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European Journal of Cancer Prevention

Yue Wang, Long-Fei Xie, Jie Lin
The association between gallstones or cholecystectomy and the incidence risk of liver cancer is controversial. This is a meta-analysis of observational studies on the role of gallstones or cholecystectomy in primary liver cancer. Relevant studies were identified after the literature search via electronic databases until June 2014. A random-effects model was used to generate pooled multivariable adjusted odds ratios (ORs) and 95% confidence intervals (CIs). Heterogeneity among studies was evaluated using Cochran's Q and I statistics...
May 5, 2018: European Journal of Cancer Prevention
Hélène Willem, Valérie Jooste, Olayide Boussari, Gaëlle Romain, Anne-Marie Bouvier
Staging is essential for scientific exchanges on colorectal cancer. Lack of a consensual definition for synchronous and metachronous metastases for colorectal cancer may introduce artifactual differences between epidemiological studies according to stage. We investigated how variations in the cutoff for the definition of synchronous metastases influenced the stage-specific distribution and incidence and the survival of stage IV patients. Between 2007 and 2013, a total of 4636 cases of colorectal adenocarcinoma were registered in the cancer registry of Burgundy...
May 5, 2018: European Journal of Cancer Prevention
Xiao-Yan Huang, Chao Hu
No abstract text is available yet for this article.
April 23, 2018: European Journal of Cancer Prevention
Wu-Xia Luo, Ye Chen, Yun-Tao Li, Jie Tang, Jing Ding, Yang Du, Qiang Wu, Ji-Yan Liu
For treatment of metastatic colorectal cancer, the dynamics of tumor growth is an important factor for treatment decision. However, it is difficult to evaluate the dynamics of tumor growth, especially those of synchronous metastatic diseases. This study aimed to find some indicators related to tumor proliferation to judge the dynamics of tumor progression. The pathological reports and clinical data of 1205 patients with metastatic colorectal cancer were retrospectively reviewed; 75 patients with known relapse time after radical resection were included, and the expression of proliferation-associated proteins was detected by immunohistochemistry...
April 23, 2018: European Journal of Cancer Prevention
Karla Geiss, Martin Meyer
Population-based cancer registries allow the assessment of regional differences in cancer burden. Comparative cancer statistics are usually reported as ranked bar charts and choropleth maps, which can lead to misinterpretations of the presented figures. The aim of the present study is a regional comparison of cancer statistics in Germany on the level of federal states using funnel plots. Population-based cancer registry data on incidence, mortality, and survival on the level of federal states for the year 2011 were used...
April 18, 2018: European Journal of Cancer Prevention
Asuka Kawachi, Taichi Shimazu, Sanjeev Budhathoki, Norie Sawada, Taiki Yamaji, Motoki Iwasaki, Manami Inoue, Shoichiro Tsugane
Evidence on the association between BMI, height, and endometrial cancer risk, including by subtypes, among Asian populations remains limited. We evaluated the impact of BMI and height on the risk of endometrial cancer, overall and by histological subtype. We prospectively investigated 53 651 Japanese women aged 40-69 years. With an average follow-up duration of 18.6 years, 180 newly diagnosed endometrial cancers were reported, including 119 type 1 and 21 type 2. The association between BMI, height, and endometrial cancer risk was assessed using a Cox proportional hazards regression model with adjustment for potential confounders...
April 18, 2018: European Journal of Cancer Prevention
Samantha Morais, Clara Castro, Luís Antunes, Bárbara Peleteiro, Maria J Bento, Nuno Lunet
To quantify the association between prediagnosis lifestyles with the risk of second primary cancers (SPCs) and survival of patients with gastric first primary cancer (FPC). We recruited 574 gastric patients from two major public hospitals in North Portugal (2001-2006). Smoking, alcohol and dietary habits in the year before FPC diagnosis were evaluated. Patients were followed up to 31 December 2011 for an SPC and to 31 May 2017 for vital status. Cox proportional hazards regression was used to estimate adjusted hazard ratios for incidence of an SPC or death...
April 17, 2018: European Journal of Cancer Prevention
Samuel R Claudio, Bianca A Handan, Carolina F Gomes de Moura, Milena de Barros Viana, Liria Y Yamauchi, Odair Aguiar, Celina T F Oshima, Daniel A Ribeiro
Since its discovery as an antimicrobial agent, fluoride has been used in the control of dental caries. Many studies have shown that the chronic exposure of fluoride in high concentrations causes adverse effects in multiple organs; the use of bioactive compounds present in foods as a tool to mitigate the effects of fluoride could potentially be useful for populations in different parts of the world are exposed to fluoride in a chronic and systemic way. Thus, the aim of this comprehensive review is to present and discuss the published papers that focused on the use of polyphenols and nonpolyphenols that can mitigate the harmful activities promoted by fluoride exposure...
April 17, 2018: European Journal of Cancer Prevention
Leolin Katsidzira, Innocent T Gangaidzo, Rudo Makunike-Mutasa, Tadios Manyanga, Zvifadzo Matsena-Zingoni, Sandie Thomson, Jonathan A Matenga, Simbarashe Rusakaniko, Raj Ramesar
The interplay between hereditary and environmental factors in the causation of colorectal cancer in sub-Saharan Africa is poorly understood. We carried out a community based case-control study to identify the risk factors associated with colorectal cancer in Zimbabwe. We recruited 101 cases of colorectal cancer and 202 controls, matched for age, sex and domicile. Potential risk factors including family history, socioeconomic status, urbanization, diabetes mellitus and previous schistosomiasis were evaluated...
April 11, 2018: European Journal of Cancer Prevention
Nader Parsa, Samira Taravatmanesh, Maurizio Trevisan
Although a large number of studies have shown the associations of high plasma lipid profile levels with cancer, few studies demonstrate the association between low serum cholesterol (<160 mg/dl) and risk for cancer mortality. The aim of this study was to determine the association of low serum cholesterol level as a risk factor for mortality in cancer. The prospective cohort studies were conducted on 19 of 52 cohort studies including 30 179 male and 26 005 female participants who were followed up for 9 years...
April 10, 2018: European Journal of Cancer Prevention
Anita L Iyer, M Kate Bundorf, Dorte Gyrd-Hansen, Jeremy D Goldhaber-Fiebert, Pascale-Renée Cyr, Ivar Sønbø Kristiansen
Cervical cancer (CC) is the 13th most frequent cancer among women in Norway, but the third most common among women aged 25-49 years. The national screening program sends information letters to promote screening participation. We aimed to evaluate how women's stated intention to participate in screening and pursue treatment changed with the provision of additional information on harms associated with screening, and to assess women's preferences on the timing and source of such information. We administered a web-based questionnaire to a panel of Norwegian women aged 25-69 years and randomized into three groups on the basis of when in the screening process additional information was introduced: (i) invited for routine screening, (ii) recommended an additional test following detection of cellular abnormalities, and (iii) recommended precancer treatment...
March 27, 2018: European Journal of Cancer Prevention
Giovanni Corso, Debora Macis, Bernardo Bonanni, Viviana Galimberti
No abstract text is available yet for this article.
March 21, 2018: European Journal of Cancer Prevention
Yingchun Ni, Jinge Du, Xiaolin Yin, Ming Lu
The dose-response relationship between folate and the risk of esophageal cancer (EC) is not clear. To further elucidate their relationships, we carried out a dose-response meta-analysis of folate intake, serum folate, and the risk of EC. PubMed, Embase, Web of Science, and China National Knowledge Infrastructure were searched for observational studies until September 2016. Then, we carried out a systematic review and dose-response meta-analysis using Stata 14.0 software. Subgroup analyses were further carried out according to study characteristics and adjustment confounders...
March 21, 2018: European Journal of Cancer Prevention
Frances Dovell, Paolo Boffetta
Elevated serum uric acid (SUA) is a marker of chronic inflammation and has been suggested to be associated with increased risk of cancer, but its antioxidant capacity would justify an anticancer effect. Previous meta-analyses did not include all available results. We conducted a systematic review of prospective studies on SUA level and risk of all cancers and specific cancers, a conducted a meta-analysis based on random-effects models for high versus low SUA level as well as for an increase in 1 mg/dl SUA...
March 21, 2018: European Journal of Cancer Prevention
Diama B Vale, Ahti Anttila, Antonio Ponti, Carlo Senore, Rengaswamy Sankaranaryanan, Guglielmo Ronco, Nereo Segnan, Mariano Tomatis, Maja P Žakelj, Klara M Elfström, Stefan Lönnberg, Joakim Dillner, Partha Basu
The aim of this study was to describe the compliance of the population-based cancer screening programmes in the European Union Member States to the invitation strategies enumerated in the European Guidelines and the impact of such strategies on the invitational coverage. Experts in screening programme monitoring from the respective countries provided data. Coverage by invitation was calculated as the proportion of individuals in the target age range receiving a screening invitation over the total number of annualized eligible population...
March 21, 2018: European Journal of Cancer Prevention
Chun-Xiao Lu, Xiao-Li Wu, Guang-Yuan Zhang, Xiao-Ting Gu, Xin Ma, Dong-Xu He
Cancer is one of the most important health problems today; therefore, many researchers are focusing on exploring the mechanisms underlying its development and treatment. The field of cancer epigenetics has flourished in recent decades, and studies have shown that different epigenetic events, such as DNA methylation, histone modification, and noncoding RNA regulation, work together to influence cancer development and progression. In this short review, we summarize the interactions between methylation and noncoding RNAs that affect cancer development...
March 19, 2018: European Journal of Cancer Prevention
Stephanie E Bonn, Matt J Barnett, Mark Thornquist, Gary Goodman, Marian L Neuhouser
The aim of this study was to investigate the association between BMI (kg/m) and prostate cancer risk. BMI is a modifiable lifestyle factor and may provide a unique opportunity for primary prevention of prostate cancer if a causal association exists. Data from 11 886 men from the Carotene and Retinol Efficacy Trial (CARET, 1985-1996 with active follow-up through 2005) comprising current and former heavy smokers were analyzed. CARET was a multicenter randomized, double-blind placebo-controlled chemoprevention trial testing daily supplementation of 30 mg β-carotene+25 000 IU retinyl palmitate for primary prevention of lung cancer...
March 7, 2018: European Journal of Cancer Prevention
Jian Dong, Minman Wu, Jiarong Miao, Tao Zhi, Tianmei Zhang, Gang Yang, Yarong Chen, Lei Zhang, Qiong Nan
The role of surveillance colonoscopy has long been established: it reduces both the incidence and the mortality of colorectal cancer. We aimed to assess the optimal colonoscopy surveillance interval period for the adenoma patients who underwent an adequate polypectomy at baseline colonoscopy to avoid overuse or underuse of colonoscopy. A retrospective study was carried out on the baseline adenoma patients who had had at least two completed colonoscopy examinations during the years 2000-2013 in the Digestive Endoscopy Center of the First Affiliated Hospital of Kunming Medical University...
February 23, 2018: European Journal of Cancer Prevention
Juliana F Roos, Mariam Qudsi, Arwa Samara, Madina M Rahim, Samar A Al-Bayedh, Hafez Ahmed
Diabetes mellitus has been associated with increased risk for the development of many types of cancer. Metformin, an oral medication and first-line treatment for type 2 diabetes mellitus, has been suggested to reduce cancer risk and mortality in various types of cancer. This study focuses on assessing metformin association with lung cancer as reported in the literature. Recent studies and reviews investigating metformin effects on lung cancer incidence and patient survival are critically and systematically discussed...
February 23, 2018: European Journal of Cancer Prevention
Giovanni Corso, Paolo Veronesi, Virgilio Sacchini, Viviana Galimberti
No abstract text is available yet for this article.
May 2018: European Journal of Cancer Prevention
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