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Transfusion Medicine

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https://www.readbyqxmd.com/read/27873379/oxford-s-systematic-review-initiative-leading-by-example-in-evidence-based-transfusion-medicine
#1
D A Fergusson
No abstract text is available yet for this article.
November 22, 2016: Transfusion Medicine
https://www.readbyqxmd.com/read/27859798/how-to-encourage-non-donors-to-be-more-willing-to-donate-blood-testing-of-binding-communication-based-interventions
#2
D Fonte, J Blondé, F Girandola
OBJECTIVES: Our study aims to test the effectiveness of binding communication based interventions (vs classical persuasive communication based ones) inciting non-donors to act in favour of blood donation. BACKGROUND: The implementation of effective communication interventions represents a major public health issue. Nevertheless, persuasive media campaigns appear to have little effect on behaviours. Even though non-donors hold a positive attitude towards blood donation, they are not inclined to donate...
November 10, 2016: Transfusion Medicine
https://www.readbyqxmd.com/read/27862486/characterisation-of-maternal-human-leukocyte-antigen-class-i-antibodies-in-suspected-foetal-and-neonatal-alloimmune-thrombocytopenia
#3
E Refsum, A Mörtberg, J Dahl, S Meinke, M-K Auvinen, M Westgren, M Reilly, P Höglund, A Wikman
OBJECTIVES: To investigate the specificities and level of HLA class I antibodies in selected cases referred for suspected foetal and neonatal alloimmune thrombocytopenia (FNAIT). BACKGROUND: FNAIT occurs in 1 : 1-2000 live births, whereas maternal immunisation against human leukocyte antigen (HLA) class I is common. Whether HLA class I antibodies alone can cause FNAIT is debatable. MATERIAL AND METHODS: A total of 260 patient samples were referred between 2007 and 2012...
November 9, 2016: Transfusion Medicine
https://www.readbyqxmd.com/read/27730692/frequency-and-reasons-of-donor-deferral-prior-to-blood-donation-process-a-single-centre-experience
#4
S Khurram, M Borhany, N Anwar, I Naseer, S Boota, I Mirza, M Nadeem, T Shamsi
OBJECTIVE: The aim of the study was to determine the frequency and reasons for donor deferral prior to the blood donation process in our population. BACKGROUND: Transfusion is an irreversible event that carries potential risks as well as benefits to the recipient. Therefore, donor selection prior to blood donation is one of the most important steps in ensuring the safety of blood and blood products. METHODS: A cross-sectional study was carried out at the blood bank department in our hospital from January 2012 to December 2014...
October 12, 2016: Transfusion Medicine
https://www.readbyqxmd.com/read/27730689/measurement-of-haemolysis-markers-following-transfusion-of-uncrossmatched-low-titer-group-o-whole-blood-in-civilian-trauma-patients-initial-experience-at-a-level-1-trauma-centre
#5
J N Seheult, D J Triulzi, L H Alarcon, J L Sperry, A Murdock, M H Yazer
BACKGROUND/OBJECTIVES: The safety of administering uncrossmatched, group O, cold-stored, whole blood (cWB) during civilian trauma resuscitation was evaluated. METHODS/MATERIALS: Male trauma patients with haemorrhage-induced hypotension who received leuko-reduced uncrossmatched group O+, low titer (<50) anti-A and -B, platelet-replete cWB during initial resuscitation were included. The biochemical markers of haemolysis (lactate dehydrogenase, total bilirubin, haptoglobin, creatinine, serum potassium) were measured on the day of cWB receipt (day 0), and over the next 2 days, reports of transfusion reactions and total blood product administration in first 24 h of admission were recorded...
October 12, 2016: Transfusion Medicine
https://www.readbyqxmd.com/read/27726235/performance-assessment-and-benchmarking-of-autologous-peripheral-blood-stem-cell-collection-with-two-different-apheresis-devices
#6
P Wuchter, M Hundemer, A Schmitt, M Witzens-Harig, P Pavel, J Hillengass, H Goldschmidt, A D Ho, K Lisenko
BACKGROUND: Collection of peripheral blood stem cells (PBSCs) for autologous transplantation is a well-established process. As a new generation of leukapheresis (LP) machines has been launched, measures of benchmarking and quality control need to be defined in order to ensure consistent collection performance. OBJECTIVES: The goal of this project was to establish and evaluate a benchmarking system for autologous PBSC collection. METHODS: This retrospective study evaluated PBSC collection data of 198 patients with symptomatic multiple myeloma in first-line therapy who underwent LP in 2013 and 2014 at our institution...
October 11, 2016: Transfusion Medicine
https://www.readbyqxmd.com/read/27726219/combined-cell-index-in-assessing-blood-donor-iron-stores
#7
T Vuk, J Bingulac-Popović, T Očić, L J Mayer, M Milošević, I Jukić
OBJECTIVES: The aim of this study was to assess the appropriateness of using combined cell index (CCI) in the assessment of iron stores in blood donors. This index is calculated by the formula: red blood cell distribution width (RDW) × 10(4) × mean corpuscular volume (MCV)(-1) × mean corpuscular haemoglobin (MCH)(-1) . BACKGROUND: Ferritin measurement is a reliable method for estimating iron stores in blood donors. The sensitivity of red blood cell (RBC) parameters of complete blood count in detecting non-anaemic iron deficiency is significantly lower...
October 11, 2016: Transfusion Medicine
https://www.readbyqxmd.com/read/27726216/implementation-of-a-transfusion-bundle-reduces-inappropriate-red-blood-cell-transfusions-in-intensive-care-a-before-and-after-study
#8
M Borgert, J Binnekade, F Paulus, M Vroom, A Vlaar, A Goossens, D Dongelmans
BACKGROUND: Restrictive red blood cell (RBC) transfusion has been widely described in transfusion guidelines. However, compliance with these guidelines is often poor. Therefore, we developed a care bundle for the transfusion of RBCs in intensive care. We investigated the effect of the application of the transfusion bundle on transfusion practice, hypothesising that the implementation of the transfusion bundle would lead to a reduction of inappropriate RBC transfusions. STUDY DESIGN AND METHODS: We conducted a before and after study between January and December 2014 in a medical-surgical intensive care unit (ICU) of a university hospital in Amsterdam, the Netherlands...
October 11, 2016: Transfusion Medicine
https://www.readbyqxmd.com/read/27723157/improving-the-screening-of-blood-donors-with-syphilis-rapid-diagnostic-test-rdt-and-rapid-plasma-reagin-rpr-in-low-and-middle-income-countries-lmic
#9
F Sarkodie, O Hassall, E Owusu-Dabo, S Owusu-Ofori, I Bates, I C Bygbjerg, A Owusu-Ofori, L H Harritshøj, H Ullum
BACKGROUND: Syphilis testing conventionally relies on a combination of non-treponemal and treponemal tests. The primary objective of this study was to describe the positive predictive value (PPV) of a screening algorithm in a combination of a treponemal rapid diagnostic test (RDT) and rapid plasma reagin (RPR) test at Komfo Anokye Teaching Hospital (KATH), Ghana. MATERIALS AND METHODS: From February 2014 to January 2015, 5 mL of venous blood samples were taken from 16 016 blood donors and tested with a treponemal RDT; 5 mL of venous blood was taken from 526 consenting initial syphilis sero-reactive blood donors...
October 10, 2016: Transfusion Medicine
https://www.readbyqxmd.com/read/27714885/knowledge-and-attitudes-among-pregnant-women-and-maternity-staff-about-umbilical-cord-blood-banking
#10
R Matijević, K Erjavec
No abstract text is available yet for this article.
October 7, 2016: Transfusion Medicine
https://www.readbyqxmd.com/read/27714882/a-case-of-anaphylactic-like-reaction-during-ldl-apheresis-a-pathophysiological-hypothesis-on-white-wine-containing-metabisulphite
#11
F Sbrana, G Cardinali, B Dal Pino, F Bigazzi, L Sabatino, M Pianelli, R Luciani, T Sampietro
No abstract text is available yet for this article.
October 7, 2016: Transfusion Medicine
https://www.readbyqxmd.com/read/27714877/reversal-of-warfarin-anticoagulation-using-prothrombin-complex-concentrate-at-25-iu-kg-1-results-of-the-rapid-study
#12
N Appleby, E Groarke, M Crowley, F A Wahab, A M McCann, L Egan, D Gough, G McMahon, D O'Donghaile, D O'Keeffe, N O'Connell
BACKGROUND: Real-world studies of the emergency reversal of warfarin using 4-factor prothrombin complex concentrate (PCC) report unwarranted delays. The delay to receiving PCC was ≥ 8 h in 46·7% of patients with warfarin-associated bleeding (PWAB) treated with a variable PCC dosing protocol in our retrospective audit. OBJECTIVE: To report the impact of a simplified PCC dosing protocol on the interval to reversal of anticoagulation. METHODS: We developed a PCC dosing protocol standardising the initial PCC dose and simplifying dosing calculations...
October 7, 2016: Transfusion Medicine
https://www.readbyqxmd.com/read/27696677/human-platelet-antigens-in-burmese-karen-and-north-eastern-thais
#13
R Phuangtham, A Romphruk, C Puapairoj, C Leelayuwat, A V Romphruk
OBJECTIVES: A comparative study of allele frequencies at HPA-1 to -6 and HPA-15 in Burmese and Karen populations as well as at HPA-15 in north-eastern Thais (NET) is presented. BACKGROUND: Human platelet antigens (HPAs) are clinically important in several immune platelet disorders, including foetal and neonatal alloimmune thrombocytopenia (FNAIT), post-transfusion purpura (PTP) and platelet transfusion refractoriness (PTR). The knowledge of antigen frequencies in a population is essential for the evaluation of patients suffering from immune-mediated platelet disorders...
October 3, 2016: Transfusion Medicine
https://www.readbyqxmd.com/read/27666754/obstetrical-transfusion-medicine-knowledge-among-faculty-and-trainee-obstetricians-a-prospective-knowledge-assessment-study
#14
S Morris, M H Yudin, J Callum, A Alam, J Herold, Y Lin
OBJECTIVES: To evaluate the current state of transfusion medicine (TM) knowledge among obstetricians using a valid assessment tool. BACKGROUND: Transfusion issues are common in obstetrical patients. METHODS: Knowledge topics were identified and rated by experts in obstetrics, anaesthesia, haematology and TM using a modified Delphi method. A knowledge assessment tool was developed and validated during pilot testing. The assessment tool, consisting of 15 multiple choice questions, was administered electronically to members of the Society of Obstetricians and Gynaecologists of Canada (SOGC)...
September 26, 2016: Transfusion Medicine
https://www.readbyqxmd.com/read/27653186/the-accuracy-of-claims-data-for-measuring-transfusion-rates
#15
D H Howard, A Karcz, J D Roback
OBJECTIVE: To determine if billing records accurately report the receipt of red blood cell transfusions. BACKGROUND: Many red blood transfusions are given inappropriately, but efforts to monitor transfusion rates are hampered by a lack of data that facilitate benchmarking. METHODS: Using billing records and electronic medical records from 53 community hospitals, we estimated the sensitivity and specificity of billing records for measuring the receipt of transfusions in patients undergoing surgery for hip fractures...
September 22, 2016: Transfusion Medicine
https://www.readbyqxmd.com/read/27634655/knowledge-attitudes-and-practices-towards-blood-donation-in-barbados
#16
A E Atherley, C G Taylor, A Whittington, C Jonker
OBJECTIVE: To obtain information to devise strategies for a voluntary blood donor mobilisation campaign in Barbados. BACKGROUND: The World Health Organisation (WHO) recommends that 100% blood should be collected from voluntary non-remunerated donors (VNRD), yet the majority of blood donations (75%) in Barbados are family/replacement donations. Increasing VNRD is paramount to achieving a safe, reliable blood supply, and understanding the population is a strategy suggested by the WHO to inform donor recruitment and education...
September 16, 2016: Transfusion Medicine
https://www.readbyqxmd.com/read/27634577/selection-of-gp-mur-antigen-negative-rbc-for-blood-recipients-with-anti-mi-a-records-decreases-transfusion-reaction-rates-in-taiwan
#17
C-A Yang, J-A Lin, C-W Chang, K-H Wu, S-P Yeh, C-M Ho, J-G Chang
OBJECTIVES: To evaluate the clinical significance of GP. Mur antigen-negative blood selection for transfusion in patients with anti-'Mi(a) ' records. BACKGROUND: The GP. Mur RBC phenotype is prevalent (7·3%) in Taiwan. Antibodies against GP. Mur (anti-'Mi(a) ') are identified in 1·24% of our population, and anti-'Mi(a) ' screening using GP. Mur RBC has been routine for Taiwan's blood banks. However, due to the lack of commercial antibodies, only cross-matching was used to prevent transfusion of GP...
September 15, 2016: Transfusion Medicine
https://www.readbyqxmd.com/read/27535575/platelet-function-testing-in-cardiac-surgery
#18
S Agarwal
Bleeding in cardiac surgery is known to cause increased morbidity and mortality. The rise in the use of anti-platelet medication has led to an increase in the number of patients presenting for cardiac surgery with platelet dysfunction, who are at a heightened risk of bleeding. However, the extent of platelet inhibition is well known to differ among individuals. In the past few years, a number of point-of-care platelet function testing devices, which may be able to assess platelet reactivity, have entered the market...
October 2016: Transfusion Medicine
https://www.readbyqxmd.com/read/27641446/abstracts-of-the-annual-scientific-meeting-of-the-british-blood-transfusion-society-21-23-september-2016-harrogate-international-centre-north-yorkshire-uk
#19
(no author information available yet)
No abstract text is available yet for this article.
September 2016: Transfusion Medicine
https://www.readbyqxmd.com/read/27569439/blood-transfusion-for-patients-with-newly-diagnosed-acute-myeloid-leukaemia-undergoing-induction-chemotherapy-in-a-large-medical-centre-in-china-a-retrospective-analysis
#20
B Han, C Chen, L Wang, B Tan, C Huang, L Qin, H Zhu
No abstract text is available yet for this article.
August 28, 2016: Transfusion Medicine
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