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European Journal of Cancer Prevention

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https://www.readbyqxmd.com/read/28125434/vitamin-d-status-and-risk-for-malignant-cutaneous-melanoma-recent-advances
#1
Maria N Ombra, Panagiotis Paliogiannis, Valentina Doneddu, Maria C Sini, Maria Colombino, Carla Rozzo, Ignazio Stanganelli, Francesco Tanda, Antonio Cossu, Giuseppe Palmieri
Cutaneous malignant melanoma, whose incidence is increasing steadily worldwide, is the result of complex interactions between individual genetic factors and environmental risk factors. Ultraviolet radiation represents the most important environmental risk factor for the development of skin cancers, including melanoma. Sun exposure and early sunburn during childhood are the principal causes of cutaneous melanoma insurgence in adults, with double the risk relative to a nonexposed population. Consequently, ultraviolet protection has long been recognized as an important measure to prevent such a malignancy...
January 25, 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/28118209/menstrual-and-reproductive-factors-in-the-risk-of-thyroid-cancer-in-japanese-women-the-japan-public-health-center-based-prospective-study
#2
Sangah Shin, Norie Sawada, Eiko Saito, Taiki Yamaji, Motoki Iwasaki, Taichi Shimazu, Shizuka Sasazuki, Manami Inoue, Shoichiro Tsugane
The aim of this study was to evaluate the associations between menstrual and reproductive factors and thyroid cancer risk among Japanese women. A total 54 776 women aged 40-69 years completed a self-administered questionnaire, which included menstrual and reproductive history. During 1990-2012, 187 newly diagnosed cases of thyroid cancer were identified. Hazard ratios (HRs) and 95% confidence intervals (CIs) for menstrual and reproductive factors and incidence of thyroid cancer were estimated using Cox proportional hazards regression...
January 21, 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/28079603/genital-use-of-talc-and-risk-of-ovarian-cancer-a-meta-analysis
#3
Wera Berge, Kenneth Mundt, Hung Luu, Paolo Boffetta
Some epidemiological studies suggest an association between genital use of talc powders and increased risk of ovarian cancer, but the evidence is not consistent. We performed a meta-analysis of epidemiological studies to formally evaluate this suspected association. A systematic search was conducted in Medline, Embase, and Scopus, leading to the identification of 24 case-control studies and three cohort studies, including 302 705 women with ovarian cancer. In the meta-analysis, we used a random-effect model to calculate summary estimates of the association between genital use of talc and occurrence of ovarian cancer...
January 11, 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/28059857/risk-for-cancer-among-people-living-with-aids-1997-2012-the-s%C3%A3-o-paulo-aids-cancer-linkage-study
#4
Luana F Tanaka, Maria R D O Latorre, Eliana B Gutierrez, Maria P Curado, Guenter Froeschl, Christian Heumann, Karl-Heinz Herbinger
Previous studies have reported an increased risk for certain types of cancer in the HIV-infected population. The aim of this study was to assess the risk for cancer in people with AIDS (PWA) in comparison with the general population in São Paulo (Brazil), between 1997 and 2012. A population-based registry linkage study was carried out to assess the risk for cancer, using a standardized incidence ratio (SIR) approach. A total of 480 102 person-years, of which 337 941 (70.4%) person-years were men, were included in the analysis...
January 4, 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/28059856/lack-of-correlation-between-x-ray-repair-cross-complementing-group-1-gene-polymorphisms-and-the-susceptibility-to-colorectal-cancer-in-a-malaysian-cohort
#5
Tze-Pheng Lau, Lay-Hoong Lian, Phaik-Leng Cheah, Lai-Meng Looi, April C Roslani, Khean-Lee Goh, Ping-Chin Lee, Kek-Heng Chua
X-ray repair cross-complementing group 1 (XRCC1) is one of the key components in the base excision repair pathway that repairs erroneous DNA lesions and removes nonbulky base adducts for the maintenance of genome integrity. Studies have revealed that differences in individual DNA repair capacity can impact the interindividual variation in cancer susceptibility, tumour aggressiveness and treatment response. The relationship between XRCC1 and sporadic colorectal cancer (CRC) susceptibility, which is hitherto inconclusive, has been explored in many association studies of different populations...
January 4, 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/27926538/effect-of-spirogyra-neglecta-on-the-early-stages-of-1-2-dimethylhydrazine-induced-colon-carcinogenesis-in-rats
#6
Sirinya Taya, Tarika Thumvijit, Teera Chewonarin, Charatda Punvittayagul, Rawiwan Wongpoomchai
This study focused on the chemopreventive effects of Spirogyra neglecta extract (SNE) and dried S. neglecta mixed diet on the early stages of 1,2-dimethylhydrazine (DMH)-induced colon carcinogenesis in rats. Male Wistar rats were injected with DMH to initiate aberrant crypt foci (ACF) formation. In the initiation stage, SNE significantly decreased the number of ACF in the colon of DMH-treated rats. Rats that received a low dose of SNE showed enhanced activity of several detoxifying and antioxidant enzymes. In the postinitiation stage, a low dose of SNE significantly decreased the number of ACF in the colon of DMH-treated rats...
December 6, 2016: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/27902644/coffee-consumption-and-risk-of-nonmelanoma-skin-cancer-a-dose-response-meta-analysis
#7
Golnaz Vaseghi, Shaghayegh Haghjoo-Javanmard, Jamal Naderi, Azadeh Eshraghi, Manijeh Mahdavi, Marjan Mansourian
Several epidemiological studies have evaluated the associations between coffee consumption and the risk of skin cancer; however, the results were not conclusive. This systematic review and meta-analysis of the cohort and case-control studies was carried out to determine the association between coffee intake and the risk of nonmelanoma skin cancer. Studies were identified by searching the PubMed and MEDLINE databases (to November 2015). Study-specific risk estimates were pooled under the random-effects model...
November 29, 2016: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/28107223/response-to-the-letter-to-the-editor-by-weberpals-et-al-on-our-article-entitled-%C3%AE-blocker-use-and-mortality-in-cancer-patients-systematic-review-and-meta-analysis-of-observational-studies
#8
Shanliang Zhong, Jianhua Zhao
No abstract text is available yet for this article.
March 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/27622768/the-rad51c-exonic-splice-site-mutations-c-404g-c-and-c-404g-t-are-associated-with-familial-breast-and-ovarian-cancer
#9
Guido Neidhardt, Alexandra Becker, Jan Hauke, Judit Horváth, Nadja Bogdanova Markov, Stefanie Heilmann-Heimbach, Heide Hellebrand, Holger Thiele, Janine Altmüller, Peter Nürnberg, Alfons Meindl, Kerstin Rhiem, Britta Blümcke, Barbara Wappenschmidt, Rita K Schmutzler, Eric Hahnen
Whereas RAD51C mutations increase the relative risk for ovarian cancer (OC) to 5.88 (95% confidence interval=2.91-11.88, P=7.65×10), the associated risks for breast cancer (BC) remain largely unknown, as deleterious RAD51C alterations are extremely rare in BC-only families. Here, we report the results of a RAD51C mutational screening in a large series of German familial index patients negative for pathogenic BRCA1/2 mutations and the in-vitro characterization of two novel exonic RAD51C splice-site mutations...
March 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/27222937/determination-of-amino-acids-in-urine-of-patients-with-prostate-cancer-and-benign-prostate-growth
#10
Wiktor D Sroka, Berin A Boughton, Priyanka Reddy, Ute Roessner, Piotr Słupski, Piotr Jarzemski, Anita Dąbrowska, Michał J Markuszewski, Michał P Marszałł
Prostate cancer is the leading type of cancer diagnosed in men. Serum prostate-specific antigen levels and digital rectal exam are far from perfect when it comes to differentiation of patients with prostate cancer and benign prostatic hyperplasia. In this study, we attempt to determine whether amino acids can be used as prostate cancer biomarkers. Concentrations of derivatized amino acids and amines were quantified by liquid chromatography tandem mass spectrometry. A total of 100 urine samples from the two groups including samples provided before and after prostate massage were examined quantitatively for amino acid and amine concentrations with 50 urine samples collected from cancer patients and 50 samples from patients diagnosed with benign prostatic hyperplasia...
March 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/27014938/worldwide-incidence-mortality-and-time-trends-for-cancer-of-the-oesophagus
#11
Bhawna Gupta, Narinder Kumar
The incidence and mortality trends of oesophageal cancer are changing significantly across the world with considerable heterogeneity between sex, histological types, ethnic patterns and geographical distribution. Recent oesophageal cancer incidence and mortality trends have been analysed using data available from the WHO mortality database, the GLOBOCAN 2012 database and the Cancer Incidence in Five Continents database managed by the International Agency for Research on Cancer. Huge geographical variation is an epidemiological characteristic of oesophageal cancer, with the highest incidence rates observed in Eastern Asia and in Eastern and Southern Africa and the lowest rates observed in Western Africa...
March 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/27010329/awareness-of-human-papillomavirus-after-introduction-of-hpv-vaccination-a-large-population-based-survey-of-scandinavian-women
#12
Louise T Thomsen, Mari Nygård, Signe Stensen, Bo Terning Hansen, Lisen Arnheim Dahlström, Kai-Li Liaw, Christian Munk, Susanne K Kjaer
Using a large, population-based survey, we assessed the levels and correlates of human papillomavirus (HPV) awareness among Scandinavian women after introduction of HPV vaccination. In 2011-2012, a random sample of women aged between 18 and 45 years from Denmark, Sweden and Norway received a questionnaire on lifestyle, health and HPV awareness. We included 47 895 women (response rate 60.6%) in our study. Country-specific and age-specific proportions of women who had heard of HPV in 2011-2012 (postvaccination survey) were compared with corresponding proportions in an identical survey from 2004-2005 (prevaccination survey, n=54 079, response rate 71...
March 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/26909566/bart-mirnas-an-unimaginable-force-in-the-development-of-nasopharyngeal-carcinoma
#13
Youhong Wang, Zhen Guo, Yan Shu, Honghao Zhou, Hui Wang, Wei Zhang
Nasopharyngeal carcinoma (NPC) is a head and neck cancer that represents a major health burden in Southern China and Southeast Asia. Although the close association of NPC with Epstein-Barr virus (EBV) infection has been demonstrated, its exact role in the pathogenesis of this malignancy is still unclear. The expression of EBV-encoded microRNAs, especially BART miRNAs, which are encoded from the BamHI-A region of the viral genome, is detected at a high level in NPC. miRNAs are small noncoding mRNAs that can positively regulate the virus to ensure accurate expression of viral genomes and to modify the gene expression of host cells by negative regulation...
March 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/26908154/prepregnancy-obesity-a-risk-factor-for-future-development-of-ovarian-and-breast-cancer
#14
Roy Kessous, Ehud Davidson, Mihai Meirovitz, Ruslan Sergienko, Eyal Sheiner
The aim of this study was to investigate the association between a history of prepregnancy obesity and a woman's future long-term risk for the development of female malignancies. A population-based study compared the incidence of long-term female malignancies in a cohort of consecutive women with and without a diagnosis of prepregnancy obesity. Deliveries occurred between the years 1988 and 2013, with a mean follow-up duration of 11.6 years. Women with known malignancies before the index pregnancy and known genetic predisposition for malignancy were excluded from the study...
March 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/26895574/trends-in-thyroid-cancer-incidence-and-mortality-in-portugal
#15
Luís Raposo, Samantha Morais, Maria J Oliveira, Ana P Marques, Maria José Bento, Nuno Lunet
The objective was to quantify thyroid cancer incidence and mortality trends in Portugal. The number of thyroid cancer cases and incidence rates were retrieved from the Regional Cancer Registries for the period 1989-2011. The number of deaths and mortality rates were obtained from the WHO cancer mortality database (1988-2003 and 2007-2012) and Statistics Portugal (2004-2006; 1988-2012 by region). Joinpoint regression of the standardized incidence and mortality rates was performed. A significant, rapid and continued increase in incidence was observed for both sexes in each of the Regional Cancer Registries, with annual per cent changes (APCs) ranging between 2 and 9...
March 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/26890987/serial-measurement-of-type-specific-human-papillomavirus-load-enables-classification-of-cervical-intraepithelial-neoplasia-lesions-according-to-occurring-human-papillomavirus-induced-pathway
#16
Stefanie Verhelst, Willy A J Poppe, Johannes J Bogers, Christophe E Depuydt
This retrospective study examined whether human papillomavirus (HPV) type-specific viral load changes measured in two or three serial cervical smears are predictive for the natural evolution of HPV infections and correlate with histological grades of cervical intraepithelial neoplasia (CIN), allowing triage of HPV-positive women. A cervical histology database was used to select consecutive women with biopsy-proven CIN in 2012 who had at least two liquid-based cytology samples before the diagnosis of CIN. Before performing cytology, 18 different quantitative PCRs allowed HPV type-specific viral load measurement...
March 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/26886238/associations-of-alcohol-use-disorders-with-esophageal-and-gastric-cancers-a-population-based-study-in-sweden
#17
Jianguang Ji, Jan Sundquist, Kristina Sundquist
Alcohol consumption is associated with squamous cell carcinoma of the esophagus, but little is known about whether alcohol consumption is associated with adenocarcinoma of the esophagus and gastric cancer, which we attempt to clarify in this study. Individuals with alcohol use disorders were identified from the nation-wide Swedish Hospital Discharge Register and Outpatient Register, the Crime Register, and the Prescription Drug Register, and they were linked to the Swedish Cancer Registry to calculate standardized incidence ratios of esophageal and gastric cancers using those without alcohol use disorders (AUDs) as a reference...
March 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/26882077/the-association-between-coffee-consumption-and-bladder-cancer-incidence-in-a-pooled-analysis-of-the-miyagi-cohort-study-and-ohsaki-cohort-study
#18
Kemmyo Sugiyama, Yumi Sugawara, Yasutake Tomata, Yoshikazu Nishino, Akira Fukao, Ichiro Tsuji
Recent epidemiological studies of the association between coffee consumption and the risk of bladder cancer have yielded conflicting results. The aim of the present study was to examine the association between coffee consumption and the incidence of bladder cancer on the basis of pooled data from two cohort studies carried out in Miyagi Prefecture, northeastern Japan. We delivered self-administered questionnaires inquiring about the frequency of coffee consumption and other lifestyle factors in 1990 for the Miyagi Cohort Study and in 1994 for the Ohsaki Cohort Study...
March 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/28005615/trends-in-net-survival-from-kidney-cancer-in-six-european-latin-countries-results-from-the-sudcan-population-based-study
#19
Lucia Mangone, Nadine Bossard, Rafael Marcos-Gragera, Annamaria Pezzarossi, Francesca Roncaglia, Paolo Giorgi Rossi
Kidney cancer is a frequent malignant disease. To date, there is no evidence on the effectiveness of early detection and, in most cases, surgery represents the only standard treatment. So far, there is no standardized therapy for localized and locally advanced renal tumors; however, the recent introduction of target therapy has significantly improved the prognosis of metastatic disease. Therefore, survival differences in Europe are deemed to involve differences in diagnostic and therapeutic approaches. The aim of the SUDCAN collaborative study was to compare the net survival from kidney cancer between six European Latin countries (Belgium, France, Italy, Portugal, Spain, and Switzerland) and provide trends in net survival and dynamics of excess mortality rates up to 5 years after diagnosis...
January 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/28005614/trends-in-net-survival-from-prostate-cancer-in-six-european-latin-countries-results-from-the-sudcan-population-based-study
#20
Pascale Grosclaude, Laurent Roche, Rafael Fuentes-Raspall, Nerea Larrañaga
Cancer survival is a key measure of the effectiveness of a health-care system. European Latin countries have some differences in their health system; therefore, it is of interest to compare them in terms of survival from cancer. Prostate cancer data from six countries (Belgium, France, Italy, Portugal, Spain, and Switzerland) were extracted from the EUROCARE-5 database (end of follow-up: 1 January 2009). First, the net survival (NS) was studied over the 2000-2004 period using the Pohar-Perme estimator. For trend analyses, the study period was specific to each country...
January 2017: European Journal of Cancer Prevention
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