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Journal of the European Academy of Dermatology and Venereology: JEADV

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https://www.readbyqxmd.com/read/28627111/european-surveillance-system-on-contact-allergies-essca-results-with-the-european-baseline-series-2013-14
#1
W Uter, J C Amario-Hita, A Balato, B Ballmer-Weber, A Bauer, A Belloni Fortina, A Bircher, M M U Chowdhury, S M Cooper, A Dugonik, R Gallo, A Giménez-Arnau, J D Johansen, S M John, M Kieć-Świerczyńska, T Kmecl, B Kręcisz, F Larese Filon, V Mahler, M Pesonen, T Rustemeyer, A Sadowska-Przytocka, J Sánchez-Perez, S Schliemann, M L Schuttelaar, D Simon, R Spiewak, S Valiukeviciene, E Weisshaar, I R White, S M Wilkinson
BACKGROUND: Contact allergy is a common condition and can severely interfere with daily life or professional activities. Due to changes in exposures, a consequence of introduction of new substances, new products or formulations, and regulatory intervention, the spectrum of contact sensitisation changes. OBJECTIVE: To evaluate the current spectrum of contact allergy to allergens present in the European baseline series (EBS) across Europe. METHODS: Retrospective analysis of data collected by the European Surveillance System on Contact Allergies (ESSCA, www...
June 19, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28627095/sporotrichosis-masquerading-as-pyoderma-gangrenosum
#2
R B Lima, M A J Jeunon-Sousa, T Jeunon, J C Oliveira, M M E Oliveira, R M Zancopé-Oliveira, A C S Moraes
Sporotrichosis is a subcutaneous mycosis with a worldwide distribution caused by species of the Sporothrix schenkii complex. Since 1998, it has reached epidemic proportions in the city of Rio de Janeiro, Brazil, via transmission from infected cats to humans. The species identified as the primary cause was Sporothrix brasiliensis. This article is protected by copyright. All rights reserved.
June 19, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28626861/diphenylcyclopropenone-for-the-treatment-of-cutaneous-in-transit-melanoma-metastases-results-of-a-prospective-non-randomised-single-centre-study
#3
T Read, S Webber, J Tan, M Wagels, H Schaider, H P Soyer, B M Smithers
BACKGROUND: Current treatments for in-transit melanoma (ITM) metastases are frequently invasive and do not improve overall survival. Recently there has been increasing investigation into the use of topical agents for ITM. Diphenylcyclopropenone or diphencyprone (DPCP) is a novel, topical agent that has been reported to have immune-sensitising properties useful in the treatment of ITM. OBJECTIVE: To assess the clinical outcomes of patients treated within a prospective, non-randomised, non-comparative study using DPCP for cutaneous in-transit melanoma metastases...
June 19, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28622458/bullous-pemphigoid-associated-with-silicosis
#4
T Zhu, D L Ma, Y P Zeng, L Song, L Li
An 87-year-old man presented with multiple erythemas accompanied by itching on bilateral axillae, groins and buttocks for 3 months, which aggravated with blisters and bullae for 1 month. The physical examination revealed multiple tense blisters and bullae with erosions and light yellow effusion (Fig. 1a). The histopathological examination of the tissue biopsy showed a subepidermal blister with little inflammatory infiltrate (Fig. 1b). This article is protected by copyright. All rights reserved.
June 16, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28622444/paraneoplastic-pemphigus-in-two-pairs-of-brothers
#5
B Kranzelbinder, T Hashimoto, M Joch, W Salmhofer, H Reiter, J Bauer, E Aberer
A 65-year-old man (Patient 1A) presented with erosions on the face, upper trunk and the oral mucosa in 1995 (Table 1). He underwent prostatectomy for prostate cancer in 1990. PNP was proven by antibodies to IgG anti-epithelial cell surface (ECS), desmoglein (Dsg)1, and Dsg3. This article is protected by copyright. All rights reserved.
June 16, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28622428/cutaneous-pseudomyogenic-epithelioid-sarcoma-like-hemangioendothelioma-fosb-immunohistochemistry-demonstrating-the-serpine1-fosb-fusion-gene
#6
Victoria Alegría-Landa, Carlos Santonja, Margarita Jo-Velasco, Heinz Kutzner, Luis Requena
Pseudomyogenic hemangioendothelioma is a distinctive vascular neoplasm characterized by a multicentric presentation that mostly involves the lower extremities of young adults. Histopathologic resemblance to epithelioid sarcoma and co-expression of both keratins and endothelial markers are its hallmarks. A specific SERPINE1-FOSB fusion gene derived from t(7;19)(q22;q13) with significantly higher FOSB mRNA expression in neoplastic cells is the characteristic cytogenetic anomaly of this tumor. This article is protected by copyright...
June 16, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28622425/adalimumab-use-in-patients-with-psoriasis-and-hepatitis-b-a-case-series
#7
D J No, M Amin, J J Wu
Tumor necrosis factor (TNF) inhibitors neutralize the biologic activity of TNF-alpha, a key cytokine involved in both the pathogenesis of psoriasis and host immune response in suppressing microbial proliferation.(1) It is well known that chronic hepatitis B virus (HBV) carriers are at high risk of HBV reactivation when using immunosuppressive medications, chemotherapy, and TNF inhibitors.(2-4) However, HBV reactivation in patients with resolved HBV infection using TNF inhibitors is exceedingly rare, and to our knowledge has not been reported in the psoriasis literature...
June 16, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28622423/-congenital-dermatofibrosarcoma-protuberans-clinically-mimicking-a-melanocytic-nevus-treated-with-serial-excisions
#8
J Laske, M Sergon, T Mentzel, S Beissert, J Maschke
A 9-year-old female patient was referred to our department with the clinical diagnosis of a congenital melanocytic nevus on the back for serial excisions. The child's parents confirmed that the lesion existed since birth. Only little changes in color and size were observed over the years. The lesion was painless. This article is protected by copyright. All rights reserved.
June 16, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28622416/rosacea-and-demodicidosis-associated-with-gain-of-function-mutation-in-stat1
#9
Julie Second, Anne-Sophie Korganow, Sarah Jannier, Anne Puel, Dan Lipsker
We report a family in which 3 of 5 children as well as the mother, had a gain-of-function (GOF) mutation in the signal transducer and activator of transcription (STAT1) associated with early-onset rosacea and demodicidosis. The proband case (Fig. 1) was a 13-year-old boy of non-consanguineous parents, known for a hypothyroidism, failure to thrive and chronic mucocutaneous candidiasis (CMC) since he was 5-6 years old. On examination, he had medio-facial erythema with telangiectasia, as well as sometimes pruritic papulopustular lesions of the face and neck...
June 16, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28622414/reflectance-confocal-microscopic-presentation-of-basosquamous-carcinoma
#10
A Oliveira, I Zalaudek
Basosquamous carcinoma (BSC) is considered a variant of basal cell carcinoma (BCC) associated with squamous differentiation.(1) It may display local aggressive behavior, and increased potential for recurrence and metastases.(2) Therefore, early and appropriate treatment will have prognostic repercussion. This article is protected by copyright. All rights reserved.
June 16, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28622413/observations-from-our-evaluation-of-body-weight-changes-after-initiation-of-a-biologic-therapy-in-psolar
#11
N H Shear, R Alhusayen, A Fernandez-Obregon, A B Kimball, A Menter, J J Wu, K Goyal, H Patel, R Lin, A W Armstrong
PSOLAR is a global, prospective, observational study designed to evaluate long-term safety and clinical outcomes for over 12,000 psoriasis patients who are receiving, or are eligible to receive, biologic and/or conventional systemic agents. Data from the registry may also be used to test hypotheses for topics of interest to dermatologists.(1) While PSOLAR has produced many viable analyses of safety and efficacy outcomes, including overall safety, serious infections, comparative effectiveness, and persistence of treatment,(2-5) a recently tested hypothesis related to treatment effect on body weight did not generate interpretable results...
June 16, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28621909/systemic-therapy-of-ocular-and-cutaneous-rosacea-in-children
#12
L I Gonser, C E Gonser, C Deuter, M Heister, M Zierhut, M Schaller
BACKGROUND: In paediatric rosacea, ocular symptoms are often predominant. Literature about systemic therapy of paediatric ocular rosacea is sparse, though. OBJECTIVE: Analysis of children with ocular rosacea treated systemically, particularly addressing remission and recurrence rates. METHODS: Retrospective study reviewing the medical records of children with ocular rosacea treated with systemic antibiotic therapy. Nine out of 19 patients were chosen for detailed analysis...
June 16, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28609605/diagnostic-accuracy-of-skin-lesions-amongst-plastic-surgeons-and-a-dermatologist
#13
Christopher A Stone, Anthony M R Downs
There have been few studies investigating diagnostic accuracy between plastic surgeons, or comparing this with dermatologists. Use of dermoscopy by dermatologists has widened the diagnostic gap between dermatologists and plastic surgeons, with plastic surgery lagging behind dermatology in learning this technique. Consequently, plastic surgeons are likely to have a lower threshold for performing a diagnostic or excisional biopsy than dermatologists, leading to a higher rate of intervention for lesions that could otherwise be managed non-surgically...
June 13, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28609589/hyperbilirubinemia-the-common-denominator-of-yellow-urticaria
#14
A Combalia, X Fustà, A Guilabert, J M Mascaró, T Estrach
Rosso et al recently enlarged to ten the list of patients diagnosed with yellow urticaria (YU). These cases of YU remind clinicians that the skin, besides forming a biological barrier to protect internal organs and systems from the external environment, frequently reflects underlying internal diseases. YU has been described secondary to infective hepatitis1, liver cirrhosis (regardless of the cause) (2, 3, 4, 5, 6) , acute liver failure(7) , and metastatic disease of the liver(8) . This article is protected by copyright...
June 13, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28609574/factors-associated-with-the-choice-of-the-first-biologic-in-psoriasis-real-life-analysis-from-the-psobioteq-cohort
#15
Emilie Sbidian, Caroline Giboin, Hervé Bachelez, Carle Paul, Marie Beylot-Barry, Alain Dupuy, Manuelle Viguier, Jean-Philippe Lacour, Jean-Luc Schmutz, Pierre Bravard, Emmanuel Mahé, Nathalie Beneton, Laurent Misery, Emmanuel Delaporte, Philippe Modiano, Sébastien Barbarot, Elodie Regnier, Denis Jullien, Marie-Aleth Richard, Pascal Joly, Florence Tubach, Olivier Chosidow
BACKGROUND: Decision making is a complex process. The aim of our study was to assess factors associated with the choice of the first biological treatment in patients with moderate-to-severe psoriasis. METHODS: Data on all patients included in the French prospective, observational, cohort, Psobioteq and initiating a first biologic prescription between July 2012 and July 2016 were analysed. Demographic information and clinical features were collected during routine clinical assessments by the dermatology team at the recruiting centres using a standardized case report form...
June 13, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28609573/psoriasis-comorbidity-affects-multiple-sclerosis-neurological-progression-a-retrospective-case-control-analysis
#16
G Miron, M Gurevich, S Baum, A Achiron, A Barzilai
BACKGROUND: Multiple sclerosis (MS) and psoriasis are inflammatory disorders, with epidemiological and biological associations. The impact of one disease on the course of the other has not been studied. OBJECTIVE: To characterize patients with psoriasis and MS, and to assess whether psoriasis comorbidity affected the progression of MS. METHODS: A retrospective case control study. Patients with psoriasis comorbidity were identified from 3456 patients included in the Sheba Hospital Multiple Sclerosis Center database...
June 13, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28609562/cryptogenic-cirrhosis-misunderstood-cause-of-yellow-urticaria
#17
Mariana Boechat Souza, Teresa Russo, Lilian Mathias Delorenze, Gabriela Castro, Giuseppe Argenziano, Vincenzo Piccolo
We read with great interest the paper by Combalia et al recently appeared on Journal of European Academy of Dermatology(1) . The authors reported two cases of yellow urticaria related to liver cirrhosis, one due to hemochromatosis, and the other one to alcohol(1) . With a total of ten cases reported in literature by now, we considered relevant to report another case we recently came across. This article is protected by copyright. All rights reserved.
June 13, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28609556/prevention-of-livedoid-vasculopathy-recurrence-by-prolonged-administration-of-rivaroxaban
#18
Ch Drerup, T Goerge
A 49-year-old man with known livedoid vasculopathy presented with recurrent painful (VAS 8/10) ulceration and necrosis on the foot (Figure 1). He was formerly treated with prostacyclin infusions, acetylsalicylic acid, intravenous immunoglobulins, different systemic antibiotics and a skin grafting. At admission an antithrombotic therapy with enoxaparin (Clexane(®) ) in a dose of 1 mg/ kg bodyweight (100 mg) once daily was initiated. This article is protected by copyright. All rights reserved.
June 13, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28609554/digit-preserving-surgery-of-subungual-melanoma-a-case-series-using-vacuum-assisted-closure-and-full-thickness-skin-grafting
#19
D Crisan, J Gülke, C Janetzko, S Kastler, N Treiber, K Scharffetter-Kochanek, L A Schneider
Acrolentiginous melanoma (ALM) is the second most common nail organ tumour and frequently, affects the thumb or the great toe.(1,2) Digit amputation is still the gold standard for many surgeons;(3) it does, however, not protect against local recurrence. An alternative represents complete tumour resection with distal phalanx preservation, which has proven valuable, especially for well demarcated thinner tumours.(4,5) This article is protected by copyright. All rights reserved.
June 13, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28609551/chronic-exposure-to-tetracyclines-and-subsequent-diagnosis-for-non-melanoma-skin-cancer-in-a-large-midwestern-u-s-patient-population
#20
P P Vakharia, B Nardone, B J Schlosser, D Lee, L Serrano, D P West
Tetracyclines (TCNs) are commonly used in the management of several chronic dermatological disorders, partly due to their affinity for inflamed skin tissue, as they are known to suppress cytokines including tumor necrosis factor-alpha and interleukin-6 that are typically involved in inflammatory skin disorders.(1) TCNs are known to be photoreactive following ultraviolet (UV) radiation exposure, a known risk factor for the development of nonmelanoma skin cancer (NMSC), notably basal cell carcinoma (BCC) and squamous cell carcinoma (SCC)...
June 13, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
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