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https://www.readbyqxmd.com/read/30626848/the-early-diagnosis-of-endophthalmitis-due-to-group-b-streptococcus-infective-endocarditis-and-its-clinical-course-a-case-report-and-literature-review
#1
Yutaka Aoyama, Yusuke Oba, Satoshi Hoshide, Yusuke Arai, Takahiro Komori, Tomoyuki Kabutoya, Kazuomi Kario
A 68-year-old Japanese man was admitted to our hospital with right eye pain, a sudden worsening of his eyesight, and a fever. He was diagnosed with endogenous bacterial endophthalmitis due to infectious endocarditis (IE) of Group B Streptococcus (GBS) on the day of admission. He recovered systemically, but his right eye became phthisical only with the administration of antibiotics. We conducted a review of the reported cases of IE caused by GBS complicated with endogenous bacterial endophthalmitis. IE should be considered when an undetermined etiology of endogenous endophthalmitis is encountered...
January 10, 2019: Internal Medicine
https://www.readbyqxmd.com/read/30626847/ivc-filter-perforation-through-the-duodenum
#2
Takashi Hongo, Ryoichi Harada, Akiko Fujiwara, Toshifumi Fujiwara
No abstract text is available yet for this article.
January 10, 2019: Internal Medicine
https://www.readbyqxmd.com/read/30626846/a-diagnostically-challenging-case-of-autoimmune-pancreatitis-due-to-contamination-of-the-pathological-specimen-with-early-gastric-cancer
#3
Mina Morino, Masanari Sekine, Keita Matsumoto, Hitomi Kashima, Yudai Koito, Takaya Miura, Yuko Takahashi, Rumiko Tsuboi, Takehiro Ishii, Shuhei Yoshikawa, Haruka Ohtake, Junichi Fujiwara, Takeshi Uehara, Kazuhito Yuhashi, Takeharu Asano, Satohiro Matsumoto, Hiroyuki Miyatani, Akira Tanaka, Hirosato Mashima
A 73-year-old man with worsened diabetes underwent abdominal computed tomography and was diagnosed with localized enlargement of the pancreatic tail. Based on the suspicion of autoimmune pancreatitis, endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) was performed. A cytologic examination showed findings suggestive of adenocarcinoma. Due to discrepancies between the imaging and pathological findings, esophago-gastro-duodenoscopy was performed. An extensive early gastric cancer lesion was detected in the posterior wall of the gastric corpus...
January 10, 2019: Internal Medicine
https://www.readbyqxmd.com/read/30626845/venous-aneurysm-of-the-jejunum
#4
Kenta Kumagai, Masato Yoshioka, Naohiko Otsuka, Yuzo Yamamoto
No abstract text is available yet for this article.
January 10, 2019: Internal Medicine
https://www.readbyqxmd.com/read/30626844/a-rare-cause-of-pneumoperitoneum-pictures-in-clinical-medicine
#5
Khay-Seng Soh, Po-Wen Lin, Te-Chun Shen
No abstract text is available yet for this article.
January 10, 2019: Internal Medicine
https://www.readbyqxmd.com/read/30626843/primary-synovial-sarcoma-of-the-mediastinum-with-long-term-follow-up
#6
Hiroaki Kanemura, Naoki Nishimura, Toru Bando, Yuya Ishikawa, Fumitsugu Kojima, Taisuke Mori, Koyu Suzuki, Tomohide Tamura
Chest radiography showed a right posterior mass on the mediastinum of an 84-year-old woman. The mass had been growing gradually for four years. Surgical excision was performed, and a pathological examination found the mass to be consistent with primary synovial sarcoma (SS) of the mediastinum. To our knowledge, this is a rare case in which follow-up imaging was able to be performed over a period of four years. This disease is aggressive, and its early diagnosis is key to achieving a cure. It is important to consider primary SS in the differential diagnosis of a primary intra-thoracic tumor, even if the tumor grows slowly...
January 10, 2019: Internal Medicine
https://www.readbyqxmd.com/read/30626842/rectal-submucosal-tumor-mimicking-a-neuroendocrine-tumor
#7
Takahiro Utsumi, Atsushi Yamada, Takaki Sakurai, Shin'ichi Miyamoto
No abstract text is available yet for this article.
January 10, 2019: Internal Medicine
https://www.readbyqxmd.com/read/30626841/esophagectasis-related-to-rivastigmine
#8
Osamu Sasaki, Kazunori Sugimura, Masahiro Shinoda, Masaharu Shinkai
No abstract text is available yet for this article.
January 10, 2019: Internal Medicine
https://www.readbyqxmd.com/read/30626840/nivolumab-related-sclerosing-cholangitis-in-gastric-cancer
#9
Yoshiharu Motoo
No abstract text is available yet for this article.
January 10, 2019: Internal Medicine
https://www.readbyqxmd.com/read/30626839/decreased-mean-kurtosis-in-the-putamen-is-a-diagnostic-feature-of-minimal-hepatic-encephalopathy-in-patients-with-cirrhosis
#10
Takuro Sato, Kei Endo, Keisuke Kakisaka, Yuji Suzuki, Yohei Kooka, Kei Sawara, Kenji Ito, Makoto Sasaki, Yasuhiro Takikawa
Background & Aims To prevent the development of overt hepatic encephalopathy, the early intervention for minimal hepatic encephalopathy (MHE) based on an accurate diagnosis is essential. This study investigated whether or not magnetic resonance diffusion kurtosis imaging (DKI) and diffusion tensor imaging (DTI) could detect brain microstructure abnormalities in MHE. The aim was to confirm whether or not brain microstructure abnormalities detected by magnetic resonance (MR) imaging could be used for the diagnosis of MHE...
January 10, 2019: Internal Medicine
https://www.readbyqxmd.com/read/30626838/intracranial-hemorrhaging-following-cardiobacterium-hominis-endocarditis
#11
Eitaro Okumura, Junya Tsurukiri, Hiroshi Yamanaka, Yu Nakagawa, Kunitoshi Ootsuka, Yosuke Tanaka
Acute infectious endocarditis (IE) is a complex disease that presents as a serious clinical condition associated with a high mortality rate, especially due to intracranial hemorrhaging (ICH). The most common causative organism is Staphylococcus aureus. We herein report a patient with ICH following subacute IE with a positive blood culture for Cardiobacterium hominis. A review of the existing literature revealed that acute IE associated with Cardiobacterium has been reported to cause ICH in only seven previous cases...
January 10, 2019: Internal Medicine
https://www.readbyqxmd.com/read/30626837/development-of-propionibacterium-acnes-associated-sarcoidosis-during-etanercept-therapy-a-case-report
#12
Takuma Isshiki, Hisayo Matsuyama, Susumu Sakamoto, Naoko Honma, Tetuo Mikami, Kazutoshi Shibuya, Yoshinobu Eishi, Sakae Homma
Although numerous recent studies have reported the development of sarcoidosis in patients treated with TNF-α inhibitors, it is unclear whether the pathogenesis of drug-induced sarcoidosis is identical to that of spontaneous sarcoidosis. We herein present the case of a patient who developed sarcoidosis 6 months after the introduction of etanercept as treatment for rheumatoid arthritis. Typical clinical symptoms with noncaseating epithelioid granulomas detected in a mediastinal lymph node specimen were consistent with the diagnosis of sarcoidosis...
January 10, 2019: Internal Medicine
https://www.readbyqxmd.com/read/30626836/in-stent-massive-thrombi-formation-during-primary-percutaneous-coronary-intervention-in-a-patient-with-acute-myocardial-infarction-complicated-with-essential-thrombocythemia
#13
Keisuke Shoji, Kenji Yanishi, Jun Shiraishi, Naohiko Nakanishi, Kan Zen, Takeshi Nakamura, Masayuki Hyogo, Takeshi Shirayama, Satoaki Matoba, Takahisa Sawada
A 61-year-old man with essential thrombocythemia (ET) presented with acute myocardial infarction (AMI) and underwent primary percutaneous coronary intervention. After stent deployment from the left main (LM) to the left anterior descending artery, intravascular ultrasound revealed thrombi formation in the whole stent. Two days later, optical frequency domain imaging confirmed stent malapposition and thrombi remaining in only the LM. The stent malapposition and ET might have contributed to this phenomenon. He underwent an additional stent expansion and aggressive anti-thrombotic regimen...
January 10, 2019: Internal Medicine
https://www.readbyqxmd.com/read/30626835/hepatic-injury-without-granulomatous-formation-associated-with-intravesical-bacillus-calmette-gu%C3%A3-rin-therapy
#14
Hiroshi Okano, Hiroki Asakawa, Kenji Nose, Satomi Tsuruga, Tomomasa Tochio, Hiroaki Kumazawa, Yoshiaki Isono, Hiroshi Tanaka, Shimpei Matsusaki, Tomohiro Sase, Tomonori Saito, Katsumi Mukai, Akira Nishimura, Miki Usui, Youichirou Baba, Tetsuya Murata
A 74-year-old man developed hepatic injury after intravesical Bacillus Calmette-Guérin (BCG) therapy for bladder carcinoma. Although hepatitis-associated disseminated BCG was suspected, granulomatous formations were undetectable. The hepatic injury was considered to have resulted from an allergic reaction to BCG therapy because a histopathological assessment revealed enlarged portal areas with eosinophils and neutrophils. The hepatic injury was resolved by prednisolone. This case suggested that hepatic injury associated with BCG therapy might be due to an allergic mechanism unrelated to disseminated BCG disease...
January 10, 2019: Internal Medicine
https://www.readbyqxmd.com/read/30626834/an-adult-case-of-herpes-simplex-virus-associated-granulomatous-encephalitis
#15
Yuta Iwai, Kazutaka Nishimura, Takeshi Fukushima, Takashi Ito, Yoshiyuki Watanabe, Masahiro Noro, Satoshi Kuwabara
Brain granuloma occurs under certain conditions. Herpes simplex virus (HSV) causes granulomatous encephalitis in children; however, it has been rarely reported in adults. A 74-year-old man with a history of herpes simplex encephalitis suffered recurrent seizures. Brain magnetic resonance imaging revealed a mass lesion and resection was performed. A polymerase chain reaction using a brain biopsy specimen was positive for HSV DNA; thus, the patient was diagnosed with HSV-associated granulomatous encephalitis...
January 10, 2019: Internal Medicine
https://www.readbyqxmd.com/read/30626833/the-clinical-usefulness-of-the-pillcam-progress-indicator-for-route-selection-in-double-balloon-endoscopy
#16
Akiyoshi Tsuboi, Shiro Oka, Shinji Tanaka, Sumio Iio, Ichiro Otani, Sayoko Kunihara, Kazuaki Chayama
Objective The utility of capsule endoscopy (CE) findings in the route selection for double balloon endoscopy (DBE) has not been adequately discussed. The PillCam Progress Indicator in the RAPID 6.5 software program graphically demonstrates the progress of the capsule endoscope through the small bowel. This study aimed to clarify the usefulness of the PillCam Progress Indicator in choosing the initial DBE route. Methods We retrospectively examined 50 consecutive patients with 50 target lesions detected on both CE and DBE at Hiroshima University Hospital from January 2011 to February 2018...
January 10, 2019: Internal Medicine
https://www.readbyqxmd.com/read/30626832/clinical-and-genetic-aspects-of-beh%C3%A3-et-s-disease-in-japan
#17
Yohei Kirino, Hideaki Nakajima
Patients with Behçet's disease (BD) suffer from episodic ocular and mucocutaneous attacks, resulting in a reduced quality of life. The phenotype of Japanese BD has been changing over the past 20 years, and the rate of HLA-B*51-positive complete type is decreasing while that of intestinal type is increasing. This phenotypical evolution may be related to changes in as-yet-unknown environmental factors, as the immigration influx in Japan is low. Mechanisms discovered by genome-wide association studies include ERAP1-mediated HLA class I antigen bounding pathway, autoinflammation, Th17 cells, natural killer cells, and polarized macrophages, a similar genetic architecture to Crohn's disease, ankylosing spondylitis, and psoriasis...
January 10, 2019: Internal Medicine
https://www.readbyqxmd.com/read/30626831/hydroxychloroquine-improves-the-disease-activity-and-allows-the-reduction-of-the-corticosteroid-dose-regardless-of-background-treatment-in-japanese-patients-with-systemic-lupus-erythematosus
#18
Hironari Hanaoka, Harunobu Iida, Tomofumi Kiyokawa, Yukiko Takakuwa, Kimito Kawahata
Objective Hydroxychloroquine (HCQ) was not approved in Japan until 2015, and its therapeutic potential has not been explored in depth. We evaluated the additional therapeutic effect of HCQ in Japanese patients with systemic lupus erythematosus (SLE) on maintenance therapy. Methods Patients with SLE who visited our hospital from 2015 to 2016 and were taking prednisolone (PSL) at <20 mg/day were retrospectively evaluated. All patients were divided into three groups according to their maintenance treatment regimen: PSL + immunosuppressant, PSL alone, and no treatment...
January 10, 2019: Internal Medicine
https://www.readbyqxmd.com/read/30626830/successful-treatment-of-ros1-rearranged-lung-cancer-complicated-by-hypertrophic-pulmonary-osteoarthropathy-with-crizotinib-therapy-a-case-report
#19
Naoko Katsurada, Motoko Tachihara, Naoe Jimbo, Kiyoko Koyama, Kyosuke Nakata, Tatsuya Nagano, Masatsugu Yamamoto, Hiroshi Kamiryo, Kazuyuki Kobayashi, Yoshihiro Nishimura
Hypertrophic pulmonary osteoarthropathy (HPO) is a paraneoplastic syndrome characterized by digital clubbing, arthritis, and periostitis. Tumor removal usually leads to the resolution of these symptoms. We herein report the efficacy of crizotinib treatment for treating the symptoms of HPO associated with c-ros oncogene 1 receptor tyrosine kinase (ROS1)-rearranged lung cancer. A 71-year-old woman presented with a pulmonary tumor and arthritis. She was diagnosed with a ROS1-rearranged lung adenocarcinoma (stage IIIB [cT4N2M0]) with HPO...
January 10, 2019: Internal Medicine
https://www.readbyqxmd.com/read/30626829/efficacy-and-safety-of-chemotherapy-following-anti-pd-1-antibody-therapy-for-gastric-cancer-a-case-of-sclerosing-cholangitis
#20
Masashi Kono, Toshiharu Sakurai, Kazuki Okamoto, Shou Masaki, Tomoyuki Nagai, Yoriaki Komeda, Ken Kamata, Kosuke Minaga, Kentarou Yamao, Mamoru Takenaka, Tomohiro Watanabe, Naoshi Nishida, Masatoshi Kudo
Immunotherapy targeting programmed cell death-1 (PD-1) signaling is becoming the standard of care for advanced gastric cancer. We herein report a patient with gastric adenocarcinoma with peritoneal dissemination who was treated with nab-paclitaxel and ramucirumab following nivolumab and developed sclerosing cholangitis. Endoscopic retrograde cholangiography showed irregular narrowing and widening of the entire intrahepatic biliary system. Intriguingly, the patient receiving second-line chemotherapy with nab-paclitaxel plus ramucirumab prior to being administered nivolumab, however, he had experienced progressive disease...
January 10, 2019: Internal Medicine
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