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Colloids and Surfaces. B, Biointerfaces

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https://www.readbyqxmd.com/read/30219579/dynamic-agent-of-an-injectable-and-self-healing-drug-loaded-hydrogel-for-embolization-therapy
#1
Xiaqing Zhou, Yongsan Li, Shuang Chen, Ya-Nan Fu, Shihui Wang, Guofeng Li, Lei Tao, Yen Wei, Xing Wang, Jun F Liang
Embolic agents are crucial for trans-catheter arterial embolization (TAE) in the treatment of various unresectable malignant tumors. Although solid particles, liquid oils, and some polymeric hydrogels have proved their capacities for embolic therapies, the low efficiency, time sensitivity, and cytotoxicity are still considered as challenges. In this study, we developed a three-component dynamic self-healing hydrogel to overcome these limitations. With the help of the Schiff-base bonding, both glycol-chitosan and carbazochrome, containing amine groups, react with dibenzaldehyde-terminated poly(ethylene-glycol) (DF-PEG), forming the dynamic self-healing hydrogels under a mild condition within 200 s...
September 10, 2018: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/30218982/manganese-dioxide-nanorods-electrochemically-reduced-graphene-oxide-nanocomposites-modified-electrodes-for-cost-effective-and-ultrasensitive-detection-of-amaranth
#2
Quanguo He, Jun Liu, Xiaopeng Liu, Guangli Li, Peihong Deng, Jing Liang
A novel manganese dioxide nanorods-electrochemically graphene oxide nanocomposites modified glassy carbon electrode (MnO2 NRs-ErGO/GCE) was developed for the rapid and sensitive detection of Amaranth in foodstuffs. The morphology, structure and composition of MnO2 NRs, ErGO, and MnO2 /ErGO were characterized by SEM and XRD. The electrochemical behavior of Amaranth on the bare GCE, ErGO/GCE, and MnO2 NRs-ErGO/GCE were investigated by cyclic voltammetry and electrochemical impedance spectroscopy. The voltammetric conditions (including pH, scan rate, accumulation potential as well as time) were optimized systematically...
September 9, 2018: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/30218981/drug-in-mucoadhesive-type-film-for-ocular-anti-inflammatory-potential-of-amlodipine-effect-of-sulphobutyl-ether-beta-cyclodextrin-on-permeation-and-molecular-docking-characterization
#3
Ashirbad Nanda, Rudra Narayan Sahoo, Arunima Pramanik, Rajaram Mohapatra, Sukanta Kumar Pradhan, Arun Thirumurugan, Debajyoti Das, Subrata Mallick
Mucoadhesive type ocular film has been prepared for studying the anti-inflammatory potential of amlodipine (AML) on carrageenan-induced rabbit model and the effect of sulphobutyl-ether-beta-cyclodextrin on corneal permeation was tested. Hydroxypropyl methylcellulose (HPMC) ocular film was prepared after complexation of amlodipine with β-cyclodextrin, (BCD), hydroxypropyl β-cyclodextrin (HPCD), and sulfobutylether β-cyclodextrin (SBCD). The film without cyclodextrin showed a maximum swelling, and erosion to the highest extent...
September 8, 2018: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/30218985/a-novel-electrochemical-sensor-based-on-electrode-modified-with-gold-nanoparticles-and-molecularly-imprinted-polymer-for-rapid-determination-of-trazosin
#4
Mahmoud Roushani, Zeynab Jalilian, Azizollah Nezhadali
A novel molecularly imprinted polymer sensor for fast and direct determination of trazosine (TR) was studied. The voltammetric sensor based on molecularly imprinted polymer (MIP) with disposable gold nanoparticles modified screen printed carbon electrode (MIP/AuNPs/SPCE) is developed for the determination of TR. Under the optimum conditions, the peak current of the sensor and TR concentration showed a good linear relationship over the range from 2.0 to 250.0 μM, with a low detection limit (S/N = 3) of 0...
September 7, 2018: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/30218984/surface-and-swelling-properties-of-mucoadhesive-blends-and-their-ability-to-release-fluconazole-in-a-mucin-environment
#5
A Bartkowiak, M Rojewska, K Hyla, J Zembrzuska, K Prochaska
The aim of this study is to characterize the matrices for the controlled release of fluconazole and to expand the knowledge of their physicochemical properties that influence the process of mucoadhesion. Polymeric carriers of fluconazole were prepared using the following mucoadhesive polymers: Carbopol 974 P NF, Noveon AA-1, HPMC, HEC, chitosan and film-forming polymer Kollidon VA 64. The potential mucoadhesive properties of the polymers and their blends were evaluated by measuring the wettability and then calculating the surface free energy defined by OWRK and vOCG models, determining the polar and dispersion forces, spreading coefficients and work of adhesion of polymers and their blends with fluconazole in the form of tablets...
September 6, 2018: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/30216905/polyaconitic-acid-functional-amine-azo-dye-composite-as-a-novel-hyper-branched-polymer-for-cotton-fabric-functionalization
#6
Asmaa Aboelnaga, Sahar Shaarawy, Ahmed G Hassabo
A new hyperbranched polymer based on aconitic acid and two different amine (triethnaol amine and diethylenetriamine) with different functional groups; hydroxyl and amine groups respectively was successfully synthesised by A2B3 polymerization technique and characterised using Fourier Transform Infrared (FT-IR), Nuclear Magnetic Resonance (NMR), rheological properties, antimicrobial and cytotoxicity activity. In addition, a new heterocyclic azo dye was synthesised and characterised using FT-IR, NMR, mass spectra and antimicrobial activity...
September 6, 2018: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/30218983/skin-permeable-liposome-improved-stability-and-permeability-of-bfgf-against-skin-of-mice-with-deep-second-degree-scald-to-promote-hair-follicle-neogenesis-through-inhibition-of-scar-formation
#7
He-Lin Xu, Pian-Pian Chen, Li-Fen Wang, Meng-Qi Tong, Zi-Hui Ou, Ying-Zheng Zhao, Jian Xiao, Ting-Ling Fu, Wei-Xue
Excessive deposition of extracellular matrix (ECM) usually resulted in scar formation during wound healing, which caused skin dysfunction, such as hair loss. Basic fibroblast growth factor (bFGF) was very helpful for promoting hair follicle neogenesis and regulating the remodeling of ECM during wound healing. Because of its poor stability in wound fluids and low permeability against the dense wound scar, the repairing quality of bFGF on wound was hindered largely in clinical practice. To overcome these drawbacks, herein, a novel liposome with silk fibroin hydrogel core (bFGF-SF-LIP) was firstly prepared to stabilize bFGF, followed by insertion of laurocapam, a permeation enhancer, into the liposomal membrane to construct a skin-permeable liposome (SP-bFGF-SF-LIP)...
September 5, 2018: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/30216904/surface-charging-by-the-cold-plasma-discharge-of-lentil-and-pepper-seeds-in-comparison-with-polymers
#8
Yekaterina Shapira, Gilad Chaniel, Edward Bormashenko
Cold plasma treatment charges organic surfaces. Surface density of the electrical charge supplied by cold radiofrequency plasma to the pepper and lentil seeds and various polymers: polyethylene, polystyrene, polycarbonate and poly(methyl methacrylate) was established experimentally. The surface charge density for all of studied interfaces, with one exception of polycarbonate was estimated as σ≈0.75-3.7μC/m2 ; for the polycarbonate it was almost an order of magnitude larger, namely σ≈7-9μC/m2 . The kinetics of the surface charge leakage was studied...
September 5, 2018: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/30216903/antimicrobial-dispersions-and-films-from-positively-charged-styrene-and-acrylic-copolymers
#9
Kamil Wojciechowski, Marcin Kaczorowski, Jolanta Mierzejewska, Paweł Parzuchowski
Antimicrobial properties of methyl methacrylate - ethyl acrylate and styrene - ethyl acrylate copolymers, both as latexes and after film formation were tested. The polymers were synthesized using a cationic surfactant, cetytrimethylammonium bromide (CTAB) as an emulsifier, in presence of either a cationic or an anionic initiator. The resulting latex particles showed sizes between 50 and 320 nm (larger for the anionic initiator), and ζ-potential between +30 and +70 mV (more positive for the cationic initiator)...
September 5, 2018: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/30212690/burkholderia-cepacia-immobilized-on-eucalyptus-leaves-used-to-simultaneously-remove-malachite-green-mg-and-cr-vi
#10
Li Gan, Fengfei Zhou, Gary Owens, Zuliang Chen
A multifunctional biomaterial capable of simultaneously removing malachite green (MG) and Cr(VI) was prepared by immobilizing Burkholderia cepacia (B. cepacia) on eucalyptus leaves (EL). The maximum uptake of MG (60 mg/L) and Cr(VI) (20 mg/L) were 94.8% and 71.9% respectively, which was more efficient than when using EL or free cells alone. SEM-EDS demonstrated that B. cepacia was attached to EL and that Cr(VI) was biosorbed into the immobilized cells. FTIR showed that the degradation by functional groups of immobilized cells was in keeping with the products, detected by GC-MS, which suggested that MG could be degraded to 4-dimethylamino benzophenone and 4-dimethylamino phenol...
September 5, 2018: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/30212689/physicochemical-characterization-of-solid-lipid-nanoparticles-comprised-of-glycerol-monostearate-and-bile-salts
#11
Paurnima Talele, Saugata Sahu, Ashok Kumar Mishra
Successful applications of solid lipid nanoparticles (SLNs) rely on their physicochemical properties which are mainly governed by their comprising materials (e.g., lipids, emulsifiers) and preparation methods. We have prepared biocompatible solid lipid nanoparticles with glycerol monostearate as lipid and varying combinations of bile salts sodium deoxycholate and sodium cholate (bile salts to lipid ratio 8% w/w) as emulsifiers. The detailed characterization of solid lipid nanoparticles was performed using a combination of light scattering, microscopic, calorimetric, and spectroscopic techniques...
September 5, 2018: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/30205340/preparation-and-study-of-the-antibacterial-ability-of-graphene-oxide-catechol-hybrid-polylactic-acid-nanofiber-mats
#12
Qingmiao Zhang, Qin Tu, Michael E Hickey, Jingcheng Xiao, Bo Gao, Chang Tian, Peng Heng, Ying Jiao, Tangqiong Peng, Jinyi Wang
The functionalization of electrospun mats with antimicrobial nanomaterials is an attractive strategy when developing functional graphene oxide coating materials to prevent bacterial colonization on surfaces. In this study, we demonstrated a simple approach to produce antimicrobial electrospun mats by dip-coating a polylactic acid (PLA) nanofiber into a graphene oxide-catechol derivative. PLA was first electrospun to yield narrow-diameter polymeric nanofibers. We then modified the graphene oxide (GO) with a catechol derivative - dopamine methacrylamide monomer (DMA) - to synthesize a GO-DMA nanocomposite material which exhibited robust antimicrobial properties...
September 5, 2018: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/30205339/marine-microorganisms-for-synthesis-of-metallic-nanoparticles-and-their-biomedical-applications
#13
REVIEW
Maheshkumar Prakash Patil, Gun-Do Kim
Nanotechnology has become one of the most in demand technologies applied in different fields of science. Metallic nanoparticles synthesis using marine microorganisms has been received global attention due to their extensive applications in biomedical science. The use of marine microbes for metallic nanoparticles synthesis is eco-friendly, time saving, and inexpensive. An eco-friendly method is essential to minimize waste and protect environment. Recently, marine microorganisms are recognized an eco-friendly and efficient way to utilize as potential biofactories for synthesis of metallic nanoparticles...
September 5, 2018: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/30199763/lotus-leaf-inspired-design-of-calcium-alginate-particles-with-superhigh-drug-encapsulation-efficiency-and-ph-responsive-release
#14
Botao Song
Drug delivery systems with high drug encapsulation efficiency and controlled release are of great importance in biomedical fields. Herein, we report an ingenious approach inspired from the lotus leaf possessing the ability of strong repellency to water, which enables the rapid fabrication of drug-loaded calcium alginate (Ca-Alg) particles with high drug encapsulation efficiency and controlled drug delivery. The design is achieved by introducing aqueous droplets containing the mixture of dilute sodium alginate solution, dilute calcium chloride solution, and drug onto the superhydrophobic substrate...
September 3, 2018: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/30199765/influence-of-modified-silica-nanoparticles-on-phase-behavior-and-structure-properties-of-dppc-monolayers
#15
Xiaoqi Ye, Changchun Hao, Juanjuan Yang, Runguang Sun
In this work, the effect of silica nanoparticles (NPs) adding to DPPC monolayer and the interaction between DPPC and silica nanoparticles are studied. Silica nanoparticles are prepared by microemulsion, meanwhile, DMDCS and APTES are used to modify silica NPs to get three types of modified silica NPs. These samples are mixed with DPPC to form mixed monolayer. By using the atomic force microscope (AFM), surface pressure-area and pressure-time isotherms, the effects of different hydrophilic-hydrophobic silica nanoparticles on the interface of lipid monolayer is analyzed...
September 1, 2018: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/30199764/cellulose-acetate-essential-oil-nanocapsules-with-antimicrobial-activity-for-biomedical-applications
#16
Ioannis L Liakos, Florin Iordache, Riccardo Carzino, Alice Scarpellini, Michele Oneto, Paolo Bianchini, Alexandru Mihai Grumezescu, Alina Maria Holban
This study aimed to obtain bioactive nanosystems by combining cellulose acetate with three selected essential oils (EOs) to create spherical nanocapsules (NCs) using the solvent/anti-solvent technique. The biological activity of the obtained NCs was promoted by the use of some antimicrobial EOs: Peppermint, Cinnamon and lemongrass which were grafted on the cellulose acetate molecules. Due to their chemistry, such as long hydrocarbon tails and heads with functional groups these EOs were playing also the role of surfactant-like substance facilitating the formation of NCs...
August 31, 2018: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/30196231/deformation-of-giant-unilamellar-vesicles-under-osmotic-stress
#17
Wei Zong, Qingchuan Li, Xunan Zhang, Xiaojun Han
Biological membrane plays an important role in maintaining an osmotic equilibrium between the cytoplasm and the extracellular solution of cells. Here, the giant unilamellar vesicles (GUVs) as cell models were used to investigate the effect of osmotic stress on phospholipid membranes. The deformation of GUVs, including inward budding and outward budding, was systematically investigated by the osmotic press from glucose, sucrose, LiCl, and KCl solutions. The permeability (P) of DMPC, DMPC/10 mol% Chol GUVs, DMPC/25 mol% Chol GUVs, and DMPC/40 mol% Chol GUVs in glucose, sucrose, LiCl, and KCl solutions were all obtained...
August 31, 2018: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/30196230/understanding-the-antimicrobial-activity-of-water-soluble-%C3%AE-cyclodextrin-alamethicin-complex
#18
Mengke Zhang, Jinpeng Wang, Yuan Lyu, Maya Fitriyanti, Hu Hou, Zhengyu Jin, Xiao Zhu, Ganesan Narsimhan
In our previous investigation (Zhang et. al., J. Functional Foods 40 (2018) 700-706), we have proposed a method of complexation of alamethicin (ALM) with γ-cyclodextrin (γ-CD) to increase the solubility and demonstrated an enhancement in its antimicrobial activity against Listeria monocytogenes. In this study, transmission electron microscopy of L. monocytogenes treated with γ-CD/ALM complex indicated cell lysis due to pore formation. This was further corroborated by fluorescent dye leakage from DMPC/cholesterol liposomes when exposed to γ-CD/ALM complex for molar ratios of 1, 5 and 10...
August 31, 2018: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/30196227/phase-segregated-membrane-model-assessed-by-a-combined-spr-afm-approach
#19
M Antonieta Daza Millone, Romina F Vázquez, Sabina M Maté, María E Vela
Model biomembranes can provide valuable insights into the properties of complex biological membranes. Among several techniques, Surface Plasmon Resonance (SPR) provides a label-free analysis of the interactions of bioactive molecules with biomembranes with an experimental setup that allows mimicking biological environments. Nevertheless, protocols that enable the preparation of stable supported membrane systems with reproducible structural and functional properties on the biosensor chip are still needed. In this work, we present a simple protocol to modify SPR substrates that allows the formation of a phase-segregated supported lipid bilayer (SLB)...
August 31, 2018: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/30195159/disulfide-based-pegylated-prodrugs-reconversion-kinetics-self-assembly-and-antitumor-efficacy
#20
Zichen Xie, Jianfeng Song, Heng Zhang, Yifei Zhuang, Shenqi Xie, Yongliang Li, Zhimin Li, Mei Liu, Keyu Sun
The prodrug strategy serves well in drug formulation and delivery. Two disulfide-based PEGylated prodrugs were developed and the drug reconversion upon different conditions were studied in detail. The reconversion-induced oversaturation phenomenon was firstly reported here. We found the prodrug can co-assemble with parent drug via π-π stacking into well-defined nanoparticles. The PEG layer of the self-assembled nanoparticles improved the stability of the PEGylated prodrug by reducing the contact with biological enzymes...
August 31, 2018: Colloids and Surfaces. B, Biointerfaces
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