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Journal of Glaucoma

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https://www.readbyqxmd.com/read/28169924/retrograde-maculopathy-in-patients-with-glaucoma
#1
Jacqueline Brazerol, Milko E Iliev, René Höhn, Stephan Fränkl, Hilary Grabe, Mathias Abegg
PURPOSE: Macular optical coherence tomography (OCT) analysis can be used for quantitative measures of optic nerve atrophy at a location far from the optic nerve head. This recently led to the finding of microcystic macular edema (MME), that is vacuolar inclusions in the macular inner nuclear layer, in some glaucoma patients. The involvement of individual retinal layers is yet unclear in glaucoma. In this study we systematically investigated glaucoma-induced changes in macular layers to evaluate whether glaucoma-associated damage extends beyond the macular ganglion cell layer...
February 6, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28169923/analysis-of-fellow-eye-intraocular-pressure-changes-after-glaucoma-surgery-in-1-eye
#2
Sushmita Kaushik, Aniruddha Agarwal, Savleen Kaur, Neiwete Lomi, Srishti Raj, Surinder Singh Pandav
No abstract text is available yet for this article.
February 6, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28169922/choroidal-vessel-diameters-in-pseudoexfoliation-and-pseudoexfoliation-glaucoma-analyzed-using-spectral-domain-optical-coherence-tomography
#3
Soshian Sarrafpour, Mehreen Adhi, Jason Y Zhang, Jay S Duker, Chandrasekharan Krishnan
PURPOSE OF THE STUDY: The purpose of the study was to analyze choroidal vessel diameters in pseudoexfoliation (PXF) and pseudoexfoliation glaucoma (PXFG) using spectral-domain optical coherence tomography (SD-OCT). MATERIALS AND METHODS: Fifty patients (100 eyes) with PXF and PXFG who underwent high-definition 1-line raster SD-OCT imaging at New England Eye Center, Boston, were retrospectively identified and divided into unilateral PXFG (26 patients, 52 eyes), unilateral PXF (4 patients, 8 eyes), bilateral PXFG (4 patients, 8 eyes), and bilateral PXF (16 patients, 32 eyes)...
February 6, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28169921/predicting-the-magnitude-of-functional-and-structural-damage-in-glaucoma-from-monocular-pupillary-light-responses-using-automated-pupillography
#4
Zia S Pradhan, Harsha L Rao, Narendra K Puttaiah, Sujatha V Kadambi, Srilakshmi Dasari, Hemanth B Reddy, Meena Palakurthy, Mohammed Riyazuddin, Dhanaraj A S Rao
PURPOSE: To predict the magnitude of functional damage [mean deviation (MD) on visual field examination] and structural damage [retinal nerve fiber layer (RNFL) and ganglion cell complex (GCC) thickness on spectral domain optical coherence tomography] in glaucoma from monocular pupillary light response measurements using automated pupillography. METHODS: In total, 59 subjects (118 eyes) with either a confirmed or suspected diagnosis of glaucoma underwent automated pupillography, along with visual fields and spectral domain optical coherence tomography examinations...
February 6, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28169920/relationship-between-oct-angiography-temporal-peripapillary-vessel-density-and-octopus-perimeter-paracentral-cluster-mean-defect
#5
Gábor Holló
PURPOSE OF THE STUDY: The purpose of the study was to investigate the relationship between optical coherence tomography angiography angioflow vessel-density (PAFD) measured in the retinal nerve fiber layer in the temporal peripapillary sector and the average of the spatially corresponding superior and inferior paracentral cluster mean defect values (mean paracentral MD) measured with Octopus perimetry. MATERIALS AND METHODS: Spaerman's correlation between temporal peripapillary PAFD acquired with the Angiovue OCT and mean paracentral MD measured with the Normal and tendency-oriented perimetry strategy of Octopus G2 perimetry, respectively, was determined on 1 eye of 13 healthy participants, 22 medically controlled ocular hypertensive, and 27 stable early to moderate glaucoma patients...
February 6, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28169919/caution-in-using-the-xen-augmented-baerveldt-surgical-technique
#6
Elisa D'Alessandro, Jacopo M Guidotti, Kaweh Mansouri, André Mermoud
No abstract text is available yet for this article.
February 6, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28169918/bilateral-blebs-secondary-to-spontaneous-scleral-perforations
#7
Ester Fernández López, Alexander Poon, Andrew Huhtanen, Richard Lindsay, Catherine Green
PURPOSE: To report an unusual case of bilateral spontaneous scleral perforations. METHODS: A 34-year-old woman presented with bilateral conjunctival blebs and decreased vision in both eyes. There was no history of ocular trauma or surgery and no previous ophthalmic or systemic conditions that may have contributed to the scleral perforations. RESULTS: Best-corrected visual acuity was 20/40 in both eyes and intraocular pressures were 6 mm Hg in the right and 5 mm Hg in the left...
February 6, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28169917/targeting-transforming-growth-factor-%C3%AE-signaling-in-primary-open-angle-glaucoma
#8
Jenny Wang, Alon Harris, Mark A Prendes, Loor Alshawa, Josh C Gross, Scott M Wentz, Ambika B Rao, Nathaniel J Kim, Alexander Synder, Brent Siesky
Transforming growth factor-β (TGF-β) may play a role in the pathogenesis of primary open-angle glaucoma (POAG). Elevated levels of TGF-β are found in the aqueous humor and in reactive optic nerve astrocytes in patients with glaucoma. In POAG, aqueous humor outflow resistance at the trabecular meshwork (TM) leads to increased intraocular pressure and retinal ganglion cell death. It is hypothesized that TGF-β increases outflow resistance by altering extracellular matrix homeostasis and cell contractility in the TM through interactions with other proteins and signaling molecules...
February 6, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28121717/normal-tension-glaucoma-masqueraders-detection-using-optical-coherence-tomography
#9
Debbie S Kuo, Sanjay Asrani
PURPOSE: Optical coherence tomography (OCT) has become an important tool in the diagnosis and management of glaucoma; however, there can be overlap in the OCT findings between glaucoma and other diseases. We describe the clinical examination finings and interpretation of OCT imaging that led to the diagnosis of glaucoma masqueraders in a clinical case series. MATERIALS AND METHODS: Four adult patients seen in the glaucoma clinic at the Duke Eye Center were included in a retrospective observational case series...
January 24, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28121716/are-disposable-and-standard-gonioscopy-lenses-comparable
#10
Bonny Lee, Bernard C Szirth, Robert D Fechtner, Albert S Khouri
PURPOSE: Gonioscopy is important in the evaluation and treatment of glaucoma. With increased scrutiny of acceptable sterilization processes for health care instruments, disposable gonioscopy lenses have recently been introduced. Single-time use lenses are theorized to decrease infection risk and eliminate the issue of wear and tear seen on standard, reusable lenses. However, patient care would be compromised if the quality of images produced by the disposable lens were inferior to those produced by the reusable lens...
January 24, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28121715/ocular-decompression-retinopathy-after-uncomplicated-cataract-surgery-in-a-patient-with-a-history-of-narrow-angle-glaucoma
#11
Thomas H Dohlman, Leila Rafla-Demetrious, Mrinali P Gupta
No abstract text is available yet for this article.
January 24, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28118204/can-glaucomatous-visual-field-progression-be-predicted-by-structural-and-functional-measures
#12
Wolfgang A Schrems, Laura-M Schrems-Hoesl, Christian Y Mardin, Robert Laemmer, Friedrich E Kruse, Folkert K Horn
PURPOSE: The aim of this study was to compare the predictive value of retinal nerve fiber layer thickness (RNFLT) measurements obtained by optical coherence tomography (OCT), morphometric parameters of confocal scanning laser ophthalmoscopy (CSLO), and frequency-doubling technique perimetry to predict visual field conversion of normal individuals, ocular hypertensive subjects, and early preperimetric glaucoma patients as determined by standard automated perimetry (SAP). PATIENTS AND METHODS: This longitudinal single-center study included 107 eyes of 56 controls, 164 eyes of 98 patients with ocular hypertension, and 169 eyes of 110 patients with preperimetric glaucoma...
January 23, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28118203/evaluation-of-the-efficacy-and-safety-of-the-new-susanna-glaucoma-drainage-device-in-refractory-glaucomas-short-term-results
#13
Luis G Biteli, Tiago S Prata, Carolina P B Gracitelli, Fábio N Kanadani, Flávia Villas Boas, Marcelo Hatanaka, Augusto Paranhos Junior
PURPOSE: To assess the efficacy and safety of the new Susanna glaucoma drainage device (SGDD) in patients with neovascular and refractory glaucomas. MATERIALS AND METHODS: In this prospective study, patients with neovascular glaucoma or refractory glaucomas (defined as eyes with previous trabeculectomy failure) were enrolled. All eyes had to have intraocular pressure (IOP) above 21 mm Hg despite maximum tolerated topical medication, or recent documentation of anatomic and/or functional progression...
January 23, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28107256/comment-on-magnetic-resonance-imaging-of-cyclodialysis-cleft-before-and-after-cyclopexy
#14
Julio González-Martín-Moro, Fernando Gómez-Sanz
No abstract text is available yet for this article.
January 19, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28098579/xen-gel-stent-internal-ostium-occlusion-ab-interno-revision
#15
Nuno Pinto Ferreira, Luis Abegão Pinto, Carlos Marques-Neves
Minimally invasive glaucoma surgery aims to provide a safer and less-invasive means of reducing IOP compared with traditional surgery, with the goal of reducing the need for topical medications. The XEN gel stent is an ab-interno minimally invasive glaucoma surgery device that approaches intraocular pressure reduction by creating a subconjunctival drainage pathway. As with any new device there is lack of experience and knowledge about its long-term results in terms of efficacy, technique, and complications...
January 16, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28079658/normal-tension-glaucoma-and-low-cerebrospinal-fluid-pressure
#16
Imran H Yusuf, Gokularaj Ratnarajan, Richard S Kerr, John F Salmon
No abstract text is available yet for this article.
January 10, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28079657/diagnostic-capability-of-peripapillary-retinal-volume-measurements-in-glaucoma
#17
Huseyin Simavli, Linda Yi-Chieh Poon, Christian J Que, Yingna Liu, Mustafa Akduman, Edem Tsikata, Johannes F de Boer, Teresa C Chen
PURPOSE: To determine the diagnostic capability of spectral domain optical coherence tomography peripapillary retinal volume (RV) measurements. MATERIALS AND METHODS: A total of 156 patients, 89 primary open-angle glaucoma and 67 normal subjects, were recruited. Spectral domain optical coherence tomography peripapillary RV was calculated for 4 quadrants using 3 annuli of varying scan circle diameters: outer circumpapillary annuli of circular grids 1, 2, and 3 (OCA1, OCA2, OCA3)...
January 10, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28079656/endoscopic-cyclophotocoagulation-for-the-treatment-of-glaucoma-in-boston-keratoprosthesis-type-ii-patient
#18
Linda Yi-Chieh Poon, James Chodosh, Demetrios G Vavvas, Claes H Dohlman, Teresa C Chen
We describe the surgical technique of endoscopic cyclophotocoagulation in a Boston keratoprosthesis type II patient. This patient with ocular cicatricial pemphigoid had pars plana endoscopic cyclophotocoagula through wounds created in the eyelids.This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal...
January 10, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28079655/microarchitecture-of-schlemm-canal-before-and-after-selective-laser-trabeculoplasty-in-enhanced-depth-imaging-optical-coherence-tomography
#19
Alon Skaat, Michael S Rosman, Jason L Chien, Mark P Ghassibi, Jeffrey M Liebmann, Robert Ritch, Sung Chul Park
PURPOSE: To characterize the in vivo effect of selective laser trabeculoplasty (SLT) on the Schlemm canal (SC) in eyes with primary open-angle glaucoma (POAG). MATERIALS AND METHODS: Eighty-one serial horizontal enhanced depth imaging optical coherence tomograph B-scans (interval between B-scans, ∼35 μm) of the nasal corneoscleral limbus were obtained before and 4 weeks after SLT. Fifty B-scans in the overlapping regions before and after SLT were selected for analysis based on the structures of aqueous and blood vessels as landmarks...
January 10, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28079654/retinal-oximetry-in-subjects-with-glaucomatous-hemifield-asymmetry
#20
Zhu Li Yap, Charles Ong, Yi Fang Lee, Andrew Tsai, Clarissa Cheng, Monisha E Nongpiur, Shamira A Perera
PURPOSE: Although some studies suggest a strong link between retinal vessel oxygenation and damage to the retinal nerve fiber layer (RNFL) seen in glaucoma, it has yet to be conclusively proven. This study compares intraocular retinal oximetry in glaucomatous eyes displaying asymmetrically affected hemifields across different subgroups of glaucoma, namely primary angle closure glaucoma (PACG), primary open-angle glaucoma (POAG), and normal tension glaucoma (NTG). METHODS: In this prospective cross-sectional study, 99 patients (PACG, n=28; POAG, n=37; NTG, n=34) underwent retinal oxygenation and vessel caliber measurements using the Oxymap T1 Retinal Oximeter, Cirrus optical coherence tomography, and Humphrey visual field testing...
January 10, 2017: Journal of Glaucoma
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