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Journal of Glaucoma

Jung Yong Kim, Ah Reum Jeong, Hee Seung Chin, Na Rae Kim
PURPOSE: To evaluate circulatory melatonin levels by assessing nocturnal urinary excretion of 6-sulfatoxymelatonin (aMT6s) in patients with primary open angle glaucoma (POAG) and to compare the high-tension group and the low-tension group. METHODS: This study included 80 eyes of 41 POAG patients and 87 eyes of 44 control subjects. POAG group was further classified into high-tension group and low-tension group according to the pretreatment intraocular pressure. The first urine in the morning was collected and aMT6s were measured using a commercial ELISA kit...
November 1, 2018: Journal of Glaucoma
Philip P Chen, Kristy L Moeller
PURPOSE: To assess long-term outcomes and complications of smaller-incision trabeculectomy revision with mitomycin (MMC) in glaucoma patients. METHODS: Review of patients undergoing trabeculectomy revision with MMC for inadequate intraocular pressure (IOP) control. After dissection of subconjunctival fibrosis through a smaller (median 5▒mm) incision, MMC was topically applied and episcleral fibrosis was incised. Failure was defined as reoperation for glaucoma, or IOP reduction < 20% over 3 follow up visits...
November 1, 2018: Journal of Glaucoma
Masayuki Kasahara, Nobuyuki Shoji, Kazuhiro Matsumura
PURPOSE: To evaluate the influence of Trabectome surgery on corneal endothelial cells by site METHODS:: Retrospective observational study. Trabectome surgeries were performed on 159 eyes of 132 adult Japanese patients. Corneal endothelial cells were measured at the center (C), inferior (I), nasal inferior (NI), nasal superior (NS), superior (S), temporal superior (TS), and temporal inferior (TI) sectors at <1 month preoperatively and 3, 6, 12, 24, and 36 months postoperatively, for changes in corneal endothelial cell density (ECD), coefficient of variation (CV), and incidence of hexagonal cells (6A)...
November 1, 2018: Journal of Glaucoma
C Gustavo De Moraes, Robert N Weinreb, Jeffrey M Liebmann
No abstract text is available yet for this article.
October 22, 2018: Journal of Glaucoma
Anthony P Khawaja
No abstract text is available yet for this article.
October 22, 2018: Journal of Glaucoma
Man Hu, Huaizhou Wang, Alex S Huang, Li Li, Yan Shi, Yongli Xu, Ningli Wang
PURPOSE: To evaluate the effectiveness of microcatheter-assisted trabeculotomy (MAT) to treat primary congenital glaucoma (PCG) after failed prior glaucoma surgeries. METHODS: Retrospective, non-comparative, interventional case series conducted at Beijing Tongren Eye Center, China. Outcome measures were compared between three groups: Successful and complete (≥330-degrees) MAT; successful and partial (<330-degrees) MAT; or cases converted to traditional trabeculotomy when Schlemm's canal could not be catheterized >180-degrees...
October 22, 2018: Journal of Glaucoma
Timothy M Janetos, Dustin D French, Jennifer L Beaumont, Angelo P Tanna
PURPOSE: To describe the prescribing patterns of ocular hypotensive medications by ophthalmologists and optometrists in the United States for Medicare beneficiaries. MATERIALS AND METHODS: This cross-sectional observational study examined all Medicare Part D claims of ocular hypotensive medications prescribed by practicing ophthalmologists and optometrists in the United States in 2014. Claims rate was calculated as a function of the total number of Medicare part D beneficiaries within a given region...
October 22, 2018: Journal of Glaucoma
Ramazan Yağcı, Serdar Dervişoğulları, Emre Güler, Yüksel Totan, İbrahim Feyzi Hepşen
PURPOSE: The purpose of the present study was to evaluate the aqueous humor Endocan and Endostatin levels in patients with pseudoexfoliation syndrome (PEX) and to compare the results with healthy individuals. METHODS: 29 cataract patients with PEX syndrome (PEX group) and 32 cataract patients without PEX syndrome (control group) were enrolled in the study. Endocan and Endostatin were measured in the aqueous humor of the PEX and control groups by enzyme-linked immunosorbent assay...
October 18, 2018: Journal of Glaucoma
Ayodeji E Sotimehin, Pradeep Y Ramulu
BACKGROUND: Glaucomatous VF loss can have far-reaching and debilitating consequences on an individual, affecting one's ability to perform many important tasks. Although assessment of glaucoma-related disability constitutes an important part of clinical care, there remains a lack of organized, detailed information on the most suitable methods to capture disability in glaucoma. PURPOSE: This review details the available methods to measure glaucoma-related disability, highlights important findings from studies utilizing these various methods...
October 15, 2018: Journal of Glaucoma
Juan Francisco Santamaría-Álvarez, Juan Lillo-Sopena, Silvia Sanz-Moreno, Josep Maria Caminal-Mitjana
In recent years, minimally-invasive glaucoma surgery has emerged as a novel approach to lowering intraocular pressure (IOP). This technique, which is usually reserved for mild to moderate cases, is less invasive than classic filtration surgery and potentially offers a better safety profile. The XEN Gel Stent is implanted through a minimally-invasive, ab interno procedure to create a subconjunctival pathway. Conjunctival tissue disruption is minimal and flow is restricted to avoid hypotony. Data on the optimal approach to managing complications associated with this procedure are limited due to the relatively recent commercialization of this device...
October 11, 2018: Journal of Glaucoma
Hellen C S Römkens, Henny J M Beckers, Jan S A G Schouten, Rudy M M A Nuijts, Tos T J M Berendschot, Christophe M Breusegem, Carroll A B Webers
No abstract text is available yet for this article.
October 11, 2018: Journal of Glaucoma
Tomomi Higashide, Tsubasa Nishino, Kimikazu Sakaguchi, Yutaro Yamada, Kazuhisa Sugiyama
PURPOSE: To investigate factors associated with decreased corneal endothelial cell density (ECD) after trabeculectomy with mitomycin C (MMC). METHODS: Retrospective review of consecutive glaucoma cases who underwent trabeculectomy with MMC. The types of glaucoma included were primary open angle glaucoma (POAG), exfoliation glaucoma (XFG), neovascular glaucoma (NVG), and uveitic glaucoma (UG). The postoperative ECD changes compared to the preoperative ECD and risk factors for ECD decrease were analyzed using mixed-effects models...
October 11, 2018: Journal of Glaucoma
Raquel Esteves Marques, Nuno Pinto Ferreira, David Cordeiro Sousa, Joana Pinto, André Barata, Paula Sens, Luís Abegão Pinto
PURPOSE: XEN® gel stent is a minimally invasive surgical device aimed at creating a subconjunctival drainage of aqueous humor, thereby reducing intraocular pressure (IOP). Being a novel device, doubts remain regarding the efficacy and safety of its implantation in the early stage of new users. This paper illustrates the XEN® implantation learning curve, assessed through several surgeons of different expertise. METHODS: Retrospective study on the first 6 XEN® implants performed by each of 10 certified ophthalmic surgeons...
October 11, 2018: Journal of Glaucoma
Ji-Hye Park, Chungkwon Yoo
No abstract text is available yet for this article.
October 11, 2018: Journal of Glaucoma
Tarannum Mansoori
No abstract text is available yet for this article.
October 11, 2018: Journal of Glaucoma
Pooja Patel, Alon Harris, Carol Toris, Leslie Tobe, Matthew Lang, Aditya Belamkar, Adrienne Ng, Alice C Verticchio Vercellin, Sunu Mathew, Brent Siesky
Primary open-angle glaucoma (POAG) is a multifactorial optic neuropathy characterized by progressive retinal ganglion cell death and visual field loss. Some speculate that gender plays a role in the risk of developing POAG and that the physiologic differences between men and women may be attributed to the variable effects of sex hormones on intraocular pressure (IOP), ocular blood flow, and/or neuroprotection. Estrogen, in the form of premenopausal status, pregnancy, and post-menopausal hormone therapy is associated with increase in ocular blood flow, decrease in IOP and neuroprotective properties...
October 11, 2018: Journal of Glaucoma
Won Hyuk Oh, Bum Gi Kim, Haksu Kyung, Joo Hwa Lee
PURPOSE: To investigate the prevalence of normal intraocular pressure (IOP) at first visit among patients with primary angle closure glaucoma (PACG) and their ocular characteristics. PATIENTS AND METHODS: We retrospectively reviewed patients with PACG in a referral center. According to untreated IOP, we divided PACG eyes into two groups: those with normal IOP and those with high IOP (>21▒mmHg) at the first visit. RESULTS: One hundred sixty eyes of 160 Korean PACG patients were included...
October 8, 2018: Journal of Glaucoma
Zeynep Aktas, Bektas Caglar, Murat Hasanreisoglu
PURPOSE: To report a case of panscleritis after gonioscopy-assisted transluminal trabeculotomy (GATT). METHODS: We describe the case of a 33-year-old man with a history of unilateral anterior uveitis and glaucoma, who developed panscleritis after GATT surgery. RESULTS: Uneventful GATT surgery was performed in a glaucomatous left eye. On the second postoperative day, the patient developed tenderness on palpation of the eye. Ophthalmic examination revealed significant diffuse hyperemia, elongated and tortuous upper bulbar conjunctival/scleral vessels, and exudative retinal detachment at the superior nasal quadrant, with diffuse scleral thickening...
October 8, 2018: Journal of Glaucoma
Benjamin Penaud, Igor Leleu, Olivier Laplace, Jad Akesbi, Esther Blumen-Ohana, Jean-Philippe Nordmann
PURPOSE: To report on the frequency, efficacy, and safety of laser goniopuncture (LGP) in lowering IOP following mitomycin-C augmented non-penetrating deep sclerectomy (NPDS) in a large cohort of eyes. METHODS: Monocenter database retrospective study. We reviewed records of 350 eyes that underwent NPDS between 2009 and 2015, at National Ophthalmology Center of XV-XX (Paris, France). We recorded incidence of LGP, time between NPDS and LGP, IOP efficacy and the occurrence of complications...
October 8, 2018: Journal of Glaucoma
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