journal
MENU ▼
Read by QxMD icon Read
search

Journal of Assisted Reproduction and Genetics

journal
https://www.readbyqxmd.com/read/28523409/factors-associated-with-a-poor-prognosis-for-the-ivf-icsi-live-birth-rate-in-women-with-rafs-stage-iii-and-iv-endometriosis
#1
Pauline Roux, Jeanne Perrin, Julien Mancini, Aubert Agostini, Léon Boubli, Blandine Courbiere
PURPOSE: To assess the factors associated with a poor prognosis for a cumulative IVF live birth rate (LBR) in women with stage III and IV endometriosis according to the revised classification of the American Fertility Society (rAFS). METHODS: A retrospective cohort study was conducted between January 1, 2010, and December 31, 2014, in our Reproductive Medicine Center. We analyzed different factors associated with a poor prognosis for a cumulative IVF LBR in women with rAFS stage III and IV endometriosis...
May 18, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28523408/genetics-and-epigenetics-of-varicocele-pathophysiology-an-overview
#2
REVIEW
Viviane Paiva Santana, Cristiana Libardi Miranda-Furtado, Flavia Gaona de Oliveira-Gennaro, Rosana Maria Dos Reis
Varicocele is found in approximately 20% of adults and adolescents and in 19-41% of men seeking treatment for infertility. It is associated with a decrease in sperm count as well as sperm motility and morphology. The currently accepted description of the pathophysiology of varicocele does not explain all its clinical manifestations; therefore, other factors such as genetic and epigenetic changes, associated with the environment, might be involved in causing infertility and decrease in sperm quality. It has been reported that the varicocele-induced deterioration of testicular function is progressive and interferes with fertility; hence, early and efficient assessment of the genetic manifestations in patients would be important for developing future medical interventions...
May 18, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28508227/the-mdm2-promoter-t309g-polymorphism-was-associated-with-preeclampsia-susceptibility
#3
Saeedeh Salimi, Abbas Mohammadpour-Gharehbagh, Mahnaz Rezaei, Mojtaba Sajadian, Batool Teimoori, Atefeh Yazdi, Mojgan Mokhtari, Minoo Yaghmaei
PURPOSE: Preeclampsia (PE) is a hypertensive disorder of pregnancy in which abnormal proliferation and apoptosis of placenta trophoblast has a pivotal role in its pathophysiology. The aim of the current study was to examine the association between Mouse Double Minute 2 (MDM2) T309G and 40 bp insertion/deletion (I/D) polymorphisms and PE risk. METHODS: A case-control study was conducted on 208 PE women and 164 healthy pregnant women matching age, sex, and ethnicity...
May 15, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28508226/erratum-to-introducing-precise-genetic-modifications-into-human-3pn-embryos-by-crispr-cas-mediated-genome-editing
#4
Xiangjin Kang, Wenyin He, Yuling Huang, Qian Yu, Yaoyong Chen, Xingcheng Gao, Xiaofang Sun, Yong Fan
No abstract text is available yet for this article.
May 15, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28502062/significantly-lengthened-telomere-in-granulosa-cells-from-women-with-polycystic-ovarian-syndrome-pcos
#5
Duo Wei, Juanke Xie, Baoli Yin, Haoying Hao, Xiaobing Song, Qi Liu, Cuilian Zhang, Yingpu Sun
PURPOSE: Polycystic ovary syndrome (PCOS) is the most common endocrinopathy among women at reproductive age. However, its etiology remains poorly understood. Recent studies indicated that telomere length was related to PCOS. However, the association between telomere length and PCOS has only been shown in leucocytes and remained controversial across different studies. To clarify the association between telomere length and PCOS, the current study interrogated telomere length not only in leucocytes, but also in follicular granulosa cells, which is essential for folliculogenesis and steroidogenesis...
May 13, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28500451/pregnancy-rates-for-single-embryo-transfer-set-of-day-5-and-day-6-blastocysts-after-cryopreservation-by-vitrification-and-slow-freeze
#6
Leah Kaye, Erica Anspach Will, Alison Bartolucci, John Nulsen, Claudio Benadiva, Lawrence Engmann
PURPOSE: The purpose of this study was to compare clinical and ongoing pregnancy rates in cycles with single embryo transfer (SET) of blastocysts cryopreserved on day 5 or day 6. Our aim was to determine whether day 6 blastocysts perform adequately to recommend SET. METHODS: Retrospective cohort study including 468 transfer cycles for 392 women younger than age 38 undergoing SET at a university-affiliated IVF clinic in the USA. A total of 261 day 5 blastocysts and 207 day 6 blastocysts for frozen-thawed SET between 2010 and 2016 were analyzed...
May 12, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28500450/genetic-variation-in-matrix-metalloproteinase-mmp2-and-mmp9-as-a-risk-factor-for-idiopathic-recurrent-spontaneous-abortions-in-an-indian-population
#7
Deepika Ramu, Vettriselvi Venkatesan, Solomon Franklin Durairaj Paul, Teena Koshy
PURPOSE: Matrix metalloproteinases, MMP2 and MMP9, are found to have an important role during ovulation and pregnancy because of their capacity to degrade components of the extracellular matrix (ECM) thereby facilitating cell migration and angiogenesis. In this respect, the aim of the present study was to evaluate the association of the promoter polymorphisms -1306 C > T and -1562 C/T in MMP2 and MMP9 respectively with couples diagnosed with idiopathic recurrent spontaneous abortions (IRSA)...
May 12, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28497410/could-monopronucleated-icsi-zygotes-be-considered-for-transfer-analysis-through-time-lapse-monitoring-and-pgs
#8
S Mateo, F Vidal, M Parriego, I Rodríguez, V Montalvo, A Veiga, M Boada
PURPOSE: The purpose of this study was to investigate the chromosomal constitution and the developmental potential of intracytoplasmic sperm injection (ICSI) deriving embryos displaying a single pronucleus at the zygote stage. METHODS: Eighty-eight embryos from single pronucleus (1PN) two polar bodies (2PB) ICSI zygotes from 64 preimplantational genetic screening (PGS) cycles (October 2012-December 2014), were retrospectively analyzed. Zygotes were cultured in a time-lapse incubator...
May 11, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28477298/telomere-length-is-short-in-pcos-and-oral-contraceptive-does-not-affect-the-telomerase-activity-in-granulosa-cells-of-patients-with-pcos
#9
Ying Li, Bingbing Deng, Nengyong Ouyang, Ping Yuan, Lingyan Zheng, Wenjun Wang
PURPOSE: Our study aimed to investigate the association of telomerase activity (TA) and telomere length (TL) in granulosa cells (GCs) with IVF outcomes of polycystic ovary syndrome (PCOS) patients, and the effects of oral contraceptive pill (OCP) pretreatment on these two parameters. METHODS: One hundred sixty-three infertile women were enrolled and divided into a PCOS group (n = 65) and a non-PCOS group (n = 98). The PCOS group was further divided into an OCP pretreatment group (n = 35) and a non-OCP pretreatment group (n = 30), a TA <0...
May 6, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28470453/the-effect-of-follicle-size-and-homogeneity-of-follicular-development-on-the-morphokinetics-of-human-embryos
#10
Semra Kahraman, Caroline Pirkevi Cetinkaya, Murat Cetinkaya, Hakan Yelke, Yesim Kumtepe Colakoglu, Melih Aygun, Markus Montag
PURPOSE: Our aim was to investigate follicular size (large, ≥17 mm and small, <17 mm) at the time of OPU and homogeneity of follicular development (homogenous development: follicles being present in a homogenous spread of all sizes; heterogeneous: a predominance of small and large follicles) by analysing the morphokinetics of embryo development. METHODS: In this prospective cohort study, 2526 COCs belonging to 187 patients were cultured to day 5. Embryos were evaluated morphokinetically...
May 4, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28470452/ccdc22-gene-polymorphism-is-associated-with-advanced-stages-of-endometriosis-in-a-sample-of-brazilian-women
#11
Daniela de Oliveira Francisco, Marina de Paula Andres, Bárbara Yasmim Gueuvoghlanian-Silva, Sergio Podgaec, Cintia Fridman
PURPOSE: Based on the assumption that genetic factors are involved in the etiology of endometriosis, this study aimed to investigate the possibility of rs498679 (TLR4 gene), rs1799964 (TNF-α gene), rs3024496 (IL-10 gene), and rs2294021 (CCDC22 gene) polymorphisms being associated with the occurrence of this disease in a sample of Brazilian women. METHODS: We conducted a case-control study with 100 women with histological confirmation of endometriosis (endometriosis group) and 100 women submitted to laparoscopy for benign disorders, in which the absence of endometriosis was confirmed (control group)...
May 4, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28470451/precision-reproductive-medicine-multigene-panel-testing-for-infertility-risk-assessment
#12
REVIEW
Stephen C Collins
The concept of precision medicine relies on a thorough understanding of the consequences of unique features of individual patients, such as environmental exposures and genetic profiles. A key component of implementing individualized care in this paradigm will be improved assessment of genetic risk. Compared with single gene tests, multigene panel testing-which has recently become commercially available for female infertility-offers the possibility of a more comprehensive and efficient risk evaluation. However, as the use of multigene panel testing for breast cancer risk has shown, this approach must be used judiciously to ensure its usefulness in a clinical setting...
May 3, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28466234/the-bovine-embryo-hatches-from-the-zona-pellucida-through-either-the-embryonic-or-abembryonic-pole
#13
Verónica M Negrón-Pérez, Peter J Hansen
PURPOSE: Implantation of the mammalian embryo in the uterus is preceded by escape from the zona pellucida. In some species, hatching from the zona occurs preferentially from one or the other poles of the embryo. The situation for the bovine embryo, in which hatching precedes attachment to the uterus by more than a week, is unclear. The purpose was to describe whether hatching of the bovine embryo from the zona pellucida occurs preferentially from the embryonic or abembryonic pole. METHODS: Bovine blastocysts undergoing hatching were examined by light microscopy (n = 84) and epifluorescence imaging using antibodies for markers of epiblast, hypoblast, and trophectoderm (TE) (n = 26)...
May 3, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28466233/age-related-expression-of-tgf-beta-family-receptors-in-human-cumulus-oophorus-cells
#14
A Ribeiro, C Freitas, L Matos, A Gouveia, F Gomes, J L Silva Carvalho, H Almeida
PURPOSE: During ovarian follicle growth, local cellular interactions are essential for oocyte quality acquisition and successful fertilization. While cumulus cells (CCs) nurture oocytes, they also deliver oocyte-secreted factors (OSFs) that activate receptors on CCs. We hypothesized that disturbance of those interactions contributes to age-related lower reproductive success in women submitted to assisted reproductive technology treatments. METHODS: Women aged 27-48, without recognized personal reproductive disorder, were enrolled in the study and divided in <35- and ≥35-year-old groups...
May 2, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28455755/is-early-embryo-development-as-observed-by-time-lapse-microscopy-dependent-on-whether-fresh-or-frozen-sperm-was-used-for-icsi-a-cohort-study
#15
Jessica Eastick, Christos Venetis, Simon Cooke, Ashleigh Storr, Daisy Susetio, Michael Chapman
PURPOSE: The aim of this study was to compare timings of key events of embryo development from those originating from either fresh or cryopreserved ejaculate sperm using time-lapse technology. METHODS: In this retrospective observational cohort study, time-lapse technology was used to monitor 1927 embryos from 234 women undergoing intracytoplasmic sperm injection (ICSI) and utilizing either fresh (n = 172 cycles) or cryopreserved ejaculate sperm (n = 62 cycles) for insemination were included in the study...
April 29, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28455754/dhea-supplementation-can-result-in-assay-changes-which-may-impact-clinical-decisions-in-ivf
#16
LETTER
Jason Franasiak, Eric Forman, Richard Scott
No abstract text is available yet for this article.
April 29, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28455753/erratum-to-dehydroepiandrosterone-dhea-supplementation-results-in-supraphysiologic-dhea-s-serum-levels-and-progesterone-assay-interference-that-may-impact-clinical-management-in-ivf
#17
Jason M Franasiak, Semara Thomas, Susan Ng, Maria Fano, Andrew Ruiz, Richard T Scott, Eric J Forman
No abstract text is available yet for this article.
April 29, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28455751/national-trends-and-outcomes-of-autologous-in-vitro-fertilization-cycles-among-women-ages-40-years-and-older
#18
Heather Hipp, Sara Crawford, Jennifer F Kawwass, Sheree L Boulet, David A Grainger, Dmitry M Kissin, Denise Jamieson
PURPOSE: The purpose of the study was to describe trends in and investigate variables associated with clinical pregnancy and live birth in autologous in vitro fertilization (IVF) cycles among women ≥40 years. METHODS: We used autologous IVF cycle data from the National ART Surveillance System (NASS) for women ≥40 years at cycle start. We assessed trends in fresh and frozen cycles (n = 371,536) from 1996 to 2013. We reported perinatal outcomes and determined variables associated with clinical pregnancy and live birth in fresh cycles between 2007 and 2013...
April 28, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28432487/sodium-hydrogen-exchanger%C3%A2-expression-in-human-sperm-and-its-relationship-with-semen-parameters
#19
Zhe Zhang, Yuzhuo Yang, Han Wu, Hongliang Zhang, Haitao Zhang, Jiaming Mao, Defeng Liu, Lianming Zhao, Haocheng Lin, Wenhao Tang, Kai Hong, Hui Jiang
PURPOSE: Sperm-specific sodium-hydrogen exchanger (sNHE) is essential to maintain sperm normal function in mice; however, its role in human sperm has not been clarified to date. The aim of this study is to investigate the expression pattern of sNHE in human spermatozoa and its relationship with sperm functional parameters. METHOD: Semen samples from 68 asthenozoospermic and 61 normozoospermic men were analyzed for sperm concentration, motility, and acrosome reaction, and high motile spermatozoa were collected by swim-up method...
April 21, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28429137/women-s-alcohol-consumption-and-cumulative-incidence-of-live-birth-following-in-vitro-fertilization
#20
L E Dodge, S A Missmer, K L Thornton, M R Hacker
OBJECTIVE: The objective of this study was to determine the effect of alcohol consumption on outcomes among women undergoing in vitro fertilization (IVF). DESIGN: This study is a retrospective cohort study. SETTING: This study was performed in a private academically affiliated IVF center. PATIENTS: Patients included women presenting for their first IVF cycle from July 2004 through October 2012. INTERVENTION: Women completed self-administered questionnaires before their first IVF cycle, which included report of usual alcohol consumption...
April 20, 2017: Journal of Assisted Reproduction and Genetics
journal
journal
31004
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"