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Transfusion Medicine

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https://www.readbyqxmd.com/read/30209836/circulating-plasma-micrornas-as-biomarkers-for-iron-status-in-blood-donors
#1
M G Gunnarsdottir, T Jonsson, A M Halldorsdottir
OBJECTIVES: To investigate whether microRNAs can serve as biomarkers for iron status in blood donors. BACKGROUND: Serum ferritin is a widely used biochemical test for detecting iron deficiency, but it has its limitations. Certain microRNAs (miRNAs) reportedly have a role in regulating iron homeostasis. Circulating miRNAs have been reported as potential biomarkers for various conditions but have not yet been studied in iron deficiency. METHODS: Participating blood donors were divided into two groups: high ferritin (HF) (>150 µg L-1 ) and low ferritin (LF) (<15 µg L-1 )...
September 12, 2018: Transfusion Medicine
https://www.readbyqxmd.com/read/30209833/transfusion-knowledge-of-medical-and-surgical-specialty-board-residents-a-cohort-study
#2
A Z Al-Riyami, I Al-Nomani, S M Panchatcharam, L Wadsworth, M Al-Khabori, K Al-Farsi, H Al-Sabti
OBJECTIVES: This study was conducted to assess transfusion knowledge between different specialty board residents and to identify areas of need for further education. BACKGROUND: Physicians' knowledge of transfusion medicine (TM) is critical for patients' safety. Many clinicians who are involved in day-to-day transfusion practice have little or no formal training in TM. There are no studies to assess physician's TM knowledge locally. METHODS: A comprehensive anonymous survey was developed to assess baseline TM knowledge of all the residents...
September 12, 2018: Transfusion Medicine
https://www.readbyqxmd.com/read/30144204/the-red-blood-cell-unit-and-ice-configuration-in-portable-coolers-is-important-in-maintaining-acceptable-storage-air-temperature
#3
LETTER
Z Ye, M H Yazer, D J Triulzi
No abstract text is available yet for this article.
August 24, 2018: Transfusion Medicine
https://www.readbyqxmd.com/read/30144203/socio-epidemiological-characterisation-of-blood-donors-with-asymptomatic-leishmania-infantum-infection-from-three-brazilian-endemic-regions-and-analysis-of-the-transfusional-transmission-risk-of-visceral-leishmaniasis
#4
M M Ferreira-Silva, L A S Teixeira, M S Tibúrcio, G A Pereira, V Rodrigues, M Palis, P Afonso, M Alves, J M Feitosa, E Urias, E M Santos, S F G Carvalho, H Moraes-Souza
OBJECTIVES: This study assessed the prevalence of visceral leishmaniasis in blood donors from three endemic regions in Brazil and evaluated the risk of transmission by transfusion. BACKGROUND: Despite strong evidence of the transmission of visceral leishmaniasis through blood transfusion, the real risk, an essential condition for taking effective measures to control this serious disease, has not been determined. METHODS: A multicentre study was performed in highly endemic areas...
August 24, 2018: Transfusion Medicine
https://www.readbyqxmd.com/read/30074281/sero-prevalence-and-viremia-status-of-dengue-virus-among-asymptomatic-blood-donors-post-epidemic-outbreak-in-chinese-guangzhou-in-2015
#5
LETTER
P Zeng, Q Liao, Z Gao, M He, X Rong
No abstract text is available yet for this article.
August 3, 2018: Transfusion Medicine
https://www.readbyqxmd.com/read/29873421/thrombocytopenia-secondary-to-passive-transfer-of-anti-hpa-1a-antibodies-from-male-donor-plasma
#6
LETTER
F Swain, S Baidya, J Casey, R Francis, G Pahn, M Burton, P Hassell, K Havelberg, G Jones, D Mahon, R Holdsworth
No abstract text is available yet for this article.
June 6, 2018: Transfusion Medicine
https://www.readbyqxmd.com/read/29873420/multiple-miscarriages-in-two-sisters-of-thai-origin-with-the-rare-p-k-phenotype-caused-by-a-novel-nonsense-mutation-at-the-b3galnt1-locus
#7
J Ricci Hagman, A K Hult, J S Westman, B Hosseini-Maaf, P Jongruamklang, J Saipin, S Bejrachandra, M L Olsson
OBJECTIVES: To determine the genetic background underlying the Pk phenotype in two Thai sisters suffering from multiple spontaneous abortions. BACKGROUND: The P antigen is carried by globoside, an abundant glycosphingolipid in the red blood cell (RBC) membrane. Inactivating mutations in the 3-β-N-acetylgalactosaminyltransferase gene (B3GALNT1) give rise to the rare Pk phenotype, which lack the P and PX2 antigens. Consequently, naturally occurring anti-P may cause recurrent miscarriages following the cytotoxic attack of the globoside-rich fetal portion of the placenta...
June 6, 2018: Transfusion Medicine
https://www.readbyqxmd.com/read/28940904/genotyping-of-the-abcg2-gene-using-matrix-associated-laser-desorption-ionisation-time-of-flight-mass-spectrometry
#8
M Tanaka, I Kamada, J Takahashi, T Kimura, Y Tani
OBJECTIVES: The aim of this study was to evaluate the applicability of genotyping of the ABCG2 gene using MALDI-TOF MS and to estimate the allele frequency in the Japanese population. BACKGROUND: Jr (a-) phenotype has a prevalence of approximately 0·05% among Japanese blood donors; DNA-based genotyping was conducted to investigate the molecular basis of the Jr (a-) phenotype along with serological typing. To detect all SNPs of the ABCG2 gene, a high-throughput SNP genotyping platform is needed...
June 2018: Transfusion Medicine
https://www.readbyqxmd.com/read/28913856/multiplate-and-teg-platelet-mapping-in-a-population-of-severely-injured-trauma-patients
#9
M J George, J Burchfield, B MacFarlane, Y-W W Wang, J C Cardenas, N J White, B S Gill, C E Wade
OBJECTIVES: The objectives of this study were to compare thromboelastography platelet mapping (TEG PM) with impedance aggregometry (Multiplate, MP) in a single trauma population and relate their results clinically. BACKGROUND: Platelet function as measured by thromboelastography and impedance aggregometry demonstrates significant reductions that persist for days following traumatic injury. However, no study compares these devices and the correlation between them is not known...
June 2018: Transfusion Medicine
https://www.readbyqxmd.com/read/28875563/theoretical-and-experimental-ethics-advocacy-for-blood-donors-and-beneficiaries-of-blood-transfusions
#10
LETTER
O Garraud, J-D Tissot
No abstract text is available yet for this article.
June 2018: Transfusion Medicine
https://www.readbyqxmd.com/read/28833874/use-of-granulocyte-transfusions-among-haematology-units-in-england-and-north-wales
#11
S Morton, A Mijovic, D I Marks, J Griffin, E Massey, N Bhatnagar, S J Stanworth
OBJECTIVES: To establish the current use of granulocyte transfusions in haematology patients and explore interest in further research. BACKGROUND: Granulocytes may be used for the treatment of severe infection in neutropenic patients or for primary or secondary prophylaxis. Clinical utility of granulocyte transfusions is unclear, and recent studies have demonstrated equivocal outcomes. Pooled granulocytes are the main granulocyte product used in England and Wales, but there are no data on the patterns of use and little consensus on accepted indications...
June 2018: Transfusion Medicine
https://www.readbyqxmd.com/read/28804958/prevalence-of-hepatitis-b-and-human-t-lymphotropic-virus-infection-among-blood-donors-at-a-hospital-in-the-south-central-highlands-of-peru
#12
LETTER
M C Ramírez-Soto, M Huichi-Atamari
No abstract text is available yet for this article.
June 2018: Transfusion Medicine
https://www.readbyqxmd.com/read/28758700/dengue-virus-infections-among-blood-donors-in-guangxi-of-china-2013-2014
#13
Z Gao, Y Zhang, Y Yang, M Xu, P Liao, W He, J Xu, Y Liu, M He
BACKGROUND: An unexpected, large dengue outbreak, spreading to 20 cities of Guangdong province, occurred in July 2014. Considering the overwhelming influence of this seasonal epidemic, whether this dengue virus outbreak has an significant impact on the blood donors of the ajacent areas in Guangdong requires at least a preliminary investigation. Liuzhou City of Guangxi was chosen as a good representative of the neighbouring geographical location of the dengue virus (DENV) outbreak areas in this research...
June 2018: Transfusion Medicine
https://www.readbyqxmd.com/read/28749037/transfusion-for-sickle-cell-disease-in-pregnancy-a-single-centre-survey
#14
J Sharif, L Byrd, K Stevenson, J Raddats, E Morsman, K Ryan
INTRODUCTION: Sickle cell disease in pregnancy carries a high risk of maternal and fetal adverse outcomes. The use of prophylactic transfusions to reduce the risk of sickle complications is controversial. Current UK standards do not recommend the routine use of transfusion for sickle pregnancy. We examined transfusion episodes during sickle pregnancies in a single centre over an 11-year period. METHODS: We conducted a retrospective observational study of all pregnancies in patients with sickle cell disease who attended the joint obstetric/haematology clinic over an 11-year period...
June 2018: Transfusion Medicine
https://www.readbyqxmd.com/read/28722278/non-physician-health-care-workers-and-voluntary-blood-donation-an-ambiguous-relationship
#15
N Sousos, S Sfyridou, D Adamidou, T-A Vyzantiadis, M Karadosidou, A Filippou, T Karafoulidou, M Chouridi, S Theodoridou
OBJECTIVES: This study aims to assess the knowledge, attitude and practice (KAP) of voluntary blood donation (BD) among the non-physician health-care workers of our institution, to investigate the relationship between these parameters and to determine the predictors of BD practice. BACKGROUND: KAP surveys provide a popular context-specific evidence base for the development of blood transfusion services' strategies and interventions to promote voluntary, non-remunerated BD...
June 2018: Transfusion Medicine
https://www.readbyqxmd.com/read/28677305/reasons-to-end-the-donor-career-a-quantitative-study-among-stopped-blood-donors-in-the-netherlands
#16
E F Klinkenberg, B Romeijn, W L de Kort, E-M Merz
BACKGROUND AND OBJECTIVES: Previous work has studied barriers to donating blood or plasma among current, lapsed and non-donors. Still, it remains unclear why donors stop donating and end their donor career voluntarily. A thorough understanding of why donors stop is necessary to develop more effective retention strategies and manage the decline in whole-blood donors. METHODS: An online questionnaire that contained questions about reasons to stop donation was sent out to 7098 Dutch whole-blood donors who deregistered from the donor pool in 2015 but who were not permanently deferred for medical reasons (response: N = 2490, 35%)...
June 2018: Transfusion Medicine
https://www.readbyqxmd.com/read/28661062/randomised-feasibility-study-of-a-more-liberal-haemoglobin-trigger-for-red-blood-cell-transfusion-compared-to-standard-practice-in-anaemic-cancer-patients-treated-with-chemotherapy
#17
D Yakymenko, K B Frandsen, I J Christensen, A Norgaard, P I Johansson, G Daugaard, M Mau-Sorensen
OBJECTIVES: The primary objective of this feasibility study was to identify quality of life (QoL) scores and symptom scales as tools for measuring patient-reported outcomes (PRO) associated with haemoglobin level in chemotherapy-treated cancer patients. Secondary objectives included comparing QoL and symptoms between randomisation arms. BACKGROUND: Anaemia in cancer patients undergoing chemotherapy is associated with decreased QoL. One treatment option is red blood cell transfusion (RBCT)...
June 2018: Transfusion Medicine
https://www.readbyqxmd.com/read/28557101/the-association-between-interval-from-acceptance-to-first-time-donation-missed-first-appointment-and-future-donation-behaviour
#18
S A Mousavi, B Hermundstad, T R Knutsen, A H Llohn
BACKGROUND AND OBJECTIVES: We examined the association of the interval between the date an individual is accepted for blood donation and the date of first donation (IFD-interval, index-to-first-time donation interval) and missed first appointment with future donation behaviour among new donors. These two variables have not been analysed in previous studies of donation behaviour among new donors. METHODS: Categories were generated for age (18-29 vs 30-65 years), missed-appointment status (no-show vs same-day cancellation) and the IFD-interval [short (≤median time) vs long (>median time)]...
June 2018: Transfusion Medicine
https://www.readbyqxmd.com/read/28524621/a-fatal-case-of-autoanti-wr-b-causing-autoagglutination-of-red-blood-cells-and-intravascular-haemolysis
#19
LETTER
K Maguire, K Morris, M Quinn, B Herron, A Rainey, N Thornton
No abstract text is available yet for this article.
June 2018: Transfusion Medicine
https://www.readbyqxmd.com/read/28516464/the-blood-donation-ambivalence-survey-measuring-conflicting-attitudes-about-giving-blood
#20
K R Fox, L K Himawan, C R France
OBJECTIVES: This study was designed to develop and conduct initial validation testing for a novel measure of ambivalence about donating blood. BACKGROUND: Previous studies of living organ, bone marrow and stem cell donors have identified donation-related ambivalence as a predictor of decisions about donation and post-donation outcomes. Ambivalence about blood donation has not received the same attention. METHODS: In Study 1, a sample of young adults (N = 396) were administered test items of ambivalence, and exploratory (EFA) and confirmatory factor analyses (CFA) were performed to identify the Blood Donation Ambivalence Survey...
June 2018: Transfusion Medicine
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