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Surgery Today

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https://www.readbyqxmd.com/read/29222669/the-preoperative-hba1c-level-is-an-independent-prognostic-factor-for-the-postoperative-survival-after-resection-of-non-small-cell-lung-cancer-in-elderly-patients
#1
Makoto Motoishi, Satoru Sawai, Tetsuo Hori, Naoki Yamashita
PURPOSE: The aim of this study was to investigate the influence of a history of diabetes mellitus (DM) and the glycated hemoglobin (HbA1c) level on the survival in patients who underwent complete resection for non-small cell lung cancer (NSCLC). METHODS: Of the patients who underwent complete resection for NSCLC between 2007 and 2015, 468 were classified into DM (who were currently taking medication for DM) and no DM groups as well as into high HbA1c (≥ 6.5) and normal HbA1c (< 6...
December 8, 2017: Surgery Today
https://www.readbyqxmd.com/read/29214351/regenerative-medicine-for-the-esophagus
#2
REVIEW
Kengo Kanetaka, Shinichiro Kobayashi, Susumu Eguchi
Advances in tissue engineering techniques have made it possible to use human cells as biological material. This has enabled pharmacological studies to be conducted to investigate drug effects and toxicity, to clarify the mechanisms underlying diseases, and to elucidate how they compensate for impaired organ function. Many researchers have tried to construct artificial organs using these techniques, but none has succeeded in growing a whole organ. Unlike other digestive organs with complicated functions, such as the processing and absorption of nutrients, the esophagus has the relatively simple function of transporting content, which can be replicated easily by a substitute...
December 6, 2017: Surgery Today
https://www.readbyqxmd.com/read/29185053/acknowledgment-to-reviewers
#3
(no author information available yet)
No abstract text is available yet for this article.
November 28, 2017: Surgery Today
https://www.readbyqxmd.com/read/29170824/an-analysis-of-the-risk-factors-of-anastomotic-stricture-after-esophagectomy
#4
Koji Tanaka, Tomoki Makino, Makoto Yamasaki, Takahiko Nishigaki, Yasuhiro Miyazaki, Tsuyoshi Takahashi, Yukinori Kurokawa, Kiyokazu Nakajima, Shuji Takiguchi, Masaki Mori, Yuichiro Doki
PURPOSE: Anastomotic stricture after esophagectomy is a major cause of long-term morbidity and a poor quality of life. The aim of this study was to identify the risk factors for the development of anastomotic stricture after esophagectomy. METHODS: The study subjects were 213 patients who underwent esophagectomy for squamous cell carcinoma of the esophagus between 2012 and 2014. Anastomotic stricture was defined as stenosis at the site of anastomosis that required endoscopic dilation...
November 23, 2017: Surgery Today
https://www.readbyqxmd.com/read/29134500/systematic-review-of-the-feasibility-and-future-of-laparoscopic-liver-resection-for-difficult-lesions
#5
REVIEW
Kenichiro Araki, Norio Kubo, Akira Watanabe, Hiroyuki Kuwano, Ken Shirabe
Laparoscopic liver resection (LLR) is now performed widely, but is difficult to accomplish in some anatomical locations, such as the posterosuperior segments (S7 and S8) and caudate lobe (S1). An international survey revealed that lesions in these locations are less frequently indicated for LLR than those in other segments. Recent reports from experienced centers document several case series and present technical tips for treating such lesions. The lateral approach using intercostal (transdiaphragmatic) trocars was reported to be useful for lesions in the posterosuperior segments with a semi- to full-decubitus position...
November 13, 2017: Surgery Today
https://www.readbyqxmd.com/read/29124429/what-factors-determine-the-survival-of-patients-with-an-acute-exacerbation-of-interstitial-lung-disease-after-lung-cancer-resection
#6
Masahiro Miyajima, Atsushi Watanabe, Toshihiko Sato, Satoshi Teramukai, Masahito Ebina, Kazuma Kishi, Yukihiko Sugiyama, Haruhiko Kondo, Satoru Kobayashi, Yutaka Takahashi, Hiroyuki Ito, Ryoji Yamamoto, Shigeki Sawada, Hideki Fujimori, Kazunori Okabe, Jun Arikura, Yasushi Shintani, Hiroshige Nakamura, Shinichi Toyooka, Tohru Hasumi, Takehiro Watanabe, Yoshinobu Hata, Hisashi Iwata, Minoru Aoki, Kazuhito Funai, Shuhei Inoue, Osamu Kawashima, Tomohiko Iida, Hiroshi Date
PURPOSES: Acute exacerbation of interstitial pneumonia (AEIP) is a leading cause of death after lung cancer resection in patients with interstitial lung disease. METHODS: We retrospectively analyzed 1763 patients with non-small cell lung cancer with a clinical diagnosis of interstitial lung disease (ILD) who underwent lung cancer resection between 2000 and 2009 at 61 hospitals in Japan. AEIP occurred in 164 of 1763 (9.3%) patients with a mortality rate of 43.9% (72/164)...
November 9, 2017: Surgery Today
https://www.readbyqxmd.com/read/29110090/assessing-the-economic-advantage-of-laparoscopic-vs-open-approaches-for-colorectal-cancer-by-a-propensity-score-matching-analysis
#7
Hiromitsu Hayashi, Nobuyuki Ozaki, Katsuhiro Ogawa, Yoshiaki Ikuta, Hideyuki Tanaka, Kenichi Ogata, Koichi Doi, Hiroshi Takamori
PURPOSES: This study investigated the surgical outcomes and potential economic advantage of open vs. laparoscopic surgery for colorectal cancer using a propensity score matching analysis. METHODS: We examined the surgical and economic outcomes of patients undergoing laparoscopic (N = 127) and open surgery (N = 253) for colorectal cancer and then compared these outcomes in two groups (N = 103 each) using a propensity score matching analysis. RESULTS: Compared to open surgery, the laparoscopic approach was associated with a significantly lower overall morbidity rate (14 vs...
November 7, 2017: Surgery Today
https://www.readbyqxmd.com/read/29110089/impact-of-surgical-treatment-after-sorafenib-therapy-for-advanced-hepatocellular-carcinoma
#8
Hideaki Takeyama, Toru Beppu, Takaaki Higashi, Takayoshi Kaida, Kota Arima, Katsunobu Taki, Katsunori Imai, Hidetoshi Nitta, Hiromitsu Hayashi, Shigeki Nakagawa, Hirohisa Okabe, Daisuke Hashimoto, Akira Chikamoto, Takatoshi Ishiko, Motohiko Tanaka, Yutaka Sasaki, Hideo Baba
BACKGROUND: For advanced hepatocellular carcinoma (HCC), surgical treatment after sorafenib induction has rarely been reported. We examined the survival benefit of additional surgical treatment in sorafenib-treated patients. METHODS: Thirty-two advanced HCC patients were given sorafenib from July 2009 to July 2012, and we statistically analyzed the relevant predictive factors of the long-term survival. The institutional review board of Kumamoto University Hospital approved this study (Approval number 1038)...
November 7, 2017: Surgery Today
https://www.readbyqxmd.com/read/29101474/correction-to-human-cd200-suppresses-macrophage-mediated-xenogeneic-cytotoxicity-and-phagocytosis
#9
Rieko Sakai, Akira Maeda, Thuy-Vy Choi, Pei-Chi Lo, Patmika Jiaravuthisan, Afifah Mod Shabri, Han-Tang Wang, Rei Matsuura, Tasuku Kodama, Hiroshi Eguchi, Hiroomi Okuyama, Shuji Miyagawa
In the original publication, the fifth author name was erroneously published as "Patmika Jiaravuthiasan". The correct author name should read as, "Patmika Jiaravuthisan". The original article was corrected.
November 3, 2017: Surgery Today
https://www.readbyqxmd.com/read/29075927/effects-of-the-concentration-of-digestive-surgical-operations-in-regional-japan
#10
Takefumi Kitazawa, Kunichika Matsumoto, Shigeru Fujita, Kanako Seto, Yinghui Wu, Takayoshi Nagahama, Tomonori Hasegawa
PURPOSE: The purpose of this study was to investigate the relationship between the concentration of digestive system surgery and outcomes at a regional level in Japan, using time-series data. METHODS: We used nationwide data from 2008 to 2013, and analyzed the ten most common surgical procedures. The unit of analysis was secondary medical areas (SMAs), which cover several municipalities and provide medical services for common diseases. The concentration of surgery in these areas was measured using the Herfindahl-Hirschman Index (HHI) and the relationship between the concentration of surgery and length of stay in hospital (LOS) was analyzed, in accordance with surgical difficulty...
October 26, 2017: Surgery Today
https://www.readbyqxmd.com/read/29063371/prognostic-significance-of-the-preoperative-neutrophil-to-lymphocyte-ratio-for-complete-resection-of-thymoma
#11
Masahiro Yanagiya, Jun-Ichi Nitadori, Kazuhiro Nagayama, Masaki Anraku, Masaaki Sato, Jun Nakajima
PURPOSE: The preoperative peripheral neutrophil-to-lymphocyte ratio (NLR) is associated with a poor prognosis for various cancers. We evaluated the prognostic role of the preoperative NLR in patients with thymoma. METHODS: We reviewed the medical records of 254 patients who underwent resection of thymic epithelial tumors at our institution. Patients were excluded if they had received steroid therapy, neoadjuvant therapy, or incomplete resection, or if they had thymic carcinoma or Good's syndrome, recurrence of thymoma, or missing data...
October 23, 2017: Surgery Today
https://www.readbyqxmd.com/read/29052783/anatomical-study-of-the-left-superior-mediastinal-lymphatics-for-tracheal-branches-of-left-recurrent-laryngeal-nerve-preserving-mediastinoscope-assisted-surgery-in-esophageal-cancer
#12
Yutaka Nakajima, Yutaka Tokairin, Yasuaki Nakajima, Kenro Kawada, Kagami Nagai, Kumiko Yamaguchi, Keiichi Akita, Tatsuyuki Kawano
PURPOSE: Curative treatment of esophageal cancer requires meticulous superior mediastinal lymphadenectomy, in addition to esophagectomy, because superior mediastinal lymph node metastases are common in esophageal cancer. When preserving the tracheal branches of the left recurrent laryngeal nerve (RLN), good anatomical understanding is required for confirmation of the positional relationships between the courses of lymphatic vessels, lymph node distribution, and the left RLN and its tracheal branches...
October 20, 2017: Surgery Today
https://www.readbyqxmd.com/read/29052006/risk-factors-for-and-the-prevention-of-acute-kidney-injury-after-abdominal-surgery
#13
REVIEW
Yongbo An, Kai Shen, Yingjiang Ye
Postoperative acute kidney injury in patients undergoing abdominal surgery is not rare and often results in bad outcomes for patients. The incidence of postoperative acute kidney injury is hard to evaluate reliably due to its non-unified definitions in different studies. Risk factors for acute kidney injury specific to abdominal surgery include preoperative renal insufficiency, intraabdominal hypertension, blood transfusion, bowel preparation, perioperative dehydration, contrast agent and nephrotoxic drug use...
October 19, 2017: Surgery Today
https://www.readbyqxmd.com/read/29043453/serum-carbohydrate-antigen-125-is-a-significant-prognostic-marker-in-patients-with-unresectable-advanced-or-recurrent-gastric-cancer
#14
Tsutomu Namikawa, Yasuhiro Kawanishi, Kazune Fujisawa, Eri Munekage, Jun Iwabu, Masaya Munekage, Hiromichi Maeda, Hiroyuki Kitagawa, Michiya Kobayashi, Kazuhiro Hanazaki
PURPOSE: We evaluated the diagnostic and prognostic value of three tumor markers: carcino-embryonic antigen (CEA), carbohydrate antigen 19-9 (CA19-9), and carbohydrate antigen 125 (CA125), in the pretreatment serum of patients with unresectable advanced or recurrent gastric cancer. METHODS: The subjects of this retrospective analysis were 245 patients with unresectable advanced or recurrent gastric cancer diagnosed at Kochi Medical School between 2007 and 2015. We ascertained the sensitivity of CEA, CA19-9, and CA125 to identify a certain survival time and then evaluated the relative prognosis of the patients...
October 17, 2017: Surgery Today
https://www.readbyqxmd.com/read/29027629/combined-analysis-of-the-preoperative-and-postoperative-prognostic-nutritional-index-offers-a-precise-predictor-of-the-prognosis-of-patients-with-gastric-cancer
#15
Yuki Murakami, Hiroaki Saito, Yusuke Kono, Yuji Shishido, Hirohiko Kuroda, Tomoyuki Matsunaga, Yoji Fukumoto, Tomohiro Osaki, Keigo Ashida, Yoshiyuki Fujiwara
PURPOSE: The prognostic nutritional index (PNI) is considered useful for predicting the prognosis of patients with gastric cancer (GC). This retrospective study investigated the relationship between both the pre- and postoperative PNI and the prognosis of GC patients. METHODS: The subjects of this study were 254 patients who underwent curative surgery for histopathologically diagnosed GC. RESULTS: Patients were divided according to their pre- and postoperative PNI as follows: preoperative PNI of ≥ 52 (pre-PNI(High)), preoperative PNI of < 52 (pre-PNI(Low)), postoperative PNI of ≥ 49 (post-PNI(High)), and postoperative PNI of < 49 (pre-PNI(Low))...
October 12, 2017: Surgery Today
https://www.readbyqxmd.com/read/29027585/the-features-of-adipose-derived-stem-cells-in-patients-with-inflammatory-bowel-diseases
#16
Tsunekazu Mizushima, Tadafumi Fukata, Hiroshi Takeyama, Hidekazu Takahashi, Naotsugu Haraguchi, Junichi Nishimura, Taishi Hata, Chu Matsuda, Hirofumi Yamamoto, Yuichiro Doki, Masaki Mori
PURPOSE: The treatment outcomes for inflammatory bowel disease (IBD) have been improving, but the development of better therapies is needed. Stem cell therapy is promising, but little is known about the differences in adipose-derived stem cells (ADSCs) between IBD patients and healthy individuals. METHODS: ADSCs were isolated from subcutaneous adipose tissue (SAT) in IBD (Crohn's disease, 3; ulcerative colitis, 2) and non-IBD (colorectal cancer, 5; breast cancer, 1) patients...
October 12, 2017: Surgery Today
https://www.readbyqxmd.com/read/29027010/oxidized-regenerated-cellulose-induces-pleural-thickening-in-patients-with-pneumothorax-possible-involvement-of-the-mesothelial-mesenchymal-transition
#17
Hiroki Ebana, Takuo Hayashi, Keiko Mitani, Etsuko Kobayashi, Toshio Kumasaka, Teruaki Mizobuchi, Masatoshi Kurihara, Fumiyuki Takahashi, Kazuhisa Takahashi, Kuniaki Seyama
PURPOSE: The pleural covering technique, i.e., wrapping a part of or the entire surface of the lung with oxidized regenerative cellulose (ORC), reinforces visceral pleura through pleural thickening for patients with pneumothorax and cystic lung diseases. However, it remains undetermined how ORC induces pleural thickening. METHODS: A histopathological examination was performed for lung specimens from patients who had recurrent pneumothoraces after pleural covering and re-operation (n = 5)...
October 12, 2017: Surgery Today
https://www.readbyqxmd.com/read/28993997/evaluation-of-the-prognostic-factors-in-patients-with-pt3n0-or-pt1n2-3-gastric-cancer-a-single-institutional-retrospective-cohort-study
#18
Mitsumi Terada, Takahiro Kinoshita, Akio Kaito, Shizuki Sugita, Masahiro Watanabe, Ryuichi Hayashi
PURPOSE: The impact of adjuvant chemotherapy on the survival of patients with the pT3N0/pT1N2-3 subset of Stage II gastric cancer is unclear. The aim of this study was to evaluate the survival rate of pT3N0/pT1N2-3 patients who were treated by surgery alone and to identify a high-risk group within this cohort. METHODS: A total of 258 patients with pT3N0/pT1N2-3 gastric cancer who underwent gastrectomy alone in our hospital between January 1992 and December 2012 were enrolled in the present study...
October 9, 2017: Surgery Today
https://www.readbyqxmd.com/read/28993920/laparoscopic-lymph-node-dissection-around-the-inferior-mesenteric-artery-for-left-sided-colon-and-rectal-cancer
#19
Hidekazu Takahashi, Naotsugu Haraguchi, Junichi Nishimura, Taishi Hata, Chu Matsuda, Hirofumi Yamamoto, Tsunekazu Mizushima, Yuichiro Doki, Masaki Mori
Lymph node dissection is a critical part of surgery for colorectal cancer. Japanese D3 and complete mesocolic excision are two unique principles for lymph node dissection in colorectal cancer. Laparoscopic surgery magnifies the targets and provides insight about the micro-anatomy through high-quality, high-definition imaging, which benefits the surgeon. Although laparoscopic colorectal resection is feasible, there is no universal procedure. We describe in detail the anatomy viewed during lymph node dissection around the inferior mesenteric artery...
October 9, 2017: Surgery Today
https://www.readbyqxmd.com/read/28993901/collagen-gel-droplet-embedded-culture-drug-sensitivity-test-for-adjuvant-chemotherapy-after-complete-resection-of-non-small-cell-lung-cancer
#20
Masayoshi Inoue, Hajime Maeda, Yukiyasu Takeuchi, Kenjiro Fukuhara, Yasushi Shintani, Yasunobu Funakoshi, Soichiro Funaki, Takashi Nojiri, Takashi Kusu, Hidenori Kusumoto, Toru Kimura, Meinoshin Okumura
PURPOSE: We conducted a prospective clinical study to individualize adjuvant chemotherapy after complete resection of non-small-cell lung cancer (NSCLC), based on the drug sensitivity test. METHODS: Patients with resectable c-stage IB-IIIA NSCLC were registered between 2005 and 2010. We performed the collagen gel droplet-embedded culture drug sensitivity test (CD-DST) on a fresh surgical specimen to assess in vitro chemosensitivity and evaluated the prognostic outcome after adjuvant chemotherapy with carboplatin/paclitaxel based on the CD-DST...
October 9, 2017: Surgery Today
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