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Transfusion Medicine

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https://www.readbyqxmd.com/read/28547759/blood-donors-attitudes-towards-voluntary-non-remunerated-donation-in-trinidad-and-tobago
#1
K S Charles, A Poon King, A Ramai, K Rajnath, D Ramkissoon, S Ramkissoon, C Ramlal, K Ramnarine, K Rampersad, G Legall, S Pooransingh, A D Chantry
OBJECTIVES: To assess the attitude towards voluntary non-remunerated blood donation among blood donors in Trinidad and Tobago (TRT). BACKGROUND: Blood donors in TRT are either family replacement (F/R, 87%) or remunerated (13%). There is chronic blood shortage and high seroreactivity for transfusion-transmissible infections (TTI) in donors. Converting existing to voluntary non-remunerated donors (VNRD) reduces the need to recruit news donors in achieving 100% VNRD...
May 26, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28543884/psychological-factors-related-to-donation-behaviour-among-chinese-adults-results-from-a-longitudinal-investigation
#2
H Hu, T Wang, Q Fu
BACKGROUND AND OBJECTIVES: Little is known about the psychological factors currently influencing blood donation in China. This study investigated the structure of psychological factors and their correlation with donation behaviour of adults in a transforming city in China over a 6-month period. METHODS: Participants were recruited in Nanjing from May 2013 to April 2014. Preliminary focus group interviews with 102 participants were conducted to generate new items for a Theory of Planned Behaviour (TPB) questionnaire...
May 22, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28524626/cardiac-arrest-triggered-by-hyperkalemia-during-red-blood-cell-transfusion-a-case-report-and-literature-review
#3
LETTER
Z Zhang, Y Shen, B Li, N Li
No abstract text is available yet for this article.
May 19, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28524621/a-fatal-case-of-autoanti-wr-b-causing-autoagglutination-of-red-blood-cells-and-intravascular-haemolysis
#4
LETTER
K Maguire, K Morris, M Quinn, B Herron, A Rainey, N Thornton
No abstract text is available yet for this article.
May 19, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28524547/performance-of-a-new-generation-continuous-autotransfusion-device-including-fat-removal-and-consequences-for-quality-controls
#5
T F Seyfried, M Gruber, D Bitzinger, M T Pawlik, A Breu, B M Graf, E Hansen
BACKGROUND AND OBJECTIVES: Cell salvage plays a key role in blood conservation. To maintain high performance, quality management is recommended. Accordingly, a new-generation autotransfusion device was tested for its performance and compared with its predecessor. Two different calculations of quality parameters were applied. MATERIALS AND METHODS: In an experimental study, the continuous autotransfusion devices CATSmart and Continuous Autotransfusion System (C.A...
May 19, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28524366/contrasting-hcv-and-hiv-seroepidemiology-in-11-years-of-blood-donors-screening-in-brazil
#6
J E Levi, S M Lira, C B Bub, M B Polite, C C Terzian, J M Kutner
BACKGROUND: Blood donors are, in principle, healthy individuals who may be revealed as infectious for blood-borne agents by the laboratory screening process, depicting the asymptomatic burden of the disease. Therefore, monitoring hepatitis C virus (HCV)-infected donor and human immunodeficiency virus (HIV)-infected donor and associating to their demographical and behavioural characteristics may shed light on the dynamics and contemporary changes in these viruses' epidemiology. METHODS: Donors presenting repeatedly reactive HCV or HIV serology/nucleic acid testing (NAT) screening results were submitted to confirmatory testing...
May 19, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28516675/analysis-of-platelet-reactive-alloantibodies-and-evaluation-of-cross-match-compatible-platelets-for-the-management-of-patients-with-transfusion-refractoriness
#7
J Wang, W Xia, J Deng, X Xu, Y Shao, H Ding, Y Chen, J Liu, D Chen, X Ye, S Santoso
BACKGROUND: Cross-match-compatible platelets can improve corrected count increments (CCIs) in alloimmunised patients with transfusion refractoriness. However, only a few studies mentioned that the specificities of platelet-reactive alloantibodies can predict high reactivity in cross-match assays among these patients. METHODS: A total of 204 medical records of patients who were refractory to random single-donor apheresis platelets between January 2014 and December 2014 were enrolled...
May 18, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28516464/the-blood-donation-ambivalence-survey-measuring-conflicting-attitudes-about-giving-blood
#8
K R Fox, L K Himawan, C R France
OBJECTIVES: This study was designed to develop and conduct initial validation testing for a novel measure of ambivalence about donating blood. BACKGROUND: Previous studies of living organ, bone marrow and stem cell donors have identified donation-related ambivalence as a predictor of decisions about donation and post-donation outcomes. Ambivalence about blood donation has not received the same attention. METHODS: In Study 1, a sample of young adults (N = 396) were administered test items of ambivalence, and exploratory (EFA) and confirmatory factor analyses (CFA) were performed to identify the Blood Donation Ambivalence Survey...
May 18, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28508562/can-serological-methods-help-distinguish-between-prophylactic-and-alloimmune-anti-d
#9
C Irving, M Crennan, T Vanniasinkam
OBJECTIVES: Enzyme indirect antiglobulin test (EIAT) and polyethylene glycol IAT (PIAT) were evaluated for their potential use as tests to distinguish between prophylactic and alloimmune anti-D in plasma by comparing with a tube variation of the standard low ionic strength solution-IAT (LISS-IAT). BACKGROUND: Laboratories performing the screening of RhD-negative pregnant women are required to provide clinicians with guidance as to the source of detected RhD antibodies...
May 15, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28470880/virus-inactivation-by-25-kgy-gamma-irradiation-during-a-new-manufacturing-process-of-%C3%AE-2-macroglobulin
#10
LETTER
C Huangfu, Y Ma, J Jia, M Lv, F Zhu, X Ma, X Zhao, J Zhang
No abstract text is available yet for this article.
May 4, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28425182/serum-ferritin-thresholds-for-the-diagnosis-of-iron-deficiency-in-pregnancy-a-systematic-review
#11
REVIEW
J Daru, J Allotey, J P Peña-Rosas, K S Khan
The aim of this review was to understand the landscape of serum ferritin in diagnosing iron deficiency in the aetiology of anaemia in pregnancy. Iron deficiency in pregnancy is a major public health problem leading to the development of anaemia. Reducing the global prevalence of anaemia in women of reproductive age is a 2025 global nutrition target. Bone marrow aspiration is the gold standard test for iron deficiency but requires an invasive procedure; therefore, serum ferritin is the most clinically useful test...
April 20, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28419585/a-new-discrepancy-of-hpa-3-genotyping-because-of-a-rare-hpa-27bw-polymorphism
#12
LETTER
G Bertrand, A Aarnink, C Nivet, A Jacques, M Cherel, V Renac, A Kennel
No abstract text is available yet for this article.
April 17, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28401678/a-and-b-antigen-levels-acquired-by-group-o-donor-derived-erythrocytes-following-abo-non-identical-transfusion-or-minor-abo-incompatible-haematopoietic-stem-cell-transplantation
#13
A K Hult, J H Dykes, J R Storry, M L Olsson
BACKGROUND AND OBJECTIVES: ABO-incompatible haematopoietic stem cell transplantation (HSCT) presents a challenge to blood component transfusion. The aim of this study was to investigate the weak blood group A or B antigen expression by donor-derived group O red blood cells (RBC) observed following transfusion or minor ABO-incompatible HSCT. In addition, in vitro experiments were performed to elucidate possible mechanisms underlying this phenomenon. MATERIALS AND METHODS: A sensitive flow cytometry assay for the semi-quantification of RBC A/B antigen levels was used to assess patient samples and evaluate in vitro experiments...
April 12, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28401611/pegylated-bovine-carboxyhaemoglobin-utilisation-in-a-thrombotic-thrombocytopenic-purpura-patient
#14
C Sam, P Desai, D Laber, A Patel, N Visweshwar, M Jaglal
OBJECTIVE: To determine if pegylated bovine carboxyhaemoglobin can be utilised in a thrombotic thrombocytopenic purpura (TTP) patient. BACKGROUND: TTP is a condition characterized by thrombotic microangiopathy and has a high mortality rate when left untreated. Therapeutic plasma exchange is well established as the most effective and evidence-based treatment of TTP. METHODS: The ability to administer plasma exchange therapy is limited in Jehovah's Witnesses who decline blood products due to religious beliefs...
April 12, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28393455/hlamatchmaker-is-effective-for-selecting-appropriate-platelet-units-for-alloimmunised-thrombocytopaenic-patients-who-are-refractory-to-random-donor-platelets
#15
C O'Rafferty, G Rooney, R Hagan, M Woolfson, D O'Donghaile, J Fitzgerald
BACKGROUND: HLAMatchmaker has been used in the Irish Blood Transfusion Service (IBTS) to select platelets for HLA-alloimmunised, platelet refractory thrombocytopaenic patients since 2006. Although available since 2002, only three studies have been published supporting the programme's effectiveness for this indication. OBJECTIVES: We sought to examine increments to HLA-matched platelets (HMPs) at various matchmaker scores and to examine the impact of transfusing older platelets and ABO-mismatched platelets to this patient group...
April 10, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28382765/factors-influencing-blood-donation-a-cross-sectional-survey-in-guangzhou-china
#16
J Ou-Yang, C-H Bei, B He, X Rong
OBJECTIVES: The present study aimed to determine major factors that influence blood donation in China. BACKGROUND: Factors affecting blood donation often vary in various populations. METHODS: This cross-sectional study used self-administered, standardised, structured questionnaires to survey selected donors and non-donors in Guangzhou, China between 10 December 2013 and 25 June 2014. RESULTS: Among the 1080 questionnaires collected, 1034 (95·7%) questionnaires were valid for this analysis, including 602 donors and 432 non-donors...
April 6, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28382715/platelet-donor-selection-for-hla-immunised-patients-the-impact-of-donor-specific-hla-antibody-levels
#17
T Linjama, R Niittyvuopio, J Tuimala, M Pyörälä, H Rintala, J Rimpiläinen, M Kauppila, J Peräsaari, E Juvonen
BACKGROUND: Approximately 20% of patients with a recurrently poor platelet transfusion increment show human leukocyte antigen (HLA) alloantibodies. The aim of this study was to analyse the impact of mean fluorescence intensity (MFI) levels of donor-specific HLA antibodies and the feasibility of the HLAMatchmaker algorithm in donor selection. STUDY DESIGN AND METHODS: A total of 270 HLA-typed platelet transfusion responses of 40 patients were included in the study...
April 6, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28370709/where-does-the-albumin-go-human-albumin-solution-usage-following-the-implementation-of-a-demand-management-programme
#18
M S Yazdani, A Retter, T Maggs, P Li, M G Robson, C Reid, P Holmes, T Garood, S E Robinson
OBJECTIVE: To outline the Guy's and St Thomas' NHS Foundation Trust (GSTFT) and Evelina London Children's Hospital (ELCH) demand management plan for human albumin solution (HAS) and usage. BACKGROUND: There is no UK-wide guidance governing the use of HAS. A severe shortage in 2015 prompted a Trust demand management programme. Indications were categorised according to locally agreed colour code and ASFA categories. METHODS: Following the implementation of the demand management programme, a 6-month audit of HAS usage was completed...
April 3, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28295765/a-nationwide-survey-on-out-of-hospital-transfusions-in-the-netherlands
#19
LETTER
A J van Gammeren, M M C Haneveer
No abstract text is available yet for this article.
March 12, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28295747/the-impact-of-providing-blood-to-the-scene-of-an-accident-on-transfusion-laboratory-practice
#20
S Wolf, J Morris, K Kennedy, M Lawn, T Mcloughlin, K Feane, J Uprichard, A Weaver, S Allard, L Green
BACKGROUND: Haemorrhage is the leading cause of mortality during trauma. In 2012, London's Air Ambulance introduced Blood on Board (BOB), transfusing group O red cells (RBC) to trauma patients at the scene. OBJECTIVES: This study assessed the impact of BOB on the number of mixed field samples received by the laboratory, the number of group O RBC transfused to non-group O patients and the ratio of RBC to fresh frozen plasma (FFP) transfused in the initial 24 h. METHODS: Three major trauma centres collected data on patients for whom the major haemorrhage protocol was activated between August 2008 and February 2012 pre-BOB and March 2012 and December 2013 post-BOB...
March 12, 2017: Transfusion Medicine
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