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Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición

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https://www.readbyqxmd.com/read/29943775/epidemiological-data-on-the-nutritional-status-of-cancer-patients-receiving-treatment-with-concomitant-chemoradiotherapy-radiotherapy-or-sequential-chemoradiotherapy-to-the-abdominopelvic-area
#1
Aurora Serralde-Zúñiga, Denisse Castro-Eguiluz, José Luis Aguilar-Ponce, Angélica Andrea Peña-Ruiz, Jorge Víctor Castro-Gutiérrez, Samuel Rivera-Rivera, Carlos Aranda-Flores, Verónica Casique-Pérez, Silvia Eugenia Alarcón-Barrios, Jaime de la Garza-Salazar, Miriam Sánchez-López, Alfonso Dueñas-González
Cancer patients are particularly susceptible to undernourishment so associated weight loss is frequent. Approximately 15% of patients lose >10% of their usual body weight, 40-80% become undernourished, and about 20% die as a result. Well-nourished patients have a higher survival rate when compared with patients at risk of undernourishment (19.9 vs. 3.7 months); hence, nutritional intervention is pivotal. Undernourishment negatively influences the patient's prognosis, and its prevalence depends on the tumor type and location, disease stage, treatment, and the applied nutritional evaluation tool...
2018: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/29943774/effects-of-dietary-components-during-and-after-concomitant-chemoradiotherapy-radiotherapy-or-sequential-chemoradiotherapy-to-the-abdominopelvic-area
#2
Laura Flores-Cisneros, Denisse Castro-Eguiluz, Diana Yolanda Reyes-Barretero, Emigdio Jaimes, Claudia Cano-Blanco, Carlos Avendaño-Pérez, Berenice Carbajal-López, Miriam Sánchez-López, Aida Mota-García, Dolores Gallardo-Rincón, Marce Inzunza-Soto, Claudia Hernandez-Quintero, Lucely Cetina-Pérez
Radiotherapy is a fundamental part of the treatment of pelvic neoplasms. Up to 90% of patients develop gastrointestinal symptoms as a result of acute injury to the small and large intestine, particularly in the mucosa. Radiotherapy leads to atrophy of the intestinal epithelium, acute crypt inflammation, inflammatory infiltration of the epithelium, malabsorption of lactose, and biliary salts as well as alterations in pancreatic enzymes and biliary salts, resulting in the malabsorption syndrome and dysbiosis...
2018: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/29943773/nutrient-recommendations-for-cancer-patients-treated-with-pelvic-radiotherapy-with-or-without-comorbidities
#3
Denisse Castro-Eguiluz, José Antonio Leyva-Islas, Julissa Luvian-Morales, Virginia Martínez-Roque, Miriam Sánchez-López, Guadalupe Trejo-Durán, Roberto Jiménez-Lima, Fanny Jocelyn Leyva-Rendón
Radiotherapy is one of the main treatment options used in pelvic cancers. Ionizing radiation induces damage to surrounding tissues, resulting in disruption of normal physiological functions and symptoms such as diarrhea, tenesmus, incontinence, and rectal bleeding, which can all significantly alter the patient's quality of life. These patients are at increased risk of developing protein-calorie malnutrition and micronutrient deficiencies. Therefore, designing a proper nutritional intervention plan, with an optimal proportion of protein, fat, and carbohydrates, is required to reduce or even reverse the patients' poor nutritional status, increase their tolerance and response to oncology treatment, decrease the rate of complications and improve their quality of life...
2018: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/29943772/nutritional-assessment-tools-for-the-identification-of-malnutrition-and-nutritional-risk-associated-with-cancer-treatment
#4
Lilia Castillo-Martínez, Denisse Castro-Eguiluz, Erika Thalia Copca-Mendoza, Dana Aline Pérez-Camargo, Carlos Alberto Reyes-Torres, Erika Alejandra-Damasco Ávila, Griselda López-Córdova, Maricruz Ruth Fuentes-Hernández, Lucely Cetina-Pérez, María Del Pilar Milke-García
Malnutrition and muscle wasting are common features of cancer cachexia that may interfere with the patient's response to cancer treatment, survival, and quality of life. An accurate nutritional screening at the time of diagnosis and throughout the patient's treatment fosters better control of the disease. Several screening tools have proven to be useful for this purpose. Nevertheless, nutritional evaluation is not a routine practice in this clinical setting and procedures must be standardized. Nutritional risk screening (NRS), malnutrition screening tool (MST), and patient-generated subjective global assessment (PG-SGA) are the most common screening tools, and each one possesses some benefits when screening patients for malnutrition; however, weight loss over a specific time period, dietary intake and anorexia must also be considered...
2018: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/29943771/epidemiological-profile-gastrointestinal-toxicity-and-treatment-of-pelvic-cancers-in-patients-managed-with-radiotherapy-to-the-abdominal-pelvic-area
#5
Lucely Cetina-Pérez, Alberto Serrano-Olvera, Laura Flores-Cisneros, Roberto Jiménez-Lima, Cristina Alvarado-Silva, María Del Consuelo Díaz-Romero, Flavia Morales-Vásquez, David Eduardo Muñoz-González, Aida Mota-García, Oscar Armando Chávez-Fierro, Silvia Cristina Jaramillo-Manzur, Jaime de la Garza-Salazar, Denisse Castro-Eguiluz, Abelardo Meneses-García
Mexico has seen an increase in cancer prevalence in its entire population as well as particular age ranges, predominantly the older segment. The most frequently reported pelvic cancers in Mexico are cervical, endometrial, bladder, prostate, rectum, and anal canal. Approximately 80% of the population diagnosed with pelvic cancers present with locally advanced tumors and require concomitant chemoradiotherapy, sequential chemoradiotherapy, or radiotherapy alone. The toxicity of any of these treatment modalities may be manifested as intestinal injury, a significant problem that can compromise the response to treatment, the patient's nutritional state, quality of life, and survival...
2018: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/29943770/nutrition-in-patients-with-cancer-treated-with-chemo-radiotherapy-to-the-abdominopelvic-area-a-consensus-report
#6
Lucely Cetina-Pérez, Denisse Castro-Eguiluz, Luis Fernando Oñate-Ocaña
No abstract text is available yet for this article.
2018: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/29943769/use-of-functional-foods-and-oral-supplements-as-adjuvants-in-cancer-treatment
#7
Guadalupe Serna-Thomé, Denisse Castro-Eguiluz, Vanessa Fuchs-Tarlovsky, Miriam Sánchez-López, Luis Delgado-Olivares, Jaime Coronel-Martínez, Eva María Molina-Trinidad, Martha de la Torre, Lucely Cetina-Pérez
In cancer patients treated with radiotherapy to the abdominopelvic region, dietary modifications and the use of functional foods (fortified food with added ingredients to provide specific health improving benefits, such as antioxidants, omega-3 fatty acids, and glutamine), may contribute to the improvement of the toxic effects of treatment, including nausea, diarrhea, and constipation, among others. With the aim of analyzing which coadjuvant foods benefit these patients, scientific evidence was gathered by a group of experts...
2018: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/29718013/ketamine-for-treatment-resistant-depression-a-new-advocate
#8
Rodrigo Pérez-Esparza
Current alternatives for the treatment of major depressive disorder lack efficacy and have a delayed onset of action. Recently, the glutamatergic neurotransmission system has been noted to play an important role in the pathophysiology of this disorder. Ever since the first report of the antidepressant effects of the N-methyl-D-aspartate receptor antagonist, ketamine, research has been redirected to novel therapeutic targets. With this rapidly growing evidence of a fast-acting antidepressant such as ketamine, as well as its efficacy in treatment-resistant cases of depression, off-label use has become popular in certain settings...
2018: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/29718012/schwann-cell-precursor-transplant-in-a-rat-spinal-cord-injury-model
#9
Oscar de la Garza-Castro, Herminia Guadalupe Martínez-Rodríguez, Sandra Gabriela Sánchez-González, Oscar Vidal-Torres, Azalea Arreola-Romero, Oscar de la Garza-Pineda, Adriana Guadalupe Ancer-Arellano, Santos Guzmán-López, Rodrigo Enrique Elizondo-Omaña
Background: Differentiation of mesenchymal stem cells into Schwann cell precursors could reverse established lesions and sequelae of medullary transection. Objective: The objective of this study was to study the clinical response of mesenchymal stem cell transplantation with Schwann precursor cell transplantation in a rat spinal cord injury model, using motor function and histopathologic studies. Materials and Methods: A total of 28 Sprague-Dawley rats were randomly divided among four groups (n = 7 in each): sham group, control group, mesenchymal stem cell transplant group, and Schwann cell precursor transplant group...
2018: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/29718011/association-of-intron-2-variable-numbers-of-an-86-bp-tandem-repeat-polymorphisms-of-interleukin-1-receptor-antagonist-gene-and-idiopathic-recurrent-spontaneous-abortion
#10
Marco Antonio Avila-Vergara, Felipe de Jesús Peraza-Garay, Noemí Meraz-Cruz, Cesar Hernandez-Guerrero, Berenice Palacios-Gonzalez, Felipe Vadillo-Ortega
Background: It has been proposed that abnormal modulation of inflammatory response is involved in the physiopathology of idiopathic recurrent spontaneous abortion (iRSA). Factors that may participate in this process include the genetic background such as carrying specific polymorphisms of genes with functional effects. Objective: The objective is to study the association between iRSA and the frequency of intron-2 variable number tandem repeat-polymorphisms of interleukin-1 receptor antagonist gene (IL1RN)...
2018: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/29718010/phenotypic-variability-in-a-mexican-mestizo-family-with-retinal-vasculopathy-with-cerebral-leukodystrophy-and-trex1-mutation-p-v235gfs-6
#11
Nancy Monroy-Jaramillo, Aurelio Cerón, Elizabeth León, Verónica Rivas, Adriana Ochoa-Morales, María Georgina Arteaga-Alcaraz, Fausto Carlos Nocedal-Rustrian, Cecilia Gallegos, María Elisa Alonso-Vilatela, Teresa Corona, José Flores
Background: Retinal vasculopathy with cerebral leukodystrophy (RVCL) is an adult-onset, autosomal dominant disease involving microvessels of the brain and eye resulting in central nervous system degeneration with visual disturbances, stroke, motor impairment, and cognitive decline. Frameshift mutations at the C-terminus of TREX1 gene are the molecular cause of this disorder. Objectives: The objective of this study is to present the different clinical manifestations of RVCL in three-related patients and to investigate the presence of TREX1 mutation in the extended genealogy...
2018: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/29718009/pulmonary-vasoreactivity-and-phenotypes-in-pulmonary-arterial-hypertension-associated-to-connective-tissue-diseases
#12
José Luis Hernández-Oropeza, Tatiana Sofía Rodríguez-Reyna, Diego Luis Carrillo-Pérez, José de Jesús Rodríguez-Andoney, René Narváez-David, Yesenia Salado-Morales, Eduardo Rivero-Sigarroa, Guillermo Domínguez-Cherit, Tomás Pulido-Zamudio
Background: Pulmonary arterial hypertension (PAH) is a fatal complication in patients with connective tissue disease (CTD). Objective: The objective of the study was to study the prognostic value of the acute pulmonary vasoreactivity test with inhaled iloprost and its association with clinical deterioration in a tertiary care academic medical center. Methods: We conducted a prospective study of patients with CTD and the diagnosis of PAH established by right heart catheterization...
2018: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/29718008/correlation-between-lung-and-joint-involvement-in-patients-with-rheumatoid-arthritis-and-interstitial-lung-disease-a-cross-sectional-study
#13
Francisco Paulin, Juan Francisco Mercado, Martín Eduardo Fernández, Fabián Matías Caro, María Laura Alberti, Leandro Alberto Fassola
Background: Rheumatoid arthritis (RA) can affect the lungs in different manners, with interstitial lung disease (ILD) as the most serious manifestation. Although lung and joint compromise could be thought to evolve in parallel, there are data suggesting the opposite. In this study, we evaluated the relationship between lung and joint involvement in RA ILD. Methods: An observational cross-sectional study of RA ILD patients evaluated from January 2015 to February 2017...
2018: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/29513304/a-prognostic-score-for-survival-in-patients-older-than-65-years-with-diffuse-large-b-cell-lymphoma
#14
Myrna Candelaria, Nancy Reynoso-Noverón, Mayra Ponce, Rodrigo Castillo-Llanos, Diana Nolasco-Medina, David Cantú-De-Leon
Background: Available prognosis scores for patients with diffuse large B-cell lymphoma (DLBCL) included a limited number of patients ≥ 65 years of age, and most of them did not include comorbidities. Here, we propose a prognostic score for overall survival (OS) for this group of patients. Materials and Methods: Patients ≥ 65 years with DLBCL treated at a single national reference center were included. Clinical features including comorbidities and biochemical parameters were analyzed...
2018: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/29513303/chewing-xylitol-gum-could-accelerate-bowel-motility-recovery-after-elective-open-proctectomy-for-rectal-cancer
#15
Ping Yang, Wu Jun Long, Li Wei
Background: A number of studies with conflicting results have evaluated the effect of chewing gum on post-operative gastrointestinal recovery in patients after major colorectal surgery. Objective: The objective of the study was to study the efficacy of chewing gum in patients with rectal cancer after elective open proctectomy only. Methods: A randomized controlled clinical trial was performed. We recruited patients who would undergo elective open proctectomy for rectal cancer in Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital...
2018: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/29513302/innate-immunity-in-coronary-disease-the-role-of-interleukin-12-cytokine-family-in-atherosclerosis
#16
Rosalinda Posadas-Sánchez, Gilberto Vargas-Alarcón
Atherosclerosis is a chronic, progressive, and multifactorial disease modulated by genetic and environmental factors. In recent years, the paradigm that explained atherosclerosis as resulting from a complex interaction between factors not accessible to medical intervention, and modifiable risk factors has changed. In this paradigm, alterations in lipid metabolism were the pivotal concept of atherosclerosis as a chronic degenerative disease. In the last years, an increasing number of observations have shown that the innate and adaptive immune responses to lipoprotein deposition and oxidation in the arterial wall significantly influence atherosclerosis...
2018: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/29513301/changing-trends-in-gastric-polyps
#17
Magali Evangelina Velázquez-Dohorn, Carlos Fernando López-Durand, Armando Gamboa-Domínguez
Background: The prevalence of gastric polyps varies around the world reflecting regional associations. We describe demographic features of patients with gastric polyp diagnosis treated between 1980 and 2016 at a referral center in Mexico City and analyzed trends of polyp subtype. Materials and Methods: We conducted a blind review of archival slides of gastric biopsies with polyp diagnosis from the years 1980, 1990, 2000, 2010, and 2016. Initial diagnosis; patient's gender, age and symptoms; and number and location of lesions were recorded...
2018: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/29513300/heading-toward-the-elimination-of-hepatitis-c-virus
#18
David Kershenobich, Aldo Torre-Delgadillo, Luz María Aguilar-Valenzuela
Chronic hepatitis C is often asymptomatic and may progress over the years to cirrhosis and hepatocellular carcinoma. Although the prevalence and incident cases are decreasing, the peak mortality of hepatitis C virus (HCV)-related complications is ahead of us in most countries. The economic impact of this burden is enormous. Scaling up the identification of new opportunities to facilitate the road toward HCV elimination includes increasing screening, awareness, and the number of prescribing physicians. Screening should occur within the context of linkage-to-care and patient retention across the care continuum...
2018: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/29513299/cytotoxic-activity-of-a-black-bean-phaseolus-vulgaris-l-extract-and-its-flavonoid-fraction-in-both-in-vitro-and-in-vivo-models-of-lymphoma
#19
Ulises Aregueta-Robles, Oscar R Fajardo-Ramírez, Luis Villela, Janet A Gutiérrez-Uribe, José Hernández-Hernández, Rosa Del Carmen López-Sánchez, Sean-Patrick Scott, Sergio Serna-Saldívar
Background: Black bean (Phaseolus vulgaris L.) is a very common legume seed in Mexican diet. Flavonoids and crude extracts from different plants have been reported as effective agents for chemoprevention and cytotoxicity in several cancer cell lines. We investigated the effects of black bean hulls extract (BBE) and its flavonoid fraction (FF) on lymphoma cells. Methods: BBE and FF were characterized by high-performance liquid chromatography. Viability and flow cytometry assays were carried out...
2018: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/29513298/nod2-activation-during-bacterial-and-viral-infections-polymorphisms-and-potential-as-therapeutic-target
#20
Diana Alhelí Domínguez-Martínez, Daniel Núñez-Avellaneda, Carlos Alberto Castañón-Sánchez, Ma Isabel Salazar
Nucleotide-binding domain (NBD) leucine-rich repeat (LRR)-containing receptors or NLRs are a family of receptors that detect both, molecules associated to pathogens and alarmins, and are located mainly in the cytoplasm. NOD2 belongs to the NLR family and is a dynamic receptor capable of interacting with multiple proteins and modulate immune responses in a stimuli-dependent manner. The experimental evidence shows that interaction between NOD2 structural domains and the effector proteins shape the overall response against bacterial or viral infections...
2018: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
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