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https://www.readbyqxmd.com/read/28087986/barriers-to-access-to-opioid-medicines-for-patients-with-opioid-dependence-a-review-of-legislation-and-regulations-in-eleven-central-and-eastern-european-countries
#1
Marjolein J M Vranken, Aukje K Mantel-Teeuwisse, Saskia Jünger, Lukas Radbruch, Willem Scholten, John A Lisman, Marija Subataite, Marie-Hélène D B Schutjens
BACKGROUND AND AIMS: Barriers linked to drug control systems are considered to contribute to inequitable access to controlled medicines, leaving millions of people in pain and suffering. Most studies focus on access to opioids for the treatment of severe (cancer) pain. This study aims to identify specific access barriers for patients with opioid dependence in legislation and regulations of 11 Central and Eastern European countries. METHODS: This study builds on a previous analysis of legislation and regulations as part of the EU 7th Framework Access To Opioid Medication in Europe (ATOME) project...
January 14, 2017: Addiction
https://www.readbyqxmd.com/read/28061017/feasibility-and-safety-of-extended-release-naltrexone-treatment-of-opioid-and-alcohol-use-disorder-in-hiv-clinics-a-pilot-feasibility-randomized-trial
#2
P Todd Korthuis, Paula J Lum, Pamela Vergara-Rodriguez, Keith Ahamad, Evan Wood, Lynn E Kunkel, Neal L Oden, Robert Lindblad, James L Sorensen, Virgilio Arenas, Doan Ha, Raul N Mandler, Dennis Mccarty
BACKGROUND AND AIMS: HIV-infected persons with substance use disorders are least likely to benefit from advances in HIV treatment. Integration of extended-release naltrexone (XR-NTX) into HIV clinics may increase engagement in the HIV care continuum by decreasing substance use. We aimed to compare 1) XR-NTX treatment initiation, 2) retention, and 3) safety of XR-NTX versus treatment as usual (TAU) for treating opioid use disorder (OUD) and/or alcohol use disorder (AUD) in HIV clinics...
January 6, 2017: Addiction
https://www.readbyqxmd.com/read/28060454/trait-and-neurobiological-underpinnings-of-negative-emotion-regulation-in-gambling-disorder
#3
Juan F Navas, Oren Contreras-Rodríguez, Juan Verdejo-Román, Ana Perandrés-Gómez, Natalia Albein-Urios, Antonio Verdejo-García, José C Perales
BACKGROUND AND AIMS: Gambling disorder is characterized by poor regulation of negative emotions and impulsive behaviors. This study aimed to (1) compare gambling disorder patients (GDPs) and healthy controls (HCs) in self-report and brain activation measures of emotion regulation; and (2) establish its relationship with negative emotion-driven impulsivity. DESIGN: Two cross-sectional case-control studies including GDPs and HCs. SETTING AND PARTICIPANTS: GDPs and HCs were recruited from specialized gambling clinics in Andalusia (Spain), where they were following outpatient treatment, and from the community, respectively...
January 6, 2017: Addiction
https://www.readbyqxmd.com/read/28060453/model-based-economic-evaluations-in-smoking-cessation-and-their-transferability-to-new-contexts-a-systematic-review
#4
REVIEW
Marrit L Berg, Kei Long Cheung, Mickaël Hiligsmann, Silvia Evers, Reina J A de Kinderen, Puttarin Kulchaitanaroaj, Subhash Pokhrel
AIMS: To identify different types of models used in economic evaluations of smoking cessation, analyse the quality of the included models examining their attributes and ascertain their transferability to a new context. METHODS: A systematic review of the literature on the economic evaluation of smoking cessation interventions published between 1996 and April 2015, identified via Medline, EMBASE, NHS EED, and HTA. Checklist-based quality of the included studies and transferability scores were based on European Network of Health Economic Evaluation Databases (EURONHEED) criteria...
January 6, 2017: Addiction
https://www.readbyqxmd.com/read/28060450/effects-of-increased-alcohol-availability-during-adolescence-on-the-risk-of-all-cause-and-cause-specific-disability-pension-a-natural-experiment
#5
Emelie Thern, Jeroen de Munter, Tomas Hemmingsson, George Davey Smith, Mats Ramstedt, Per Tynelius, Finn Rasmussen
AIM: To test if being exposed to increased alcohol availability during adolescence is associated with an increased risk of receiving disability pension due to all-cause, alcohol use disorders and mental disorders. DESIGN: Register-based population-based study using a natural experiment setting, the alcohol policy change in Sweden (1967-1968), with increased access to strong beer in a narrow time window and geographical area. The individuals exposed to the policy change were compared with non-exposed individuals living in the rest of Sweden, excluding a border area...
January 6, 2017: Addiction
https://www.readbyqxmd.com/read/28060437/trajectories-of-heroin-use-10-11-year-findings-from-the-australian-treatment-outcome-study
#6
Maree Teesson, Christina Marel, Shane Darke, Joanne Ross, Tim Slade, Lucy Burns, Michael Lynskey, Sonja Memedovic, Joanne White, Katherine L Mills
AIMS: To identify trajectories of heroin use in Australia, predictors of trajectory group membership, and subsequent outcomes, among people with heroin dependence over 10-11-years. DESIGN: Longitudinal cohort study. SETTING: Sydney, Australia. PARTICIPANTS: 615 participants were recruited between 2001-2002 as part of the Australian Treatment Outcome Study (66.2% male; mean age 29). The predominance of the cohort (87...
January 6, 2017: Addiction
https://www.readbyqxmd.com/read/28058758/passengers-at-risk-a-multi-level-analysis-of-the-decision-to-travel-with-a-drunk-driver
#7
José Ignacio Nazif, Rony Blank-Gomel
AIMS: To assess the impact of demographic, intrapersonal and environmental factors on the likelihood in Chile of becoming a passenger of an alcohol-impaired driver (PAID). DESIGN: Multi-level cross-sectional study. SETTING: Data were acquired from two large-scale household surveys of representative samples of Chile's Metropolitan Region. PARTICIPANTS: The study included 1341 individuals ≥ 16 years. 696 of them reported engaging in PAID...
January 6, 2017: Addiction
https://www.readbyqxmd.com/read/28054421/tens-of-millions-successfully-in-long-term-recovery-let-us-find-out-how-they-did-it
#8
John F Kelly
No abstract text is available yet for this article.
January 4, 2017: Addiction
https://www.readbyqxmd.com/read/28044376/psychosocial-interventions-in-opiate-substitution-treatment-services-does-the-evidence-provide-a-case-for-optimism-or-nihilism
#9
Ed Day, Luke Mitcheson
BACKGROUND AND AIMS: Clinical guidelines from around the world recommend the delivery of psychosocial interventions as part of routine care in opiate substitution treatment (OST) programmes. However, although individual studies demonstrate benefit for structured psychosocial interventions, meta-analytical reviews find no benefit for manual-based treatments beyond 'routine counselling'. ANALYSIS: We consider the question of whether OST medication alone is sufficient to produce the required outcomes, or whether greater efforts should be made to provide high-quality psychosocial treatment alongside medication...
January 2, 2017: Addiction
https://www.readbyqxmd.com/read/28029718/a-smart-data-analysis-method-for-constructing-adaptive-treatment-strategies-for-substance-use-disorders
#10
Inbal Nahum-Shani, Ashkan Ertefaie, Xi Lu, Kevin G Lynch, James R McKay, David Oslin, Daniel Almirall
AIMS: To demonstrate how Q-learning, a novel data analysis method, can be used with data from a sequential, multiple assignment, randomized trial (SMART) to construct empirically an adaptive treatment strategy (ATS) that is more tailored than the ATSs already embedded in a SMART. METHOD: We use Q-learning with data from the Extending Treatment Effectiveness of Naltrexone (ExTENd) SMART (N = 250) to construct empirically an ATS employing naltrexone, behavioral intervention, and telephone disease management to reduce alcohol consumption over 24 weeks in alcohol dependent individuals...
December 28, 2016: Addiction
https://www.readbyqxmd.com/read/28029198/neural-responses-to-negative-outcomes-predict-success-in-community-based-substance-use-treatment
#11
Sarah E Forster, Peter R Finn, Joshua W Brown
BACKGROUND AND AIMS: Activation in some specific brain regions has demonstrated promise as prognostic indicators in substance dependent individuals (SDIs) but this issue has not yet been explored in SDIs attending typical of community-based treatment. We used a data-driven, exploratory approach to identify brain-based predictors of treatment outcome in a representative community sample of SDIs. The predictive utility of brain-based measures was evaluated against clinical indicators, cognitive-behavioral performance, and self-report assessments...
December 28, 2016: Addiction
https://www.readbyqxmd.com/read/28010052/adolescents-at-risk-for-drug-abuse-a-3-year-dual-process-analysis
#12
S L Ames, B Xie, Y Shono, A W Stacy
AIMS: To test longitudinal additive and synergistic dual process models in youth at documented risk for drug use. The specific dual process approach examined suggests that engaging in drug use behaviors results from a dynamic interplay between automatically-activated associative memory processes and executive reflective/control processes. DESIGN: This 3-year, three-wave population-based prospective study used mobile computer-based assessments. SETTING: Self-directed computer assessments were completed in school settings in the Los Angeles metropolitan area, California, USA...
December 23, 2016: Addiction
https://www.readbyqxmd.com/read/28009931/do-more-robust-prescription-drug-monitoring-programs-reduce-prescription-opioid-overdose
#13
Bryce Pardo
BACKGROUND AND AIMS: In the United States, overdose deaths attributed to opioid pain relievers (OPR) have quadrupled since 1999, prompting many states to adopt Prescription Drug Monitoring Programs (PMP). This study aimed to 1) estimate the relationship of PMP strength with OPR overdose deaths across states and over time; 2) measure what threshold in PMP strength is associated with the greatest reduction in OPR overdose; and 3) assess the relationship of medical marijuana dispensaries with OPR overdose deaths...
December 23, 2016: Addiction
https://www.readbyqxmd.com/read/27995679/some-pwid-communities-are-ready-for-prep-so-what-s-next
#14
Julie Bruneau, Élise Roy, Nicolas Demers, Joseph Cox
No abstract text is available yet for this article.
December 20, 2016: Addiction
https://www.readbyqxmd.com/read/27981669/alcohol-use-disorder-and-divorce-evidence-for-a-genetic-correlation-in-a-population-based-swedish-sample
#15
Jessica E Salvatore, Sara Larsson Lönn, Jan Sundquist, Paul Lichtenstein, Kristina Sundquist, Kenneth S Kendler
AIMS: We tested the association between alcohol use disorder (AUD) and divorce; estimated the genetic and environmental influences on divorce; estimated how much genetic and environmental influences accounted for covariance between AUD and divorce; and estimated latent genetic and environmental correlations between AUD and divorce. We tested sex differences in these effects. DESIGN: We identified twin and sibling pairs with AUD and divorce information in Swedish national registers...
December 16, 2016: Addiction
https://www.readbyqxmd.com/read/27981724/why-the-mechanisms-of-12-step-behaviour-change-should-matter-to-clinicians
#16
David Best
No abstract text is available yet for this article.
December 15, 2016: Addiction
https://www.readbyqxmd.com/read/27981691/the-costs-of-crime-during-and-after-publicly-funded-treatment-for-opioid-use-disorders-a-population-level-study-for-the-state-of-california
#17
Emanuel Krebs, Darren Urada, Elizabeth Evans, David Huang, Yih-Ing Hser, Bohdan Nosyk
BACKGROUND AND AIMS: Treatment for opioid use disorders (OUD) reduces the risk of mortality and infectious disease transmission; however, opportunities to quantify the potential economic benefits of associated decreases in drug-related crime are scarce. This paper aimed to estimate the costs of crime during and after periods of engagement in publicly-funded treatment for OUD to compare total costs of crime over a hypothetical 6-month period following initiation of opioid agonist treatment (OAT) versus detoxification...
December 15, 2016: Addiction
https://www.readbyqxmd.com/read/27981670/understanding-the-alcohol-harm-paradox-an-analysis-of-sex-and-condition-specific-hospital-admissions-by-socioeconomic-group-for-alcohol-associated-conditions-in-england
#18
Susannah Sadler, Colin Angus, Lucy Gavens, Duncan Gillespie, John Holmes, Jean Hamilton, Alan Brennan, Petra Meier
BACKGROUND AND AIMS: In many countries conflicting gradients in alcohol consumption and alcohol-associated mortality have been observed. To understand this 'alcohol harm paradox' we analysed the socioeconomic gradient in alcohol-associated hospital admissions to test whether it was greater in conditions which were : (1) chronic (associated with long-term drinking) and partially alcohol-attributable, (2) chronic and wholly alcohol-attributable, (3) acute (associated with intoxication) and partially alcohol-attributable, (4) acute and wholly-alcohol attributable...
December 15, 2016: Addiction
https://www.readbyqxmd.com/read/27943493/adolescent-drinking-a-touch-of-social-class
#19
Hilde Pape, Thor Norström, Ingeborg Rossow
AIMS: To estimate whether parental socioeconomic status (SES) is associated with adolescent drinking, and the degree to which a possible association may be accounted for by various parental factors. DESIGN AND SETTING: Cross-sectional Norwegian school survey from 2006 (response rate: 86%). PARTICIPANTS: Students aged 13-14 years (n = 5797), 15-16 years (n = 6613) and 17-18 years (n = 5351), of whom 51% were girls. MEASUREMENTS: Parents' education was our main SES indicator, and we distinguished between low (7%) and middle/high (93%) educational level...
December 11, 2016: Addiction
https://www.readbyqxmd.com/read/27936293/effects-of-incentives-for-naltrexone-adherence-on-opiate-abstinence-in-heroin-dependent-adults
#20
Brantley P Jarvis, August F Holtyn, Anthony DeFulio, Kelly E Dunn, Jeffrey J Everly, Jeannie-Marie S Leoutsakos, Annie Umbricht, Michael Fingerhood, George E Bigelow, Kenneth Silverman
AIM: To test whether an incentive-based intervention that increased adherence to naltrexone also increased opiate abstinence. DESIGN: Post-hoc combined analysis of three earlier randomized controlled trials that individually showed that incentives for adherence to oral and to extended-release injection naltrexone dosing schedules increased naltrexone adherence but not opiate abstinence. SETTING: Outpatient therapeutic workplace in Baltimore, MD, USA...
December 9, 2016: Addiction
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