journal
MENU ▼
Read by QxMD icon Read
search

Dermatology: International Journal for Clinical and Investigative Dermatology

journal
https://www.readbyqxmd.com/read/29339636/successful-treatment-of-autoimmune-urticaria-with-low-dose-prednisolone-therapy-administered-for-a-few-months-a-case-series-of-42-patients
#1
Krisztina Vas, Anita Altmayer, Lilla Mihályi, Edina Garaczi, Ágnes Kinyó, Eszter Jakobicz, Sándor Husz, Lajos Kemény, Zsuzsanna Bata-Csörgő
BACKGROUND: Chronic spontaneous urticaria (CSU) is defined as symptoms of urticaria persisting for 6 weeks or more without obvious cause. Autologous serum skin test (ASST) positivity in patients with CSU is considered to be associated with autoimmune urticaria (AIU). METHODS: In this retrospective study we retrieved the medical records of 1,073 urticaria patients seen at the Department of Dermatology and Allergology of Szeged University between January 2005 and February 2014...
January 17, 2018: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/29320765/emerging-treatment-options-in-atopic-dermatitis-systemic-therapies
#2
Uffe Nygaard, Christian Vestergaard, Mette Deleuran
The pathogenesis of atopic dermatitis (AD) is multifactorial and intricate, and the clinical presentation of the condition varies greatly. Symptoms and severity depend on individual trigger factors and stage of the disease. The majority of AD patients are sufficiently treated with emollients in combination with existing topical or systemic therapies. Yet treatment failure with existing drugs and treatment options can be a significant clinical problem. New treatments are under development, and the majority of these new drugs focus on targeting a skewed immune response in AD...
January 11, 2018: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/29316554/skin-infections-due-to-bacteria-in-solid-organ-transplant-recipients-a-review
#3
Muneeb Ilyas, Nishita Maganty, Zachary Ginsberg, Amit Sharma
Though there is an abundance of information on cutaneous malignancies in transplant recipients, cutaneous infections in solid organ transplant recipients (SOTRs) are underrepresented in the dermatological literature. Our paper provides a comprehensive review of bacterial cutaneous infections within the solid organ transplant population. Cutaneous bacterial infections may lead to significant morbidity and even mortality in this immunosuppressed population. Thus, it is to the benefit of both dermatologists and other transplant care providers to better understand and recognize the features of cutaneous bacterial infections in SOTRs...
January 10, 2018: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/29258098/the-magnitude-of-mtorc1-signalling-may-predict-the-response-to-isotretinoin-treatment-in-patients-with-hidradenitis-suppurativa
#4
Valerio De Vita, Bodo C Melnik
No abstract text is available yet for this article.
December 20, 2017: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/29258093/th17-inhibitors-in-active-psoriatic-arthritis-a-systematic-review-and-meta-analysis-of-randomized-controlled-clinical-trials
#5
Girish S Naik, Wai K Ming, Itai M Magodoro, Babatunde Akinwunmi, Sara Dar, Henrik E Poulsen, Lars E Kristensen, Christina Ellervik
BACKGROUND: Several biologics targeting the Th17 pathway have been developed for the treatment of psoriatic arthritis (PsA), a disabling disease with moderate response and an increased incidence of serious infections to first-line biologics (TNF-α antagonists). Th17 inhibitors could replace TNF-α antagonists as first-line biologic agents. We determined the overall treatment effect of Th17 pathway inhibitors compared to placebo or active control on American College of Rheumatology (ACR) 20 response at week 12 (primary objective), risk of infections, discontinuation of treatment due to adverse events, and serious adverse events during the placebo-controlled period (12-24 weeks) in adults with active PsA in published randomized controlled trials...
December 20, 2017: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/29241216/melanoma-screening
#6
Karsten Juhl Jørgensen
No abstract text is available yet for this article.
December 15, 2017: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/29237168/evaluation-of-the-national-swiss-skin-cancer-screening-campaign-2013-do-we-do-the-right-thing
#7
Ralph-Peter Braun, Karina Ulrich, Robert Hunger, Olivier Gaide, Andreas Arnold, Rastine Merat, Reinhard Dummer, Jürg Hafner, Lars E French, Antonio Cozzio
BACKGROUND: Skin cancer prevention and screening programs are performed in many countries. Their benefit is discussed controversially. OBJECTIVE: Our aim is to evaluate the Skin Cancer Screening Program 2013 in Switzerland by following up screenees upon interventions. METHODS: Quality was assessed by personal follow-up via phone/e-mail of every patient that had been screened during this campaign and histological follow-up of all participants with suspicious skin lesions...
December 14, 2017: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/29237158/dermoscopy-of-morphea-and-cutaneous-lichen-sclerosus-clinicopathological-correlation-study-and-comparative-analysis
#8
Enzo Errichetti, Aimilios Lallas, Zoe Apalla, Alessandro Di Stefani, Giuseppe Stinco
BACKGROUND: Dermoscopy of morphea and cutaneous lichen sclerosus (CLS) has been described by various studies, with none of them considering variability according to clinical phases and investigating dermoscopic-histological correlations. OBJECTIVE: To evaluate dermoscopic features in general and according to clinical stage, identify possible distinctive dermoscopic clues, and assess dermoscopy accuracy in detecting subclinical alterations in morphea and CLS. METHODS: A representative dermoscopic image of target lesions was evaluated for the presence of specific features, correlating them with clinical subtype (inflammatory, inflammatory-sclerotic, sclerotic, or sclerotic-atrophic)...
December 14, 2017: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/29232687/photochemotherapy-and-graft-versus-leukemia-reaction-in-acute-leukemia-tumor-immunity-and-survival-are-dependent-on-timing-of-photochemotherapy-of-the-skin
#9
Nicolas Feldreich, Olle Ringden, Lennart Emtestam
BACKGROUND: Cure of acute leukemia after transplantation is mediated by the grafted cells. We investigated the graft-versus-leukemia effect (GVL) in patients with cutaneous acute graft-versus-host disease (GVHD) treated with photochemotherapy (psoralen and ultraviolet light type A). METHOD: Forty-seven patients with acute leukemia were followed 5,000 days after transplantation to assess survival and GVL by multivariate analysis. The primary predictor was time to treatment of cutaneous acute GVHD by photochemotherapy separated into treatment start during the first week of acute GVHD versus after the first week of acute GVHD...
December 13, 2017: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/29232663/serum-leptin-resistin-and-adiponectin-concentrations-in-psoriasis-a-meta-analysis-of-observational-studies
#10
Aikaterini Kyriakou, Aikaterini Patsatsi, Dimitrios Sotiriadis, Dimitrios G Goulis
BACKGROUND: Psoriasis is an immune-mediated, inflammatory disease. Adipokines contribute to the regulation of immune-mediated processes and inflammation. OBJECTIVE: The aim of our study was to systematically review the literature for studies that have evaluated the circulating concentrations of adipokines in patients with psoriasis and controls and to meta-analyze the best evidence available. METHODS: Eligible were studies that have assessed leptin, resistin, or adiponectin concentrations in psoriatic patients and a reference group...
December 13, 2017: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/29216643/emerging-treatment-options-in-atopic-dermatitis-topical-therapies
#11
Uffe Nygaard, Mette Deleuran, Christian Vestergaard
Atopic dermatitis is a chronic inflammatory skin disorder affecting children and adults, with the majority presenting mild to moderate disease severity. The use of topical corticosteroids (TCSs) in combination with emollients has been the mainstay for treating mild to moderate atopic dermatitis since the 1950s, and as a supplement to systemic treatment in severe disease. However, while very effective, TCSs are often accompanied by poor adherence due to corticophobia (fear of using corticosteroids in patients or doctors), unwanted side effects, and in some cases insufficient clinical response...
December 8, 2017: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/29212074/late-onset-alopecia-areata-a-retrospective-cohort-study
#12
Anna Lyakhovitsky, Sarit Gilboa, Anna Eshkol, Aviv Barzilai, Sharon Baum
BACKGROUND: Alopecia areata is an immune-mediated disease presenting with sudden onset of nonscarring hair loss. Onset is more common earlier in life, and little is known regarding late-onset alopecia areata. OBJECTIVES: To describe the epidemiology, clinical patterns, disease course, and outcome of late-onset alopecia areata in Israeli patients referred to a tertiary medical center. MATERIALS AND METHODS: This retrospective cohort study considered patients whose disease onset occurred at age ≥50 years...
December 7, 2017: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/29212071/palmar-telangiectasias-a-cutaneous-sign-for-smoking
#13
Assi Levi, Ronen Shechter, Moshe Lapidoth, Claes D Enk
BACKGROUND: Telangiectasias are permanent dilations of blood capillaries which appear in a variety of medical conditions. Cutaneous palmar telangiectasias have been postulated to be associated with smoking. OBJECTIVE: To determine whether a significant correlation exists between palmar telangiectasias and smoking habits. PATIENTS AND METHODS: A total of 124 volunteers participated in this observational study by allowing physical evaluation of their palms and by completing a questionnaire...
December 7, 2017: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/29190629/suppressed-adiponectin-levels-and-increased-adiponectin-response-to-oral-glucose-load-in-lean-women-with-severe-acne-normalizes-after-isotretinoin-treatment
#14
Kadriye Aydin, Fatma Çetinözman, Gonca Elcin, Duygu Yazgan Aksoy, Fatma Ucar, Bulent O Yildiz
BACKGROUND/AIM: Isotretinoin, the drug of choice for severe acne, might be associated with a decrease in insulin sensitivity. Adiponectin is an adipose tissue-derived protein that increases insulin sensitivity. In this study, we aimed to investigate adiponectin levels in postadolescent severe acne and the effect of isotretinoin on adiponectin levels. METHODS: Participants included 18 female patients with severe acne and 18 healthy women matched for age and body mass index (BMI)...
December 1, 2017: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/29169156/folliculotropism-does-not-affect-overall-survival-in-mycosis-fungoides-results-from-a-single-center-cohort-and-meta-analysis
#15
Mariah Giberson, Ahmed Mourad, Robert Gniadecki
BACKGROUND: Folliculotropic mycosis fungoides (FMF) is a distinct subtype of mycosis fungoides (MF) with unique clinicopathological features. The medical literature suggests that FMF has a more aggressive course and worse survival than classic MF. Previous studies do not use standardized treatment, and no studies have reported an association between treatment response and overall survival (OS). OBJECTIVE: To compare OS for MF, FMF, and Sézary syndrome (SS) patients...
November 24, 2017: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/29136636/screening-of-skin-lesion-associated-genes-in-patients-with-psoriasis-by-meta-integration-analysis
#16
Rong Mei, Xiaofeng Mei
AIM: Psoriasis is an inflammatory skin disease, and approximately one quarter of individuals with psoriasis develop painful and debilitating arthritis. As a complex and polygenetic hereditary disease, it is significant to investigate skin lesion-associated genes of psoriasis. METHOD: In the present study, a total of 3,047 differentially expressed genes between lesional and nonlesional skin of psoriasis patients were screened based on 4 data sets in GEO DataSets...
November 15, 2017: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/29130957/clinical-disease-patterns-in-a-regional-swiss-cohort-of-34-pyoderma-gangrenosum-patients
#17
Antonios G A Kolios, Alissa Gübeli, Barbara Meier, Julia-Tatjana Maul, Thomas Kündig, Jakob Nilsson, Jürg Hafner, Emmanuella Guenova, Katrin Kerl, Mark Anliker, Werner Kempf, Alexander A Navarini, Lars E French, Antonio Cozzio
BACKGROUND/AIM: Pyoderma gangrenosum (PG) is a rare, neutrophilic dermatosis often associated with an underlying disease, and clinical data or larger studies are rare. METHODS: In this retrospective study, disease characteristics, clinical manifestations, and treatment response were evaluated in a Swiss cohort of PG patients. RESULTS: In participating centers, 34 cases (21 females) of PG were analyzed based on clinical and histological presentation between 2002 and 2012...
November 7, 2017: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/29069641/diagnosis-of-inherited-epidermolysis-bullosa-in-resource-limited-settings-immunohistochemistry-revisited
#18
Vamsi Krishna Yenamandra, Neetu Bhari, Subrata Basu Ray, Vishnubhatla Sreenivas, Amit Kumar Dinda, Vinod Scaria, Vinod Kumar Sharma, Gomathy Sethuraman
BACKGROUND: Immunofluorescence (IFM) antigen mapping is the most commonly used technique to diagnose and differentiate epidermolysis bullosa (EB). In India, IFM is limited to few research laboratories and is not readily available, making the diagnosis largely clinical and often inaccurate. Ob jective of the Study: To examine the diagnostic usefulness of immunohistochemistry (IHC) as compared to IFM in resource-limited settings. METHODS: Forty-four consecutive EB patients were included in this study...
October 26, 2017: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/29040970/use-of-dipeptidyl-peptidase-iv-inhibitors-and-bullous-pemphigoid
#19
Clara Schaffer, Thierry Buclin, Francois R Jornayvaz, Simone Cazzaniga, Luca Borradori, Michel Gilliet, Laurence Feldmeyer
No abstract text is available yet for this article.
October 18, 2017: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/28992624/how-to-train-to-discharge-a-dermatology-outpatient-a-review
#20
A Harun, Andrew Y Finlay, M Sam Salek, Vincent Piguet
BACKGROUND/AIMS: The decision to discharge is a critical and common outpatient consultation event. However, little guidance exists over how discharge decision-making can be taught. We aimed to provide educational recommendations concerning outpatient discharge decision-making. METHODS: Recommendations were drawn from prior interviews with 40 consultant dermatologists and 56 dermatology outpatients, and from the "traffic light" design discharge information checklist, developed using the Delphi technique...
October 10, 2017: Dermatology: International Journal for Clinical and Investigative Dermatology
journal
journal
30954
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"