Read by QxMD icon Read

Colloids and Surfaces. B, Biointerfaces

Pengbo Ning, Zhongxing Wu, Xuepeng Li, Yulu Zhou, Aoxue Hu, Xiaocheng Gong, Jun He, Yuqiong Xia, Kangkang Guo, Ruili Zhang, Xianghan Zhang, Zhongliang Wang
Classical swine fever (CSF) is a devastating viral disease affecting pigs that causes major economic losses worldwide. Conventional assays to identify classical swine fever virus (CSFV) face challenges, such as the required molecular amplification of the target molecules via polymerase chain reaction (PCR). We designed a gold nanoflare probe to directly detect CSFV. Gold nanoparticles (AuNPs) were conjugated with a pair of complementary DNA sequences that specifically recognized and captured CSFV RNA, resulting in a fluorescence signal to indicate the existence of CSFV...
July 11, 2018: Colloids and Surfaces. B, Biointerfaces
Siva Bala Subramaniyan, Anugraha Ramani, V Ganapathy, Veerappan Anbazhagan
In this work, phytoprotein functionalized platinum nanoparticles (PtNCs) were synthesized using the proteins from fresh green spinach leaves. Transmission electron microscopy showed that PtNCs were spherical shape with size ∼5 nm, which self assembled into spherical platinum nanoclustures (PtNCs) with size within the range of 100-250 nm. The presence of elemental platinum was confirmed by EDX analysis. FTIR studies confirm that the PtNCs were stabilized by the protein. As prepared PtNCs inhibits the growth of the food borne pathogen, Salmonella typhi with minimum inhibitory concentration (MIC) of 12...
July 11, 2018: Colloids and Surfaces. B, Biointerfaces
Xiyu Ding, Yanmei Zhang, Jinyan Ling, Changjian Lin
Mussel-inspired deposition of polydopamine (PDA) is a green chemical method that has been used to load silver nanoparticles on titanium oxide nanotubes (TiO2 NTs) to kill bacteria. However, a long reaction time is required for both the polymerization of dopamine and the reaction between PDA and silver nitrate. In addition, the deposition of silver nanoparticles is difficult to control, which may increase the risk of cytotoxicity. In this study, a rapid polymerization of dopamine was achieved by performing the reaction in a water bath at 90 °C (PDA-H)...
July 9, 2018: Colloids and Surfaces. B, Biointerfaces
Laís C Brazaca, Camila B Bramorski, Juliana Cancino-Bernardi, Sanseray da Silveira Cruz-Machado, Regina P Markus, Bruno C Janegitz, Valtencir Zucolotto
Melatonin, the 'chemical signal of darkness', is responsible to regulate biological rhythms and different physiological processes. It is mainly produced by the pineal gland as a hormone in a rhythmic daily basis, but it may also be synthesized by other tissues, such as immune cells, under inflammatory conditions. Its abnormal circulating levels have been related to several diseases such as type 2 diabetes, Alzheimer's disease and some types of cancer. Currently, melatonin is exclusively quantified by ELISA or radioimmunoassays, which although are very sensitive techniques and present low detection limits, usually require specialized personal and equipment, restricting the tests to a limited number of patients...
July 7, 2018: Colloids and Surfaces. B, Biointerfaces
Zar Chi Soe, Raj Kumar Thapa, Wenquan Ou, Milan Gautam, Hanh Thuy Nguyen, Sung Giu Jin, Sae Kwang Ku, Kyung Taek Oh, Han-Gon Choi, Chul Soon Yong, Jong Oh Kim
Drug targeting using functionalized nanoparticles provides a new standard in anticancer therapy. Liposomes, safe and effective drug delivery carriers, can incorporate both hydrophilic and hydrophobic drugs for combination chemotherapy treatment of cancers. The objectives of the current study were to synthesize and test the effectiveness of a nanotechnology-based strategy utilizing folic acid (FA)-conjugated liposomes that incorporate both celastrol (Cs) and irinotecan (Ir) for targeted breast cancer therapy...
July 7, 2018: Colloids and Surfaces. B, Biointerfaces
Elisabetta Esposito, Federica Carducci, Paolo Mariani, Nicolas Huang, Fanny Simelière, Rita Cortesi, Giuseppe Romeo, Carmelo Puglia
The present investigation concerns the production and characterization of monoolein-water systems designed for cutaneous administration of crocetin. The different monoolein crystalline phases forming in the presence of crocetin as a function of added water have been investigated by x-ray and polarized light microscopy. Franz cell was employed to compare in vitro the crocetin diffusion from selected monoolein water systems containing 95, 90 or 75% w/w of monoolein, while to investigate the performance of monoolein-water as transdermal delivery systems, in vivo studies, based on tape stripping were performed...
July 6, 2018: Colloids and Surfaces. B, Biointerfaces
Anna Pawlik, Robert P Socha, Marie Hubalek Kalbacova, Grzegorz D Sulka
Nowadays, titanium and its alloys are the most commonly used implantable materials. The surface topography and chemistry of titanium-based implants are responsible for osseointegration. One of the methods to improve biocompatibility of Ti implants is a modification with sodium hydroxide (NaOH) or 3-aminopropyltriethoxysilane (APTES). In the present study, anodic titanium dioxide (ATO) layers were electrochemically fabricated, and then immersed in a NaOH solution or in NaOH and APTES solutions. The functionalized samples were characterized by using scanning electron microscopy (SEM) and X-ray photoelectron spectroscopy (XPS)...
July 6, 2018: Colloids and Surfaces. B, Biointerfaces
Tao Xu, Qingqing Yao, Jacob M Miszuk, Hanna J Sanyour, Zhongkui Hong, Hongli Sun, Hao Fong
Three-dimensional (3D) scaffolds as artificial ECMs have been extensively studied to mimic the critical features of natural ECMs. To develop more clinically relevant 3D scaffolds, electrospun nanofibrous scaffolds with different weight ratios of PCL/PLA (i.e., 100/0, 60/40, and 20/80) were fabricated via the thermally induced (nanofiber) self-agglomeration (TISA) method. The hypothesis was that, with the weight ratio increase of stiffer and more bioactive PLA in the 3D PCL/PLA blend scaffolds, the osteogenic differentiation of human mesenchymal stem cells (hMSCs) would be enhanced...
July 6, 2018: Colloids and Surfaces. B, Biointerfaces
Cheng Zhou, Jianqiong Huang, Qian Yang, Tao Li, Jin Liu, Zhiyong Qian
Long-lasting regional anesthesia and selective sensory block are useful in post-operative analgesia and treatment of pathological pain. Previous studies have demonstrated that activation of TRPV1 (Transient Receptor Potential Vanilloid Type-1) channels facilitated the potency of QX-314 for selective long-lasting regional anesthesia in vivo. Hydrogel is a solid jelly-like material covering a wide range of properties from soft and weak to hard and tough. Gold nanorods are nanoparticles, which can be used for hyperthermia by exposure to near-infrared radiation...
July 6, 2018: Colloids and Surfaces. B, Biointerfaces
Lei Xu, Xiao-Yan He, Bo-Ya Liu, Chang Xu, Shu-Lun Ai, Ren-Xi Zhuo, Si-Xue Cheng
Proteins have been extensively explored as versatile nanocarriers for drug delivery due to their complete biocompatibility, ease of surface modification, and lack of toxicity and immunogenicity. In this study, a facile strategy was used to construct aptamer-functionalized albumin-based nanoparticles for effective drug delivery and targeted cancer therapy. A hydrophobic drug, doxorubicin (DOX) was employed to trigger the self-assembly of bovine serum albumin (BSA) to from stable nanoparticles via hydrophobic interaction, and then a tumor targeting aptamer AS1411 was incorporated to the surface of DOX loaded BSA...
July 5, 2018: Colloids and Surfaces. B, Biointerfaces
Rezaei Farnaz, Saeidifar Maryam, Javaheri Masoumeh, Sangpour Parvaneh
A novel sustained release carrier of graphene oxide nanosheets functionalized by human serum albumin nanoparticles (FGO-NSs) was synthesized and characterized by field emission scanning electron microscopy (FESEM), zeta sizer analysis, absorption spectroscopy (UV-vis) and Fourier transform infrared spectroscopy (FTIR) studies. The cell viability of GO-NSs, HSA-NPs and FGO-NSs has been tested against human foreskin fibroblast normal cell line, HFFF2 by MTT assay technique. Loading efficiency and release properties of oxaliplatin (OX), as an effective chemotherapeutic agent in the treatment of cancers, from HSA-NPs and FGO-NSs were studied...
July 5, 2018: Colloids and Surfaces. B, Biointerfaces
Wen-Yi Qiu, Yao-Yao Wang, Meng Wang, Jing-Kun Yan
Selenium nanoparticles (SeNPs) as a new replacement source of other Se forms applied in nutritional supplements have been associated with health-related issues. Pectin (PEC) as a well-known food-grade polysaccharide has been considered as a potential soft template for the preparation and stabilization of SeNPs in aqueous medium. In this study, therefore, PEC was used as a stabilizer and dispersing agent to form well-dispersed and stable SeNPs under a simple redox system of selenite and ascorbic acid. Se/PEC ratios significantly affected the color of the suspension, particle size, and surface morphology of the as-prepared SeNPs in the presence of PEC...
July 5, 2018: Colloids and Surfaces. B, Biointerfaces
Sachin Rathod, Rahul Tripathi, Gunjan Verma, Vinod K Aswal, Pratap Bahadur, Sanjay Tiwari
Carbamazepine (CBZ) shows inconsistent absorption primarily due to its poor dissolution rate. In this study, we describe a bioadhesive polymeric film, embedded with microemulsion (ME), as a tool to enable improved CBZ dissolution and achieve sustained release. The ME was formulated using pseudo-ternary components; water, oil (n-butyl acetate), surfactant (tocopheryl polyethylene glycol 1000 succinate, TPGS) and cosurfactant (1,4-butanediol). The region at surfactant to co-surfactant ratio of 1:1 was characterized using dynamic light scattering, small angle neutron scattering and differential scanning calorimetry...
July 5, 2018: Colloids and Surfaces. B, Biointerfaces
Raïssa A R Teixeira, Alexandre A B Lataliza, Nádia R B Raposo, Luiz Antônio S Costa, Antônio Carlos Sant'Ana
Gold nanoparticles (AuNP) were synthesized and modified with anti-folate receptor antibody (AB), folic acid (FA), crystal violet (CV), poly (ethyleneglycol) methyl ether thiol and the antineoplastic drug tamoxifen (TAM). Such a preparation was incubated in vitro with MCF-7 human breast cancer cells, showing a decrease in the TAM dosage for the reduction of cell viability. The adsorption of TAM on gold surface was investigated by surface-enhanced Raman scattering (SERS) spectroscopy and the assignment based on Density Functional Theory calculations showed that the ether moiety was involved in the interactions with the metal...
July 4, 2018: Colloids and Surfaces. B, Biointerfaces
Jiaojiao Liu, Bin Song, Jingliang Li, Xiaodong Tian, Yuqiang Ma, Kai Yang, Bing Yuan
Highly ordered self-assembly of nanoparticles (NPs) in a large scale promises attractive potential in optical modulation of the NPs for illuminating, imaging and sensing applications. In this work, a type of multi-lamellar nanocomposite membranes composed of phospholipid multilayers and Si NPs sandwiched between each adjacent lipid layers was fabricated via a facile co-assembly method. X-ray reflectivity (XRR), grazing incident X-ray diffraction (GIXRD) and TEM measurements verified the highly ordered arrangement of NPs within the multilayers with a controlled in-plane inter-particle separation from ∼7 nm to ∼14 nm...
July 2, 2018: Colloids and Surfaces. B, Biointerfaces
Zhenhua Chen, Xinyan Lv, Mengen Zhao, Peng Zhang, Xiuli Ren, Xifan Mei
The treatment of bone infection requires drug carriers take large number of cargo, be antibacterial, promote proliferation and differentiation of osteoblasts. Herein, we proposed a strategy of preparing pH responsive, antibacterial, multistage structured microspheres encapsulated with green tea polyphenol used for minimally invasive treatment of bone infection. Tea polyphenol (TP) were encapsulated by porous silica nanospheres (SiO2 NSs). Then, sodium alginate (SA) microgel spheres (MSs) were prepared to encapsulate a lot of TP loaded SiO2 NSs...
July 2, 2018: Colloids and Surfaces. B, Biointerfaces
Ashish Baldi, Monika Chaudhary, Sheshank Sethi, Abhiav, Ramesh Chandra, Jitender Madan
Poor drug solubility and bioavailability remain a significant and frequently encountered concern for pharmaceutical scientists. Nanoscaled lipid drug delivery systems (NSLDDS) have exhibited great potentials in oral delivery of poorly water-soluble drugs, primarily for lipophilic drugs, with several successful clinical products. In the past few years, we have find out that optimized composition of drug in lipid, surfactant, or mixture of lipid and surfactant omits the solubility, permeability and bioavailability issues, which are potential limitations for oral absorption of poorly water-soluble drugs...
July 2, 2018: Colloids and Surfaces. B, Biointerfaces
Chad Curtis, Dorsa Toghani, Ben Wong, Elizabeth Nance
Drug delivery to the brain is challenging due to a highly regulated blood-brain barrier (BBB) and a complex brain microenvironment. Nanoparticles, due to their tailorability, provide promising platforms to enhance therapeutic delivery and achieve controlled release and disease-specific localization in the brain. However, we have yet to fully understand the complex interactions between nanoparticles and the biological environments in which they operate. It is important to perform a systematic study to characterize nanoparticle behavior as a function of ion composition, concentration, and pH in cerebrospinal fluid (CSF)...
June 30, 2018: Colloids and Surfaces. B, Biointerfaces
Abhignyan Nagesetti, Anthony J McGoron
No abstract text is available yet for this article.
June 30, 2018: Colloids and Surfaces. B, Biointerfaces
Diana Costa, Artur J M Valente, João A Queiroz, Ângela Sousa
Researchers still hold for the development of a safety and advanced delivery system able of efficient therapeutic action. The co-delivery of different payloads is part of this strategy and has already demonstrated to be a valuable tool against the most severe diseases. In the pursuit of an "ideal" drug/gene co-delivery vector for cancer therapy, we present a complete comparison study of different morphology and molecular weight polyethylenimine (PEI)/p53 encoding plasmid DNA (pDNA) polyplexes. Besides pDNA, also methotrexate (MTX) has been loaded into PEI/pDNA nanoparticles...
June 30, 2018: Colloids and Surfaces. B, Biointerfaces
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"