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Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne

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https://www.readbyqxmd.com/read/29791319/malignancy-in-a-retrospective-cohort-of-17-patients-with-dermatomyositis-or-polymyositis-in-southern-tunisia
#1
Khadija Sellami, Madiha Mseddi, Mouna Snoussi, Hela Gharbi, Faten Frikha, Rayda Ben Salah, Moez Jallouli, Sameh Marzouk, Abderrahmen Masmoudi, Zouhir Bahloul, Hamida Turki
INTRODUCTION: The prognosis of dermatomyositis (DM)/polymyositis (PM) in adults is partly related to their association with neoplasia. The aim of our study was to report the epidemiologic, clinical, paraclinical, therapeutic and evolutionary aspects of DM associated with malignancy in patients from Sfax, south eastern of Tunisia. METHODS: A retrospective cohort study of patients with DM or PM admitted in Dermatology and Internal Medicine Departments of Hedi Chaker University Hospital of Sfax between 1996 and 2015...
May 21, 2018: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/29742066/endoscopic-management-of-recurrent-tracheoesophageal-fistula-induced-by-chronic-use-of-nonsteroidal-anti-inflammatory-drugs-a-case-report-and-review-of-the-literature
#2
Theodor Alexandru Voiosu, Andrada Viorela Gheorghe, Dan Adrian Bobeica, Andrei Mihai Voiosu, Radu Bogdan Mateescu
Tracheoesophageal fistula (TEF) is frequently congenital and requires surgical correction. TEF can also occur secondary to malignant esophageal tumors or benign diseases and these cases are managed by endoscopic means, such as closing the defect with metallic stents. Although esophageal injury can occur secondary to nonsteroidal anti-inflammatory drugs (NSAIDs), TEF secondary to chronic NSAIDs use hasn't been described in the literature. We report the case of a male patient with refractory migraine and chronic use of NSAIDs, with a history of esophageal stenosis presenting with acute-onset total dysphagia...
May 8, 2018: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/29791318/the-inhibitors-a-challenge-for-the-management-of-patients-with-hereditary-haemophilia-a
#3
Romeo-Gabriel Mihăilă
INTRODUCTION: Our research strategy was aimed at evaluating the possible implication of the type of factor VIII product administered as substitution treatment to haemophilia A patients in the occurrence of inhibitors and their consequences on the management. METHODS: Scientific articles from July 2015 to July 2017 were searched using the PubMed and PubMed Central databases. The used search terms included "haemophilia A", "inhibitors", "plasma-derived factor VIII" and "recombinant factor VIII"...
May 1, 2018: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/29791317/romanian-registry-of-hypertrophic-cardiomyopathy-overview-of-general-characteristics-and-therapeutic-choices-at-a-national-level
#4
Paula Ionilă, Ruxandra Jurcuţ, Nicoleta Ferariu, Monica Roşca, Monica Chivulescu, Adriana Mursă, Sebastian Militaru, Alin A Ionescu, Cristina Căldăraru, Ana G Fruntelată, Silvia F Goanţă, Simina Crișan, Adina Ionac, Ana-Maria Avram, Attila Frigy, Radu Sascãu, Cãtãlina Arsenescu-Georgescu, Ioan M Coman, Bogdan A Popescu, Carmen Ginghină, Eduard Apetrei
Hypertrophic cardiomyopathy (HCM) is a disease with increased LV wall thickness not solely explained by abnormal loading conditions, with great heterogeneity regarding clinical expression and prognosis. The aim of the present study was to collect data on HCM patients from different centres across the country, in order to assess the general characteristics and therapeutic choices in this population.
May 1, 2018: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/29561733/cardiovascular-risk-factors-in-a-roma-sample-population-from-romania
#5
Emma Weiss, Cristina Japie, Ana Maria Balahura, Daniela Bartos, Elisabeta Badila
BACKGROUND: The Roma population has a high prevalence of cardiovascular risk factors, higher mortality, and shorter life expectancy. It is found in largest numbers in Romania, but published data are still scarce here. We studied cardiovascular risk factors and disease along with target organ damage on a population of Roma inhabitants from Bucharest, Romania. METHODS: This cross-sectional study enrolled, in a community-based participatory research manner, 806 Roma subjects (18-83 years)...
March 19, 2018: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/29561732/the-severity-of-coronary-artery-disease-was-not-associated-with-non-alcoholic-fatty-liver-disease-in-a-series-of-264-non-diabetic-patients-who-underwent-coronary-angiography
#6
Taraneh Faghihi Langroudi, Habib Haybar, Saeed Alipour Parsa, Mohamad Mahjoorian, Isa Khaheshi, Mohammadreza Naderian
BACKGROUND: It is now suggested an association between non-alcoholic fatty liver disease (NAFLD) and the occurrence of coronary artery disease even in non-diabetic patients. We will determine the rate of NAFLD and its main determinants in non-diabetic patients undergoing coronary angiography. METHODS: This cross-sectional study was accomplished on 264 patients who were candidates for coronary angiography during the year 2016. Coronary angiography has been done to depict the presence or absence of coronary involvement, and the severity of coronary artery disease by determining the number of vessels involved and also the SYNTAX score...
March 19, 2018: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/29533904/downregulation-of-tumor-suppressor-gene-lhx6-in-cancer-a-systematic-review
#7
Evelyn Nathalia, Madelaine Skolastika Theardy, Sharleen Elvira, Graciella Rosellinny, Andrew Steven Liyanto, Michael Putra Utama, Anton Sumarpo
INTRODUCTION: LIM Homeobox 6 (LHX6) encodes a LIM homeodomain transcription factor, contributes to tissue development and morphogenesis, and is mostly expressed in medial ganglionic eminence and odontogenic mesenchyme. However, it has been reported to play a role in cancer progression. This narrative review summarizes literatures that emphasize the molecular regulation of LHX6 in tumorigenesis. METHODS: In our systematic review, the PubMed database was used for the literature search using the combination of words that included "LHX6" and "cancer"...
March 9, 2018: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/29453929/the-diagnostic-and-prognostic-value-of-serum-endocan-in-patients-with-cirrhotic-cardiomyopathy
#8
Andrei Mihai Voiosu, Paul Bălănescu, Ioana Daha, Bianca Smarandache, Aurelia Rădoi, Radu Bogdan Mateescu, Cristian Răsvan Băicuş, Theodor Alexandru Voiosu
BACKGROUND: We aimed to determine the relationship between endocan and cirrhotic cardiomyopathy. MATERIALS AND METHODS: Patients with liver cirrhosis and no heart disease were included in a prospective observational study with liver disease decompensation and death as primary outcomes. RESULTS: 83 cirrhotic patients were included and 32 had cirrhotic cardiomyopathy. Endocan levels were significantly lower in patients with cirrhotic cardiomyopathy (5...
March 9, 2018: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/29590083/efficacy-of-gefitinib-and-radiotherapy-combination-in-indonesian-patients-with-lung-adenocarcinoma
#9
Elisna Syahruddin, Aida Lufti Huswatun, Ari Prabowo, Jamal Zaini, Fariz Nurwidya, Achmad Hudoyo, Anwar Jusuf
INTRODUCTION: Combinations of gefitinib and radiotherapy have been observed to have synergistic and anti-proliferative effects on lung cancer in vitro. In the clinical setting, patients who presented with respiratory difficulties such as superior vena cava syndrome (SVCS), radiotherapy should be given immediately to address the emergency while waiting for the results of epidermal growth factor receptor (EGFR) mutation test. However, there has been no study that described the role of radiotherapy in Indonesian patients with EGFR-mutant lung adenocarcinoma...
March 1, 2018: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/29080394/trainee-involvement-increases-precut-rates-and-delays-access-to-the-common-bile-duct-without-an-increase-in-procedure-related-adverse-events-a-brave-new-world-of-ercp-training
#10
Theodor Voiosu, Andrei Voiosu, Andreea Benguş, Mihai Rimbaş, Bogdan Mateescu
BACKGROUND AND AIMS: Selective cannulation of the desired duct is a key element in ERCP procedures and an important step in the training of fellows. However, there is limited data about technical success and patient safety for ERCPs conducted in a training setting.We aimed to evaluate the impact of trainee involvement on the cannulation technique and procedure related outcomes at ERCP. MATERIALS AND METHODS: We conducted an observational study of all ERCP conducted in an endoscopy unit with an on-going training program...
March 1, 2018: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/29080393/lipid-profile-pattern-in-pediatric-overweight-population-with-or-without-nafld-in-relation-to-idf-criteria-for-metabolic-syndrome-a-preliminary-study
#11
Anca Bălănescu, Paul Bălănescu, Valentina Comănici, Iustina Stan, Beata Acs, Laura Prisăcariu, Florin Brezan, Tatiana Ciomârtan, Ioan Gherghina
BACKGROUND AND AIMS: The aim of this study is to assess the lipid profile pattern of pediatric overweight and/or obese patients with Non-Alcoholic Fatty Liver Disease (NAFLD) in relation to IDF Consensus Criteria for Metabolic Syndrome (MetS). MATERIAL AND METHODS: We conducted a cross-sectional preliminary study on 45 consecutive pediatric patients. Overweight or obese children aged from 3 to 18 years were included. Standardized measurement of blood pressure and anthropometric parameters were performed...
March 1, 2018: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/29028632/procalcitonin-as-a-diagnostic-and-prognostic-marker-in-diabetic-foot-infection-a-current-literature-review
#12
REVIEW
Dimitrios Velissaris, Nikolaos-Dimitrios Pantzaris, Christina Platanaki, Nikolina Antonopoulou, Charalampos Gogos
Diabetic foot ulcers (DFUs) are a very common cause of mortality and morbidity. The distinction between infected and non-infected DFU remains a very challenging task for clinicians in everyday practice. Even when infection is documented, the spectrum of diabetic foot infection is wide, ranging from cellulitis and soft tissue infection to osteomyelitis. Procalcitonin (PCT), a well-established sepsis biomarker, has been used in the diagnosis of several infections including osteomyelitis in patients with diabetes mellitus...
March 1, 2018: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/28991776/serum-and-alveolar-procalcitonin-had-a-weak-diagnostic-value-for-ventilator-associated-pneumonia-in-patients-with-pulmonary-infection-score-%C3%A2-6
#13
Mehran Shokri, Roya Ghasemian, Masomeh Bayani, Parviz Amri Maleh, Masoumeh Kamrani, Mahmoud Sadeghi-Haddad-Zavareh, Soheil Ebrahimpour
BACKGROUND: Measuring the serum and alveolar procalcitonin level as inflammatory marker in the diagnosis of ventilator-associated pneumonia (VAP) has been taken into account. In this study, serum and alveolar procalcitonin levels in patients with suspected VAP and patients with confirmed VAP were compared. METHODS: This cross-sectional study was conducted using 50 intubated intensive care unit (ICU) patients, connected to ventilator, from October 2014 to April 2015...
March 1, 2018: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/28976911/association-of-cognitive-emotional-regulation-strategies-to-depressive-symptoms-in-type-2-diabetes-patients
#14
Andreia Ş Mocan, Silvia Ş Iancu, Adriana S Băban
AIM: The present cross-sectional observational study aimed to investigate the relation between cognitive-emotional regulation strategies and depressive symptoms in type 2 diabetes patients in the context of sociodemographic and clinical factors, of diabetes distress, perception of illness consequences and previous depression. METHOD: Multiple logistic regression was performed on the responses of 354 adults with type 2 diabetes (58.5% women; mean ± SD age: 61.14 ± 8...
March 1, 2018: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/28945608/association-of-neutrophil-to-lymphocyte-ratio-and-microalbuminuria-in-patients-with-normal-egfr
#15
Aysun Aybal Kutlugun, Fatma Ayerden Ebinc, Mujgan Tek Ozturk, Fatma Kaplan Efe, İbrahim Karadag, Murat Eser, Oktay Unsal, Serdar Karakaya
AIMS: The aim of this study was to evaluate the association between neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and microalbuminuria in patients with normal estimated glomerular filtration rate (eGFR). METHODS: 174 patients who had eGFR ≥ 60 mL/min/1.73 m2 were studied. Patients were divided into two groups according to the urinary albumin excretion as microalbuminuric group (n = 105) and normoalbuminuric group (n = 69). NLR and PLR levels were calculated...
March 1, 2018: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/28918421/macrophage-activation-syndrome-at-the-onset-of-glucocorticoid-resistant-systemic-lupus-erythematosus-a-case-report
#16
Delia Tulbă, Marius Balea, Cristian Băicuş
INTRODUCTION: Macrophage activation syndrome (MAS) is a life-threatening hyperinflammatory state mediated by uncontrolled cytokine storm and haemophagocytosis. Although rarely reported, MAS might occur in systemic lupus erythematosus (SLE), notably as an inaugural manifestation. Glucocorticoids (GCs) are the cornerstone of SLE therapy. However, in some cases high doses of GCs are required to achieve remission (i.e. glucocorticoid-resistance), leading to significant side effects. CASE REPORT: A 28-year-old Romani male was admitted to our hospital for polyarthralgia, polyserositis and fatigability...
March 1, 2018: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/28865234/impact-of-seminal-plasma-trace-elements-on-human-sperm-motility-parameters
#17
Mohammad Mostakhdem Hashemi, Nasser Behnampour, Mojgan Nejabat, Afsaneh Tabandeh, Behrouz Ghazi-Moghaddam, Hamid Reza Joshaghani
INTRODUCTION: Human seminal plasma contains a variety of macro and trace elements including magnesium (Mg), copper (Cu), zinc (Zn), and iron (Fe) that have essential roles in normal functioning of semen and its quality. The imbalance of these elements has been reported in several pathologic and male infertility disorders. Therefore, this study aimed to determine the levels of these elements in seminal plasma samples, their relationships with each other and their impact on sperm motility...
March 1, 2018: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/28865233/first-allergenic-pollen-monitoring-in-bucharest-and-results-of-three-years-collaboration-with-european-aerobiology-specialists
#18
Polliana Mihaela Leru, Ana-Maria Eftimie, Michel Thibaudon
INTRODUCTION: Respiratory allergies induced by allergenic plants pollen represent an important public health problem with increasing prevalence and severity. Aerobiologic study of allergenic pollens is performed in many countries on regular basis and correlated with health data from allergists in the frame of national aerobiology networks. Romania has no aerobiology network and pollen measurements have been done between 1999-2012 in West region only. In the frame of COST Action called Sustainable management of Ambrosia artemisiifolia in Europe (SMARTER FA 1203), three years collaboration with Reseau National de Surveillance Aerobiologique (RNSA) from France and the first pollen monitoring center in Bucharest were established...
March 1, 2018: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/28865232/hyponatremia-bone-mineral-density-and-falls-in-the-elderly-results-from-ahap-study
#19
Seyed Reza Hosseini, Naghi Baghitabar, Ali Mirzapour, Farshid Oliaei, Hajighorban Nooreddini, Ali Bijani, Simin Mouodi
BACKGROUND: Hyponatremia (HN) can be associated with osteoporosis, falls and bone fractures in the elderly. Recent researches demonstrated different results about the correlation of HN with bone mineral density and bone fractures. METHODS: This analytic research came from the AHAP project in northern IRAN. All people aged 60 years and over were included in the study. Individuals with severe comorbidities and then who had concurrent conditions which could have impact on bone mineral densities (BMD) such as long-term use of steroids, calcium and/or vitamin D supplements, bisphosphonates, calcitonin, thiazides and hormonal medications were excluded...
March 1, 2018: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/28792914/reply-pulmonary-thromboembolism-in-an-emergency-hospital-are-our-patients-different
#20
LETTER
Petros Ioannou
No abstract text is available yet for this article.
March 1, 2018: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
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