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Journal of Diabetes and its Complications

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https://www.readbyqxmd.com/read/28533105/prevalence-of-overactive-bladder-and-its-impact-on-quality-of-life-in-1025-patients-with-type-2-diabetes-in-mainland-china
#1
Dongjuan Xu, Jie Gao, Xiaojuan Wang, Liqun Huang, Kefang Wang
AIMS: This study examined the prevalence of overactive bladder (OAB) and investigated the impact of OAB on quality of life (QOL) in patients with type 2 diabetes in Mainland China. METHODS: A total of 1025 patients with type 2 diabetes were surveyed. Patients were grouped into no OAB, dry OAB, and wet OAB groups according to the presence of OAB and urge incontinence. Descriptive analyses, one-way analysis of variance (ANOVA) and multivariable regression models were conducted to assess the prevalence of OAB and the effect of OAB on QOL...
May 10, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/28506691/urinary-lysophopholipids-are-increased-in-diabetic-patients-with-nephropathy
#2
Jean-Sébastien Saulnier-Blache, Eva Feigerlova, Jean Michel Halimi, Pierre Gourdy, Ronan Roussel, Bruno Guerci, Aude Dupuy, Justine Bertrand-Michel, Jean-Loup Bascands, Samy Hadjadj, Joost P Schanstra
Diabetic nephropathy (DN) is a major cause of chronic kidney disease that frequently leads to end stage renal failure. Lysophosphatidic acid (LPA) and lysophosphatidylcholine (LPC) are lysophospholipid mediators shown to accumulate in kidney and to promote renal inflammation and tubulo-interstitial fibrosis in diabetic rodent models. Here we assessed whether LPA and LPC were associated to the development of nephropathy in diabetic human patients. Several molecular species of LPA and LPC were quantified by LC/MS-MS in urine and plasma from type 2 diabetic patients with (cases; n=41) or without (controls, n=41) nephropathy symptoms (micro/macro-albuminuria and eGFR<60ml/min/1...
May 10, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/28479035/erratum-to-prevalence-and-risk-factors-for-diabetic-retinopathy-at-diagnosis-drad-in-patients-recently-diagnosed-with-type-2-diabetes-t2d-or-latent-autoimmune-diabetes-in-the-adult-lada-j-diabetes-complications-30-8-1456-1461
#3
Mats Martinell, Mozhgan Dorkhan, Jan Stålhammar, Petter Storm, Leif Groop, Carin Gustavsson
No abstract text is available yet for this article.
May 3, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/28479034/retraction-notice-to-acarbose-on-insulin-resistance-after-an-oral-fat-load-a-double-blind-placebo-controlled-study
#4
Giuseppe Derosa, Pamela Maffioli, Angela D'Angelo, Elena Fogari, Lucio Bianchi, Arrigo F G Cicero
This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy).
May 3, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/28495421/association-of-aldose-reductase-gene-polymorphism-c-106t-in-susceptibility-of-diabetic-peripheral-neuropathy-among-north-indian-population
#5
Balram Gupta, S K Singh
AIM/HYPOTHESIS: Polymorphism in aldose reductase (ALR) gene at nucleotide C(-106)T (rs759853) in the promoter region is associated with susceptibility to development of diabetic peripheral neuropathy. The aim of this study was to detect the association of the C (-106)T polymorphism of ALR gene and its frequency among patients with type 2 diabetes mellitus with and without peripheral neuropathy. METHODS: The study subjects were divided into three groups. Group I included 356 patients with diabetes having peripheral neuropathy...
April 28, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/28479156/multi-center-feasibility-study-of-microwave-radiometry-thermometry-for-non-invasive-differential-diagnosis-of-arterial-disease-in-diabetic-patients-with-suspected-critical-limb-ischemia
#6
Stavros Spiliopoulos, Vasiliki Theodosiadou, Nikolaos Barampoutis, Konstantinos Katsanos, Periklis Davlouros, Lazaros Reppas, Panagiotis Kitrou, Konstantinos Palialexis, Chrysostomos Konstantos, Elias Siores, Dimitrios Alexopoulos, Dimitris Karnabatidis, Elias Brountzos
AIMS: Diagnosis of vascular involvement in diabetic foot ulceration (DFU) remains challenging. We conducted a proof of concept study to investigate the feasibility of microwave radiometry (MWR) thermometry for non-invasive differential diagnosis of critical limb ischemia (CLI) in subjects with DFU. METHODS: This prospective, multi-center, study included 80 participants, divided into four groups (group N: normal control subjects; group DN: participants with diabetes and verified neuropathic ulcers without vascular involvement; group DC: participants with diabetes and CLI and group NDC: participants with CLI without diabetes)...
April 28, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/28479154/can-sglt-2-inhibitors-resolve-the-heart-failure-burden-of-diabetes-mellitus-is-it-empaglifozin-or-the-class
#7
EDITORIAL
Diethelm Tschöpe
No abstract text is available yet for this article.
April 27, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/28483335/the-effect-of-vitamin-d-supplementation-on-glucose-metabolism-in-type-2-diabetes-mellitus-a-systematic-review-and-meta-analysis-of-intervention-studies
#8
Clare J Lee, Geetha Iyer, Yang Liu, Rita R Kalyani, N'Dama Bamba, Colin B Ligon, Sanskriti Varma, Nestoras Mathioudakis
AIMS: We aimed to assess whether vitamin D supplementation improves glucose metabolism in adults with type 2 diabetes. METHODS: PubMed and Cochrane database were searched up to July 1st 2016 for randomized controlled trials that assessed the relationship between vitamin D supplementation and glucose metabolism (change in hemoglobin A1C (HbA1C) and fasting blood glucose (FBG)) among adults with type 2 diabetes. RESULTS: Twenty nine trials (3324 participants) were included in the systematic review...
April 21, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/28476567/dietary-intake-and-risk-of-non-severe-hypoglycemia-in-adolescents-with-type-1-diabetes
#9
Victor W Zhong, Jamie L Crandell, Christina M Shay, Penny Gordon-Larsen, Stephen R Cole, Juhaeri Juhaeri, Anna R Kahkoska, David M Maahs, Michael Seid, Gregory P Forlenza, Elizabeth J Mayer-Davis
AIMS: To determine the association between dietary intake and risk of non-severe hypoglycemia in adolescents with type 1 diabetes. METHODS: Type 1 adolescents from a randomized trial wore a blinded continuous glucose monitoring (CGM) system at baseline for one week in free-living conditions. Dietary intake was calculated as the average from two 24-h dietary recalls. Non-severe hypoglycemia was defined as having blood glucose <70mg/dL for ≥10min but not requiring external assistance, categorized as daytime and nocturnal (11PM-7AM)...
April 20, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/28522035/comorbid-depression-and-diabetes-how-can-we-improve-adherence
#10
EDITORIAL
Kristy Iglay, Larry Radican, Swapnil Rajpathak
No abstract text is available yet for this article.
April 18, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/28499960/association-between-dipstick-hematuria-and-decline-in-estimated-glomerular-filtration-rate-among-japanese-patients-with-type-2-diabetes-a-prospective-cohort-study-diabetes-distress-and-care-registry-at-tenri-ddcrt-14
#11
Tsuyoshi Mashitani, Yasuaki Hayashino, Shintaro Okamura, Masako Kitatani, Miyuki Furuya, Tadao Iburi, Satoru Tsujii, Hitoshi Ishii
AIMS: To assess the association between dipstick hematuria and estimated glomerular filtration rate (eGFR) decline in Japanese patients with type 2 diabetes. METHODS: Longitudinal data were obtained from 3068 Japanese patients with type 2 diabetes. To assess the independent association between dipstick hematuria and eGFR decline, we used Cox proportional hazard model adjusted for potential confounders. RESULTS: Median follow-up period was 699...
April 18, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/28487124/concordance-the-hemoglobin-glycation-index-with-glycation-gap-using-glycated-albumin-in-patients-with-type-2-diabetes
#12
Mee Kyoung Kim, Jee Sun Jeong, Hyuk-Sang Kwon, Ki Hyun Baek, Ki-Ho Song
BACKGROUND: The hemoglobin glycation index (HGI) is an index of differences in the glycation of hemoglobin according to blood glucose level. The glycation gap (G-gap) is an empiric measure of the extent of disagreement between hemoglobin A1C (HbA1C) and glycated albumin (GA). The aim of this study was to investigate the extent of agreement between the HGI and G-gap with respect to GA level, and to elucidate factors related to a high HGI. METHOD: Data were obtained from 105 patients with type 2 diabetes, and fasting blood glucose (FBG), HbA1c, and GA values were measured simultaneously...
April 18, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/28473187/serum-rbp4-and-ckd-association-with-insulin-resistance-and-lipids
#13
Maria Alice M Domingos, Márcia Queiroz, Paulo Andrade Lotufo, Isabela Judith Benseñor, Silvia Maria de Oliveira Titan
OBJECTIVE: Serum RBP4 is new adipokine and it has been related to insulin resistance and diabetes risk in animal and clinical studies. However, there is controversy on this relationship among CKD patients. In this study, we evaluated the association of serum RBP4 with insulin resistance and cardiovascular risk factors in CKD. METHODS: Baseline data from the PROGREDIR Study (Sao Paulo, Brazil) comprising 454 participants (mainly stages 3 and 4) was analyzed. RESULTS: In univariable analysis, RBP4 was inversely related to renal function, age and HDL, and positively related to other lipids, insulinemia, HOMA, glycemia, albumin, phosphorus and right hepatic lobe diameter...
April 18, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/28465145/energy-sensing-pathways-bridging-type-2-diabetes-and-colorectal-cancer
#14
REVIEW
Juhong Yang, Reiko Nishihara, Xuehong Zhang, Shuji Ogino, Zhi Rong Qian
The recently rapid increase of obesity and type 2 diabetes mellitus has caused great burden to our society. A positive association between type 2 diabetes and risk of colorectal cancer has been reported by increasing epidemiological studies. The molecular mechanism of this connection remains elusive. However, type 2 diabetes may result in abnormal carbohydrate and lipid metabolism, high levels of circulating insulin, insulin growth factor-1, and adipocytokines, as well as chronic inflammation. All these factors could lead to the alteration of energy sensing pathways such as the AMP activated kinase (PRKA), mechanistic (mammalian) target of rapamycin (mTOR), SIRT1, and autophagy signaling pathways...
April 13, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/28462893/cost-effectiveness-of-gastric-band-surgery-for-overweight-but-not-obese-adults-with-type-2-diabetes-in-the-u-s
#15
John M Wentworth, Kim M Dalziel, Paul E O'Brien, Paul Burton, Frackson Shaba, Philip M Clarke, Neda Laiteerapong, Wendy A Brown
AIM: To determine the cost-effectiveness of gastric band surgery in overweight but not obese people who receive standard diabetes care. METHOD: A microsimulation model (United Kingdom Prospective Diabetes Study outcomes model) was used to project diabetes outcomes and costs from a two-year Australian randomized trial of gastric band (GB) surgery in overweight but not obese people (BMI 25 to 30kg/m(2)) on to a comparable population of U.S. adults from the National Health and Nutrition Examination Survey (N=254)...
April 13, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/28457703/diabetic-complications-do-not-hamper-improvement-of-health-related-quality-of-life-over-the-course-of-treatment-of-diabetic-foot-ulcers-the-eurodiale-study
#16
Volkert Siersma, Hanne Thorsen, Per E Holstein, Marleen Kars, Jan Apelqvist, Edward B Jude, Alberto Piaggesi, Karel Bakker, Michael Edmonds, Alexandra Jirkovská, Didac Mauricio, Heinrich Reike, Maximilian Spraul, Luigi Uccioli, Vilma Urbancic, Kristien van Acker, Jeff van Baal, Nicolaas C Schaper
AIMS: Diabetic complications, and in particular diabetic foot ulcers (DFUs), are associated with low health-related quality of life (HRQoL). We evaluated whether the presence of diabetic complications also influenced the improvement of HRQoL during DFU treatment. METHODS: 1088 patients presenting for DFU treatment at the centers participating in the Eurodiale study were followed prospectively up to one year. HRQoL was measured both at presentation and after healing or at end of follow up, using EQ-5D: a standardized instrument consisting of five domains and a summary index...
April 13, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/28456356/the-relationship-between-right-ventricular-deformation-and-heart-rate-variability-in-asymptomatic-diabetic-patients
#17
Marijana Tadic, Vladan Vukomanovic, Cesare Cuspidi, Jelena Suzic-Lazic, Biljana Pencic-Popovic, Jana Radojkovic, Rade Babic, Vera Celic
OBJECTIVE: To investigate heart rate variability (HRV) and right ventricular (RV) remodeling in asymptomatic diabetic patients, as well as the relationship between HRV indices and RV structure, function and deformation. METHOD: This cross-sectional study included 59 asymptomatic patients with type 2 diabetes and 45 healthy controls without cardiovascular risk factors. All study subjects underwent 24-h Holter monitoring, laboratory analyses and complete two-dimensional echocardiography examination (2DE)...
April 13, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/28462892/effect-of-weight-reductions-on-estimated-kidney-function-post-hoc-analysis-of-two-randomized-trials
#18
Bernt Johan von Scholten, Melanie J Davies, Frederik Persson, Tine W Hansen, Sten Madsbad, Lars Endahl, Cecilie H Jepsen, Peter Rossing
AIMS: Weight loss-induced serum creatinine reduction may increase creatinine-based estimated glomerular filtration rate (eGFR) producing incorrect estimates of kidney function. We investigated whether weight changes in the SCALE program with liraglutide 3.0mg were associated with changes in serum creatinine. METHODS: Post hoc analysis of two 56-week, randomized, double-blind trials: SCALE Obesity and Prediabetes (n=3731, without type 2 diabetes [T2D], randomized [2:1] to liraglutide 3...
April 11, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/28462891/predicting-the-6-month-risk-of-severe-hypoglycemia-among-adults-with-diabetes-development-and-external-validation-of-a-prediction-model
#19
Emily B Schroeder, Stan Xu, Glenn K Goodrich, Gregory A Nichols, Patrick J O'Connor, John F Steiner
AIMS: To develop and externally validate a prediction model for the 6-month risk of a severe hypoglycemic event among individuals with pharmacologically treated diabetes. METHODS: The development cohort consisted of 31,674 Kaiser Permanente Colorado members with pharmacologically treated diabetes (2007-2015). The validation cohorts consisted of 38,764 Kaiser Permanente Northwest members and 12,035 HealthPartners members. Variables were chosen that would be available in electronic health records...
April 11, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/28433447/impaired-fasting-glucose-predicts-the-development-of-hypertension-over-6years-in-female-adults-results-from-the-rural-chinese-cohort-study
#20
Yang Zhao, Haohang Sun, Bingyuan Wang, Ming Zhang, Xinping Luo, Yongcheng Ren, Junmei Zhou, Chengyi Han, Chongjian Wang, Linlin Li, Lu Zhang, Chao Pang, Lei Yin, Tianping Feng, Jingzhi Zhao, Dongsheng Hu
AIMS: To investigate whether impaired fasting glucose (IFG) is an independent risk factor for incident hypertension in a rural Chinese population. METHODS: We selected 9583 eligible participants 18 to 75years old, who were without hypertension and diabetes at baseline (from 2007 to 2008) and were from a rural area in the middle of China. Concentration of fasting glucose at baseline was assessed in quartiles to predict hypertension risk by gender. Odds ratios (ORs) and 95% confidence intervals (CIs) for IFG (fasting glucose of 100 to 125mg/dl) associated with hypertension were estimated by logistic regression models...
April 11, 2017: Journal of Diabetes and its Complications
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