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Journal of Environmental Science and Health. Part C, Environmental Carcinogenesis & Ecotoxicology Reviews

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https://www.readbyqxmd.com/read/29336723/chemical-characterization-and-evaluation-of-the-antioxidants-in-chaenomeles-fruits-by-an-improved-hplc-tof-ms-coupled-to-an-on-line-dpph-hplc-method
#1
Minmin Zhang, Ruixuan Zhao, Siduo Zhou, Wei Liu, Yan Liang, Zhiguo Zhao, Shengbo Li, Xiao Wang, Tityee Wong, Hengqiang Zhao
An improved method based on HPLC-TOF/MS was developed to catalog the antioxidants in five species of Chaenomeles (Mugua). Forty-four fractions from the Mugua extracts show appreciable levels of antioxidative activity in scavenging the stable free-radical 2,2-diphenyl-1-picrylhydrazyl and the hydroxyl radicals. Twelve major antioxidant's chemical structures are identified. Antioxidant activities differ between species, but intra-species level of antioxidants, regardless of their ripeness, are similar. C. sinensis has the highest antioxidant level...
January 16, 2018: Journal of Environmental Science and Health. Part C, Environmental Carcinogenesis & Ecotoxicology Reviews
https://www.readbyqxmd.com/read/29313413/nanoparticles-considered-as-mixtures-for-toxicological-research
#2
Hua Deng, Ying Zhang, Hongtao Yu
Nanoparticles are used widely in our lives, but the understanding of their impacts on human and environmental health is still limited, at least due in part to the fact that nanoparticles are mixtures. This review describes that "nanotoxicity" is actually a test of the overall effect of a nanoparticle mixture: starting materials for nanoparticle preparation, surface coating agents, surface reaction-generated species, and transformed byproducts of the nanoparticle in biological and environmental media, as well as variations of the intrinsic nanoparticle structures...
January 9, 2018: Journal of Environmental Science and Health. Part C, Environmental Carcinogenesis & Ecotoxicology Reviews
https://www.readbyqxmd.com/read/29297743/toxicity-of-engineered-nanomaterials-mediated-by-nano-bio-eco-interactions
#3
Xiaojia He, Peter Fu, Winfred G Aker, Huey-Min Hwang
Engineered nanomaterials may adversely impact human health and environmental safety by nano-bio-eco interactions not fully understood. Their interaction with biotic and abiotic environments are varied and complicated, ranging from individual species to entire ecosystems. Their behavior, transport, fate, and toxicological profiles in these interactions, addressed in a pioneering study, are subsequently seldom reported. Biological, chemical, and physical dimension properties, the so-called multidimensional characterization, determine interactions...
January 3, 2018: Journal of Environmental Science and Health. Part C, Environmental Carcinogenesis & Ecotoxicology Reviews
https://www.readbyqxmd.com/read/29115913/exploring-the-activities-of-ruthenium-nanomaterials-as-reactive-oxygen-species-scavengers
#4
Gao-Juan Cao, Xiumei Jiang, Hui Zhang, Jiwen Zheng, Timothy R Croleyband Jun-Jie Yin
Research on noble metal nanoparticles able to scavenge reactive oxygen species (ROS) has undergone a tremendous growth recently. However, the interactions between ruthenium nanoparticles (Ru NPs) and ROS have never been systematically explored thus far. This research focused on the decomposition of H2O2, scavenging of (•)OH, O2(•-), (1)O2, ABTS(•+) and (•)DPPH in presence of commercial Ru NPs using the ESR technique. In vitro cell studies demonstrated that Ru NPs have excellent biocompatibility and exert a cytoprotective effect against oxidative stress...
November 8, 2017: Journal of Environmental Science and Health. Part C, Environmental Carcinogenesis & Ecotoxicology Reviews
https://www.readbyqxmd.com/read/29106334/effects-of-chronic-alcohol-consumption-on-dna-damage-and-immune-regulation-induced-by-the-environmental-pollutant-dibenzo-a-l-pyrene-in-oral-tissues-of-mice
#5
Kun-Ming Chen, Todd D Schell, John P Richie, Yuan-Wan Sun, Shang-Min Zhang, Ana Calcagnotto, Cesar Aliga, Krishne Gowda, Shantu Amin, Karam El-Bayoumy
Previously, we showed that oral application of the environmental pollutant dibenzo[a,l]pyrene (DB[a,l]P) induces oral tumors in mice. Thus, in the present investigation we examined the effect of alcohol on DB[a,l]P-induced DNA damage and immune regulation; we showed that alcohol (6.4% v/v in the diet, 35% of Calories) significantly enhanced the levels of (-)-anti-trans-DB[a,l]P-dA while decreased the levels of GSH in the mouse oral tissues. Analysis of RNA expression revealed that DB[a,l]P alone upregulates inflammatory genes while alcohol suppresses several markers of immune surveillance...
November 6, 2017: Journal of Environmental Science and Health. Part C, Environmental Carcinogenesis & Ecotoxicology Reviews
https://www.readbyqxmd.com/read/29040049/recent-trends-in-common-chemical-feed-and-food-contaminants-in-israel
#6
J A Shimshoni, Y Chen, E Sobol, I Maz, S Barel
In February 2014 a new law was approved by the Israeli parliament, namely the Control of Animal Feed Law. The law intends to regulate the production and marketing of animal feed. In preparation for the law's implementation in 2017, we have assessed the current feed and food safety challenges in Israel in recent years in association with the presence of common undesirable contaminants in various common feed and food commodities. Tight collaboration between regulatory authorities and fee/food industry, enhanced feed and food quality monitoring, transparency of survey results and readily accessible and reliable information for the public about health hazards of chemical contaminants, will guarantee the safety and quality of food and feed...
October 17, 2017: Journal of Environmental Science and Health. Part C, Environmental Carcinogenesis & Ecotoxicology Reviews
https://www.readbyqxmd.com/read/29027864/integrating-computational-methods-to-predict-mutagenicity-of-aromatic-azo-compounds
#7
Domenico Gadaleta, Nicola Porta, Eleni Vrontaki, Serena Manganelli, Alberto Manganaro, Guido Sello, Masamitsu Honma, Emilio Benfenati
Azo dyes have several industrial uses. However, these azo dyes and their degradation products showed mutagenicity, inducing damage in environmental and human systems. Computational methods are proposed as cheap and rapid alternatives to predict the toxicity of azo dyes. A benchmark dataset of Ames data for 354 azo dyes was employed to develop three classification strategies using knowledge-based methods and docking simulations. Results were compared and integrated with three models from the literature, developing a series of consensus strategies...
October 13, 2017: Journal of Environmental Science and Health. Part C, Environmental Carcinogenesis & Ecotoxicology Reviews
https://www.readbyqxmd.com/read/29236591/editorial-board-page-eov
#8
(no author information available yet)
No abstract text is available yet for this article.
October 2, 2017: Journal of Environmental Science and Health. Part C, Environmental Carcinogenesis & Ecotoxicology Reviews
https://www.readbyqxmd.com/read/28581903/a-decision-tree-approach-to-screen-drinking-water-contaminants-for-multiroute-exposure-potential-in-developing-guideline-values
#9
Kannan Krishnan, Richard Carrier
The consideration of inhalation and dermal routes of exposures in developing guideline values for drinking water contaminants is important. However, there is no guidance for determining the eligibility of a drinking water contaminant for its multiroute exposure potential. The objective of the present study was to develop a 4-step framework to screen chemicals for their dermal and inhalation exposure potential in the process of developing guideline values. The proposed framework emphasizes the importance of considering basic physiochemical properties prior to detailed assessment of dermal and inhalation routes of exposure to drinking water contaminants in setting guideline values...
June 5, 2017: Journal of Environmental Science and Health. Part C, Environmental Carcinogenesis & Ecotoxicology Reviews
https://www.readbyqxmd.com/read/28532274/formation-of-iron-oxide-pd-hybrid-nanostructures-with-enhanced-peroxidase-like-activity-and-catalytic-reduction-of-4-nitrophenol
#10
Jing Li, Junhui Cai, Huimin Jia, Lixia Zhang, Yan Lei, Weiwei He, Jun-Jie Yin
Iron oxide/Pd hybrid nanostructures with controllable Pd loading from 0.05 to 1.0 (calculated as Pd/Fe molar ratio) have been synthesized by chemical reduction of Pd(2+) on iron oxide particles. The combination of iron oxide and Pd exhibits enhanced peroxidase-like activity and catalytic activity toward reduction of 4-nitrophenol. The catalytic enhancements were found to be dependent on the Pd loading amount as well as the synergistic effect between iron oxide and Pd. These results suggest that iron oxide with unique surface chemical state can be an active supporter and suggest an effective way to design superior hybrid nanostructures for catalytic applications...
May 22, 2017: Journal of Environmental Science and Health. Part C, Environmental Carcinogenesis & Ecotoxicology Reviews
https://www.readbyqxmd.com/read/28506110/evaluation-of-chemical-mutagenicity-using-next-generation-sequencing-a-review
#11
Hua Du, Bohu Pan, Tao Chen
Mutations are heritable changes in the nucleotide sequence of DNA that can lead to many adverse effects. Genotoxicity assays have been used to identify chemical mutagenicity. Recently, next generation sequencing (NGS) has been used for this purpose. In this review, we present the progress in NGS application for assessing mutagenicity of chemicals, including the methods used for detecting the induced mutations, bioinformatics tools for analyzing the sequencing data, and chemicals whose mutagenicity has been evaluated using NGS...
May 16, 2017: Journal of Environmental Science and Health. Part C, Environmental Carcinogenesis & Ecotoxicology Reviews
https://www.readbyqxmd.com/read/28506107/immunoassay-approach-for-diagnosis-of-exposure-to-pyrrolizidine-alkaloids
#12
Na Li, Fan Zhang, Wei Lian, Huali Wang, Jiang Zheng, Ge Lin
Numerous pyrrolizidine alkaloid (PA) poisoning cases have been documented worldwide. Protein covalent binding with reactive metabolites generated from metabolic activation of PAs to form pyrrole-protein adducts is suggested to be a primary mechanism of PA-induced toxicities. The present study aimed to develop antibodies for diagnosis of PA exposure. Polyclonal antibodies were raised in rabbits and proven to specifically recognize pyrrole-protein adducts regardless of amino acid residues modified by the reactive metabolites of PAs...
May 16, 2017: Journal of Environmental Science and Health. Part C, Environmental Carcinogenesis & Ecotoxicology Reviews
https://www.readbyqxmd.com/read/28481723/key-challenges-for-nanotechnology-standardization-of-ecotoxicity-testing
#13
REVIEW
Cristina Cerrillo, Gotzone Barandika, Amaya Igartua, Olatz Areitioaurtena, Gemma Mendoza
Nanotechnology is expected to contribute to the protection of the environment, but many uncertainties exist regarding the environmental and human implications of manufactured nanomaterials (MNMs). Contradictory results have been reported for their ecotoxicity to aquatic organisms, which constitute one of the most important pathways for their entrance and transfer throughout the food web. The present review is focused on the international strategies that are laying the foundations of the ecotoxicological assessment of MNMs...
April 3, 2017: Journal of Environmental Science and Health. Part C, Environmental Carcinogenesis & Ecotoxicology Reviews
https://www.readbyqxmd.com/read/28418776/7-glutathione-pyrrole-and-7-cysteine-pyrrole-are-potential-carcinogenic-metabolites-of-pyrrolizidine-alkaloids
#14
Xiaobo He, Qingsu Xia, Peter P Fu
Many pyrrolizidine alkaloids (PAs) are hepatotoxic, genotoxic, and carcinogenic phytochemicals. Metabolism of PAs in vivo generates four (±)-6,7-dihydro-7-hydroxy-1-hydroxymethyl-5H-pyrrolizine (DHP)-DNA adducts that have been proposed to be responsible for PA-induced liver tumor formation in rats. In this present study, we determined that the same set of DHP-DNA adducts was formed upon the incubation of 7-glutathione-DHP and 7-cysteine-DHP with cultured human hepatocarcinoma HepG2 cells. These results suggest that 7-glutathione-DHP and 7-cysteine-DHP are reactive metabolites of PAs that can bind to cellular DNA to form DHP-DNA adducts in HepG2 cells, and can potentially initiate liver tumor formation...
April 3, 2017: Journal of Environmental Science and Health. Part C, Environmental Carcinogenesis & Ecotoxicology Reviews
https://www.readbyqxmd.com/read/28418774/arsenic-in-the-groundwater-occurrence-toxicological-activities-and-remedies
#15
REVIEW
S K Jha, V K Mishra, T Damodaran, D K Sharma, Parveen Kumar
Arsenic (As) contamination in groundwater has become a geo-environmental as well as a toxicological problem across the globe affecting more than 100-million people in nearly 21 countries with its associated disease "arsenicosis." Arsenic poisoning may lead to fatal skin and internal cancers. In present review, an attempt has been made to generate awareness among the readers about various sources of occurrence of arsenic, its geochemistry and speciation, mobilization, metabolism, genotoxicity, and toxicological exposure on humans...
April 3, 2017: Journal of Environmental Science and Health. Part C, Environmental Carcinogenesis & Ecotoxicology Reviews
https://www.readbyqxmd.com/read/28222272/corrigendum
#16
(no author information available yet)
No abstract text is available yet for this article.
January 2, 2017: Journal of Environmental Science and Health. Part C, Environmental Carcinogenesis & Ecotoxicology Reviews
https://www.readbyqxmd.com/read/28095116/recent-progress-on-the-development-of-anisotropic-gold-nanoparticles-design-strategies-and-growth-mechanism
#17
REVIEW
Stacy Jones, Avijit Pramanik, Carrie Sweet, Anthony Keyes, Salma Begum, Aruna Vangra, Hongtal Yu, Peter P Fu, Paresh Chandra Ray
This review summarizes recent advances on design strategies for shape-controlled anisotropic gold nanoparticles. Detailed chemical mechanism has been discussed to understand the anisotropic growth. The effect of various chemical parameters and surface facets for the formation of different shaped anisotropic nanoparticles have been addressed.
January 2, 2017: Journal of Environmental Science and Health. Part C, Environmental Carcinogenesis & Ecotoxicology Reviews
https://www.readbyqxmd.com/read/28055331/review-of-ginkgo-biloba-induced-toxicity-from-experimental-studies-to-human-case-reports
#18
REVIEW
Nan Mei, Xiaoqing Guo, Zhen Ren, Daisuke Kobayashi, Keiji Wada, Lei Guo
Ginkgo biloba seeds and leaves have been used as a traditional herbal remedy for thousands of years, and its leaf extract has been consumed as a botanical dietary supplement for decades. Ginkgo biloba extract is a complex mixture with numerous components, including flavonol glycosides and terpene lactones, and is one of the most widely sold botanical dietary supplements worldwide. Concerns about potential health risks for the general population have been raised because of the widespread human exposure to Ginkgo biloba and its potential toxic and carcinogenic activities in rodents...
January 2, 2017: Journal of Environmental Science and Health. Part C, Environmental Carcinogenesis & Ecotoxicology Reviews
https://www.readbyqxmd.com/read/28055311/immunotoxicity-of-mercury-pathological-and-toxicological-effects
#19
REVIEW
Faheem Maqbool, Kamal Niaz, Fatima Ismail Hassan, Fazlullah Khan, Mohammad Abdollahi
Mercury (Hg) is toxic and hazardous metal that causes natural disasters in the earth's crust. Exposure to Hg occurs via various routes; like oral (fish), inhalation, dental amalgams, and skin from cosmetics. In this review, we have discussed the sources of Hg and its potential for causing toxicity in humans. In addition, we also review its bio-chemical cycling in the environment; its systemic, immunotoxic, genotoxic/carcinogenic, and teratogenic health effects; and the dietary influences; as well as the important considerations in risk assessment and management of Hg poisoning have been discussed in detail...
January 2, 2017: Journal of Environmental Science and Health. Part C, Environmental Carcinogenesis & Ecotoxicology Reviews
https://www.readbyqxmd.com/read/27901648/a-new-drug-design-strategy-killing-drug-resistant-bacteria-by-deactivating-their-hypothetical-genes
#20
Tit-Yee Wong, Jimmy Kuo
Despite that a bacterial genome is complicated by large numbers of horizontally transferred (HT) genes and function unknown hypothetical (FUN) genes, the Genic-Transcriptional-Stop-Signals-Ratio (TSSR) of a genome shows that HT and FUN genes are complementary to all other genes in the genome. When HT or certain FUN genes are omitted from the Escherichia coli K-12 genome, its Genomic-TSSR value becomes totally incomparable to other E. coli strains. The Genic-TSSR correlation tree of a pathogen shows that some FUN genes would form a unique cluster...
October 2016: Journal of Environmental Science and Health. Part C, Environmental Carcinogenesis & Ecotoxicology Reviews
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