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Blood Pressure

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https://www.readbyqxmd.com/read/28643526/association-between-cotinine-verified-smoking-status-and-hypertension-in-167-868-korean-adults
#1
Byung Jin Kim, Ji Min Han, Jung Gyu Kang, Bum Soo Kim, Jin Ho Kang
PURPOSE: Previous studies showed inconsistent results concerning the relationship between chronic smoking and blood pressure. Most of the studies involved self-reported smoking status. This study was performed to evaluate the association of urinary cotinine or self-reported smoking status with hypertension and blood pressure in Korean adults. MATERIALS AND METHODS: Among individuals enrolled in the Kangbuk Samsung Health Study and Kangbuk Samsung Cohort Study, 167,868 participants (men, 55...
June 23, 2017: Blood Pressure
https://www.readbyqxmd.com/read/28595464/the-effects-of-baroreflex-activation-therapy-on-blood-pressure-and-sympathetic-function-in-patients-with-refractory-hypertension-the-rationale-and-design-of-the-nordic-bat-study
#2
Daniel Gordin, Fadl Elmula M Fadl Elmula, Bert Andersson, Anders Gottsäter, Johan Elf, Thomas Kahan, Kent Lodberg Christensen, Pirkka Vikatmaa, Leena Vikatmaa, Thomas Bastholm Olesen, Per-Henrik Groop, Michael Hecht Olsen, Ilkka Tikkanen
OBJECTIVE: To explore the effects of baroreflex activation therapy (BAT) on hypertension in patients with treatment resistant or refractory hypertension. METHODS: This investigator-initiated randomized, double-blind, 1:1 parallel-design clinical trial will include 100 patients with refractory hypertension from 6 tertiary referral hypertension centers in the Nordic countries. A Barostim Neo System will be implanted and after 1 month patients will be randomized to either BAT for 16 months or continuous pharmacotherapy (BAT off) for 8 months followed by BAT for 8 months...
June 8, 2017: Blood Pressure
https://www.readbyqxmd.com/read/28524699/comparison-of-ambulatory-blood-pressure-lowering-effects-of-higher-doses-of-different-calcium-antagonists-in-uncontrolled-hypertension-the-calcium-antagonist-controlled-release-high-dose-therapy-in-uncontrolled-refractory-hypertensive-patients-carillon-study
#3
Hiroyuki Mizuno, Satoshi Hoshide, Naoko Tomitani, Kazuomi Kario
BACKGROUND: Data are sparse regarding ambulatory blood pressure (BP) reduction of up-titration from a standard dose to a high dose in both nifedipine controlled-release (CR) and amlodipine. This was a prospective, randomized, multicenter, open-label trial. PATIENTS AND METHODS: Fifty-one uncontrolled hypertensives medicated by two or more antihypertensive drugs including a renin-angiotensin system inhibitor and a calcium antagonist were randomly assigned to either the nifedipine CR (80 mg)/candesartan (8 mg) group or the amlodipine (10 mg)/candesartan (8 mg) group...
May 19, 2017: Blood Pressure
https://www.readbyqxmd.com/read/28489464/results-of-a-randomized-controlled-pilot-trial-of-intravascular-renal-denervation-for-management-of-treatment-resistant-hypertension
#4
Lotte Jacobs, Alexandre Persu, Qi-Fang Huang, Jean-Philippe Lengelé, Lutgarde Thijs, Frank Hammer, Wen-Yi Yang, Zhen-Yu Zhang, Jean Renkin, Peter Sinnaeve, Fang-Fei Wei, Agnès Pasquet, Fadl Elmula M Fadl Elmula, Marc Carlier, Arif Elvan, Cora Wunder, Sverre E Kjeldsen, Stefan W Toennes, Stefan Janssens, Peter Verhamme, Jan A Staessen
OBJECTIVE: Previous trials of catheter-based renal-artery denervation (RDN) as treatment modality in resistant hypertension (rHT) generated unconvincing results. In the Investigator-Steered Project on Intravascular Denervation for Management of Treatment-Resistant Hypertension (INSPiRED; NCT01505010), we optimized selection and management of rHT patients. METHODS: With ethical clearance to randomize 18 patients, three Belgian hypertension centers screened 29 rHT patients on treatment with ≥3 drugs, of whom 17 after optimization of treatment (age <70 years; systolic/diastolic office blood pressure (BP) ≥ 140/90 mm Hg; 24-h BP ≥130/80 mm Hg; glomerular filtration rate [eGFR] ≥ 45 mL/min/1...
May 10, 2017: Blood Pressure
https://www.readbyqxmd.com/read/28443356/sham-or-no-sham-control-that-is-the-question-in-trials-of-renal-denervation-for-resistant-hypertension-a-systematic-meta-analysis
#5
Fadl Elmula M Fadl Elmula, Ying-Mei Feng, Lotte Jacobs, Anne C Larstorp, Sverre E Kjeldsen, Alexandre Persu, Jan A Staessen
BACKGROUND: Studies of renal denervation (RDN) in patients with apparent treatment resistant hypertension have been hampered by a number of patient and physician related confounders on blood pressure (BP) including poor drug adherence. It remains uncertain whether RDN lowers BP. We aimed to investigate whether the use of sham control is essential in RDN studies or whether systematic use of 24-hour ambulatory BP provides enough information thereby making an invasive sham control redundant...
April 26, 2017: Blood Pressure
https://www.readbyqxmd.com/read/28385080/blood-pressure-control-in-anticoagulated-patients-with-hypertension-and-atrial-fibrillation
#6
Vivencio Barrios, Carlos Escobar, Luis Prieto Valiente, Jose María Lobos, Diego Vargas-Ortega, Jose Polo, Nuria Marin Montañés
OBJECTIVE: To determine the clinical profile and blood pressure (BP) control rates of anticoagulated patients with hypertension and atrial fibrillation (AF). METHODS: The PAULA study was a multicenter cross-sectional/retrospective observational study conducted throughout Spain. The study included patients with nonvalvular AF who were receiving vitamin K antagonist therapy during the past year and were attended at primary care setting. Adequate BP control was defined according to 2013 ESC/ESH guidelines...
April 7, 2017: Blood Pressure
https://www.readbyqxmd.com/read/28376650/office-blood-pressure-measurements-with-oscillometric-devices-in-adolescents-a-comparison-with-home-blood-pressure
#7
Thiago Veiga Jardim, Thomas A Gaziano, Flávia Miquetichuc Nascente, Carolina de Souza Carneiro, Polyana Morais, Vanessa Roriz, Karla Lorena Mendonça, Thaís Inácio Rolim Póvoa, Weimar Kunz Sebba Barroso, Ana Luiza Lima Sousa, Paulo César Veiga Jardim
PURPOSE: Compare multiple in office BP measurements in adolescents using an oscillometric device with out-of-office blood pressure measurements (home blood pressure monitoring - HBPM). MATERIALS AND METHODS: Office measurements were performed with validated semi-automatic devices twice (3 minutes interval) in two different moments (1 week apart), with a total of four readings. These BP readings were named R1, R2, R3 and R4 (following the sequence they were performed), FDM (mean of two readings on first day) and SDM (mean of two readings on second day) and SRM (R2-R4 means)...
April 4, 2017: Blood Pressure
https://www.readbyqxmd.com/read/28566004/prevention-of-heart-failure-mortality-and-hospitalizations-in-sprint-empa-reg-allhat-and-hyvet-are-diuretics-the-clue
#8
Michel Burnier, Krzysztof Narkiewicz, Sverre E Kjeldsen
No abstract text is available yet for this article.
August 2017: Blood Pressure
https://www.readbyqxmd.com/read/28224820/the-interstroke-study-hypertension-is-by-far-the-most-important-modifiable-risk-factor-for-stroke
#9
Sverre E Kjeldsen, Krzysztof Narkiewicz, Michel Burnier, Suzanne Oparil
No abstract text is available yet for this article.
June 2017: Blood Pressure
https://www.readbyqxmd.com/read/28116919/morning-blood-pressure-surge-and-arterial-stiffness-in-newly-diagnosed-hypertensive-patients
#10
Ali Kıvrak, Süleyman Özbiçer, Gülhan Yüksel Kalkan, Mustafa Gür
OBJECTIVE: We aimed to investigate the relationship between the morning blood pressure (BP) surge and arterial stiffness in patients with newly diagnosed hypertension. SUBJECTS AND METHODS: Three hundred and twenty four (mean age 51.7 ± 11.4 years) patients who had newly diagnosed hypertension with 24 h ambulatory BP monitoring were enrolled. Parameters of arterial stiffness, pulse wave velocity and augmentation index (Aix) were measured by applanation tonometry and aortic distensibility was calculated by echocardiography...
June 2017: Blood Pressure
https://www.readbyqxmd.com/read/28092977/hypertension-is-associated-with-increased-mortality-in-patients-with-ischaemic-heart-disease-after-revascularization-with-percutaneous-coronary-intervention-a-report-from-scaar
#11
Ott Saluveer, Björn Redfors, Oskar Angerås, Christian Dworeck, Inger Haraldsson, Charlotta Ljungman, Petur Petursson, Jacob Odenstedt, Dan Ioanes, Peter Lundgren, Sebastian Völz, Truls Råmunddal, Bert Andersson, Elmir Omerovic, Niklas Bergh
BACKGROUND: The prognostic role of hypertension on long-term survival after percutaneous coronary intervention (PCI) is limited and inconsistent. We hypothesize that hypertension increases long-term mortality after PCI. METHODS: We analyzed data from SCAAR (Swedish Coronary Angiography and Angioplasty Registry) for all consecutive patients admitted coronary care units in Sweden between January 1995 and May 2013 and who underwent PCI due to ST-elevation myocardial infarction (STEMI), non-ST-elevation myocardial infarction (NSTEMI)/unstable angina (UA) or stable angina pectoris...
June 2017: Blood Pressure
https://www.readbyqxmd.com/read/28092973/elevated-ambulatory-systolic-diastolic-pressure-regression-index-is-genetically-determined-in-hypertensive-patients-with-coronary-heart-disease
#12
Marcin Wirtwein, Olle Melander, Marketa Sjőgren, Michal Hoffmann, Krzysztof Narkiewicz, Marcin Gruchala, Wojciech Sobiczewski
OBJECTIVES: Ambulatory systolic-diastolic pressure regression index (ASDPRI) as a composite marker of cardiovascular (CV) properties is related to CV complications. However, genetic determinants of ASDPRI are not known. The aim of this study is to report the relationship between certain single nucleotide polymorphisms (SNP) and ASDPRI in hypertensive patients with CAD confirmed by coronary angiography. METHODS: A total of 1345 hypertensive subjects with CAD were included...
June 2017: Blood Pressure
https://www.readbyqxmd.com/read/28078909/apparent-treatment-resistant-hypertension-patient-physician-relationship-and-ethical-issues
#13
REVIEW
Julian E Mariampillai, Per Anders Eskås, Sondre Heimark, Anne Cecilie K Larstorp, Fadl Elmula M Fadl Elmula, Aud Høieggen, Per Nortvedt
BACKGROUND: Poor drug adherence is a major cause of apparent treatment-resistant hypertension. As a consequence, several methods have been developed and attempted implemented in clinical practice to reveal non-adherence and to monitor drug adherence. There are, however, several hitherto unresolved ethical aspects regarding potential methods for drug monitoring in these patients. RESULTS: The most striking challenge is the balance between patient autonomy and the physician's desire for the patient to adhere to the prescribed therapy...
June 2017: Blood Pressure
https://www.readbyqxmd.com/read/28027698/hypertension-and-functional-capacities-in-community-dwelling-older-women-a-cross-sectional-study
#14
Hélio José Coelho Junior, Bruno Rodrigues, Samuel da Silva Aguiar, Ivan de Oliveira Gonçalves, Flávio de Oliveira Pires, Ricardo Yukio Asano, Marco Carlos Uchida
PURPOSE: The present study aimed to investigate the association between hypertension and physical/functional capacities in community-dwelling older females. MATERIALS AND METHODS: Older female volunteers were dichotomized in two groups: hypertensive (n = 134) and normotensive (n = 244). Volunteers had their medical records reviewed and underwent evaluations of anthropometric data (weight, height and body mass index) and of physical and functional capacities...
June 2017: Blood Pressure
https://www.readbyqxmd.com/read/27808564/endothelin-receptor-antagonist-can-reduce-blood-pressure-in-patients-with-hypertension-a-meta-analysis
#15
Wenming Yuan, Genyang Cheng, Bin Li, Yansheng Li, Shan Lu, Dong Liu, Jing Xiao, Zhanzheng Zhao
The aim of this meta-analysis was to assess the effectiveness and safety of endothelin-receptor antagonist (ERA) in the patients with hypertension. Searches of the PubMed, EMBASE, and CENTRAL databases were conducted to include all the randomized control trials (RCTs). Eighteen trials including 4898 patients were used in the meta-analysis, of which nine were classified as low risk of bias and the other nine as unclear risk of bias. There was no statistically significant difference in all-cause mortality between ERA and placebo groups [6 trials, fixed effects model, RR 1...
June 2017: Blood Pressure
https://www.readbyqxmd.com/read/27710139/higher-pulse-pressure-stroke-volume-index-is-associated-with-impaired-outcome-in-hypertensive-patients-with-left-ventricular-hypertrophy-the-life-study
#16
RANDOMIZED CONTROLLED TRIAL
Costantino Mancusi, Eva Gerdts, Giovanni de Simone, Helga Midtbø, Mai Tone Lønnebakken, Kurt Boman, Kristian Wachtell, Björn Dahlöf, Richard B Devereux
We tested the prognostic impact of a marker of arterial stiffness, pulse pressure/stroke volume index (PP/SVi), in patients with hypertension and left ventricular (LV) hypertrophy. We used data from 866 patients randomized to losartan or atenolol-based antihypertensive treatment, over a median of 4.8 years, in the Losartan Intervention For Endpoint reduction in hypertension (LIFE) study. The association of PP/SVi with outcomes was tested in Cox regression analyses and reported as hazard ratio (HR) and 95% confidence intervals (CI)...
June 2017: Blood Pressure
https://www.readbyqxmd.com/read/28049345/the-intersalt-study-and-the-complex-relationship-between-salt-intake-and-blood-pressure
#17
EDITORIAL
Sverre E Kjeldsen, Krzysztof Narkiewicz, Michel Burnier, Suzanne Oparil
No abstract text is available yet for this article.
April 2017: Blood Pressure
https://www.readbyqxmd.com/read/27825280/crosstalk-between-obesity-and-mmp-9-in-cardiac-remodelling-a-cross-sectional-study-in-apparent-treatment-resistant-hypertension
#18
COMPARATIVE STUDY
Alessandra Mileni Versuti Ritter, Ana Paula de Faria, Natália Barbaro, Andréa Rodrigues Sabbatini, Nathália Batista Corrêa, Veridiana Brunelli, Rivadavio Amorim, Rodrigo Modolo, Heitor Moreno
The balance between matrix metalloproteinases (MMP) and their tissue inhibitors (TIMP) plays a key role in the development of hypertension and obesity. We aimed to evaluate the levels of MMP-2 and 9 and TIMP-2 and -1 in obese and non-obese apparent treatment-resistant hypertensive subjects (aTRH) and its association with cardiac hypertrophy. This cross-sectional study enrolled 122 subjects and divided into obese aTRH (n = 67) and non-obese (n = 55) group. Clinical and biochemical data were compared between both groups, including office BP, ambulatory BP, plasma MMP-2 and 9, TIMP-2 and 1 and left ventricular mass index (LVMI)...
April 2017: Blood Pressure
https://www.readbyqxmd.com/read/27653044/arterial-stiffness-is-not-increased-in-patients-with-short-duration-rheumatoid-arthritis-and-ankylosing-spondylitis
#19
Anna Dzieża-Grudnik, Joanna Sulicka, Magdalena Strach, Olga Siga, Ewa Klimek, Mariusz Korkosz, Tomasz Grodzicki
Patients with rheumatoid arthritis (RA) and ankylosing spondylitis (AS) have increased cardiovascular (CV) morbidity and mortality. Arterial stiffness is an independent predictor of CV events. The aim of the study was to assess arterial stiffness and inflammatory markers in patients with short duration chronic arthritis. We assessed carotid-femoral pulse wave velocity (PWV), augmentation index (AIx), traditional CV risk factors and inflammatory and endothelial markers in 71 chronic arthritis patients (RA and AS) and in 29 healthy controls...
April 2017: Blood Pressure
https://www.readbyqxmd.com/read/27601201/performance-of-targeted-screening-for-the-identification-of-hypertension-in-children
#20
Clemens Bloetzer, Pascal Bovet, Fred Paccaud, Michel Burnier, Arnaud Chiolero
Targeted screening of hypertension in childhood might be more efficient than universal screening. We estimated the sensitivity, specificity, negative and positive predictive values of combined parental history of hypertension and overweight/obesity for the diagnosis of hypertension in 5207 children aged 10-14 years. Children had hypertension if they had sustained elevated blood pressure over three separate visits. The prevalence of hypertension was 2.2%. 14% of children were overweight or obese, 20% had a positive history of hypertension in at least one parent and 30% had either or both conditions...
April 2017: Blood Pressure
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