journal
MENU ▼
Read by QxMD icon Read
search

British Journal of Biomedical Science

journal
https://www.readbyqxmd.com/read/28709389/characterization-of-uropathogenic-e-coli-isolated-from-urinary-tract-infections-phylogenetic-typing-and-distribution-of-virulence-associated-traits
#1
A Salehzadeh, H Zamani
No abstract text is available yet for this article.
July 14, 2017: British Journal of Biomedical Science
https://www.readbyqxmd.com/read/28705139/anaplastic-lymphoma-kinase-alk-mutations-in-patients-with-adenocarcinoma-of-the-lung
#2
N Mohamad, P Jayalakshmi, A Rhodes, C-K Liam, J-L Tan, S Yousoof, P Rajadurai
BACKGROUND: Non-small cell lung cancer (NSCLC) is a major cause of cancer-related death. Approximately 2-16% of NSCLC patients with wild-type epidermal growth factor receptor (EGFR) harbour anaplastic lymphoma kinase (ALK) mutations. Both EGFR and ALK mutations occur most commonly in Asian patients with NSCLC. As targeted therapy is available for NSCLC patients with these mutations, it is important to establish reliable assays and testing strategies to identify those most likely to benefit from this therapy...
July 13, 2017: British Journal of Biomedical Science
https://www.readbyqxmd.com/read/28705056/combined-use-of-nuclear-phosphoprotein-c-myc-and-cellular-phosphoprotein-p53-for-hepatocellular-carcinoma-detection-in-high-risk-chronic-hepatitis-c-patients
#3
A M Attallah, M El-Far, M A Abdelrazek, M M Omran, A A Attallah, A A Elkhouly, H M Elkenawy, K Farid
BACKGROUND: Hepatocellular carcinoma (HCC) is a multistage process resulting from various genetic changes. We aimed to determine nuclear phosphoprotein c-Myc and cellular phosphoprotein p53 expression and to evaluate their importance in HCC diagnosis. METHODS: One hundred and twenty chronic hepatitis C (CHC) patients (60 non-HCC CHC patients and 60 HCC patients who had a single small (<5 cm) tumour) were recruited. The gene products of c-Myc and p53 were identified in liver tissues and serum samples using immunostaining, western blot and ELISA...
July 13, 2017: British Journal of Biomedical Science
https://www.readbyqxmd.com/read/28657840/therapeutic-warfarin-use-and-the-extrahepatic-functions-of-vitamin-k-dependent-proteins
#4
C J Donaldson, D J Harrington
The impact of warfarin therapy on the functions of extrahepatic vitamin K-dependent proteins (VKDP) is less clearly understood and less widely recognised in clinical practice than that on the hepatic counterparts (clotting factors II, VII, IX and X). Warfarin inhibits osteocalcin, an abundant extrahepatic VKDP involved in the mineralisation and maturation of bone and thus, primarily by this mechanism, may have an adverse effect on bone health. Whilst some studies do link warfarin use to an increase in osteoporosis and fracture risk others have not...
June 28, 2017: British Journal of Biomedical Science
https://www.readbyqxmd.com/read/28657490/uncertainty-of-measurement-in-andrology-uk-best-practice-guideline-from-the-association-of-biomedical-andrologists
#5
D Sanders, S Fensome-Rimmer, B Woodward
Uncertainty of measurement has become a paramount factor to consider in pathology. In the UK, consideration of uncertainty of measurement is mandatory for medical laboratories who apply to be accredited against ISO15189:2012 via the United Kingdom Accreditation Service. This guideline intends to help those working within diagnostic andrology to better understand the concept of uncertainty, and how it can be applied to semen analysis and post-vasectomy semen analysis. The various areas where uncertainty may exist are identified, and guidance is provided to minimise this uncertainty...
June 28, 2017: British Journal of Biomedical Science
https://www.readbyqxmd.com/read/28625099/toxicology-in-clinical-laboratories-challenging-times
#6
N W Brown
In recent years, there have been a number of significant developments in toxicology within clinical laboratories, both with the available instrumentation and in the range of compounds abused by the drug using communities. There have also been developments in the regulation of forensic science in the UK which may in time impact clinical toxicology. This review is designed to provide an update of these changes within toxicology to the more general pathology laboratory audience. For detailed information in specific areas, the reader is referred to the references in the text...
June 19, 2017: British Journal of Biomedical Science
https://www.readbyqxmd.com/read/28598259/sepp1-and-sep15-gene-polymorphisms-and-susceptibility-to-breast-cancer
#7
Samaneh Mohammaddoust, Zivar Salehi, Hamid Saeidi Saedi
No abstract text is available yet for this article.
June 9, 2017: British Journal of Biomedical Science
https://www.readbyqxmd.com/read/28589746/a-review-of-the-use-of-human-papilloma-virus-hpv-in-cervical-screening
#8
B Crossley, J Crossley
Using key words online databases were searched to identify relevant publications to review the use of Human papilloma virus (HPV) in cervical screening. The mode of cervical screening in the UK has been decided but implementation plans have yet to be announced. The protracted uncertainty surrounding the initial announcement to move to HPV primary screening together with the lack of a national steer has resulted in a flight of staff which threatens the provision of the current and future service. The transition will be a challenging time but analysis of data from more than 176,000 women has shown clear evidence of a reduction in the incidence of cancer where HPV testing is used...
June 7, 2017: British Journal of Biomedical Science
https://www.readbyqxmd.com/read/28571523/association-of-heterogenicity-of-helicobacter-pylori-cag-pathogenicity-island-with-peptic-ulcer-diseases-and-gastric-cancer
#9
J Khatoon, K N Prasad, R Prakash Rai, U C Ghoshal, N Krishnani
OBJECTIVE: To investigate the frequency and integrity of certain cag pathogenicity island genes (cagPAI) in Helicobacter pylori strains and their association with peptic ulcer disease (PUD) and gastric cancer. MATERIAL AND METHODS: We enrolled 240 adult patients [120 with functional dyspepsia (FD), 50 with PUD and 70 with gastric cancer] undergoing upper gastrointestinal endoscopy. H. pylori infection was diagnosed when either culture or any two of the three tests (rapid urease test, histopathology and specific ureA PCR) were positive...
June 2, 2017: British Journal of Biomedical Science
https://www.readbyqxmd.com/read/28537492/pleural-fluid-dna-integrity-index-as-a-diagnostic-marker-of-malignant-pleural-effusion
#10
A E Eltorgoman, Eae Badr, Yfae Kombr, M Yousif
No abstract text is available yet for this article.
May 24, 2017: British Journal of Biomedical Science
https://www.readbyqxmd.com/read/28521643/a-magnetic-nanoparticle-labeled-immunoassay-with-europium-and-samarium-for-simultaneous-quantification-of-serum-pepsinogen-i-and-ii
#11
J Fan, H Xiao, J Zhang, B Zhou, L Deng, Y Zhang, B Huang
OBJECTIVE: To develop a novel immunoassay for the simultaneous determination of serum pepsinogen I (PG I) and pepsinogen II (PG II) by combining established methods of time-resolved fluoroimmunoassay (TRFIA) and magnetic nanoparticles separation. MATERIALS AND METHODS: This new immunoassay method was characterised by immobilising primary antibodies on the surface of magnetic particles and labelled with stable fluorescent chelates of europium and samarium. RESULTS: Using magnetic nanoparticles, the TRFIA immunoassay exhibited broad dynamic assay ranges for PG I with detection limit of 0...
May 19, 2017: British Journal of Biomedical Science
https://www.readbyqxmd.com/read/28513273/the-clinical-value-of-vav3-in-peripheral-blood-for-predicting-lymphatic-metastasis-of-gastric-cancer
#12
B Tan, Y Li, C Wang, M Tan, L Fan, Q Zhao, D Wang, N Jia
BACKGROUND: Overexpression of Vav3, a gene involved in signal transduction, promotes invasion and inhibits apoptosis in several cancers. The clinical value of the protein product of this gene, Vav3, in the peripheral blood of gastric cancer patients is unknown. We hypothesised increased serum Vav3 that related to tissue levels and lymph node metastases. In addition, we further explored its clinical value in respect of linked molecules Rac-1, MMP-7 and ICAM-1 Methods: 120 gastric cancer patients who had radical surgery were enrolled...
May 17, 2017: British Journal of Biomedical Science
https://www.readbyqxmd.com/read/28504002/development-and-evaluation-of-a-novel-score-for-prediction-of-large-oesophageal-varices-in-patients-with-hepatitis-c-virus-induced-liver-cirrhosis
#13
K Farid, M M Omran, R E Farag, M M Arafa, T M Emran
OBJECTIVE: Variceal bleeding is one of the most common life-threatening complications of liver cirrhosis. This study aimed to develop and evaluate a predictive score, named Platelet count, Alpha fetoprotein (AFP) and Prothrombin-INR (PAP) for the prediction of large oesophageal varices and to compare PAP score with eight common liver fibrosis scores (AAR, APRI, GUCI, BRC score, Fibro-Alfa, FIB4, Lok and Fibro-Q) in patients with hepatitis C virus (HCV) induced liver cirrhosis. METHODS: A total of 277 patients with HCV-induced liver cirrhosis were evaluated by upper gastrointestinal endoscopy for presence of varices...
May 15, 2017: British Journal of Biomedical Science
https://www.readbyqxmd.com/read/28493763/fluorescent-pcr-detection-of-meca-in-drug-resistant-mrsa-a-methodological-study
#14
Y Cao, Y Hao, D Yang, B Pang, L Wang
No abstract text is available yet for this article.
May 11, 2017: British Journal of Biomedical Science
https://www.readbyqxmd.com/read/28664819/referees-2016
#15
(no author information available yet)
No abstract text is available yet for this article.
July 2017: British Journal of Biomedical Science
https://www.readbyqxmd.com/read/28664818/erratum
#16
(no author information available yet)
No abstract text is available yet for this article.
July 2017: British Journal of Biomedical Science
https://www.readbyqxmd.com/read/28367740/mir-199a-3p-downregulation-in-thyroid-tissues-is-associated-with-invasion-and-metastasis-of-papillary-thyroid-carcinoma
#17
Chengbiao Liu, Meiling Xing, Liping Wang, Kejun Zhang
BACKGROUND AND AIMS: miR-199a-3p may play an important role in tumour inhibition. The aim of the present study was to determine any link between miR-199a-3p expression in thyroid tissues and clinicopathologic features, as well as to assess potential usefulness of miR-199a-3p in prediction for invasion and metastasis of papillary thyroid carcinoma (PTC). METHODS: A total of 188 tissue samples (136 PTCs, 52 normal thyroid tissue) were collected. We measured the levels of miR-199a-3p with quantitative reverse-transcriptase PCR (RT-qPCR) in all subjects...
April 2017: British Journal of Biomedical Science
https://www.readbyqxmd.com/read/28367739/towards-understanding-clinical-campylobacter-infection-and-its-transmission-time-for-a-different-approach
#18
E Casey, E Fitzgerald, B Lucey
Campylobacter spp. are among the most commonly diagnosed causes of human infection. Methods for detection of the 29 campylobacter species have mainly focused on cultivation of the thermophilic species. More than 99% of clinical campylobacter isolates notified in the UK in the recent past have been from faecal samples and associated with gastroenteritis. Campylobacter enteritis notifications in temperate zones show a seasonal increase during the summer months with a sharp decrease in the winter months, a pattern which remains incompletely understood...
April 2017: British Journal of Biomedical Science
https://www.readbyqxmd.com/read/28367738/comparison-of-the-fast-track-diagnostics-respiratory-21-and-seegene-allplex-multiplex-polymerase-chain-reaction-assays-for-the-detection-of-respiratory-viruses
#19
Kevin Barratt, Trevor P Anderson, Jennifer A Fahey, Lance C Jennings, Anja M Werno, David R Murdoch
BACKGROUND: Real-time multiplex PCR assays are increasingly used for respiratory virus detection, and offer automated analysis in a closed tube system, but they have the disadvantage of low-throughput due to multiplexing limitations. In this study, the established fast-track respiratory 21 assay (FTD) (fast-track diagnostics, Junglinster Luxembourg) was compared to the new Seegene Allplex assay (Seegene) (Seegene Inc. Seoul, Korea) which offers greater multiplexing as multiple targets can be detected in each fluorescence channel...
April 2017: British Journal of Biomedical Science
https://www.readbyqxmd.com/read/28367737/circulating-levels-of-collagen-iii-and-mmp-1-in-patients-with-chronic-hepatitis-c-co-infected-with-hepatitis-b-virus
#20
Abdelfattah M Attallah, Mohamed El-Far, Mohamed F Ghaly, Mohamed M Omran, Mohamed S Albannan, Ahmed A Attallah, Tarek M Shoghey, Mohamed M Atrees, Mohamed S Elbendary, Khaled Farid
BACKGROUND: There is controversial data in the literature about the characteristics and features of dual hepatitis B and hepatitis C infection. This work is concerned with estimating the extent to which HBV could influence circulating levels of hepatitis C viral nonstructural-4 (HCV-NS4) in addition to some direct fibrosis markers in chronic hepatitis C. METHODS: Thirty-eight HCV mono-infected and 87 HCV/HBV co-infected patients constituted this study. Western-blot and ELISA were used for identifying HCV-NS4, hepatitis B surface antigen (HBsAg), collagen III and matrixmetalloproteinase-1 (MMP-1) in patients' sera...
April 2017: British Journal of Biomedical Science
journal
journal
31375
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"