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Journal of Glaucoma

John F Doane, Jace J Rickstrew, James Quinten Tuckfield, Jae E Cauble
PURPOSE: To determine the prevalence of pigment dispersion syndrome (PDS) in patients presenting for vision correcting refractive surgery. SETTING: Discover Vision Centers, Kansas City, Missouri, USA DESIGN:: Prospective Case Series. METHODS: A total of 637 eyes of 319 serial patients who presented seeking refractive surgery were included in this prospective, observational study. Patients underwent routine ophthalmologic exam prior to refractive surgery...
January 15, 2019: Journal of Glaucoma
Paula Anne Newman-Casey, John A Musser, Leslie M Niziol, Michele M Heisler, Shivani S Kamat, Manjool M Shah, Nish Patel, Amy M Cohn
PURPOSE: To use lean analysis to identify how often and when wait times occur during a glaucoma visit to identify opportunities for additional patient engagement. METHODS: This prospective observational time-motion study measured process and wait times for 77 patient visits from 12 ophthalmologists at an academic glaucoma clinic over a 3-month period. Value stream maps visually diagrammed the process of a clinic visit from the patient's perspective. Descriptive statistics were calculated for process times, wait times, and the frequency of 10+ minute wait times during each part of the visit...
January 11, 2019: Journal of Glaucoma
Carlo Alberto Cutolo, Carlos Gustavo De Moraes, Jeffrey M Liebmann, Kaweh Mansouri, Carlo Enrico Traverso, Robert Ritch
PURPOSE: We investigated the effect of different intraocular pressure (IOP)-lowering interventions on contact lens sensor (CLS) parameters and their relationship with Goldman applanation tonometer (GAT)-measured IOP reduction. METHODS: Data from reliable CLS recordings performed before and after IOP-lowering interventions were analyzed. Three interventions were evaluated: topical medications, laser trabeculoplasty, and incisional surgery. A set of 115 different CLS parameters were derived from 24-hour curves...
January 11, 2019: Journal of Glaucoma
Ricardo Augusto Paletta Guedes, Daniela Marcelo Gravina, Vanessa Maria Paletta Guedes, Alfredo Chaoubah
AIM: To assess the efficacy and safety of the Ologen™ collagen matrix as an adjuvant for combined phacoemulsification and non-penetrating deep sclerectomy (Phaco-NPDS), in addition to mitomycin C (MMC). METHODS: This was a longitudinal retrospective comparative study of eyes treated with Phaco-NPDS, with (Group 1) or without (Group 2) an Ologen™ collagen matrix implant, in addition to MMC. The main outcome measures were operative success [absolute success: intraocular pressure (IOP) <18▒mm Hg and an at least 20% reduction from baseline without medication; relative success: IOP <18▒mm Hg and at least 20% reduction from baseline IOP with or without medication]; mean reductions (%) in IOP and medication use; number of postoperative reinterventions (goniopuncture, needling, reoperation); and number of complications...
January 8, 2019: Journal of Glaucoma
Do Young Park, Sung Yoon Cho, Dong-Kyu Jin, Changwon Kee
PURPOSE: We aimed to present a comprehensive assessment of the ophthalmic characteristics of genetically confirmed oculodentodigital dysplasia (ODDD) in four members of a single Korean family across three generations. PATIENTS AND METHODS: The characteristics of four affected ODDD patients were evaluated. Comprehensive ophthalmic and medical examinations were performed in three patients including the proband, together with genetic analysis, and retrospective chart review was conducted for an affected ancestor...
January 8, 2019: Journal of Glaucoma
Xiongfei Liu, Simon K Law
PURPOSE: To evaluate the outcomes of autologous limbus-hinged partial-thickness scleral flap and half-moon-shaped split-thickness donor corneal allograft in management of tube erosion of glaucoma drainage device (GDD). METHODS: Consecutive patients who had undergone a limbus-hinged partial-thickness scleral flap and half-moon-shaped split-thickness corneal graft were reviewed. Primary outcome was surgical success of coverage of the exposed tube without complications or additional surgeries...
January 8, 2019: Journal of Glaucoma
Rudrani Banik, Mark J Kupersmith, Jui-Kai Wang, Mona K Garvin
PURPOSE: Acetazolamide (ACZ) lowers IOP, acutely in normal eyes and both acutely and chronically in eyes with glaucoma, and cerebrospinal fluid pressure (CSFp), chronically in patients with idiopathic intracranial hypertension (IIH). We hypothesize chronic daily ACZ would significantly reduce IOP and contribute to a translaminar pressure gradient change reflected by alteration in the CSFp-IOP difference and the deformation of the neural canal in patients with IIH and no glaucoma. METHODS AND PATIENTS: Prior to randomization to ACZ or placebo treatment for six months, 165 participants in the IIH Treatment Trial had evaluations that included Goldmann applanation, CSFp measurement, and OCT determination of the neural canal deformation...
January 7, 2019: Journal of Glaucoma
Anani Plamenov Toshev, Alexander Karl-Georg Schuster, Shahzada Najam Ul Hassan, Norbert Pfeiffer, Esther Maria Hoffmann
PURPOSE: To examine vessel density (VD) properties of the optic nerve head (ONH) in eyes with ocular hypertension (OHT), high-tension glaucoma (HTG) and normal-tension glaucoma (NTG) and to evaluate associations on structural parameters of retinal nerve fiber layer (RNFL). METHODS: Three groups of patients with OHT (n=15), HTG (n=36) and NTG (n=22), and a healthy control group (n=23) were included in this study. Peripapillary VD and optic disc flow area were measured using optical coherence tomography angiography, and peripapillary RNFL thickness was determined...
January 7, 2019: Journal of Glaucoma
Dolly S Chang, Karun Arora, Michael V Boland, David S Friedman
PURPOSE: To assess the relationship between pupillary light reflex and estimated retinal ganglion cell (RGC) counts in patients with glaucoma. METHODS: We recorded and analyzed pupil responses using an automated binocular pupillometer in 148 patients with glaucoma (mean age 67±11, 49% female) and 71 controls (age 60±9.6, 69% female) as part of a prospective clinical study. The amplitude of pupil constriction was calculated as the percentage change in pupil diameter between constriction onset and peak constriction in response to controlled stimuli...
January 7, 2019: Journal of Glaucoma
Jae Hwan Choi, Jong Chul Han, Changwon Kee
PURPOSE: To evaluate whether optic nerve head (ONH) tilt has relations with the visual field (VF) defect in myopic normal tension glaucoma (NTG). METHODS: Comparisons of variables were performed between less and more advanced VF defect groups in bilateral myopic NTG. Vertical, horizontal, maximal ONH tilt angles and angular location of maximal ONH tilt were measured using fundus photography and spectral-domain (SD) optical coherence tomography (OCT). Logistic regression analysis was performed to evaluate variables associated with more advanced VF defect in bilateral myopic NTG...
January 7, 2019: Journal of Glaucoma
Pooja Patel, Alon Harris, Carol Toris, Leslie Tobe, Matthew Lang, Aditya Belamkar, Adrienne Ng, Alice C Verticchio Vercellin, Sunu Mathew, Brent Siesky
No abstract text is available yet for this article.
December 28, 2018: Journal of Glaucoma
Kevin Gillmann, Giorgio Enrico Bravetti, Kaweh Mansouri
No abstract text is available yet for this article.
December 28, 2018: Journal of Glaucoma
Harsha L Rao, Shruthi Sreenivasaiah, Shivani Dixit, Mohammed Riyazuddin, Srilakshmi Dasari, Jayasree P Venugopal, Zia S Pradhan, Narendra K Puttaiah, Sathi Devi, Kaweh Mansouri, Carroll Ab Webers, Robert N Weinreb
PURPOSE: To compare the prevalence of choroidal microvascular dropout (CMvD) in primary open angle glaucoma (POAG) eyes with and without disc hemorrhage (DH). METHODS: In a cross-sectional study, 44 eyes of 44 control subjects, 32 eyes of 32 POAG patients with DH and 41 eyes of 41 POAG patients without DH underwent visual fields (VF), optical coherence tomography (OCT) and OCT angiography (OCTA). Presence of CMvD was evaluated on the choroidal OCTA slab. VF defect in the glaucoma eyes were classified into initial nasal defect (IND), initial parafoveal scotoma (IPFS) and combined nasal and parafoveal defect...
December 28, 2018: Journal of Glaucoma
Bo Ram Seol, Joo Young Shin, Sangkyung Choi, Tae Gu Kang, Jin Wook Jeoung, Ki Ho Park
PURPOSE: To evaluate the early-postoperative intraocular pressure (IOP) changes and frequency of IOP spike after cataract surgery in normal-tension glaucoma (NTG) eyes and to compare them with those of non-glaucomatous eyes. METHODS: This was a case-control study. We reviewed the medical records of patients who had undergone cataract surgery. One-to-one (1:1) case matching was performed, each matched set consisting of one NTG and one non-glaucomatous eye as the control eye...
December 28, 2018: Journal of Glaucoma
David Kuerten, Matthias Fuest, Marion Bienert, Peter Walter, Niklas Plange
PURPOSE: To evaluate ocular hemodynamics in patients with a disease believed to be related to a chronic vascular damage (i.e. normal tension glaucoma, NTG) in comparison to an entity with an acute ischemic impact on the optic nerve (i.e. acute nonarteritic ischemic optic neuropathy, NAION). METHODS: Blood flow velocities (peak systolic velocity (PSV), end-diastolic velocity (EDV)) of the ophthalmic artery (OA), central retinal artery (CRA) and nasal and temporal posterior ciliary arteries (PCAs) were measured via color Doppler imaging (CDI)...
December 28, 2018: Journal of Glaucoma
Karen Zaarour, Youssef Abdelmassih, Nicolas Arej, Karim Tomey, Ziad Khoueir
PURPOSE: This study aims at evaluating the intermediate-term efficacy and safety of micropulse transscleral cyclophotocoagulation (MP-TSCPC) in cases of uncontrolled glaucoma. METHODS: Patients with moderate to advanced glaucoma and uncontrolled intraocular pressure (IOP) despite maximally tolerable anti-glaucoma medications were selected to undergo MP-TSCPC, using the MP3 handpiece with the Iridex IQ810 (IRIDEX Laser Systems, Mountain View, CA). Follow-up examinations took place on a regular basis until 15 months postoperatively...
December 28, 2018: Journal of Glaucoma
Rafaella Nascimento E Silva, Carolina A Chiou, Mengyu Wang, Haobing Wang, Marissa K Shoji, Jonathan C Chou, Erica E D'Souza, Scott H Greenstein, Stacey C Brauner, Milton R Alves, Louis R Pasquale, Lucy Q Shen
PURPOSE: To assess optic nerve head (ONH) and peripapillary microvasculature in primary open angle glaucoma (POAG) of mild to moderate severity using swept-source optical coherence tomography angiography (SS-OCTA). METHODS: In a cross-sectional study, SS-OCTA images were analyzed for one eye from each of 30 POAG patients with glaucomatous Humphrey visual field (VF) loss and 16 controls. The anatomic boundary of ONH was manually delineated based on Bruch's membrane opening and large vessels were removed from en face angiography images to measure vessel density and the Integrated OCTA by ratio analysis Signal (IOS), suggestive of flow, in the ONH and peripapillary region...
December 24, 2018: Journal of Glaucoma
Mary Qiu, Pradeep Y Ramulu, Michael V Boland
PURPOSE: To investigate the relationship between glaucoma and sleep in United States adults. PATIENTS AND METHODS: This cross-sectional study included 6,784 from the 2005-2008 National Health and Nutrition Examination Survey aged ≥40 years who completed the sleep survey. Predictors included sleep duration, sleep latency, sleep disorders, sleep disturbances, sleep medication use, and daytime dysfunction due to sleepiness. Outcomes included disc defined glaucoma (either right or left disc demonstrating glaucomatous features) and visual field defects (VFD) assessed by Frequency Doubling Technology perimetry...
December 24, 2018: Journal of Glaucoma
Ayesha Mohd Zain, Umi Kalthum Md Noh, Salina Hussein, Jemaima Che Hamzah, Safinaz Mohd Khialdin, Norshamsiah Md Din
PURPOSE: To investigate the association between long-term intranasal steroid use and intraocular pressure (IOP) elevation. PATIENTS AND METHODS: One hundred eyes from 50 patients on long-term intranasal steroids(>2▒y) for allergic rhinitis and 90 eyes from 45 controls were included in this study. Patients on other forms of steroids and risk factors for glaucoma were excluded. IOP was measured and non-mydriatic stereoscopic optic disc photos were taken for each eye...
December 24, 2018: Journal of Glaucoma
Francesco Stringa, Zaria Ali, Savvas Christou, Sumita Karandikar, Vikas Shankar
A 78 old male with angle closure glaucoma and on treatment with oral anticoagulants, underwent phacoemulsification. An early acute suprachoroidal hemorrhage (SCH) occurred and the surgical wound was rapidly sutured without complete soft lens matter (SLM) removal, nor insertion of intraocular lens (IOL). The SCH was managed conservatively and it resolved in 5 weeks; the intraocular pressure was 35▒mm Hg despite maximal medical treatment. Secondary SLM removal followed by IOL implantation combined with XEN45 was then performed...
December 24, 2018: Journal of Glaucoma
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