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Hypertension Research: Official Journal of the Japanese Society of Hypertension

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https://www.readbyqxmd.com/read/28566737/sex-specific-cardiopulmonary-exercise-testing-parameters-as-predictors-in-patients-with-idiopathic-pulmonary-arterial-hypertension
#1
Ping Yuan, Hui-Juan Ni, Tian-Xiang Chen, Bigyan Pudasaini, Rong Jiang, Hui Liu, Qin-Hua Zhao, Lan Wang, Su-Gang Gong, Jin-Ming Liu
Cardiopulmonary exercise testing (CPET) has been used for prognosis in idiopathic pulmonary arterial hypertension (IPAH). We explored whether sex differences had an impact on prognostic assessments of CPET in IPAH. Data were retrieved from 21 male and 36 female incident IPAH patients who underwent both right heart catheterization and CPET from 2010 to 2016 at Shanghai Pulmonary Hospital. Cox proportional hazards analysis was used to assess the prognostic value of CPET. The mean duration of follow-up was 22±15 months...
June 1, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28490753/wbc-count-predicts-the-risk-of-new-onset-peripheral-arterial-disease-in-a-chinese-community-based-population
#2
Yuxi Li, Fangfang Fan, Jia Jia, Jianping Li, Yong Huo, Yan Zhang
This longitudinal cohort study investigated whether peripheral WBC counts could predict peripheral arterial disease (PAD) incidence after a 2.3-year follow-up in a Chinese community-based population without PAD at baseline. A total of 3555 Chinese subjects without fever and PAD at baseline from an atherosclerosis cohort were included in our analysis. The ankle brachial index (ABI) was measured, and PAD was defined as an ABI <0.9. Multivariate regression models were used to evaluate the association of WBC count and new-onset PAD...
May 11, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28446809/blood-pressure-management-in-patients-with-type-2-diabetes-mellitus
#3
Hisashi Kai
Hypertension aggravates macrovascular and microvascular diseases and mortality in patients with type 2 diabetes mellitus (T2DM). The current Japanese Society of Hypertension Guidelines of the Management of Hypertension (JSH 2014) recommends that antihypertensive medication should be initiated concomitantly with lifestyle modification when blood pressure (BP) is ⩾130/80 mm Hg and that target levels of office and home BP should be <130/80 mm Hg and <125/75 mm Hg, respectively, in T2DM patients...
April 27, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28446808/possible-combinatorial-effects-of-current-smoking-and-alcohol-intake-on-chronic-kidney-disease-in-a-japanese-nationwide-cross-sectional-survey
#4
Kouichi Tamura, Toru Dejima, Yukiko Morita, Satoshi Hirade, Hiromichi Wakui
No abstract text is available yet for this article.
April 27, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28446807/increased-blood-pressure-in-nesfatin-nuclebindin-2-transgenic-mice
#5
Yusaku Mori, Hiroyuki Shimizu, Hideki Kushima, Munenori Hiromura, Michishige Terasaki, Michitaka Tanaka, Aya Osaki, Tsutomu Hirano
Nesfatin/nucleobindin-2 (nesf/NUCB2), a precursor of the anorexigenic protein nesfatin-1, is selectively expressed in the hypothalamic nuclei, which are central to the regulation of the autonomic nervous system. The present study sought to investigate the involvement of nesf/NUCB2 in the regulation of blood pressure and ingestive behavior, by using nesf/NUCB2-transgenic (Tg) mice. Blood pressure and heart rates were measured under conscious and unconscious conditions. Twenty-four-hour water intake and urine volume of male nesf/NUCB2-Tg mice and their littermates in metabolic cages were measured...
April 27, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28446806/response-to-yatabe-et-al
#6
Tomohiro Hanazawa, Kei Asayama, Yutaka Imai, Takayoshi Ohkubo
No abstract text is available yet for this article.
April 27, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28446805/biomarkers-for-right-sided-heart-failure
#7
Masayuki Tanemoto
No abstract text is available yet for this article.
April 27, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28446804/the-effects-of-increasing-calcium-channel-blocker-dose-vs-adding-a-diuretic-to-treatment-regimens-for-patients-with-uncontrolled-hypertension
#8
Shigemasa Tani, Kei Asayama, Koji Oiwa, Shinsuke Harasawa, Katsuaki Okubo, Atsuhiko Takahashi, Ayumi Tanabe, Takayoshi Ohkubo, Atsushi Hirayama, Toshio Kushiro
In patients with insufficient blood pressure (BP) control, despite using a combination regimen containing an angiotensin receptor blocker and a calcium channel blocker (CCB), whether a greater dose of CCB or adding a diuretic is more effective at lowering BP remains unclear. We conducted a multicenter randomized clinical trial to compare the efficacy of switching from the daily administration of a single-pill fixed-dose combination of irbesartan (100 mg) and amlodipine (5 mg) to irbesartan (100 mg) with an increased dose of amlodipine (10 mg) (HD group, n=62) or irbesartan (100 mg) and amlodipine (5 mg) with 1 mg of indapamide (D group, n=63) in patients with poorly controlled hypertension...
April 27, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28446803/observational-study-and-participant-level-meta-analysis-on-antihypertensive-drug-treatment-related-cardiovascular-risk
#9
REVIEW
Kei Asayama
Although antihypertensive therapy reduces cardiovascular risk, individuals who are treated with antihypertensive medication generally have a worse prognosis for cardiovascular disease than untreated people. We recently evaluated the impact of conventional blood pressure level based on two Japanese individual participant databases and found that conventional blood pressure at baseline was not or was weakly associated with cardiovascular events among patients under antihypertensive drug medication. In the general population in Ohasama and the Hypertension Objective Treatment Based on Measurement by Electrical Devices of Blood Pressures study, self-measured home blood pressure significantly predicted cardiovascular outcomes in patients under antihypertensive treatment...
April 27, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28446802/reply-to-use-of-serum-fibroblast-growth-factor-23-vs-plasma-b-type-natriuretic-peptide-levels-in-assessing-the-pathophysiology-of-patients-with-heart-failure
#10
Miki Imazu, Hiroyuki Takahama, Masafumi Kitakaze
No abstract text is available yet for this article.
April 27, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28446801/genetic-susceptibility-to-salt-sensitive-hypertension-in-a-han-chinese-population-a-validation-study-of-candidate-genes
#11
Zheng Liu, Han Qi, Bin Liu, Kuo Liu, Jingjing Wu, Han Cao, Jie Zhang, Yuxiang Yan, Yan He, Ling Zhang
Salt-sensitive hypertension is a complex disease associated with genetic factors. This study aimed to identify the association between 29 candidate single-nucleotide polymorphisms and salt-sensitive hypertension in a Han Chinese population. Sixty-three participants with salt-sensitive hypertension and 279 controls with salt-resistant hypertension were recruited. A modified Sullivan's acute oral saline load and diuresis shrinkage test was used to detect blood pressure salt sensitivity. Lifestyle risk factors were obtained via a questionnaire...
April 27, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28424510/the-effect-of-slow-loaded-breathing-training-on-the-blood-pressure-response-to-handgrip-exercise-in-patients-with-isolated-systolic-hypertension
#12
Chulee Ubolsakka-Jones, Benjarat Sangthong, Wilaiwan Khrisanapant, David A Jones
Isolated systolic hypertension (ISH) is the most common form of hypertension in older people. It is characterized by increased resting systolic blood pressure (sBP) and increased sBP in response to exercise. It has previously been shown that slow breathing training reduces resting sBP, and the objective of the present study was to determine whether it also reduced the blood pressure response to static handgrip exercise. ISH patients aged between 60 and 74 years were randomly divided into a control group (10 subjects, 4 of which were male) that breathed normally and a trained group (10 subjects, 4 of which were male) that trained daily for 8 weeks by slow breathing against an inspiratory resistance of 18 cmH2O...
April 20, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28405012/accumulation-of-evidence-regarding-home-blood-pressure-during-pregnancy-is-necessary
#13
Hirohito Metoki, Michihiro Satoh, Takahisa Murakami
No abstract text is available yet for this article.
April 13, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28381875/masked-uncontrolled-hypertension-in-patients-on-maintenance-hemodialysis
#14
Wenjin Liu, Liang Wang, Zhuxing Sun, Xiurong Li, Jianmei Zhou, Chaoqing Gao, Hong Chu, Wei Fan, Youwei Bai, Junwei Yang
Masked uncontrolled hypertension (MUCH) has been proven to be associated with increased cardiovascular risk in the general population. We performed the current analysis to determine its prevalence in dialysis patients and its association with pulse wave velocity (PWV). From 368 participants of another cohort study, we selected 145 subjects with controlled predialysis blood pressure (BP). All subjects underwent ambulatory BP monitoring and PWV measurement. MUCH was defined as controlled predialysis BP with daytime BP⩾135/85 mm Hg (definition-1); total ambulatory BP⩾130/80 mm Hg (definition-2); and either daytime BP⩾135/85 mm Hg or nighttime BP⩾120/70 mm Hg (definition-3)...
April 6, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28381874/antihypertensive-medication-and-risk-of-kidney-stones-a-canadian-wake-up-call
#15
Daniel G Fuster
No abstract text is available yet for this article.
April 6, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28381872/impact-of-mild-to-moderate-alcohol-consumption-and-smoking-on-kidney-function
#16
Naoki Nakagawa, Naoyuki Hasebe
No abstract text is available yet for this article.
April 6, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28381871/novel-insight-into-arrhythmogenic-remodeling-a-target-for-reversal
#17
Sandor Batkai, Ariana Foinquinos
No abstract text is available yet for this article.
April 6, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28381870/cardiovascular-calcification-and-subcortical-bone-demineralization-in-hypertension
#18
Chiara Cirillo, Giancarlo Bilancio, Francesco Natale, Claudia Concilio, Maria Giovanna Russo, Paolo Calabrò, Massimo Cirillo
The present study investigated cardiovascular calcification, peripheral bone mineral density (BMD), and lab indices in hypertensive patients aged 55-74 years without severe kidney dysfunction. Cardiovascular calcification was investigated by ultrasound examinations at eight sites: aortic valve, left and right common carotid artery, left and right carotid artery bifurcation, left and right internal carotid artery, and abdominal aorta. The presence/absence of calcification at each site was coded as 1/0, respectively, for the calculation of a cumulative score...
April 6, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28381869/does-the-pathophysiology-of-heart-failure-prime-the-incidence-of-cancer
#19
Mari Sakamoto, Takuya Hasegawa, Masanori Asakura, Hideaki Kanzaki, Hiroyuki Takahama, Makoto Amaki, Naoki Mochizuki, Toshihisa Anzai, Toshimitsu Hamasaki, Masafumi Kitakaze
Both chronic heart failure (CHF) and cancer are among the most frequent causes of death in developed countries. Given that CHF activates neurohumoral factors, such as cytokines, the pathophysiology of CHF could prime the onset or progression of cancer. We consecutively enrolled 5238 patients with CHF who had been hospitalized in the Department of Cardiovascular Medicine in our institute between 2001 and 2013. We followed these patients until April 2015. We examined the cohort of patients from our hospital and compared it with a control cohort derived from the 2008 cancer database 'Monitoring of Cancer Incidence in Japan' from the National Cancer Center, Japan...
April 6, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28381873/from-apelin-to-exercise-emerging-therapies-for-management-of-hypertension-in-pregnancy
#20
Jeffrey S Gilbert
Studies over the last couple of decades have provided exciting new insights into mechanisms underlying the pathogenesis of preeclampsia. In addition, several novel and innovative molecules and ideas for management of the syndrome have also come forth. While our basic understanding of the initiating events of preeclampsia continues to be placental ischemia/hypoxia stimulating the release of a variety of factors from the placenta that act on the cardiovascular and renal systems, the number of candidate pathways for intervention continues to increase...
June 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
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