journal
MENU ▼
Read by QxMD icon Read
search

Veterinary Research

journal
https://www.readbyqxmd.com/read/28705175/serotype-specific-role-of-antigen-i-ii-in-the-initial-steps-of-the-pathogenesis-of-the-infection-caused-by-streptococcus-suis
#1
Sarah Chuzeville, Jean-Philippe Auger, Audrey Dumesnil, David Roy, Sonia Lacouture, Nahuel Fittipaldi, Daniel Grenier, Marcelo Gottschalk
Streptococcus suis is one of the most important post-weaning porcine bacterial pathogens worldwide. The serotypes 2 and 9 are often considered the most virulent and prevalent serotypes involved in swine infections, especially in Europe. However, knowledge of the bacterial factors involved in the first steps of the pathogenesis of the infection remains scarce. In several pathogenic streptococci, expression of multimodal adhesion proteins known as antigen I/II (AgI/II) have been linked with persistence in the upper respiratory tract and the oral cavity, as well as with bacterial dissemination...
July 14, 2017: Veterinary Research
https://www.readbyqxmd.com/read/28662714/recall-t-cell-responses-to-bluetongue-virus-produce-a-narrowing-of-the-t-cell-repertoire
#2
José-Manuel Rojas, Teresa Rodríguez-Calvo, Noemí Sevilla
In most viral infections, recall T cell responses are critical for protection. The magnitude of these secondary responses can also affect the CD8 and CD4 epitope repertoire diversity. Bluetongue virus (BTV) infection in sheep elicits a T cell response that contributes to viremia control and could be relevant for cross-protection between BTV serotypes. Here, we characterized CD4(+) and CD8(+) T cell responses during primary and recall responses. During primary immune responses, both CD4(+) and CD8(+) T cell populations expanded by 14 days post-infection (dpi)...
June 29, 2017: Veterinary Research
https://www.readbyqxmd.com/read/28645300/bacterial-ghosts-as-adjuvants-mechanisms-and-potential
#3
REVIEW
Irshad A Hajam, Pervaiz A Dar, Gayeon Won, John Hwa Lee
Bacterial ghosts (BG) are empty cell envelopes derived from Gram-negative bacteria. They contain many innate immunostimulatory agonists, and are potent activators of a broad range of cell types involved in innate and adaptive immunity. Several considerable studies have demonstrated the effectiveness of BG as adjuvants as well as their ability to induce proinflammatory cytokine production by a range of immune and non-immune cell types. These proinflammatory cytokines trigger a generalized recruitment of T and B lymphocytes to lymph nodes that maximize the chances of encounter with their cognate antigen, and subsequent elicitation of potent immune responses...
June 24, 2017: Veterinary Research
https://www.readbyqxmd.com/read/28623956/differential-protein-expression-in-chicken-macrophages-and-heterophils-in-vivo-following-infection-with-salmonella-enteritidis
#4
Zuzana Sekelova, Hana Stepanova, Ondrej Polansky, Karolina Varmuzova, Marcela Faldynova, Radek Fedr, Ivan Rychlik, Lenka Vlasatikova
In this study we compared the proteomes of macrophages and heterophils isolated from the spleen 4 days after intravenous infection of chickens with Salmonella Enteritidis. Heterophils were characterized by expression of MMP9, MRP126, LECT2, CATHL1, CATHL2, CATHL3, LYG2, LYZ and RSFR. Macrophages specifically expressed receptor proteins, e.g. MRC1L, LRP1, LGALS1, LRPAP1 and a DMBT1L. Following infection, heterophils decreased ALB and FN1, and released MMP9 to enable their translocation to the site of infection...
June 17, 2017: Veterinary Research
https://www.readbyqxmd.com/read/28623935/variation-in-susceptibility-of-different-breeds-of-sheep-to-mycobacterium-avium-subspecies-paratuberculosis-following-experimental-inoculation
#5
D J Begg, A C Purdie, K de Silva, N K Dhand, K M Plain, R J Whittington
Exposure to Mycobacterium avium subspecies paratuberculosis (MAP) does not always lead to Johne's disease. Understanding differences in disease susceptibility of individual animals is a key aspect to controlling mycobacterial diseases. This study was designed to examine the susceptibility or resistance of various breeds of sheep to MAP infection. Merino, Suffolk first cross Merino, Border Leicester, and Poll Dorset sheep were orally inoculated with MAP and monitored for 14 months. Clinical disease occurred more frequently in the Merino (42%) and Suffolk first cross Merino (36%) compared to the Border Leicester (12%) and Poll Dorset (11%) breeds...
June 17, 2017: Veterinary Research
https://www.readbyqxmd.com/read/28619040/helicobacter-suis-induces-changes-in-gastric-inflammation-and-acid-secretion-markers-in-pigs-of-different-ages
#6
C De Witte, B Devriendt, B Flahou, I Bosschem, R Ducatelle, A Smet, F Haesebrouck
Gastric mRNA expression of markers for acid secretion and inflammation and presence of gastric ulceration was studied in naturally Helicobacter suis-infected and non-infected 2-3 months old, 6-8 months old and adult pigs. In H. suis-infected 2-3 months old pigs, IL-8 and IL-1β transcript levels were upregulated in the pyloric gland zone, indicating an innate immune response. A similar response was demonstrated in the fundic gland zone of adult pigs, potentially due to a shift of H. suis colonization from the pyloric to the fundic gland zone...
June 15, 2017: Veterinary Research
https://www.readbyqxmd.com/read/28592320/infectivity-transmission-and-pathogenicity-of-h5-highly-pathogenic-avian-influenza-clade-2-3-4-4-h5n8-and-h5n2-united-states-index-viruses-in-pekin-ducks-and-chinese-geese
#7
Mary J Pantin-Jackwood, Mar Costa-Hurtado, Kateri Bertran, Eric DeJesus, Diane Smith, David E Swayne
In late 2014, a H5N8 highly pathogenic avian influenza (HPAI) virus, clade 2.3.4.4, spread by migratory waterfowl into North America reassorting with low pathogenicity AI viruses to produce a H5N2 HPAI virus. Since domestic waterfowl are common backyard poultry frequently in contact with wild waterfowl, the infectivity, transmissibility, and pathogenicity of the United States H5 HPAI index viruses (H5N8 and H5N2) was investigated in domestic ducks and geese. Ducks infected with the viruses had an increase in body temperature but no or mild clinical signs...
June 7, 2017: Veterinary Research
https://www.readbyqxmd.com/read/28549482/several-strains-one-disease-experimental-investigation-of-vibrio-aestuarianus-infection-parameters-in-the-pacific-oyster-crassostrea-gigas
#8
Marie-Agnès Travers, Delphine Tourbiez, Leïla Parizadeh, Philippe Haffner, Angélique Kozic-Djellouli, Mohamed Aboubaker, Marcel Koken, Lionel Dégremont, Coralie Lupo
This study investigated oyster infection dynamics by different strains of Vibrio aestuarianus isolated before and after the apparent re-emergence of this pathogen observed in France in 2011. We conducted experiments to compare minimal infective dose, lethal dose 50 and bacterial shedding for six V. aestuarianus strains. Whatever the strain used, mortality was induced in juvenile oysters by intramuscular injection and reached 90-100% of mortality within 5 days. Moreover, bacterial shedding was comparable among strains and reached its maximum after 20 h (≈10 EXP5 bacteria/mL/animal)...
May 26, 2017: Veterinary Research
https://www.readbyqxmd.com/read/28545558/from-the-epidemiology-of-hepatitis-e-virus-hev-within-the-swine-reservoir-to-public-health-risk-mitigation-strategies-a-comprehensive-review
#9
REVIEW
Morgane Salines, Mathieu Andraud, Nicolas Rose
Hepatitis E virus (HEV) is the causative agent of hepatitis E in humans, an emerging zoonosis mainly transmitted via food in developed countries and for which domestic pigs are recognised as the main reservoir. It therefore appears important to understand the features and drivers of HEV infection dynamics on pig farms in order to implement HEV surveillance programmes and to assess and manage public health risks. The authors have reviewed the international scientific literature on the epidemiological characteristics of HEV in swine populations...
May 25, 2017: Veterinary Research
https://www.readbyqxmd.com/read/28532492/innate-immune-responses-induced-by-the-saponin-adjuvant-matrix-m-in-specific-pathogen-free-pigs
#10
Viktor Ahlberg, Bernt Hjertner, Per Wallgren, Stina Hellman, Karin Lövgren Bengtsson, Caroline Fossum
Saponin-based adjuvants have been widely used to enhance humoral and cellular immune responses in many species, but their mode of action is not fully understood. A characterization of the porcine transcriptional response to Matrix-M was performed in vitro using lymphocytes, monocytes or monocyte-derived dendritic cells (MoDCs) and in vivo. The effect of Matrix-M was also evaluated in specific pathogen free (SPF) pigs exposed to conventionally reared pigs. The pro-inflammatory cytokine genes IL1B and CXCL8 were up-regulated in monocytes and lymphocytes after Matrix-M exposure...
May 22, 2017: Veterinary Research
https://www.readbyqxmd.com/read/28499403/surface-displaying-of-swine-igg1-fc-enhances-baculovirus-vectored-vaccine-efficacy-by-facilitating-viral-complement-escape-and-mammalian-cell-transduction
#11
Zehui Liu, Yangkun Liu, Yuanyuan Zhang, Yajuan Yang, Jingjing Ren, Xiaoying Zhang, Enqi Du
Baculovirus-mediated gene transfer has been developed as a vaccine design strategy against a number of diseases without apparent viral replication. However, it has been hampered by complement-dependent inactivation, thus hindering the in vivo application of baculovirus. A variety of approaches have been exploited to bypass the complement system in the serum. In this study, we constructed and screened a series of baculovirus vectors displaying complement interfering factors, of which a baculovirus vector displaying swine IgG1 Fc (pFc) showed the highest complement antagonism (75...
May 12, 2017: Veterinary Research
https://www.readbyqxmd.com/read/28472979/concurrent-infection-with-porcine-reproductive-and-respiratory-syndrome-virus-and-haemophilus-parasuis-in-two-types-of-porcine-macrophages-apoptosis-production-of-ros-and-formation-of-multinucleated-giant-cells
#12
Lenka Kavanová, Katarína Matiašková, Lenka Levá, Hana Štěpánová, Kateřina Nedbalcová, Ján Matiašovic, Martin Faldyna, Jiří Salát
Porcine reproductive and respiratory syndrome (PRRS) is one of the most significant and economically important infectious diseases affecting swine worldwide and can predispose pigs to secondary bacterial infections caused by, e.g. Haemophilus parasuis. The aim of the presented study was to compare susceptibility of two different types of macrophages which could be in contact with both pathogens during infection with PRRS virus (PRRSV) and in co-infection with H. parasuis. Alveolar macrophages (PAMs) as resident cells provide one of the first lines of defence against microbes invading lung tissue...
May 4, 2017: Veterinary Research
https://www.readbyqxmd.com/read/28454560/fecal-shedding-and-tissue-infections-demonstrate-transmission-of-mycobacterium-avium-subsp-paratuberculosis-in-group-housed-dairy-calves
#13
Caroline S Corbett, Jeroen De Buck, Karin Orsel, Herman W Barkema
Current Johne's disease control programs primarily focus on decreasing transmission of Mycobacterium avium subsp. paratuberculosis (MAP) from infectious adult cows to susceptible calves. However, potential transmission between calves is largely overlooked. The objective was to determine the extent of MAP infection in calves contact-exposed to infectious penmates. Thirty-two newborn Holstein-Friesian calves were grouped into 7 experimental groups of 4, consisting of 2 inoculated (IN) calves, and 2 contact-exposed (CE) calves, and 1 control pen with 4 non-exposed calves...
April 28, 2017: Veterinary Research
https://www.readbyqxmd.com/read/28424083/erratum-to-the-impact-of-co-infections-on-fish-a-review
#14
Mohamed H Kotob, Simon Menanteau-Ledouble, Gokhlesh Kumar, Mahmoud Abdelzaher, Mansour El-Matbouli
No abstract text is available yet for this article.
April 19, 2017: Veterinary Research
https://www.readbyqxmd.com/read/28412972/mammary-microbiota-of-dairy-ruminants-fact-or-fiction
#15
Pascal Rainard
Explorations of how the complex microbial communities that inhabit different body sites might contribute to health and disease have prompted research on the ways the harmonious relationship between a host and its microbiota could be used to keep animals healthy in their production conditions. In particular, there is a growing interest in the bacterial signatures that can be found in the milk of healthy or mastitic dairy cows. The concept of sterility of the healthy mammary gland of dairy ruminants has been challenged by the results of studies using bacterial DNA-based methodology...
April 17, 2017: Veterinary Research
https://www.readbyqxmd.com/read/28403902/phylodynamics-of-foot-and-mouth-disease-virus-o-panasia-in-vietnam-2010-2014
#16
Barbara Brito, Steven J Pauszek, Michael Eschbaumer, Carolina Stenfeldt, Helena C de Carvalho Ferreira, Le T Vu, Nguyen T Phuong, Bui H Hoang, Nguyen D Tho, Pham V Dong, Phan Q Minh, Ngo T Long, Donald P King, Nick J Knowles, Do H Dung, Luis L Rodriguez, Jonathan Arzt
Foot-and-mouth disease virus (FMDV) is endemic in Vietnam, a country that plays an important role in livestock trade within Southeast Asia. The large populations of FMDV-susceptible species in Vietnam are important components of food production and of the national livelihood. In this study, we investigated the phylogeny of FMDV O/PanAsia in Vietnam, reconstructing the virus' ancestral host species (pig, cattle or buffalo), clinical stage (subclinical carrier or clinically affected) and geographical location...
April 13, 2017: Veterinary Research
https://www.readbyqxmd.com/read/28403908/permissiveness-of-bovine-epithelial-cells-from-lung-intestine-placenta-and-udder-for-infection-with-coxiella-burnetii
#17
Katharina Sobotta, Katharina Bonkowski, Elisabeth Liebler-Tenorio, Pierre Germon, Pascal Rainard, Nina Hambruch, Christiane Pfarrer, Ilse D Jacobsen, Christian Menge
Ruminants are the main source of human infections with the obligate intracellular bacterium Coxiella (C.) burnetii. Infected animals shed high numbers of C. burnetii by milk, feces, and birth products. In goats, shedding by the latter route coincides with C. burnetii replication in epithelial (trophoblast) cells of the placenta, which led us to hypothesize that epithelial cells are generally implicated in replication and shedding of C. burnetii. We therefore aimed at analyzing the interactions of C. burnetii with epithelial cells of the bovine host (1) at the entry site (lung epithelium) which govern host immune responses and (2) in epithelial cells of gut, udder and placenta decisive for the quantity of pathogen excretion...
April 12, 2017: Veterinary Research
https://www.readbyqxmd.com/read/28399941/antimicrobial-potential-of-bacteriocins-in-poultry-and-swine-production
#18
REVIEW
Amel Ben Lagha, Bruno Haas, Marcelo Gottschalk, Daniel Grenier
The routine use of antibiotics in agriculture has contributed to an increase in drug-resistant bacterial pathogens in animals that can potentially be transmitted to humans. In 2000, the World Health Organization identified resistance to antibiotics as one of the most significant global threats to public health and recommended that the use of antibiotics as additives in animal feed be phased out or terminated, particularly those used to treat human infections. Research is currently being carried out to identify alternative antimicrobial compounds for use in animal production...
April 11, 2017: Veterinary Research
https://www.readbyqxmd.com/read/28399906/target-organs-for-lymphocystis-disease-virus-replication-in-gilthead-seabream-sparus-aurata
#19
Estefania J Valverde, Juan J Borrego, M Carmen Sarasquete, Juan B Ortiz-Delgado, Dolores Castro
The lymphocystis disease (LCD), the main viral pathology described in cultured gilthead seabream (Sparus aurata), is a self-limiting condition characterized by the appearance of hypertrophied fibroblasts (named lymphocysts) in the connective tissue of fish, primarily in the skin and fins. The causative agent of the disease is the Lymphocystis disease virus (LCDV), a member of the Iridoviridae family. In the present study, LCDV genome and transcripts were detected by real-time PCR in caudal fin, as well as in several internal organs, such as intestine, liver, spleen, kidney and brain, from asymptomatic, diseased and recovered gilthead seabream juveniles...
April 11, 2017: Veterinary Research
https://www.readbyqxmd.com/read/28388924/enhancing-the-toolbox-to-study-il-17a-in-cattle-and-sheep
#20
Sean R Wattegedera, Yolanda Corripio-Miyar, Yvonne Pang, David Frew, Tom N McNeilly, Javier Palarea-Albaladejo, Colin J McInnes, Jayne C Hope, Elizabeth J Glass, Gary Entrican
The development of methods to detect cytokine expression by T cell subsets in ruminants is fundamental to strategic development of new livestock vaccines for prevention of infectious diseases. It has been possible to detect T cell expression of IFN-γ, IL-4 and IL-10 in ruminants for many years but methods to detect expression of IL-17A are relatively limited. To address this gap in capability we have cloned bovine and ovine IL-17A cDNAs and expressed biologically-active recombinant proteins in Chinese Hamster Ovary (CHO) cells...
April 8, 2017: Veterinary Research
journal
journal
31381
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"