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Turkish Neurosurgery

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https://www.readbyqxmd.com/read/29292492/feasibility-of-interlaminar-lumbar-discectomy-through-percutaneous-transforaminal-endoscopy-and-blunt-perforation-of-the-ligamentum-flavum
#1
Baoshan Hu, Gang Rui, Naikun Sun, Jinyi Feng, Shengrong Lin
AIM: To determine the efficacy, safety, and clinical value of a novel surgical procedure involving the blunt perforation of the ligamentum flavum (LF) during endoscopic interlaminar lumbar discectomy. MATERIAL AND METHODS: This was a prospective study of 50 patients (27 males, 17-51 years of age) undergoing lumbar discectomy for single segment L4/L5 or L5/S1 disk herniation were grouped into the control (cutting of the LF; n=28) and test (blunt perforation; n=22) groups...
July 11, 2018: Turkish Neurosurgery
https://www.readbyqxmd.com/read/29204982/assessment-of-the-mri-and-behavioral-test-results-in-focal-cerebral-ischemia-reperfusion-model-in-rat-after-separate-and-combined-use-of-mouse-derived-neural-progenitor-cells-human-derived-neural-progenitor-cells-and-atorvastatin
#2
Alican Tahta, Nail Izgi, Tugba Bagci Onder, Ece Erdag, Yavuz Aras, Cetin Genc
AIM: We aimed to assess the efficacy of Neural progenitor cell (NPC) transplantation in ischemic stroke, and to investigate whether atorvastatin enhances therapeutic potency of NPC after stroke. MATERIAL AND METHODS: Focal cerebral ischemia-reperfusion model was performed by transient occlusion of middle cerebral artery. Rats were assigned randomly to receive intracerebral transplantation of mouse NPC alone (mNPC), human NPC alone (hNPC), mouse NPC plus oral atorvastatin (mNPC+A), human NPC plus oral atorvastatin (hNPC+A), oral atorvastatin alone, or intracerebral Dulbecco's Modified Eagle's medium injection (control group)...
November 1, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/29204981/neuroprotective-effects-of-oleocanthal-a-compound-in-virgin-olive-oil-in-a-rat-model-of-traumatic-brain-injury
#3
Mesut Mete, Isıl Aydemir, Ulkun Unlu Unsal, Fatih Collu, Gokhan Vatandas, Beyhan Gurcu, Yusuf Kurtulus Duransoy, Fatma Taneli, Mehmet Ibrahim Tugrul, Mehmet Selcuki
AIM: TBI has two distinct phases: primary and secondary injury. Many agents have been used to prevent secondary injury. Oleocanthal (OC) has anti-inflammatory and antioxidant properties similar nonsteroidal anti-inflammatory drug. We evaluated the neuroprotective effects of OC in a rat model of TBI. MATERIAL AND METHODS: Twenty-six adult male, Wistar albino rats were used. The rats were divided into 4 groups. group 1, sham (n = 5). group 2, trauma (n = 5): Rats were treated with 10 mg/kg saline intraperitoneally (IP) twice a day...
November 1, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/29204980/usefulness-and-radiological-evaluation-of-accuracy-of-innovative-smart-hand-technique-for-pedicle-screw-placement-an-anatomical-study
#4
Ayhan Comert, İhsan Dogan, Y Sukru Çaglar
AIM: The aim of this study is to use a smartphone application during pedicle screw placement navigation and examine the accuracy of this application on anatomical dry vertebrae model. MATERIAL AND METHODS: 76 dry vertebrae were used for this study and pedicle entry points, projections of pedicle screw trajectory lines in lateral and superior aspect of vertebral body were identified and drawn for each vertebra bilaterally. In each position, all angulations were measured directly before the procedure manually...
November 1, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/29204979/treatment-of-spontaneous-subarachnoid-hemorrhage-and-self-reported-neuropsychological-performance-at-6-months-results-of-a-prospective-clinical-pilot-study-on-good-grade-patients
#5
Elisabeth Bründl, Petra Schödel, Sylvia Bele, Martin Proescholdt, Judith Scheitzach, Florian Zeman, Alexander Brawanski, Karl-Michael Schebesch
AIM: Limited focus has been placed on neuropsychological patient profiles after spontaneous subarachnoid hemorrhage (sSAH). We conducted a prospective controlled study in good-grade sSAH patients to evaluate the time course of treatment-specific differences in cognitive processing after sSAH. MATERIAL AND METHODS: 26 consecutive sSAH patients were enrolled (drop out n=5). 9 patients received endovascular aneurysm occlusion (EV), 6 patients were treated microsurgically (MS), and 6 patients with perimesencephalic SAH (pSAH) underwent standardized intensive medical care...
November 1, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/29165750/our-experience-in-the-management-of-csf-otorrhea-a-transmastoid-approach-with-middle-ear-cavity-obliteration-and-a-middle-cranial-fossa-approach
#6
Asli Cakir Cetin, Nuri Karabay, Enis Alpin Guneri
In this report, we present two cases of patients with cerebrospinal fluid (CSF) otorrhea who underwent surgical repair through either a transmastoid or middle cranial fossa approach. In our first case, a 34-year-old male after head trauma with conductive hearing loss and a House-Brackmann grade 2 facial palsy was found to have a soft tissue mass protruding through his right tympanic membrane. Radiological examination revealed a wide tegmen tympani defect. He underwent surgery via a transmastoid approach with repair of the defect and blind sac closure of the external auditory canal after middle ear cavity obliteration...
November 1, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/29165749/analysis-of-the-factors-affecting-surgical-site-infection-and-bone-flap-resorption-after-cranioplasty-with-autologous-cryopreserved-bone-the-importance-of-temporalis-muscle-preservation
#7
Sung-Won Jin, Sang-Dae Kim, Sung-Kon Ha, Dong-Jun Lim, Hwa Lee, Hi-Jin You
AIM: A decompressive craniectomy is a potentially life-saving surgical procedure for raised intracranial pressure. Once it has been performed, patients are obliged to undergo a second procedure with cranioplasty. The aim of this study was to investigate the outcomes and associated complications after delayed cranioplasty using autologous, cryopreserved bone. MATERIAL AND METHODS: This retrospective study included 57 consecutive patients treated with cranioplasty with autologous cryopreserved bone for various conditions causing increased intracranial pressure due to brain swelling...
November 1, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/29165746/computed-tomographic-localization-of-the-central-sulcus-a-morphometric-study-in-adult-patients
#8
Dan Zimelewicz Oberman, Jorge Rasmussen, Maximiliano Toscano, Ezequiel Goldschmidt, Pablo Ajler
AIM: Despite advances in intraoperative navigation and electrocorticography, neuroanatomical knowledge is an essential tool for neurosurgical planning. The aim of this study was to accurately describe the relations between the anatomical landmarks of the cranial convexity and the main cortical structures. MATERIAL AND METHODS: A retrospective cross-sectional, observational study was performed. Computed tomography scans of 71 adult patients with no pathological imaging were analyzed...
November 1, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/29165745/supratentorial-embryonal-tumors-in-elderly-diagnostic-pitfalls-and-clinical-prognosis
#9
Pierluigi Granaroli, Federica Novegno, Tommaso Lunardi, Pierpaolo Lunardi
Supratentorial embryonal tumours are very rare malignant tumours of neuroectodermal origin, characterized by an aggressive clinical behavior. They occur prevalently in children. They have been sporadically described in adults and represent an even rarer occurrence in elderly patients, raising many issues on the diagnostic pitfalls and their appropriate management. We present an unusual case of embryonal tumor in a 62-year-old man who presented with speech disorder, left IIIrd and Vth cranial nerves partial deficit secondary to a left temporo-insular embryonal tumour: clinico-radiological features, histopathological insights, therapeutic options and results are discussed along with a review of the most relevant literature, addressing the specific issue of differential diagnosis and the expected results in the elderly population...
November 1, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/29165744/hypothermia-therapy-after-traumatic-brain-injury-a-systematic-review-and-meta-analysis
#10
Lige Leng
The purpose of this article was mainly focus on in patients with TBI, does or not hypothermia improved mortality and/or chance of good neurologic outcome compared with standard of care alone. We performed a comprehensive search strategy. Articles were eliminated in a stepwise fashion. Data from each study was entered in Review Manager (RevMan) software version 5.0 when reported. 7 studies, including 1331 patients confirmed to all selection criteria and were identified. This meta-analysis got all data of 7 articles together to come to a conclusion, besides that, it also carried on a detailed analysis of different classification, trying to outline the possible mechanism...
October 29, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/29131236/chronic-subdural-hematoma-associated-with-arachnoid-cyst-of-the-middle-fossa-surgical-treatment-and-mid-term-results-in-fifteen-patients
#11
Ahmet Murat Müslüman, Barış Özöner, Atilla Kirçelli, Songül Meltem Can, Adem Yilmaz, Ayça Kaldirimoğlu, Balkan Şahin
AIM: We report the neurological and radiological features, surgical management and Mid-term outcome in a series of patients with chronic subdural hematoma (CSDH) and associated ipsilateral arachnoid cyst (AC) of the middle fossa. MATERIAL AND METHODS: Between August 2004 and August 2012, 453 patients were treated with diagnosis of CSDH in our clinic. Of those, 15 patients had ipsilateral arachnoid cyst in the middle fossa. A single burr hole craniostomy was performed to drain the hematoma and the AC left intact at first in 14 patients, one patient had no surgical intervention...
October 18, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/29131235/anatomical-variations-of-brachial-plexus-in-fetal-cadavers
#12
Alparslan Kirik, Senem Ertuğrul Mut, Mehmet Kadri Daneyemez, Halil İbrahim Seçer
AIM: The plexus brachialis is a complex structure with anatomical variations and connections with neighboring tissues. These variations may cause disparity in the motor and sensorial innervations of the upper extremity. The knowledge of anatomy and probable variations are important for performing surgical procedures in the neck, shoulder and axilla. This study was planned to demonstrate the anatomical variations of infantile brachial plexus. MATERIAL AND METHODS: A total of 20 plexus brachialis from 11 fetal cadavers were dissected and examined microscopically...
October 18, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/29131234/the-role-of-triangular-vertebral-canal-shape-in-surgical-management-of-patients-with-lumbar-spinal-stenosis-a-cross-sectional-study
#13
Huseyin Bozkurt, İsmail Kaya, Bilge Oztoprak
AIM: We assessed the role of triangular vertebral canal shape (VCS) in pain severity, pain-related findings, and postoperative satisfaction in patients with lumbar spinal stenosis (LSS) who had undergone decompressive surgery. MATERIAL AND METHODS: This cross-sectional study conducted at a single center included 61 consecutive patients who had undergone surgical treatment for LSS. By comparing pre- and postoperative data, the role of triangular VCS in pain severity [assessed using a visual analog scale (VAS)], pain-related findings, and postoperative satisfaction of patients was examined...
October 18, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/29131233/comparison-of-tof-mra-contrast-enhanced-mra-and-subtracted-cta-from-ctp-in-residue-evaluation-of-treated-intracranial-aneurysms
#14
Tolga Turan Dündar, Ayşe Aralaşmak, Hüseyin Özdemir, Mehmet Hakan Seyithanoğlu, Ömer Uysal, Hüseyin Toprak, Serkan Kitiş, Erdinç Özek, Alpay Alkan
AIM: To compare effectiveness of contrast-enhanced MRA (CE-MRA), 3D-Time-of-flight MRA (3D-TOF-MRA) and subtracted CTA from CTP (sub-CTA) in residue evaluation of intracranial aneurysms treated either with coiling or clipping. MATERIAL AND METHODS: Sixteen treated aneurysms, which were evaluated with three methods within two weeks after the operation, were enrolled. The success of each imaging techniques in demonstration of residue aneurysm and nearby vessels was compared by Fisher\'s Exact Test...
October 18, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/29165748/orbital-arteriovenous-fistula-around-the-optic-nerve-treated-by-transvenous-embolization
#15
Masayuki Sato, Yuji Matsumaru, Tatsuo Amano, Yuki Kamiya
(Background) Intraorbital arteriovenous fistula is a very rare disease, therefore an optimal treatment strategy has not yet been established. Here we describe the use of high-resolution cone-beam CT (CBCT) and selective angiography to visualize the detailed anatomy of orbital vessels. The information provided by the intra-operative imaging led to a change in treatment strategy and eventually to successful transvenous coil embolization. (Clinical presentation) A 55-year-old man presented with right exophthalmos, chemosis and diplopia 4 months previously...
October 11, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/29165747/the-effect-of-rosmarinus-officinalis-and-chemotherapeutic-etoposide-on-glioblastoma-u87-mg-cell-culture
#16
Meryem Damla Özdemir, Dilek Göktürk
AIM: Glioblastoma (GBM) is the most invasive and common type of brain cancer with very poor prognosis. One of the drugs administered for GBM pharmacotherapy is etoposide (VP-16), which belongs to the topoisomerase inhibitor family. It can be used in combination with other drugs or chemicals to avoid high dose toxicities or augment its effect at lower doses. In this study we aimed to investigate whether high dose toxicities of etoposide can be overcome when used in combination with a natural compound named Rosmarinus Officinalis...
October 11, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/29091253/morphometric-study-of-the-human-brainstem-and-its-neurovascular-relations
#17
Bianca Aurora Szabo, Raluca Pascalau, Vlad Adrian Padurean
AIM: The brainstem is a very complex segment of the central nervous system because it has a high density of nuclei and tracts with vital functional roles. This explains the considerable difficulty of surgery for lesions located in or around the brainstem. Our paper aims to provide a concise description of the external configuration, its internal correspondence and the neurovascular relations of the brainstem with morphometric data that can be useful in surgical planning. MATERIAL AND METHODS: The study was conducted on formalin fixed brainstem specimens, which were harvested with respect to the topographic anatomy...
October 2, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/29091247/targeting-grp78-as-a-basis-for-enhanced-glioma-cells-killing-by-anti-tfr-antibody
#18
Xue Wen, Xiaoping Cheng, Si Wu
AIM: Studies have shown that chemotherapeutic drugs induced endoplasmic reticulum (ER) stress in glioblastoma cells. In our previous study, we have demonstrated anti-TfR monoclonal antibody 7579 enhanced the anti-tumor effects of chemotherapeutic drugs on human glioma cells in vitro. In our study, we therefore investigated whether the anti-TfR antibody alone or the combination of anti-TfR antibody with chemotherapeutic drug would lead to increased ER stress. MATERIAL AND METHODS: We detected ER stress after cells were treated with anti-TfR mAb or/and Nimustine by western blot analysis...
October 2, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/29091245/intracranial-epidermoid-lesions-our-experience-of-38-cases
#19
Lal Rehman, Iram Bokhari, Shamim Ul Siddiqi, Veejay Bagga, Muhammad Masood Hussain
BACKGROUND: The clinical outcome following surgical resection of intracranial epidermoid lesions is not well documented. We describe a case series evaluating the clinical presentation and outcome following surgery in patients diagnosed with these lesions. MATERIALS AND METHODS: A retrospective study conducted over a 4-year period. RESULTS: A total 38 patients who underwent surgery for intracranial epidermoid lesions were identified. Of these, 20 were supertentorial and 18 were infratentorial lesions...
October 2, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/29091254/evaluation-of-morphologic-and-morphometric-characteristic-of-foramen-transversarium-on-3-dimensional-multidetector-computed-tomography-angiography-mdcta
#20
Ayfer Metin Tellioglu, Yasemin Durum, Mustafa Gok, Ayse Gizem Polat, Can Zafer Karaman, Sacide Karakas
AIM: The aim of this study was to investigate the size and variations of the foramen transversarium (TF). In addition, to study the anatomical variations of vertebral artery entering the transverse foramen of the cervical vertebrae. MATERIAL AND METHODS: The images of 141 (90 males, 51 females) patients aged between 18-79 years (mean: 52.7 years) were analyzed. As a result, 987 cervical spines (C1-C7) and 1974 foramen transversariums were individually evaluated...
September 26, 2017: Turkish Neurosurgery
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