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Dermatology: International Journal for Clinical and Investigative Dermatology

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https://www.readbyqxmd.com/read/30408786/depression-symptoms-predict-worse-clinical-response-to-etanercept-treatment-in-psoriasis-patients
#1
Waishu Jin, Shuqing Zhang, Yanjuan Duan
BACKGROUND/AIMS: This study aimed to investigate the predicting values of depression and anxiety symptoms for clinical response to etanercept treatment in psoriasis patients. METHODS: A total of 85 psoriasis patients who received 6 months of etanercept treatment were consecutively enrolled in this prospective cohort study. The Psoriasis Area and Severity Index (PASI) score was evaluated at month 0 (M0), M1, M3, and M6, and the corresponding PASI 75/90 response at each visit was assessed...
November 8, 2018: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/30404090/body-piercing-a-national-survey-in-france
#2
Nicolas Kluger, Laurent Misery, Sophie Seité, Charles Taieb
BACKGROUND: There are no recent data available in France regarding body piercing (BP). OBJECTIVE: We examined the demographics, motivations, quality of life, cutaneous conditions, and cutaneous side effects after BP within the French population. METHODS: A representative sample of 5,000 individuals (aged 15 and over) from the general population responded to a survey online between April and August 2017. Data regarding demographics, BP characteristics (location, age at first piercing, hesitation, regrets, motivations, cutaneous side effects), tobacco, skin conditions (acne, contact eczema, atopic eczema, rosacea, psoriasis, vitiligo), and tattoos were collected...
November 7, 2018: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/30404085/redesigning-skin-cancer-early-detection-and-care-using-a-new-mobile-health-application-protocol-of-the-skin-research-project-a-randomised-controlled-trial
#3
Monika Janda, Caitlin Horsham, Uyen Koh, Nicole Gillespie, Lois J Loescher, Dimitrios Vagenas, H Peter Soyer
Patients often detect melanoma themselves; therefore, regular skin self-examinations (SSEs) play an important role in the early detection and prompt treatment of melanoma. Mobile teledermoscopy is a technology that may facilitate consumer SSEs and rapid communication with a dermatologist. This paper describes the planned randomised controlled trial of an intervention to determine whether mobile technologies can help improve the precision of SSE in consumers. A randomised controlled trial will be conducted to evaluate mobile teledermoscopy-enhanced SSE versus naked-eye SSE...
November 7, 2018: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/30404081/consumer-acceptance-and-expectations-of-a-mobile-health-application-to-photograph-skin-lesions-for-early-detection-of-melanoma
#4
Uyen Koh, Caitlin Horsham, H Peter Soyer, Lois J Loescher, Nicole Gillespie, Dimitrios Vagenas, Monika Janda
BACKGROUND: Mobile teledermoscopy may facilitate skin self-examinations (SSEs) and further improve monitoring and detection of melanoma. OBJECTIVE: To assess consumer acceptability and expectations of a mobile health app used to: (i) instruct SSE and (ii) conduct consumer-performed mobile teledermoscopy. METHODS: People aged 18 years and above were invited to participate in either (i) an online survey or (ii) focus group in Brisbane, Australia...
November 7, 2018: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/30404078/lesions-mimicking-melanoma-at-dermoscopy-confirmed-basal-cell-carcinoma-evaluation-with-reflectance-confocal-microscopy
#5
Francesca Peccerillo, Victor Desmond Mandel, Francesca Di Tullio, Silvana Ciardo, Johanna Chester, Shaniko Kaleci, Nathalie de Carvalho, Ester Del Duca, Luca Giannetti, Laura Mazzoni, Steven Paul Nisticò, Ignazio Stanganelli, Giovanni Pellacani, Francesca Farnetani
BACKGROUND: Atypical basal cell carcinoma (BCC), characterized by equivocal dermoscopic features typical of malignant melanoma (MM), can be difficult to diagnose. Reflectance confocal microscopy (RCM) enables in vivo imaging at nearly histological resolution. OBJECTIVES: To evaluate with RCM atypical melanocytic lesions identified in dermoscopy, according to common RCM criteria for the differential diagnosis of BCC, and to identify representative RCM parameters for superficial (sBCCs) and nonsuperficial (nsBCCs) basal cell carcinomas (BCCs)...
November 7, 2018: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/30380550/the-influence-of-breast-cancer-on-the-distribution-of-cherry-angiomas-on-the-anterior-thoracic-wall-a-case-series-study
#6
Antonio Guastafierro, Vincenzo Verdura, Bruno Di Pace, Mario Faenza, Corrado Rubino
BACKGROUND/AIMS: Cherry angiomas (CAs) are one of the most common vascular manifestations of the skin. By and large, these benign lesions often only represent an aesthetic problem. In the literature, few authors have focused on the pathogenesis of these lesions, and some risk factors have been identified, such as the presence of cutaneous and non-skin neoplasias. In this study, the correlation between the distribution of CAs and breast cancer was investigated. METHODS: We carried out a study whereby 50 women with unilateral breast cancer and the presence of CAs on the anterior thoracic wall were evaluated, with a particular focus on the difference in the number of CAs between the two haemithoraces...
October 31, 2018: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/30368496/standardized-photographic-documentation-of-hidradenitis-suppurativa-acne-inversa
#7
Christos C Zouboulis, André Nogueira da Costa
BACKGROUND: Despite existing guidelines and methods for standardized clinical photography in dermatology and plastic surgery, human skin exhibits exquisite site-specific morphologies and functions, and each body region can exhibit an individual pathologic phenotype. The aim of this work was to develop a standardized, representative and reproducible documentation of the multilocular hidradenitis suppurativa/acne inversa (HS) lesions, a disease mostly occurring in skin folds. METHOD: Optimal body positions for medical photography of candidate areas for HS involvement were evaluated...
October 26, 2018: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/30368494/adolescent-onset-hidradenitis-suppurativa-prevalence-risk-factors-and-disease-features
#8
Alejandro Molina-Leyva, Carlos Cuenca-Barrales
BACKGROUND/AIMS: Hidradenitis suppurativa (HS) is a chronic inflammatory and destructive skin disorder. Early diagnosis and treatment are critical to stop its progression. Data concerning adolescent-onset HS are scarce. The aims of this study are to describe the prevalence of adolescent-onset HS and to explore potential risk factors and the disease features of these patients. PATIENTS AND METHODS: A cross-sectional study including 134 patients was performed. RESULTS: Adolescent-onset HS occurred in 51...
October 26, 2018: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/30332667/tattoos-among-professional-atp-and-wta-tennis-players
#9
LETTER
Nicolas Kluger
No abstract text is available yet for this article.
October 17, 2018: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/30332666/defining-the-molecular-genetics-of-dermoscopic-naevus-patterns
#10
REVIEW
Jean-Marie Tan, Lisa N Tom, H Peter Soyer, Mitchell S Stark
Melanocytic naevi are common melanocytic proliferations that may simulate the appearance of cutaneous melanoma. Naevi commonly harbour somatic mutations implicated in melanomagenesis but in most cases lack the necessary genomic alterations required for melanoma development. While the mitogen-activated protein kinase pathway and ultraviolet radiation strongly contribute to naevogenesis, the somatic mutational landscape of dermoscopic naevus subsets distinguishes some of the molecular hallmarks of naevi in relation to melanoma...
October 17, 2018: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/30278434/micropapular-cutaneous-sarcoidosis-reviewed
#11
REVIEW
Jessica G Labadie, Aleksandra G Florek, Timothy VandenBoom, Pedram Yazdan, Aleksandar L Krunic
BACKGROUND: Micropapular cutaneous sarcoidosis (MPCS) is a rare variant of sarcoidosis. Herein we review the literature and include a recent case of MPCS discussing pathogenesis, diagnosis, treatment, and prognosis. METHOD: A review was conducted using the terms "micropapular sarcoidosis" and "micropapular sarcoid." A recent case of a 50-year-old male patient with biopsy-identified MPCS was also included in the review. RESULTS: In total, 12 cases with an aggregate of 18 patients were included in the review...
October 2, 2018: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/30269141/retrospective-analysis-of-91-kaposi-s-sarcoma-cases-a-single-center-experience-and-review-of-the-literature
#12
Serkan Yazici, Ozge Zorlu, Emel Bulbul Baskan, Saduman Balaban Adim, Kenan Aydogan, Hayriye Saricaoglu
BACKGROUND: Kaposi's sarcoma (KS) is a multifocal angioproliferative tumor involving primarily the skin. OBJECTIVE: The aim of this study was to describe the clinical, demographic, histopathological characteristics, treatment modalities, and outcome of 91 KS patients, and compare them with other contemporary research. METHODS: Medical records of 91 KS patients followed between January 2005 and September 2017 were evaluated retrospectively...
September 28, 2018: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/30253394/using-advances-in-skin-imaging-technology-and-genomics-for-the-early-detection-and-prevention-of-melanoma
#13
EDITORIAL
Monika Janda, H Peter Soyer
No abstract text is available yet for this article.
September 25, 2018: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/30227428/impaired-skin-barrier-function-and-downregulated-expression-of-caspase-14-in-moderate-to-severe-chronic-hand-eczema
#14
Ben Wang, Ling-Ling Liu, Zuo-Tao Zhao, Ping Tu
AIM: To investigate whether the skin barrier function is impaired with regard to the pH value, water content, transepidermal water loss (TEWL), and the integrity of the stratum corneum, and whether the expression of caspase-14 is altered in moderate to severe chronic hand eczema (CHE). METHODS: Thirty patients with moderate to severe CHE treated at our institute and 30 healthy volunteers were included in this study. The pH value, water content, TEWL, and the integrity of the stratum corneum were measured in all subjects...
September 18, 2018: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/30205412/epidemiological-and-clinical-patterns-of-kaposi-sarcoma-a-16-year-retrospective-cross-sectional-study-from-yaound%C3%A3-cameroon
#15
Dahlia Noëlle Tounouga, Emmanuel Armand Kouotou, Jobert Richie Nansseu, Anne-Cécile Zoung-Kanyi Bissek
BACKGROUND: The burden of Kaposi sarcoma (KS) is increasing fast among HIV-infected populations, but the disease remains desperately underexplored in Cameroon, where the burden of HIV is high. METHODS: This is a retrospective cross-sectional study carried out over a period of 16 years (January 2001 to December 2016) at the HIV day care unit of the Central Hospital of Yaoundé, Cameroon. The diagnosis was based on clinical aspects and histological confirmation, and we used a preconstructed questionnaire for data collection through patients' electronic and physical files...
September 11, 2018: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/30205372/prevalence-of-phototherapy-in-the-age-of-biologics
#16
Piergiacomo Calzavara-Pinton, Arianna Zanca, Mariachiara Arisi, Maria Teresa Rossi, Cristina Zane, Marina Venturini, Bernhard Ortel
BACKGROUND: The prevalence of narrow-band ultraviolet B (NB-UVB) use in Europe for moderate and severe psoriasis is unknown, because national registries for psoriasis do not monitor this treatment. OBJECTIVES: To quantify the use of phototherapy, biologics or conventional treatments in psoriasis, in a setting where European Medicines Agency (EMA) eligibility criteria for biologics were strictly applied, and phototherapy was included among first-line treatments. METHODS: We followed a cohort of 1,090 patients who were referred to the only centre entitled to prescribe biologics and phototherapy during a 5-year period...
September 11, 2018: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/30199884/polymorphous-light-eruption-phototherapy-based-desensitization-versus-intramuscular-steroids-who-is-right-who-is-wrong
#17
Florence Libon, Arjen F Nikkels
No abstract text is available yet for this article.
September 10, 2018: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/30199871/cutaneous-arteriolosclerosis-is-not-specific-to-ischemic-hypertensive-leg-ulcers
#18
Jean-Benoît Monfort, Karine Cury, Philippe Moguelet, François Chasset, Claude Bachmeyer, Camille Francès, Annick Barbaud, Patricia Senet
BACKGROUND: The histological characteristic of hypertensive leg ulcers (HLU) is the presence of "arteriolosclerosis." The pertinence of performing a skin biopsy to diagnose HLU is questionable, as cutaneous arteriolosclerosis may be related to patient comorbidities. The objective here was to evaluate the frequency of arteriolosclerosis in skin leg biopsies performed in patients without ulcer and in control patients with HLU. METHODS: We performed a retrospective study between January 2013 and July 2014...
September 10, 2018: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/30176661/decreased-systemic-levels-of-endocan-1-and-cxcl16-in-psoriasis-are-restored-following-narrowband-uvb-treatment
#19
Gunnthorunn Sigurdardottir, Anna-Karin Ekman, Deepti Verma, Charlotta Enerbäck
BACKGROUND: In psoriasis, a common immune-mediated disease affecting 2-3% of the population worldwide, there is an increased prevalence of extracutaneous diseases including obesity, the metabolic syndrome, and cardiovascular disease. This is believed to be linked to systemic inflammation. In previous studies, we have explored various markers in plasma and serum to characterize the ongoing systemic inflammation in psoriasis patients compared to controls. We have identified several markers that were altered in psoriasis patients, but which all were unresponsive to narrowband UVB (NB-UVB) treatment...
September 3, 2018: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/30176655/tattoos-and-penalty-success-at-the-fifa-world-cup-2018
#20
LETTER
Simon M Müller, Samuel Hogg, Peter Itin
No abstract text is available yet for this article.
September 3, 2018: Dermatology: International Journal for Clinical and Investigative Dermatology
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