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Journal of Glaucoma

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https://www.readbyqxmd.com/read/29045333/relationship-between-optic-nerve-head-drusen-volume-and-structural-and-functional-optic-nerve-damage
#1
Alon Skaat, Stephanie Muylaert, Rachel S Mogil, Rafael L Furlanetto, Camila F Netto, Rudrani Banik, Jeffrey M Liebmann, Robert Ritch, Sung Chul Park
PURPOSE: To assess the relationships between optic nerve head drusen (ONHD) volume, retinal nerve fiber layer (RNFL) thickness and visual field (VF) loss. METHODS: Patients with ONHD and no other ocular or systemic conditions that can affect RNFL or VF were enrolled. Serial enhanced depth imaging (EDI) optical coherence tomography (OCT) B-scans of the optic nerve head (interval between scans, ~30 μm) were obtained from each participant. ONHD volume was calculated for each eye by delineating the ONHD masses in each OCT B-scan using 3-dimensional reconstruction software...
October 17, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/29045332/sutureless-deep-sclerectomy-a-preliminary-report
#2
Ahmed M Abdelrahman, Rasha El-Tanamly, Mohamed Sabry
The study describes a modification of the deep sclerectomy making it completely sutureless with a 6 months follow up period. This is a prospective pilot phase that included 24 eyes of 16 patients, 13 males and 3 females with medically uncontrolled Open Angle Glaucomas (OAG) despite maximally tolerated medical therapy. After excising the deep flap, no sutures are added to the superficial scleral flap or to the conjunctiva. A statically significant reduction of the IOP was reported during all the follow visits without serious complications...
October 17, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/29045331/test-conditions-in-macular-visual-field-testing-in-glaucoma
#3
Mariko Eura, Chota Matsumoto, Shigeki Hashimoto, Sachiko Okuyama, Sonoko Takada, Hiroki Nomoto, Fumi Tanabe, Yoshikazu Shimomura
PURPOSE: To evaluate the suitable visual field (VF) test conditions (target size, test type, and eccentricity) for the macular region, we investigated the correlations between the ganglion cell layer (GCL) thickness and six VF test results. METHODS: We tested 32 eyes of patients (61.1±9.2 y) with preperimetric (6), early-stage (16), and moderate-stage (10) glaucoma. The VF tests included 3 SAP (the 10-2 HFA using SITA with target size III [HFA SITA (III)], full threshold with size III [HFA FULL (III)] and size I [HFA FULL (I)]) and 3 visual function-specific perimetry tests (the 10-2 SWAP, 10-2 flicker, and 10-2 Humphrey Matrix)...
October 17, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/29045330/simultaneous-implantation-of-an-ahmed-and-baerveldt-glaucoma-drainage-device-for-uncontrolled-intraocular-pressure-in-advanced-glaucoma-comment
#4
Richa Gupta, Surabhi Gupta
No abstract text is available yet for this article.
October 17, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/29045329/hybrid-deep-learning-on-single-wide-field-optical-coherence-tomography-scans-accurately-classifies-glaucoma-suspects
#5
Hassan Muhammad, Thomas J Fuchs, Nicole De Cuir, Carlos G De Moraes, Dana M Blumberg, Jeffrey M Liebmann, Robert Ritch, Donald C Hood
PURPOSE: Existing summary statistics based upon optical coherence tomographic (OCT) scans and/or visual fields (VFs) are suboptimal for distinguishing between healthy and glaucomatous eyes in the clinic. This study evaluates the extent to which a hybrid deep learning method (HDLM), combined with a single wide-field OCT protocol, can distinguish eyes previously classified as either healthy suspects or mild glaucoma. METHODS: In total, 102 eyes from 102 patients, with or suspected open-angle glaucoma, had previously been classified by 2 glaucoma experts as either glaucomatous (57 eyes) or healthy/suspects (45 eyes)...
October 17, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/29045328/reversible-venting-stitch-for-fenestrating-valve-less-glaucoma-shunts
#6
Handan Akil, Priscilla Q Vu, Anhtuan H Nguyen, Alexander Nugent, Vikas Chopra, Brian A Francis, James C Tan
PURPOSE: To describe a venting stitch modification for valveless glaucoma aqueous shunts and characterize early postoperative intraocular pressure (IOP) and glaucoma medication use following the modification. MATERIALS AND METHODS: Retrospective chart review of 61 sequential patients undergoing Baerveldt Glaucoma Implant (BGI)-350 implantation at the Doheny Eye Institute. Twenty four patients received a glaucoma shunt with venting stitch modification (modified BGI) and 37 patients received an unmodified shunt (BGI-only)...
October 17, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/29035913/the-water-drinking-test-and-glaucoma-progression-considerations-regarding-the-test-usefulness-as-an-independent-risk-assessment-tool
#7
Tiago Santos Prata, Diego Torres Dias
No abstract text is available yet for this article.
October 13, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/29035912/surgical-outcomes-of-gonioscopy-assisted-transluminal-trabeculotomy-gatt-in-patients-with-open-angle-glaucoma
#8
Kamran Rahmatnejad, Noelle L Pruzan, Sarah Amanullah, Bilal A Shaukat, Arthur F Resende, Michael Waisbourd, Tingting Zhan, Marlene R Moster
PURPOSE: To evaluate the efficacy and safety of gonioscopy-assisted transluminal trabeculotomy (GATT) in patients with open-angle glaucoma. METHODS AND PARTICIPANTS: A retrospective chart review of adult patients who underwent GATT due to inadequately controlled intraocular pressure (IOP) or intolerance to medication. Main outcome measures were success rate, IOP and number of glaucoma medications. Success was defined as IOP reduction >20% from baseline or IOP between 5-21 mmHg, and no need for further glaucoma surgery...
October 13, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/29035911/ab-interno-gel-implant-for-the-treatment-of-glaucoma-patients-with-or-without-prior-glaucoma-surgery-one-year-results
#9
Fritz H Hengerer, Thomas Kohnen, Michael Mueller, Ina Conrad-Hengerer
PURPOSE: To evaluate IOP lowering effects and complication management of an ab interno gel implant for the treatment of patients refractory to anti-glaucoma medication or glaucoma surgery. METHODS: Retrospective analysis of the medical records of 242 consecutive eyes of 146 patients with uncontrolled intraocular pressure (IOP) despite maximum tolerated medical therapy or prior surgical intervention that underwent XEN45 implantation (as sole procedure or in combination with cataract surgery) between March 2014 and June 2015...
October 13, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/29016522/spontaneous-resolution-of-delayed-suprachoroidal-hemorrhage-in-the-single-eye-following-needling-in-congenital-glaucoma
#10
Jasmin Rezapour, Esther M Hoffmann, Verena Prokosch-Willing, Adrian Gericke, Norbert Pfeiffer
INTRODUCTION: Suprachoroidal hemorrhage is a rare, but potentially vision-threatening event with poor long-term visual prognosis. At present, there is disagreement whether surgical intervention or conservative treatment is superior in the management. We report on a case of spontaneous resolution of severe SCH after needling procedure in the only eye of a young patient with congenital glaucoma. CASE PRESENTATION: A 43-year-old woman with congenital glaucoma was scheduled for bleb needling in her only eye...
October 9, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/29016521/glaucoma-diagnostic-capabilities-of-foveal-avascular-zone-parameters-using-optical-coherence-tomography-angiography-according-to-visual-field-defect-location
#11
Junki Kwon, Jaewan Choi, Joong Won Shin, Jiyun Lee, Michael S Kook
PURPOSE: To assess the diagnostic ability of foveal avascular zone (FAZ) parameters to discriminate glaucomatous eyes with visual field defects (VFDs) in different locations (central vs. peripheral) from normal eyes. PATIENTS AND METHODS: Totally, 125 participants were separated into three groups: normal (n=45), glaucoma with peripheral VFD (PVFD, n=45), and glaucoma with central VFD (CVFD, n=35). The FAZ area, perimeter, and circularity and parafoveal vessel density were calculated from optical coherence tomography angiography images...
October 9, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/29016520/episcleral-venous-outflow-a-potential-outcome-marker-for-istent-surgery
#12
Cristina Bostan, Paul Harasymowycz
PURPOSE: (1) To propose the use of episcleral venous outflow (EVO) as an outcome marker of iStent surgery, and an EVO grading scale. (2) To determine the association of EVO with: (a) postoperative intraocular pressure (IOP) and medication burden; (b) iStent patency status. PATIENTS AND METHODS: Retrospective cohort study including 151 glaucomatous eyes having undergone iStent-phacoemulsification surgery. Demographic and preoperative data (IOP, number of anti-glaucoma medications, glaucoma type and stage, maximal IOP) were collected...
October 9, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28957960/the-glaucoma-italian-pediatric-study-gipsy-1-year-results
#13
Luciano Quaranta, Elena Biagioli, Ivano Riva, Francesca Galli, Davide Poli, Eliana Rulli, Andreas Katsanos, Antonio Longo, Maurizio G Uva, Valter Torri, Robert N Weinreb
PURPOSE: To investigate the efficacy and safety of a treatment strategy with latanoprost and dorzolamide in primary pediatric glaucoma patients partially responsive to surgery. PATIENTS AND METHODS: Children with primary pediatric glaucoma having postsurgical untreated intraocular pressure (IOP) between 22 and 26 mm Hg were eligible. At baseline, patients were administered latanoprost once daily. Depending on IOP reduction, patients were allocated to continuation of latanoprost monotherapy or addition of dorzolamide twice daily, or switch to dorzolamide monotherapy 3 times daily...
September 27, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28930887/genetic-variant-near-plxdc2-influences-the-risk-of-primary-open-angle-glaucoma-by-increasing-intraocular-pressure-in-the-japanese-population
#14
Fumihiko Mabuchi, Nakako Mabuchi, Mitsuko Takamoto, Yoichi Sakurada, Seigo Yoneyama, Kenji Kashiwagi, Hiroyuki Iijima, Zentaro Yamagata, Makoto Aihara, Takeshi Iwata, Makoto Araie
PURPOSE: To assess the association between the genetic variants that were previously reported to be associated with primary open-angle glaucoma (POAG) in the Japanese population and the phenotypic features. METHODS: Six hundred sixty-one Japanese patients including 417 patients with POAG (normal tension glaucoma [NTG], n=210; high tension glaucoma [HTG], n=207) and 244 control subjects without glaucoma were analyzed for 3 genetic variants: rs547984 (near gene: ZP4), rs7081455 (PLXDC2), and rs7961953 (TMTC2)...
September 19, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28930886/upper-eyelid-splitting-to-facilitate-the-insertion-of-glaucoma-drainage-devices
#15
Lorraine M Provencher, Keith D Carter, Jeffrey A Nerad, Wallace L M Alward
PURPOSE: To describe a new application for vertical splitting of the upper eyelid, a technique traditionally used for orbital access, in order to facilitate glaucoma drainage device implantation in patients with poor surgical exposure. METHODS: Case series. CASES: We present a case of Möbius syndrome with complete restriction of the extraocular muscles, followed by a case of cicatricial narrowing of the palpebral fissures due to chronic allergic dermatitis...
September 19, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28930885/author-response-regarding-simultaneous-implantation-of-an-ahmed-and-baerveldt-glaucoma-drainage-device-for-uncontrolled-intraocular-pressure-in-advanced-glaucoma
#16
Veena Rao, Pratap Challa
No abstract text is available yet for this article.
September 19, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28930884/rate-of-macular-ganglion-cell-inner-plexiform-layer-thinning-in-glaucomatous-eyes-with-vascular-endothelial-growth-factor-inhibition
#17
Won June Lee, Young Kook Kim, Yong Woo Kim, Jin Wook Jeoung, Seok Hwan Kim, Jang Won Heo, Hyeong Gon Yu, Ki Ho Park
PURPOSE: To evaluate the rate of progressive macular ganglion cell-inner plexiform layer (GCIPL) thinning in patients with open-angle glaucoma (OAG) who had been treated with intravitreal anti-vascular endothelial growth factor (VEGF) injection for wet age-related macular degeneration (AMD). METHODS: This study was a retrospective modified case control study with fellow-eye comparison. We enrolled bilateral OAG patients who had been treated with repeated anti-VEGF injections for unilateral wet AMD and followed-up on for a minimum of 24 months by Cirrus high-definition optical coherence tomography (HD-OCT)...
September 19, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28930883/reproducibility-and-agreement-of-anterior-segment-parameter-measurements-obtained-using-the-casia2-and-spectralis-oct2-optical-coherence-tomography-devices
#18
Benjamin Y Xu, Derek D Mai, Rafaella C Penteado, Luke Sanders, Robert N Weinreb
PURPOSE: To assess the reproducibility and agreement of measurement values obtained from the Tomey CASIA2 and Heidelberg Spectralis OCT2 anterior segment optical coherence tomography (AS-OCT) devices. METHODS: Twenty eyes from ten subjects ranging from age 28 to 45 years with no history of eye conditions or intraocular surgery were included. Two scans were obtained with each device in a standardized dark-room environment after a period of dark adaptation. One AS-OCT image along the horizontal (temporal-nasal) meridian was analyzed per eye and per scan...
September 19, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28930882/reproducibility-of-bruch-s-membrane-opening-minimum-rim-width-measurements-with-spectral-domain-optical-coherence-tomography
#19
Keunheung Park, Jinmi Kim, Jiwoong Lee
PURPOSE: To evaluate the reproducibility of Bruch's membrane opening-minimum rim width (BMO-MRW) measurements obtained with Spectralis optical coherence tomography (OCT) in normal and glaucoma subjects. METHODS: In total, 123 eyes from 123 subjects (65 healthy, 58 glaucoma subjects) were included. BMO-MRW measurements were repeated three times during the same visit using Spectralis OCT. The BMO points and internal limiting membrane were identified with automated software and corrected manually when necessary...
September 19, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28984717/idiopathic-bilateral-profound-hypotony-in-an-unknown-progressive-neurodegenerative-disorder
#20
Lorraine M Provencher, P Christi Carter, Wallace L M Alward
No abstract text is available yet for this article.
September 3, 2017: Journal of Glaucoma
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