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Hypertension Research: Official Journal of the Japanese Society of Hypertension

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https://www.readbyqxmd.com/read/28878301/epa-dha-6-1-prevents-angiotensin-ii-induced-hypertension-and-endothelial-dysfunction-in-rats-role-of-nadph-oxidase-and-cox-derived-oxidative-stress
#1
Zahid Rasul Niazi, Grazielle C Silva, Thais Porto Ribeiro, Antonio J León-González, Mohamad Kassem, Abdur Mirajkar, Azhar Alvi, Malak Abbas, Faraj Zgheel, Valérie B Schini-Kerth, Cyril Auger
Eicosapentaenoic acid:docosahexaenoic acid (EPA:DHA) 6:1, an omega-3 polyunsaturated fatty acid formulation, has been shown to induce a sustained formation of endothelial nitric oxide (NO) synthase-derived NO, a major vasoprotective factor. This study examined whether chronic intake of EPA:DHA 6:1 prevents hypertension and endothelial dysfunction induced by angiotensin II (Ang II) in rats. Male Wister rats received orally corn oil or EPA:DHA 6:1 (500 mg kg(-1) per day) before chronic infusion of Ang II (0...
September 7, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28878300/white-coat-and-masked-hypertension-are-associated-with-albuminuria-in-a-general-population-the-hisayama-study
#2
Jun Hata, Masayo Fukuhara, Satoko Sakata, Hisatomi Arima, Yoichiro Hirakawa, Koji Yonemoto, Naoko Mukai, Takanari Kitazono, Yutaka Kiyohara, Toshiharu Ninomiya
Epidemiological and clinical studies have investigated the influence of hypertension on chronic kidney disease (CKD), but limited data are available for the associations of white-coat hypertension (WCHT), masked hypertension (MHT) and sustained hypertension (SHT) with kidney dysfunction in general populations. We examined the associations of these types of hypertension with CKD (albuminuria and reduction in estimated glomerular filtration rate (eGFR)) in a cross-sectional survey of 2974 community-dwelling Japanese aged ⩾40 years...
September 7, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28878299/a-study-on-clinicoradiological-characteristics-and-pregnancy-outcomes-of-reversible-posterior-leukoencephalopathy-syndrome-in-preeclampsia-or-eclampsia
#3
Xiaobo Fang, Yanling Liang, Dunjin Chen, Fang He, Jia Chen, Fami Huang
Reversible posterior leukoencephalopathy syndrome (RPLS) is a critical maternal complication in preeclampsia or eclampsia during pregnancy. However, studies regarding the clinicoradiological and outcome differences between RPLS and non-RPLS pregnancies are scarce. We aimed to explore the incidence of RPLS, and summarize the clinicoradiological characteristics and pregnancy outcomes. We consecutively collected a total of 100 patients who were diagnosed with preeclampsia or eclampsia, and examined via magnetic resonance imaging (MRI) among 21 872 women between 2013 and 2016...
September 7, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28878298/upregulation-of-cathepsin-c-expression-contributes-to-endothelial-chymase-activation-in-preeclampsia
#4
Yang Gu, David F Lewis, J Steven Alexander, Yuping Wang
Chymase is an ACE (angiotensin-converting enzyme)-independent angiotensin II-forming enzyme whose expression is increased in the maternal vascular endothelium in preeclampsia. However, mechanisms underlying chymase activation in preeclampsia remain unclear. Cathepsin C is a key enzyme in the activation of several serine proteases including chymase. In this study, we determined whether increased cathepsin C expression/activity might be responsible for the upregulation of chymase expression in preeclampsia. Maternal vascular cathepsin C, chymase and ACE expression were examined through immunohistochemical staining of subcutaneous fat tissue sections of normal and preeclamptic pregnant women...
September 7, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28855666/plasma-thrombin-cleaved-osteopontin-as-a-potential-biomarker-of-acute-atherothrombotic-ischemic-stroke-comments-on-data-sparsity
#5
Erfan Ayubi, Saeid Safiri
No abstract text is available yet for this article.
August 31, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28814786/new-approach-to-arterial-stiffness-bp-independent-local-carotid-stiffness
#6
Kazuki Shiina, Hirofumi Tomiyama
No abstract text is available yet for this article.
August 17, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28769100/resistance-training-alone-reduces-systolic-and-diastolic-blood-pressure-in-prehypertensive-and-hypertensive-individuals-meta-analysis
#7
Evitom Corrêa de Sousa, Odilon Abrahin, Ana Lorena Lima Ferreira, Rejane Pequeno Rodrigues, Erik Artur Cortinhas Alves, Rodolfo Paula Vieira
The purpose of this study was to evaluate the effects of resistance training alone on the systolic and diastolic blood pressure in prehypertensive and hypertensive individuals. Our meta-analysis, followed the guidelines of PRISMA. The search for articles was realized by November 2016 using the following electronic databases: BIREME, PubMed, Cochrane Library, LILACS and SciELO and a search strategy that included the combination of titles of medical affairs and terms of free text to the key concepts: 'hypertension' 'hypertensive', 'prehypertensive', 'resistance training', 'strength training', and 'weight-lifting'...
August 3, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28701740/comprehensive-risk-management-for-the-prevention-of-cerebro-cardiovascular-diseases-in-japan
#8
(no author information available yet)
No abstract text is available yet for this article.
July 13, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28701738/increased-nocturnal-blood-pressure-variability-is-associated-with-renal-arteriolar-hyalinosis-in-normotensive-patients-with-iga-nephropathy
#9
Shinsuke Isobe, Naro Ohashi, Sayaka Ishigaki, Naoko Tsuji, Takayuki Tsuji, Akihiko Kato, Hideo Yasuda
Abnormal blood pressure (BP) variability (BPV), occurring as beat-to-beat, 24 h, and day-to-day fluctuations, is related to target organ damage. However, the associations between abnormal BPV and renal structural changes have not been clearly investigated. We evaluated the day time and night time BP s.d. and average real variability (ARV), which reflected short-term BPV, the night time to day time (N/D) ratio of systolic BP (SBP), and the 7-day BPV, in 29 normotensive IgA nephropathy (IgAN) patients. We further compared the results with renal structural changes...
July 13, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28680167/efficiency-and-specificity-of-raas-inhibitors-in-cardiovascular-diseases-how-to-achieve-better-end-organ-protection
#10
REVIEW
Ali Nehme, Kazem Zibara
RAAS, a major pharmacological target in cardiovascular medicine, is inhibited by pharmacological classes including angiotensin converting enzyme (ACE) inhibitors (ACEIs), angiotensin-II type 1 blockers (ARBs) and aldosterone receptors antagonists, in addition to the recently introduced direct renin inhibitors (DRIs). However, currently used RAAS inhibitors still cannot achieve their desired effects and are associated with certain drawbacks, such as adverse side effects, incomplete blockage of the system and poor end-organ protection...
July 6, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28701739/hypertension-with-diabetes-mellitus-significance-from-an-epidemiological-perspective-for-japanese
#11
Yukako Tatsumi, Takayoshi Ohkubo
The prevalence of both hypertension and diabetes mellitus is increasing worldwide. Both diseases lead to severe complications such as cardiovascular and chronic kidney diseases, which increase the risk of death over a long period of time. Therefore, the prevention and aggravation of hypertension and diabetes mellitus are major challenges. Because few review articles have focused on the epidemiological perspective of hypertension and diabetes mellitus, we reviewed major observational studies mainly from Japan and from Western countries that have reported on the prevalence of hypertension and diabetes mellitus, the binominal risk of hypertension and diabetes mellitus, and the risk of their coexistence...
September 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28381875/masked-uncontrolled-hypertension-in-patients-on-maintenance-hemodialysis
#12
Wenjin Liu, Liang Wang, Zhuxing Sun, Xiurong Li, Jianmei Zhou, Chaoqing Gao, Hong Chu, Wei Fan, Youwei Bai, Junwei Yang
Masked uncontrolled hypertension (MUCH) has been proven to be associated with increased cardiovascular risk in the general population. We performed the current analysis to determine its prevalence in dialysis patients and its association with pulse wave velocity (PWV). From 368 participants of another cohort study, we selected 145 subjects with controlled predialysis blood pressure (BP). All subjects underwent ambulatory BP monitoring and PWV measurement. MUCH was defined as controlled predialysis BP with daytime BP⩾135/85 mm Hg (definition-1); total ambulatory BP⩾130/80 mm Hg (definition-2); and either daytime BP⩾135/85 mm Hg or nighttime BP⩾120/70 mm Hg (definition-3)...
September 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28381874/antihypertensive-medication-and-risk-of-kidney-stones-a-canadian-wake-up-call
#13
Daniel G Fuster
No abstract text is available yet for this article.
September 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28381872/impact-of-mild-to-moderate-alcohol-consumption-and-smoking-on-kidney-function
#14
Naoki Nakagawa, Naoyuki Hasebe
No abstract text is available yet for this article.
September 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28381870/cardiovascular-calcification-and-subcortical-bone-demineralization-in-hypertension
#15
Chiara Cirillo, Giancarlo Bilancio, Francesco Natale, Claudia Concilio, Maria Giovanna Russo, Paolo Calabrò, Massimo Cirillo
The present study investigated cardiovascular calcification, peripheral bone mineral density (BMD), and lab indices in hypertensive patients aged 55-74 years without severe kidney dysfunction. Cardiovascular calcification was investigated by ultrasound examinations at eight sites: aortic valve, left and right common carotid artery, left and right carotid artery bifurcation, left and right internal carotid artery, and abdominal aorta. The presence/absence of calcification at each site was coded as 1/0, respectively, for the calculation of a cumulative score...
September 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28381869/does-the-pathophysiology-of-heart-failure-prime-the-incidence-of-cancer
#16
Mari Sakamoto, Takuya Hasegawa, Masanori Asakura, Hideaki Kanzaki, Hiroyuki Takahama, Makoto Amaki, Naoki Mochizuki, Toshihisa Anzai, Toshimitsu Hamasaki, Masafumi Kitakaze
Both chronic heart failure (CHF) and cancer are among the most frequent causes of death in developed countries. Given that CHF activates neurohumoral factors, such as cytokines, the pathophysiology of CHF could prime the onset or progression of cancer. We consecutively enrolled 5238 patients with CHF who had been hospitalized in the Department of Cardiovascular Medicine in our institute between 2001 and 2013. We followed these patients until April 2015. We examined the cohort of patients from our hospital and compared it with a control cohort derived from the 2008 cancer database 'Monitoring of Cancer Incidence in Japan' from the National Cancer Center, Japan...
September 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28356575/ejection-time-influence-of-hemodynamics-and-site-of-measurement-in-the-arterial-tree
#17
Yurie Obata, Maki Mizogami, Sarabdeep Singh, Daniel Nyhan, Dan E Berkowitz, Jochen Steppan, Viachaslau Barodka
The left ventricular ejection time is routinely measured from a peripheral arterial waveform. However, the arterial waveform undergoes constant transformation as the pulse wave propagates along the arterial tree. Our goal was to determine if the left ventricular ejection time measured peripherally in the arterial tree accurately reflected the ejection time measured through the aortic valve. Moreover, we examined/accessed the modulating influence of hemodynamics on ejection time measurements. Continuous wave Doppler waveform images through the aortic valve and the simultaneously obtained radial artery pressure waveforms were analyzed to determine central and peripheral ejection times, respectively...
September 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28356574/comments-on-the-associations-of-systolic-and-diastolic-blood-pressure-night-to-day-ratios-with-atherosclerotic-cardiovascular-diseases
#18
Saeid Safiri, Erfan Ayubi
No abstract text is available yet for this article.
September 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28331215/description-of-a-strong-relationship-among-total-cell-free-dna-levels-ldh-values-ast-values-and-platelet-count-in-patients-with-hellp-syndrome
#19
Pablo Stiefel, María L Miranda, Hada Macher, Luis M Beltran-Romero, Rocio Muñoz-Hernandez
No abstract text is available yet for this article.
September 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28331214/antihypertensive-medications-and-the-risk-of-kidney-stones-in-older-adults-a-retrospective-cohort-study
#20
R Todd Alexander, Eric McArthur, Racquel Jandoc, Blayne Welk, Jade S Hayward, Arsh K Jain, Branko Braam, Veit Flockerzi, Amit X Garg, Robert Ross Quinn
Antihypertensives are widely prescribed and could influence kidney stone risk by altering urinary calcium excretion. However, the impact of different classes of antihypertensives on kidney stone risk is unknown. To assess this impact, we conducted a retrospective, population-based cohort study using linked health administrative databases. Individuals aged >65 years who initiated one of the four antihypertensive classes (that is, angiotensin-converting enzyme inhibitors (ACEis)/angiotensin receptor blockers (ARBs), beta-blockers, calcium channel blockers or thiazide diuretics) were included...
September 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
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