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Journal of Glaucoma

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https://www.readbyqxmd.com/read/28731936/case-series-keratolimbal-allograft-as-a-patch-graft-for-glaucoma-drainage-devices
#1
Sarah F Ahmed, Mason Schmutz, Sameh Mosaed
PURPOSE: Tube exposure remains one of the most common complications after glaucoma drainage device (GDD) implantation, despite various types of patch grafts available today. We present a 4 patient case series following the effectivity of the keratolimbal allograft (KLAL) as a patch graft for cases of tube exposure. Given its inherent population of stem cells, our hypothesis was that this highly replicative, biological tissue would provide an adequate means of glaucoma tube coverage. The subset of patients chosen for the KLAL patch graft all had a history of abnormally scarred conjunctiva or thin sclera...
July 20, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28731935/predictive-value-of-the-water-drinking-test-and-the-risk-glaucomatous-visual-field-progression
#2
Carlos G De Moraes, Remo Susanna, Lisandro M Sakata, Marcelo Hatanaka
PURPOSE: The purpose of this is to test the hypothesis the intraocular pressure (IOP) peaks during a stress test [the water drinking test (WDT)] can estimate the risk of future visual field progression in treated primary open-angle glaucoma (POAG) patients. PATIENTS AND METHODS: Design: Prospective, longitudinal study. SETTING: Clinical practice. STUDY POPULATION: Treated POAG patients whose IOP was ≤18 mm Hg and who had no IOP-lowering interventions between the date of the WDT and the last eligible visual field...
July 20, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28731934/long-term-evaluation-of-specular-microscopic-changes-following-nd-yag-iridotomy-in-chronic-primary-angle-closure-glaucoma-eyes
#3
Ramanjit Sihota, Esha Agarwal, Mathew James, Meena Verma, Lalit Kumar, Tanuj Dada, Viney Gupta, Kulwant Singh Kapoor
AIM: The aim of this study was to evaluate specular microscopy of chronic primary angle-closure glaucoma (CPACG) eyes at least 1 year after Nd:YAG iridotomy, and compare them with CPACG eyes without an iridotomy and age-matched, normal eyes. PATIENTS AND METHOD: Consecutive patients of CPACG at the Glaucoma service were screened. All patients underwent slit-lamp biomicroscopy, +90 D examination, and applanation tonometry. A total of 100 eyes of 100 consecutive patients of CPACG with an Nd:YAG iridotomy performed ≥1 year before, who met all inclusion/exclusion criteria, 60 consecutive CPACG eyes without an iridotomy, and 60 age and refraction-matched control eyes were enrolled...
July 20, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28692594/measuring-rates-of-visual-field-progression-in-linear-versus-nonlinear-scales-implications-for-understanding-the-relationship-between-baseline-damage-and-target-rates-of-glaucoma-progression
#4
Kevin Liebmann, Carlos Gustavo De Moraes, Jeffrey M Liebmann
PURPOSE: The purpose of this study is to test the hypothesis that the relationship between baseline visual field damage and the rate of progression depends upon the use of logarithmic (dB) versus linear (1/Lambert) scale. METHODS: A total of 60 eyes (60 patients) with treated, established glaucoma and at least 5 reliable 24-2 visual fields were included. Baseline visual field mean deviation (MD) in dB was transformed to 1/Lambert using standard equation. Mixed effects linear regression was used to calculate the slopes (MD rates of progression over time) with linear and nonlinear scales...
July 20, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28719418/comparison-of-glaucoma-progression-between-unilateral-and-bilateral-disc-hemorrhage-eyes-and-associated-risk-factors-for-progression
#5
Bo Ram Seol, Young Kook Kim, Jin Wook Jeoung, Ki Ho Park
PURPOSE: To compare glaucoma progression between unilateral and bilateral disc hemorrhage (DH) eyes and to determine the associated risk factors. METHODS: A total of 78 bilateral primary open-angle glaucoma (POAG) patients who had shown one or more occurrences of DH (48 eyes of 38 unilateral DH patients and 30 eyes of 30 bilateral DH patients) were included. Glaucoma progression was defined by visual field (VF) deterioration. The mean VF global indices progression rates in the pre-DH, post-DH and total follow-up periods were compared between the unilateral and bilateral DH groups...
July 17, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28719417/anterior-chamber-angle-and-trabecular-meshwork-measurements-made-by-fourier-domain-optical-coherence-tomography-in-healthy-white-children
#6
José I Fernández-Vigo, Lucía De-Pablo-Gómez-de-Liaño, Cristina Fernández-Vigo, Gabriel Arcos-Villegas, Cristina Fernández-Pérez, Julián García-Feijóo, José Á Fernández-Vigo
PURPOSE: To obtain anterior chamber angle and trabecular meshwork (TM) measurements by Fourier-domain optical coherence tomography (FD-OCT) in a population of healthy white children. MATERIALS AND METHODS: This was a cross-sectional study examining 409 right eyes of 409 children. Trabecular-iris angle (TIA) and TM length and area were measured by FD-OCT (RTVue 100) in the nasal and temporal quadrants to analyze correlations between angle or TM measurements and age, sex, and refractive error...
July 17, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28719416/the-ophthalmology-surgical-competency-assessment-rubric-for-trabeculectomy
#7
Catherine M Green, Sarwat Salim, Deepak P Edward, Raghu C Mudumbai, Karl Golnik
PURPOSE: To produce an internationally valid tool to assess skill in performing trabeculectomy surgery. METHODS: A panel of 5 experts developed a tool for assessing trabeculectomy surgery by using a modified Dreyfus scale of skill acquisition and providing descriptors for each level of skill for each category. The tool was then reviewed by a panel of 10 international content experts for their constructive comments, which were incorporated into the final rubric tool...
July 17, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28692597/practice-preferences-for-glaucoma-surgery-a-survey-of-the-american-glaucoma-society
#8
Kateki Vinod, Steven J Gedde, William J Feuer, Joseph F Panarelli, Ta C Chang, Philip P Chen, Richard K Parrish
PURPOSE: The purpose of this study is to assess surgical practice patterns among the American Glaucoma Society (AGS) membership. METHODS: An anonymous online survey evaluating the use of glaucoma surgeries in various clinical settings was redistributed to AGS members. Survey responses were compared with prior results from 1996, 2002, and 2008 to determine shifts in surgical practice patterns. Questions were added to assess the preferred approach to primary incisional glaucoma surgery and phacoemulsification combined with glaucoma surgery...
July 7, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28692596/inadvertent-cyclodialysis-cleft-and-hypotony-following-ab-interno-trabeculotomy-using-the-trabectome-device-requiring-surgical-repair
#9
Thomas A Berk, Jella A An, Iqbal Ike K Ahmed
PURPOSE: To report the first case of inadvertent cyclodialysis cleft and hypotony requiring surgical repair following ab-interno trabeculotomy (AIT) using the Trabectome device, and the postoperative clinical results following direct suture cyclopexy. METHODS: A 55-year-old man with hypotonous maculopathy secondary to cyclodialysis cleft inadvertently created 3 years earlier during AIT using the Trabectome device was referred for repair. Direct suture cyclopexy was performed and topical homatropine and dexamethasone drops were prescribed postoperatively...
July 7, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28692595/the-quantitative-measurements-of-vascular-density-and-flow-area-of-optic-nerve-head-using-optical-coherence-tomography-angiography
#10
Fatemeh Bazvand, Reza Mirshahi, Kaveh Fadakar, Houshangh Faghihi, Siamak Sabour, Fariba Ghassemi
PURPOSE: The purpose of this study was to evaluate the vascular density (VD) and the flow area on optic nerve head (ONH) and peripapillary area, and the impact of age and sex using optical coherence tomography angiography (OCTA) in healthy human subjects. METHODS: Both eyes of each volunteer were scanned by an RTVue XR Avanti; Optovue with OCTA using the split-spectrum amplitude-decorrelation angiography algorithm technique. Masked graders evaluated enface angiodisc OCTA data...
July 7, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28671928/examiner-handedness-and-the-effects-on-intraocular-pressure-readings-using-the-tono-pen-xl
#11
Alexander G Hacopian, Lauren C Rushing, Alice Z Chuang, Nicholas P Bell, Kartik S Kumar, Robert M Feldman
PURPOSE: To assess the effect of examiner handedness on intraocular pressure (IOP) readings using the Tono-Pen XL in eyes without corneal pathology or previous ocular surgeries. PATIENTS AND METHODS: Patients 18 years of age or older were included in this prospective study. Participants who had a history of corneal conditions or other characteristics that would prevent reliable IOP measurements were excluded. Five experienced examiners, 2 right-hand dominant and 3 left-hand dominant, took bilateral IOP measurements with a Tono-Pen XL...
June 30, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28671927/micropulse-cyclophotocoagulation-initial-results-in-refractory-glaucoma
#12
Matthew E Emanuel, Davinder S Grover, Ronald L Fellman, David G Godfrey, Oluwatosin Smith, Michelle R Butler, Helen L Kornmann, William J Feuer, Swati Goyal
PURPOSE: The purpose of this study is to evaluate the use of micropulse transscleral cyclophotocoagulation (MP-TSCPC), a new and increasingly popular treatment, in patients with uncontrolled glaucoma. METHODS: A retrospective chart review was performed for all patients who underwent a MP-TSCPC at the Glaucoma Associates of Texas. RESULTS: A total of 84 eyes were treated with MP-TSCPC in this study with a mean follow-up time of 4.3 months. The mean age of treated patients was 74 years and 48 (57%) were female...
June 30, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28671926/high-altitude-associated-changes-in-intraocular-pressure-abrogated-by-trabeculectomy
#13
William Foulsham, Andrew J Tatham
PURPOSE: To highlight the effect of ascent to high altitude on intraocular pressure (IOP) in a patient with primary open-angle glaucoma, who had previously undergone trabeculectomy in 1 eye. METHODS: Case report. RESULTS: A 66-year-old mountaineer with primary open-angle glaucoma and previous right trabeculectomy performed self-tonometry using a rebound tonometer (Icare HOME) before and during an expedition in the Himalaya. In the nonoperated eye, there was a statistically significant increase in IOP as the patient ascended to 5000 m over 8 days (R=0...
June 30, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28671925/ophthalmic-timolol-hallucinations-a-case-series-and-review-of-the-literature
#14
Tavish Nanda, Nailyn Rasool, Alison B Callahan, Robert L Stamper, Jeffrey G Odel
PURPOSE: Systemic absorption and central nervous system (CNS) penetration of timolol drops are a well-studied phenomenon, resulting in common side effects such as bradycardia, bronchospasm, fatigue, and confusion. More serious CNS side effects, such as psychosis and depression, however, are rarely attributed to eye drops. We report a case series in which patients developed visual hallucinations secondary to topical ocular timolol use. METHODS: This study is a case series and review of the literature...
June 30, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28671924/long-term-outcome-of-surgical-treatment-for-late-intraocular-lens-dislocation-associated-with-high-intraocular-pressure-a-case-series
#15
Lucas A Torres, Jayme R Vianna, Marcelo T Nicolela
PURPOSE: To demonstrate the long-term safety and efficacy of transscleral intraocular lens (IOL) fixation combined with an Ahmed glaucoma drainage device implantation for patients with late IOL dislocation and high intraocular pressure (IOP). METHODS: This is a retrospective report of a series of patients who underwent this combined surgery. The main outcome variables studied were change in visual acuity (VA), IOP, and number of medications compared with preoperative levels...
June 30, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28671923/lncrnas-dna-methylation-and-the-pathobiology-of-exfoliation-glaucoma
#16
William M Johnson, Laura K Finnegan, Michael A Hauser, W Daniel Stamer
Exfoliation glaucoma (XFG) is a clinically aggressive and genetically distinct form of glaucoma that results in neuronal death and irreversible blindness. Gene variants associate with many neurodegenerative diseases including XFG, Parkinson's disease (PD) and Alzheimer's disease (AD). Intriguingly, variants found within the same gene can either confer risk for or provide protection against all 3 of these diseases, complicating the genetic component of pathology. Unfortunately, studies that examine proteins encoded by genes having relevant variants have failed to produce therapeutic interventions that slow or stop the progression of XFG, PD, or AD in patients...
June 30, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28671922/a-case-of-bilateral-pigment-dispersion-syndrome-following-many-years-of-uninterrupted-treatment-with-atropine-1-for-bilateral-congenital-cataracts
#17
Corrado Gizzi, Jibran Mohamed-Noriega, Ian Murdoch
PURPOSE: Describe an unusual case of bilateral pigment dispersion syndrome (PDS) following years of uninterrupted treatment with atropine 1% for bilateral congenital cataracts, speculate on potential mechanisms leading to this condition. DESIGN: This is a case report. CASE: A 45-year-old white patient on long-term treatment with atropine 1% ointment since his infancy for bilateral congenital cataracts developed PDS with secondary ocular hypertension...
June 30, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28671921/papilloschisis-a-case-report
#18
Lina Osman, Sundeep Deol, Diana Mather, Subhanjan Mukherji
We report a case of papilloschisis, where the schisis is noted within the optic nerve tissue with no associated disc pit. This has not been reported in the literature to the best of our knowledge.
June 30, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28671920/adherence-to-follow-up-recommendations-among-individuals-in-the-philadelphia-glaucoma-detection-and-treatment-project
#19
Lisa A Hark, Benjamin E Leiby, Michael Waisbourd, Jonathan S Myers, Scott J Fudemberg, Anand V Mantravadi, Yang Dai, John P Gilligan, Arthur F Resende, L Jay Katz
PURPOSE: To evaluate rates of adherence to free follow-up eye exam appointments among participants in the Philadelphia Glaucoma Detection and Treatment Project. PATIENTS AND METHODS: Ophthalmologists and testing equipment were brought directly to participants at risk for glaucoma at 43 community sites in Philadelphia. Those diagnosed with glaucoma-related pathology were recommended to return for follow-up to be reexamined on site. Rates of adherence and clinical and demographic risk factors for adherence were evaluated...
June 30, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28671919/evaluation-of-layer-by-layer-segmented-ganglion-cell-complex-thickness-for-detecting-early-glaucoma-according-to-different-macular-grids
#20
Hae Jin Kim, Ki Ho Park, Young Kook Kim, Jin Wook Jeoung
PURPOSE: To investigate the diagnostic performance of layer-by-layer segmented macular ganglion cell complex (GCC) thickness for detecting early glaucoma using spectral-domain optical coherence tomography (SD-OCT) with different macular grids. MATERIALS AND METHODS: Sixty-two early-stage open-angle glaucoma patients and 70 healthy subjects were enrolled in this study. The SD-OCT with automated segmentation was used to obtain macular scans with different grids of "1, 2, and 3 mm"; "1, 2...
June 30, 2017: Journal of Glaucoma
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