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Acta Diabetologica

Amal Akour, Violet Kasabri, Nailya Boulatova, Yasser Bustanji, Randa Naffa, Dana Hyasat, Nahla Khawaja, Haidar Bustanji, Ayman Zayed, Munther Momani
AIMS: Type 2 diabetes mellitus (T2DM) and prediabetes (pre-DM) are associated with changes in levels of metabolic markers. The main aim of this study is to compare the levels of omentin, irisin, endothelin-1, nesfatin, hepatocyte growth factor (HGF), fibroblast growth factor, and oxytocin (OXT) between normoglycemic and pre-DM/T2DM obese Jordanian patients. METHODS: One hundred and ninety-eight adult Jordanian subjects were recruited. Demographic data and clinical parameters were collected...
October 18, 2016: Acta Diabetologica
Andrea E Scaramuzza, Claudia Arnaldi, Valentino Cherubini, Elvira Piccinno, Ivana Rabbone, Sonia Toni, Stefano Tumini, Gliberto Candela, Paola Cipriano, Lucia Ferrito, Lorenzo Lenzi, Davide Tinti, Ohad Cohen, Fortunato Lombardo
No abstract text is available yet for this article.
October 15, 2016: Acta Diabetologica
Davide Tinti, Salvatore Garofalo, Antonella Lezo, Jurgen Schleef, Ivana Rabbone
No abstract text is available yet for this article.
October 14, 2016: Acta Diabetologica
John E Madias
No abstract text is available yet for this article.
October 14, 2016: Acta Diabetologica
Matteo Monami, Ilaria Dicembrini, Edoardo Mannucci
No abstract text is available yet for this article.
October 11, 2016: Acta Diabetologica
Irene Marzona, Fausto Avanzini, Giuseppe Lucisano, Mauro Tettamanti, Marta Baviera, Antonio Nicolucci, Maria Carla Roncaglioni
AIMS: To verify whether it is possible, in people with diabetes mellitus (DM) considered at very high cardiovascular (CV) risk, stratify this risk better and identify significant modifiable risk factor (including lifestyle habits) to help patients and clinicians improve CV prevention. METHODS: People with DM and microvascular diseases or one or more CV risk factors (hypertension, hyperlipidemia, smoking, poor dietary habits, overweight, physical inactivity) included in the Risk and Prevention study were selected...
October 7, 2016: Acta Diabetologica
Antonino De Lorenzo, Sergio Bernardini, Paola Gualtieri, Andrea Cabibbo, Marco Alfonso Perrone, Ilio Giambini, Laura Di Renzo
AIMS: Inflammation and oxidative damage contribute significantly to the development of cardiovascular diseases (CVD). Postprandial oxidative stress and inflammation are characterized by an increased susceptibility of the organism toward oxidative damage after consumption of a meal rich in lipids and/or carbohydrates. Micronutrients modulate immune system and exert a protective action by reducing oxidized low-density lipoprotein (ox-LDL) level. The aim of the present study was to evaluate the postprandial plasma ox-LDL level and the gene expression of 13 genes related to oxidative stress (HOSp) and human inflammasome pathways (HIp), after a tocopherol-enriched Mediterranean meal (TEM), and a Western high-fat meal (HFM)...
October 5, 2016: Acta Diabetologica
Apolonia García-Patterson, Inka Miñambres, Juan María Adelantado, Ignasi Gich, Teresa Puig, Alberto de Leiva, Rosa Corcoy
AIMS: To assess the association between maternal diabetes characteristics and sex ratio at birth (SRB) in women with type 1 diabetes mellitus. METHODS: We performed a case-control study. The study subjects were infants born alive to women with type 1 diabetes and singleton pregnancies. Cases and controls were defined as male and female newborns, respectively. SRB was analysed according to diabetes-related characteristics adjusting in a logistic regression analysis for maternal characteristics known to affect SRB in the general population...
October 1, 2016: Acta Diabetologica
Heming Guo, Chen Fang, Yun Huang, Honghong Zhang, Xiaohong Chen, Duanming Hu, Ji Hu
No abstract text is available yet for this article.
October 1, 2016: Acta Diabetologica
Federica Barutta, Graziella Bruno, Giuseppe Matullo, Nish Chaturvedi, Serena Grimaldi, Casper Schalkwijk, Coen D Stehouwer, John H Fuller, Gabriella Gruden
AIMS: Increasing evidence suggests a potential role of circulating miRNAs as clinical biomarkers, and loss of miRNA-126 has been proposed as a predictor of type 2 diabetes onset. However, a systematic analysis of circulating miRNAs in type 1 diabetic patients with micro-/macrovascular complications has not yet been performed. METHODS: A cross-sectional nested case-control study from the EURODIAB Prospective Complications Study of 455 type 1 diabetic patients was performed...
October 1, 2016: Acta Diabetologica
Mohadeseh Sani, Erfan Ayubi, Salman Khazaei, Kamyar Mansori
No abstract text is available yet for this article.
October 1, 2016: Acta Diabetologica
Melissa Leung, Vincent W Wong, Ertugrul Durmush, Victoria Phan, Mikey Xie, Dominic Y Leung
AIMS: Weight loss in obese patients leads to improved left ventricular (LV) function. It is unclear whether improving glycaemic control has additional benefits to weight loss alone in patients with type 2 diabetes, or if benefits of weight loss are mediated through improving glycaemic control. This case-control study examined the incremental impact of these approaches on LV function. METHODS: Three groups of age, gender, and baseline HbA1c-matched patients with type 2 diabetes and suboptimal glycaemic control were followed-up for 12 months...
October 1, 2016: Acta Diabetologica
Hai-Bin Wu, Hao Wang, Ru-Ying Hu, Jie-Ming Zhong, Yi-Jian Qian, Chun-Mei Wang, Kai-Xu Xie, Ling-Li Chen, Wei-Wei Gong, Yu Guo, Zheng Bian, Zheng-Ming Chen, Li-Ming Li, Min Yu
AIMS: To evaluate the association between sleep duration, snoring and diabetes according to gender and menopausal status in rural China. METHODS: The data were part of the baseline survey of China Kadoorie Biobank, from a rural county in the south-east costal Zhejiang province. Participants including 24,027 men and 33,677 women aged 30-79 years were enrolled during 2004-2008. Multivariable logistic regression was used to calculate adjusted odds ratios (ORs) and 95 % confidence intervals (CIs) for diabetes...
September 24, 2016: Acta Diabetologica
Kochanowski Janusz, Piatkowski Radoslaw, Budnik Monika, Jasik Mariusz, Roik Marek, Opolski Grzegorz
We describe a case of an elderly woman who was diagnosed with a biventricular takotsubo cardiomyopathy (TTC) with combination of emotional stress and poorly controlled type 2 diabetes. We observed significant correlation between biphasic improvement of right (after 4 days) and left ventricle function (after 4 weeks) with normalization glycemic status. To our knowledge, this is the first reported case in the literature of biventricular TTC with such metabolic disturbances.
September 24, 2016: Acta Diabetologica
Xiaochun Yang, Jianbiao Xu, Jun Liu, Ninghua Ni, Yan Mei, Huo Lei, Juanjuan Wang, Ben Niu
AIMS: To investigate the protective effect of acetagastrodin on visual electrophysiology in patients with early-stage diabetes. METHODS: A prospective, randomized, controlled, double-blind trial was conducted. Subjects who were randomly assigned to either the treatment group or the control group were orally administered acetagastrodin or placebo, respectively, for 6 months. The quantity, mean amplitude and mean latency of oscillatory potentials (OPs) wavelets at baseline and 6 months were measured on electroretinogram (ERG), in all subjects...
September 20, 2016: Acta Diabetologica
Erin McKergow, Lianne Parkin, David J Barson, Katrina J Sharples, Benjamin J Wheeler
AIMS: Insulin pumps have been publically funded in New Zealand since 2012 for patients who meet certain clinical criteria; however, the patterns of utilization have not been described. We undertook a nationwide study to estimate the annual proportions of patients with type 1 diabetes mellitus who used a pump between 2012 and 2014, overall, and according to sex, age, ethnicity, socioeconomic position, and region. METHODS: We used data from the New Zealand Virtual Diabetes Register and routinely collected national demographic, health, and pharmaceutical dispensing data from the Ministry of Health to identify patients with type 1 diabetes and to calculate the overall, and subgroup, proportions using pumps...
September 20, 2016: Acta Diabetologica
M Songini, C Mannu, C Targhetta, G Bruno
Type 1 diabetes (T1D) results from an autoimmune destruction of insulin-producing beta cells that requires lifelong insulin treatment. While significant advances have been achieved in treatment, prevention of complications and quality of life in diabetic people, the identification of environmental triggers of the disease is far more complex. The island of Sardinia has the second highest incidence of T1D in the world (45/100,000), right after Finland (64.2/100,000). The genetic background as well as the environment of the island's inhabitants makes it an ideal region for investigating environmental, immunological and genetic factors related to the etiopathogenesis of T1D...
September 17, 2016: Acta Diabetologica
Rodolfo Guardado-Mendoza, Alberto O Chávez, Lilia M Jiménez-Ceja, Andrea Hansis-Diarte, Ralph A DeFronzo, Franco Folli, Devjit Tripathy
AIMS: Pancreatic islet amyloid deposition is a characteristic feature of type 2 diabetes mellitus (T2DM). Islet amyloid polypeptide (IAPP) is co-secreted with insulin, but its secretion profile and relationship to insulin and C-peptide in response to glucose and non-glucose stimuli has not been clearly defined. METHODS: Forty subjects (13 NGT, 12 IGT and 15 T2DM) participated in an OGTT and two-step hyperglycemic (225 and 400 mg/dl) clamp (80 min/step) followed by an IV arginine bolus...
September 13, 2016: Acta Diabetologica
Sarah S Farabi, David W Carley, Rand T Akasheh, Lauretta Quinn
No abstract text is available yet for this article.
September 13, 2016: Acta Diabetologica
Ronak Karbalaeifar, Sara Kazempour-Ardebili, Parisa Amiri, Shima Ghannadi, Zhale Tahmasebinejad, Atieh Amouzegar
AIMS: Type 2 diabetes mellitus is a common disease imposing a great economic burden to health systems. As the prevalence of type 2 diabetes in Iran has grown over the past decades, it has become necessary to evaluate the level of knowledge, attitude and practice of type 2 diabetic patients in our country for policy planning to increase the patients' awareness of diabetes and its complications and, in the long run, decrease costs of treatment. The aim of this study was to evaluate the level of knowledge, attitude and practice of patients with diabetes and its relationship with self-managing of disease and quality of life...
September 13, 2016: Acta Diabetologica
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