Sang Eok Lee, Dae Hoon Kim, Seung Myeung Son, Song-Yi Choi, Ra Young You, Chan Hyung Kim, Woong Choi, Hun Sik Kim, Yung Ji Lim, Ji Young Han, Hyun Woo Kim, In Jun Yang, Wen-Xie Xu, Sang Jin Lee, Young Chul Kim, Hyo-Yung Yun
Gastric motility is controlled by slow waves. In general, the activation of the ATP-sensitive K+ (KATP ) channels in the smooth muscle opposes the membrane excitability and produces relaxation. Since metabolic inhibition and/or diabetes mellitus are accompanied by dysfunctions of gastric smooth muscle, we examined the possible roles of KATP channels in human gastric motility. We used human gastric corpus and antrum smooth muscle preparations and recorded the mechanical activities with a conventional contractile measuring system...
2020: Journal of Smooth Muscle Research