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Internal Medicine

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https://www.readbyqxmd.com/read/29151542/ramucirumab-plus-paclitaxel-a-possible-new-chemotherapy-regimen-for-neuroendocrine-carcinoma-of-the-stomach
#1
Yoshiharu Motoo
No abstract text is available yet for this article.
November 20, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29151541/gastro-intestinal-involvement-in-m-3243a-g-associated-mitochondrial-myopathy-encephalopathy-lactic-acidosis-and-stroke-like-episodes
#2
Junichiro Suzuki, Mai Iwata, Hideyuki Moriyoshi, Suguru Nishida, Takeshi Yasuda, Yasuhiro Ito
No abstract text is available yet for this article.
November 20, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29151540/japanese-cardiovascular-disease-patients-with-diabetes-mellitus-suffer-increased-tooth-loss-in-comparison-to-those-without-diabetes-mellitus-a-cross-sectional-study
#3
Norio Aoyama, Jun-Ichi Suzuki, Naho Kobayashi, Tomoya Hanatani, Norihiko Ashigaki, Asuka Yoshida, Yuka Shiheido, Hiroki Sato, Hidetoshi Kumagai, Yuichi Ikeda, Hiroshi Akazawa, Issei Komuro, Masato Minabe, Yuichi Izumi, Mitsuaki Isobe
Objective Tooth loss is an irreversible condition that reflects the end-stage of oral diseases, including periodontitis. Although periodontitis is a major factor in the progression of diabetes mellitus (DM) and cardiovascular disease (CVD), no previous studies have compared tooth loss in CVD patients with and without DM. Methods The subjects included CVD patients with (n=94) and without (n=145) DM who attended Tokyo Medical and Dental University hospital. Blood examinations and periodontal measurements were performed...
November 20, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29151539/transient-collateral-arteries-developed-during-coronary-vasospasm
#4
Keitaro Akita, Sho Tanosaki, Keiichi Fukuda, Yuichiro Maekawa
No abstract text is available yet for this article.
November 20, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29151538/iron-deficiency-anemia-due-to-the-long-term-use-of-a-proton-pump-inhibitor
#5
Ryosuke Imai, Takakazu Higuchi, Masaya Morimoto, Ryosuke Koyamada, Sadamu Okada
A 52-year-old man who had been taking omeprazole, a proton pump inhibitor (PPI), for 25 years developed iron deficiency anemia. An evaluation of the entire gastrointestinal tract did not reveal any possible causes of gastrointestinal blood loss. The cause of the iron deficiency was considered to be a reduction in gastrointestinal iron absorption in association with the reduced secretion of gastric acid due to PPI use. This case demonstrates that long-term PPI use for as long as 25 years may cause iron deficiency anemia and should be considered in the differential diagnosis of iron deficiency anemia in long-term PPI users...
November 20, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29151537/ectopic-pancreatitis-of-the-jejunal-mesentery
#6
Kohei Yamakawa, Akira Kurita, Hiroaki Terajima, Shujiro Yazumi
No abstract text is available yet for this article.
November 20, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29151536/bilateral-hippocampal-infarction-mimicking-limbic-encephalitis
#7
Satoshi Hosoki, Hitoshi Satoi, Sadayuki Matsumoto
No abstract text is available yet for this article.
November 20, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29151535/multiple-endotracheal-metastases-of-lung-cancer-after-bronchoscopic-intervention-a-case-report
#8
Kazuki Hayasaka, Satoshi Shiono, Naoki Yanagawa
A 65-year-old man presented with obstructive pneumonia due to squamous cell carcinoma of the lung, which invaded the right main bronchus. Argon plasma coagulation was performed, which reduced his symptoms. Right pneumonectomy was performed after preoperative chemotherapy; the pathological diagnosis was T3N1M0 Stage IIIA. Fifteen months after surgery, he presented with bloody sputum. Bronchoscopy showed multiple endotracheal tumors, and a pathological examination revealed squamous cell carcinoma; the same histology as the primary lung cancer...
November 20, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29151534/a-case-of-colobronchial-fistula-causing-foul-smelling-sputum-with-a-fecal-odor
#9
Kazuhiro Kosugi, Tomohiro Nishi, Tatsuyuki Iijima, Tetsuya Tanimoto
No abstract text is available yet for this article.
November 20, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29151533/acute-urinary-retention-induced-by-chemical-meningitis-which-occurred-due-to-a-ruptured-dermoid-cyst
#10
Keiko Yamagami, Naoko Kakuta, Kaori Seki, Ryota Nakamura, Yusuke Hanioka, Tomoyuki Nakamura, Hitoshi Goto
Meningitis retention syndrome (MRS), a rare complication of aseptic meningitis, can present with acute urinary retention. The rupture of a dermoid cyst, which is a benign intracranial tumor, can sometimes induce chemical meningitis. We herein present a case of chemical meningitis and acute urinary retention that was induced by the rupture of a dermoid cyst. The patient experienced urinary retention for approximately 60 days, and then made a complete recovery thereafter. This is the first reported case of acute urinary retention due to the rupture of a dermoid cyst...
November 20, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29151532/association-of-admission-glucose-level-and-improvement-in-pulmonary-artery-pressure-in-patients-with-submassive-type-acute-pulmonary-embolism
#11
Masaomi Gohbara, Keigo Hayakawa, Azusa Hayakawa, Yusuke Akazawa, Yukihiro Yamaguchi, Shuta Furihata, Ai Kondo, Yusuke Fukushima, Sakie Tomari, Takayuki Mitsuhashi, Tsutomu Endo, Kazuo Kimura
Objective The admission glucose level is a predictor of mortality even in patients with acute pulmonary embolism (APE). However, whether or not the admission glucose level is associated with the severity of APE itself or the underlying disease of APE is unclear. Methods This study was a retrospective observational study. A pulmonary artery (PA) catheter was used to accurately evaluate the severity of APE. The percentage changes in the mean PA pressure (PAPm) upon placement and removal of the inferior vena cava filter (IVCF) were evaluated...
November 20, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29151531/repeated-hypoglycemic-episodes-with-postprandial-hyperinsulinemia-after-the-recovery-from-acute-weight-loss-revealed-by-continuous-glucose-monitoring-and-the-oral-glucose-tolerance-test
#12
Seizaburo Masuda, Masanori Murakami, Ryotaro Bouchi, Isao Minami, Koshi Hashimoto, Takanobu Yoshimoto, Yoshihiro Ogawa
We herein report a case of a 20-year-old woman who experienced hypoglycemia in parallel with acute weight loss confirmed by continuous glucose motoring (CGM). When she recovered from the acute weight loss, CGM revealed nocturnal and postprandial hypoglycemia. Six months were required to resolve the hypoglycemia and hyperinsulinemia after the recovery of her weight. Our case suggests that the adaption of insulin secretion to the rapid loss of weight and to the recovery of weight may require a long period of time, leading to the excessive secretion of insulin relative to the glucose level and repeated hypoglycemic episodes with postprandial hyperinsulinemia...
November 20, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29151530/successful-autologous-hematopoietic-stem-cell-transplantation-followed-by-bortezomib-maintenance-in-a-patient-with-relapsed-cd138-low-multiple-solitary-plasmacytomas-harboring-a-17p-deletion
#13
Hiroaki Kitamura, Yasushi Kubota, Kyosuke Yamaguchi, Kazuharu Kamachi, Atsujiro Nishioka, Masako Yokoo, Takero Shindo, Toshihiko Ando, Kensuke Kojima, Shinya Kimura
Solitary plasmacytoma of bone (SBP) tends to progress to multiple myeloma (MM); however, progression to multiple solitary plasmacytomas (MSP) is rare. We report a case of CD138-low MSP with 17p deletion in a patient with relapsed SBP. 17p deletion is associated with a poor outcome in patients with MM, and the low expression of CD138 in myeloma cells is associated with drug resistance and a poor prognosis. The patient was successfully treated with bortezomib plus dexamethasone induction therapy and autologous hematopoietic stem cell transplantation followed by bortezomib maintenance therapy...
November 20, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29151529/rare-case-of-pancreatic-cystic-lymphangioma
#14
Masakuni Fujii, Hiroaki Saito, Masao Yoshioka, Junji Shiode
Pancreatic cystic lymphangioma is an extremely rare tumor. The characteristic imaging findings are poorly defined, and distinguishing between this disease and other pancreatic cyst-related tumors is very difficult. We herein report a case of a Japanese woman in her 50s with this lesion, located in the tail of the pancreas. Pancreatic cystic lymphangioma should therefore be considered in the differential diagnosis of pancreatic cystic lesions. Laparoscopic resection can be a useful, minimally invasive surgical approach for treating these cysts as well as for the treatment of benign or low-grade malignant tumors located in the pancreatic body or tail...
November 20, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29151528/degeneration-of-the-substantia-nigra-following-ipsilateral-striatal-infarction
#15
Gaku Ohtomo, Tatsuo Mano, Akiko Seto, Shoji Tsuji
No abstract text is available yet for this article.
November 20, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29151527/gastrointestinal-involvement-in-m-3243a-g-associated-melas
#16
Josef Finsterer, Sinda Zarrouk-Mahjoub
No abstract text is available yet for this article.
November 20, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29151526/recent-inferior-myocardial-infarction-complicated-with-a-right-ventricular-thrombus-detected-by-three-cardiac-imaging-modalities
#17
Toshiki Kuno, Syohei Imaeda, Kenji Hashimoto, Toshinobu Ryuzaki, Tetsuya Saito, Hiroyuki Yamazaki, Ryota Tabei, Masaki Kodaira, Manabu Hase, Yohei Numasawa
We report the case of a 71-year-old woman diagnosed with recent inferior myocardial infarction complicated with right ventricular infarction and a right ventricular thrombus. Three-dimensional transthoracic echocardiography, contrast-enhanced computed tomography, and cardiac magnetic resonance imaging clearly detected a thrombus. We consider cases with a recent right ventricular infarction to require assessment for thrombus formations in the right ventricle. Fortunately, vigorous anticoagulation therapy resolved the thrombi in both the right ventricle and right coronary artery...
November 20, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29151525/achromobacter-infection-is-rare-in-japanese-patients-with-pulmonary-b-cell-lymphoma
#18
Satsuki Aoyama, Ayako Masaki, Yuma Sakamoto, Hisashi Takino, Takayuki Murase, Koichi Ohshima, Tadashi Yoshino, Seiichi Kato, Hiroshi Inagaki
Objective Achromobacter xylosoxidans (A. xylosoxidans) has been recently reported to have an association with the development of pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma in patients from European countries. However, the prevalence rates for A. xylosoxidans may vary significantly from country to country. To assess this association, the prevalence of A. xylosoxidans was analyzed in Japanese patients with pulmonary B-cell lymphoma. Methods DNA samples were obtained from formalin-fixed, paraffin-embedded sections of pulmonary MALT lymphomas (n=52), diffuse large B-cell lymphomas (DLBCLs, n=18), and benign pulmonary lesions (n=19)...
November 20, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29151524/atrioventricular-block-induced-torsades-de-pointes-associated-with-kcnq1-g269s
#19
Tadashi Nakajima, Takashi Sugawara, Yoshiaki Kaneko, Masahiko Kurabayashi
No abstract text is available yet for this article.
November 20, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29151523/neuroendocrine-carcinoma-of-the-stomach-a-response-to-combination-chemotherapy-consisting-of-ramucirumab-plus-paclitaxel
#20
Yuki Matsubara, Takayuki Ando, Ayumu Hosokawa, Hiroshi Mihara, Hiroaki Takagi, Naokatsu Nakata, Hiroki Yoshita, Sohachi Nanjo, Shinya Kajiura, Haruka Fujinami, Toshiro Sugiyama
Extrapulmonary neuroendocrine carcinoma (NEC) is a rare disease, and there is no standard chemotherapy. A 73-year-old man was diagnosed with advanced gastric NEC. He received chemotherapy of irinotecan plus cisplatin, and amrubicin monotherapy. After failure of second-line chemotherapy, he received ramucirumab plus paclitaxel; this treatment was chosen because vascular endothelial growth factor 2 was strongly expressed in the tumor endothelial cells. After two cycles, his NEC had markedly reduced in size, and he continued with this treatment for over eight months...
November 20, 2017: Internal Medicine
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