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International Journal of Surgical Pathology

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https://www.readbyqxmd.com/read/28817996/meningioma-with-tyrosine-rich-crystalloids-a-case-report-and-review-of-the-literature
#1
Erik Reinertsen, Stewart G Neill, Kambiz Nael, Daniel J Brat, Costas G Hadjipanayis
We report a case of fibrous meningioma with tyrosine-rich crystalloid in the frontal lobe of a middle-aged woman. The patient presented with a history of several years of worsening headaches and blurry vision, which progressed to include syncopal episodes and right-sided weakness. Imaging demonstrated a dural-based extra-axial mass arising from the right orbital roof and extending superiorly along the right frontal convexity causing right-to-left midline shift. The patient underwent a craniotomy and operative resection...
August 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28805130/melan-a-antibody-cross-reactivity-in-molluscum-contagiosum-bodies
#2
David Creytens
No abstract text is available yet for this article.
August 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28805108/a-clinicopathological-study-of-small-lung-adenocarcinoma-1-cm-or-less-in-size-emphasis-on-histological-subtypes-associated-with-lymph-node-metastasis-and-recurrence
#3
Wei Zhao, Hui Wang, Jun Xie, Bo Tian
BACKGROUND: The aim of this study was to assess the prognostic significance of the newly proposed 2015 World Health Organization (WHO) lung adenocarcinoma classification for patients undergoing resection for small (≤1 cm) lung adenocarcinoma. We also investigated whether lobectomy offers prognostic advantage over limited resection for this category of tumors. METHODS: A retrospective study of resected pulmonary adenocarcinomas (n = 83) in sizes 1 cm or less was carried out in which comprehensive histologic subtyping was assessed according to the 2015 WHO classification on all consecutive patients who underwent lobectomy or limited resection between 1998 and 2012...
August 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28793830/warthin-tumor-like-mucoepidermoid-carcinoma
#4
Nicholas Heatley, Kevin J Harrington, Khin Thway
Mucoepidermoid carcinoma (MEC) shows a wide morphologic spectrum, including epithelium with oncocytic or squamous metaplastic changes overlying a prominent cystic architecture, as well as tumor-associated lymphoid tissue. We illustrate a case of MEC of the parotid in a 17-year-old female, in which all these features occurred extensively, such that they accounted for almost the entire neoplasm, and closely mimicked Warthin tumor histologically. This highlights the need for diagnostic awareness of this particular morphologic variant of MEC, as patients could potentially be inappropriately discharged from follow-up if diagnosed with a benign neoplasm...
August 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28793826/toxoplasma-appendicitis-a-once-in-a-lifetime-diagnosis
#5
Anisha M Fernandes, Maheshkumar M Lakhe, Sanjay A Pai
Toxoplasmosis is generally asymptomatic in immunocompetent individuals, but it can be life-threatening in immunocompromised patients. We present a case of a 62-year-old man with clinical features of acute appendicitis. Histology showed a transmural infiltrate of eosinophils. In addition, there were reactive lymphoid follicles with histiocytes in the submucosa and tachyzoites in the muscularis propria. Immunohistochemistry confirmed the diagnosis of toxoplasma appendicitis. Serological evaluation yielded negative results...
August 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28784007/tactile-corpuscle-like-bodies-wagner-meissner-corpuscles-of-the-colorectum-a-series-of-5-cases
#6
Aaron R Huber, Diana Agostini-Vulaj, Michael G Drage, Julie W Lemmon
An increase in screening colonoscopies has led to the recent identification and description of several benign mesenchymal proliferations within the colon that may be sampled incidentally or as mucosal polyps. Tactile corpuscle-like bodies (TCLBs) (also known as Wagner-Meissner corpuscles) are Schwannian-derived specialized mechanosensors found in glabrous skin and some mucosal sites. TCLBs are not a normal component of gastrointestinal mucosa but they have been reported in the esophagus, stomach, gastroesophageal junction, and colorectum...
August 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28783989/coexistent-squamous-cell-carcinoma-and-granular-cell-tumor-of-head-and-neck-region-report-of-two-very-rare-cases-and-review-of-the-literature
#7
Danila Caroppo, Grazia Salerno, Francesco Merolla, Massimo Mesolella, Gennaro Ilardi, Francesca Pagliuca, Gianfranco De Dominicis, Luigi Califano, Giuseppe Ciancia, Daniela Russo, Massimo Mascolo
Granular cell tumor (GCT), a relatively rare neuroectodermal tumor occurring most often in the head and neck region, is not uncommonly associated with pseudoepitheliomatous hyperplasia of the overlying surface epithelium, which may be at times nonreadily distinguishable from well-differentiated squamous cell carcinoma (SCC). To the best of our knowledge, only a handful of coexisting SCC and GCT, mostly described in the esophagus, have been reported in (the current) literature so far. We herein report 2 new cases of coexisting GCT and SCC of the head and neck region, located, respectively, in larynx and tongue; comment on their clinical, imaging, and pathologic features; and discuss their management...
August 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28764610/synovial-sarcoma-mimicking-pleomorphic-hyalinizing-angiectatic-tumor-of-soft-parts-a-case-report
#8
Neha Gupta, Samuel Kenan, Leonard B Kahn
Synovial sarcoma is a high-grade sarcoma commonly affecting young adults. The sites of involvement include soft tissue near joints, lung, pleura, mediastinum, larynx, kidney, and buttocks. Histologic types include monophasic, biphasic, and undifferentiated. We report a unique case of synovial sarcoma with low-grade histologic features mimicking pleomorphic hyalinizing angiectatic tumor (PHAT) with indolent behavior for a period of 10 years. The tumor showed angiectatic blood vessels with fibrinous cuffing, hypocellular and hypercellular spindle cell areas with rare mitoses, and focal atypia in a myxoid background...
August 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28738748/liesegang-rings-extremely-rare-structures-in-malignant-lesions
#9
Sankalp Sancheti, Shivani Jain
No abstract text is available yet for this article.
July 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28718332/a-peculiar-form-of-breast-fat-necrosis-simulating-hyaline-ring-granuloma-so-called-pulse-granuloma-a-rare-complication-of-hyperparathyroidism
#10
Maria García-Martos, Angel Panizo-Santos
Pulse granuloma is a rare, foreign body inflammatory reaction that occurs mainly in the oral cavity. It is exceedingly rare elsewhere, with only isolated cases described in the literature. We report the case of a 79-year-old woman with a history of normocalcemic hyperparathyroidism who presented to our hospital with a painful 4-cm lump in the upper quadrants-upper outer quadrant of her left breast. The clinical and radiological (BIRADS-5) findings were indicative of a malignant lesion. However, core needle biopsy revealed features simulating hyaline ring granuloma (pulse granuloma-like)...
July 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28705040/minimal-limited-pseudohyperplastic-prostatic-adenocarcinoma-in-needle-prostatic-biopsy
#11
Julian Arista-Nasr, Braulio Martinez-Benitez, Alejandra Mijangos-Trejo, Leticia Bornstein-Quevedo, Jorge Albores-Saavedra
BACKGROUND: Study of minimum adenocarcinoma has been done almost exclusively on conventional acinar adenocarcinoma. Pseudohyperplastic adenocarcinoma can be confused with benign lesions because of its well-differentiated appearance and has not been studied when the biopsy shows few malignant glands (limited carcinoma). METHODS: We reviewed 94 pseudohyperplastic adenocarcinomas diagnosed in prostatic biopsies for a period of 12 years and selected those measuring less than 1 mm or involving less than 5% of the biopsied tissue...
July 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28697692/primary-intra-aortic-epstein-barr-virus-positive-large-b-cell-lymphoma-presenting-as-aortic-mural-thrombosis-an-entity-distinct-from-intravascular-large-b-cell-lymphoma
#12
Ryuta Nakao, Aki Sakashita, Atsushi Omoto, Osamu Sato, Yoko Hino, Akio Yanagisawa, Yoji Urata
Intravascular selective growth of neoplastic B lymphocytes is a characteristic finding of intravascular large B-cell lymphoma (IVLBCL). However, because neoplastic B cells of IVLBCL grow merely in the lumina of capillaries or small vessels, primary IVLBCL of the great vessels is considered exceptional. To our knowledge, only 2 primary B-cell lymphomas in the lumina of the vena cava have been reported. However, there has been no report of primary B-cell lymphoma with intra-aortic growth. We describe a novel manifestation of primary Epstein-Barr virus-positive large B-cell lymphoma mainly affecting the lumina of the aorta and its major branches in a 76-year-old man...
July 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28697683/metastatic-sclerosing-epithelioid-fibrosarcoma-in-bone-marrow
#13
Rana Asakra, Shane Zaidi, Khin Thway
Sclerosing epithelioid fibrosarcoma (SEF) is an aggressive neoplasm thought to be related to low-grade fibromyxoid sarcoma, which typically occurs in middle-aged adults in the deep soft tissues of the lower extremities and trunk. It comprises nests and cords of relatively uniform epithelioid polygonal cells with clear or eosinophilic cytoplasm in densely sclerotic stroma, and it is typically associated with EWSR1 gene rearrangements, and most commonly EWSR1-CREB3L1 fusions. As primary SEF can arise in bone, and bone is also a common metastatic site for SEF, its recognition at this site is important...
July 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28697675/malignant-mixed-epithelial-and-stromal-tumor-of-the-kidney-with-2-simultaneous-renal-carcinomas-in-a-male-patient-case-report-and-review-of-the-literature
#14
Aileen Grace P Arriola, Benjamin L Taylor, Sophia Ma, S Bruce Malkowicz, Priti Lal
The majority of mixed epithelial and stromal tumors (MEST) of the kidney are benign entities found in female patients. Malignant MEST of the kidney is an extremely rare entity that often behaves clinically similar to an undifferentiated sarcoma. We report a case of a malignant MEST with synchronous papillary and clear cell renal cell carcinomas (RCCs) in a 61-year-old Caucasian man who presented with an incidental finding of a left renal mass on workup for back pain. The patient underwent a left radical nephrectomy, with histopathology confirming a malignant MEST, intimately associated papillary RCC, and separate adjacent focus of clear cell RCC...
July 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28697655/functional-ulnar-nerve-paraganglioma-first-documented-occurrence-in-the-extremity-with-hitherto-undescribed-associated-extensive-glomus-cell-hyperplasia-and-tumorlet-formation
#15
Louis Tsun Cheung Chow, Michael Ho Ming Chan, Simon Kwok Chuen Wong
Extra-adrenal paraganglioma has never been described in the extremities. A 34-year-old woman complained of an enlarging mass in the right forearm for 18 months. Imaging showed a circumscribed vascular tumor attached to the ulnar nerve; biopsy revealed features of paraganglioma. The resected tumor consisted of zellballen pattern of chief cells staining positively for chromogranin with surrounding S100-positive sustentacular cells. The chief cells contained many neurosecretory granules and mitochondria, whereas the sustentacular cells contained a large amount of rough endoplasmic reticulum and some microfilaments...
July 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28691603/dichorionic-twins-discordant-for-massive-perivillous-fibrinoid-deposition-report-of-a-case-and-review-of-the-literature
#16
Ona Faye-Petersen, Adrienne Sauder, Ydamis Estrella, Debra S Heller
Massive perivillous fibrinoid deposition (MFD) and maternal floor infarction (MFI) are lesions of unknown etiology associated with poor perinatal outcomes, including fetal intrauterine growth restriction and neurodevelopmental injury, high risks of pregnancy loss, and recurrence in subsequent gestations. MFI comprises massive intervillous fibrinoid deposition concentrated at the maternal floor. MFD is a similar lesion but is diffuse within the parenchyma. MFD/MFI lesions represent a spectrum of severity of cloak-like perivillous fibrinoid deposition, and there is mounting evidence that, often, they represent sequelae of immune-mediated phenomena and/or an imbalance in factors that normally maintain the fluidity of blood in the maternal space...
July 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28675980/a-combined-deposition-of-lanthanum-and-%C3%AE-2-microglobulin-related-amyloid-in-the-gastroduodenal-mucosa-of-hemodialysis-dependent-patients-an-immunohistochemical-electron-microscopic-and-energy-dispersive-x-ray-spectrometric-analysis
#17
Takayoshi Komatsu-Fujii, Hideyuki Onuma, Youichi Miyaoka, Noriyoshi Ishikawa, Asuka Araki, Nahoko Ishikawa, Tomohiko Yamamoto, Tomoko Mishiro, Kyoichi Adachi, Yoshikazu Kinoshita, Pamela Tauchi-Nishi, Riruke Maruyama
Lanthanum carbonate (LC) is a new type of phosphate adsorbent used to treat patients with hyperphosphatemia caused by chronic kidney diseases. Recent studies have pointed out that lanthanum deposition can be found in the cytoplasm of histiocytes in the gastroduodenal mucosa of these patients. On the other hand, it is well known that patients on long-term hemodialysis can develop deposition of β2-microglobulin-related amyloid (Aβ2M) mainly around joints. However, involvement of the gastrointestinal tract by hemodialysis-associated amyloidosis has been thought to be rare, and therefore only Aβ2M, if any, has been reported to accumulate in the vascular walls of the submucosa and muscularis propria...
July 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28675973/diffuse-melanosis-in-pericolic-lymph-nodes-associated-with-laxative-abuse-and-colorectal-cancer
#18
Anna Renda, Contardo Vergani, Marco Venturi, Stefano Ferrero, Alessandro Del Gobbo
No abstract text is available yet for this article.
July 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28675958/congenital-myoepithelial-carcinoma-of-soft-tissue-associated-with-cystic-myoepithelioma
#19
Chiara Baldovini, Stefania Sorrentino, Cesar Augusto Alves, Gianluca Piatelli, Alberto Garaventa, Giovanni Morana, Paolo Nozza
Myoepithelial neoplasms of soft tissue represent a heterogeneous group of lesions, encompassing both benign entities as myoepithelioma (ME) and highly aggressive tumors as myoepithelial carcinoma (MEC). We describe a case of pediatric soft tissue MEC with peculiar features that may lead to misdiagnosis: congenital onset and presence of a benign component with predominant cystic structure. Few cases of congenital MEC have been reported, but the coexistence of MEC with ME is even more rare, accounting for less than 1% of myoepithelial tumors...
July 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28675947/pulmonary-blastoma-in-children-report-of-a-rare-case-and-review-of-the-literature
#20
Chia-Chi Chen, Sheau-Fang Yang, Pei-Chin Lin, Chi-Wen Luo, Shih-Hua Chou, Zen-Kong Dai, Hsin-Ling Yin
Pulmonary blastoma is a rare malignant lung tumor with aggressive behavior and dismal prognosis. It is extremely rare in children aged <18 years, and little is known about its genetic alteration and pathogenesis. Although surgical resection and adjuvant chemotherapy or radiotherapy have been applied in several cases, no standard treatment guidelines with sufficient evidence have been established. In this article, we report a case of a large pulmonary blastoma in a 7-year-old girl whose initial presentation was progressive dyspnea and productive cough...
July 1, 2017: International Journal of Surgical Pathology
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