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American Journal on Addictions

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https://www.readbyqxmd.com/read/28921814/nabilone-pharmacotherapy-for-cannabis-dependence-a-randomized-controlled-pilot-study
#1
Kevin P Hill, Matthew D Palastro, Staci A Gruber, Garrett M Fitzmaurice, Shelly F Greenfield, Scott E Lukas, Roger D Weiss
BACKGROUND AND OBJECTIVES: We assessed the safety, tolerability, and preliminary efficacy of nabilone, a cannabinoid agonist, to treat cannabis dependence. METHODS: Eighteen adults with DSM-IV cannabis dependence were randomized to receive either 2 mg/day of nabilone (n = 10) or placebo (n = 8) for 10 weeks in addition to medication management. Twelve participants, six in each group, completed treatment. The safety and tolerability of nabilone was assessed at each visit...
September 18, 2017: American Journal on Addictions
https://www.readbyqxmd.com/read/28921780/factors-associated-with-attrition-in-substance-using-patients-enrolled-in-an-intensive-outpatient-program
#2
James Mckowen, Nicholas Carrellas, Courtney Zulauf, Emin Nalan Ward, Ronna Fried, Timothy Wilens
BACKGROUND AND OBJECTIVES: Data suggest individuals with substance use disorders (SUD) have high rates of attrition from treatment and exhibit impairments on measures of executive functioning (EF). The primary aim of this pilot study was to investigate if EF is associated with attrition from a 1 month intensive outpatient program (IOP) for SUD, and examine the feasibility of implementing the project. METHODS: Baseline neurocognitive functioning was assessed by the Cambridge Neuropsychological Test Automated Battery (CANTAB) and the self-reported Behavior Rating Inventory of Executive Functioning (BRIEF-A) questionnaire...
September 18, 2017: American Journal on Addictions
https://www.readbyqxmd.com/read/28898494/n-acetylcysteine-in-the-treatment-of-craving-in-substance-use-disorders-systematic-review-and-meta-analysis
#3
Michel Silvio Duailibi, Quirino Cordeiro, Elisa Brietzke, Marcelo Ribeiro, Steve LaRowe, Michael Berk, Alisson Paulino Trevizol
BACKGROUND AND OBJECTIVES: Recent neurobiological evidences along with clinical observations justify the use of N-acetylcysteine (NAC) as a medication for craving. The objective of our study was to assess the evidence of efficacy of NAC for craving in substance use disorders in randomized clinical trials (RCTs). METHODS: Systematic review of the RCTs literature (PROSPERO number 56698) until February, 2017, using MEDLINE, Cochrane Library and clinicaltrials.gov. We included seven RCTs (n = 245); most with small-to-moderate sample sizes...
September 12, 2017: American Journal on Addictions
https://www.readbyqxmd.com/read/28898485/transcranial-magnetic-stimulation-of-the-dorsal-lateral-prefrontal-cortex-inhibits-medial-orbitofrontal-activity-in-smokers
#4
Xingbao Li, Gregory L Sahlem, Bashar W Badran, Lisa M McTeague, Colleen A Hanlon, Karen J Hartwell, Scott Henderson, Mark S George
BACKGROUND AND OBJECTIVE: Several studies have shown that repetitive transcranial magnetic stimulation (rTMS), applied to the dorsolateral prefrontal cortex (DLPFC), can reduce cue-elicited craving in smokers. Currently, the mechanism of this effect is unknown. We used functional magnetic resonance imaging (fMRI) to explore the effect of a single treatment of rTMS on cortical and sub-cortical neural activity in non-treatment seeking nicotine-dependent participants. METHODS: We conducted a randomized, counterbalanced, crossover trial in which participants attended two experimental visits separated by at least 1 week...
September 12, 2017: American Journal on Addictions
https://www.readbyqxmd.com/read/28881065/the-intergenerational-transmission-of-at-risk-problem-gambling-the-moderating-role-of-parenting-practices
#5
Nicki A Dowling, Kerrie A Shandley, Erin Oldenhof, Julia M Affleck, George J Youssef, Erica Frydenberg, Shane A Thomas, Alun C Jackson
BACKGROUND AND OBJECTIVES: Although parenting practices are articulated as underlying mechanisms or protective factors in several theoretical models, their role in the intergenerational transmission of gambling problems has received limited research attention. This study therefore examined the degree to which parenting practices (positive parenting, parental involvement, and inconsistent discipline) moderated the intergenerational transmission of paternal and maternal problem gambling...
September 7, 2017: American Journal on Addictions
https://www.readbyqxmd.com/read/28857330/increased-habenular-connectivity-in-opioid-users-is-associated-with-an-%C3%AE-5-subunit-nicotinic-receptor-genetic-variant
#6
Kaylah Curtis, Humsini Viswanath, Kenia M Velasquez, David L Molfese, Mark J Harding, Eduardo Aramayo, Philip R Baldwin, Elisa Ambrosi, Alok Madan, Michelle Patriquin, B Christopher Frueh, J Christopher Fowler, Thomas R Kosten, David A Nielsen, Ramiro Salas
BACKGROUND AND OBJECTIVES: Opioid use disorder (OUD) is a chronic disorder with relapse based on both desire for reinforcement (craving) and avoidance of withdrawal. The aversive aspect of dependence and relapse has been associated with a small brain structure called the habenula, which expresses large numbers of both opioid and nicotinic receptors. Additionally, opioid withdrawal symptoms can be induced in opioid-treated rodents by blocking not only opioid, but also nicotinic receptors...
August 31, 2017: American Journal on Addictions
https://www.readbyqxmd.com/read/28800182/development-and-preliminary-pilot-evaluation-of-a-brief-tablet-computer-intervention-to-motivate-tobacco-quitline-use-among-smokers-in-substance-use-treatment
#7
Richard A Brown, Jacki Hecht, Erika L Bloom, Haruka Minami, Christopher W Kahler, Ana M Abrantes, Mary E Dubreuil, Alan Gordon, Lawrence H Price, Steven J Ondersma
BACKGROUND AND OBJECTIVES: The majority of individuals in substance use disorder (SUD) treatment also smoke cigarettes; yet, the availability of smoking cessation services in SUD treatment remains limited. In this study, we developed and piloted a brief intervention for smokers in SUD treatment intended to motivate engagement in tobacco quitline treatment (TIME-TQ). METHODS: First, we interviewed 19 smokers in SUD treatment to inform the development of TIME-TQ (Phase 1)...
August 11, 2017: American Journal on Addictions
https://www.readbyqxmd.com/read/28799677/text-message-reminders-for-improving-patient-appointment-adherence-in-an-office-based-buprenorphine-program-a-feasibility-study
#8
Babak Tofighi, Frank Grazioli, Sewit Bereket, Ellie Grossman, Yindalon Aphinyanaphongs, Joshua David Lee
BACKGROUND AND OBJECTIVES: Missed visits are common in office-based buprenorphine treatment (OBOT). The feasibility of text message (TM) appointment reminders among OBOT patients is unknown. METHODS: This 6-month prospective cohort study provided TM reminders to OBOT program patients (N = 93). A feasibility survey was completed following delivery of TM reminders and at 6 months. RESULTS: Respondents reported that the reminders should be provided to all OBOT patients (100%) and helped them to adhere to their scheduled appointment (97%)...
August 11, 2017: American Journal on Addictions
https://www.readbyqxmd.com/read/28782904/role-of-olfactory-reactions-nociception-and-immunoendocrine-shifts-in-addictive-disorders
#9
Elena Masterova, Tatiana Nevidimova, Dariya Savochkina, Valentina Nikitina, Olga Lobacheva, Tamara Vetlugina, Nikolay Bokhan
BACKGROUND AND OBJECTIVES: Addictive pathology is associated with nervous, immune, and endocrine shifts. Meanwhile, the nature of intersystemic relationship lying beneath addictive disorders remains unclear. The purpose of the study was to identify neuroimmunoendocrine markers of addictive disorders in male subjects defining the nature of their interaction. METHODS: The study enrolled 69 subjects aged 18-43 years: 59 males and 10 females divided into those with addictive disorders (n = 39) and conditionally healthy subjects (n = 30)...
August 7, 2017: American Journal on Addictions
https://www.readbyqxmd.com/read/28782900/correlates-of-methamphetamine-use-among-young-iranians-findings-of-a-population-based-survey-in-2013
#10
Nahid Bagheri, Moghaddameh Mirzaee, Yunes Jahani, Mohammad Karamouzian, Hamid Sharifi
INTRODUCTION: Methamphetamine use remains an important public health concern among young people across various international settings. The present study is aimed at investigating the correlates of methamphetamine use among young Iranians within the general population. MATERIALS AND METHODS: This study was carried out in 13 provinces of Iran in 2013. Through multistage sampling, 3,246 young adults (aged 19-29 years) were recruited in the study. Weighted multilevel logistic regression methods were applied to identify the correlates of methamphetamine use...
August 7, 2017: American Journal on Addictions
https://www.readbyqxmd.com/read/28940679/issue-information-toc
#11
(no author information available yet)
No abstract text is available yet for this article.
October 2017: American Journal on Addictions
https://www.readbyqxmd.com/read/28940678/issue-information-editorial-board
#12
(no author information available yet)
No abstract text is available yet for this article.
October 2017: American Journal on Addictions
https://www.readbyqxmd.com/read/28836712/religious-coping-in-patients-with-severe-substance-use-disorders-receiving-acute-inpatient-detoxification
#13
Morgan M Medlock, David H Rosmarin, Hilary S Connery, Margaret L Griffin, Roger D Weiss, Sterling L Karakula, R Kathryn McHugh
BACKGROUND AND OBJECTIVES: Religious coping, one of the most widely studied components of spirituality among psychiatric populations, has rarely been addressed in patients with severe substance use disorders (SUD). The aim of our study was to elucidate whether religious coping is related to symptom expression and mutual-help participation. METHODS: Self-reported religious coping was assessed in individuals sequentially admitted to a private psychiatric hospital for inpatient detoxification...
October 2017: American Journal on Addictions
https://www.readbyqxmd.com/read/28836711/delirium-tremens-and-alcohol-withdrawal-nationally-in-the-veterans-health-administration
#14
David Thomas Moore, Brian Scott Fuehrlein, Robert Alan Rosenheck
BACKGROUND AND OBJECTIVES: Alcohol withdrawal-especially delirium tremens (DT)-is a potentially life-threatening condition. While short-term treatment regimens and factors that predispose to more severe symptomatology have been extensively studied, little attention has been paid to the clinical epidemiology and long-term care of the chronic medical, addictive, psychiatric, and psychosocial problems faced by these patients. METHODS: National Veterans Health Administration data from fiscal year 2012 were examined to identify veterans diagnosed with DT; with withdrawal but not DT (WNDT); and with Alcohol Use Disorder (AUD) but neither DT nor WNDT...
October 2017: American Journal on Addictions
https://www.readbyqxmd.com/read/28834024/nonmedical-versus-medical-marijuana-use-among-three-age-groups-of-adults-associations-with-mental-and-physical-health-status
#15
Namkee G Choi, Diana M DiNitto, Carl Nathan Marti
BACKGROUND AND OBJECTIVE: Given that 29 U.S. states now have laws allowing medical marijuana use, this study examined mental and physical health correlates of medical versus nonmedical marijuana use among three age groups of adults (18-29, 30-49, and 50+). METHODS: Data came from the 2012-2013 National Epidemiologic Survey on Alcohol and Related Conditions (N = 36,309 respondents aged 18+). Logistic regression models were used to examine age group differences in associations of substance use and mental disorders and health conditions with medical versus nonmedical marijuana use...
October 2017: American Journal on Addictions
https://www.readbyqxmd.com/read/28833832/pretreatment-ethyl-glucuronide-levels-predict-response-to-a-contingency-management-intervention-for-alcohol-use-disorders-among-adults-with-serious-mental-illness
#16
Michael Gerard McDonell, Emily Leickly, Sterling McPherson, Jordan Skalisky, Katherine Hirchak, Oladunni Oluwoye, Debra Srebnik, John Michael Roll, Richard Kirkland Ries
BACKGROUND AND OBJECTIVES: This study investigated if pretreatment ethyl glucuronide (EtG) levels corresponding to light (100 ng/mL), heavy (500 ng/mL), and very heavy (1,000 ng/mL) drinking predicted longest duration of alcohol abstinence (LDA) and proportion of EtG-negative urine tests in outpatients receiving a 12-week EtG-based contingency management (CM) intervention for alcohol dependence. METHODS: Participants were 40 adults diagnosed with alcohol use disorders and serious mental illness who submitted up to 12 urine samples for EtG analysis during a 4-week observation period and were then randomized to 12-weeks of CM for alcohol abstinence and addiction treatment attendance...
October 2017: American Journal on Addictions
https://www.readbyqxmd.com/read/28800186/ameliorative-response-to-detoxification-psychotherapy-and-medical-management-in-patients-maintained-on-opioids-for-pain
#17
Molly Belkin, Howard Stephen Reinheimer, Jordan Levy, Brian Johnson
BACKGROUND AND OBJECTIVES: The prevalence of opioid-induced hyperalgesia (OIH) among patients maintained on opioids for chronic non-malignant pain has not been estimated. As a contribution toward establishing its prevalence, we report a case series of opioid maintained patients whose pain tolerance was measured by the cold pressor test at baseline. METHODS: A case series of 117 patients who had undergone detoxification was reviewed retrospectively. Most patients (n = 108) and selected non-addicted support persons who accompanied them (controls; n = 37) had cold pressor time (CPT) assessments at baseline...
October 2017: American Journal on Addictions
https://www.readbyqxmd.com/read/28782902/gambling-involvement-among-native-americans-blacks-and-whites-in-the-united-states
#18
Grace M Barnes, John W Welte, Marie-Cecile O Tidwell
BACKGROUND AND OBJECTIVES: This paper examines risk factors of gambling and problem gambling among racial subgroups in the U.S. population, namely Native Americans and blacks, for whom research data are lacking. METHODS: Findings are based on a large representative general population survey (n = 3,474) of gambling in the U.S. with an oversample of Native Americans (n = 549). Multiple domains were assessed including sociodemographic factors; ecological factors (census-defined neighborhood disadvantage, geocoded density of casinos within 30 miles of respondents' homes, and perceived gambling convenience); impulsivity; and alcohol abuse...
October 2017: American Journal on Addictions
https://www.readbyqxmd.com/read/28677919/prevalence-and-predictors-of-substance-use-disorders-among-homeless-women-seeking-primary-care-an-11-site-survey
#19
Carole Christofk Upshur, Darlene Jenkins, Linda Weinreb, Lillian Gelberg, Elizabeth Aaker Orvek
BACKGROUND AND OBJECTIVES: Homeless women have shown high rates of substance use disorders (SUD), but many studies are more than a decade old, limited in geographic location, or focus only on women living outdoors or in shelters. The purpose of this study was to obtain a more current and representative sample of homeless women and the prevalence and predictors of substance use disorders among women seeking primary care at Health Care for the Homeless clinics across the US. METHODS: Eleven Health Care for the Homeless (HCH) clinics in nine states contributed proportionally to a sample of n = 780 female patients who completed a self-administered survey including demographics, housing history, health, mental health, and drug and alcohol use...
October 2017: American Journal on Addictions
https://www.readbyqxmd.com/read/28324627/hospitalized-opioid-dependent-patients-exploring-predictors-of-buprenorphine-treatment-entry-and-retention-after-discharge
#20
Christina S Lee, Jane M Liebschutz, Bradley J Anderson, Michael D Stein
OBJECTIVES: Few studies have explored predictors of entry into and retention in buprenorphine treatment following linkage from an acute medical hospitalization. METHODS: This secondary analysis of a completed clinical trial focuses on medically hospitalized, opioid-dependent patients (n = 72) who were randomized to an intervention including buprenorphine induction and dose stabilization during hospitalization followed by post-discharge transition to office-based buprenorphine treatment (OBOT)...
October 2017: American Journal on Addictions
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