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European Journal of Cancer Care

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https://www.readbyqxmd.com/read/28809461/cancer-comorbidity-and-workplace-discrimination-the-us-experience
#1
Amanda K Gehrke, Michael Feuerstein
Cancer survivors with comorbidities have more work-related challenges than cancer survivors without these other health problems. This study evaluated how these cancer survivors with comorbidities are faring under a newly revised workplace discrimination policy, which better accounts for the episodic nature of chronic illnesses. The sample included 18-64 year olds with a history of cancer who filed allegations of workplace discrimination in 2009-2011 (N = 1.291) in the US. Multivariable logistic regressions were used...
August 15, 2017: European Journal of Cancer Care
https://www.readbyqxmd.com/read/28809459/intensity-of-integrated-cancer-palliative-care-plans-and-end-of-life-acute-medical-hospitalisation-among-cancer-patient%C3%A2-in-northern-italy
#2
Michele Pellizzari, Maria Rolfini, Eliana Ferroni, Valentina Savioli, Nicola Gennaro, Elena Schievano, Francesco Avossa, Elisabetta Pinato, Maria Cristina Ghiotto, Franco Figoli, Domenico Mantoan, Antonio Brambilla, Ugo Fedeli, Mario Saugo
A high hospital utilisation at the end of life (EOL) is an indicator of suboptimal quality of health care. We evaluated the impact of the intensity of different Integrated Cancer Palliative Care (ICPC) plans on EOL acute medical hospitalisation among cancer decedents. Decedents of cancer aged 18-84 years, who were residents in two Italian regions, were investigated through integrated administrative data. Outcomes considered were prolonged hospital stay for medical reasons, 2+ hospitalisations during the last month of life and hospital death...
August 15, 2017: European Journal of Cancer Care
https://www.readbyqxmd.com/read/28809066/participation-in-water-exercising-long-term-after-breast-cancer-surgery-experiences-of-significant-factors-for-continuing-exercising-as-a-part-of-cancer-rehabilitation
#3
A Enblom, H Lindquist, K Bergmark
Although physical exercising has great benefits, little is known regarding factors of significance for cancer survivors to continue exercising within their rehabilitation. The objective was to describe factors experienced to be of significance for cancer survivors to continue with water-exercising long-term after breast cancer surgery. Women (n = 29) who had undergone breast cancer surgery (mastectomy 79%, axillary surgery 86%, and radiotherapy 86%) for median (md) 13 (25th-75th percentile 3-21.5) was followed up regarding their rehabilitation, arm function Disabilities of Arm Shoulder and Hand (md 14, IQR 7-32), EQ-5D score (md 0...
August 15, 2017: European Journal of Cancer Care
https://www.readbyqxmd.com/read/28795458/a-comprehensive-review-of-sexual-health-concerns-after-cancer-treatment-and-the-biopsychosocial-treatment-options-available-to-female-patients
#4
REVIEW
Carly S Sears, John W Robinson, Lauren M Walker
The repercussions of cancer diagnosis and treatment profoundly impact the sexual wellbeing of women prior to, during, and following cancer treatment. Sexual health concerns are often under-addressed within clinical and research settings, and information tends to be limited to women with breast or gynecological cancers. In this narrative literature review, the authors critically evaluate research published between 1990 and 2016, pertaining to sexual health concerns of women diagnosed with cancer, of any type or stage, and to the psychosocial and biomedical interventions that currently exist for the treatment of sexual health-related side-effects (e...
August 10, 2017: European Journal of Cancer Care
https://www.readbyqxmd.com/read/28786518/the-biology-of-normal-bone-remodelling
#5
REVIEW
P Katsimbri
During life, bone undergoes modelling and remodelling in order to grow or change shape. Bone modelling is the process by which bones change shape or size in response to physiologic influences or mechanical forces that are encountered by the skeleton, while bone remodelling takes place so that bone may maintain its strength and mineral homeostasis. During early childhood, both bone modelling (the formation and shaping of bone) and bone remodelling (the replacement or renewal of old bone) occur. The predominant process in childhood is bone modelling, while in adulthood bone remodelling predominates...
August 8, 2017: European Journal of Cancer Care
https://www.readbyqxmd.com/read/28786514/cancer-and-its-impact-on-work-among-the-self-employed-a-need-to-bridge-the-knowledge-gap
#6
REVIEW
L Sharp, S Torp, E Van Hoof, A G E M de Boer
Self-employment-the so-called flexible layer of the economy-has gained importance following the 2007-2008 global economic and financial crisis. In Europe, the self-employed now comprise on average 15% of workers [Eurostat, Labour market and Labour force survey (LFS) statistics, 2016]. Around one-third of self-employed people also provide jobs for others [European Commission, Fact Sheet. 2015 Employment and Social Developments in Europe Review: frequently asked questions, 2016]. Moreover, this group of workers adapts quickly to changing circumstances...
August 8, 2017: European Journal of Cancer Care
https://www.readbyqxmd.com/read/28776784/the-international-phase-4-validation-study-of-the-eortc-qlq-swb32-a-stand-alone-measure-of-spiritual-well-being-for%C3%A2-people-receiving-palliative-care-for-cancer
#7
B Vivat, T E Young, J Winstanley, J I Arraras, K Black, F Boyle, A Bredart, A Costantini, J Guo, M E Irarrazaval, K Kobayashi, R Kruizinga, M Navarro, S Omidvari, G E Rohde, S Serpentini, N Spry, H W M Van Laarhoven, G M Yang
The EORTC Quality of Life Group has just completed the final phase (field-testing and validation) of an international project to develop a stand-alone measure of spiritual well-being (SWB) for palliative cancer patients. Participants (n = 451)-from 14 countries on four continents; 54% female; 188 Christian; 50 Muslim; 156 with no religion-completed a provisional 36-item measure of SWB plus the EORTC QLQ-C15-PAL (PAL), then took part in a structured debriefing interview. All items showed good score distribution across response categories...
August 4, 2017: European Journal of Cancer Care
https://www.readbyqxmd.com/read/28771857/reduced-employment-and-financial-hardship-among-middle-aged-individuals-with-colorectal-cancer
#8
Louisa G Gordon, Vanessa L Beesley, Gabor Mihala, Bogda Koczwara, Brigid M Lynch
Financial hardship may affect up to 30% of cancer survivors, however, little research has addressed the effect of employment change on financial hardship. This study compared the self-reported financial hardship of middle-aged (45-64 years) colorectal cancer survivors (n = 187) at 6 and 12 months following diagnosis with that of a matched general population group (n = 355). Colorectal cancer survivors were recruited through the Queensland Cancer Registry, Australia; data from the Household Income and Labour Dynamics in Australia (HILDA) Survey were used for the general population group...
August 3, 2017: European Journal of Cancer Care
https://www.readbyqxmd.com/read/28758705/coping-with-changes-and-uncertainty-a-qualitative-study-of-young-adult-cancer-patients-challenges-and-coping-strategies-during-treatment
#9
Nataskja-Elena Kersting Lie, Torill Marie Bogsnes Larsen, May Aasebø Hauken
Young adult cancer patients (YACPs), aged 18-35 years when diagnosed with cancer, are in a vulnerable transitioning period from adolescence to adulthood, where cancer adds a tremendous burden. However, YACPs' challenges and coping strategies are under-researched. The objective of this study was to explore what challenges YACP experience during their treatment, and what coping strategies they applied to them. We conducted a qualitative study with a phenomenological-hermeneutic design, including retrospective, semi-structured interviews of 16 YACPs who had undergone cancer treatment...
July 31, 2017: European Journal of Cancer Care
https://www.readbyqxmd.com/read/28748556/systemic-therapy-treatment-patterns-in-patients-with-advanced-non-small-cell-lung-cancer-nsclc-pivotal-study
#10
J de Castro, P Tagliaferri, V C C de Lima, S Ng, M Thomas, A Arunachalam, X Cao, S Kothari, T Burke, H Myeong, A Grattan, D H Lee
The aim of this multinational retrospective cohort study, conducted at academic and community oncology centres, was to describe real-world treatment patterns for patients with a confirmed diagnosis of advanced/metastatic (stage IIIB/IV) non-small cell lung cancer (NSCLC) who initiated first-line systemic therapy from January 2011 through June 2014. The study included 1265 patients in Italy, Spain, Germany, Australia, Korea, Taiwan and Brazil. The proportion of patients with squamous versus non-squamous NSCLC was approximately 20% versus 75%, and associated patient demographic characteristics were similar in all countries, excepting race...
July 27, 2017: European Journal of Cancer Care
https://www.readbyqxmd.com/read/28745015/exploring-the-provision-of-alcohol-advice-by-clinicians-to-breast-cancer-patients
#11
P Simapivapan, A Hodge, A Boltong
Interactions between clinicians and patients along the cancer trajectory provide an opportunity to deliver key messages regarding drinking behaviours and long-term health. This study aimed to explore the extent and nature of clinician-patient discussions regarding alcohol intake and cancer outcomes in the clinical breast cancer setting, using a qualitative research design involving semi-structured interviews. Purposive sampling was used to recruit 27 breast cancer clinicians (eight dietitians, nine breast care nurses, 10 oncologists) across Victoria, Australia...
July 26, 2017: European Journal of Cancer Care
https://www.readbyqxmd.com/read/28727259/developing-an-aftercare-decision-aid-assessing-health-professionals-and-patients-preferences
#12
Linda Klaassen, Carmen Dirksen, Liesbeth Boersma, Ciska Hoving
Personalising aftercare for curatively treated breast cancer patients is expected to improve patient satisfaction with care. A patient decision aid can support women in making decisions about their aftercare trajectory, but is currently not available. The aim of this study was to assess the needs of patients and health professionals with regard to an aftercare decision aid to systematically develop such a decision aid. Focus groups with patients and individual interviews with health professionals were digitally recorded and coded using the Framework analysis...
July 20, 2017: European Journal of Cancer Care
https://www.readbyqxmd.com/read/28727207/palliative-care-physicians-experiences-of-end-of-life-communication-a-focus-group-study
#13
C Udo, M Lövgren, G Lundquist, B Axelsson
The aim of this study was to explore palliative home care physicians' experiences regarding end-of-life breakpoint communication (BPC). This is a qualitative study where focus group interviews were conducted and analysed using qualitative content analysis. The results show that the participants saw themselves as being responsible for accomplishing BPC, and they were convinced that it should be regarded as a process of communication initiated at an early stage, i.e. proactively. However, BPC was often conducted as a reaction to the patient's sudden deterioration or sometimes not at all...
July 20, 2017: European Journal of Cancer Care
https://www.readbyqxmd.com/read/28707433/comparison-of-irinotecan-platinum-versus-etoposide-platinum-chemotherapy-for-extensive-stage-small-cell-lung-cancer-a-meta-analysis
#14
D Han, G Wang, L Sun, X Ren, W Shang, L Xu, S Li
This meta-analysis was performed to compare the effects and toxicities between irinotecan/platinum (IP) and etoposide/platinum (EP) regimens as the fist-line treatment of patients with extensive-stage small cell lung cancer (E-SCLC). A systematic search was made of MEDLINE, Cochrane, ISI Web of Science and SCOPUS databases. Randomised clinical trials on treatment of E-SCLC with the IP regimens, compared with EP regimens, were reviewed. Studies were pooled to hazard ratio (HR), relative risk (RR) and odds ratio (OR), with 95% confidence interval (CI)...
July 13, 2017: European Journal of Cancer Care
https://www.readbyqxmd.com/read/28707369/psychological-stress-affects-the-severity-of-radiation-induced-acute-skin-reactions-in-breast-cancer-patients
#15
A E Sutherland, N C Bennett, P M Herst
Psychological stress exacerbates many pathological conditions including inflammatory skin conditions. The effect of psychological stress on acute radiation-induced skin reactions has not been documented before. Here, we aimed to explore if psychological stress could aggravate skin reaction severity in breast cancer patients. We conducted a secondary analysis of patient data obtained during a randomised, controlled clinical trial for acute radiation-induced skin reaction severity in 78 breast cancer patients...
July 13, 2017: European Journal of Cancer Care
https://www.readbyqxmd.com/read/28675545/cost-effectiveness-analysis-of-fulvestrant-versus-anastrozole-as-first-line-treatment-for-hormone-receptor-positive-advanced-breast-cancer
#16
H Ding, L Fang, W Xin, Y Tong, Q Zhou, P Huang
Although recent studies demonstrated that fulvestrant is superior to anastrozole as first-line treatment for hormone receptor (HR)-positive advanced breast cancer, the cost-effectiveness of fulvestrant versus anastrozole remained uncertain. Thus, the current study aimed to evaluate the cost-effectiveness of fulvestrant compared with anastrozole in the first-line setting. A Markov model consisting of three health states (stable, progressive and dead) was constructed to simulate a hypothetical cohort of patients with HR-positive advanced breast cancer...
July 3, 2017: European Journal of Cancer Care
https://www.readbyqxmd.com/read/28671297/standardisation-of-minimal-residual-disease-in-multiple-myeloma
#17
V Innao, A Allegra, S Russo, D Gerace, D Vaddinelli, A Alonci, A G Allegra, C Musolino
The assessment of the effectiveness of chemotherapy in oncology cannot disregard the concept of minimal residual disease (MRD). In fact, the efforts of numerous scientific groups all over the world are currently focusing on this issue, with the sole purpose of defining sensitive, effective assessment criteria that are, above all, able to give acceptable, easily repeatable results worldwide. Regarding this issue, especially with the advent of new drugs, multiple myeloma is one of the haematologic malignancies for which a consensus has not yet been reached...
July 3, 2017: European Journal of Cancer Care
https://www.readbyqxmd.com/read/28653449/the-value-of-biomarkers-in-bone-metastasis
#18
Stella D'Oronzo, Janet Brown, Robert Coleman
The worst complication of cancer is represented by its spread to distant sites. In particular, bone provides a fertile soil for several cancer types, especially those derived from breast, prostate and lung tumours. Despite the progress in diagnostic and therapeutic strategies, bone metastases (BM) still impact on quality of life and overall survival, making it necessary to identify the "high-risk" patients at an earlier stage. Since BM affect physiological bone turnover, measurement of bone turnover markers (BTM) has been widely investigated for diagnostic and prognostic purposes, as well as to support the development of anti-cancer drugs...
June 27, 2017: European Journal of Cancer Care
https://www.readbyqxmd.com/read/28639355/how-do-the-characteristics-of-breast-cancer-diagnostic-assessment-programmes-influence-service-delivery-a-mixed-methods-study
#19
A R Gagliardi, G Honein-AbouHaidar, T Stuart-McEwan, J Smylie, A Arnaout, J Seely, F C Wright, M J Dobrow, M C Brouwers, K Bukhanov, D R McCready
Diagnostic assessment programmes (DAPs) coordinate multidisciplinary teamwork (MDT), and improve wait times and patient satisfaction. No research has established optimal DAP design. This study explored how DAP characteristics influence service delivery. A mixed methods case study of four breast cancer DAPs was conducted including qualitative interviews with health-care providers and retrospective chart review. Data were integrated using multiple approaches. Twenty-three providers were interviewed; 411 medical records were reviewed...
June 21, 2017: European Journal of Cancer Care
https://www.readbyqxmd.com/read/28631284/the-role-of-radiotherapy-in-bone-metastases-a-critical-review-of-current-literature
#20
REVIEW
A Kougioumtzopoulou, A Zygogianni, Z Liakouli, E Kypraiou, V Kouloulias
Radiotherapy is considered the treatment of choice for painful bone metastases. However, novel modalities of radiotherapy have emerged in the concept of oligometastasic disease. In addition, the increase of overall survival of patients with bone metastatic disease in the last decades due to systemic treatments has issued the silent topic of re-irradiation. The aim of this manuscript was to present a current thorough search of relevant literature. Originally, 6,087 articles revealed from PubMed database related to radiotherapy and bone metastases...
June 20, 2017: European Journal of Cancer Care
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