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Journal of the European Academy of Dermatology and Venereology: JEADV

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https://www.readbyqxmd.com/read/27911476/nd-yag-and-pulsed-dye-laser-therapy-in-infantile-hemangiomas-a-retrospective-analysis-of-271-treated-hemangiomas-in-149-children
#1
F Hartmann, A Lockmann, L-L Grönemeyer, H A Haenssle, M Zutt, H von Fintel, I Kühnle, M P Schön, K-M Thoms
BACKGROUND: Infantile hemangiomas (IH) are common benign tumors in infancy. Most IH resolve spontaneously, but some require treatment due to ulceration, functional impairment or cosmetic disfiguration. While systemic propranolol is effective in many cases, laser therapy may be a safe topical alternative. OBJECTIVE: To assess the efficacy of combined Nd:YAG/pulsed dye laser (PDL) or PDL alone for therapy of IH. PATIENTS AND METHODS: 271 IH in 149 infants were treated with combined Nd:YAG/PDL or PDL alone...
December 2, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27911016/positive-impact-of-omalizumab-on-angioedema-and-quality-of-life-in-patients-with-refractory-chronic-idiopathic-spontaneous-urticaria-analyses-according-to-the-presence-or-absence-of-angioedema
#2
M Maurer, H Sofen, B Ortiz, F Kianifard, S Gabriel, J A Bernstein
BACKGROUND: Approximately 50% of patients with chronic idiopathic/spontaneous urticaria (CIU/CSU) report hives and angioedema; some experience hives/ angioedema only. OBJECTIVE: Assess omalizumab's effect on angioedema and quality of life (QoL) in subgroups with refractory CIU/CSU: those with and without angioedema. METHODS: Patients received omalizumab (75, 150 or 300 mg) or placebo every 4 weeks for 12/24 weeks. Angioedema and QoL was assessed (Urticaria Patient Daily Diary and Dermatology Quality of Life Index [DLQI])...
December 2, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27911007/assessment-of-subclinical-atherosclerosis-in-hidradenitis-suppurativa
#3
José C Pascual, Iris González, Diego Corona, Patricia Hispán, José M Ramos, José Sánchez-Paya, Gregor B Jemec
BACKGROUND: Patients with Hidradenitis Suppurativa (HS) have an increased prevalence of traditional cardiovascular (CV) risk factors. OBJECTIVE: Our aim was to investigate the association between subclinical atherosclerosis, detected by carotid ultrasound, and HS. METHODS: A prospective observation and analytical study assessing subclinical atherosclerosis using carotid ultrasound in patients with HS. RESULTS: A total of 62 HS-patients and 62 matched-controls were studied...
December 2, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27896884/contact-allergy-to-preservatives-essca-results-with-the-baseline-series-2009-2012
#4
Ana M Giménez-Arnau, Gustavo Deza, Andrea Bauer, Graham A Johnston, Vera Mahler, Marie-Louise Schuttelaar, Javier Sanchez-Perez, Juan Francisco Silvestre, Mark Wilkinson, Wolfgang Uter
BACKGROUND: Allergic contact dermatitis caused by biocides is common, and causes significant patient morbidity. OBJECTIVE: To describe the current frequency and pattern of patch test reactivity to biocide allergens included in the baselines series of most European countries. METHODS: Data collected by the European Surveillance System on Contact Allergies (ESSCA) network between 2009 and 2012 from 12 European countries were analysed. RESULTS: Methylisothiazolinone 0...
November 29, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27896881/nympho-hymenal-tear-a-distinctive-entity
#5
Giang Huong Nguyen, Nicklaus Lang, Stephan Lautenschlager
Vulvar fissures are linear tears extending into the dermis. When in the posterior fourchette, it is known as granuloma fissuratum plicae labioalveolaris, or vulvar granuloma fissuratum, a term first described by Sutton et al. in 1932. (1) The other pattern are small fissures occurring at other vulvar locations, and sexually active patients report entry dyspareunia. (2-8) In majority of cases, vulvar fissures are secondary findings in a plethora of inflammatory dermatoses or infections, rarely, can occur as primary findings without any apparent causes...
November 29, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27896876/sites-of-recurrence-in-patients-following-clearance-of-psoriasis-with-biologic-therapy
#6
D J No, M Amin, S P Reddy, A Egeberg, J J Wu
Management of psoriasis has vastly improved since the emergence of biologic medications, however such drugs tend to lose effectiveness with extended use.(1) We assessed the distribution of psoriatic lesions that reoccur in patients who experienced a loss of efficacy from their biologic medication. This retrospective chart review focused on patients with psoriasis who presented to Kaiser Permanente Los Angeles Medical Center from January 2008 to September 2016. This article is protected by copyright. All rights reserved...
November 29, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27896875/disseminated-cobblestone-like-skin-lumps-in-a-newborn
#7
Z X Ren, H Q Jiang, L X Zhang, Q D Deng, J Y Zhang, X P Mu, J Yang
An newborn boy showed multiple skin lumps at birth. On examination, there were disseminated red cobblestone-like skin neoplasms, 5-30mm in diameter with hard serosanguineous crust, some were with scabs, over the scalp, face, trunk and extremities (Fig. 1A,B). The liver was 3 cm palpable below the costal margin. He was active and stable. The mother' prenatal investigation on antibodies of rubella, herpes simplex virus (HSV) and hepatitis B surface antigen were positive. The baby's antibodies for HAV, HBV, HCV, rubella, HSV, HIV and syphilis were negative...
November 29, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27896872/sunbed-use-among-portuguese-beach-goers-a-crave-group-while-wainting-sunbeds-to-be-abolished
#8
A F Duarte, J N Maia Silva, A Costa Pereira, E Nagore, A Picoto, O Correia
Although sunbed use is considered a complete carcinogen for skin cancer, over the past decades exposure to indoor tanning is becoming more popular.(1, 2) The risk appears to be stronger for young women, initial use at an early age (less than 35 years) and higher number of sunbed sessions. (3, 4) With this study we aim to better understand the features of sunbed users in Portuguese beach goers, a group at high risk for skin cancer. This article is protected by copyright. All rights reserved.
November 29, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27896871/the-old-reliables-outperform-new-media-in-social-marketing-of-euromelanoma-in-ireland
#9
L Roche, C C Foley, S McCarthy, M Murphy
Euromelanoma is a pan-European prevention campaign against skin cancer and promotes a walk-in screening day in May of each year. The screening day serves to highlight awareness of skin cancer amongst the general public and to encourage self-checks for new or changing lesions. The South Infirmary Victoria University Hospital (SIVUH) provides regional dermatology and skin cancer services for the Cork/Kerry region in Ireland and held a Euromelanoma Screening day in May 2014 and 2015. This article is protected by copyright...
November 29, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27896870/tetracyclines-and-or-nicotinamide-in-blistering-dermatoses
#10
Ayman Abdelmaksoud
I read with interest a report by von Köckritz et al(1) . Tetracycline therapy, particularly in autoimmune blistering conditions, has become an acceptable treatment modality among elderly individuals, particularly those with osteoporosis, DM, and hypertension. This drug has also been given in combination with immunosuppressive treatment for more rapid tapering of the latter(2) .Minocycline besides having antimicrobial activity, it possesses anti-inflammatory and anti-apoptotic properties and causes inhibition of proteolysis, angiogenesis, and collagenase, and ability to induce read-through of premature stop mutations(3) ...
November 29, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27896861/cyclosporine-a-for-severe-atopic-dermatitis-in-children-efficacy-and-safety-in-a-retrospective-study-of-63-patients
#11
A Hernández-Martín, L Noguera-Morel, B Bernardino-Cuesta, A Torrelo, M A Pérez-Martin, C Aparicio-López, C de Lucas-Collantes
BACKGROUND: Cyclosporin A (CSA) is an immunosuppressant agent widely used in severe atopic dermatitis (AD). However, experience in children is limited. OBJECTIVES: To assess the efficacy and adverse events of CSA therapy in children. METHODS: Retrospective study of children with severe AD treated with CSA between January 2009 and December 2015. RESULTS: Data from 63 patients were collected. Mean age at the beginning of treatment was 8...
November 29, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27896853/melanomas-versus-nevi-in-high-risk-patients-under-long-term-monitoring-with-digital-dermatoscopy-do-melanomas-and-nevi-already-differ-at-baseline
#12
P Tschandl, L Hofmann, C Fink, H Kittler, H A Haenssle
BACKGROUND: What lesions to select for a most efficient dermatoscopic monitoring of patients with multiple nevi remains an unresolved issue. OBJECTIVE: To compare the grade of atypia of melanomas and nevi of the same patient at baseline. METHODS: Prospective observational study using 236 dermatoscopic baseline images (59 quartets from 59 patients, each including 1 melanoma detected during follow-up and 3 nevi). Dermatologists (n=26) were asked to assess the "grade of dermatoscopic atypia" on a numerical scale and to identify the melanomas...
November 29, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27879012/crusted-impetigo-like-lesion-on-the-face-a-case-of-igg-iga-pemphigus
#13
R Moriuchi, T Ito, K Kikuchi, N Nakashita, R Muramatsu, K Natsuga, H Shimizu, S Shimizu
In recent years, cases of IgG/IgA pemphigus, a rare subtype of pemphigus characterized by circulating IgG and IgA autoantibodies against the keratinocyte cell surface have been reported.(1-6) The cutaneous manifestations of IgG/IgA pemphigus were reported to resemble those of IgA pemphigus in form, including the presence of pustules and annular lesions.(1) However, no consensus on what eruptions are typical of IgG/IgA pemphigus has been established, due to the rarity of this disease. In this report, we describe a case of IgG/IgA pemphigus who developed severe crusted lesions on the seborrheic area that closely resembled facial crusted impetigo...
November 23, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27879009/epidemiological-dermoscopical-and-pathological-evaluation-of-melanocytic-lesions-of-the-buttock-in-a-5-year-period-a-female-prevalence
#14
Giovanni Paolino, Iris Zalaudek, Anna Carbone, Pasquale Frascione, Michele Donati, Chiara Panetta, Pietro Donati
A self-assessment of the skin plays a pivotal role in the early diagnosis of melanoma. However, when pigmented lesions are located on hidden areas or on locations that are difficult to self-examine, their assessment becomes more difficult. This article is protected by copyright. All rights reserved.
November 23, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27879008/quality-of-life-measurement-in-atopic-dermatitis-position-paper-of-the-european-academy-of-dermatology-and-venereology-eadv-task-force-on-quality-of-life
#15
REVIEW
P V Chernyshov, L Tomas-Aragones, L Manolache, S E Marron, Salek, F Poot, A P Oranje, A Y Finlay
There is a need for researchers to have easy reference to the wide spectrum of different types of quality of life (QoL) instruments that can be used in atopic dermatitis (AD). Previous reviews on QoL in AD do not cover the full spectrum of QoL measures used in studies on AD. This paper, on behalf of the European Academy of Dermatology and Venereology (EADV) Task Force on QoL contains information on instruments available for health-related QoL and family QoL assessment in AD including information on validation, experience of QoL assessment in AD for different purposes, peculiarities of QoL assessment in different age groups, expert analysis of available instruments including data on limitations of their use and recommendations of the Task Force...
November 23, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27878887/why-do-young-adults-tan
#16
Charlotte L Thomas, Pablo Fernández Peñas
Australia has the highest incidence of non-melanoma skin cancer (NMSC)(1) . NMSC evolution is strongly linked to ultraviolet (UV) radiation exposure (2) and is largely preventable through its reduction. Prominent Australian public health campaigns since the 1980s (3) aimed to educate the public about the dangers of excessive sun exposure and the need for sun-protection, assuming that increased knowledge will be translated into behavioural change. However, positive attitudes towards tanned skin have been shown to correlate with UV exposure(4,5) ...
November 23, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27878885/beware-when-the-hair-turns-dark-again-clinical-presentation-and-management-of-melanoma-in-situ-in-a-giant-congenital-naevus-on-the-scalp
#17
Diana Crisan, Karin Scharffetter-Kochanek, Reinhard Dummer, Nicolai Treiber, Anca Sindrilaru, Sabine Kastler, Lars Alexander Schneider
A 74-year-old man presented with a congenital naevus of the scalp that has lost its pigmentation over lifetime. Lately, he noticed a newly darkening patch within the grey hair area covering the naevus. The clinical examination revealed a palm-sized area of heavily pigmented hair on a 15x20 cm irregularly pigmented, poorly demarcated brown patch. This article is protected by copyright. All rights reserved.
November 23, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27878882/tamoxifen-may-cause-life-threatening-angioedema-attacks-in-patients-with-hereditary-angioedema
#18
K Bork, K Wulff, G Witzke, S Rietz, J Hardt
Tamoxifen had been described as a triggering factor for hereditary angioedema (HAE) due to C1 inhibitor (C1-INH) deficiency (HAE-C1-INH).(1, 2) We report on a patient with HAE and normal C1-INH and a further patient with HAE-C1-INH with a life-threatening exacerbation due to tamoxifen. Patient 1: A now 73 year-old woman had a family history negative for angioedema. She reported 3 lip swellings during the second and third trimester of her second pregnancy at age 23. This article is protected by copyright. All rights reserved...
November 23, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27878874/lymphocytes-from-patients-with-cutaneous-t-cell-lymphoma-show-dna-instability-and-reduced-dna-repair-using-the-comet-assay
#19
Kristian Thestrup-Pedersen, Chen Wang
We have shown that cutaneous T cell lymphoma (CTCL) is associated with the presence of genotraumatic T lymphocytes1,2. In order to study the genetic stability in lymphocytes from CTCL, we used the Comet assay3. This assay measures DNA damage and can measure DNA repair after DNA damage following low-dosage X-rays or UV light. In a gel electrophoresis spreading of DNA pieces can be visualized3. In order to measure DNA repair, cells can be left for certain time periods before subjected to electrophoresis. Lymphocytes from healthy persons repair their DNA damage, but here we document that this is not the case with blood and skin-homing T lymphocytes from CTCL patients even in the early stages of disease...
November 23, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27859657/capecitabine-and-adermatoglyphia-trouble-in-border
#20
C Mazza, F Slimano, L Visseaux, M A Ordan, D Botsen, F Grange, O Bouche
Capecitabine, an oral prodrug of 5-fluorouracil, is approved in stage III colon cancer (1) and metastatic colorectal and breast cancer (2) (3). Palmo-plantar erythrodysesthesia, also known as Hand Foot syndrome (HFS), is its most limiting toxicity. Although it is not life threatening, it can compromise efficacy because of dose reduction. It has been reported in pivotal trials in 53% of patients receiving capecitabine, requiring dose reduction in 17% of patients (2). This article is protected by copyright. All rights reserved...
November 17, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
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