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Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne

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https://www.readbyqxmd.com/read/30648669/atrial-fibrillation-a-review-of-modifiable-risk-factors-and-preventive-strategies
#1
Alireza Sepehri Shamloo, Nikolaos Dagres, Arash Arya, Gerhard Hindricks
Atrial fibrillation (AF), as the most common cardiac arrhythmia worldwide, is associated with increased mortality and morbidity. Successful therapeutic strategies have been introduced so far, but they are associated with significant costs. Therefore, identification of modifiable risk factors of AF and the development of appropriate preventive strategies may play a substantial role in promoting community health and reducing health care system costs. Modifiable cardiovascular risk factors including obesity, hypertension, diabetes mellitus, obstructive sleep apnea, alcohol consumption, smoking, and sedentary lifestyles have been proposed as possible contributors to the development and progression of AF...
December 1, 2018: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/30521474/platelet-to-lymphocyte-ratio-predicts-all-cause-mortality-in-patients-with-carotid-arterial-disease
#2
Mujgan Tek, Mehmet Serkan Çetin, Erdem Diker, Savaş Çelebi, Basri Amasyali, Berkten Berkalp
BACKGROUND: Platelet to lymphocyte ratio (PLR) has been demonstrated as an risk and prognostic marker in many of cardiovascular diseases. Relationship between PLR and severity of carotid stenosis has been shown. The aim of our study was to investigate the relationship between PLR and all cause mortality in patients with carotid arterial disease. METODS: This retrospective study included 146 patients who had been performed selective carotid angiography. Carotid stenosis were graded by the North American Symptomatic Carotid Endarterectomy Trial (NASCET) criteria...
December 1, 2018: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/30447150/chest-pain-with-increased-troponin-level-not-always-a-cardiology-issue
#3
Stamatis S Papadatos, Stamatis J Karakatsanis, George Deligiannis, Eleni Gatsa
Thrombotic Thrombocytopenic Purpura (TTP) is a thrombotic microangiopathy syndrome resulting from decrease or absence of "a disintegrin and metalloproteinase with a thrombospondin type 1 motif member 13" (ADAMTS13). TTP has been characterized by the classical pentad of thrombocytopenia, hemolysis, fever, renal injury and neurological deficits, yet the patient may present with any atypical symptom related to microthrombi formation in the microcirculation. Here we present a rare case of a young patient with retrosternal chest pain and myocardial injury as the first manifestation of TTP...
November 15, 2018: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/30447149/metabolic-and-bone-profile-in-postmenopausal-women-with-and-without-type-2-diabetes-a-cross-sectional-study
#4
Nicoleta Dumitru, Mara Carşote, Andra Cocoloş, Eugenia Petrova, Maria Olaru, Andra Caragheorgheopol, Constantin Dumitrache, Adina Ghemigian
INTRODUCTION: Current studies support the implication of metabolic changes associated with type 2 diabetes in altering bone metabolism, structure and resistance. OBJECTIVE: We conducted a cross-sectional study on postmenopausal women aimed to analyze the differences in metabolic and bone profile in patients with and without type 2 diabetes Methods: We analyzed the metabolic and bone profile in postmenopausal women with and without type 2 diabetes(T2DM). Clinical, metabolic, hormonal parameters, along with lumbar, hip and femoral bone mineral density (BMD) and trabecular bone score (TBS) were evaluated...
November 15, 2018: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/30447148/effect-of-statins-on-hearing-function-and-subjective-tinnitus-in-hyperlipidemic-patients
#5
Hilal Yücel, Abitter Yücel, Hamdi Arbağ, Erkan Cure, Mehmet Akif Eryilmaz, Ahmet Bedri Özer
INTRODUCTION: It is known that hyperlipidemia reduces hearing functions. In this study, we aimed to study the effect of antihyperlipidemic drugs on hearing functions and tinnitus. METHODS: Eighty-four patients aged 18 to 84, who were diagnosed with hyperlipidemia and started treatment with the statin group (atorvastatin 20 mg and 40 mg, rosuvastatin 10 mg and 20 mg, and simvastatin 20 mg) of antihyperlipidemic drugs, were included in this study. All patients underwent pure-tone audiometry before starting treatment with antihyperlipidemic drugs...
November 15, 2018: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/30447147/liver-stiffness-in-chronic-hepatitis-c-virus-infection
#6
Romeo-Gabriel Mihăilă
INTRODUCTION: The severity of liver fibrosis can be assessed noninvasively today by liver stiffness measurements. Vibration-controlled transient elastography, shear wave elastography or magnetic resonance elastography are techniques increasingly used for this purpose. METHODS: This article presents the recent advances in the use of new techniques for liver fibrosis assessment in chronic hepatitis C: the correlation between liver stiffness values and liver fibrosis estimated by liver biopsies, the prognosis role of liver stiffness values, their usefulness in monitoring the treatment response, in assessing the severity of portal hypertension and in estimating the presence of esophageal varices...
November 15, 2018: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/30447146/serum-vitamin-d-level-was-not-associated-with-severity-of-ventilator-associated-pneumonia
#7
Mojtaba Hedayat Yaghoobi, Abbas Taher, Mohamad Ali Seifrabie, Mohammadmahdi Sabahi, Farshid Rahimi-Bashar
BACKGROUND AND OBJECTIVE: Vitamin D deficiency is considered one of the most common nutritional deficiencies associated with weakened immune system and increased likelihood of sepsis. The current study was conducted to investigate the association between serum vitamin D level and the severity and prognosis of ventilator associated pneumonia (VAP) in inpatients in intensive care unit (ICU). METHODS: Eighty-four consecutive patients with VAP were enrolled in this observational, prospective study conducted in the ICU of Besat Hospital, Hamadan...
November 15, 2018: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/30517081/eosinophil-count-ec-as-a-diagnostic-and-prognostic-marker-for-infection-in-the-internal-medicine-department-setting
#8
Stamatis Karakonstantis, Niki Gryllou, George Papazoglou, Charalampos Lydakis
INTRODUCTION: Eosinopenia has been previously investigated as a marker to differentiate infectious from non-infectious diagnoses and as a prognostic marker. Most previous studies were conducted in intensive care unit patients. Our study focuses on the value of eosinopenia in patients admitted to the Internal Medicine department. METHODS: We retrospectively analyzed 271 consecutive patients with infection and 31 patients presenting with fever or inflammatory syndrome and a non-infectious diagnosis...
November 1, 2018: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/30517080/ercp-practice-beyond-the-training-period-bridging-the-gap-between-guidelines-and-real-life-practice-a-single-operator-experience-of-679-procedures
#9
Theodor Voiosu, Andrei Voiosu, Andreea Benguş, Bogdan Mateescu
BACKGROUND: Endoscopic retrograde cholangiopancreatography has evolved significantly in recent years. The increase in complexity and range of applications has not been adequately reflected in an improvement of training methods for ERCP, with many endoscopists failing to meet required performance standards during their training period and limited available data on their performance immediately after completing training. We aimed to analyze the performance of an independent operator from a developing country after the completion of formal training with regard to procedure and patient-related outcomes...
November 1, 2018: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/30379642/left-ventricular-noncompaction-in-a-patient-with-systemic-lupus-erythematosus
#10
Mihaela Dobranici, Anamaria Tocitu, Caterina Delcea, Gheorghe-Andrei Dan
Left ventricular noncompaction is a rare structural cardiomyopathy that can occur isolated or in relationship with other conditions, mainly with musculoskeletal diseases or congenital heart defects. The association of left ventricular noncompaction and connective tissue disorders, including systemic lupus erythematosus, was scarcely described in the literature. Reported cases are, more likely, cardiomyopathies mimicking left ventricular noncompaction or transient left ventricular noncompaction with ventricular function improving after appropriate treatment...
October 27, 2018: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/30379641/the-relationship-of-neutrophil-to-lymphocyte-ratio-and-platelet-to-lymphocyte-ratio-in-peripheral-blood-with-st-segment-resolution-and-the-clinical-outcomes-of-stemi-patients-receiving-thrombolytic-therapy
#11
Pooneh Pashapour, Samad Ghaffarii, Ahmad Separham
INTRODUCTION: One of the inflammatory factors affecting the prognosis of myocardial infarction is the high level of neutrophil count in blood. In this study, we investigated the relationship of neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) in peripheral blood with ST-segment resolution and clinical outcomes of patients with ST-elevation myocardial infarction (STEMI) receiving thrombolytic therapy. METHODS: This cross-sectional study was conducted on the patients referring to the emergency department in Tabriz, Iran who were diagnosed with STEMI and began receiving treatment with reteplase...
October 27, 2018: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/30521478/laparoscopic-sleeve-gastrectomy-and-gastroesophageal-reflux
#12
Andrada-Loredana Popescu, Florentina Ioniţa-Radu, Mariana Jinga, Andrei-Ionuţ Gavrilă, Florin-Alexandru Săvulescu, Carmen Fierbinţeanu-Braticevici
The prevalence of obesity is rising, becoming a medical problem worldwide. Also GERD incidence is higher in obese patients compared with normal weight, with an increased risk of 2.5 of developing symptoms and erosive esophagitis. Different treatment modalities have been proposed to treat obese patients, but bariatric surgery due to its complex interactions via anatomic, physiologic and neurohormonal changes achieved the best long-term results, with sustained weight loss and decrease of complications and mortality caused by obesity...
December 1, 2018: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/30521477/pancreas-divisum-a-reemerging-risk-factor-for-pancreatic-diseases
#13
Serghei Covantev
Pancreas divisum (PD) is the most common developmental anatomic variant of pancreatic duct. The attention towards the PD has grown significantly since there are reports that this condition may cause acute relapsing pancreatitis, chronic pancreatitis and chronic abdominal pain syndrome. Furthermore, over the years, there have been multiple reports of PD associated with different types of tumors. There is evidence that PD can be associated with pancreatic tumors (up to 12.5% of cases). The golden standard for diagnosing PD is endoscopic retrograde cholangiopancreatography, but since it is an invasive procedure magnetic resonance cholangiopancreatography with secretin is a good alternative...
December 1, 2018: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/30521476/beneficial-effects-of-combined-therapy-with-lacidipine-and-candesartan-in-obese-hypertensive-patients
#14
Tatiana Ashcheulova, Nina Gerasimchuk, Olga Kovalyova, Oleksii Honchar
INTRODUCTION: Obesity is becoming one of the leading risk factors of coronary heart disease, hypertension, cerebrovascular disease. Despite the presence of a large number of antihypertensive agents and scientific substantiation of antihypertensive treatment principles it would be wrong to assume that the problem is completely solved. Development of endothelial dysfunction is one of the key pathogenic mechanisms in hypertension. This process is proven to have contributed by immune inflammation activation which is mediated by pro-inflammatory cytokines and oxidative stress...
December 1, 2018: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/30521475/multiple-acute-ischemic-strokes-as-the-onset-manifestation-of-acute-promyelocytic-leukemia
#15
Maria Mirabela Manea, Ana Maria Dobri, Dorin Dragoş, Gabriela Borsaru, Sorin Tuţă
Acute promyelocytic leukemia often manifests with hemorrhagic diathesis, thrombotic events being much rarer. This is the case of a 59-year-old patient with thrombotic cerebro-vascular complications as the onset manifestation of acute promyelocytic leukemia.
December 1, 2018: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/30375357/effect-of-reducing-medication-regimen-complexity-on-glycaemic-control-in-patients-with-diabetes
#16
Tarek Samy Abdelaziz, Khaled Marzouk Sadek
INTRODUCTION: Medication Regimen complexity is an important issue of patients care that needs to be addressed. The aim of this study is the safe reduction of regimens complexities. The effect of this intervention on glycemic control was assessed in this study. METHODS: Seventy eight patients were recruited to the study. The entry criteria were non optimal glycemic, non-adherence (as demonstrated by indirect tools), and polypharmacy. The only intervention was the safe reduction of medication regimen complexity...
October 4, 2018: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/30375354/is-recurrent-kikuchi-fujimoto-disease-a-precursor-to-systemic-lupus-erythematosus
#17
Taro Horino, Osamu Ichii, Yoshio Terada
Kikuchi-Fujimoto disease (KFD), also known as histiocytic necrotizing lymphadenitis, is a rare, benign, self-limiting disease characterized by cervical lymphadenopathy and fever. Since KFD was first reported in 1972, the validity of this clinical entity has been controversial and its aetiology remains unknown. Herein, we report a case of a patient with KFD, which was believed to be associated with systemic lupus erythematosus.
October 4, 2018: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/30375351/cardiac-sarcoidosis-case-presentation-and-review-of-the-literature
#18
Natalia Chamorro-Pareja, Julian A Marin-Acevedo, Razvan M Chirila
Cardiac sarcoidosis usually occurs in the context of systemic disease; however, isolated cardiac involvement can occur in up to 25% of cases and tends to be clinically silent. When symptoms are present, they are often nonspecific and occasionally fatal, representing a diagnostic challenge. A high index of clinical suspicion and the integration of appropriate imaging, laboratory, and pathologic findings is always required. Treatment aims to control the systemic inflammatory condition while preventing further cardiac damage...
October 1, 2018: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/30375352/profiles-of-peptide-yy-and-ghrelin-levels-of-hunger-and-satiety-and-ad-libitum-intake-in-obese-and-non-obese-indonesian-women
#19
Fiastuti Witjaksono, Marcellus Simadibrata, Lukito Wijaya, Andi Wijaya, Fariz Nurwidya
INTRODUCTION: The current study aimed to assess profiles of peptide YY and ghrelin, visual analog scales (VAS) for hunger and satiety, and ad libitum intake in obese and non-obese women. METHODS: This open-label non-randomized interventional study involved obese (BMI ≥ 25 - 35 kg/m2) and non-obese (BMI 18.5 - 23.0 kg/m2) women subjects. Levels of peptide YY and ghrelin were determined by radioimmunoassay and enzyme-linked immunosorbent assay (ELISA), respectively, while the degrees of hunger and satiety were measured using visual analog scale (VAS) questionnaires...
September 25, 2018: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/30375353/profile-of-hepatocellular-carcinoma-in-the-republic-of-moldova-first-hand-information-on-the-presentation-distribution-and-etiologies
#20
Adela Turcanu, Ecaterina Pitel, Vlada-Tatiana Dumbrava, Eugen Tcaciuc, Ana Donscaia, Angela Peltec, Pascal Pineau
INTRODUCTION: Moldova is the European country with the highest incidence of hepatocellular carcinoma (HCC) in both sexes. There is, however, no data comprehensively describing the presentation and the risk factors of HCC in the country. We decided to analyze cases of HCC recently received in a tertiary healthcare Institution from Chisinau, the Moldovan capital. METHODS: A series of 148 primary liver tumors including 139 cases of HCC were retrospectively analyzed for demographic features, serological and biochemical data, and clinical presentation...
September 19, 2018: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
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