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Transfusion Medicine

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https://www.readbyqxmd.com/read/28425182/serum-ferritin-thresholds-for-the-diagnosis-of-iron-deficiency-in-pregnancy-a-systematic-review
#1
REVIEW
J Daru, J Allotey, J P Peña-Rosas, K S Khan
The aim of this review was to understand the landscape of serum ferritin in diagnosing iron deficiency in the aetiology of anaemia in pregnancy. Iron deficiency in pregnancy is a major public health problem leading to the development of anaemia. Reducing the global prevalence of anaemia in women of reproductive age is a 2025 global nutrition target. Bone marrow aspiration is the gold standard test for iron deficiency but requires an invasive procedure; therefore, serum ferritin is the most clinically useful test...
April 20, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28419585/a-new-discrepancy-of-hpa-3-genotyping-because-of-a-rare-hpa-27bw-polymorphism
#2
LETTER
G Bertrand, A Aarnink, C Nivet, A Jacques, M Cherel, V Renac, A Kennel
No abstract text is available yet for this article.
April 17, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28401678/a-and-b-antigen-levels-acquired-by-group-o-donor-derived-erythrocytes-following-abo-non-identical-transfusion-or-minor-abo-incompatible-haematopoietic-stem-cell-transplantation
#3
A K Hult, J H Dykes, J R Storry, M L Olsson
BACKGROUND AND OBJECTIVES: ABO-incompatible haematopoietic stem cell transplantation (HSCT) presents a challenge to blood component transfusion. The aim of this study was to investigate the weak blood group A or B antigen expression by donor-derived group O red blood cells (RBC) observed following transfusion or minor ABO-incompatible HSCT. In addition, in vitro experiments were performed to elucidate possible mechanisms underlying this phenomenon. MATERIALS AND METHODS: A sensitive flow cytometry assay for the semi-quantification of RBC A/B antigen levels was used to assess patient samples and evaluate in vitro experiments...
April 12, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28401611/pegylated-bovine-carboxyhaemoglobin-utilisation-in-a-thrombotic-thrombocytopenic-purpura-patient
#4
C Sam, P Desai, D Laber, A Patel, N Visweshwar, M Jaglal
OBJECTIVE: To determine if pegylated bovine carboxyhaemoglobin can be utilised in a thrombotic thrombocytopenic purpura (TTP) patient. BACKGROUND: TTP is a condition characterized by thrombotic microangiopathy and has a high mortality rate when left untreated. Therapeutic plasma exchange is well established as the most effective and evidence-based treatment of TTP. METHODS: The ability to administer plasma exchange therapy is limited in Jehovah's Witnesses who decline blood products due to religious beliefs...
April 12, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28393455/hlamatchmaker-is-effective-for-selecting-appropriate-platelet-units-for-alloimmunised-thrombocytopaenic-patients-who-are-refractory-to-random-donor-platelets
#5
C O'Rafferty, G Rooney, R Hagan, M Woolfson, D O'Donghaile, J Fitzgerald
BACKGROUND: HLAMatchmaker has been used in the Irish Blood Transfusion Service (IBTS) to select platelets for HLA-alloimmunised, platelet refractory thrombocytopaenic patients since 2006. Although available since 2002, only three studies have been published supporting the programme's effectiveness for this indication. OBJECTIVES: We sought to examine increments to HLA-matched platelets (HMPs) at various matchmaker scores and to examine the impact of transfusing older platelets and ABO-mismatched platelets to this patient group...
April 10, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28382765/factors-influencing-blood-donation-a-cross-sectional-survey-in-guangzhou-china
#6
J Ou-Yang, C-H Bei, B He, X Rong
OBJECTIVES: The present study aimed to determine major factors that influence blood donation in China. BACKGROUND: Factors affecting blood donation often vary in various populations. METHODS: This cross-sectional study used self-administered, standardised, structured questionnaires to survey selected donors and non-donors in Guangzhou, China between 10 December 2013 and 25 June 2014. RESULTS: Among the 1080 questionnaires collected, 1034 (95·7%) questionnaires were valid for this analysis, including 602 donors and 432 non-donors...
April 6, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28382715/platelet-donor-selection-for-hla-immunised-patients-the-impact-of-donor-specific-hla-antibody-levels
#7
T Linjama, R Niittyvuopio, J Tuimala, M Pyörälä, H Rintala, J Rimpiläinen, M Kauppila, J Peräsaari, E Juvonen
BACKGROUND: Approximately 20% of patients with a recurrently poor platelet transfusion increment show human leukocyte antigen (HLA) alloantibodies. The aim of this study was to analyse the impact of mean fluorescence intensity (MFI) levels of donor-specific HLA antibodies and the feasibility of the HLAMatchmaker algorithm in donor selection. STUDY DESIGN AND METHODS: A total of 270 HLA-typed platelet transfusion responses of 40 patients were included in the study...
April 6, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28370709/where-does-the-albumin-go-human-albumin-solution-usage-following-the-implementation-of-a-demand-management-programme
#8
M S Yazdani, A Retter, T Maggs, P Li, M G Robson, C Reid, P Holmes, T Garood, S E Robinson
OBJECTIVE: To outline the Guy's and St Thomas' NHS Foundation Trust (GSTFT) and Evelina London Children's Hospital (ELCH) demand management plan for human albumin solution (HAS) and usage. BACKGROUND: There is no UK-wide guidance governing the use of HAS. A severe shortage in 2015 prompted a Trust demand management programme. Indications were categorised according to locally agreed colour code and ASFA categories. METHODS: Following the implementation of the demand management programme, a 6-month audit of HAS usage was completed...
April 3, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28295765/a-nationwide-survey-on-out-of-hospital-transfusions-in-the-netherlands
#9
LETTER
A J van Gammeren, M M C Haneveer
No abstract text is available yet for this article.
March 12, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28295747/the-impact-of-providing-blood-to-the-scene-of-an-accident-on-transfusion-laboratory-practice
#10
S Wolf, J Morris, K Kennedy, M Lawn, T Mcloughlin, K Feane, J Uprichard, A Weaver, S Allard, L Green
BACKGROUND: Haemorrhage is the leading cause of mortality during trauma. In 2012, London's Air Ambulance introduced Blood on Board (BOB), transfusing group O red cells (RBC) to trauma patients at the scene. OBJECTIVES: This study assessed the impact of BOB on the number of mixed field samples received by the laboratory, the number of group O RBC transfused to non-group O patients and the ratio of RBC to fresh frozen plasma (FFP) transfused in the initial 24 h. METHODS: Three major trauma centres collected data on patients for whom the major haemorrhage protocol was activated between August 2008 and February 2012 pre-BOB and March 2012 and December 2013 post-BOB...
March 12, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28271567/the-welsh-blood-service-70-years-of-continuous-change
#11
REVIEW
G D Poole
The National Blood Transfusion Service (NBTS) in England and Wales was established as a single entity in 1946 and operated as such for almost half a century. During those 50 years, the blood service in Wales, as in the rest of the UK, saw many technological and operational changes. The automation of donation testing, the introduction of successive layers of microbiological screening, the creation of the Tissue Typing Laboratory (later renamed the Welsh Transplantation and Immunogenetics Laboratory) and the development of information technology brought - over a relatively long period - highly significant improvements to an organisation that had begun life as an Emergency Medical Service...
March 8, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28251708/autotransfusion-for-a-haemothorax-complicating-an-echis-pyramidum-envenomation-in-republic-of-djibouti
#12
LETTER
F-X Jean, S Larréché, F Petitjeans, M Puidupin, G Mion
No abstract text is available yet for this article.
March 2, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28251700/prevalence-of-maternal-alloantibodies-in-a-large-teaching-hospital-and-their-impact-on-outcomes-of-fetuses-neonates
#13
LETTER
L Ainley, J R Jardim, J Tan, S Beski, E M RiosLeal, S Allard, L Green
No abstract text is available yet for this article.
March 2, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28233935/blood-donors-awareness-and-attitudes-towards-blood-transfusion-safety-in-the-autonomous-province-of-vojvodina-serbia
#14
S Bogdanović, P Đurić, R Jovanović, J Bogdanović
OBJECTIVES: To assess the awareness and attitudes related to blood transfusion safety among blood donors from the Autonomous Province (AP) Vojvodina, Republic of Serbia. BACKGROUND: Blood donors are at the initial point of safe blood transfusion systems. The active participation of blood donors in the selection process contributes to increasing the safety of blood transfusions and reduces potential risks for the recipients. MATERIALS AND METHODS: This cross-sectional survey included 1191 blood donors from AP Vojvodina...
February 24, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28233920/a-rare-cause-of-blood-clots-in-blood-bag
#15
LETTER
N Bejarano, J Macías, C Sanz, A Pereira
No abstract text is available yet for this article.
February 24, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28230309/evaluation-of-positive-and-false-positive-results-in-syphilis-screening-of-blood-donors-in-rio-de-janeiro-brazil
#16
V S Sandes, S G C Silva, I J F Motta, L G C Velarde, S R de Castilho
OBJECTIVES: We propose to analyse the positive and false-positive results of treponemal and nontreponemal tests in blood donors from Brazil and to evaluate possible factors associated with the results of treponemal tests. BACKGROUND: Treponemal tests have been used widely for syphilis screening in blood banks. The introduction of these tests in donor screening has caused an impact and a loss of donors who need to be assessed. METHODS: This was a retrospective cross-sectional study of syphilis screening and confirmatory test results of blood donors that were obtained before and after adopting a chemiluminescent immunoassay (CLIA)...
February 23, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28230298/vitamin-e-nanoemulsion-activity-on-stored-red-blood-cells
#17
C A L Silva, C A Azevedo Filho, G Pereira, D C N Silva, M C A B Castro, A F Almeida, S C A Lucena, B S Santos, M L Barjas-Castro, A Fontes
BACKGROUND: Stored red blood cells (RBCs) undergo numerous changes that have been termed RBC storage lesion, which can be related to oxidative damage. Vitamin E is an important antioxidant, acting on cell lipids. Thus, this study aimed to investigate vitamin E activity on stored RBCs. METHODS: We prepared a vitamin E nanoemulsion that was added to RBC units and stored at 4 °C. Controls, without vitamin E, were kept under the same conditions. Reactive oxygen species (ROS) production was monitored for up to 35 days of storage...
February 23, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28168861/autologous-peripheral-blood-stem-cell-harvest-and-transplant-in-a-patient-with-cold-agglutinin-disease-secondary-to-lymphoma
#18
LETTER
K G Badami, M P Smith, D Murton, S Rodger, G Atkinson
No abstract text is available yet for this article.
February 7, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28144996/audit-of-provincial-ivig-request-forms-and-efficacy-documentation-in-four-ontario-tertiary-care-centres
#19
A W Shih, E Jamula, C Diep, Y Lin, C Armali, N M Heddle, A Traore, J Doherty, N Shah, C M Hillis
OBJECTIVE: Retrospective audit of IVIG Request Forms in four Ontario tertiary care centres: to determine the case mix of new IVIG requests, to authenticate information provided, and to determine documentation of clinical efficacy. AIMS: To understand contributors to increases in IVIG utilisation and to determine whether IVIG is being used and monitored appropriately. INTRODUCTION: Intravenous immunoglobulin (IVIG) use in Canada is high compared with other developed countries...
January 31, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28139022/detection-of-adverse-events-of-transfusion-in-a-teaching-hospital-in-ghana
#20
A K Owusu-Ofori, S P Owusu-Ofori, I Bates
BACKGROUND AND OBJECTIVES: Monitoring the whole chain of events from the blood donors to recipients, documenting any undesirable or untoward effects and introducing measures to prevent their recurrence if possible are components of haemovigilance systems. Only few sub-Saharan African countries have haemovigilance systems, and there are very little data on adverse events of transfusion. Adverse events monitoring is an integral part of a haemovigilance system. Our study aimed to establish the incidence and types of adverse events of transfusions in Ghana and to identify interventions to improve effectiveness...
January 31, 2017: Transfusion Medicine
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