatih Aydemir, Kadir Tufan, Melih Cekinmez, Ozgur Kardes, Feyzi Birol Sarica, Erkan Topkan, Erkin Sonmez, Ozlem Alkan, Gamze Ugurluer, Nur Altinors
AIM: In this study, factors affecting survival, local failure, distant brain failure, whole brain failure and whole-brain radiation therapy (WBRT) free survival according to histological subtypes were investigated in patients with brain metastases from non-small cell lung cancer (NSCLC). MATERIAL AND METHODS: Patients with positive pathology reports for adenocarcinoma (ACA) and squamous cell carcinoma (SCC) were included in the study. Seventy-eight ACA and 26 SCC patients were included in the study...
2017: Turkish Neurosurgery
Ali Yilmaz, Mete Karatay, Timur Yildirim, Haydar Celik, Idris Sertbas, Yavuz Erdem, Muzaffer Caydere, Hasan Serdar Isik, Mehmet Akif Bayar
AIM: One of the most significant reasons for persistent low back pain experienced after spinal surgery is epidural fibrosis seen after laminectomy procedures. This study shows the effects of Ranibizumab on spinal epidural fibrosis in the laminectomy area by blocking the effect of vascular endothelial growth factor. MATERIAL AND METHODS: Twenty Wistar rats were used in this study. Rats were divided into two groups; a control group and a ranibizumab group. Only laminectomy was performed to the control group...
2017: Turkish Neurosurgery
Halit Diri, Ersin Ozaslan, Ali Kurtsoy, Bulent Tucer, Yasin Simsek, Figen Ozturk, Ahmet Candan Durak, Sirac Erten, Fahri Bayram
AIM: The aim of this study was to assess the relationships among immunohistochemical staining patterns and prognostic factors in patients with non-functioning pituitary adenoma (NFPA). MATERIAL AND METHODS: The study included 103 patients who had undergone pituitary surgery for NFPAs. The prognostic factors evaluated were initial tumor size, cavernous sinus invasion, compression of the optic chiasm, recurrence, residual tissue, reoperation, and hypopituitarism. RESULTS: Recurrence rates were higher for NFPAs with large initial tumor volume and preoperative cavernous sinus invasion...
2017: Turkish Neurosurgery
Mehmet Tokmak, Muserref Hilal Sehitoglu, Yasemin Yuksel, Mustafa Guven, Tarik Akman, Adem Bozkurt Aras, Umut Yaka, Cengiz Gomleksiz, Serdar Baki Albayrak, Murat Cosar
AIM: In the relevant literature, there is no experimental study that investigated the axon protective effects of syringic acid- a polyphenol compound- with an anti-oxidant capacity on ischemia/reperfusion injury. MATERIAL AND METHODS: The rats were randomly divided into four groups: Control group (no medication or surgical procedure), Sham group, Syringic acid group, and Methyprednisolone (MP) Group. Ischemia was achieved by abdominal aorta clamping and all animals were sacrificed 24 hours after ischemia...
2017: Turkish Neurosurgery
Mustafa Karademir, Ahmet Kucuk, Halil Ulutabanca, Ahmet Selcuklu, Ahmet Menku, Bulent Tucer
AIM: To compare cervical hemilaminectomy with cervical laminoplasty to determine the prognostic significance of both methods in cervical spondylotic myelopathy (CSM). This study is first in the literature to compare the hemilaminectomy and laminoplasty procedures MATERIAL and METHODS: A total of 42 patients who underwent surgery due to CSM and followed for at least 24 months were included in the study. Thirty-four out of 42 patients were males, while 8 were females; the mean age of the patients was 63...
2017: Turkish Neurosurgery
Ahmet Bekar, M Ozgur Taskapilioğlu, Pinar Eser, Hulya Bilgin
AIM: To evaluate the safety and effectiveness of computed tomography-guided high-level percutaneous selective cervical cordotomy (CT-guided HPSCC). MATERIAL AND METHODS: CT-guided percutaneous procedures were performed in fifty-nine patients between the years 2004- 2013 for cancer pain. Forty-eight patients with cancer-related body pain were treated with CT-guided HPSCC was evaluated retrospectively. RESULTS: CT-guided HPSCC was performed in 33 male and 15 female patients...
2017: Turkish Neurosurgery
Ke Wang, Dongjiang Chen, Xiangyuan Cao, Liang Gao
AIM: This study aims to compare clinical outcomes in patients with chronic subdural hematoma (CSDH) following twist drill craniostomy (TDC) or burr hole craniostomy (BHC). MATERIAL AND METHODS: A prospective cohort study was conducted in the patients who suffered from symptomatic CSDH and received surgical treatment in our department from Jan 2011 to Dec 2013. Each patient was followed 3 months after the surgery. RESULTS: Thirty-eight and 45 patients received TDC and BHC treatment, respectively...
2017: Turkish Neurosurgery
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