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Seizure: the Journal of the British Epilepsy Association

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https://www.readbyqxmd.com/read/30639977/association-between-epilepsy-and-risk-of-sexual-dysfunction-a-meta-analysis
#1
REVIEW
Shankun Zhao, Zhen Tang, Qiang Xie, Jiamin Wang, Lianmin Luo, Yangzhou Liu, Zhiguo Zhu, Jintai Luo, Zhigang Zhao
PURPOSE: Sexual functioning is an important factor influencing quality of life. Mounting evidence suggests that both male and female patients with epilepsy (PWE) have an increased risk of developing sexual dysfunction (SD). The aim of this meta-analysis was to quantify the association between epilepsy and the risk of SD. METHODS: PubMed, Embase, and Cochrane Library database were systematically searched to identify the pertinent studies focusing on the association between epilepsy and SD...
January 10, 2019: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/30612077/early-infantile-scn1a-epileptic-encephalopathy-expanding-the-genotype-phenotype-correlations
#2
Carlotta Spagnoli, Daniele Frattini, Susanna Rizzi, Grazia Gabriella Salerno, Carlo Fusco
No abstract text is available yet for this article.
January 2, 2019: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/30612076/factors-predicting-uncontrolled-seizures-in-epilepsy-with-auditory-features
#3
Lin Zhang, Xi Zhu, Xiaoyi Zou, Lei Chen
PURPOSE: To analyse the factors predicting uncontrolled seizures in epilepsy with auditory features (EAF). METHODS: We analysed individual data from EAF patients who were previously reported. Two authors independently reviewed the titles and abstracts identified and extracted data from each eligible study using a standardized form. The outcome measure was uncontrolled seizures. The odds ratio (OR) and 95% confidence interval (CI) were used. RESULTS: A total of 27 studies including 181 patients with familial and sporadic EAF met our inclusion criteria...
December 29, 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/30611009/oral-health-and-dental-status-in-people-with-epilepsy-in-rural-china
#4
Mengjie Wang, Ding Ding, Qing Zhang, Guoxing Zhu, Yan Ge, Bin Yang, Taiping Wang, Patrick Kwan, Wenzhi Wang, Zhen Hong, Josemir W Sander
PURPOSE: We evaluated the oral health and dental status of people with epilepsy, and their relationship to seizure frequency, in a community cohort in rural China. METHODS: A cross-sectional study of people with epilepsy was carried out in areas in Henan, Shanxi and Ningxia provinces of China. All participants underwent a specially designed "Oral health and Dental status Questionnaire". Univariate and multivariate analyses were used to explore the relationships between seizure frequency and oral health and dental status...
December 28, 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/30611010/tonic-clonic-seizure-detection-using-accelerometry-based-wearable-sensors-a-prospective-video-eeg-controlled-study
#5
Dongni Johansson, Fredrik Ohlsson, David Krýsl, Bertil Rydenhag, Madeleine Czarnecki, Niclas Gustafsson, Jan Wipenmyr, Tomas McKelvey, Kristina Malmgren
PURPOSE: The aim of this prospective, video-electroencephalography (video-EEG) controlled study was to evaluate the performance of an accelerometry-based wearable system to detect tonic-clonic seizures (TCSs) and to investigate the accuracy of different seizure detection algorithms using separate training and test data sets. METHODS: Seventy-five epilepsy surgery candidates undergoing video-EEG monitoring were included. The patients wore one three-axis accelerometer on each wrist during video-EEG...
December 27, 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/30641413/effects-of-antiepileptic-drugs-on-dynamic-thiol-disulphide-homeostasis-in-children-with-idiopathic-epilepsy
#6
Ebru Arhan, Aysegül Nese Citak Kurt, Salim Neselioglu, Ozcan Yerel, Habibe Koç Uçar, Kursad Aydin, Ayse Serdaroglu
PURPOSE: Anti-epileptic drugs have been widely used in children with epilepsy. Although several studies have investigated the role of oxidative stress and the effects of antiepileptic drugs on several oxidative markers in epilepsy, adequate information is not available on this issue. This study aimed to investigate the changes in thiol disulphide homeostasis in children with epilepsy under two commonly prescribed AED monotherapies, carbamazepine and valproic acid. METHODS: A hundred and one children with epilepsy using valproic acid or carbamazepine and 58 healthy children were included in this study...
December 26, 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/30605881/perisylvian-epileptic-network-revisited
#7
REVIEW
Péter Halász, Anna Kelemen, Bea Rosdy, György Rásonyi, Béla Clemens, Anna Szűcs
We overview here the new data about the epileptic spectrum disorders within the frame of perisylvian epileptic network since our first trial to synthetize knowledge about this system epilepsy (Halász et al., 2005). We found evidences for a continual features relating together syndromes constituting this spectrum disorder in several fields: in sharing genetic origin, in common perisylvian human communication circuitry, in NREM sleep related potentiation of interictal epileptiform discharges of the centro-temporal spike phenomenon and in the discharge related cognitive impairment, reflecting functional deficits in human communication abilities...
December 21, 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/30616221/aberrant-epileptic-seizure-identification-a-computer-vision-perspective
#8
David Ahmedt-Aristizabal, Clinton Fookes, Simon Denman, Kien Nguyen, Sridha Sridharan, Sasha Dionisio
PURPOSE: The recent explosion of artificial intelligence techniques in video analytics has highlighted the clinical relevance in capturing and quantifying semiology during epileptic seizures; however, we lack an automated anomaly identification system for aberrant behaviors. In this paper, we describe a novel system that is trained with known clinical manifestations from patients with mesial temporal and extra-temporal lobe epilepsy and presents aberrant semiology to physicians. METHODS: We propose a simple end-to-end-architecture based on convolutional and recurrent neural networks to extract spatiotemporal representations and to create motion capture libraries from 119 seizures of 28 patients...
December 20, 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/30616222/caregiver-impact-and-health-service-use-in-high-and-low-severity-dravet-syndrome-a-multinational-cohort-study
#9
Lieven Lagae, John Irwin, Eddie Gibson, Alysia Battersby
PURPOSE: To estimate costs associated with the current management of Dravet syndrome (DS), explore psychosocial aspects of the disease in caregivers and siblings, and identify patient characteristics associated with higher costs in a large, predominantly European survey cohort of patients and their caregivers conducted in 2016. METHODS: Health and social care resource use, productivity and quality of life (QoL) data were summarised. Costs for European five (EU5) countries (France, Germany, Italy, Spain and UK) were calculated and patients with high and low current seizure burden compared...
December 19, 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/30597400/eeg-findings-in-nmda-encephalitis-a-systematic-review
#10
REVIEW
Lisa Gillinder, Nicola Warren, Gunter Hartel, Sasha Dionisio, Cullen O'Gorman
PURPOSE: The clinical utility of EEG in cases of NMDA encephalitis is broad with many findings indicating not just epileptiform activity but also encephalopathy and potentially providing insights into pathophysiologic mechanisms of disease. We aimed to determine the frequency of different abnormalities described on EEG and their association with outcome in patients affected by NMDARE through a systematic review of all cases published. METHOD: A systematic literature review of PubMed and Embase of all published cases of anti-NMDA receptor encephalitis with EEG results, was performed from inception to January 2018...
December 19, 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/30594564/recurrent-seizure-triggered-takotsubo-a-suggestive-differential-diagnosis
#11
LETTER
Giulio Binaghi, Gildo Matta, Maurizio Melis, Daniele Pasqualucci, Maurizio Porcu
No abstract text is available yet for this article.
December 19, 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/30593875/antiepileptic-drugs-and-foetal-malformation-analysis-of-20-years-of-data-in-a-pregnancy-register
#12
F J E Vajda, J E Graham, A A Hitchcock, C M Lander, T J O'Brien, M J Eadie
PURPOSE: This paper reports additional data supplementing earlier publications based on Australian Pregnancy Register (APR) data. METHOD: Over 20 years, the APR has collected Information on pregnancies in Australian women with epilepsy (WWE), untreated WWE and those taking AEDs for other indications. Contact is by telephone, at set intervals. Treatment is not interfered with. Data are analysed using conventional statistical techniques, confidence interval methods, and logistic regression...
December 19, 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/30599396/association-between-hla-a-3201-allele-and-oxcarbazepine-induced-cutaneous-adverse-reactions-in-eastern-han-chinese-population
#13
Jianyang Xu, Xiangsong Shi, Yinghui Qiu, Yadong Zhang, Shengdi Chen, Yiwu Shi, Yulei Deng
PURPOSE: To determine genetic associations between oxcarbazepine (OXC)-induced cutaneous adverse drug reactions (cADRs) and human leukocyte antigen (HLA) variants in the Eastern Han Chinese population. METHODS: A total of 120 patients were enrolled in this study, including 30 subjects with OXC-induced cADRs (case group) and 90 OXC-tolerant patients (control group). High-resolution HLA genotyping was conducted for HLA-A, HLA-B, HLA-C, and HLA-DRB1, and allele frequencies were compared...
December 18, 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/30594807/attitudes-towards-epilepsy-in-the-uk-population-results-from-a-2018-national-survey
#14
Emily Holmes, Siobhan Bourke, Catrin Plumpton
PURPOSE: To measure stigma resulting from negative attitudes toward epilepsy in the United Kingdom (UK) population. METHODS: An online survey of a stratified quota sample of UK adults in July 2018. The primary outcome measure was the 46-item Attitudes and Beliefs about Living with Epilepsy (ABLE) scale, scored on a five-point Likert scale. Items on sociodemographic characteristics, experience of epilepsy, and knowledge of epilepsy were also included. Mean scores were calculated for the ABLE and subscales: risk and safety concerns, personal fear and social avoidance, work and role expectations, and negative stereotypes...
December 18, 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/30591281/laser-interstitial-thermotherapy-litt-in-pediatric-epilepsy-surgery
#15
REVIEW
Christian Hoppe, Christoph Helmstaedter
Laser interstitial thermotherapy (LiTT) is a novel stereotactic approach to the surgical treatment of severe drug-resistant focal epilepsies. This review extends our recent general review on this topic (Hoppe et al. Laser interstitial thermotherapy [LiTT] in epilepsy surgery. Seizure 2017; 48:45-52) with a focus on children (age <18 years). A PubMed search retrieved 25 uncontrolled case series reports that included a total of 179 pediatric patients as well as 7 review papers that specifically referred to using LiTT in pediatric epilepsy surgery (due August 31, 2018)...
December 18, 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/30590283/value-of-combined-video-eeg-and-polysomnography-in-clinical-management-of-children-with-epilepsy-and-daytime-or-nocturnal-spells
#16
Sejal V Jain, Thomas Dye, Puja Kedia
PURPOSE: Sleep disorders are common in epilepsy. Additionally, events of staring, jerking, or nocturnal behaviors are common presentations in neurology or sleep practice. Moreover, sleepiness and nocturnal awakenings are common symptoms in children with epilepsy and differentiation form ongoing seizures and sleep disorders is needed. However, limited data exist for the best evaluation methods. This study evaluated the usefulness of combined video electroencephalography (EEG) and polysomnography (PSG) studies (vEEG/PSG)...
December 17, 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/30579135/education-in-patients-with-psychogenic-nonepileptic-seizures
#17
Ali A Asadi-Pooya, Zahra Bahrami
PURPOSE: The aim of this study was to investigate any possible association between education and psychogenic nonepileptic seizures (PNES) and any potential effects education might have on clinical characteristics of patients with PNES. METHODS: In this retrospective study, all patients with PNES, who were studied at Shiraz Comprehensive Epilepsy Center at Shiraz University of Medical Sciences, from 2008 until 2018, were recruited. We categorized the patients as 1...
December 14, 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/30562653/epilepsy-field-workers-a-smartphone-application-and-telephone-telemedicine-safe-and-effective-epilepsy-care-in-rural-nepal
#18
Hemav Rajbhandari, Sweta Joshi, Shankar Malakar, Prakash Paudel, Priya Jain, Kapil Uppadaya, Mamta Singh, Victor Patterson
PURPOSE: Most people with epilepsy live in low- or middle-income countries (LMICs) where there are relatively few doctors. Over 50% of people with epilepsy in these countries are untreated so other models of care are needed. In this report we evaluate a novel model of care. METHODS: We trained four residents of Myagdi, a rural district in Nepal as epilepsy field workers (EFWs). They provided epilepsy awareness to their communities. When they identified someone with possible epilepsy they used a smartphone application (app) to determine the probability score for an episode being epileptic and contacted an epilepsy specialist by phone...
December 10, 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/30562654/seizures-as-a-clinical-manifestation-in-somatic-autoimmune-disorders
#19
REVIEW
Man Amanat, Roland D Thijs, Mona Salehi, Josemir W Sander
The risk of epileptic seizures seems increased in several systemic autoimmune disorders including systemic lupus erythematosus, type 1 diabetes mellitus, myasthenia gravis, celiac disease, rheumatoid arthritis, Hashimoto's encephalopathy, psoriasis, multiple sclerosis, neuromyelitis optica, and bullous pemphigoid. Immune dysfunction may be partly responsible for this association. Elevated levels of pro-inflammatory cytokines, autoantibodies seen in these autoimmune disorders and antibodies against neuronal antigens may contribute to the etiopathogenesis of seizures and epilepsy associated to immune conditions...
December 5, 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/30553087/ultra-short-burst-suppression-as-a-reset-switch-for-refractory-status-epilepticus
#20
Alvin S Das, Jong Woo Lee, Saef Izzy, Henrikas Vaitkevicius
No abstract text is available yet for this article.
December 5, 2018: Seizure: the Journal of the British Epilepsy Association
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