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Journal of Glaucoma

Sergei Muratov, Dominik W Podbielski, Kevin Kennedy, Susan M Jack, Julia Pemberton, Iqbal Ike K Ahmed, Monika Baltaziak, Feng Xie
PURPOSE: To develop a descriptive system for a glaucoma-specific preference-based health-related quality of life (HRQoL) instrument: the Health Utility for Glaucoma (HUG-5). METHODS: The descriptive system was developed in two stages: item identification and item selection. A systematic literature review of HRQoL assessment of glaucoma was conducted using a comprehensive search strategy. Purposeful sampling was used to recruit patients with different clinical characteristics...
May 12, 2018: Journal of Glaucoma
Tarannum Mansoori
No abstract text is available yet for this article.
May 12, 2018: Journal of Glaucoma
Gábor Holló
PURPOSE: To investigate the usefulness of removing the large vessel-related information from peripapillary optical coherence tomography (OCT) angiography progression analysis. Peripapillary vessel density (VD) image series which had shown no progression with an earlier software version that did not separate capillary and large vessel-related effects were reevaluated for selective peripapillary capillary VD progression. METHODS: Prospective retinal nerve fiber layer thickness (RNFLT) and peripapillary VD measurements were made using the Angiovue/RTvue-XR OCT on one eye of 9 normal, 20 under treatment ocular hypertensive (OHT) and 24 under treatment open-angle glaucoma patients at 6-month intervals for 2 years (5 visits)...
May 12, 2018: Journal of Glaucoma
Tomas Bro, Christina Lindén
PURPOSE: To study the intraocular pressure (IOP)-lowering effect of adding brimonidine as the fourth anti-glaucoma medication to a pre-existing therapy of three topical drugs. METHODS: A retrospective, register-based, cohort study of medical records and computerized medical information comprising one county in Sweden. The main outcome measure was change in IOP after brimonidine addition. Short- and long-term effects were evaluated. RESULTS: Out of 4910 patients on anti-glaucoma medication, 69 (1...
May 12, 2018: Journal of Glaucoma
David J Mathew, Graham E Trope, Yvonne M Buys
No abstract text is available yet for this article.
May 11, 2018: Journal of Glaucoma
Pei-Yao Chang, Jiun-Yi Wang, Shu-Wen Chang, Yu-Chia Chang
PURPOSE: To observe the changes in the demand for prescriptions of ocular hypertensive drug (OHD) after cataract surgery, to investigate patterns of change in the required OHD amount in open-angle glaucoma (OAG) and angle-closure glaucoma (ACG) cases and to determine the associated factors related to the change. METHODS: This population-based cohort study using the Taiwan National Health Insurance Research Database enrolled patients with glaucoma who underwent bilateral cataract surgeries within 2 years between 2001 and 2012...
May 11, 2018: Journal of Glaucoma
Do Young Park, Eun Jung Lee, Jong Chul Han, Changwon Kee
PURPOSE: We evaluated the applicability of the ISNT rule using Bruch's membrane opening minimum rim width (BMO-MRW) in healthy eyes and eyes with normal tension glaucoma (NTG). METHODS: 124 healthy eyes and 136 NTG eyes were analyzed. Using two-dimensional disc photographs, neuroretinal rim (NRR) thickness was measured at the superior, inferior, nasal, and temporal sides of the optic disc. Using spectral domain-optical coherence tomography (SD-OCT), BMO-MRW was measured at the same regions...
May 11, 2018: Journal of Glaucoma
Vittoria Aragno, Antoine Labbé, Frédérique Brion, Christophe Baudouin, Pascale Hamard
PURPOSE: To evaluate the efficacy of non-penetrating deep sclerectomy (NPDS) on posture-induced intraocular pressure (IOP) changes in open angle glaucoma (OAG). MATERIALS AND METHODS: Twenty-five eyes of 25 patients with OAG that underwent NPDS were included in this study. IOP was measured with the IcarePro (ICP) tonometer in sitting, supine, dependent lateral decubitus position (DLDP) and non-dependent lateral decubitus position (NDLDP) before surgery, and at 1 and 3 months after surgery...
May 11, 2018: Journal of Glaucoma
Pia Inborr, Mika Harju, Tero T Kivelä
PURPOSE: To quantitate the effect of intravenous hypertonic saline on elevated intraocular pressure (IOP) among three groups of glaucoma patients or suspects. MATERIAL AND METHODS: Forty-four patients with IOP 24-30▒mm Hg; 13 had ocular hypertension (OHT), 14 primary open-angle glaucoma (POAG), and 17 exfoliation glaucoma (ExG). Participants received a bolus of 23.4% intravenous hypertonic saline (1.0▒mmol/kg) through an antecubital vein. We measured IOP, heart rate, and blood pressure before the bolus, afterwards every minute for 10 minutes, and less frequently for 2 hours...
May 10, 2018: Journal of Glaucoma
Mona A Kaleem, Sheila K West, Lily Im, Bonnielin K Swenor
PURPOSE: To determine what criteria are being used by glaucoma specialists to refer patients to low vision services (LVS) and to identify potential barriers to LVS referral. METHODS: A survey was emailed to members of the American Glaucoma Society (AGS). The number and percentage of responses to each survey question were examined. RESULTS: Reported criteria for referral included difficulty performing activities related to vision (78%), degree of visual field loss (63%), and difficulty with orientation and mobility (27%)...
May 10, 2018: Journal of Glaucoma
Nedime Sahinoglu-Keskek, Handan Canan
PURPOSE: To evaluate the changes in choroidal thickness during the use of latanoprost eyedrops which shift fluid to the suprachoroidal space and change choroidal perfusion. METHODS: This prospective study included 34 eyes of 17 bilateral glaucoma or ocular hypertensive patients who had no previous hypotensive therapy. Each patient had both eyes treated with latanoprost. Each patient also underwent a complete ophthalmological examination and optical coherence tomography (OCT) measurement...
May 10, 2018: Journal of Glaucoma
Neha Midha, Kirsten Hoskens, Kaweh Mansouri
PURPOSE: To evaluate safety and efficacy of pattern scanning laser (PASCAL) for peripheral iridoplasty in eyes with plateau iris syndrome. METHODS: Retrospective review of cases that underwent PASCAL peripheral iridoplasty (PLPI). Eyes with plateau iris syndrome confirmed on gonioscopy and ultrasound biomicroscopy were included in the study. Primary and secondary outcome measures were angle widening on gonioscopy and magnitude of IOP reduction, respectively. RESULTS: Twelve eyes of 8 patients that completed one year follow-up were analyzed...
May 10, 2018: Journal of Glaucoma
Hae-Young Lopilly Park, Jiyoung Lee, Chan Kee Park
PURPOSE: To compare standard automated perimetry (SAP) and frequency-doubling technology (FDT) perimetry for detecting macular damage in glaucoma. METHODS: One-hundred-twelve glaucomatous eyes with localized retinal nerve fiber layer (RNFL) defects on red-free photographs and corresponding macular ganglion cell/inner plexiform layer (mGC/IPL) thinning on the deviation map of macular optical coherence tomography (OCT), and thirty-five healthy eyes were enrolled in the study...
May 10, 2018: Journal of Glaucoma
Lawrence S Geyman, Yanin Suwan, Reena Garg, Matthew G Field, Brian D Krawitz, Shelley Mo, Alexander Pinhas, Robert Ritch, Richard B Rosen
PURPOSE: To assess mitochondrial dysfunction in vivo in ocular hypertension (OHT) and primary open-angle glaucoma (POAG) using retinal metabolic analysis. PATIENTS AND METHODS: This was an observational, cross-sectional study performed from November 2015 to October 2016 at the New York Eye and Ear Infirmary of Mount Sinai. Thirty-eight eyes with varying stages of POAG, 16 eyes with OHT, and 32 control eyes were imaged on a custom fundus camera modified to measure full retinal thickness fluorescence at a wavelength optimized to detect flavoprotein fluorescence (FPF)...
May 10, 2018: Journal of Glaucoma
Gábor Holló
PURPOSE: To investigate the potential influence of breath holding on the results of peripapillary vessel density (VD) measurement with optical coherence tomography angiography (OCTA). METHODS: Three peripapillary VD measurements were made at 2-minute intervals on the right eye of 12 healthy young volunteers using the Angiovue/RTvue-XR OCT (software version 2017.1, Phase 7 update) without changing the head and body positions. During the first 2 measurements the volunteers were breathing normally...
May 10, 2018: Journal of Glaucoma
Carlos Gustavo De Moraes, George A Cioffi, Robert N Weinreb, Jeffrey M Liebmann
There is compelling evidence that low systemic blood pressure is associated with glaucoma prevalence and progression. Recently, new guidelines for treatment of systemic hypertension have been implemented and recommend lower target blood pressure. These guidelines may have implications on the rates of glaucoma progression seen in clinical practice and how clinicians should be prepared to identify patients at risk. More importantly, a new paradigm to monitor glaucoma progression is patients treated for systemic hypertension may be warranted in light of these recent changes...
May 10, 2018: Journal of Glaucoma
Claudio I Perez, Sunee Chansangpetch, Max Feinstein, Marta Mora, Anwell Nguyen, Mai Badr, Marisse Masis, Shan C Lin
PURPOSE: To evaluate a novel gonioscopy score as a potential predictor for intraocular pressure (IOP) reduction after cataract surgery. METHODS: Prospective study that included consecutive patients with or without glaucoma, either with open or narrow angles but without peripheral anterior synechiae, who underwent phacoemulsification. Eyes with intraoperative complications and secondary glaucoma were excluded. A preoperative gonioscopy score was created, summing the Shaffer gonioscopy grading in 4 quadrants (range 0-16)...
May 4, 2018: Journal of Glaucoma
Kanika Jain, Amit Kumar Purang, Julie Pegu, Suneeta Dubey
No abstract text is available yet for this article.
May 4, 2018: Journal of Glaucoma
Ramanjit Sihota, Esha Agarwal, Mathew James, Meena Verma, Lalit Kumar, Tanuj Dada, Viney Gupta, Kulwant Singh Kapoor
No abstract text is available yet for this article.
May 4, 2018: Journal of Glaucoma
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