Najma Qammar, Maryam Zain, Raheela Jabeen, Farah Deeba, Nadia Iqbal, Hafiz Muhammad Rashad Javeed, Fatema Suliman Alatawi, Mohsen Suliman Alatawi, Sanaa Almowallad, Amnah A Alharbi, Hüseyin Şahin
The genetics of organisms play a vital role in the development of coronary artery disease (CAD), with its heritability estimated at approximately 50-60%. For this purpose, we examined the relationship between CAD risk and C12orf43/rs2258287 polymorphisms in the Pakistani population. In this study based on the genetic approach to dyslipidemia, a total of 200 subjects were included from the southern Punjab. The biochemical analysis of parameters (total cholesterol, triglycerides, blood glucose, high-density lipoprotein, and low-density lipoprotein) was carried out along with molecular analysis using an ARMS-PCR-based assay for single-nucleotide polymorphism (SNP) C12orf43/rs2258287 to identify the genotype...
February 29, 2024: Cellular and Molecular Biology