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Journal of Heart Valve Disease

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https://www.readbyqxmd.com/read/29092127/iatrogenic-lutembacher-syndrome-after-percutaneous-mitral-commissurotomy
#1
Theodoros D Karamitsos, Chrysovalantou Nikolaidou, Athanasios Koutsakis, Kyriakos Anastasiadis, Charalambos Karvounis, Stavros Hadjimiltiades
Atrial septal defects (ASDs) are common immediately after percutaneous mitral commissurotomy (PMC). They are usually small, hemodynamically insignificant, and tend to decrease or disappear within 6 to 12 months. Herein, a case is described of persistent ASD in a patient with mitral valve stenosis who had undergone successful PMC three years previously. The patient had signs and symptoms of right heart failure and severe tricuspid regurgitation (TR) with borderline right ventricular systolic function on echocardiography, in addition to the ASD...
May 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/29092126/prosthetic-aortic-valve-endocarditis-without-evidence-of-vegetation
#2
Tasleem Katchi, Howard A Cooper, Srikanth S Yandrapalli, Sahil Khera, John Fallon, David Spielvogel, Wilbert S Aronow, Julio A Panza
Despite significant technological advances, the diagnosis of infective endocarditis (IE) remains a major challenge, and the condition continues to be associated with significant morbidity and mortality. Valvular vegetations have long been the diagnostic and pathologic hallmarks of IE. However, IE can be diagnosed even in the absence of vegetations using the modified Duke criteria. Vegetation-negative endocarditis is rare, and to the present authors' knowledge no cases of septic emboli in the absence of valvular vegetations have been reported...
May 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/29092125/significant-drop-in-right-atrial-pressure-does-not-influence-fractional-flow-reserve-coronary-assessment
#3
Roberto Scarsini, Gabriele Pesarini, Fausto Castriota, Corrado Vassanelli, Flavio Ribichini
The effect of a highly elevated level of right atrial filling pressure on fractional flow reserve (FFR) measurement remains unclear. Transcatheter tricuspid valve intervention, a recently introduced option for inoperable or high-risk patients, represents a unique model of in-vivo physiology to investigate the eventual influence of central venous pressure on coronary FFR measurements. The case is reported of a patient with a degenerated tricuspid surgical bioprosthesis who underwent transcatheter tricuspid valve-in-valve replacement and concomitant coronary functional assessment with FFR...
May 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/29092124/post-coital-acute-rupture-of-a-fenestrated-aortic-valve
#4
Aurélien Roumy, Xavier Jeanrenaud, René Pretre, Matthias Kirsch
Fenestrated aortic valve is a frequent condition which is, for most of the time, asymptomatic and generally has no influence on aortic valve competence. However, aortic valve regurgitation could occur, especially in the case of fibrous strand rupture. In this situation, acute aortic regurgitation is poorly tolerated and requires urgent surgical correction. Herein is presented the case of a 70-year-old patient who was admitted as an emergency for acute heart failure after coital exertion. Echocardiography revealed severe acute aortic regurgitation due to leaflet prolapse...
May 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/29092123/bileaflet-foldoplasty-in-barlow%C3%A2-s-disease
#5
Zain Khalpey, Badi Rawashdeh, Toshinobu Kazui, Scott Lick
Mitral valve repair is a feasible and preferable option for the treatment of Barlow's disease. Complex valve repair techniques, in contrast, often lead to increased cross-clamp times and low cardiac output syndrome. A simple, fast, and reproducible foldoplasty technique to reduce anterior and posterior mitral leaflet heights may improve coaptation and reduce mitral regurgitation. Accordingly, herein are described minimally invasive, successful trans-septal and robotic approaches for a bileaflet foldoplasty technique in two patients with Barlow's disease...
May 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/29092122/treatment-of-prosthetic-valve-thrombosis-with-bolus-dose-tenecteplase-an-experience-from-a-developing-country
#6
Rajesh Kumar Jha, Sandeep Bansal, H S Issar, Mayuresh Chaudhary, Sonu Sharma
BACKGROUND: Prosthetic valve thrombosis (PVT) in metallic prosthetic cardiac valves is not an uncommon condition, and has high mortality and morbidity. Although surgery is the traditional choice for PVT therapy, thrombolysis with newer agents has achieved good success rates. Many studies described in the western literature have used tissue plasminogen activators, while studies from developing countries have been largely based on the use of streptokinase and urokinase. Data regarding the use of newer agents such as tenecteplase are scant...
May 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/29092121/obstructive-thrombosis-of-left-sided-mechanical-heart-valves-clinical-profile-and-thrombolytic-therapy
#7
Arumugam Chandrakasu, Avinash Jayachandran, Pradeep Gopinath Nayar, Chokkalingam Meyyappan, Ganesh Narayan, Ahamed Basha Abdul Bari, Prince Johnson Samuel
BACKGROUND: Thrombosis of a mechanical prosthetic heart valve is a potentially life-threatening complication associated with a high mortality. Although thrombolytic therapy has been considered highly beneficial in this situation, very few studies have been conducted to monitor the effectiveness of such thrombolytic therapy among Asian populations. Hence, the study aim was to evaluate the clinical profile, efficacy and safety of the thrombolytic agent streptokinase (SK) in patients with obstructive thrombosis of a left-sided mechanical heart valve...
May 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/29092120/immunologic-responses-in-biological-and-mechanical-valve-prostheses-inflammation-and-functionality-are-not-always-related
#8
Alejandra Rodriguez-Hernandez, Maria Elena Soto, Jesus Vargas-Barron, Ricardo Marquez, Rafael Bojalil-Parra, Israel Perez-Torres, Jose Luis Salas-Pacheco, Valentin Jimenez-Rojas, Jose Antonio Arias-Godinez, Veronica Guarner-Lans
BACKGROUND: The aim of this retrospective study was to evaluate the inflammatory response in patients with aortic and/or mitral prostheses, and to correlate the level of inflammatory markers with prosthesis functionality. METHODS: A total of 48 patients with biological or mechanical prostheses was included in the study, in which levels of tumor necrosis factor-alpha (TNFα), interleukin (IL)-1, -4, and -6, interferon-gamma (IFNγ), osteopontin (OPN), intercellular adhesion molecule (ICAM), vascular cell adhesion molecule (VCAM), endothelin-1 and C-reactive protein were analyzed...
May 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/29092119/mir-92a-a-novel-potential-biomarker-of-rapid-aortic-valve-calcification
#9
Joseph Nader, Valérie Metzinger-Le Meuth, Pierre Maitrias, Jean-Régis Humbert, Benjamin Brigant, Christophe Tribouilloy, Laurent Metzinger, Thierry Caus
BACKGROUND: The study aim was to compare the tissular expression of microRNAs (miRs) in bicuspid and tricuspid valves, and to evaluate their use as potential novel biomarkers of aortic valve calcification in bicuspid valves. METHODS: A prospective single-center observational study was conducted on stenotic bicuspid and tricuspid human aortic valves. According to their potential role in valve vascular and valvular calcification, a decision was taken to include miR- 92a, miR-141, and miR-223 in this analysis...
May 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/29092118/carcinoid-valve-disease-a-case-report-and-review
#10
Daniel Heikali, Nelson Chang, Ramin Tabibiazar
In patients with carcinoid syndrome, the development of carcinoid valve disease typically carries an unfavorable prognosis. We present the case of a patient with significant valvular dysfunction secondary to carcinoid valve disease. Valve replacement surgery was complicated by the development of prosthetic valve degeneration, ultimately requiring percutaneous valve implantation in a valve-in-valve fashion. The technical details of the case, as well as a review of carcinoid valve disease, including its pathophysiology, clinical manifestations, diagnostic features and management considerations, are presented...
May 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/29092117/a-staged-approach-of-proximal-left-anterior-descending-coronary-artery-percutaneous-intervention-followed-by-minimally-invasive-valve-surgery
#11
Andrés M Pineda, Christos G Mihos, Juan P Rodriguez-Escudero, Joseph Lamelas, Nirat Beohar, Orlando Santana
BACKGROUND: A subset of patients requiring coronary revascularization of the proximal left anterior descending coronary artery (LAD) and valve surgery may benefit from a staged approach, rather than combined median sternotomy coronary artery bypass graft (CABG) and valve surgery. METHODS: A retrospective evaluation was made of the outcomes of patients with significant proximal LAD and valvular heart disease undergoing a staged approach of percutaneous coronary intervention (PCI) followed by minimally invasive valve surgery (MIVS) at the authors' institution between February 2009 and April 2014...
May 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/29092116/unexpected-problems-of-antithrombotic-therapy-with-an-unusual-side-effect-of-vitamin-k-antagonists-after-mitral-valve-replacement
#12
Benjamin Marchandot, Nathan Messas, Laurence Jesel, Annie Trinh, Marion Kibler, Antje Reydel, Patrick Ohlmann, Olivier Morel
Except for bleeding complications, vitamin K antagonists (VKAs) are known to have few undesirable side effects. Herein is presented the case of a 45-year-old woman in whom liver damage was induced by fluindione and warfarin after mitral valve replacement. Hepatotoxicity is a rare complication of VKAs, both in the French National and Drug Safety registry and the medical literature. A diagnosis of VKA-induced drug damage was confirmed by the absence of other etiologies, the chronological sequence, recurrence after re-exposure to VKA, and rapid improvements after discontinuation of the drug...
May 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/29092115/cardiac-amyloidosis-associated-with-enlargement-and-functional-impairment-of-the-mitral-annulus-insights-from-the-three-dimensional-speckle-tracking-echocardiographic-magyar-path-study
#13
Attila Nemes, Dóra Földeák, Árpád Kormányos, Péter Domsik, Anita Kalapos, Zita Borbényi, Tamás Forster
BACKGROUND: Cardiac amyloidosis (CA) is a rare condition characterized by the extracellular deposition of amyloidogenic proteins in the heart. The aim of the present study was to compare the size and function of the mitral annulus (MA) between CA patients and age- and gender-matched controls, using three-dimensional speckle-tracking echocardiography (3-D STE). METHODS: The study included 17 patients (mean age 64.2 ± 9.8 years) with CA, whose results were compared to 26 age- and gender-matched healthy controls (mean age 59...
May 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/29092114/remodeling-mitral-annuloplasty-ring-concept-with-preserved-dynamics-of-annular-height
#14
Søren N Skov, Diana M Røpcke, Marcell J Tjørnild, Christine Ilkjær, Jonas Rasmussen, Hans Nygaard, J M Hasenkam, Morten O Jensen, Sten L Nielsen
BACKGROUND: The configuration of the native annulus changes from nearly flat in the diastolic phase to saddle-shaped in the systolic phase. The present study was conducted to test a novel remodeling annuloplasty ring with built-in septal-lateral fixation and commissural axial flexibility so as to maintain the change in annular saddle shape. The study aim was to evaluate the in-vivo biomechanical performance of the novel annuloplasty ring, compared with the native valve and a semi-rigid and rigid annuloplasty ring...
May 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/29092113/progression-of-tricuspid-regurgitation-after-mitral-valve-replacement-for-rheumatic-heart-disease
#15
Ho H Q Tri, Pham N Vinh
BACKGROUND: Progression of tricuspid regurgitation (TR) may occur after mitral valve replacement (MVR). The study aim was to define the independent predictors for new severe TR after MVR to treat rheumatic heart disease. METHODS: A total of 413 patients (177 men, 236 women; mean age 40.9 ± 9.2 years) with rheumatic heart disease undergoing MVR without concomitant tricuspid valve repair at the authors' institute between 1995 and 2005, who did not have preoperative severe TR, were followed for at least one year postoperatively...
May 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/29092112/early-activation-of-growth-pathways-in-mitral-leaflets-exposed-to-aortic-regurgitation-new-insights-from-an-animal-model
#16
Ons Marsit, Olivier Royer, Marie-Claude Drolet, Marie Arsenault, Jacques Couet, Stéphane Morin, Robert A Levine, Philippe Pibarot, Jonathan Beaudoin
BACKGROUND: Mitral leaflet enlargement in patients with chronic aortic regurgitation (AR) has been identified as an adaptive mechanism potentially able to prevent functional mitral regurgitation (FMR) in response to left ventricular (LV) dilatation. The timing of valve enlargement is not known, and the related mechanisms are largely unexplored. METHODS: AR was induced in 58 rats, and another 54 were used as sham controls. Animals were euthanized at different time points after AR creation (48 h, one week, and three months), and AR severity, FMR and LV dilatation were assessed using echocardiography...
May 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/29092111/prevalence-of-bicuspid-aortic-valve-in-chinese-patients-with-aortic-valve-disease-a-systematic-review
#17
Xu Wang, Wei Wang
BACKGROUND: The aim of this systematic review was to assess the incidence of bicuspid aortic valve (BAV) in Chinese patients with aortic valve disease. METHODS: Articles published between January 2000 and January 2015 were retrieved, and those reporting numbers of BAVs were selected. Data relating to congenital BAV and rheumatic lesions with functional BAV that were available for analysis were also collected. RESULTS: A total of 4,070 articles (3,538 in Chinese, 532 in English) was retrieved, among which 3,954 were excluded and 116 were selected...
May 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/29092110/tavi-for-failed-valve-sparing-operations-in-hospital-and-mid-term-outcome
#18
Francesco Notaristefano, Salvatore Notaristefano, Rocco Sclafani, Matteo R Reccia, Roberto Annunziata, Uberto Da Col, Giuseppe Ambrosio, Claudio Cavallini
BACKGROUND: Although transcatheter aortic valve implantation (TAVI) is a steadily expanding treatment for the pathology of the aortic valve, its role in the replacement of native aortic valves following valve-sparing surgery has not been investigated. METHODS: Among 150 patients who underwent TAVI at the authors' institution, three (2%) had a failed valve-sparing operation. The in-hospital outcome, mid-term mortality, and valvular function of the three patients were evaluated retrospectively...
May 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/29092109/epicardial-adipose-tissue-thickness-independently-predicts-severe-aortic-valve-stenosis
#19
Amir A Mahabadi, Heike A Kahlert, Iryna Dykun, Bastian Balcer, Philipp Kahlert, Tienush Rassaf
BACKGROUND: Epicardial fat tissue (EAT) is associated with coronary as well as aortic valve calcification. The study aim was to determine whether EAT thickness is different in patients with and without aortic valve stenosis (AVS). METHODS: A cohort of 200 consecutive patients with severe AVS and 200 matched patients without AVS were included retrospectively in the study. EAT thickness was quantified, using transthoracic echocardiography, as the space between the epicardial wall of the myocardium and the visceral layer of the pericardium...
May 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/29092108/sutureless-versus-transfemoral-transcatheter-aortic-valve-implant-a-propensity-score-matching-study
#20
Giuseppe Santarpino, Ferdinand Vogt, Steffen Pfeiffer, Angelo M Dell'Aquila, Jürgen Jessl, Federica Cuomo, Che von Wardenburg, Theodor Fischlein, Matthias Pauschinger, Johannes Schwab
BACKGROUND: Transcatheter aortic valve implantation (TAVI), especially via the transfemoral (TF) route, is increasingly performed in patients considered in the 'gray zone' between TAVI and surgery. However, the best treatment option in this patient population remains to be established. METHODS: Since 2010, a total of 923 patients underwent either TAVI (n = 538) or sutureless aortic valve replacement (AVR) (n = 385) at the authors' institutions. Among these patients, 79 treated with TF-TAVI were compared with 79 propensity score-matched patients who had undergone elective isolated AVR with the sutureless Perceval bioprosthesis...
May 2017: Journal of Heart Valve Disease
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