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Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie

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https://www.readbyqxmd.com/read/28174818/letter-to-the-editor-multinucleated-cells-in-parotid-warthin-tumor-a-potential-diagnostic-pitfall
#1
Adriana Handra-Luca
No abstract text is available yet for this article.
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28174817/an-underrated-personality-of-the-cluj-school-of-pathology-alexandru-serban-1920-1977
#2
Dan Cristian Bârsu, Marina Bârsu
The Romanian School of Pathology from Cluj has an important prestige, well known in Romania and abroad. It was founded in the same year with the Romanian Faculty of Medicine from the same City. The founder of the School of Pathology was Victor Babes (1854-1926). In 1920, his role was continued by his remarkable pupil Titu Vasiliu (1885-1961). Unfortunately, a personality of this School of Pathology rarely mentioned is Alexandru Serban (1920-1977). He was pupil of T. Vasiliu and he led the Department of Pathology from the Cluj Faculty of Medicine between 1973 and 1977...
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28174816/diagnosis-problems-in-a-case-of-ovarian-tumor-case-presentation
#3
Dinu Florin Albu, Cristina CrenguŢa Albu, Constantin Cristian Văduva, Mihaela Niculescu, Antoine Edu
Ovarian epithelial tumors are the most common ovarian neoplasms, standing for more than half of all ovarian tumors. Borderline ovarian tumors represent a distinct group recognized by the World Health Organization (WHO), histologically distinct low ovarian carcinomas. They are tumors with low grade of malignancy with good progress and prognosis. The authors present a case of an ovarian tumor with diagnosis problems. It was the case of a 38-year-old patient with no genital pathological history, presenting hypogastric pain, dysmenorrhea, abdominal distension...
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28174815/metachronous-gastrointestinal-stromal-tumor-associated-with-other-neoplasia-case-presentation
#4
Laura Florentina Rebegea, Anca Pătraşcu, Dumitra Miron, Mihaela Emilia Dumitru, Dorel Firescu
The association of gastrointestinal stromal tumor (GIST), synchronous or metachronous with other tumors is reported in special literature, the most frequent being associated with other gastrointestinal tumors. GISTs are the most common mesenchymal neoplasm of the gastro-intestinal tract with a malignant potential. We present a case of 68-year-old male patient diagnosed with GIST stage IV, unreachable due to liver metastases, treated with Imatinib, diagnosed at 13 months of prostate adenocarcinoma diagnosis [treated with hormonal therapy (HT) and external beam radiotherapy (EBRT)]; at 45 months from the first neoplasia diagnosis, the patient was diagnosed with the third neoplasia - lung squamous carcinoma - right inferior lobe, for which performed EBRT...
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28174814/morphological-and-ultrasonographic-study-of-fetuses-with-cervical-hygroma-a-cases-series
#5
Octavian Munteanu, Monica Mihaela Cîrstoiu, Florin Mihail Filipoiu, Roxana Elena BohîlŢea, Ioan Alexandru Bulescu, Costin Berceanu
Cystic cervical hygroma or cervical cystic lymphangioma is a congenital benign disease of the lymphatic system that is characterized by the accumulation of lymph in the jugular lymphatic sacs of the nuchal region. The factor that causes this pathology is not clarified yet but the physiopathological mechanism seems to be multifactorial. The incidence and prevalence of cervical hygroma are increased in patients with Turner syndrome, Down syndrome, Klinefelter syndrome, Edwards syndrome, Patau syndrome, Noonan syndrome, pterygium syndrome, Cantrell pentalogy, Fryns syndrome, Apert syndrome, Pena-Shokeir syndrome and achondroplasia...
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28174813/isolated-anomalies-of-the-fetal-hand-two-case-reports-and-a-review-of-the-literature
#6
Claudiu Mărginean, Claudiu Molnar-Varlam, Lorena Elena MeliŢ, Maria Oana Mărginean, VlăduŢ Ştefan Bogdan Săsăran, Daniel Mureşan
Fetal ultrasonography remains the main diagnostic tool for the assessment of different malformation. Fetal limb anomalies can be either isolated, either associated with other malformations in context of different syndromes. We present two cases of isolated fetal limb anomalies involving the distal part of the upper limb, namely the fetal hand consisting in phalangeal aplasia detected through routine ultrasound fetal examination. We could not identify the etiology in any of the cases, but in one of them, we discovered a bilateral thumb anomaly of the mother's hand...
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28174812/leiomyosarcoma-fnclcc-g3-pt2b-of-broad-ligament-adherent-to-right-oviduct-case-report-with-molecular-profiling
#7
Andrzej Wincewicz, Artur Kowalik, Sebastian Zięba, Stanisław Góźdź, Martyna Woltanowska
Here we present a report of 61-year-old female patient. Uterus with left appendages was removed together with clinically tagged "tumor of right ovary" and then extensively sampled and routinely processed with Hematoxylin-Eosin (HE) and some additional staining. There was discernible oviduct adherent to grayish, solid, polycyclic 22 cm in diameter focally necrotic tumor to be diagnosed high-grade conventional leiomyosarcoma FNCLCC (Fédération Nationale des Centres de Lutte Contre le Cancer) G3 pT2b, according to 7th edition pTNM, according to World Health Organization (WHO) 2013 International Classification of Diseases for Oncology (ICD-O): 8890÷3, in nearby of right oviduct...
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28174811/ovarian-teratomas-in-a-patient-with-bardet-biedl-syndrome-a-rare-association
#8
Irina Tica, Oana Sorina Tica, Alina Doina Nicoară, Vlad Iustin Tica, Andrei Adrian Tica
Bardet-Biedl syndrome (BBS) represents a rare ciliopathy recessive autosomal inherited. The main clinical features are retinal dystrophy, postaxial polydactyly, obesity, different degrees of cognitive deficit, renal impairment, hypogonadism and genital malformations. The genetic explanation consists in BBS genes mutations, which encode modified proteins, altering the function of the immotile cilia. As a multitude of BBS genes mutations were described, the phenotypic aspect of these disorders varies according to that...
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28174810/severe-upper-gastrointestinal-bleeding-from-gastrointestinal-stromal-tumor-of-the-stomach
#9
LaurenŢiu Augustus Barbu, Nicolae Dragoş Mărgăritescu, Mirela Corina Ghiluşi, Daniel Belivacă, Eugen Florin Georgescu, Ştefan Mugurel Ghelase, Daniela Marinescu
Gastrointestinal stromal tumor (GIST) is a mesenchymal tumor originating from the Cajal interstitial cells, immunologically characterized by the c-kit gene. The evolution may be asymptomatic, discovered by chance during a necropsy, upper gastrointestinal endoscopy or due to complications of type-algic, occlusive or hemorrhage. We present the case of a voluminous gastric GIST complicated with serious upper gastrointestinal bleeding in a patient with multiple hard associated diseases, undergoing an emergency surgery in hemorrhagic shock...
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28174809/intracranial-immature-teratoma-with-a-primitive-neuroectodermal-malignant-transformation-case-report-and-review-of-the-literature
#10
Carmen Georgiu, Iulian Opincariu, Cristina Ligia Cebotaru, Ştefan Claudiu Mirescu, Bogdan Petre Stănoiu, Teodora Ana Maria Domşa, Alina Simona Şovrea
INTRODUCTION: Central nervous system (CNS) germ cell tumors are very rare, accounting for 0.3-3% of primary intracranial neoplasms; of these, the teratomas are even more uncommon. The immature variant of teratomas, defined by the presence of incompletely differentiated components resembling fetal tissues is considered as having a low, almost borderline malignancy state. CASE PRESENTATION: A 35-year-old male presented with a left fronto-basal tumor. At surgery, a grey white tumor, mostly solid, was excised...
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28174808/lymph-node-tuberculosis-after-melanoma-treatment-sometimes-the-patient-is-lucky
#11
Cristina Călăraşu, Isabela Siloşi, Augustin Mircea Cupşa, Ileana Octavia Petrescu, Costin Teodor Streba, Viorel Biciuşcă, Maria ForŢofoiu, Dragoş Marian Popescu
Tuberculosis (TB) is considered a pulmonary disease that can however disseminate to other organs through hematogenous dissemination following primary TB infection. Evolution of the disease can either be precocious, before healing of the primary infection, or late after primary infection, due to reactivation of initial lesions usually because of simultaneous immunosuppressive factors such as diabetes, renal disease, hepatic disease or different type of immunosuppressing treatments. Rare cases when tuberculosis and cancer are diagnosed at the same time create diagnostic difficulties and therapeutic challenges...
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28174807/surgical-pathology-management-and-outcome-in-the-vulvar-melanoma-associated-with-abdominal-mass-a-case-report
#12
Costin Berceanu, Florinel Pop, Claudia MehedinŢu, Monica Mihaela Cîrstoiu, Răzvan Ciortea, Sabina Berceanu, Ioana Andreea Gheonea, Elvira Brătilă
Vulvar malignant melanomas are extremely rare neoplasms, representing less than 3% of all cancers in women, 9% of all external genital tract malignancies and 9% of all primary vulvar malignancies. We present the case of a 60-year-old Caucasian patient, who has been admitted in the Clinic of Obstetrics and Gynecology with polymorphic, vulvar local, pelvic-abdominal, genitourinary and general symptoms, being diagnosed with nodular and superficial spreading vulvar melanoma and multiple voluminous uterine leiomyoma with various degenerations...
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28174806/a-particular-case-of-cytomegalovirus-infection-in-infancy
#13
Ramona Florina Stroescu, Rodica Ilie, Otilia Mărginean, Mihai Gafencu, Teofana Otilia Bizerea, Gabriela Simona Doroş
: The clinical spectrum of perinatal infection varies from asymptomatic infection or mild disease to severe systemic involvement. The aim of this paper is to present a severe intrauterine infection, which led to difficulties in diagnosis and unfavorable evolution. CASE PRESENTATION: M.E., 6-weeks-old, born small for gestational age, was admitted in our Hospital for gastrointestinal signs: diarrhea, abdominal distension, observed three days earlier. Clinical and biological exams revealed hepatic disease related with hepatic cytolysis and cholestasis...
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28174805/epithelioid-trophoblastic-tumor-a-case-report-and-literature-review
#14
Ruxandra Viorica Stănculescu, Vasilica Bauşic, Teodora Camelia Vlădescu, Florina Vasilescu, Elvira Brătilă
Epithelioid trophoblastic tumor (ETT) is a very rare case of malignant trophoblastic tumor, which can occur particularly during the fertile age of women with a long history of abortion and delivery. ETT originates from the intermediate trophoblastic cells of chorion laeve. The main features of this tumor include lack of vessels within the tumor, nuclear hyperchromasia and pleomorphism and a large zone of necrosis and hyalinization. The clinical features of ETT are specific to each case and often consist of vaginal bleeding or amenorrhea in the absence of other complains...
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28174804/optimizing-cryopreservation-of-mouse-embryonic-fibroblast-feeder-cell-layer-to-improve-production-of-murine-embryonic-stem-cell-outgrowth
#15
Nurin Farhanah Norzaiwin, Siew Ying Goh, Jien Wei Chung, Wan Embong Wan Khadijah, Ramli Bin Abdullah
The inconsistency of efficiency in murine embryonic stem cell (ESC) production might be associated with the differences in preparation and cryopreservation of the feeder cell layer. As the cryopreservation of mouse embryonic fibroblast (MEF) declined the quality of MEF as feeder cell layer, an effective protocol should be determined to produce murine ESC on frozen-thawed feeder cell layer as efficient on fresh feeder cell layer. Under appropriate culture conditions, isolated inner cell mass (ICM) of murine blastocyst will form ESC and be maintained in undifferentiated state...
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28174803/evaluation-of-cardiac-microvasculature-in-patients-with-diffuse-myocardial-fibrosis
#16
Octavian Istrătoaie, Ionica Pirici, Anca Maria OfiŢeru, Florin Grosu, Alice Brînzea, Lavinia Olar, Ion Cristian Efrem
Myocardial fibrosis is one of the most common histopathological lesions found in chronic heart diseases. Progressive development of myocardial fibrosis will cause heart failure, an extremely debilitating and life threatening condition. The correlation between the severity of fibrosis and myocardial microcirculation is an important prognostic factor in this disease entity. In our study, myocardial microvascular density evaluation of the patients with high blood pressure (hypertension), atrial fibrillation (AF), coronary heart disease, and heart failure showed a significant decrease of the values of this parameter, which means that myocardial fibrosis is the direct result of stimulation of myocardial fibroblasts induced by local hypoxia...
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28174802/-759c%C3%A3-t-polymorphism-of-the-htr2c-gene-is-not-correlated-with-atypical-antipsychotics-induced-weight-gain-among-romanian-psychotic-patients
#17
Raluca Claudia Grădinaru, Nicoleta Ioana Andreescu, Laura Alexandra Nussbaum, Simona Sorina Farcaş, Victor Dumitraşcu, Liana Suciu, Maria Puiu
We aim to investigate whether the -759C÷T polymorphism in 5-HTR2C gene was associated with weight change and hyperinsulinemia in Romanian pediatric patients with schizophrenia and bipolar disorders. The patients under investigation were enrolled between 2009 and 2014. A total of 81 schizophrenic and bipolar-disorder patients, aged between nine to 20 years (median age 15.74±4 years), who were following an atypical antipsychotic treatment (Risperidone, Aripiprazole, Olanzapine), were enrolled from University Hospital for Child and Adolescent Psychiatry and Neurology from Timisoara, Romania...
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28174801/the-experience-of-our-clinic-in-laparoscopy-for-adnexal-masses-and-the-correlation-between-ultrasound-findings-and-pathological-results
#18
Liana Pleş, Romina Marina Sima, Anca Burnei, Dinu Florin Albu, Mihaela Adriana Bujor, Stelian Conci, Valeriu Teodorescu, Antoine Edu
INTRODUCTION: An adnexal mass (mass of the ovary, Fallopian tube, or surrounding connective tissues) is a common gynecological problem. Ovarian pathology can occur at any time from fetal life to menopause. Sonography is a clinically important imaging modality for assessing whether an adnexal mass is likely benign or possibly malignant. Most ovarian surgeries are for benign disease and can be performed laparoscopically. PATIENTS, MATERIALS AND METHODS: We retrospectively evaluated all the patients from our Clinic who underwent laparoscopy for adnexal tumors in the last three year...
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28174800/prediction-of-motor-disorders-in-multiple-sclerosis-using-muscle-change-structure-assessment
#19
Marius Cristian NeamŢu, Oana Maria NeamŢu, Mihnea Ion Marin, Denisa Enescu Bieru, Ligia Rusu
INTRODUCTION: The neuropathogenesis of multiple sclerosis (MS) lesions has been explained by several mechanisms, which emphasize the unpredictable nature of these lesions. The aim of this study is to present the neuromuscular changes in MS at the patients without gait or motor disorders using a noninvasive method named tensiomyography (TMG). PATIENTS AND METHODS: The studied group included a number of seven MS patients without clinically detected gait disorders, with mean age of 33...
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28174799/periodontal-disease-in-diabetic-patients-clinical-and-histopathological-aspects
#20
Dorina Corlan Puşcu, Radu Constantin Ciuluvică, Andreea Anghel, Gheorghe Dan Mălăescu, Adina Nicoleta Ciursaş, Gabriel Valeriu Popa, Doriana Agop Forna, Cristina Jana Busuioc, Izabela Siloşi
Periodontal disease is one of the most frequent diseases affecting people all over the world. The relation between periodontal disease and diabetes mellitus raised the interest both of dentists and doctors treating metabolic diseases, as the two conditions influence one another. In our study, we analyzed a number of 75 patients with diabetes mellitus and periodontal disease that presented to the medical consultory for conditions of the dental maxillary system. The clinical study showed that periodontal disease and diabetes may affect young adults as well, still this pathological association more frequently appears after the age of 50...
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
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