Qiao Yang, Yaya Feng, Yuanxin Zhang, Mingshu Wang, Renyong Jia, Dekang Zhu, Shun Chen, Mafeng Liu, Xinxin Zhao, Ying Wu, Shaqiu Zhang, Bin Tian, Xumin Ou, Sai Mao, Juan Huang, Qun Gao, Di Sun, Zhen Wu, Yu He, Ling Zhang, Yanling Yu, Anchun Cheng
During the replication process, the herpesvirus genome forms the head-to-tail linked concatemeric genome, which is then cleaved and packaged into the capsid. The cleavage and packing process is carried out by the terminase complex, which specifically recognizes and cleaves the concatemeric genome. This process is governed by a cis-acting sequence in the genome, named the a sequence. The a sequence and genome cleavage have been described in some herpesviruses, but it remains unclear in duck plague virus. In this study, we analysed the location, composition, and conservation of a sequence in the duck plague virus genome...
January 3, 2024: Veterinary Research