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Breast: Official Journal of the European Society of Mastology

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https://www.readbyqxmd.com/read/28068605/questionnaire-to-assess-quality-of-life-in-patients-with-breast-cancer-validation-of-the-chinese-version-of-the-eortc-qlq-br-53
#1
Zhen Zhang, Xian Zhang, Ling Wei, Yunshou Lin, Dongwen Wu, Shumin Xie, Lin Yue, Jingru Tian, Yu Zhang, Qijun Song, Stephenie Mu-Lian Woo, Adam R Miller, Le Luo, Lei Zhang
PURPOSE: To evaluate the reliability and validity of the Chinese version of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Breast Cancer (EORTC QLQ-BR53) questionnaire firstly in north of China. METHODS: A total of 294 outpatients with breast cancer in Tianjin Cancer Institution and Hospital from November 2014 to August 2015 were enrolled in this study. All patients self-administered the EORTC QLQ-BR25 and the Short Form 36 Health Survey (SF-36)...
January 6, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28064072/long-term-outcome-of-breast-cancer-patients-with-pathologic-n3a-lymph-node-stage
#2
Antonino Grassadonia, Patrizia Vici, Teresa Gamucci, Luca Moscetti, Laura Pizzuti, Lucia Mentuccia, Laura Iezzi, Maria Teresa Scognamiglio, Marinella Zilli, Jamara Giampietro, Vincenzo Graziano, Clara Natoli, Nicola Tinari
PURPOSE: To evaluate factors influencing the long-term outcome of patients presenting with 10 or more metastatic axillary lymph nodes (pN3a) after surgery for primary breast cancer. METHOD: Between January 1990 and December 2015, a total of 130 patients with pN3a breast cancer at surgery were identified in our Institutions and included in the study. Twenty-nine of them (22.3%) received neoadjuvant chemotherapy. The Multivariate Cox proportional hazards model was used to determine independent prognostic factors associated with DFS and OS...
January 5, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28063331/pcr-rates-in-patients-with-bilateral-breast-cancer-after-neoadjuvant-anthracycline-taxane-based-chemotherapy-a-retrospective-pooled-analysis-of-individual-patients-data-of-four-german-neoadjuvant-trials
#3
Mattea Reinisch, Jens Huober, Gunter von Minckwitz, Jens-Uwe Blohmer, Carsten Denkert, Claus Hanusch, Christian Jackisch, Sherko Kümmel, Andreas Schneeweiss, Kerstin Rhiem, Bianca Lederer, Michael Untch, Valentina Nekljudova V, Sibylle Loibl
PURPOSE: Patients with bilateral breast cancer (BBC) are usually excluded from participating in clinical trials and little is known about the response and outcome of BBC to neoadjuvant chemotherapy compared to unilateral BC (UBC). METHODS: We prospectively captured the information on patients with BBC in our database treated within four neoadjuvant chemotherapy trials and collected retrospectively the rate of pathological complete response (pCR) defined as ypT0 ypN0, ypT0/is ypN0, ypT0 ypNX, clinical and histologic parameters...
January 4, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28056400/efficacy-and-safety-of-eribulin-as-first-to-third-line-treatment-in-patients-with-advanced-or-metastatic-breast-cancer-previously-treated-with-anthracyclines-and-taxanes
#4
Shigeto Maeda, Michiyo Saimura, Shigeki Minami, Kaname Kurashita, Reiki Nishimura, Yuichiro Kai, Hiroshi Yano, Kohjiro Mashino, Shoshu Mitsuyama, Mototsugu Shimokawa, Kazuo Tamura
OBJECTIVES: Despite the survival benefit and acceptable tolerability of eribulin for advanced/metastatic breast cancer (MBC) patients pretreated with anthracyclines and taxanes, there is limited evidence of the clinical benefit of early eribulin use. We investigated the efficacy and safety of first- to third-line eribulin use in patients with MBC. MATERIALS AND METHODS: In this phase II, open-label, single-arm study conducted at 14 sites in Kyushu, Japan, women with histologically confirmed human epidermal growth factor receptor 2-negative MBC were enrolled between December 1, 2011 and November 30, 2013 (Data cut-off: November 30, 2014)...
January 2, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28038321/barriers-beliefs-and-practice-patterns-for-breast-cancer-reconstruction-a-provincial-survey
#5
Christopher J Coroneos, Karina Roth-Albin, Ajit S Rai, Amrit S Rai, Sophocles H Voineskos, Melissa C Brouwers, Ronen Avram, Barbara Heller
BACKGROUND: The purpose of this study was to characterize beliefs and practice patterns for breast cancer reconstruction among physicians who treat patients with breast cancer, in order to delineate current clinical practice. This survey was administered prior to Cancer Care Ontario guideline publication. METHOD: Survey questions addressed four domains: survival, delayed or obscured recurrence detection, delayed adjuvant therapy, and aesthetics. The survey was administered to 1160 Ontario plastic and general surgeons and radiation and medical oncologists...
December 27, 2016: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28033510/sentinel-node-detection-in-early-breast-cancer-with-intraoperative-portable-gamma-camera-uk-experience
#6
Debashis Ghosh, Nikolaos V Michalopoulos, Timothy Davidson, Fred Wickham, Norman R Williams, Mohammed R Keshtgar
PURPOSE: Access to nuclear medicine department for sentinel node imaging remains an issue in number of hospitals in the UK and many parts of the world. Sentinella(®) is a portable imaging camera used intra-operatively to produce real time visual localisation of sentinel lymph nodes. METHODS: Sentinella(®) was tested in a controlled laboratory environment at our centre and we report our experience on the first use of this technology from UK. Moreover, preoperative scintigrams of the axilla were obtained in 144 patients undergoing sentinel node biopsy using conventional gamma camera...
December 26, 2016: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28033509/atlas-based-segmentation-in-breast-cancer-radiotherapy-evaluation-of-specific-and-generic-purpose-atlases
#7
Delia Ciardo, Marianna Alessandra Gerardi, Sabrina Vigorito, Anna Morra, Veronica Dell'acqua, Federico Javier Diaz, Federica Cattani, Paolo Zaffino, Rosalinda Ricotti, Maria Francesca Spadea, Marco Riboldi, Roberto Orecchia, Guido Baroni, Maria Cristina Leonardi, Barbara Alicja Jereczek-Fossa
OBJECTIVES: Atlas-based automatic segmentation (ABAS) addresses the challenges of accuracy and reliability in manual segmentation. We aim to evaluate the contribution of specific-purpose in ABAS of breast cancer (BC) patients with respect to generic-purpose libraries. MATERIALS AND METHODS: One generic-purpose and 9 specific-purpose libraries, stratified according to type of surgery and size of thorax circumference, were obtained from the computed tomography of 200 BC patients...
December 26, 2016: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28033508/pathological-complete-response-in-invasive-breast-cancer-treated-by-skin-sparing-mastectomy-and-immediate-reconstruction-following-neoadjuvant-chemotherapy-and-radiation-therapy-comparison-between-immunohistochemical-subtypes
#8
J Barrou, M Bannier, M Cohen, E Lambaudie, A Gonçalves, P Bertrand, M Buttarelli, P Opinel, N Sterkers, A Tallet, C Zinzindohoué, G Houvenaeghel
CONTEXT: Even if neoadjuvant chemotherapy (NACT) and oncoplastic techniques have increased the breast conserving surgery rate, mastectomy is still a standard for multifocal or extensive breast cancers (BC). In the prospect of increasing breast reconstruction, an alternative therapeutic protocol was developed combining NACT with neoadjuvant radiation therapy (NART), followed by mastectomy with immediate breast reconstruction (IBR). The oncological safety of this therapeutic plan still needs further exploration...
December 26, 2016: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28030783/total-tumor-load-assessed-by-one-step-nucleic-acid-amplification-assay-as-an-intraoperative-predictor-for-non-sentinel-lymph-node-metastasis-in-breast-cancer
#9
Celso Nabais, Joana Figueiredo, Paulina Lopes, Manuela Martins, António Araújo
BACKGROUND: This study aimed to determine the relationship between CK19 mRNA copy number in sentinel lymph nodes (SLN) assessed by one-step nucleic acid amplification (OSNA) technique, and non-sentinel lymph nodes (NSLN) metastization in invasive breast cancer. A model using total tumor load (TTL) obtained by OSNA technique was also constructed to evaluate its predictability. METHODS: We conducted an observational retrospective study including 598 patients with clinically T1-T3 and node negative invasive breast cancer...
December 25, 2016: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28027811/letter-to-prof-yong-sheng-wang
#10
LETTER
Karla Ferreres García
No abstract text is available yet for this article.
December 24, 2016: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28024714/reply-to-sorscher-s
#11
LETTER
Frédéric Fiteni, Franck Bonnetain
No abstract text is available yet for this article.
December 23, 2016: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28017491/internal-mammary-sentinel-lymph-node-biopsy-an-effective-way-to-search-benefit-patients-and-guide-internal-mammary-chain-irradiation
#12
LETTER
Bin-Bin Cong, Xiao-Shan Cao, Peng-Fei Qiu, Jin-Ming Yu, Yong-Sheng Wang
No abstract text is available yet for this article.
December 22, 2016: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28017490/association-between-preoperative-serum-vitamin-d-and-high-density-lipoprotein-cholesterol-levels-and-effects-on-breast-cancer-prognosis
#13
LETTER
Kadri Altundag
No abstract text is available yet for this article.
December 22, 2016: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28013032/radiation-therapy-for-malignant-phyllodes-tumor-of-the-breast-an-analysis-of-seer-data
#14
Yi-Jun Kim, Kyubo Kim
PURPOSE: Malignant phyllodes tumor of the breast (MPTB) accounts for less than 1% of whole breast neoplasm. Surgery is regarded as the primary treatment of choice in patients with MPTB, but the necessity of postoperative radiation therapy (RT) has been a subject of debate. Our aim was to evaluate effects of postoperative RT for MPTB using a large population database. METHODS: Using the Surveillance, Epidemiology, and End Results Program (SEER) database (1983-2013), clinico-pathologic prognostic factors were evaluated...
December 22, 2016: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28012411/omitting-radiation-therapy-in-women-with-triple-negative-breast-cancer-leads-to-worse-breast-cancer-specific-survival
#15
I Kindts, P Buelens, A Laenen, E Van Limbergen, H Janssen, H Wildiers, C Weltens
PURPOSE: To examine locoregional recurrence (LRR) and breast cancer-specific survival (BCSS) after breast-conserving therapy (BCT) or mastectomy (ME) with or without radiation therapy (RT) in triple-negative breast cancer (TNBC). MATERIAL & METHODS: We identified non-metastatic TNBC cases from a single institution database. BCT, ME with RT (ME + RT) and ME only were compared with respect to LRR and BCSS. Cox regression models were used to analyze the association between prognostic factors and outcome...
December 21, 2016: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28012410/the-effect-of-marital-status-on-breast-cancer-related-outcomes-in-women-under-65-a-seer-database-analysis
#16
Leslie Hinyard, Lorinette Saphire Wirth, Jennifer M Clancy, Theresa Schwartz
BACKGROUND: Marital status is strongly associated with improved health and longevity. Being married has been shown to be positively associated with survival in patients with multiple different types of malignancy; however, little is known about the relationship between marital status and breast cancer in younger women. The purpose of this study is to investigate the effect of marital status on diagnosis, and survival of women under the age of 65 with breast cancer. METHODS: The SEER 18 regions database was used to identify women between the ages of 25-64 diagnosed with invasive breast cancer in the years 2004-2009...
December 21, 2016: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28011074/patient-database-analysis-of-fulvestrant-500%C3%A2-mg-in-the-treatment-of-metastatic-breast-cancer-a-european-perspective
#17
Paolo Marchetti, Nicolai Maass, Joseph Gligorov, Karin Berger, Finlay MacDougall, Jukka Montonen, Jan Lewis
INTRODUCTION: Clinical guidelines recommend that patients with hormone receptor (HR)-positive metastatic breast cancer (MBC) should be preferentially treated with endocrine therapy. Fulvestrant (a selective estrogen receptor degrader) is approved for use in these patients following relapse after, or relapse or progression during, antiestrogen therapy. This descriptive study analyzed European treatment patterns for HR-positive MBC in real-world clinical practice. METHODS: The IMS Oncology Analyzer (OA), a retrospective cancer treatment database reporting physician-entered patient case histories, was used to identify records for postmenopausal women with HR-positive MBC from April 1, 2004 to June 30, 2013 in France, Germany, Italy, and Spain...
December 20, 2016: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/27989669/why-are-guidelines-not-followed-in-clinical-practice
#18
EDITORIAL
F Cardoso, A Gennari
No abstract text is available yet for this article.
December 16, 2016: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/27988412/breast-reconstruction-after-mastectomy-a-ten-year-analysis-of-trends-and-immediate-postoperative-outcomes
#19
Nicole Ilonzo, Ashley Tsang, Sara Tsantes, Alison Estabrook, Aye Moe Thu Ma
: The landscape of breast reconstruction has changed significantly. This study assesses trends in type of reconstruction performed after mastectomy and impact on immediate postoperative complications. METHODS: Data for 67,450 patients undergoing mastectomy for breast cancer were analyzed using the National Surgical Quality Improvement Program (NSQIP) database for years 2005-2014. Primary outcomes were wound, nonwound related infections, and bleeding complications...
December 15, 2016: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/27964970/reply-to-barroso-sousa-r-et%C3%A2-al
#20
LETTER
Jacob Garcia, Larry Green, Phuong Khanh Morrow
No abstract text is available yet for this article.
December 10, 2016: Breast: Official Journal of the European Society of Mastology
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