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Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición

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https://www.readbyqxmd.com/read/28239182/psoriasis-in-children-and-adolescents-epidemiological-study-of-280-patients-from-mexico
#1
Andrea Tovar-Garza, Mayela Meza-Resendiz, Elizabeth Guevara-Gutiérrez, Juan Gabriel Barrientos-García, Alberto Tlacuilo-Parra
BACKGROUND: Psoriasis in children and adolescents has not been well studied in Mexico. OBJECTIVE: To study the epidemiological characteristics of psoriasis in this age group. METHODS: This is a retrospective study in an academic, tertiary care dermatology center from January 1999 to December 2014. We included patients ≤ 18 years of age, with clinical and histopathological diagnosis of psoriasis. We recorded the following information: gender, age, disease duration, clinical variant, nail involvement, treatment, and family history...
January 2017: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/28239181/high-dietary-magnesium-intake-is-significantly-and-independently-associated-with-higher-insulin-sensitivity-in-a-mexican-mestizo-population-a-brief-cross-sectional-report
#2
Carlos Moctezuma-Velázquez, Miguel Ángel Gómez-Sámano, María Belén Cajas-Sánchez, Diana Lorena Reyes-Molina, Mariana Galindo-Guzmán, Clara-Elena Meza-Arana, Daniel Cuevas-Ramos, Francisco Javier Gómez-Pérez, Alfonso Gulias-Herrero
BACKGROUND: Magnesium acts as a cofactor in many intracellular reactions including phosphorylation of the insulin receptor; therefore, its imbalance can potentially cause insulin resistance. Low serum magnesium concentration has been associated with the development of metabolic syndrome and type 2 diabetes mellitus. OBJECTIVE: To study the association between the daily dietary magnesium intake and insulin resistance estimated by the homeostatic model assessment of insulin resistance and homeostatic model assessment 2, as well as insulin sensitivity estimated by the Matsuda index...
January 2017: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/28239180/clinical-and-demographic-predictors-of-conversion-to-dementia-in-mexican-elderly-with-mild-cognitive-impairment
#3
Sara G Aguilar-Navarro, Alberto J Mimenza-Alvarado, José Alberto Ávila-Funes, Teresa Juárez-Cedillo, Carolina Bernal-López, Celia G Hernández-Favela
BACKGROUND: Mild cognitive impairment (MCI) is considered a clinical stage between normal cognitive aging and dementia. The clinical course of MCI is heterogeneous, with a significant number of cases progressing to dementia or reverting back to normal. OBJECTIVE: To determine the predictors of conversion from mild cognitive impairment to dementia among Mexican older adults. MATERIALS AND METHODS: A sample of 175 persons underwent clinical and neuropsychological evaluation to establish mild cognitive impairment diagnosis...
January 2017: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/28239179/unsuspected-lung-pathology-in-autopsies-of-children-with-cancer
#4
María Elena Y Furuya, Alicia Rodríguez-Velasco, María Carmen Rodríguez-Zepeda, Enrique López-Aguilar, Mario H Vargas, Martha Sciandra-Rico, Rocío Cárdenas-Navarrete, Olivia Madrigal-Muñiz, Carina Feria-Kaiser, Elba E Delgado-González, Miguel Ángel Villasís-Keeverz
BACKGROUND: Although pulmonary involvement is common in patients with cancer, its frequency and nature is seldom reported in the medical literature. OBJECTIVE: To determine the frequency and type of lung pathological conditions revealed by autopsy in children with cancer. METHODS: All reports from autopsies performed in children with cancer from 1989 to 2012 in a pediatric hospital were reviewed. RESULTS: In the analyzed period, 118 autopsies (10...
January 2017: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/28239178/prevalence-and-characteristics-of-exercise-induced-bronchoconstriction-in-high-school-and-college-athletes-at-2-240-m-altitude
#5
Martín Becerril-Ángeles, Mario H Vargas, Leonardo Hernández-Pérez, Nancy Judith Rivera-Istepan, Rebeca Ivonne Pérez-Hidalgo, Ana Gabriela Ortega-González, Severino Rubio-Domínguez, María Cristina Rodríguez-Gutiérrez, Radamés Gaxiola-Cortés, Rodrigo Dosal-Ulloa, Laura Graciela Gochicoa-Rangel
BACKGROUND: Athletes practicing strenuous physical activities may develop exercise-induced bronchoconstriction (EIB). We aimed to determine the prevalence and features of this condition in Mexico City (altitude, 2,240 m). METHODS: In the present study, 208 high school and college athletes performed a standardized EIB test on a treadmill. RESULTS: Responses to exercise had large between-subject variability in all physiological parameters (forced expiratory volume in one second [FEV1], heart rate, blood oxygen saturation level [SpO2], blood pressure), with nearly similar proportions of subjects in whom FEV1 increased or decreased...
January 2017: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/28239177/radiotherapy-for-metastatic-breast-cancer-in-mexico-results-from-the-2015-national-survey
#6
Nora Álvarez-Águila, Hilary Cook, Diddier Prada, Aida Mota-García, Luis A Herrera, Alejandro Mohar-Betancourt, Abelardo Meneses-García, Felicia M Knaul
BACKGROUND: Radiation therapy is a keystone to improve survival and quality of life in breast cancer patients. In Mexico, however, scarce information is available on the obstacles faced by radio-oncologists to provide appropriate treatment. OBJECTIVE: To determine the most frequent issues faced by physicians to provide radiation therapy for metastatic breast cancer in Mexico. METHODS: A survey of 16 multiple-choice questions to be answered electronically by 167 radio-oncologists currently working in Mexico was designed and thereafter analyzed for differences between private and public practices, based on the responses from the surveyed participants...
January 2017: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/28239176/the-role-of-nramp1-slc11a1-gene-variant-d543n-1730g-a-in-the-genetic-susceptibility-to-develop-rheumatoid-arthritis-in-the-mexican-mestizo-population
#7
Perla Niño-Moreno, Edgar Turrubiartes-Martínez, Brenda Oceguera-Maldonado, Nubia Baltazar-Benítez, Cindy Negrete-González, Brenda Oliva-Ramírez, Lourdes Baranda, Roberto González-Amaro
BACKGROUND: Rheumatoid arthritis is a chronic inflammatory disease whose cause has not been fully elucidated. However, genetic factors seem to have an important role in its pathogenesis. OBJECTIVE: We analyzed the possible association between rheumatoid arthritis and variants of the SLC11A1 gene, which encodes for NRAMP1, a protein involved in the activation of phagocytes and synthesis of proinflammatory cytokines. METHODS: In a case-control study in a Mexican Mestizo population, blood samples from 188 patients with rheumatoid arthritis and 133 healthy individuals were obtained to determine the frequency of SLC11A1 gene variants INT4 (469+14G/C or rs3731865), D543N (1730G/A or rs17235409) and 3'UTR (1729+55del4 or rs17235416) by polymerase chain reaction and restriction fragment length polymorphism...
January 2017: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/28134943/usefulness-of-gum-chewing-to-decrease-postoperative-ileus-in-colorectal-surgery-with-primary-anastomosis-a-randomized-controlled-trial
#8
Omar Vergara-Fernandez, Ana Prixila Gonzalez-Vargas, Juan Carlos Castellanos-Juarez, Noel Salgado-Nesme, Emilio Sanchez-Garcia Ramos
BACKGROUND: Postoperative ileus generates a high impact on morbidity, hospital stay, and costs. OBJECTIVE: To study the efficiency and safety of chewing gum to decrease postoperative ileus in colorectal surgery. METHOD: A randomized controlled trial was performed including 64 patients who underwent elective colorectal surgery with primary anastomosis in a tertiary referral center. Patients were divided in two groups: (i) A: gum chewing group (n = 32), and (ii) B: patients who had standard postoperative recovery (n = 32)...
November 2016: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/28134942/impact-of-aberrant-antigens-in-the-outcome-of-patients-with-acute-leukemia-at-a-referral-institution-in-mexico-city
#9
Sergio Rodríguez-Rodríguez, Alan Pomerantz, Roberta Demichelis-Gómez, Georgina Barrera-Lumbreras, Olga V Barrales-Benítez, Xavier Lopez-Karpovitch, Álvaro Aguayo
BACKGROUND: Patients with acute leukemia can express aberrant markers, defined as antigens that are normally restricted to a different lineage. The reported significance and frequency of these markers is inconclusive. We assessed the frequency and impact of aberrant markers in patients with acute leukemia in a referral institution in Mexico City. METHODS: We included 433 patients, diagnosed and treated between 2005 and 2015 in our institution. RESULTS: Aberrant markers were expressed in 128 patients (29...
November 2016: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/28134941/advantages-of-minimally-invasive-surgery-for-the-treatment-of-colovesical-fistula
#10
Noel Salgado-Nesme, Omar Vergara-Fernández, Luis Alberto Espino-Urbina, Hugo Alberto Luna-Torres, Adolfo Navarro-Navarro
BACKGROUND: Colovesical fistulas in two-thirds of the cases are due to diverticular disease. In recent years, a minimally invasive approach has shown advantages over the traditional open approach. The goal of this study was to evaluate the surgical results and safety of the laparoscopic procedure in patients with colovesical fistula. MATERIAL AND METHODS: We retrospectively evaluated 24 patients who underwent surgery for colovesical fistula in a referral center from 2005 to 2011...
November 2016: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/28134940/the-neuroprotective-effect-of-erythropoietin-in-rat-hippocampus-in-an-endotoxic-shock-model
#11
Luis Javier Ramírez-Jirano, Tania Zenteno-Savín, Ramón Gaxiola-Robles, Elsy Janeth Ramos-González, Blanca Miriam Torres-Mendoza, Oscar Kurt Bitzer-Quintero
BACKGROUND: Sepsis is characterized by an early systemic inflammation in response to infection. In the brain, inflammation is associated with expression of pro-inflammatory cytokines (e.g. tumor necrosis factor-α, interleukin-1β and interleukin-6, among others) that may induce an overproduction of reactive oxygen and nitrogen species. The constitutive expression of cytokines in the brain is low, but may be induced by various stimuli, including lipopolysaccharide, which causes neuronal damage...
November 2016: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/28134939/the-type-of-trypanosoma-cruzi-strain-native-or-non-native-used-as-substrate-for-immunoassays-influences-the-ability-of-screening-asymptomatic-blood-donors
#12
Martha A Ballinas-Verdugo, Ana M Mejía-Domínguez, Sergio A Sánchez-Guerrero, Claudia Lerma, Mariana Martínez-Cruz, Elsa Álvarez-Manilla-Toquero, Xochiquetzali Jiménez-Díaz, Francelia Barrera-Trujillo, Marisela Del R Ticante-Cruz, Irving O Estevez-Garcia, Luis M Amezcua-Guerra, Pedro A Reyes-Lopez
BACKGROUND: The origin (native or non-native) of Trypanosoma cruzi strains used as substrate for immunoassays may influence their performance. OBJECTIVE: To assess the performance of an immunoassay based on a native T. cruzi strain compared to another based on non-native T. cruzi strains, in asymptomatic blood donors from Mexico. METHODS: Serum samples from a tertiary referral center were tested by both ELISA-INC9 (native) and Chagatest (non-native) assays...
November 2016: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/28134938/obstructive-sleep-apnea-and-perinatal-risk
#13
Margarita Reyes-Zúñiga, Luis Torre-Bouscoulet
Obstructive sleep apnea is characterized by total or partial interruptions of airflow during sleep, despite ongoing efforts to breathe. These pauses result from repeated upper airway obstructions that generate a systemic inflammatory condition with consequences for the endothelial function that increase the risk of cardiometabolic events. The prevalence of obstructive sleep apnea during pregnancy is greater than that observed in the general population and increases in the third trimester. Although limited, the information currently available supports the notion that obstructive sleep apnea is an independent, and potentially modifiable, risk factor for maternal and perinatal morbidity and mortality...
November 2016: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/27941963/clinical-and-genetic-findings-in-mexican-patients-with-duane-anomaly-and-radial-ray-malformations-okihiro-syndrome
#14
Óscar F Chacón-Camacho, Jesús Cabral-Macías, Raúl Ayala-Ramírez, Jazmín Arteaga-Vázquez, Yevgeniya Svyryd, Karla Helmes, Nohemí Pérez-Hernández, Osvaldo M Mutchinick, Juan Carlos Zenteno
BACKGROUND: Okihiro syndrome is an autosomal-dominant condition characterized by radial ray malformations associated with Duane anomaly and other clinical characteristics. SALL4 mutations have been identified in 80-90% of patients with Duane- Radial ray defects/Okihiro syndrome. We report the clinical findings and results of SALL4 sequencing from a group of Mexican patients with this disorder. OBJECTIVE: Clinical description and identification of SALL4 mutations in Mexican subjects with radial defects and Duane anomaly...
September 2016: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/27941962/microalbuminuria-and-its-association-with-subclinical-atherosclerosis-in-the-mexican-mestizo-population-the-gea-study
#15
Aida Medina-Urrutia, Juan Gabriel Juárez-Rojas, Rosalinda Posadas-Sánchez, Esteban Jorge-Galarza, Guillermo Cardoso-Saldaña, Gilberto Vargas-Alarcón, Rocío Martínez-Alvarado, Carlos Posadas-Romero
BACKGROUND: Microalbuminuria is an early marker of atherosclerosis. Ethnic differences for both conditions have been reported. We studied microalbuminuria prevalence and its association with coronary artery calcification as an early atherosclerosis marker in a Mexican-Mestizo population free of diabetes and hypertension (healthy), as well as in hypertensive and diabetic subjects. METHODS: In 1,472 adults (53.3 ± 9.4 years old, 50.3% women), anthropometric measurements, fasting blood glucose, and lipid profile were determined...
September 2016: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/27941961/therapeutic-effects-of-bipolar-coagulation-forceps-on-open-thyroid-surgery
#16
Lei Su, Jiayong Li, Xiaoqiao Tang, Jianfeng Sang
BACKGROUND: The aim was to compare the therapeutic effects of bipolar coagulation forceps, harmonic scalpel, and conventional thyroidectomy on open thyroid surgery. METHODS: A total of 527 patients who received open thyroid surgery in the Affiliated Drum Tower Hospital of Nanjing University Medical School between February 2013 and February 2016 were randomly divided into three groups: bipolar coagulation forceps, harmonic scalpel, and conventional thyroidectomy...
September 2016: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/27941960/gender-differences-in-quantitative-electroencephalogram-during-a-simple-hand-movement-task-in-young-adults
#17
Jessica Cantillo-Negrete, Rubén Isaac Carino-Escobar, Paul Carrillo-Mora, Teodoro Bernardo Flores-Rodríguez, David Elías-Vinas, Josefina Gutiérrez-Martínez
BACKGROUND: No consensus has been reached regarding the existence of gender differences during motor tasks in electroencephalography. This could lead to misinterpretation of electroencephalography clinical diagnosis and affect the calibration of brain-computer interfaces. OBJECTIVE: To assess whether there are statistically significant gender differences in electroencephalography recorded during hand movements. METHODS: Electroencephalography data were recorded from 18 women and 18 men while performing hand movements and rest...
September 2016: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/27941959/acute-respiratory-distress-syndrome-secondary-to-influenza-a-h1n1-pdm09-clinical-characteristics-and-mortality-predictors
#18
Carmen Margarita Hernández-Cárdenas, Héctor Serna-Secundino, José Guadalupe García-Olazarán, Cristina Leticia Aguilar-Pérez, Jesús Rocha-Machado, Luis Fernando Campos-Calderón, Gustavo Lugo-Goytia
BACKGROUND: Acute respiratory distress syndrome secondary to influenza A(H1N1)pdm09 virus is the leading cause of death among this patient population. Expanding the knowledge of its course and predictors of mortality is relevant to decision making. We aimed to describe the clinical characteristics and identify factors associated with mortality in patients with acute respiratory distress syndrome secondary to influenza A(H1N1)pdm09 during the 2013-2014 influenza season. METHODS: This is an observational study of a prospective cohort of 70 patients with acute respiratory distress syndrome and influenza A(H1N1) pdm09 seen in an academic medical center...
September 2016: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/27941958/adherence-to-a-gluten-free-diet-in-mexican-subjects-with-gluten-related-disorders-a-high-prevalence-of-inadvertent-gluten-intake
#19
Karen Lizzette Ramírez-Cervantes, Angélica Viridiana Romero-López, Carlos Alberto Núñez-Álvarez, Luis F Uscanga-Domínguez
BACKGROUND: The rate of compliance with a gluten-free diet in patients with gluten-related disorders is unknown in most Latin American countries. OBJECTIVE: To study the adherence to a gluten-free diet of Mexican individuals with celiac disease and nonceliac gluten sensitivity at the time of their first medical and nutritional consultation at a tertiary referral center. METHODS: A cross-sectional study was performed. A specific questionnaire was used to gather information on demographics, clinical condition, and self-reported adherence to a gluten-free diet, and to determine strict compliance and intentional or inadvertent gluten consumption...
September 2016: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/27941957/invasive-and-complicated-pneumococcal-infection-in-patients-with-cancer
#20
Sugehily Zarco-Márquez, Patricia Volkow-Fernández, Consuelo Velázquez-Acosta, Gabriela Echániz-Avilés, María Noemí Carnalla-Barajas, Araceli Soto-Noguerón, Patricia Cornejo-Juárez
BACKGROUND: In susceptible patients, Streptococcus pneumoniae can cause complicated pneumonia and invasive pneumococcal disease. The aim of this study was to assess the clinical and antimicrobial features of complicated and invasive pneumococcal disease in patients with cancer. METHODS: We conducted a retrospective study including all S. pneumoniae isolates between January 1, 2007 and December 31, 2015 in an oncology center. Capsular serotyping was done in isolates from sterile sites...
September 2016: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
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