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Breast: Official Journal of the European Society of Mastology

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https://www.readbyqxmd.com/read/28327352/update-on-the-diagnosis-and-management-of-malignant-phyllodes-tumors-of-the-breast
#1
REVIEW
Matthew Strode, Thaer Khoury, Christopher Mangieri, Kazuaki Takabe
Malignant phyllodes tumors of the breast are a rare entity. They occur infrequently but most often in younger women in comparison to typical epithelial-based breast cancers. Treatment of these tumors is not without controversy and in this review we will present an update on the diagnosis and management of malignant phyllodes tumors of the breast.
March 16, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28288387/can-we-make-a-portrait-of-women-with-inoperable-locally-advanced-breast-cancer
#2
Giacomo Montagna, Andres R Schneeberger, Lorenzo Rossi, Gabriella Bianchi Micheli, Francesco Meani, Mauro Imperiali, Alessandra Spitale, Olivia Pagani
INTRODUCTION: Delay between clinical presentation and treatment of breast cancer (BC) can significantly impact mortality. We aimed at drawing a picture of women with locally advanced breast cancer (LABC) treated at our Breast Unit and at investigating factors associated with treatment delay. MATERIAL AND METHODS: A retrospective descriptive analysis, using a specific 28-item semi-structured questionnaire, was conducted in 67 patients diagnosed with T4 BC. RESULTS: Nearly a third of our patients had at least one known predisposing factor for LABC...
March 10, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28285890/cancer-related-cognitive-impairment-and-its-relation-to-ptsd
#3
LETTER
H Ian Robins, Laddie Johnson, Noelle LoConte, Kimberly Brandt
No abstract text is available yet for this article.
March 9, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28285236/efficacy-of-nepa-netupitant-palonosetron-across-multiple-cycles-of-chemotherapy-in-breast-cancer-patients-a-subanalysis-from-two-phase-iii-trials
#4
Hope S Rugo, Giorgia Rossi, Giada Rizzi, Matti Aapro
OBJECTIVES: Breast cancer (BC) patients represent a high-risk population for experiencing chemotherapy-induced nausea and vomiting (CINV), since they frequently receive highly emetogenic anthracycline-cyclophosphamide-based (AC) chemotherapy, and are often female and young, two predisposing risk factors for CINV. Guidelines recommend the combination of a neurokinin-1 receptor antagonist (NK1RA), 5-hydroxytryptamine-3 RA (5-HT3RA), and dexamethasone (DEX) for CINV prophylaxis in AC-treated patients...
March 9, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28284541/integration-of-psycho-oncology-through-the-whole-care-pathway-for-breast-cancer-patients-in-europe
#5
LETTER
L Neamţiu, S Deandrea, L Pylkkänen, C Freeman, J López-Alcalde, A Bramesfeld, Z Saz-Parkinson, A Ulutürk, D Lerda
No abstract text is available yet for this article.
March 8, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28284061/fertility-concerns-among-breast-cancer-patients-in-mexico
#6
Cynthia Villarreal-Garza, Bertha Alejandra Martinez-Cannon, Alejandra Platas, Alejandro Mohar, Ann H Partridge, Arnoldo Gil-Moran, Alan Fonseca, Yoatzin Vega, Enrique Bargallo-Rocha, Servando Cardona-Huerta, Yadira Estefany Lopez-Aguirre, Regina Barragan-Carrillo, Andrea Castro-Sanchez
OBJECTIVE: Young women represent a high proportion of the total number of breast cancer (BC) patients in Mexico; however, no previous studies addressing their attitudes regarding the risk of chemotherapy-induced infertility and its contributing factors are available. The aim of this study was to evaluate the concerns of young women with BC towards the risk of infertility in two referral centers in Mexico with access to public health services. METHODS: A cross-sectional study including women with newly or previously detected BC aged 40 years or younger at diagnosis was conducted...
March 8, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28282588/axillary-reverse-mapping-in-n0-patients-requiring-sentinel-lymph-node-biopsy-a-systematic-review-of-the-literature-and-necessity-of-a-randomised-study
#7
REVIEW
R M Parks, K L Cheung
OBJECTIVES: Axillary reverse mapping (ARM) is a technique to map and preserve arm lymphatics which may be damaged during surgery, resulting in lymphoedema. This work systematically reviews the incidence of lymphoedema following sentinel lymph node biopsy (SLNB) + ARM, compared to SLNB alone, for clinically node negative disease, as well as recurrence rate, other morbidity and the feasibility and difficulties of ARM. MATERIALS AND METHODS: The following databases were searched: PubMed, Embase, Cochrane Library...
March 7, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28282587/feasibility-of-magnetic-marker-localisation-for-non-palpable-breast-cancer
#8
B Schermers, J A van der Hage, C E Loo, M T F D Vrancken Peeters, H A O Winter-Warnars, F van Duijnhoven, B Ten Haken, S H Muller, T J M Ruers
OBJECTIVES: Accurate tumour localisation is essential for breast-conserving surgery of non-palpable tumours. Current localisation technologies are associated with disadvantages such as logistical challenges and migration issues (wire guided localisation) or legislative complexities and high administrative burden (radioactive localisation). We present MAgnetic MArker LOCalisation (MaMaLoc), a novel technology that aims to overcome these disadvantages using a magnetic marker and a magnetic detection probe...
March 7, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28279888/validation-of-the-electronic-version-of-the-breast-q-in-the-army-of-women-study
#9
Sarah Fuzesi, Stefan J Cano, Anne F Klassen, Dunya Atisha, Andrea L Pusic
Women undergoing surgery for primary breast cancer can choose between breast conserving therapy and mastectomy (with or without breast reconstruction). Patients often turn to outcomes data to help guide the decision-making process. The BREAST-Q is a validated breast surgery-specific patient-reported outcome measure that evaluates satisfaction, quality of life, and patient experience. It was originally developed for paper-and-pencil administration. However, the BREAST-Q has increasingly been administered electronically...
March 6, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28279887/evaluation-of-percutaneous-vacuum-assisted-intact-specimen-breast-biopsy-device-for-ultrasound-visualized-breast-lesions-upstage-rates-and-long-term-follow-up-for-high-risk-lesions-and-dcis
#10
Cathy L Graham
OBJECTIVE: Percutaneous core biopsy of ultrasound visualized breast lesions is standard for diagnosis. Large gauge vacuum-assisted core needles have improved accuracy; but a significant underestimation of malignancy remains. The Intact(R) device was assessed for upstaging and subsequent malignancy at the biopsy site. METHODS: 469 consecutive ultrasound visualized breast lesions, < 2.0 cm in size, BIRADS 4 or 5, biopsied with Intact(R) Breast Lesion Excision System, between July 2007 and August 2014, were reviewed...
March 6, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28279886/secondary-gastric-cancer-malignancies-following-a-breast-cancer-diagnosis-a-population-based-analysis
#11
Alyson L Mahar, Daniel J Kagedan, Julie Hallet, Natalie G Coburn
OBJECTIVE: To quantify the population-risk of developing gastric cancer (GC) following breast cancer (BC). METHODS: GC incidence following a ductal or lobular BC were separately compared to incidence in the general United States population using SEER data. RESULTS: GC rates were similar to the general population for ductal BC. Women aged 35-75 with lobular BC had a significantly higher incidence of GC; women aged 40-44 had the highest risk...
March 6, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28273553/trial-sponsorship-and-self-reported-conflicts-of-interest-in-breast-cancer-radiation-therapy-an-analysis-of-prospective-clinical-trials
#12
Elton T T Leite, Fabio Y Moraes, Gustavo N Marta, Neil K Taunk, Marina T L Vieira, Samir A Hanna, João Luis F Silva, Heloisa A Carvalho
PURPOSE: We aim to assess any association between study and self-reported conflict of interest (COI) or trial sponsorship in breast cancer radiation clinical trials. MATERIALS AND METHODS: We searched PubMed for all clinical trials (CTs) published between 09/2004 and 09/2014 related to breast cancer. We included only radiotherapy CTs with primary clinical endpoints. We classified eligible trials according to the funding source, presence or absence of conflict of interest, study conclusion and impact factor (IF)...
March 5, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28273552/surgeon-performed-continuous-intraoperative-ultrasound-guidance-decreases-re-excisions-and-mastectomy-rates-in-breast-cancer
#13
Guldeniz Karadeniz Cakmak, Ali U Emre, Oge Tascilar, Burak Bahadir, Selcuk Ozkan
BACKGROUND: Intraoperative ultrasound guided (IUG) breast conserving surgery (BCS) is being increasingly embraced by breast surgeons worldwide. We aimed to compare the efficacy of IUG-BCS for palpable and nonpalpable breast cancer with respect to margin status, re-excision rate, tissue sacrifice and cost-time analysis. METHODS: Intraoperative localization protocol includes intraoperative ultrasound prior to excision to localize the lesion and guide the initial resection...
March 2, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28259045/development-and-validation-of-a-nomogram-for-predicting-survival-on-the-base-of-modified-lymph-node-ratio-in-breast-cancer-patients
#14
Jiahuai Wen, Yanning Yang, Peng Liu, Feng Ye, Hailin Tang, Xiaojia Huang, Shaowen Zhong, Xiaoming Xie
BACKGROUND: Axillary lymph node status is one of the most important prognostic factors in breast cancer and previous studies indicated that lymph node ratio (LNR) could better predict the outcome than the counting of positive lymph nodes. In the current study, we evaluated the prognostic effect of modified LNR in breast cancer patients. METHODS: A total of 3339 breast cancer patients undergoing axillary lymph nodes dissection were enrolled and respectively analyzed...
March 1, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28254641/role-of-total-tumour-load-of-sentinel-lymph-node-on-survival-in-early-breast-cancer-patients
#15
Vicente Peg, Irene Sansano, Begoña Vieites, Laia Bernet, Rafael Cano, Alicia Córdoba, Magdalena Sancho, María Dolores Martín, Felip Vilardell, Alicia Cazorla, Martín Espinosa-Bravo, José Manuel Pérez-García, Javier Cortés, Isabel T Rubio, Santiago Ramón Y Cajal
BACKGROUND: Axillary staging (pN) is considered one of the most important prognostic factors in breast cancer patients. However, the Z0011 study data drastically reduced the number of surgical axillary dissections in a selected group of patients, limiting the prognostic information relating to axillary involvement to the sentinel lymph node (SLN). It is known that there is a relationship between SLN total tumour load (TTL) and axillary involvement. The objective of this study is to analyse the relationship between the TTL and outcomes in patients with early stage breast cancer...
February 27, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28254640/age-and-treatment-related-associations-with-health-behavior-change-among-breast-cancer-survivors
#16
Chelsea Anderson, Dale P Sandler, Clarice R Weinberg, Kevin Houck, Minal Chunduri, M Elizabeth Hodgson, Susan A Sabatino, Mary C White, Juan L Rodriguez, Hazel B Nichols
OBJECTIVE: The aim of this study was to identify demographic and treatment-related factors associated with health-promoting behavior changes after a breast cancer diagnosis. Changes in health behaviors were also evaluated according to weight, exercise, diet and alcohol consumption patterns before breast cancer diagnosis. MATERIALS AND METHODS: We examined self-reported behavior changes among 1415 women diagnosed with breast cancer in the NIEHS Sister Study cohort...
February 27, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28238553/considerations-to-include-while-setting-policy-and-standards-for-psycho-oncological-care-in-breast-cancer-services-in-europe
#17
LETTER
Ozan Bahcivan, Kadri Altundag
No abstract text is available yet for this article.
February 24, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28209255/possible-external-factors-in-australia-when-referring-patients-who-consider-risk-reducing-mastectomies-rrm-and-contralateral-prophylactic-mastectomies-cpm-to-psychologists-in-oncology-care
#18
LETTER
Ozan Bahcivan, Kadri Altundag
No abstract text is available yet for this article.
February 10, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28189299/reply-to-dr-altundag-from-the-authors-of-omitting-radiation-therapy-in-women-with-triple-negative-breast-cancer-leads-to-worse-breast-cancer-specific-survival
#19
LETTER
Isabelle Kindts, Caroline Weltens
No abstract text is available yet for this article.
February 8, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28162837/immunotherapy-in-breast-cancer-an-introduction
#20
Mary L Disis, Sasha E Stanton
The field of breast cancer immunology has progressed tremendously over the last decade. Twenty years ago immunotherapy was not considered for the treatment of breast cancers because breast cancer was not considered immunogenic. Today we know that most patients with breast cancer have some evidence of an adaptive immune response against their tumors, detectable either in the peripheral blood or in the tumor. Moreover, immunity to breast cancer begins at the earliest stages of the disease, in some patients prior to diagnosis...
February 3, 2017: Breast: Official Journal of the European Society of Mastology
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