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Turkish Neurosurgery

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https://www.readbyqxmd.com/read/28191621/the-effect-of-ascorbic-acid-over-the-etoposide-and-temozolomide-mediated-cytotoxicity-in-glioblastoma-cell-culture-a-molecular-study
#1
Dilek Göktürk, Hasim Kelebek, Seda Ceylan, Derviş Mansuri Yilmaz
AIM: Glioblastoma (GBM) is one of the lethal central nervous system tumors. One of the widely used chemical agents for treatment of glioblastoma is temozolomide. It is an orally administered, DNA alkylating agent. DNA alkylation triggers the death of tumor cells. However, some tumor cells are able to repair this type of DNA damage, thus lower the therapeutic effect of temozolomide. Laboratory and clinical studies indicate that temozolomide\'s anticancer effects might be strengthened when combined with other chemotherapeutic agents, like etoposide, or antioxidant agents, like ascorbic acid...
January 19, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28191625/iatrogenic-vascular-injuries-due-to-spinal-surgeries-endovascular-perspective
#2
Mustafa Gok, Elcin Aydin, Serkan Guneyli, Ali Akay, Celal Cinar, Ismail Oran
AIM: Iatrogenic vascular injuries due to spinal surgeries are rare but serious complications. Surgical management of these injuries is challenging with high morbidity rates. In this study we aim to present the results of endovascular management of iatrogenic vascular injuries due to spinal surgeries. MATERIAL AND METHODS: We retrospectively reviewed 11 patients (5 male, 6 female) who had vascular injuries due to cervical and lumbar spinal surgeries. Clinical findings were bleeding (n=5), leg edema (n=6) and right heart failure with severe dyspnea (n=1)...
January 17, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28191623/the-ivy-sign-on-fluid-attenuated-inversion-recovery-images-related-to-single-photon-emission-computed-tomography-cerebral-blood-flow-in-moyamoya-disease-a-case-report
#3
Fumihiro Matano, Yasuo Murai, Asami Kubota, Takayuki Mizunari, Shiro Kobayashi, Akio Morita
BACKGROUND: Moyamoya disease is an idiopathic progressive cerebrovascular steno-occlusive disorder characterized by the formation of numerous collaterals called moyamoya vessels. Accurate evaluation of vascular status and CBF is needed for prompt treatment to prevent ischemic and/or hemorrhagic events. The pathogenesis of the ivy sign on fluid attenuated inversion recovery (FLAIR) images of moyamoya disease patients is unclear. We report a moyamoya disease case wherein the ivy sign changed in relation to SPECT-measured CBF during progression and following treatment...
January 17, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28191620/clinical-application-of-scalp-markers-and-three-dimensional-sliced-computer-tomography-reconstructions-of-the-skull-transverse-sigmoid-sinus-groove-in-the-retrosigmoid-approach
#4
Chao Wang, Han Guoqiang, Chao You, Chuangxi Liu
AIM: To explore the clinical value of bone flap creation and the sinus protection in the approach of retrosigmoid keyhole craniotomy with the guidance of three-dimensional (3D) sliced computer tomography (CT) reconstruction of the skull transverse sinus and sigmoid sinus groove. MATERIAL AND METHODS: The scalp tracings of the transverse sinus and sigmoid sinus groove of 108 posterior fossa lesion patients were delineated by gentian violet, which relies on the relationship between its 3D reconstruction location and scalp marker...
January 17, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28191622/embryonal-tumor-with-multilayered-rosettes-in-a-3-year-old-girl-case-report
#5
Aparna Govindan, Muralikrishnan Vp, Jacob Paul Alapatt
Embryonal tumor with multilayered rosettes(ETMR) is a new entity in the group of Primitive Neuroectodermal tumors of the central nervous system. It combines histopathological features of neuroblastoma and ependymoblastoma. This tumor occurs mostly in the first five years of life. A hallmark cytogenetic abnormality at the chromosome locus 19q13.42 has been identified. The authors report a case of ETMR in the parietooccipital region in a 3 year old girl who presented with features of raised intracranial tension...
January 8, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28191624/xanthomatous-meningioma-a-case-report
#6
Safak Ersoz, Zeynep Sagnak Yilmaz, İlker Eyüboglu, Ugur Yazar
Meningioma is a neoplasm derived from meningothelial cells. Grade1 meningiomas consist 9 different subtypes. One of the rare subtypes is metaplastic meningioma. Metaplastic meningioma could be defined as ''xanthomatous meningioma'' in the presence of prevalent xanthomatous changes. A 32 years old male patient had admitted to outpatient clinics with complaints of vertigo and tinnitus. Magnetic resonance imaging revealed a large mass of 7.4 cm in the right frontal region with an extra axial localization. Resection material demonstrated a neoplasm composed of classic meningothelial meningioma areas accompanied with areas of xanthomatous changes, containing cells with clear, vacuolated cytoplasm...
December 27, 2016: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28127724/risk-factors-and-compression-and-kyphosis-rates-after-1-year-in-patients-with-ao-type-a-thoracic-thoracolumbar-and-lumbar-fractures-treated-conservatively
#7
Feyza Karagoz Guzey, Burak Eren, Azmi Tufan, Ozgur Aktas, Cihan Isler, Mustafa Vatansever, Abdurrahim Tas, Eyup Cetin, Murat Yucel, Mustafa Ornek
AIM: Conservative treatment is a frequently used treatment modality for traumatic thoracolumbar fractures. However, not many studies evaluating radiological and clinical results of conservative treatment are found. The aim of this study was to determine the risk factors, and compression and kyphosis rates after 1 year in patients with AO type A thoracic, thoracolumbar, and lumbar fractures treated conservatively. MATERIAL AND METHODS: Radiological and clinical results of 79 thoracolumbar fractures in 57 patients, who were treated conservatively, were evaluated one year after trauma...
December 22, 2016: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28127723/obstructive-hydrocephalus-caused-by-an-unruptured-arteriovenous-malformation-successfully-treated-by-endoscopic-third-ventriculostomy-after-shunt-dysfunction
#8
Charles Champeaux, Céline Botella, Etienne Lefevre, Bertrand Devaux
The authors report on a patient harbouring an unruptured cortical arteriovenous malformation (AVM), who had presented with obstructive hydrocephalus due to compression of the cerebral aqueduct by a large venous varix. A ventriculoperitoneal (VP) shunt was inserted in emergency. Due to its large volume, the AVM was not referred for treatment and a follow-up policy was chosen. After the second VP shunt dysfunction, endoscopic third ventriculostomy was performed under neuronavigation. The procedure went uneventfully and the patient recovered well...
December 22, 2016: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28127722/magnetic-resonance-imaging-distortion-and-targeting-errors-from-strong-rare-earth-metal-magnetic-dental-implant-requiring-revision
#9
Park Seong-Cheol, Lee Chong Sik, Kim Seok Min, Choi Eu Jene, Lee Do Hee, Lee Jung Kyo
Recently, the use of magnetic dental implants has been re-popularized with the introduction of strong rare earth metal, for example, neodymium, magnets. Unrecognized magnetic dental implants can cause critical magnetic resonance image distortions. We report a case involving surgical failure caused by a magnetic dental implant. A 62-year-old man underwent deep brain stimulation for medically insufficiently controlled Parkinson's disease. Stereotactic magnetic resonance imaging performed for the first deep brain stimulation showed that the overdenture was removed...
December 22, 2016: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28094429/a-comparison-between-the-effectiveness-of-full-outline-of-unresponsiveness-and-glasgow-coma-score-at-neurosurgical-intensive-care-unit-patients
#10
Nail Caglar Temiz, Gulsah Kose, Ozkan Tehli, Cengizhan Acikel, Sevgi Hatipoglu
AIM: To evaluate the effectiveness and the use of Glasgow Coma Score (GCS) and Full Outline of Unresponsiveness (FOUR) score by nurses in the follow-up and evaluation of patients who admitted to neurosurgical intensive care unit for cranial surgery or head trauma. MATERIAL AND METHODS: The study was performed at a neurosurgical intensive care unit. Sample size was calculated 47 patients as 5% a, 95% Power and values less than 0.5 at correlation were accepted nonsense...
December 21, 2016: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28094427/minimalism-in-art-medical-science-and-neurosurgery
#11
Ali İhsan Ökten
The word ''minimalism'' is a word derived from French the word ''minimum''. Whereas the lexical meaning of minimum is ''the least or the smallest quantity necessary for something'', its expression in mathematics can be described as ''the lowest step a variable number can descend, least, minimal''. Minimalism, which advocates an extreme simplicity of the artistic form, is a current in modern art and music whose origins go to 1960s and which features simplicity and objectivity. Although art, science and philosophy are different disciplines, they support each other from time to time, sometimes they intertwine and sometimes they copy each other...
December 21, 2016: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28094430/comparison-of-sleep-quality-and-sleepiness-in-patients-operated-for-pituitary-adenoma-and-in-healthy-individuals
#12
Nail Caglar Temiz, Yunus Kacar, Royal Mehdiyev, Mehmet Can Ezgu, Omer Karakoc
AIM: To investigate whether sleep quality and sleepiness of patients who undergo surgery for pituitary adenomas differ from healthy individuals. MATERIAL AND METHODS: Forty-four patients who were operated for pituitary adenomas and 44 healthy individuals, 88 people in total, were evaluated by a questionnaire. All questionnaires and scales were made by the same researcher without the name of the participant in order to maintain consistency. Statistical analyzes were done with SPSS for Windows 23...
December 14, 2016: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28094428/intra-operative-results-and-post-operative-clinical-outcomes-of-lumbar-microdiscectomy-in-patients-received-transforaminal-anterior-epidural-steroid-injection-earlier-for-lumbar-radiculopathy
#13
Sait Ozturk, Bekir Akgun, Fatih Serhat Erol, Selami Ates Onal, Metin Kaplan
AIM: We have aimed to describe the intra and postoperative results of patients who received transforaminal anterior epidural steroid injection (TAESI) prior to undergoing lumbar microdiscectomy. MATERIAL AND METHODS: 64 of 2461 patients evaluated who had received minimally invasive technique (MIT) for lumbar radiculopathy and who felt no relief after the procedures. 32 patients of them treated with different techniques other than TAESI and those receiving thrombolytic or anticoagulant drugs before microdiscectomy were excluded...
December 14, 2016: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28094426/the-role-of-cine-flow-magnetic-resonance-imaging-in-patients-with-chiari-0-malformation
#14
Kerem Mazhar Ozsoy, Kadir Oktay, Nuri Eralp Cetinalp, Yurdal Gezercan, Tahsin Erman
AIM: The aim of this study was to define the role of phase-contrast cine magnetic resonance imaging in deciding the therapeutic strategy and underlying pathophysiology resulting in syrinx formation in patients with Chiari type 0 malformation. MATERIAL AND METHODS: Seven patients admitted to our clinic with diagnosis of Chiari 0 malformations during the period January 2005 to July 2016 were enrolled in the study. All patients underwent a detailed preoperative neurological examination...
December 14, 2016: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28094425/learning-curve-in-anatomo-electrophysiological-correlations-in-subthalamic-nucleus-stimulation
#15
Dušan Hrabovsky, Marek Balaz, Martina Bockova, Věra Feitova, Zdeněk Novak, Jan Chrastina
AIM: Advances in neuroradiological planning techniques in deep brain stimulation put the need for intraoperative electrophysiological monitoring into doubt. Moreover intraoperative monitoring prolongs surgical time and there is potential association between the use of microelectrodes and increased incidence of hemorrhagic complications Material and Methods: The study analyzes the correlation between the anatomically planned trajectory and the final subthalamic electrode placement after electrophysiological monitoring in patients with Parkinson's disease and its change with the increasing experience of the surgical team...
December 14, 2016: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28094431/chordoma-immunohistochemical-analysis-of-brachury
#16
İbrahim Sun, Mustafa Güdük, Bülent Güçyetmez, Özlem Yapicier, M Necmettin Pamir
AIM: Chordomas are rare, slow growing but locally aggressive malignancies of the axial skeleton. Skull base chordomas, due to their intricate anatomical localization pose significant challenges to managing physician. In classical and chondroid chordomas the disease course cannot be reliably determined using only morphological criteria. Brachyury (T Gene) was shown to play a central role in chordoma pathogenesis and several studies have also shown that this gene also caries potential as a prognostic biomarker...
December 12, 2016: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28032632/in-memorium-professor-m-kemali-baykaner-december-15-1949-september-21-2016
#17
Sukru Aykol, Fikret Dogulu, Memduh Kaymaz, Gokhan Kurt, Hakan Emmez, Alp Ozgun Borcek
No abstract text is available yet for this article.
2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/27593798/addendum-to-spinal-schwannomatosis-case-report-of-a-rare-condition
#18
Tayfun Hakan, Erhan Celikoglu, Fugen Aker, Nagehan Barisik
No abstract text is available yet for this article.
2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/27593772/publication-rates-of-presentations-at-annual-scientific-meetings-of-the-turkish-neurosurgical-society
#19
Murat Sakir Eksi, Sumeyye Coruh Kaplan, Baran Yilmaz, Akin Akakin, Zafer Orkun Toktas, Deniz Konya, Turker Kilic
AIM: National and international society meetings are suitable mediums at which diverse research topics from basic, clinical and translational sciences can be presented to an audience of peers. In this study, our purpose was to evaluate publication rates of presentations in the last recent four years" annual scientific meetings of Turkish Neurosurgical Society (TNS). MATERIAL AND METHODS: Abstracts of both podium and poster presentations were retrieved from the congress booklets of TNS...
2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/27593764/chronic-subdural-hematoma-preceded-by-high-impact-trauma-does-the-intensity-of-trauma-influence-the-pathogenesis-of-traumatic-chronic-subdural-hematoma
#20
Ki-Su Park, Chang-Heon Lee, Seong-Hyun Park, Sung-Kyoo Hwang, Jeong-Hyun Hwang
AIM: The purpose of this study was to investigate whether the intensity of trauma influences the pathogenesis of traumatic chronic subdural hematoma (CSDH). MATERIAL AND METHODS: Thirty-one patients treated surgically for traumatic CSDH were divided into high-impact and lowimpact groups according to the intensity of trauma. They were respectively evaluated with respect to clinical and radiological findings at presentation, and the subdural concentrations of interleukin-6 (IL-6), interleukin-8 (IL-8), vascular endothelial growth factor (VEGF), basic fibroblast growth factor, and beta-trace protein (ΒTP) [a highly specific protein in the cerebrospinal fluid (CSF)] related to the pathogenesis of CSDH...
2017: Turkish Neurosurgery
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