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Facial Plastic Surgery Clinics of North America

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https://www.readbyqxmd.com/read/30213432/biologic-treatments-are-our-future-but-a-more-regulated-one
#1
EDITORIAL
Gregory S Keller
No abstract text is available yet for this article.
November 2018: Facial Plastic Surgery Clinics of North America
https://www.readbyqxmd.com/read/30213431/mesothelial-stem-cells-and-stromal-vascular-fraction-for-skin-rejuvenation
#2
REVIEW
David A Wolf, William Beeson, John D Rachel, Gregory S Keller, C William Hanke, Jill Waibel, Matt Leavitt, Michael Sacopulos
The use of stem cells in regenerative medicine and specifically facial rejuvenation is thought provoking and controversial. Today there is increased emphasis on tissue engineering and regenerative medicine, which translates into a need for a reliable source of stem cells in addition to biomaterial scaffolds and cytokine growth factors. Adipose tissue is currently recognized as an accessible and abundant source for adult stem cells. Cellular therapies and tissue engineering are still in their infancy, and additional basic science and preclinical studies are needed before cosmetic and reconstructive surgical applications can be routinely undertaken and satisfactory levels of patient safety achieved...
November 2018: Facial Plastic Surgery Clinics of North America
https://www.readbyqxmd.com/read/30213430/mesenchymal-stem-cells-and-stromal-vascular-fraction-for-hair-loss-current-status
#3
REVIEW
Gorana Kuka Epstein, Jeffrey S Epstein
The current state of the applicability of cell therapy for the treatment of various conditions of hair loss reveals a promising and potentially effective role. Further research, based on published work to date, is indicated to further explore the potential roles of autologous fat grafting, mesenchymal stem cells, and stromal vascular fraction therapy. The authors' evolving experience matches these promising scientific findings.
November 2018: Facial Plastic Surgery Clinics of North America
https://www.readbyqxmd.com/read/30213429/mesothelial-stem-cells-and-stromal-vascular-fraction-use-in-functional-disorders-wound-healing-fat-transfer-and-other-conditions
#4
REVIEW
Greg Chernoff, Nathan Bryan, Andrea M Park
Autologous human fat-derived mesenchymal stem cells are present in stromal vascular fraction. Stromal vascular fraction can be easily and safely extracted from lipoaspirate. The regenerative, antiinflammatory and immunomodulatory effects of stromal vascular fraction are being documented in ongoing therapeutic response studies.
November 2018: Facial Plastic Surgery Clinics of North America
https://www.readbyqxmd.com/read/30213428/platelet-rich-plasma-for-hair-loss-review-of-methods-and-results
#5
REVIEW
Karam W Badran, Jordan P Sand
Given substantial advances in hair regrowth research and platelet-rich plasma (PRP) science, a review of currently used systems and results is informative for physicians using a biologics approach to hair restoration. Overall positive clinical response to the use of PRP in androgenetic and alopecia areata patients is observed. The effects on hair density, count, and thickness were demonstrated through multiple clinical trials. Use as an adjunct to hair transplantation and with other technologies is also described...
November 2018: Facial Plastic Surgery Clinics of North America
https://www.readbyqxmd.com/read/30213427/lasers-microneedling-and-platelet-rich-plasma-for-skin-rejuvenation-and-repair
#6
REVIEW
Karam W Badran, Vishad Nabili
Skin resurfacing for the purpose of rejuvenation and repair continues to evolve with the development of noninvasive or minimally invasive surgical substitutes. Advances in laser therapy, microneedling, and platelet-rich plasma have reinvigorated research in wound repair and regenerative science. An overall positive clinical response toward the use of platelet-rich plasma as an adjuvant to fractional photothermolysis and percutaneous collagen induction is observed. Its effect on post-treatment adverse symptoms, erythema, edema, crusting, and clinical outcomes in rejuvenation are summarized in this article...
November 2018: Facial Plastic Surgery Clinics of North America
https://www.readbyqxmd.com/read/30213426/microneedling-with-biologicals-advantages-and-limitations
#7
REVIEW
Diane Irvine Duncan
Microneedling is a popular and cost-effective treatment with little down time. The application of topical agents to enhance outcomes is common practice. Microchannels created with nonthermal needling close at 4 hours to 6 hours due to fibrin plugs. Channels created with thermal needling or fractional laser stay open longer and enhance drug or biological uptake more due to the dermal sponge injury pattern that is created. Nonthermal microneedling devices may need Food and Drug Administration clearance, which also notes that dermaceuticals should be considered drugs in many cases...
November 2018: Facial Plastic Surgery Clinics of North America
https://www.readbyqxmd.com/read/30213425/platelet-rich-plasma-for-skin-rejuvenation-and-tissue-fill
#8
REVIEW
Jiahui Lin, Anthony P Sclafani
Platelet preparations, including platelet-rich plasma and platelet-rich fibrin matrix, have been used to improve wound healing, recovery time, and cosmetic outcomes for facial rejuvenation. Bioactive growth factors released from platelets are the putative agents in producing a reparative tissue reaction in the treated area. Different methods of processing the patients' blood will yield different types of platelet preparations with different components and properties, and it is important to understand these differences and their potential implications...
November 2018: Facial Plastic Surgery Clinics of North America
https://www.readbyqxmd.com/read/30213424/stem-cells-in-dermatology-and-anti-aging-care-of-the-skin
#9
REVIEW
Amy Forman Taub, Kim Pham
Multipotent stem cells have paved the way for new applications and deeper understanding in regenerative medicine and the pathophysiology of aging. During skin aging, cumulative photodamage, exhaustion of endogenous stem cell populations, mechanical stress, and increased fibrosis lead to skin with decreased epidermal thickness and compromised dermal integrity. Specific stem cells in the hair follicle create new keratinocytes after activation by defensin peptides, released by neutrophils during wounding. Studies pertaining to defensin peptides' efficacy on skin aging have been published, highlighting their potential as a new therapy for skin rejuvenation...
November 2018: Facial Plastic Surgery Clinics of North America
https://www.readbyqxmd.com/read/30213423/hair-biology-growth-and-pigmentation
#10
REVIEW
Andrea M Park, Sajjad Khan, Jeffrey Rawnsley
Healthy hair is vital to identity. Understanding the intricate anatomy and physiology of hair provides insight into the aging process and the eventual loss of either hair pigmentation or hair shafts. Several biologics are available that have enabled altering or slowing the aging process of hair, but, unfortunately, no agent exists that can reverse the natural course. The commonly used biologics are discussed.
November 2018: Facial Plastic Surgery Clinics of North America
https://www.readbyqxmd.com/read/30213422/how-to-use-oral-and-topical-cosmeceuticals-to-prevent-and-treat-skin-aging
#11
REVIEW
Leslie Baumann
Skin aging is caused by DNA damage in nuclei and mitochondria, inflammation, glycation, decreased function of keratinocytes and fibroblasts and breakdown of heparan sulfate, hyaluronic acid, collagen, and elastin. Identifying patients at an increased risk of skin aging using a standardized methodology to diagnose the Baumann Skin Type will allow doctors to prescribe an efficacious antiaging skin care regimen. Cosmeceuticals can activate LGR6+ stem cells, improve cell response to signals such as growth factors, stimulate collagen genes, neutralize free radicals, and decrease breakdown of collagen and elastin...
November 2018: Facial Plastic Surgery Clinics of North America
https://www.readbyqxmd.com/read/30213421/introduction-an-overview
#12
REVIEW
Gregory S Keller, Andrea M Park
The use of biologicals for clinical use is rapidly increasing. One of the logical questions is what constitutes a biological? The official definition of biological products by the Food and Drug Administration is "Biological products can be composed of sugars, proteins, or nucleic acids, or a combination of these substances. They may also be living entities, such as cells and tissues. Biologics are made from a variety of natural resources-human, animal, and microorganism-and may be produced by biotechnology methods...
November 2018: Facial Plastic Surgery Clinics of North America
https://www.readbyqxmd.com/read/30078396/truly-asian-rhinoplasty
#13
EDITORIAL
Yong Ju Jang
No abstract text is available yet for this article.
August 2018: Facial Plastic Surgery Clinics of North America
https://www.readbyqxmd.com/read/30005794/rhinoplasty-for-south-east-asian-nose
#14
REVIEW
Eduardo C Yap
The South East Asian nose is usually small with voluminous thick skin, low dorsum, wide and hanging ala, bulbous tip, and retracted premaxilla. The surgical approach of rhinoplasty for these types of noses includes the following: dorsal augmentation, counterrotation and projection of the tip, and correction of hanging ala and alar flare/base. A usual ideal rhinoplasty outcome of a South East Asian nose should be a nose that fits the face with good function and has all the aesthetic landmarks achieved: natural looking dorsum, supratip break, tip, subtip break, columellar show, good alar-columellar relationship, improved premaxilla, improved nostril, and improved alar flare...
August 2018: Facial Plastic Surgery Clinics of North America
https://www.readbyqxmd.com/read/30005793/correction-of-short-nose
#15
REVIEW
Dong Hak Jung, Sang Gyun Jin, Sang Min Hyun
To correct an Asian short nose with low dorsum, short columella, and poorly defined nose tip, augmentation rhinoplasty has been popularized. A simple augmentation no longer is considered an efficient rhinoplasty approach for Asians aesthetically; most surgeons simultaneously perform nasal elongation and augmentation during rhinoplasty. To extend the nose length successfully, important factors are cartilages, mucosal and skin conditions, and presence and degree of fibrotic changes. In addition, surgeons should consider preoperatively how much should be extended from an aesthetics perspective...
August 2018: Facial Plastic Surgery Clinics of North America
https://www.readbyqxmd.com/read/30005792/alar-base-reduction-and-alar-columellar-relationship
#16
REVIEW
Ji Yun Choi
Nasal base modification can improve nostril shape and orientation, reduce alar flaring, improve nasal base width, correct nasal hooding, improve symmetry, and create overall facial harmony. For the correction of alar rim deformities, careful examination, consultation, and analysis and consideration of the condition of the skin are essential. Understanding the ala and surrounding tissue, supporting the lower lateral cartilage, and selecting the proper technique produce functionally and aesthetically good results...
August 2018: Facial Plastic Surgery Clinics of North America
https://www.readbyqxmd.com/read/30005791/hump-nose-correction-in-asians
#17
REVIEW
Tae-Bin Won
Nasal hump surgery is frequently regarded as a reduction surgery in most Western rhinoplasty textbooks and referred to as reduction rhinoplasty. Most Asian hump noses have a small hump frequently associated with a low nasal dorsum and underprojection of the nasal tip. Correcting a hump nose in Asians has distinct differences in concept and technique. A small hump and additional need for augmentation of the dorsum and the tip often minimizes the amount of hump removal or obviates resection itself. Characteristics of the Asian hump nose with emphasis on surgical techniques commonly used to obtain reliable results are presented...
August 2018: Facial Plastic Surgery Clinics of North America
https://www.readbyqxmd.com/read/30005790/tip-grafting-for-the-asian-nose
#18
REVIEW
Yong Ju Jang, Sung Hee Kim
Tip surgery during rhinoplasty is particularly difficult in Asians. Tip grafting is the best approach. Conchal cartilage with perichondrium and costal cartilage are powerful grafting materials. The most important grafting techniques are tip-onlay grafting, shield grafting, and multilayer tip grafting. Tip-onlay grafts are useful for dorsal convexity. Shield grafts require sufficient support to prevent bending. Multilayer tip grafts (usually 2 layers) are versatile. Asians vary in cartilage configuration, skin thickness, and aesthetic desires: tip-grafting strategies must be tailored to meet the aesthetic goals of individuals...
August 2018: Facial Plastic Surgery Clinics of North America
https://www.readbyqxmd.com/read/30005789/septal-extension-graft-in-asian-rhinoplasty
#19
REVIEW
Na-Hyun Hwang, Eun-Sang Dhong
A septal extension graft (SEG) can control nasal tip projection, shape, and rotation. SEG and dorsal alloplastic implants have predominated in Asian rhinoplasty, leading to iatrogenic complications such as a foreshortened nose and destruction of remaining septum. The lower nasal two-thirds can be enhanced anteriorly and caudally using the septal L-strut extension graft in Asians with relatively small noses. The septal L-strut extension graft is indicated in primary cases in which the bony dorsum is acceptable but the cartilaginous dorsum is relatively hypoplastic, and in secondary cases with an iatrogenic short-nose deformity due to alloplastic implants...
August 2018: Facial Plastic Surgery Clinics of North America
https://www.readbyqxmd.com/read/30005788/injection-rhinoplasty-using-filler
#20
REVIEW
Hyoung Jin Moon
Rhinoplasty is a commonly performed cosmetic surgery in Asia. Rhinoplasty using filler is preferred because has fewer side effects and shorter down time. The part of external nose between the skin and bone or cartilages consists of 4 layers. To prevent vascular compromise, the injection should be into deep fatty layer, preventing embolization. Filler is usually injected in the order of radix, rhinion, tip, and the supratip area. To minimize asymmetry, the surgeon should always mark the midline on the nasal bridge and perform the procedure without deviating from it...
August 2018: Facial Plastic Surgery Clinics of North America
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