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European Journal of Cancer Prevention

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https://www.readbyqxmd.com/read/29215374/empirically-derived-dietary-patterns-and-ovarian-cancer-risk-a-meta-analysis
#1
Hai-Fang Wang, Ai-Lin Yao, Yan-Yan Sun, Ai-Hua Zhang
Dietary patterns, which reflect overall diet and possible nutrient and food interactions, have been reported to be related to ovarian cancer (OC) risk. However, studies on the relationship between dietary patterns and OC risk have been inconsistent. Thus, we carried out a systematic meta-analysis to assess the relationship between dietary patterns and the risk of OC. Relevant studies are identified by searching the Medline and Embase electronic databases up to December 2016. The Cochrane Q statistic and the I statistical were used to evaluate heterogeneity...
December 5, 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/29194280/conization-and-healthcare-use-a-population-based-register-study
#2
Maria E Frederiksen, Miguel Vázquez-Prada Baillet, Pernille T Jensen, Carsten Rygaard, Jesper Hallas, Elsebeth Lynge
The aim of this study was to assess whether negative psychological consequences of conization reported in questionnaire studies translated into increased use of the healthcare services that could relieve such symptoms. This was a population-based register study comparing women undergoing conization with a control group of women with normal cytology results. Data were derived from Danish registers. Using the difference-in-differences method, we measured contacts with general practitioners (GPs), hospitals, psychiatrist/psychologists, and use of anxiolytic and antidepressant prescription drugs over 5 years 'before' and 'after' the conization in the study group, and in comparable periods in the control group...
November 29, 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/29176350/low-participation-in-organized-colorectal-cancer-screening-in-france-underlying-ethical-issues
#3
Grégoire Moutel, Nathalie Duchange, Astrid Lièvre, Marie Brigitte Orgerie, Odile Jullian, Hélène Sancho-Garnier, Sylviane Darquy
International studies have shown a significant reduction in colorectal cancer (CRC) mortality following the implementation of organized screening programs, given a sufficient participation rate and adequate follow-up. The French national CRC screening program has been generalized since 2008 and targets 18 million men and women aged 50-74 years. Despite broad recommendations, the participation rate remains low (29.8%), questioning the efficiency of the program. A panel of experts was appointed by the French National Cancer Institute to critically examine the place of autonomy and efficiency in CRC screening and propose recommendations...
November 24, 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/29135538/cervical-morbidity-in-alsace-france-results-from-a-regional-organized-cervical-cancer-screening-program
#4
Jean-Jacques Baldauf, Muriel Fender, Christine Bergeron, Emilie Marrer, Michel Velten, Pierre Pradat, Marc Arbyn
In 1994, a pilot program of cervical cancer screening was introduced in the Alsace region, France. Women aged 25-65 years were proposed to have one Pap smear every 3 years. The objective was to assess cervical morbidity in Alsace before the human papillomavirus vaccinated population reaches the age of screening. Data on cervical lesions and cancers were collected by EVE for the period September 2008 to August 2011 from existing medical services and cytopathology laboratories in Alsace. Cytological and histological data were completed with data from the two cancer registries covering the region (Bas-Rhin and Haut-Rhin)...
November 13, 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/27552246/on-the-international-agency-for-research-on-cancer-classification-of-glyphosate-as-a-probable-human-carcinogen
#5
Robert E Tarone
The recent classification by International Agency for Research on Cancer (IARC) of the herbicide glyphosate as a probable human carcinogen has generated considerable discussion. The classification is at variance with evaluations of the carcinogenic potential of glyphosate by several national and international regulatory bodies. The basis for the IARC classification is examined under the assumptions that the IARC criteria are reasonable and that the body of scientific studies determined by IARC staff to be relevant to the evaluation of glyphosate by the Monograph Working Group is sufficiently complete...
November 8, 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/29111981/the-detection-of-interval-colorectal-cancers-following-screening-by-fecal-immunochemical-test-may-predict-worse-outcomes-and-prompt-ethical-concerns-a-6-year-population-based-cohort-study-in-a-full-district
#6
Corrado R Asteria, Giuseppe Lucchini, Linda Guarda, Paolo Ricci, Mauro Pagani, Luigi Boccia
The rates of colorectal cancer (CRC) interval surveyed in screen-detected patients using a fecal immunochemical test (FIT) are not negligible. The aim of this study was to assess the effect of interval cancer on outcomes compared with a population with cancer diagnosed after a positive test result. All patients between 50 and 71 years of age, who were residents of the Mantua district, affected by CRC and operated on from 2005 to 2010 were reviewed. Other than patient-related, disease-related, and treatment-related factors and tumor location, this population was differentiated as either participating or not to screening and then into populations developing interval cancer after a negative FIT result...
November 3, 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/29084019/expression-of-klf6-sv2-in-colorectal-cancer-and-its-impact-on-proliferation-and-apoptosis
#7
Biao Zhang, Dan-Dan Guo, Jia-Ying Zheng, Yan-An Wu
Kruppel like factor 6 (KLF6), a member of KLF family, which has classic zinc finger structure, is broadly considered to have anticancer activity. The role of SV2 variant, one of KLF6 alternative splicing isoforms has not yet been definite in the colorectal cancer. This study aimed to detect the expression of the KLF6-SV2 in colorectal cancer and investigate its impact on cell proliferation and apoptosis. qRT-PCR was used to quantitatively determine KLF6-SV2 mRNA expression in colorectal cancer samples, corresponding normal tissue, normal colonic mucosal cell line FHC and seven colorectal cancer cell lines...
October 27, 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/29064839/sex-differences-in-the-association-between-a-previous-cancer-diagnosis-and-the-use-of-medication
#8
Ana Rute Costa, Luís Pacheco-Figueiredo, Luís Alves, Nuno Lunet
We aimed to quantify the association between a previous cancer diagnosis and medication use, depicting possible sex differences. We analysed data from a representative sample of the Portuguese adult population (n=32 610), which was collected through face-to-face interviews, using a structured questionnaire. The effect of a previous diagnosis of cancer was quantified through prevalence ratios (PR), adjusted for age, education and region of residence. Cancer survivors (CS) reported higher use of prescribed medication, with greater adjusted PR among men (1...
October 23, 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/28957821/association-between-mammographic-density-and-tumor-marker-defined-breast-cancer-subtypes-a-case-control-study
#9
Jinyoung Shin, Jeong Eon Lee, Hyeon Young Ko, Tuong Linh Nguyen, Seok Jin Nam, John Llewelyn Hopper, Yun-Mi Song
High mammographic density (MD) is the most important risk factor for breast cancer. This study aimed to clarify the relationship between MD and breast cancer subtypes defined by tumor markers. We enrolled 642 women with breast cancer (69% premenopausal) and 1241 controls matched for age and menopausal status. Absolute mammographic dense area (ADA), percent mammographic dense area (PDA), and nondense area were assessed using a computer-assisted thresholding technique. We classified breast cancer cases into four subtypes using information on tumor marker expression such as estrogen receptor (ER), progesterone receptor (PR), and Cerb2 receptor (HER2); luminal A (ER+ and/or PR+, HER2-), luminal B (ER+ and/or PR+, HER2+), HER2-overexpressing (ER-, PR-, and HER2+), and triple-negative (ER-, PR-, and HER2-)...
September 27, 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/28957847/the-cancer-moonshot-task-force-should-focus-more-on-prevention
#10
Devan Hawkins
No abstract text is available yet for this article.
November 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/28598889/survival-of-solid-cancer-patients-in-france-1989-2013-a-population-based-study
#11
Anne Cowppli-Bony, Zoé Uhry, Laurent Remontet, Nicolas Voirin, Anne-Valérie Guizard, Brigitte Trétarre, Anne-Marie Bouvier, Marc Colonna, Nadine Bossard, Anne-Sophie Woronoff, Pascale Grosclaude
This study provides updates of net survival (NS) estimates at 5, 10, and 15 years as well as survival trends for 35 solid cancers in France using data from 19 population-based cancer registries. The study considered all cases of solid cancer diagnosed between 1989 and 2010 in patients older than 15 years of age who were actively followed up until 30 June 2013. NS was estimated using the Pohar-Perme method. The age-standardized NS used the international cancer survival standard weights. The 5-year age-standardized NSs ranged from 4% (pleural mesothelioma) to 93% (prostate) in men and from 10% (pancreas) to 97% (thyroid) in women...
November 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/28542079/adherence-to-mediterranean-diet-and-risk-of-gastric-cancer-results-of-a-case-control-study-in-italy
#12
Jovana Stojanovic, Luca Giraldi, Dario Arzani, Roberta Pastorino, Alberto Biondi, Roberto Persiani, Stefania Boccia, Emanuele Leoncini
The aim of this study is to evaluate the association between adherence to Mediterranean diet (MD) and gastric cancer (GC). A case-control study was carried out at the Fondazione Policlinico 'A. Gemelli' (Rome, Italy) from 2003 to 2015. A total of 223 incident cases and 223 controls were interviewed. Dietary intake was assessed through a validated food frequency questionnaire that collected information on more than 25 food items. The association between adherence to MD and risk of GC was quantified by calculating Odds Ratios (OR) and 95% confidence intervals (CI)...
November 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/28542077/physical-activity-sedentary-time-and-risk-of-colorectal-cancer-the-singapore-chinese-health-study
#13
Yvonne L Eaglehouse, Woon-Puay Koh, Renwei Wang, Jin Aizhen, Jian-Min Yuan, Lesley M Butler
Singapore has experienced a marked increase in colorectal cancer incidence over the past 40 years. Evidence from prospective studies in Western Europe and the USA suggests that low physical activity and high amounts of sedentary time are associated with increased colorectal cancer risk. The aim of this study is to evaluate these relationships in an Asian population. The Singapore Chinese Health Study enrolled 63 257 adults between 1993 and 1998. At enrollment, participants reported past year physical activity and time spent sitting...
November 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/28538040/interleukin-10-592c-a-but-not-1082a-g-promoter-single-nucleotide-polymorphism-is-associated-with-a-decreased-risk-of-colorectal-cancer-in-an-ethnic-kashmiri-population-a-case-control-study
#14
Mujeeb Z Banday, Aga S Sameer, Nissar A Chowdri, Ehtishamul Haq
Chronic inflammation influences the development of various cancers including colorectal cancer (CRC). Interleukin-10 (IL-10), an anti-inflammatory cytokine, plays a vital role in several homeostatic physiological processes occurring in the human gastrointestinal tract including intestinal inflammation and is a key regulator of several gastrointestinal tract pathophysiological processes such as inflammatory bowel diseases that are associated with an increased predisposition to CRC. Several studies have reported the association of various polymorphisms in the human IL-10 gene including IL-10 -592C/A and IL-10 -1082A/G single nucleotide polymorphisms (SNPs) with various cancers including CRC, but these SNPs are yet to be studied in a Kashmiri population with respect to CRC risk...
November 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/28125434/vitamin-d-status-and-risk-for-malignant-cutaneous-melanoma-recent-advances
#15
Maria N Ombra, Panagiotis Paliogiannis, Valentina Doneddu, Maria C Sini, Maria Colombino, Carla Rozzo, Ignazio Stanganelli, Francesco Tanda, Antonio Cossu, Giuseppe Palmieri
Cutaneous malignant melanoma, whose incidence is increasing steadily worldwide, is the result of complex interactions between individual genetic factors and environmental risk factors. Ultraviolet radiation represents the most important environmental risk factor for the development of skin cancers, including melanoma. Sun exposure and early sunburn during childhood are the principal causes of cutaneous melanoma insurgence in adults, with double the risk relative to a nonexposed population. Consequently, ultraviolet protection has long been recognized as an important measure to prevent such a malignancy...
November 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/28059856/lack-of-correlation-between-x-ray-repair-cross-complementing-group-1-gene-polymorphisms-and-the-susceptibility-to-colorectal-cancer-in-a-malaysian-cohort
#16
Tze-Pheng Lau, Lay-Hoong Lian, Phaik-Leng Cheah, Lai-Meng Looi, April C Roslani, Khean-Lee Goh, Ping-Chin Lee, Kek-Heng Chua
X-ray repair cross-complementing group 1 (XRCC1) is one of the key components in the base excision repair pathway that repairs erroneous DNA lesions and removes nonbulky base adducts for the maintenance of genome integrity. Studies have revealed that differences in individual DNA repair capacity can impact the interindividual variation in cancer susceptibility, tumour aggressiveness and treatment response. The relationship between XRCC1 and sporadic colorectal cancer (CRC) susceptibility, which is hitherto inconclusive, has been explored in many association studies of different populations...
November 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/27768609/long-chain-%C3%AF-6-plasma-phospholipid-polyunsaturated-fatty-acids-and-association-with-colon-adenomas-in-adult-men-a-cross-sectional-study
#17
Charles A Pickens, Mariana de Fátima Albuquerque Pereira, Jenifer I Fenton
Dietary lipid intake can be associated with an increased risk for colorectal cancer depending on its composition. Carcinogenesis alters lipid metabolism to facilitate cell growth and survival. For instance, metabolites of polyunsaturated fatty acids (PUFAs) are associated with increasing colon cell proliferation. Moreover, precancerous colon lesions (i.e. adenomas) increase the risk for colorectal cancer. In this study, we investigated associations between plasma PUFAs and the number of colon polyps and polyp type (i...
November 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/27749381/differences-in-cervical-cancer-screening-between-immigrants-and-nonimmigrants-in-norway-a-primary-healthcare-register-based-study
#18
Kathy A Møen, Bernadette Kumar, Samera Qureshi, Esperanza Diaz
The prevalence of cervical cancer is high among some groups of immigrants. Although there is evidence of low participation in cervical cancer screening programs among immigrants, studies have been subject to selection bias and accounted for few immigrant groups. The aim of this study was to compare the proportion of several groups of immigrants versus nonimmigrants attending the cervical cancer-screening program in Norway. In addition, we aimed to study predictors for attendance to the screening program. Register-based study using merged data from four national registries...
November 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/27571214/adiposity-breast-density-and-breast-cancer-risk-epidemiological-and-biological-considerations
#19
Ludivine Soguel, Francine Durocher, André Tchernof, Caroline Diorio
Excess total body fat and abdominal adipose tissue are recognized risk factors for metabolic diseases but also for some types of cancers, including breast cancer. Several biological mechanisms in connection with local and systemic effects of adiposity are believed to be implicated in breast cancer development, and may involve breast fat. Breast adipose tissue can be studied through mammography by looking at breast density features such as the nondense area mainly composed of fat, or the percent breast density, which is the proportion of fibroglandular tissue in relation to fat...
November 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/27128581/a-prospective-cohort-study-on-dietary-acrylamide-intake-and-the-risk-for-cutaneous-malignant-melanoma
#20
Nadezda Lipunova, Leo J Schouten, Piet A van den Brandt, Janneke G F Hogervorst
Epidemiological studies have shown inconsistent associations between dietary acrylamide exposure and the risk for various malignancies. This is the first epidemiological study on the association between acrylamide intake and the risk for cutaneous malignant melanoma (CMM). A case-cohort analysis was carried out within the prospective Netherlands Cohort Study on diet and cancer. Acrylamide intake was estimated from a food frequency questionnaire combined with acrylamide data for Dutch foods. After 17.3 years of follow-up, 501 microscopically confirmed cases of CMM were identified...
November 2017: European Journal of Cancer Prevention
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