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Infectious Diseases in Obstetrics and Gynecology

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https://www.readbyqxmd.com/read/29731602/universal-rapid-human-immunodeficiency-virus-screening-at-delivery-a-cost-effectiveness-analysis
#1
Rachel K Scott, Stacia Crochet, Chun-Chih Huang
Objective: To determine the cost-effectiveness of universal maternal HIV screening at time of delivery to decrease mother-to-child transmission (MTCT), by comparing the cost and quality-adjusted life years (QALYs) of universal rapid HIV screening at time of delivery to two current standards of care for prenatal HIV screening in the United States. Study Design: We conducted a cost-effectiveness analysis to compare the cost and QALY of universal intrapartum rapid HIV screening with two current standards of care: (I) opt-out rapid HIV testing limited to patients without previous third-trimester screening and (II) opt-out rapid HIV testing limited to patients without any prenatal screening...
2018: Infectious Diseases in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29681727/time-kill-kinetics-of-rezafungin-cd101-in-vagina-simulative-medium-for-fluconazole-susceptible-and-fluconazole-resistant-candida-albicans-and-non-albicans-candida-species
#2
Jeffrey B Locke, Amanda L Almaguer, Joanna L Donatelli, Ken F Bartizal
Background: While echinocandins demonstrate excellent efficacy against Candida species in disseminated infections and demonstrate potent minimal inhibitory concentration (MIC) values under standard susceptibility testing conditions, investigation under conditions relevant to the vaginal environment was needed. We assessed the antifungal activity and time-kill kinetics of the novel echinocandin rezafungin (formerly CD101) under such conditions, against Candida species relevant to vulvovaginal candidiasis (VVC)...
2018: Infectious Diseases in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29348707/evolution-of-knowledge-awareness-and-practices-regarding-zika-virus-from-2016-to-2017
#3
Quinton Katler, Prachi Godiwala, Charles Macri, Beth Pineles, Gary Simon, Aileen Chang, Homa Ahmadzia
Objective: Our team created a knowledge, attitudes, and practice (KAP) survey in order to assess changes over time in healthcare provider and community member awareness of Zika virus symptoms, transmission, treatment, and current and future concerns. Study Design: The cross-sectional survey was issued at an academic medical center in Washington, DC, and via an online link to healthcare providers and community members between June and August 2016. Survey distribution was then repeated the following year, from March to April 2017...
2017: Infectious Diseases in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29259389/retracted-induction-of-heat-shock-protein-expression-in-cervical-epithelial-cells-by-human-semen
#4
Infectious Diseases In Obstetrics And Gynecology
[This retracts the article DOI: 10.1155/S1064744999000046.].
2017: Infectious Diseases in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29259388/genital-tract-infections-in-an-isolated-community-100-women-of-the-pr%C3%A3-ncipe-island
#5
Pedro Vieira-Baptista, Svitrigaile Grinceviciene, Gert Bellen, Carlos Sousa, Conceição Saldanha, Davy Vanden Broeck, John-Paul Bogers, Gilbert Donders
Objective: To characterize the vaginal microbiome and the rate of sexually transmitted infections (STIs) in the women of Príncipe (São Tomé and Príncipe). Methods: Cross-sectional study of 100 consecutive women, invited for a free appointment and cervical cancer screening. A vaginal slide (wet mount microscopy) and a cervical sample (ThinPrep®) (Pap test, high risk human papillomavirus [HR-HPV], N . gonorrhea [NG], T . vaginalis [TV], and C . trachomatis [CT]) were obtained...
2017: Infectious Diseases in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29180840/-candida-chorioamnionitis-leads-to-preterm-birth-and-adverse-fetal-neonatal-outcome
#6
REVIEW
Yohei Maki, Midori Fujisaki, Yuichiro Sato, Hiroshi Sameshima
Candida chorioamnionitis is rare but can lead to neonatal infection, high mortality, and neurodevelopmental impairment. We aimed to investigate maternal clinical features and perinatal outcomes and discuss future management strategies. We reviewed the medical records of women with Candida chorioamnionitis at our hospital over a 10-year period ( n = 9) and previous published case reports and case series. The most prevalent Candida species was C. albicans (71.3% of the all cases). The most prevalent predisposing condition was preterm premature rupture of membranes (31/123, 25...
2017: Infectious Diseases in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29104417/pubic-hair-shaving-is-correlated-to-vulvar-dysplasia-and-inflammation-a-case-control-study
#7
Meike Schild-Suhren, Amr A Soliman, Eduard Malik
Objective: The risk factors for vulvar dysplasia and infections are not fully known. In this study, we aimed to investigate the correlation between pubic hair shaving and the occurrence of vulvar inflammation, dysplasia, and cancer. Methods: This study was performed between January 2013 and December 2016 in which a standardized questionnaire concerning genital hair shaving was administered to vulvar dysplasia and cancer patients and healthy participants. The presence of human papilloma virus (HPV) infection and the occurrence of genital inflammation were documented...
2017: Infectious Diseases in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29075090/women-living-with-hiv-over-age-of-65-cervical-cancer-screening-in-a-unique-and-growing-population
#8
Alexandra Aserlind, Karla Maguire, Lunthita Duthely, Stefan Wennin, JoNell Potter
OBJECTIVE: Women living with HIV are at increased risk of human papillomavirus (HPV) infection, which can lead to cervical cancer. New guidelines recommend indefinite screening. The objective of this study is to describe cervical cancer screening practices and colposcopy results in a cohort of women living with HIV over age of 65 who were followed before the new guidelines. Comorbidities, sexually transmitted infections (STIs), and other risk factors were evaluated. METHODS: We conducted a retrospective chart review on 75 women aged 65 or older living with HIV with at least one Pap smear...
2017: Infectious Diseases in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28831237/knowledge-of-human-cytomegalovirus-infection-and-prevention-in-pregnant-women-a-baseline-operational-survey
#9
Maria Mazzitelli, Mariella Micieli, Carmela Votino, Federica Visconti, Paola Quaresima, Alessio Strazzulla, Carlo Torti, Fulvio Zullo
Currently, the only efficient way to prevent human Cytomegalovirus (HCMV) infection in pregnancy is primary prophylaxis through hygienic measures. So, we evaluated knowledge of HCMV and its prevention in a group of pregnant women. An anonymous questionnaire with multiple-choice answers was administered to all pregnant women who were followed up at the Obstetrics and Gynecology Unit of "Pugliese-Ciaccio Hospital," a third-level hospital in Catanzaro (Southern Italy), from November 2015 to March 2016...
2017: Infectious Diseases in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28804240/dual-method-use-among-postpartum-hiv-infected-and-hiv-uninfected-malawian-women-a-prospective-cohort-study
#10
Dawn M Kopp, Jennifer H Tang, Gretchen S Stuart, William C Miller, Michele S O'Shea, Mina C Hosseinipour, Phylos Bonongwe, Mwawi Mwale, Nora E Rosenberg
Dual method use, use of condoms plus another effective contraceptive method, is important in settings with high rates of unintended pregnancy and HIV infection. We evaluated the association of HIV status with dual method use in a cohort of postpartum women. Women completed baseline surveys in the postpartum ward and telephone surveys about contraceptive use 3, 6, and 12 months later. Nonpregnant women who completed at least one follow-up survey were eligible for this secondary analysis. Prevalence ratios were calculated using generalized estimating equations...
2017: Infectious Diseases in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28717342/prevalence-of-high-risk-genotypes-of-human-papillomavirus-women-diagnosed-with-premalignant-and-malignant-pap-smear-tests-in-southern-ecuador
#11
Paola Dalgo Aguilar, Cisne Loján González, Ana Córdova Rodríguez, Katherine Acurio Páez, Ana Paulina Arévalo, Jana Bobokova
Human papillomavirus (HPV) is the primary infectious agent for the development of cervical cancer, although the presence of the virus alone is insufficient for viral development and proliferation; this can be attributed to the increase in potential oncogenic risk, along with other risk factors. In the present investigation, the prevalence of high-risk HPV was determined from samples of premalignant or malignant cervical cytology in women from the southern region of Ecuador. The kit we used was able to detect genotypes 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, and 59...
2017: Infectious Diseases in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28408795/epidemiology-and-molecular-typing-of-pregnancy-associated-listeriosis-cases-in-lombardy-italy-over-a-10-year-period-2005-2014
#12
Virginia Filipello, Ettore Amato, Maria Gori, Pol Huedo, Giulia Ciceri, Sara Lomonaco, Mirella Pontello
In developed countries, pregnancy-related listeriosis accounts for 20-43% of total invasive listeriosis. This work describes the first pregnancy-related listeriosis survey in Italy based on two data sources, that is, mandatory notification system and regional laboratory-based network. Out of 610 listeriosis cases reported over a 10-year period, 40 were pregnancy-related (6.6%). Among these, 29 pregnancy-related isolates were available and have been analysed with serotyping, Pulsed-Field Gel Electrophoresis, and Multi-Virulence-Locus Sequence Typing...
2017: Infectious Diseases in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28325959/perinatal-mortality-associated-with-positive-postmortem-cultures-for-common-oral-flora
#13
Mai He, Alison R Migliori, Patricia Lauro, C James Sung, Halit Pinar
Introduction . To investigate whether maternal oral flora might be involved in intrauterine infection and subsequent stillbirth or neonatal death and could therefore be detected in fetal and neonatal postmortem bacterial cultures. Methods . This retrospective study of postmortem examinations from 1/1/2000 to 12/31/2010 was searched for bacterial cultures positive for common oral flora from heart blood or lung tissue. Maternal age, gestational age, age at neonatal death, and placental and fetal/neonatal histopathological findings were collected...
2017: Infectious Diseases in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28293099/a-comparison-of-colorimetric-assessment-of-vaginal-ph-with-nugent-score-for-the-detection-of-bacterial-vaginosis
#14
RANDOMIZED CONTROLLED TRIAL
Matthew K Hoffman, Mrutyunjaya B Bellad, Umesh S Charantimath, Avinash Kavi, Jyoti M Nagmoti, Mahantesh B Nagmoti, Ashalata A Mallapur, Geetanjali M Katageri, Umesh Y Ramadurg, Sheshidhar G Bannale, Amit P Revankar, M S Ganachari, Richard J Derman, Shivaprasad S Goudar
Background . A Nugent score > 7 has been defined as the gold standard for the diagnosis for bacterial vaginosis (BV), though it is resource intensive and impractical as point of care testing. We sought to determine if colorimetric assessment of vaginal pH can accurately predict the occurrence of BV. Methods . We performed a planned subanalysis of 1,216 pregnant women between 13 0/7 and 19 6/7 weeks who underwent vaginal examination as part of a randomized controlled trial. Using a standardized technique, specimens were obtained for colorimetric assessment and two separate slides for Gram staining...
2017: Infectious Diseases in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28280293/cervicovaginal-bacteriology-and-antibiotic-sensitivity-patterns-among-women-with-premature-rupture-of-membranes-in-mulago-hospital-kampala-uganda-a-cross-sectional-study
#15
Milton W Musaba, Mike N Kagawa, Charles Kiggundu, Paul Kiondo, Julius Wandabwa
Background . A 2013 Cochrane review concluded that the choice of antibiotics for prophylaxis in PROM is not clear. In Uganda, a combination of oral erythromycin and amoxicillin is the 1st line for prophylaxis against ascending infection. Our aim was to establish the current cervicovaginal bacteriology and antibiotic sensitivity patterns. Methods . Liquor was collected aseptically from the endocervical canal and pool in the posterior fornix of the vagina using a pipette. Aerobic cultures were performed on blood, chocolate, and MacConkey agar and incubated at 35-37°C for 24-48 hrs...
2017: Infectious Diseases in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28260847/effect-of-genital-sampling-site-on-the-detection-and-quantification-of-ureaplasma-species-with-quantitative-polymerase-chain-reaction-during-pregnancy
#16
Gilles Faron, Ellen Vancutsem, Anne Naessens, Ronald Buyl, Leonardo Gucciardo, Walter Foulon
Objective . This study aimed to compare the qualitative and quantitative reproducibility of quantitative PCR (qPCR) for Ureaplasma species (Ureaplasma spp.) throughout pregnancy and according to the genital sampling site. Study Design . Between 5 and 14 weeks of gestation (T1), vaginal, fornix, and two cervical samples were taken. Sampling was repeated during the 2nd (T2) and 3rd (T3) trimester in randomly selected T1 positive and negative women. Qualitative and quantitative reproducibility were evaluated using, respectively, Cohen's kappa ( κ ) and interclass correlation coefficients (ICC) and repeated measures ANOVA on the log-transformed mean number of DNA copies for each sampling site...
2017: Infectious Diseases in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27872553/development-of-a-novel-test-for-simultaneous-bacterial-identification-and-antibiotic-susceptibility
#17
Jonathan Faro, Malika Mitchell, Yuh-Jue Chen, Sarah Kamal, Gerald Riddle, Sebastian Faro
Background. Elucidation of a pathogen's antimicrobial susceptibility requires subculture after the organism is first isolated. This takes several days, requiring patients to be treated with broad-spectrum antibiotics. This approach contributes to the development of bacterial resistance. Methods. Microtiter wells were coated with a polyclonal antibody targeting the pathogen of interest. Bacterial suspensions were added in the presence/absence of selected antibiotics. After washing, captured bacteria were detected...
2016: Infectious Diseases in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27829780/bacterial-load-in-daily-urine-samples-of-patients-infected-with-mycoplasma-genitalium-mutation-analysis-and-response-to-treatment
#18
M Gossé, S A Nordbø, B Pukstad
Objective. Increasing macrolide resistant strains of Mycoplasma genitalium is a challenge, and to differentiate between treatment failure and reinfection a timely test of cure (TOC) is warranted. The aim of this study was to evaluate the best time for TOC after five days' treatment of Mycoplasma genitalium infection with azithromycin. Methods. Nineteen patients with positive PCR for Mycoplasma genitalium in urine provided urine samples daily for 2 weeks and on days 21, 28, and 35. Samples were tested by a commercial qPCR and by sequencing of the 23S rRNA gene...
2016: Infectious Diseases in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27672303/prevalence-of-chlamydia-trachomatis-among-childbearing-age-women-in-india-a-systematic-review
#19
REVIEW
Kalpana Betha, Jamie M Robertson, Gong Tang, Catherine L Haggerty
Background. Infection with Chlamydia trachomatis (CT) can lead to reproductive sequelae. Information on the general population of childbearing age women in India is sparse. We reviewed the literature on CT prevalence within the general population of reproductive aged women in order to improve the efforts of public health screening programs and interventions. Objective. To conduct a literature review to determine the prevalence of Chlamydia trachomatis among childbearing age women in India. Search Strategy. Ovid Medline and PubMed databases were searched for articles from January 1, 2003, through December 31, 2014...
2016: Infectious Diseases in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27642245/factors-associated-with-hormonal-and-intrauterine-contraceptive-use-among-hiv-infected-men-and-women-in-lilongwe-malawi-a-cross-sectional-study
#20
Jennifer H Tang, Sam Phiri, Wingston Ng'ambi, Jamie W Krashin, Linly Mlundira, Thom Chaweza, Bernadette Samala, Hannock Tweya, Mina C Hosseinipour, Lisa B Haddad
Background. Understanding the factors associated with the use of hormonal and intrauterine contraception among HIV-infected men and women may lead to interventions that can help reduce high unintended pregnancy rates. Materials and Methods. This study is a subanalysis of a cross-sectional survey of 289 women and 241 men who were sexually active and HIV-infected and were attending HIV care visits in Lilongwe, Malawi. We estimated adjusted prevalence ratios (PRs) to evaluate factors associated with hormonal and intrauterine contraceptive use for men and women in separate models...
2016: Infectious Diseases in Obstetrics and Gynecology
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