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ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs

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https://www.readbyqxmd.com/read/30418191/calcium-priming-of-the-central-venous-catheter-prevents-a-drop-in-ionized-calcium-concentration-during-regional-citrate-anticoagulation
#1
Giulia Roveri, Mattia Busana, Andrea Clarissa Lusardi, Federica Ferrari, Giacomo Trevisan, Luca Di Girolamo, Marco Dei Poli, Marco Vittorio Resta
During citrate-based Continuous Renal Replacement Therapy (CRRT), an infusion of calcium is necessary to replace the calcium lost in the effluent. The replacement takes place through a central venous catheter (CVC) that is primed with saline solution. Thus, we hypothesized a potential systemic anticoagulation because of unchelated citrate reaching the patient at the start of CRRT because of 0.42 ml of line dead space. In this pilot study, two subpopulations of 7 patients who underwent Continuous Veno-Venous Hemodiafiltration (150 ml/min of blood flow, 1500 ml/h dialysate, 1500 ml/h of citrate predilution) were studied...
November 7, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/30418190/extracorporeal-technologies-within-the-social-media-labyrinth
#2
Justyna Swol
No abstract text is available yet for this article.
November 7, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/30398982/obesity-is-associated-with-driveline-infection-of-left-ventricular-assist-devices
#3
Mehmet H Akay, Sriram S Nathan, Rajko Radovancevic, Gregor Poglajen, Mateja K Jezovnik, Isabella N Candelaria, Barbara L Averill, Manish K Patel, Biswajit Kar, Igor D Gregoric
In patients with left ventricular assist devices (LVADs), the association of driveline infection (DLI) and body mass index (BMI) remains controversial. The aim of this study was to explore a potential correlation between BMI and DLI in the LVAD patient population. A retrospective, single-center study evaluated patients who underwent LVAD implantation between May 2012 and July 2016. Driveline infection was evaluated per Interagency Registry for Mechanically Assisted Circulatory Support established criteria. Of 222 included patients, 80% were male, the average age was 55 years, and the main underlying heart failure diagnosis was nonischemic cardiomyopathy (56%)...
November 5, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/30398981/large-dual-lumen-extracorporeal-membrane-oxygenation-cannulas-are-associated-with-more-intracranial-hemorrhage
#4
Michael Mazzeffi, Zachary Kon, Jay Menaker, Daniel M Johnson, Orlando Parise, Sandro Gelsomino, Roberto Lorusso, Daniel Herr
Large dual-lumen veno-venous (VV) extracorporeal membrane oxygenation (ECMO) cannulas may increase venous pressure in the brain, contributing to intracranial hemorrhage (ICH). A retrospective cohort study was performed using the extracorporeal life support organization (ELSO) registry. Propensity score matching was used to control for confounding. The rate of ICH and rates of hemolysis, cannula complications, and mortality were compared between patients with a 27 French dual-lumen cannula and patients with a 31 French dual-lumen cannula...
November 5, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/30394887/usefulness-of-glycemic-control-using-an-artificial-pancreas-apparatus-for-cardiovascular-surgery
#5
Hisashi Uemura, Naosumi Sekiya, Masataka Mitsuno, Mitsuhiro Yamamura, Hiroe Tanaka, Masaaki Ryomoto, Ayaka Sato, Daisuke Ueda, Yuji Miyamoto
Blood glucose management is important for cardiovascular surgery using cardiopulmonary bypass. The usefulness of an artificial pancreas apparatus (STG-55) to control blood glucose in patients undergoing cardiopulmonary bypass was investigated. Subjects comprised 44 patients using the artificial pancreas during cardiopulmonary bypass between June 2016 and March 2017; 55 were initially enrolled, but 11 were excluded because of blood removal failure. Patients were divided into a monitoring group in which blood glucose levels were only monitored using the artificial pancreas (11 patients: six people with diabetes and 5 people without diabetes) and a management group with glycemic control by automatic insulin administration using the artificial pancreas (33 patients: people with diabetes and 21 people without diabetes)...
October 31, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/30394886/surgical-techniques-for-implanting-the-evaheart-2-double-cuff-tipless-inflow-cannula
#6
Tadashi Motomura, Brian Kelly
The EVAHEART 2 (Sun Medical Technology Research Corporation, Nagano, Japan) is an investigational centrifugal ventricular assist device in the United States, introduced a new type inflow, named "double cuff tipless" inflow cannula intended to mitigate the risks of cannula malposition and subsequent ischemic stroke events associated with thrombi around the inflow cannula. To achieve these performance benefits of the "tipless" design, however, it is crucial to adhere to the recommended surgical procedure...
October 31, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/30394885/lung-biopsy-in-patients-with-acute-respiratory-distress-syndrome-supported-on-extracorporeal-membrane-oxygenation-a-2-year-experience
#7
Kirsten M Lipps, Ankit Bharat, James M Walter
No abstract text is available yet for this article.
October 31, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/30334827/left-ventricular-ejection-fraction-depends-on-loading-conditions
#8
Philippe Morimont, Bernard Lambermont
No abstract text is available yet for this article.
October 16, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/30325848/suitability-of-3d-printed-root-models-for-the-development-of-transcatheter-aortic-root-repair-technologies
#9
Enrico Ferrari, Giulia Piazza, Martin Scoglio, Denis Berdajs, Piergiorgio Tozzi, Francesco Maisano, Ludwig Karl Von Segesser
Transcatheter aortic root repair (TARR) is still not available because of the complex anatomy. In order to develop future TARR technologies, a human-derived bench test model is required before performing animal tests. For this purpose, we aimed to validate computed tomography (CT)-derived 3D-printed root models for TARR technologies. Four human CT-derived roots were printed using different resins: Visijet M3 Crystal, Photopolymer gel SUP705, Formlabs flexible resin, and Materialise HeartPrint Flex. A stress test was performed using a 26-mm balloon-expandable Sapien valve deployed in aortic position...
October 10, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/30325847/preoperative-predictors-of-mortality-in-short-term-continuous-flow-ventricular-assist-devices
#10
Sabin J Bozso, Holger Buchholz, Tara Pidborochynski, Darren H Freed, Roderick G MacArthur, Jennifer Conway
Short-term continuous-flow ventricular assist devices (STCF-VADs) are increasingly being utilized to support critically ill patients, despite limited information regarding overall outcomes. All adult patients supported with an STCF-VAD between June 2009 and December 2015 were included in this retrospective single-center study. Associations between preoperative characteristics and unsuccessful bridge (death on device or within 30 days postdecannulation) were assessed using logistic regression. A total of 61 patients (77% male) were identified with a median age at implant of 54...
October 10, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/30325846/extracorporeal-membrane-oxygenation-for-adults-with-refractory-septic-shock
#11
Jordi Riera, Eduard Argudo, Juan Carlos Ruiz-Rodríguez, Ricard Ferrer
Because of a severe dysregulation of the host response to infection, septic shock may induce a profound imbalance between oxygen consumption and delivery, which in some cases may be refractory to conventional support measures. In this setting, extracorporeal membrane oxygenation (ECMO) may help to restore this ratio. Indeed, in neonates and children, this technique is already established as a valid salvage therapy. In spite of the rapid growth in the use of ECMO in recent years, the evidence of its benefits in adult patients is weak, particularly in cases of refractory septic shock...
October 10, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/30312213/left-ventricular-assist-devices-how-do-we-define-success
#12
Lucman A Anwer, Salvatore Poddi, Vakhtang Tchantchaleishvili, Richard C Daly, Hadi Toeg, Jacob J Strand, John M Stulak, Simon Maltais
Despite the growing acceptance of left ventricular assist device (LVAD) therapy to improve survival and quality of life in heart failure (HF) patients, uncertainties persist regarding the definition of a successful implant. We sought to define an innovative approach to assess success and subsequently compare preoperative variables affecting outcomes. From January 2007 to 2015, 278 patients underwent LVAD implantation. Median age at implant was 62 years and 81% patients were males. Indication for support was bridge-to-transplantation in 36% patients and the etiology of HF was ischemic in 49% patients...
October 9, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/30312212/impact-of-diabetes-mellitus-on-survival-in-patients-bridged-to-transplantation-with-left-ventricular-assist-devices-in-the-united-states
#13
Sadeer G Al-Kindi, Jassim Al-Suwaidi, Amin Jayyousi, Guilherme H Oliveira, Charbel Abi Khalil
Diabetes mellitus (DM) is associated with increased mortality in advanced heart failure and in patients undergoing cardiac surgery. However, its impact on outcomes in patients supported with left ventricular assist devices (LVAD) is not well established. We queried the United Network for Organ Sharing (UNOS) for all adults listed for heart transplantation and bridged with continuous-flow LVAD in the United States from 2000 to 2015. We compared the pre- and post-transplant mortality of patients with and without DM...
October 9, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/30312211/the-impact-of-infection-and-elevated-inr-in-lvad-associated-intracranial-hemorrhage-a-case-crossover-study
#14
Sung-Min Cho, Tiffany Lee, Randall C Starling, Nicolas R Thompson, Ken Uchino
Despite the common occurrence left ventricular assist device (LVAD)-associated intracranial hemorrhage, the etiology of intracranial hemorrhage is uncertain. We aim to explore the impact of infection and international normalized ratio (INR) on intracranial hemorrhage in a case-crossover study. We reviewed consecutive patients with intracranial hemorrhage in a prospectively collected data of LVAD patients from a single, tertiary center from October 2004 to December 2016. Information on infection and INR values were collected at the time and 1 month before the intracranial hemorrhage as controls...
October 9, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/30312210/intravenous-versus-oral-iron-replacement-in-patients-with-a-continuous-flow-left-ventricular-assist-device
#15
Lauren E Bode, Sharon Wesner, Jason N Katz, Christopher V Chien, Ian Hollis
No abstract text is available yet for this article.
October 9, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/30312209/the-physiologic-basis-of-ejection-fraction
#16
Hoong Sern Lim
No abstract text is available yet for this article.
October 9, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/30312208/predictors-of-survival-for-patients-with-acute-decompensated-heart-failure-requiring-extra-corporeal-membrane-oxygenation-therapy
#17
A Reshad Garan, Waqas A Malick, Marlena Habal, Veli K Topkara, Justin Fried, Amirali Masoumi, Aws K Hasan, Dimitri Karmpaliotis, Ajay Kirtane, Melana Yuzefpolskaya, Maryjane Farr, Yoshifumi Naka, Dan Burkhoff, Paolo C Colombo, Paul Kurlansky, Hiroo Takayama, Koji Takeda
Chronic systolic heart failure (HF) with acute decompensation can result in cardiogenic shock (CS) requiring short-term mechanical circulatory support. We sought to identify predictors of survival for acute decompensated HF (ADHF) patients requiring veno-arterial extracorporeal membrane oxygenation (VA-ECMO). Patients >18 years old treated at our institution with VA-ECMO from 2009 to 2018 for ADHF with CS were studied. Demographic, hemodynamic, and echocardiographic data were collected. The primary outcome was survival to discharge...
October 9, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/30312207/yellow-means-caution-correlations-between-liver-injury-and-mortality-with-the-use-of-va-ecmo
#18
Luke Masha, Shareez Peerbhai, David Boone, Fisayomi Shobayo, Aman Ghotra, Bindu Akkanti, Yelin Zhao, Igor Banjac, Igor D Gregoric, Biswajit Kar
Abnormalities in markers of liver injury after venoarterial extracorporeal membrane oxygenation (VA-ECMO) initiation are of unclear distribution and clinical significance. This study included all consecutive adult patients from a single institution who underwent VA-ECMO cannulation between May 2012 and September 2016 and had liver function panels drawn during their admission (n = 223). Data points include: age, sex, body mass index, diagnosis, duration of ECMO cannulation, duration of hospitalization, pre-ECMO cardiac arrest, central nervous system (CNS) injury, the presence of chronic kidney disease or acute renal failure, renal replacement therapy utilization, lactate levels, duration of pre-ECMO intubation, admission and peak bilirubin/aspartate aminotransferase (AST)/alanine aminotransferase (ALT)/alkaline phosphatase (ALP) levels, and time to peak bilirubin/AST/ALT/ALP in relation to cannulation...
October 9, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/30325849/hemoadsorption-does-not-affect-hemolysis-during-cardiopulmonary-bypass
#19
Martin H Bernardi, Harald Rinoesl, Robin Ristl, Ulrike Weber, Dominik Wiedemann, Michael J Hiesmayr
Cardiopulmonary bypass (CPB) induces hemolysis, which manifests as plasma free hemoglobin. We investigated in a post hoc analysis of a single-center, blinded, controlled study whether the use of a novel hemoadsorption device (CytoSorb, CytoSorbents Europe GmbH, Berlin, Germany) affects hemolysis during CPB. A total of 35 patients undergoing elective CPB surgery with an expected CPB duration of more than 120 min were included in the analysis. The hemoadsorption device was used in 17 patients (intervention group) and not used in 18 patients (control group)...
October 8, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/30299303/chronic-in-vivo-test-of-a-right-heart-replacement-blood-pump-for-failed-fontan-circulation
#20
Joshua Cysyk, Joseph Brian Clark, Ray Newswanger, Choon-Sik Jhun, Jenelle Izer, Heidi Finicle, John Reibson, Bradley Doxtater, William Weiss, Gerson Rosenberg
An implantable rotary blood pump was developed to provide long-term mechanical right heart support for patients who have failing Fontan circulation. The objective of this study was to evaluate the pump in vivo in a 30 day sheep study. Pump speed was set at 3,900 rpm for the duration of the study, and pump power was between 4.3 and 4.6 W. The pump inlet pressures for the superior vena cava (SVC) and inferior vena cava (IVC) were 14 ± 15 and 11 ± 15 mm Hg, respectively, over the duration of the study. Hematocrit remained stable at 30% ± 4%...
October 3, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
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