Nilton A S Neto, Tawanny K B Aguiar, Rayara J P Costa, Felipe P Mesquita, Lais L B de Oliveira, Maria E A de Moraes, Raquel C Montenegro, Rômulo F Carneiro, Celso S Nagano, Cleverson D T Freitas, Pedro F N Souza
Staphylococcus aureus forms biofilms, a structure that protects bacterial cells, conferring more resistance to difficult treatment. Synthetic peptides surge as an alternative to overcome the biofilm of multidrug-resistant pathogens. Mo -CBP3 -PepI, when combined with Ciprofloxacin, reduced preformed S. aureus biofilm by 50% at low concentrations (0.2 and 6.2 μg. mL-1 , respectively). The goal of this study was to evaluate the proteomic profile of biofilms after treatment with the Mo -CBP3 -PepI combined with ciprofloxacin...
November 13, 2023: Biofouling